

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of isotype switching to IgG isotypes (GO:0048302) | 6.45694869 |
| 2 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 6.45202288 |
| 3 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 6.33493448 |
| 4 | cellular response to interleukin-15 (GO:0071350) | 6.28872087 |
| 5 | response to interleukin-15 (GO:0070672) | 6.03868907 |
| 6 | negative T cell selection (GO:0043383) | 5.76676003 |
| 7 | tolerance induction (GO:0002507) | 5.70756451 |
| 8 | regulation of chronic inflammatory response (GO:0002676) | 5.36767481 |
| 9 | negative thymic T cell selection (GO:0045060) | 5.15296150 |
| 10 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 5.09517421 |
| 11 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.83196063 |
| 12 | regulation of regulatory T cell differentiation (GO:0045589) | 4.67886357 |
| 13 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.66102499 |
| 14 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.65987635 |
| 15 | negative regulation of interleukin-2 production (GO:0032703) | 4.64367206 |
| 16 | NIK/NF-kappaB signaling (GO:0038061) | 4.61753414 |
| 17 | activated T cell proliferation (GO:0050798) | 4.60999831 |
| 18 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.53782980 |
| 19 | negative regulation of T cell mediated immunity (GO:0002710) | 4.53226461 |
| 20 | thymic T cell selection (GO:0045061) | 4.51908365 |
| 21 | positive regulation of granulocyte differentiation (GO:0030854) | 4.50760682 |
| 22 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.44485335 |
| 23 | regulation of histone H3-K27 methylation (GO:0061085) | 4.44275005 |
| 24 | interferon-gamma production (GO:0032609) | 4.29566325 |
| 25 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 4.28311314 |
| 26 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 4.27067805 |
| 27 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 4.19636172 |
| 28 | positive regulation of immunoglobulin production (GO:0002639) | 4.08975057 |
| 29 | regulation of T cell tolerance induction (GO:0002664) | 4.08072148 |
| 30 | positive regulation of tolerance induction (GO:0002645) | 4.07005421 |
| 31 | regulation of immunoglobulin production (GO:0002637) | 4.03521069 |
| 32 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.99077876 |
| 33 | T cell selection (GO:0045058) | 3.95817968 |
| 34 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.95391484 |
| 35 | regulation of transforming growth factor beta1 production (GO:0032908) | 3.89352649 |
| 36 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.84914270 |
| 37 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.83151745 |
| 38 | regulation of interleukin-2 production (GO:0032663) | 3.82451907 |
| 39 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.79666117 |
| 40 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.79666117 |
| 41 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.78433950 |
| 42 | myeloid dendritic cell differentiation (GO:0043011) | 3.77682182 |
| 43 | positive regulation of macrophage activation (GO:0043032) | 3.75479419 |
| 44 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.70895347 |
| 45 | positive T cell selection (GO:0043368) | 3.67835193 |
| 46 | regulation of isotype switching (GO:0045191) | 3.67659307 |
| 47 | positive regulation of keratinocyte differentiation (GO:0045618) | 3.66154137 |
| 48 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.64960864 |
| 49 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.63415609 |
| 50 | cellular response to interleukin-4 (GO:0071353) | 3.62683435 |
| 51 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.60706126 |
| 52 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.60706126 |
| 53 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.58770493 |
| 54 | hemidesmosome assembly (GO:0031581) | 3.57351878 |
| 55 | tyrosine phosphorylation of STAT protein (GO:0007260) | 3.50891832 |
| 56 | positive regulation of interleukin-2 production (GO:0032743) | 3.47806351 |
| 57 | positive regulation of B cell mediated immunity (GO:0002714) | 3.47461546 |
| 58 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.47461546 |
| 59 | T cell apoptotic process (GO:0070231) | 3.47272402 |
| 60 | positive regulation of humoral immune response (GO:0002922) | 3.46876074 |
