YY1P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1actin nucleation (GO:0045010)8.95341305
2nucleoside transmembrane transport (GO:1901642)7.52664000
3DNA replication checkpoint (GO:0000076)7.46399118
4negative regulation of granulocyte differentiation (GO:0030853)7.13569377
5mitotic G2 DNA damage checkpoint (GO:0007095)7.05562282
6positive regulation of sodium ion transmembrane transporter activity (GO:2000651)6.89992671
7negative regulation of macrophage differentiation (GO:0045650)6.78498266
8microtubule nucleation (GO:0007020)6.71318161
9mitotic G2/M transition checkpoint (GO:0044818)6.45758767
10positive regulation of DNA-templated transcription, initiation (GO:2000144)5.82961677
11regulation of interleukin-12 biosynthetic process (GO:0045075)5.66124739
12neurotransmitter catabolic process (GO:0042135)5.50950096
13positive regulation of cytokinesis (GO:0032467)5.48188011
14nucleoside transport (GO:0015858)5.36977399
15positive regulation of sodium ion transmembrane transport (GO:1902307)5.32579160
16metallo-sulfur cluster assembly (GO:0031163)5.32044138
17iron-sulfur cluster assembly (GO:0016226)5.32044138
18positive regulation of histone H3-K4 methylation (GO:0051571)5.24004320
19regulation of monocyte differentiation (GO:0045655)4.87080339
20mannose metabolic process (GO:0006013)4.73315734
21regulation of nuclear cell cycle DNA replication (GO:0033262)4.72427298
22diaphragm development (GO:0060539)4.68113044
23centriole replication (GO:0007099)4.45063467
24N-acetylneuraminate metabolic process (GO:0006054)4.43712707
25beta-amyloid metabolic process (GO:0050435)4.42007357
26DNA strand elongation involved in DNA replication (GO:0006271)4.36652964
27negative regulation of heart rate (GO:0010459)4.32354826
28pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.18171904
29sensory perception of smell (GO:0007608)4.16257094
30DNA strand elongation (GO:0022616)4.11560625
31detection of chemical stimulus involved in sensory perception of smell (GO:0050911)4.10946897
32DNA replication initiation (GO:0006270)4.06369624
33skeletal muscle organ development (GO:0060538)4.05705786
34regulation of centriole replication (GO:0046599)4.01237673
35amyloid precursor protein metabolic process (GO:0042982)3.98992971
36regulation of lipoprotein particle clearance (GO:0010984)3.97044439
37regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)3.94052821
38organelle disassembly (GO:1903008)3.91959465
39negative regulation of telomerase activity (GO:0051974)3.88095603
40pyrimidine nucleotide catabolic process (GO:0006244)3.79863160
41monoubiquitinated protein deubiquitination (GO:0035520)3.78446998
42G2 DNA damage checkpoint (GO:0031572)3.74107444
43regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.71787936
44regulation of histone H3-K4 methylation (GO:0051569)3.71360726
45regulation of histone H3-K9 methylation (GO:0051570)3.62562491
46embryonic forelimb morphogenesis (GO:0035115)3.61589068
47ribonucleoprotein complex disassembly (GO:0032988)3.60466034
48protein K6-linked ubiquitination (GO:0085020)3.58011337
49positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)3.50857977
50osteoblast development (GO:0002076)3.41129354
51regulation of DNA-templated transcription, initiation (GO:2000142)3.40306171
52regulation of cytokinesis (GO:0032465)3.39353208
53regulation of granulocyte differentiation (GO:0030852)3.39338842
54negative regulation of organelle assembly (GO:1902116)3.36904687
55mature B cell differentiation involved in immune response (GO:0002313)3.35785917
56protein polyglutamylation (GO:0018095)3.34447825
57positive regulation of actin filament polymerization (GO:0030838)3.33141425