| 61 | DNA deamination (GO:0045006) | 3.44509852 |
| 62 | T cell homeostasis (GO:0043029) | 3.43233444 |
| 63 | positive regulation of cell killing (GO:0031343) | 3.42757579 |
| 64 | alpha-beta T cell differentiation (GO:0046632) | 3.41049918 |
| 65 | positive regulation of interleukin-4 production (GO:0032753) | 3.40378223 |
| 66 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.40089701 |
| 67 | myeloid dendritic cell activation (GO:0001773) | 3.39921773 |
| 68 | regulation of interleukin-5 production (GO:0032674) | 3.36390652 |
| 69 | necroptotic process (GO:0070266) | 3.35459304 |
| 70 | regulation of T cell chemotaxis (GO:0010819) | 3.31951793 |
| 71 | positive regulation of T cell chemotaxis (GO:0010820) | 3.31951793 |
| 72 | T cell lineage commitment (GO:0002360) | 3.31268609 |
| 73 | regulation of immunoglobulin secretion (GO:0051023) | 3.30534165 |
| 74 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 3.29650737 |
| 75 | positive regulation of isotype switching (GO:0045830) | 3.27985748 |
| 76 | regulation of RIG-I signaling pathway (GO:0039535) | 3.26779559 |
| 77 | positive thymic T cell selection (GO:0045059) | 3.26320877 |
| 78 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.20459888 |
| 79 | CD4-positive, alpha-beta T cell activation (GO:0035710) | 3.19604230 |
| 80 | positive regulation of lymphocyte mediated immunity (GO:0002708) | 3.19089178 |
| 81 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.17671610 |
| 82 | regulation of gamma-delta T cell activation (GO:0046643) | 3.16831904 |
| 83 | T cell proliferation (GO:0042098) | 3.16772987 |
| 84 | regulation of tolerance induction (GO:0002643) | 3.15899378 |
| 85 | alpha-beta T cell activation (GO:0046631) | 3.14032717 |
| 86 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.11009174 |
| 87 | response to interleukin-4 (GO:0070670) | 3.09957868 |
| 88 | regulation of B cell mediated immunity (GO:0002712) | 3.06434227 |
| 89 | type I interferon signaling pathway (GO:0060337) | 3.04788774 |
| 90 | cellular response to type I interferon (GO:0071357) | 3.04788774 |
| 91 | lymphocyte apoptotic process (GO:0070227) | 3.04590395 |
| 92 | regulation of translational termination (GO:0006449) | 3.03419919 |
| 93 | response to type I interferon (GO:0034340) | 3.02680018 |
| 94 | regulation of transforming growth factor beta production (GO:0071634) | 2.99338699 |
| 95 | regulation of vitamin metabolic process (GO:0030656) | 2.97112013 |
| 96 | negative regulation of interleukin-12 production (GO:0032695) | 2.95245198 |
| 97 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.94403273 |
| 98 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.94403273 |
| 99 | T cell differentiation involved in immune response (GO:0002292) | 2.94403273 |
| 100 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.94111027 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 8.63810187 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.37121816 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.48751582 |
| 4 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.20187419 |
| 5 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.10559705 |
| 6 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.31221691 |
| 7 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.01331122 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.89734612 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.73931592 |
| 10 | * MYB_26560356_Chip-Seq_TH2_Human | 2.72276912 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.67507190 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.58639662 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.45600889 |
| 14 | MAF_26560356_Chip-Seq_TH1_Human | 2.42132012 |
| 15 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.36193192 |
| 16 | MYC_22102868_ChIP-Seq_BL_Human | 2.35808116 |
| 17 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.28716832 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.23622453 |
| 19 | MYB_26560356_Chip-Seq_TH1_Human | 2.19723577 |
| 20 | MAF_26560356_Chip-Seq_TH2_Human | 2.11064972 |
| 21 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.03674569 |
| 22 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.98926067 |
| 23 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.82830298 |
| 24 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.78740959 |