58regulation of cell communication by electrical coupling (GO:0010649)3.31058076
59positive regulation of prostaglandin secretion (GO:0032308)3.27856539
60mitotic nuclear envelope disassembly (GO:0007077)3.27183189
61mitochondrial RNA metabolic process (GO:0000959)3.20015114
62pseudouridine synthesis (GO:0001522)3.17634109
63phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.15409218
64double-strand break repair via homologous recombination (GO:0000724)3.13104116
65negative regulation of appetite (GO:0032099)3.13089803
66negative regulation of response to food (GO:0032096)3.13089803
67negative regulation of histone methylation (GO:0031061)3.10508627
68fucose metabolic process (GO:0006004)3.10181797
69embryonic hindlimb morphogenesis (GO:0035116)3.08327308
70DNA strand renaturation (GO:0000733)3.05949854
71N-acetylglucosamine metabolic process (GO:0006044)3.05920652
72recombinational repair (GO:0000725)3.04645053
73response to testosterone (GO:0033574)3.03010566
74RNA methylation (GO:0001510)3.00780566
75embryonic placenta development (GO:0001892)3.00249190
76regulation of double-strand break repair via homologous recombination (GO:0010569)2.99521145
77forelimb morphogenesis (GO:0035136)2.99351264
78fusion of sperm to egg plasma membrane (GO:0007342)2.99096576
79centrosome organization (GO:0051297)2.98757082
80snRNA transcription (GO:0009301)2.97799887
81retrograde transport, endosome to Golgi (GO:0042147)2.95799967
82regulation of spindle checkpoint (GO:0090231)2.95166344
83positive regulation of histone methylation (GO:0031062)2.93876464
84nuclear envelope disassembly (GO:0051081)2.90510804
85membrane disassembly (GO:0030397)2.90510804
86synaptic transmission, cholinergic (GO:0007271)2.88299247
87centriole assembly (GO:0098534)2.86855678
88microtubule organizing center organization (GO:0031023)2.86104561
89neurotransmitter biosynthetic process (GO:0042136)2.84956636
90regulation of RNA export from nucleus (GO:0046831)2.80696144
91fucosylation (GO:0036065)2.75990232
92tachykinin receptor signaling pathway (GO:0007217)2.75415261
93nucleobase biosynthetic process (GO:0046112)2.74888896
94positive regulation of protein polymerization (GO:0032273)2.74766589
95negative regulation of DNA biosynthetic process (GO:2000279)2.74301725
96regulation of acrosome reaction (GO:0060046)2.73572088
97centrosome duplication (GO:0051298)2.72956826
98synaptonemal complex assembly (GO:0007130)2.72912703
99sleep (GO:0030431)10.2816951
100Arp2/3 complex-mediated actin nucleation (GO:0034314)10.1926664

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.79915411
2CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.82538186
3ZNF274_21170338_ChIP-Seq_K562_Hela3.32681423
4CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human3.09465809
5IGF1R_20145208_ChIP-Seq_DFB_Human2.82350162
6MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.55291141
7TP63_19390658_ChIP-ChIP_HaCaT_Human2.52690579
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.45061314
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.40233050
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.36357551
11ERG_21242973_ChIP-ChIP_JURKAT_Human2.27635977
12EBNA2_21746931_ChIP-Seq_IB4-LCL_Human2.21779649
13TP53_16413492_ChIP-PET_HCT116_Human2.02749522
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.98577508
15KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.98436053
16KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.98436053
17KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.98436053
18GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.92485669
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.91677441