| 25 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.76427188 |
| 26 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.72255071 |
| 27 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.70730199 |
| 28 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.68321359 |
| 29 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.68222583 |
| 30 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.67122235 |
| 31 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.63780267 |
| 32 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.63539533 |
| 33 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.61393230 |
| 34 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.61023463 |
| 35 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.60149273 |
| 36 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.59635163 |
| 37 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.57690009 |
| 38 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.52176371 |
| 39 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.47882189 |
| 40 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.46596861 |
| 41 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.45707917 |
| 42 | UTX_26944678_Chip-Seq_JUKART_Human | 1.45599252 |
| 43 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.45106985 |
| 44 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.41897953 |
| 45 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.34184222 |
| 46 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.29807609 |
| 47 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.29315931 |
| 48 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.28158602 |
| 49 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.26760948 |
| 50 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22025710 |
| 51 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.21989792 |
| 52 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.21440086 |
| 53 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.21344522 |
| 54 | GATA3_26560356_Chip-Seq_TH2_Human | 1.20559163 |
| 55 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.19983740 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17298697 |
| 57 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09114295 |
| 58 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.07932130 |
| 59 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06698924 |
| 60 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.04860531 |
| 61 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.04409218 |
| 62 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.00397470 |
| 63 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.99367336 |
| 64 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.98998156 |
| 65 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.98882520 |
| 66 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.98682485 |
| 67 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.97871763 |
| 68 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.97532247 |
| 69 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.97448296 |
| 70 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.95471433 |
| 71 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.95067012 |
| 72 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.95043945 |
| 73 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 0.92451000 |
| 74 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.89564952 |
| 75 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.88390861 |
| 76 | GATA1_22025678_ChIP-Seq_K562_Human | 0.88374645 |
| 77 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.88276070 |
| 78 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.87991324 |
| 79 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.86970174 |
| 80 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.86936592 |
| 81 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.86678733 |
| 82 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.84062176 |
| 83 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.83464441 |
| 84 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.83071402 |
| 85 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.82450206 |
| 86 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.81705160 |
| 87 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.79853956 |
| 88 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.79378289 |
| 89 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.77869326 |
| 90 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.76418926 |
| 91 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.74604027 |
| 92 | SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.73534497 |
| 93 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.72812274 |
| 94 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.72698759 |
| 95 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.72409961 |
| 96 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.72403886 |
| 97 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.72134186 |
| 98 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.71769909 |
| 99 | ATF3_27146783_Chip-Seq_COLON_Human | 0.71336808 |
| 100 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.71282226 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003763_abnormal_thymus_physiology | 5.10453512 |
| 2 | MP0009333_abnormal_splenocyte_physiolog | 4.33603162 |
| 3 | MP0001873_stomach_inflammation | 4.03677826 |
| 4 | MP0005671_abnormal_response_to | 3.88338832 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.52781467 |
| 6 | MP0001790_abnormal_immune_system | 3.27064117 |
| 7 | MP0005387_immune_system_phenotype | 3.27064117 |
| 8 | MP0002006_tumorigenesis | 3.02597190 |
| 9 | MP0002166_altered_tumor_susceptibility | 2.89260963 |
| 10 | MP0003436_decreased_susceptibility_to | 2.88090967 |
| 11 | MP0001800_abnormal_humoral_immune | 2.70443179 |
| 12 | MP0003300_gastrointestinal_ulcer | 2.69826359 |
| 13 | MP0005000_abnormal_immune_tolerance | 2.64818034 |
| 14 | MP0008057_abnormal_DNA_replication | 2.63724628 |
| 15 | MP0003866_abnormal_defecation | 2.44183615 |
| 16 | MP0009785_altered_susceptibility_to | 2.40525215 |
| 17 | MP0000703_abnormal_thymus_morphology | 2.28671039 |
| 18 | MP0003045_fibrosis | 2.28102933 |
| 19 | MP0000685_abnormal_immune_system | 2.24879931 |
| 20 | MP0005310_abnormal_salivary_gland | 2.23616769 |
| 21 | MP0002723_abnormal_immune_serum | 2.20694092 |
| 22 | MP0002398_abnormal_bone_marrow | 2.18035736 |
| 23 | MP0002420_abnormal_adaptive_immunity | 2.14544035 |
| 24 | MP0004381_abnormal_hair_follicle | 2.12080346 |
| 25 | MP0004947_skin_inflammation | 2.09175291 |
| 26 | MP0001819_abnormal_immune_cell | 2.07109140 |
| 27 | MP0002877_abnormal_melanocyte_morpholog | 2.02619277 |
| 28 | MP0002405_respiratory_system_inflammati | 1.99962612 |
| 29 | MP0002452_abnormal_antigen_presenting | 1.96050090 |
| 30 | MP0005025_abnormal_response_to | 1.88176106 |
| 31 | MP0000716_abnormal_immune_system | 1.87865053 |
| 32 | MP0002148_abnormal_hypersensitivity_rea | 1.79357761 |
| 33 | MP0010155_abnormal_intestine_physiology | 1.77775278 |
| 34 | MP0003693_abnormal_embryo_hatching | 1.76802723 |
| 35 | MP0001853_heart_inflammation | 1.66321167 |
| 36 | MP0002722_abnormal_immune_system | 1.63271358 |
| 37 | MP0002138_abnormal_hepatobiliary_system | 1.63261228 |
| 38 | MP0002429_abnormal_blood_cell | 1.60974567 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.53667100 |
| 40 | MP0002396_abnormal_hematopoietic_system | 1.52479973 |
| 41 | MP0001845_abnormal_inflammatory_respons | 1.46566471 |
| 42 | MP0005451_abnormal_body_composition | 1.36790799 |
| 43 | MP0004957_abnormal_blastocyst_morpholog | 1.34396688 |
| 44 | MP0001216_abnormal_epidermal_layer | 1.33236993 |
| 45 | MP0001727_abnormal_embryo_implantation | 1.29321750 |
| 46 | MP0004510_myositis | 1.29094181 |
| 47 | MP0001851_eye_inflammation | 1.23380516 |
| 48 | MP0000490_abnormal_crypts_of | 1.22381337 |
| 49 | MP0003453_abnormal_keratinocyte_physiol | 1.21182730 |
| 50 | MP0003448_altered_tumor_morphology | 1.17485993 |
| 51 | MP0001348_abnormal_lacrimal_gland | 1.13813758 |
| 52 | MP0010234_abnormal_vibrissa_follicle | 1.12437336 |
| 53 | MP0002796_impaired_skin_barrier | 1.10119699 |
| 54 | MP0010094_abnormal_chromosome_stability | 1.08603359 |
| 55 | MP0002419_abnormal_innate_immunity | 1.08455808 |
| 56 | MP0004808_abnormal_hematopoietic_stem | 1.07940295 |
| 57 | MP0003111_abnormal_nucleus_morphology | 1.04588663 |
| 58 | MP0000569_abnormal_digit_pigmentation | 1.02817662 |
| 59 | MP0004185_abnormal_adipocyte_glucose | 1.00778656 |