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.90572068
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.89376952
22AR_21572438_ChIP-Seq_LNCaP_Human1.81495065
23SPI1_23127762_ChIP-Seq_K562_Human1.74819700
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.73685888
25EWS_26573619_Chip-Seq_HEK293_Human1.62018873
26MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58618764
27PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.58060274
28HOXB7_26014856_ChIP-Seq_BT474_Human1.56891643
29UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.48591689
30E2F1_21310950_ChIP-Seq_MCF-7_Human1.47941898
31DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.46351325
32SCL_19346495_ChIP-Seq_HPC-7_Human1.46118141
33HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.44545233
34VDR_23849224_ChIP-Seq_CD4+_Human1.41117830
35CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.40166234
36ETV2_25802403_ChIP-Seq_MESCs_Mouse1.32612774
37GABP_19822575_ChIP-Seq_HepG2_Human1.32520996
38YY1_22570637_ChIP-Seq_MALME-3M_Human1.30392768
39RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.30191198
40SALL1_21062744_ChIP-ChIP_HESCs_Human1.28707085
41SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.28048619
42EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.26715786
43MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.24102625
44KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.21205798
45TDRD3_21172665_ChIP-Seq_MCF-7_Human1.20841745
46FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.20416090
47GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.19196630
48OCT4_20526341_ChIP-Seq_ESCs_Human1.18770401
49ELK4_26923725_Chip-Seq_MESODERM_Mouse1.18282352
50OCT4_19829295_ChIP-Seq_ESCs_Human1.17050809
51LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.16683479
52SALL4_22934838_ChIP-ChIP_CD34+_Human1.15528458
53VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.15008299
54GATA1_19941826_ChIP-Seq_K562_Human1.14524709
55EZH2_22144423_ChIP-Seq_EOC_Human1.12965708
56VDR_21846776_ChIP-Seq_THP-1_Human1.11225378
57RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.11204584
58SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.11016812
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.10595643
60VDR_22108803_ChIP-Seq_LS180_Human1.09539910
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.09398116
62PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.08943247
63EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.06154756
64E2F1_17053090_ChIP-ChIP_MCF-7_Human1.05242514
65EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.03845965
66SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.03621514
67FOXP1_21924763_ChIP-Seq_HESCs_Human1.03033799
68ESR1_20079471_ChIP-ChIP_T-47D_Human1.03004103
69GATA3_21878914_ChIP-Seq_MCF-7_Human1.02097936
70JUN_21703547_ChIP-Seq_K562_Human1.01734148
71KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.98888317
72TCF4_23295773_ChIP-Seq_U87_Human0.98494348
73SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.98396629
74CBP_20019798_ChIP-Seq_JUKART_Human0.97885158
75IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97885158
76SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.96937737
77SRF_21415370_ChIP-Seq_HL-1_Mouse0.95983973
78SOX11_22085726_ChIP-Seq_ESNs_Mouse0.95320831
79CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94758465
80BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94482951
81DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.92847207
82TCF4_18268006_ChIP-ChIP_LS174T_Human0.92100138
83RAD21_21589869_ChIP-Seq_MESCs_Mouse0.91396897
84SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.90450060