| 60 | MP0002019_abnormal_tumor_incidence | 0.98120110 |
| 61 | MP0002163_abnormal_gland_morphology | 0.98043643 |
| 62 | MP0003077_abnormal_cell_cycle | 0.97360246 |
| 63 | MP0003315_abnormal_perineum_morphology | 0.95768026 |
| 64 | MP0002277_abnormal_respiratory_mucosa | 0.94034740 |
| 65 | MP0010352_gastrointestinal_tract_polyps | 0.93369916 |
| 66 | MP0003303_peritoneal_inflammation | 0.92976762 |
| 67 | MP0003786_premature_aging | 0.90463744 |
| 68 | MP0008058_abnormal_DNA_repair | 0.88047409 |
| 69 | MP0008469_abnormal_protein_level | 0.86607260 |
| 70 | MP0006082_CNS_inflammation | 0.84680334 |
| 71 | MP0001533_abnormal_skeleton_physiology | 0.79995178 |
| 72 | MP0002060_abnormal_skin_morphology | 0.78534932 |
| 73 | MP0000579_abnormal_nail_morphology | 0.75272515 |
| 74 | MP0001881_abnormal_mammary_gland | 0.75247413 |
| 75 | MP0009763_increased_sensitivity_to | 0.73338864 |
| 76 | MP0005166_decreased_susceptibility_to | 0.72568129 |
| 77 | MP0000627_abnormal_mammary_gland | 0.72062563 |
| 78 | MP0001663_abnormal_digestive_system | 0.72052930 |
| 79 | MP0000858_altered_metastatic_potential | 0.71604371 |
| 80 | MP0005501_abnormal_skin_physiology | 0.71210956 |
| 81 | MP0008007_abnormal_cellular_replicative | 0.70357491 |
| 82 | MP0000350_abnormal_cell_proliferation | 0.69475837 |
| 83 | MP0002933_joint_inflammation | 0.68043675 |
| 84 | MP0005075_abnormal_melanosome_morpholog | 0.67063015 |
| 85 | MP0000371_diluted_coat_color | 0.65837722 |
| 86 | MP0001501_abnormal_sleep_pattern | 0.65815978 |
| 87 | MP0000367_abnormal_coat/_hair | 0.65108047 |
| 88 | MP0009931_abnormal_skin_appearance | 0.64225696 |
| 89 | MP0000477_abnormal_intestine_morphology | 0.62614542 |
| 90 | MP0004264_abnormal_extraembryonic_tissu | 0.62371021 |
| 91 | MP0001919_abnormal_reproductive_system | 0.61190423 |
| 92 | MP0005023_abnormal_wound_healing | 0.60299131 |
| 93 | MP0005464_abnormal_platelet_physiology | 0.60057849 |
| 94 | MP0000465_gastrointestinal_hemorrhage | 0.59317243 |
| 95 | MP0001958_emphysema | 0.59191186 |
| 96 | MP0005076_abnormal_cell_differentiation | 0.58552807 |
| 97 | MP0002168_other_aberrant_phenotype | 0.58069398 |
| 98 | MP0002254_reproductive_system_inflammat | 0.57262892 |
| 99 | MP0005379_endocrine/exocrine_gland_phen | 0.55807829 |
| 100 | MP0009765_abnormal_xenobiotic_induced | 0.54128970 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 6.43324323 |
| 2 | Abnormality of T cell number (HP:0011839) | 5.92175848 |
| 3 | Autoimmune hemolytic anemia (HP:0001890) | 5.53199422 |
| 4 | Chronic diarrhea (HP:0002028) | 5.06925461 |
| 5 | Abnormality of T cells (HP:0002843) | 4.95087279 |
| 6 | Milia (HP:0001056) | 4.78665696 |
| 7 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.42414532 |
| 8 | Retrobulbar optic neuritis (HP:0100654) | 4.39486788 |
| 9 | Optic neuritis (HP:0100653) | 4.39486788 |
| 10 | Recurrent viral infections (HP:0004429) | 4.36217768 |
| 11 | Onycholysis (HP:0001806) | 4.07201450 |
| 12 | Myositis (HP:0100614) | 3.97242494 |
| 13 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.95353274 |
| 14 | Keratoconjunctivitis sicca (HP:0001097) | 3.86290523 |
| 15 | IgA deficiency (HP:0002720) | 3.85348417 |
| 16 | Abnormality of T cell physiology (HP:0011840) | 3.81840466 |
| 17 | Orchitis (HP:0100796) | 3.78741796 |
| 18 | Pulmonary infiltrates (HP:0002113) | 3.69509598 |
| 19 | IgM deficiency (HP:0002850) | 3.64012019 |
| 20 | Recurrent fungal infections (HP:0002841) | 3.59016455 |
| 21 | Stomatitis (HP:0010280) | 3.53310790 |
| 22 | Keratoconjunctivitis (HP:0001096) | 3.47819049 |
| 23 | Oral leukoplakia (HP:0002745) | 3.34365931 |
| 24 | Duplicated collecting system (HP:0000081) | 3.26341620 |
| 25 | Fragile nails (HP:0001808) | 3.25662628 |
| 26 | Encephalitis (HP:0002383) | 3.18130110 |
| 27 | Upper limb muscle weakness (HP:0003484) | 3.15587353 |
| 28 | Plantar hyperkeratosis (HP:0007556) | 3.15047044 |
| 29 | Increased IgM level (HP:0003496) | 3.13625270 |
| 30 | Recurrent bronchitis (HP:0002837) | 3.10282283 |
| 31 | IgG deficiency (HP:0004315) | 2.95879140 |
| 32 | Joint swelling (HP:0001386) | 2.94924632 |
| 33 | Severe combined immunodeficiency (HP:0004430) | 2.94743707 |
| 34 | Aplastic anemia (HP:0001915) | 2.94236734 |
| 35 | Abnormal blistering of the skin (HP:0008066) | 2.87828754 |
| 36 | Granulocytopenia (HP:0001913) | 2.85053391 |
| 37 | Peripheral hypomyelination (HP:0007182) | 2.83848297 |
| 38 | Nail dystrophy (HP:0008404) | 2.79641752 |
| 39 | Vasculitis (HP:0002633) | 2.78560961 |
| 40 | Abnormality of nail color (HP:0100643) | 2.76627292 |
| 41 | Gangrene (HP:0100758) | 2.75757710 |
| 42 | Pustule (HP:0200039) | 2.74696387 |
| 43 | Abnormality of the renal collecting system (HP:0004742) | 2.74259182 |
| 44 | Recurrent cutaneous fungal infections (HP:0011370) | 2.73642480 |
| 45 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.73642480 |
| 46 | Eosinophilia (HP:0001880) | 2.64136160 |
| 47 | Nasal polyposis (HP:0100582) | 2.63294975 |
| 48 | B lymphocytopenia (HP:0010976) | 2.62664373 |
| 49 | Increased IgE level (HP:0003212) | 2.61362300 |
| 50 | Thick nail (HP:0001805) | 2.60870992 |
| 51 | Abnormality of eosinophils (HP:0001879) | 2.56857795 |
| 52 | Ureteral stenosis (HP:0000071) | 2.55241156 |
| 53 | Lymphoma (HP:0002665) | 2.54316947 |
| 54 | Ridged nail (HP:0001807) | 2.51837558 |
| 55 | Gastrointestinal infarctions (HP:0005244) | 2.49781836 |
| 56 | Chronic otitis media (HP:0000389) | 2.47367460 |
| 57 | Panhypogammaglobulinemia (HP:0003139) | 2.46642939 |
| 58 | Rough bone trabeculation (HP:0100670) | 2.41545211 |
| 59 | Hemoptysis (HP:0002105) | 2.40499583 |
| 60 | Combined immunodeficiency (HP:0005387) | 2.40239807 |
| 61 | Meningitis (HP:0001287) | 2.39898500 |
| 62 | Keratitis (HP:0000491) | 2.38810174 |
| 63 | Ureteral obstruction (HP:0006000) | 2.36895510 |
| 64 | Abnormality of B cell number (HP:0010975) | 2.34872049 |
| 65 | Villous atrophy (HP:0011473) | 2.30944228 |
| 66 | Abnormality of small intestinal villus morphology (HP:0011472) | 2.30944228 |
| 67 | Ileus (HP:0002595) | 2.24961265 |
| 68 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.23880222 |
| 69 | Lymphopenia (HP:0001888) | 2.15738243 |
| 70 | Hypergammaglobulinemia (HP:0010702) | 2.14918693 |
| 71 | Acute hepatic failure (HP:0006554) | 2.13344242 |
| 72 | Arterial thrombosis (HP:0004420) | 2.12979729 |
| 73 | Abnormality of the fingertips (HP:0001211) | 2.12879182 |
| 74 | Anhidrosis (HP:0000970) | 2.03475865 |
| 75 | Selective tooth agenesis (HP:0001592) | 2.01236572 |
| 76 | Poikiloderma (HP:0001029) | 2.00584159 |
| 77 | Atrophic scars (HP:0001075) | 1.98867028 |
| 78 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.98430491 |
| 79 | Abnormality of oral frenula (HP:0000190) | 1.98065932 |
| 80 | Glomerulopathy (HP:0100820) | 1.97627422 |
| 81 | Abnormality of the nasal mucosa (HP:0000433) | 1.97336194 |
| 82 | Ureteral duplication (HP:0000073) | 1.94857246 |
| 83 | Palmoplantar hyperkeratosis (HP:0000972) | 1.94617567 |
| 84 | Pulmonary embolism (HP:0002204) | 1.91522915 |
| 85 | Premature graying of hair (HP:0002216) | 1.91055646 |
| 86 | Hypoplasia of the thymus (HP:0000778) | 1.90964728 |
| 87 | Abnormality of the preputium (HP:0100587) | 1.89963633 |
| 88 | Sparse scalp hair (HP:0002209) | 1.89158009 |
| 89 | Skin ulcer (HP:0200042) | 1.88437843 |
| 90 | Alopecia of scalp (HP:0002293) | 1.87050893 |
| 91 | Pancytopenia (HP:0001876) | 1.86367485 |
| 92 | Abnormal trabecular bone morphology (HP:0100671) | 1.86262269 |
| 93 | Mediastinal lymphadenopathy (HP:0100721) | 1.84235739 |
| 94 | Abnormality of DNA repair (HP:0003254) | 1.82903134 |
| 95 | Generalized hypopigmentation of hair (HP:0011358) | 1.82018159 |
| 96 | Gastrointestinal dysmotility (HP:0002579) | 1.81427960 |
| 97 | Palmar hyperkeratosis (HP:0010765) | 1.80353329 |
| 98 | Prominent nose (HP:0000448) | 1.79922466 |
| 99 | Erythema (HP:0010783) | 1.79514380 |
| 100 | Interstitial pulmonary disease (HP:0006530) | 1.77881656 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.57105700 |
| 2 | MAP4K1 | 4.59520942 |
| 3 | FGFR4 | 3.76396773 |
| 4 | TSSK6 | 3.24184813 |
| 5 | MAP3K13 | 3.09657130 |
| 6 | PRPF4B | 3.06674711 |
| 7 | MAP3K14 | 2.97101566 |
| 8 | ITK | 2.61004823 |
| 9 | JAK3 | 2.53537736 |
| 10 | MST4 | 2.40140382 |
| 11 | EPHA3 | 2.28667574 |
| 12 | SMG1 | 2.03454316 |
| 13 | TAOK2 | 1.94049214 |
| 14 | FGFR3 | 1.84180758 |
| 15 | JAK1 | 1.76537143 |
| 16 | NME1 | 1.64266196 |
| 17 | EIF2AK1 | 1.61208461 |
| 18 | EPHB1 | 1.59254861 |
| 19 | IKBKE | 1.57820815 |
| 20 | TYK2 | 1.56146739 |
| 21 | NLK | 1.55989990 |
| 22 | CDK12 | 1.47919700 |
| 23 | SCYL2 | 1.47737114 |
| 24 | BUB1 | 1.43737424 |