85NCOR1_26117541_ChIP-Seq_K562_Human0.90211021
86PCGF2_27294783_Chip-Seq_NPCs_Mouse0.90110529
87TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.89600251
88TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.88388648
89ELK1_19687146_ChIP-ChIP_HELA_Human0.88296775
90PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.88064856
91WDR5_24793694_ChIP-Seq_LNCAP_Human0.86553918
92GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.86241989
93GATA1_22383799_ChIP-Seq_G1ME_Mouse0.84240626
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.83374666
95KLF4_19829295_ChIP-Seq_ESCs_Human0.82641973
96ETV1_20927104_ChIP-Seq_GIST48_Human0.82239026
97KAP1_27257070_Chip-Seq_ESCs_Mouse0.81694750
98MYC_19030024_ChIP-ChIP_MESCs_Mouse0.81609307
99GATA2_19941826_ChIP-Seq_K562_Human0.81372632
100CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.80766372

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003950_abnormal_plasma_membrane8.50053305
2MP0002102_abnormal_ear_morphology5.58967855
3MP0004885_abnormal_endolymph3.34125690
4MP0002009_preneoplasia2.53552188
5MP0003329_amyloid_beta_deposits2.47319400
6MP0006276_abnormal_autonomic_nervous2.27398076
7MP0008058_abnormal_DNA_repair2.26156999
8MP0003385_abnormal_body_wall2.09424951
9MP0003806_abnormal_nucleotide_metabolis11.9850818
10MP0003283_abnormal_digestive_organ1.93629951
11MP0009765_abnormal_xenobiotic_induced1.73285114
12MP0008057_abnormal_DNA_replication1.70516468
13MP0002928_abnormal_bile_duct1.62601085
14MP0005266_abnormal_metabolism1.62467702
15MP0005171_absent_coat_pigmentation1.56722459
16MP0009250_abnormal_appendicular_skeleto1.47289659
17MP0000372_irregular_coat_pigmentation1.44997580
18MP0003787_abnormal_imprinting1.42443860
19MP0000604_amyloidosis1.38908372
20MP0001529_abnormal_vocalization1.34996072
21MP0003252_abnormal_bile_duct1.30864599
22MP0008007_abnormal_cellular_replicative1.26084079
23MP0005174_abnormal_tail_pigmentation1.22434058
24MP0003632_abnormal_nervous_system1.19093787
25MP0005058_abnormal_lysosome_morphology1.18097760
26MP0003786_premature_aging1.17713110
27MP0003878_abnormal_ear_physiology1.09664822
28MP0005377_hearing/vestibular/ear_phenot1.09664822
29MP0004019_abnormal_vitamin_homeostasis1.09506509
30MP0008872_abnormal_physiological_respon1.03289251
31MP0002837_dystrophic_cardiac_calcinosis0.98342527
32MP0001873_stomach_inflammation0.97560495
33MP0001486_abnormal_startle_reflex0.96407317
34MP0005646_abnormal_pituitary_gland0.95126965
35MP0000462_abnormal_digestive_system0.95018671
36MP0004133_heterotaxia0.94962685
37MP0001881_abnormal_mammary_gland0.93769127
38MP0005551_abnormal_eye_electrophysiolog0.92408135
39MP0010094_abnormal_chromosome_stability0.90679858
40MP0008875_abnormal_xenobiotic_pharmacok0.88328123
41MP0003646_muscle_fatigue0.86722404
42MP0003111_abnormal_nucleus_morphology0.85941478
43MP0009046_muscle_twitch0.83727860
44MP0002733_abnormal_thermal_nociception0.83446055
45MP0002095_abnormal_skin_pigmentation0.82680006
46MP0003866_abnormal_defecation0.80391760
47MP0001984_abnormal_olfaction0.79784931
48MP0002938_white_spotting0.78159818
49MP0002249_abnormal_larynx_morphology0.77521097
50MP0008569_lethality_at_weaning0.76065472
51MP0000678_abnormal_parathyroid_gland0.75877319
52MP0002332_abnormal_exercise_endurance0.74528928
53MP0008877_abnormal_DNA_methylation0.73526895
54MP0000470_abnormal_stomach_morphology0.73471859
55MP0001666_abnormal_nutrient_absorption0.72163697
56MP0001929_abnormal_gametogenesis0.72130438
57MP0009745_abnormal_behavioral_response0.70631978
58MP0003698_abnormal_male_reproductive0.70298995
59MP0003300_gastrointestinal_ulcer0.68772471
60MP0003195_calcinosis0.67369946