| 25 | MAP3K9 | 1.43350035 |
| 26 | NME2 | 1.41661080 |
| 27 | LCK | 1.37592281 |
| 28 | SRPK1 | 1.37207501 |
| 29 | STK24 | 1.31056971 |
| 30 | MAPK11 | 1.29070675 |
| 31 | EIF2AK3 | 1.25515095 |
| 32 | ALK | 1.25443661 |
| 33 | PASK | 1.22541973 |
| 34 | FES | 1.16276071 |
| 35 | MAP3K12 | 1.15808665 |
| 36 | PRKCQ | 1.12485584 |
| 37 | ZAP70 | 1.10848665 |
| 38 | IKBKB | 1.08898863 |
| 39 | TRIB3 | 1.06872949 |
| 40 | BTK | 1.06425546 |
| 41 | ARAF | 1.04709251 |
| 42 | IRAK1 | 1.04327234 |
| 43 | CLK1 | 1.01005230 |
| 44 | WNK1 | 0.90169115 |
| 45 | MAP3K7 | 0.90159538 |
| 46 | KDR | 0.81464479 |
| 47 | IRAK3 | 0.79434245 |
| 48 | CAMKK2 | 0.78917811 |
| 49 | NEK1 | 0.78350873 |
| 50 | MAP3K8 | 0.77504156 |
| 51 | MAP3K3 | 0.75936373 |
| 52 | RIPK4 | 0.74988194 |
| 53 | CSK | 0.74226698 |
| 54 | TYRO3 | 0.73798622 |
| 55 | MAP2K6 | 0.68636321 |
| 56 | MAP3K1 | 0.67850587 |
| 57 | HIPK2 | 0.67608878 |
| 58 | JAK2 | 0.67555988 |
| 59 | SYK | 0.64921773 |
| 60 | CHUK | 0.63855143 |
| 61 | RPS6KA4 | 0.63269635 |
| 62 | TAF1 | 0.62985068 |
| 63 | EIF2AK2 | 0.62580460 |
| 64 | RPS6KA5 | 0.61549813 |
| 65 | SIK3 | 0.61223836 |
| 66 | MAP3K11 | 0.60914357 |
| 67 | STK10 | 0.60436101 |
| 68 | NEK9 | 0.59855967 |
| 69 | WNK4 | 0.58554664 |
| 70 | TAOK3 | 0.58083290 |
| 71 | TBK1 | 0.57934230 |
| 72 | HCK | 0.57877013 |
| 73 | CDK4 | 0.57082854 |
| 74 | PIK3CG | 0.56409823 |
| 75 | ILK | 0.54978340 |
| 76 | MST1R | 0.53188520 |
| 77 | VRK2 | 0.52357403 |
| 78 | TAOK1 | 0.50675651 |
| 79 | CDK7 | 0.46573383 |
| 80 | TEC | 0.45418682 |
| 81 | PKN2 | 0.44683432 |
| 82 | CHEK1 | 0.43992384 |
| 83 | CDK8 | 0.43588930 |
| 84 | STK39 | 0.42006171 |
| 85 | CDC7 | 0.41257196 |
| 86 | NTRK1 | 0.41111074 |
| 87 | PDGFRB | 0.39624844 |
| 88 | RAF1 | 0.39523919 |
| 89 | BRD4 | 0.39197854 |
| 90 | DAPK1 | 0.36840605 |
| 91 | CAMKK1 | 0.34876419 |
| 92 | PRKCH | 0.34486175 |
| 93 | MAP2K3 | 0.34300426 |
| 94 | RET | 0.33519296 |
| 95 | FGFR1 | 0.33012030 |
| 96 | ATR | 0.32517292 |
| 97 | TRPM7 | 0.31790387 |
| 98 | IRAK4 | 0.30702230 |
| 99 | SIK1 | 0.30689912 |
| 100 | NUAK1 | 0.27625243 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.88049644 |
| 2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.59712338 |
| 3 | Measles_Homo sapiens_hsa05162 | 3.19590471 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.02229021 |
| 5 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.88340773 |
| 6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.83719335 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.78043859 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.74740120 |
| 9 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 2.58532075 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.41535163 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.41021590 |
| 12 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.33668789 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.24719756 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.11775864 |
| 15 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.96545381 |
| 16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.94286535 |
| 17 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.85037411 |
| 18 | DNA replication_Homo sapiens_hsa03030 | 1.81385148 |
| 19 | Asthma_Homo sapiens_hsa05310 | 1.80016319 |
| 20 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.77325802 |
| 21 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.64046992 |
| 22 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.61871342 |
| 23 | Spliceosome_Homo sapiens_hsa03040 | 1.59001357 |
| 24 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.52161462 |
| 25 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.50227562 |
| 26 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.47735601 |
| 27 | Hepatitis B_Homo sapiens_hsa05161 | 1.39574623 |
| 28 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.35474502 |
| 29 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.35386913 |
| 30 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.27171914 |
| 31 | Apoptosis_Homo sapiens_hsa04210 | 1.27141409 |
| 32 | RNA polymerase_Homo sapiens_hsa03020 | 1.24172118 |
| 33 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.15461843 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.14811612 |
| 35 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.13864871 |