61MP0000049_abnormal_middle_ear0.67173810
62MP0006292_abnormal_olfactory_placode0.66926555
63MP0003705_abnormal_hypodermis_morpholog0.64846653
64MP0009379_abnormal_foot_pigmentation0.64522070
65MP0002177_abnormal_outer_ear0.64117093
66MP0001661_extended_life_span0.60659866
67MP0005410_abnormal_fertilization0.60639903
68MP0008770_decreased_survivor_rate0.59414556
69MP0005376_homeostasis/metabolism_phenot0.59354972
70MP0005464_abnormal_platelet_physiology0.59242977
71MP0003935_abnormal_craniofacial_develop0.58566864
72MP0000367_abnormal_coat/_hair0.58551989
73MP0003633_abnormal_nervous_system0.57158978
74MP0003315_abnormal_perineum_morphology0.57104883
75MP0000920_abnormal_myelination0.56437627
76MP0001545_abnormal_hematopoietic_system0.54329075
77MP0005397_hematopoietic_system_phenotyp0.54329075
78MP0003718_maternal_effect0.53500556
79MP0003635_abnormal_synaptic_transmissio0.52317440
80MP0003631_nervous_system_phenotype0.51813159
81MP0008995_early_reproductive_senescence0.51474681
82MP0004742_abnormal_vestibular_system0.51360385
83MP0006054_spinal_hemorrhage0.50160972
84MP0003937_abnormal_limbs/digits/tail_de0.49371648
85MP0005167_abnormal_blood-brain_barrier0.48185771
86MP0001970_abnormal_pain_threshold0.46737602
87MP0004043_abnormal_pH_regulation0.45655238
88MP0002109_abnormal_limb_morphology0.45547536
89MP0005381_digestive/alimentary_phenotyp0.45046930
90MP0003077_abnormal_cell_cycle0.43731526
91MP0009278_abnormal_bone_marrow0.43138804
92MP0000747_muscle_weakness0.40610785
93MP0000026_abnormal_inner_ear0.40393624
94MP0002160_abnormal_reproductive_system0.40229948
95MP0002736_abnormal_nociception_after0.39352385
96MP0003656_abnormal_erythrocyte_physiolo0.39290477
97MP0002184_abnormal_innervation0.39207078
98MP0000432_abnormal_head_morphology0.38375507
99MP0002019_abnormal_tumor_incidence0.36807029
100MP0000681_abnormal_thyroid_gland0.36538284

Predicted human phenotypes

RankGene SetZ-score
1Aplasia cutis congenita (HP:0001057)7.14118856
2Abnormality of the aortic arch (HP:0012303)7.01415106
3Abnormality of the parietal bone (HP:0002696)5.84523915
4Rectovaginal fistula (HP:0000143)5.74236747
5Rectal fistula (HP:0100590)5.74236747
6Midline defect of the nose (HP:0004122)5.68415727
7Vaginal fistula (HP:0004320)5.40032968
8Intestinal fistula (HP:0100819)5.02024353
9Acute lymphatic leukemia (HP:0006721)5.00783772
10Limb hypertonia (HP:0002509)4.63953601
11Exostoses (HP:0100777)4.55987711
12Birth length less than 3rd percentile (HP:0003561)4.50794191
13Megalencephaly (HP:0001355)4.47255350
14Metaphyseal dysplasia (HP:0100255)4.41508312
15Large eyes (HP:0001090)4.36356962
16Aplasia/Hypoplasia of the sacrum (HP:0008517)4.03393958
17Median cleft lip (HP:0000161)3.93821850
18Abnormality of lateral ventricle (HP:0030047)3.91673157
19Breast hypoplasia (HP:0003187)3.91021619
20Abnormality of the pons (HP:0007361)3.84867546
21Pancreatic fibrosis (HP:0100732)3.72051003
22Hypoplasia of the pons (HP:0012110)3.64396365
23Abnormality of the renal collecting system (HP:0004742)3.62653491
24Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.59812163
25Skull defect (HP:0001362)3.51724967
26Tinnitus (HP:0000360)3.50404268
27Duplicated collecting system (HP:0000081)3.49730414
28Concave nail (HP:0001598)3.23532814
29Septate vagina (HP:0001153)3.22262500
30Pancreatic cysts (HP:0001737)3.11914418
31Aplasia of the musculature (HP:0100854)3.11393536
32Abnormality of cochlea (HP:0000375)3.09288111
33Thrombocytosis (HP:0001894)2.92735020
34Posterior subcapsular cataract (HP:0007787)2.92299764
35Patellar aplasia (HP:0006443)2.78916865
36Decreased skull ossification (HP:0004331)2.77262712
37Hypoplastic pelvis (HP:0008839)2.68759650