| 36 | HTLV-I infection_Homo sapiens_hsa05166 | 1.12722145 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 1.12101895 |
| 38 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.11150031 |
| 39 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.08052621 |
| 40 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.06458560 |
| 41 | Influenza A_Homo sapiens_hsa05164 | 1.06291660 |
| 42 | RNA transport_Homo sapiens_hsa03013 | 1.03059673 |
| 43 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.99969214 |
| 44 | Shigellosis_Homo sapiens_hsa05131 | 0.99395028 |
| 45 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.97421518 |
| 46 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.95925748 |
| 47 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.94562094 |
| 48 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.92868868 |
| 49 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.92760377 |
| 50 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.87355277 |
| 51 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.86244909 |
| 52 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.85358302 |
| 53 | Viral myocarditis_Homo sapiens_hsa05416 | 0.83219006 |
| 54 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.78794818 |
| 55 | Hepatitis C_Homo sapiens_hsa05160 | 0.78195864 |
| 56 | Salmonella infection_Homo sapiens_hsa05132 | 0.76825208 |
| 57 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.74254420 |
| 58 | Protein export_Homo sapiens_hsa03060 | 0.71312843 |
| 59 | Ribosome_Homo sapiens_hsa03010 | 0.71031291 |
| 60 | Thyroid cancer_Homo sapiens_hsa05216 | 0.70840687 |
| 61 | RNA degradation_Homo sapiens_hsa03018 | 0.69970502 |
| 62 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.65589873 |
| 63 | Cell cycle_Homo sapiens_hsa04110 | 0.63634411 |
| 64 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.63163546 |
| 65 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.60547566 |
| 66 | Base excision repair_Homo sapiens_hsa03410 | 0.58242770 |
| 67 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.57516642 |
| 68 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.56816600 |
| 69 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.51130645 |
| 70 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.51064296 |
| 71 | Legionellosis_Homo sapiens_hsa05134 | 0.50726881 |
| 72 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.48630086 |
| 73 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.47262882 |
| 74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.46974912 |
| 75 | Prion diseases_Homo sapiens_hsa05020 | 0.46815831 |
| 76 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.45297661 |
| 77 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.42141097 |
| 78 | Insulin resistance_Homo sapiens_hsa04931 | 0.39969571 |
| 79 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.39420565 |
| 80 | Homologous recombination_Homo sapiens_hsa03440 | 0.37938884 |
| 81 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.37800739 |
| 82 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.37356952 |
| 83 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.36611924 |
| 84 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.36100465 |
| 85 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.33376687 |
| 86 | Prostate cancer_Homo sapiens_hsa05215 | 0.33033859 |
| 87 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.31393523 |
| 88 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.30430664 |
| 89 | Colorectal cancer_Homo sapiens_hsa05210 | 0.30328750 |
| 90 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.29054698 |
| 91 | Leishmaniasis_Homo sapiens_hsa05140 | 0.28152705 |
| 92 | Purine metabolism_Homo sapiens_hsa00230 | 0.27987152 |
| 93 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26252909 |
| 94 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.25774943 |
| 95 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.23778955 |
| 96 | Endocytosis_Homo sapiens_hsa04144 | 0.22770200 |
| 97 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.22761356 |
| 98 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.20710370 |
| 99 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.20235932 |
| 100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.20085099 |