38Aplasia/Hypoplasia of the patella (HP:0006498)2.66891327
39Autoimmune thrombocytopenia (HP:0001973)2.63569216
40Hypoplastic nipples (HP:0002557)2.61739405
41Morphological abnormality of the inner ear (HP:0011390)2.61593695
42Fatigue (HP:0012378)2.58335825
43Split foot (HP:0001839)2.52501706
44Neoplasm of the peripheral nervous system (HP:0100007)2.49705619
45Scrotal hypoplasia (HP:0000046)2.46207638
46Facial hemangioma (HP:0000329)2.45573650
47Abnormality of the thoracic spine (HP:0100711)2.40950322
48Increased number of teeth (HP:0011069)2.40591833
49Germ cell neoplasia (HP:0100728)2.39101788
50Abnormality of skull ossification (HP:0002703)2.38531682
51Large for gestational age (HP:0001520)2.37853373
52Ependymoma (HP:0002888)2.36525369
53Tubulointerstitial nephritis (HP:0001970)2.34506366
54Abnormality of intracranial pressure (HP:0012640)2.29474797
55Increased intracranial pressure (HP:0002516)2.29474797
56Nephronophthisis (HP:0000090)2.29111268
57Capillary hemangiomas (HP:0005306)2.26293605
58IgA deficiency (HP:0002720)2.24962738
59Recurrent bacterial skin infections (HP:0005406)2.20248252
60Aplasia/Hypoplasia involving the musculature (HP:0001460)2.19840664
61Hyperlipoproteinemia (HP:0010980)2.18242830
62Neuroendocrine neoplasm (HP:0100634)2.07375133
63Annular pancreas (HP:0001734)2.04434225
64Abnormality of pyrimidine metabolism (HP:0004353)2.00563126
65Asymmetric growth (HP:0100555)1.95240408
66Pachygyria (HP:0001302)1.90873016
67Opisthotonus (HP:0002179)1.90591740
68Lower limb asymmetry (HP:0100559)1.88946019
69Ridged nail (HP:0001807)1.88424933
70Male pseudohermaphroditism (HP:0000037)1.88084423
71Hypoplasia of the corpus callosum (HP:0002079)1.86310713
72Chronic mucocutaneous candidiasis (HP:0002728)1.86225514
73Recurrent cutaneous fungal infections (HP:0011370)1.86225514
74Arteriovenous malformation (HP:0100026)1.85836460
75Fine hair (HP:0002213)1.85231136
76Increased corneal curvature (HP:0100692)1.82991659
77Keratoconus (HP:0000563)1.82991659
78Recurrent abscess formation (HP:0002722)1.81547147
79Muscular hypotonia of the trunk (HP:0008936)1.80872543
80Cerebral hypomyelination (HP:0006808)1.80721807
81Molar tooth sign on MRI (HP:0002419)1.77575774
82Abnormality of midbrain morphology (HP:0002418)1.77575774
83Abnormality of T cell physiology (HP:0011840)1.74591112
84Autoimmune hemolytic anemia (HP:0001890)1.69811554
85Long foot (HP:0001833)1.69661172
86Subcapsular cataract (HP:0000523)1.67458430
87Mitral regurgitation (HP:0001653)1.67067843
88Turricephaly (HP:0000262)1.65993282
89Abnormality of the renal medulla (HP:0100957)1.65557035
90Aplasia/Hypoplasia of the tongue (HP:0010295)1.65553139
91Bicornuate uterus (HP:0000813)1.62669345
92Hypertensive crisis (HP:0100735)1.62528591
93Short ribs (HP:0000773)1.62327537
94Long palpebral fissure (HP:0000637)1.62151364
95Type I transferrin isoform profile (HP:0003642)1.61907478
96Tetraparesis (HP:0002273)1.60903022
97Polymicrogyria (HP:0002126)1.59581361
98Recurrent skin infections (HP:0001581)1.59312873
99Bifid scrotum (HP:0000048)1.58676538
100Adrenal hypoplasia (HP:0000835)1.58047082

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK162.69756532
2MAPK132.34745630
3PINK12.01994640
4TAOK314.5318285
5PAK61.80845181
6TEC1.68364030
7NUAK11.59232484
8ALK1.54925226
9MAPK121.48934832
10BRD41.43022020
11TNK21.37031256
12IRAK31.12836838
13DAPK11.10310684
14MAPK111.09449732
15SIK21.08093222
16CDC71.05066002
17FRK1.04288272
18LATS11.03530553
19PDPK11.01421608
20CHEK20.99251419
21ADRBK20.97632724
22EEF2K0.89830966
23PDK10.88514213
24JAK30.84215911
25PASK0.84041485
26MST40.83004823
27EPHB20.82077504
28MAP2K30.79952644
29TXK0.79668022
30MAPK70.76623831
31ROCK20.74925125
32PAK20.72912786
33MAPKAPK30.71103051
34CDK190.68451702
35MAP3K70.66098365
36TTK0.56105923
37CSNK1A10.55800967
38MKNK20.53969160
39PNCK0.52044874
40TRPM70.51898875
41CSNK1E0.51068945
42CSNK1D0.50561106
43DMPK0.49763003
44STK30.49018759
45PLK40.47710997
46PKN10.47291732
47PRKAA10.47078023
48DAPK20.46909227
49GRK10.43513196
50JAK20.43441077
51BTK0.40645860
52WNK10.39561499
53MATK0.39025069
54PRKCQ0.39007433
55PLK10.38679700
56SYK0.37598817
57CHEK10.37370145
58MAP3K30.37118835
59CCNB10.35929268
60ATR0.35319689
61TGFBR20.35092874
62CDK30.34675599
63NEK20.34097470
64CDK20.33163342
65CDK10.30711984
66CAMK2B0.29501447
67MTOR0.28760143
68ATM0.28569423
69MAPK40.28403497
70MAPK140.27756619
71ADRBK10.27508045
72ITK0.27461617
73MAP4K10.27239710
74GSK3B0.27081467
75AURKA0.27021781
76BCKDK0.25093679
77MKNK10.24001294
78RPS6KB20.23695907
79CDK80.22676308
80MARK20.20047798
81CAMK2D0.19783988
82PTK60.18857020
83CDK40.18836349
84CAMK2G0.18101087
85ERBB40.17491201
86ZAK0.17206073
87RPS6KA30.17160595
88ERBB20.16648368
89PRKACA0.16600288
90MAPK10.16588370
91CSNK2A20.16357097
92AKT10.16279974
93CDK140.15719983
94MAPKAPK50.14996674
95OBSCN0.14580298
96INSRR0.14548281
97TBK10.14441610
98ABL10.13989725
99TLK10.13636847
100MAPK100.12619075

Predicted pathways (KEGG)

RankGene SetZ-score
1Homologous recombination_Homo sapiens_hsa034404.18057193
2Drug metabolism - other enzymes_Homo sapiens_hsa009834.04881897
3Sulfur relay system_Homo sapiens_hsa041223.99019407
4Olfactory transduction_Homo sapiens_hsa047403.37474841
5Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.94156475
6Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.74358718
7Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.48476816
8Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.35498810
9Taste transduction_Homo sapiens_hsa047422.34905231
10Maturity onset diabetes of the young_Homo sapiens_hsa049502.13459679
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.09920555
12Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.06613446
13Linoleic acid metabolism_Homo sapiens_hsa005911.98061750
14RNA transport_Homo sapiens_hsa030131.93814259
15Fructose and mannose metabolism_Homo sapiens_hsa000511.86713053
16Selenocompound metabolism_Homo sapiens_hsa004501.70697394
17Regulation of autophagy_Homo sapiens_hsa041401.66981884
18Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.61242190
19Intestinal immune network for IgA production_Homo sapiens_hsa046721.60328753
20Non-homologous end-joining_Homo sapiens_hsa034501.60250324
21Parkinsons disease_Homo sapiens_hsa050121.46109280
22DNA replication_Homo sapiens_hsa030301.45417543
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.37612126
24Acute myeloid leukemia_Homo sapiens_hsa052211.29848666
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.11096093
26Carbohydrate digestion and absorption_Homo sapiens_hsa049731.07997832
27Fanconi anemia pathway_Homo sapiens_hsa034601.07092278
28Basal transcription factors_Homo sapiens_hsa030221.03139306
29Steroid hormone biosynthesis_Homo sapiens_hsa001401.01199316
30Other glycan degradation_Homo sapiens_hsa005111.01142269
31Base excision repair_Homo sapiens_hsa034101.00515894
32Cholinergic synapse_Homo sapiens_hsa047250.97996226
33Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.96972347
34Pancreatic secretion_Homo sapiens_hsa049720.96443296
35Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.93640060
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.92849201
37Glycerophospholipid metabolism_Homo sapiens_hsa005640.88768025
38Alzheimers disease_Homo sapiens_hsa050100.87217199
39Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.86205207
40Ether lipid metabolism_Homo sapiens_hsa005650.84183065
41Jak-STAT signaling pathway_Homo sapiens_hsa046300.84114481
42Protein digestion and absorption_Homo sapiens_hsa049740.82206256
43Type II diabetes mellitus_Homo sapiens_hsa049300.81632609
44Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.78551026
45PI3K-Akt signaling pathway_Homo sapiens_hsa041510.75262796
46Glutathione metabolism_Homo sapiens_hsa004800.74381136
47Fat digestion and absorption_Homo sapiens_hsa049750.71985713
48Phototransduction_Homo sapiens_hsa047440.71074487
49Serotonergic synapse_Homo sapiens_hsa047260.71063162
50p53 signaling pathway_Homo sapiens_hsa041150.69198313
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.68512836
52Chronic myeloid leukemia_Homo sapiens_hsa052200.64563471
53Steroid biosynthesis_Homo sapiens_hsa001000.64153865
54Measles_Homo sapiens_hsa051620.63151613
55Oxidative phosphorylation_Homo sapiens_hsa001900.62833575
56Melanoma_Homo sapiens_hsa052180.61590610
57Pyrimidine metabolism_Homo sapiens_hsa002400.60687056
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.59932226
59Vascular smooth muscle contraction_Homo sapiens_hsa042700.56422876
60Ribosome_Homo sapiens_hsa030100.55795205
61T cell receptor signaling pathway_Homo sapiens_hsa046600.55156106
62Prolactin signaling pathway_Homo sapiens_hsa049170.54940113
63Platelet activation_Homo sapiens_hsa046110.53515296
64mRNA surveillance pathway_Homo sapiens_hsa030150.52706185
65Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.50931153
66AMPK signaling pathway_Homo sapiens_hsa041520.48809352
67Dorso-ventral axis formation_Homo sapiens_hsa043200.48122101
68Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47207805
69Retinol metabolism_Homo sapiens_hsa008300.46933234
70Cell cycle_Homo sapiens_hsa041100.46759952
71Nicotine addiction_Homo sapiens_hsa050330.45531307
72Salmonella infection_Homo sapiens_hsa051320.44525367
73Non-small cell lung cancer_Homo sapiens_hsa052230.44470107
74Purine metabolism_Homo sapiens_hsa002300.44254395
75Phospholipase D signaling pathway_Homo sapiens_hsa040720.43650550
76Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.43506409
77Choline metabolism in cancer_Homo sapiens_hsa052310.43154985
78Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42494978
79B cell receptor signaling pathway_Homo sapiens_hsa046620.39972256
80Renal cell carcinoma_Homo sapiens_hsa052110.38520114
81Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.37732958
82Viral carcinogenesis_Homo sapiens_hsa052030.36983324
83Chemical carcinogenesis_Homo sapiens_hsa052040.36820383
84Asthma_Homo sapiens_hsa053100.36784417
85Alcoholism_Homo sapiens_hsa050340.35663961
86Phosphatidylinositol signaling system_Homo sapiens_hsa040700.32888226
87Nitrogen metabolism_Homo sapiens_hsa009100.32688246
88TGF-beta signaling pathway_Homo sapiens_hsa043500.32572454
89Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.31590417
90Chemokine signaling pathway_Homo sapiens_hsa040620.31129539
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.31026432
92Pancreatic cancer_Homo sapiens_hsa052120.31000511
93Primary immunodeficiency_Homo sapiens_hsa053400.30762915
94RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.30247657
95Oxytocin signaling pathway_Homo sapiens_hsa049210.29948393
96Arachidonic acid metabolism_Homo sapiens_hsa005900.29204467
97Ovarian steroidogenesis_Homo sapiens_hsa049130.28472310
98Nucleotide excision repair_Homo sapiens_hsa034200.28086600
99Glioma_Homo sapiens_hsa052140.26539623
100Calcium signaling pathway_Homo sapiens_hsa040200.26183038

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »