ZBP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)7.32216532
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)7.32216532
3antigen processing and presentation of endogenous antigen (GO:0019883)6.79165332
4response to type I interferon (GO:0034340)5.76959537
5type I interferon signaling pathway (GO:0060337)5.75703010
6cellular response to type I interferon (GO:0071357)5.75703010
7antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.46789780
8positive regulation of interferon-alpha production (GO:0032727)5.03676241
9positive regulation of gamma-delta T cell activation (GO:0046645)4.83061582
10regulation of interferon-alpha production (GO:0032647)4.82604273
11detection of other organism (GO:0098543)4.54252209
12response to interleukin-15 (GO:0070672)4.51309378
13interferon-gamma-mediated signaling pathway (GO:0060333)4.49740874
14immunoglobulin mediated immune response (GO:0016064)4.48249992
15cellular response to interleukin-15 (GO:0071350)4.38973421
16detection of bacterium (GO:0016045)4.38377806
17negative regulation of lymphocyte mediated immunity (GO:0002707)4.37078279
18positive regulation by symbiont of host defense response (GO:0052509)4.33102454
19modulation by symbiont of host defense response (GO:0052031)4.33102454
20modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.33102454
21modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.33102454
22positive regulation by organism of defense response of other organism involved in symbiotic interact4.33102454
23modulation by symbiont of host immune response (GO:0052553)4.33102454
24T cell migration (GO:0072678)4.22474737
25response to interferon-alpha (GO:0035455)4.20199516
26negative regulation of interleukin-12 production (GO:0032695)4.12636581
27regulation of interleukin-12 biosynthetic process (GO:0045075)4.04231347
28activated T cell proliferation (GO:0050798)4.02809449
29cellular response to interferon-beta (GO:0035458)4.00679956
30negative regulation of T cell mediated immunity (GO:0002710)4.00346113
31cellular extravasation (GO:0045123)3.91121880
32negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.90414946
33leukocyte migration involved in inflammatory response (GO:0002523)3.89051177
34negative regulation of viral genome replication (GO:0045071)3.88662799
35detection of external biotic stimulus (GO:0098581)3.87192844
36microglial cell activation (GO:0001774)3.81845611
37response to interferon-beta (GO:0035456)3.80964278
38regulation of interferon-beta biosynthetic process (GO:0045357)3.78586789
39* regulation of type I interferon-mediated signaling pathway (GO:0060338)3.78424045
40negative regulation of leukocyte mediated immunity (GO:0002704)3.75984723
41detection of molecule of bacterial origin (GO:0032490)3.73499531
42* positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.72396871
43positive regulation of antigen processing and presentation (GO:0002579)3.70155595
44neutrophil activation involved in immune response (GO:0002283)3.68539934
45positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.67458429
46positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.64683548
47negative thymic T cell selection (GO:0045060)3.64284549
48positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.62776189
49cellular response to interferon-gamma (GO:0071346)3.62415080
50negative T cell selection (GO:0043383)3.62242218
51regulation of RIG-I signaling pathway (GO:0039535)3.62166995
52positive regulation of interferon-beta production (GO:0032728)3.57458184
53cellular response to virus (GO:0098586)3.55593139
54regulation of T cell mediated cytotoxicity (GO:0001914)3.55105398
55response to peptidoglycan (GO:0032494)3.54974319
56defense response to protozoan (GO:0042832)3.53320277
57leukocyte aggregation (GO:0070486)3.51979846
58positive regulation of T cell mediated cytotoxicity (GO:0001916)3.51974336
59B cell mediated immunity (GO:0019724)3.50820420
60regulation of B cell receptor signaling pathway (GO:0050855)3.50621038
61regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.48318441
62B cell receptor signaling pathway (GO:0050853)3.46699161
63regulation of alpha-beta T cell proliferation (GO:0046640)3.45133285
64JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.44986121
65regulation of response to interferon-gamma (GO:0060330)3.44125210
66positive regulation of humoral immune response (GO:0002922)3.43919338
67regulation of gamma-delta T cell activation (GO:0046643)3.43565762
68cellular response to interferon-alpha (GO:0035457)3.42848839
69regulation of gamma-delta T cell differentiation (GO:0045586)3.41557084
70lipopolysaccharide-mediated signaling pathway (GO:0031663)3.41367259
71tolerance induction (GO:0002507)3.41285387
72NIK/NF-kappaB signaling (GO:0038061)3.39993446
73detection of biotic stimulus (GO:0009595)3.38609886
74negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.38593536
75negative regulation of cell killing (GO:0031342)3.38593536
76regulation of regulatory T cell differentiation (GO:0045589)3.38197863
77production of molecular mediator involved in inflammatory response (GO:0002532)3.37286937
78negative regulation of T-helper cell differentiation (GO:0045623)3.37275449
79negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.37275449
80regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.36648512
81antigen processing and presentation via MHC class Ib (GO:0002475)3.35266001
82neutrophil mediated immunity (GO:0002446)3.34548617
83T-helper 1 type immune response (GO:0042088)3.33038830
84myeloid cell activation involved in immune response (GO:0002275)3.32630198
85regulation of T-helper 1 cell differentiation (GO:0045625)3.31771326
86regulation of B cell differentiation (GO:0045577)3.31513019
87positive regulation of natural killer cell differentiation (GO:0032825)3.31182997
88myeloid dendritic cell differentiation (GO:0043011)3.29731613
89regulation of antigen processing and presentation (GO:0002577)3.29397902
90respiratory burst (GO:0045730)3.29382566
91response to protozoan (GO:0001562)3.27655569
92regulation of dendritic cell antigen processing and presentation (GO:0002604)3.24218894
93negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.23974394
94macrophage activation (GO:0042116)3.23472864
95interferon-gamma production (GO:0032609)3.23295525
96dendritic cell migration (GO:0036336)3.22087675
97negative regulation of innate immune response (GO:0045824)3.20600190
98response to interferon-gamma (GO:0034341)3.18761562
99myeloid dendritic cell activation (GO:0001773)3.18756886
100response to host immune response (GO:0052572)3.18070093
101response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.18070093
102dendritic cell chemotaxis (GO:0002407)3.18051909
103cellular response to exogenous dsRNA (GO:0071360)3.16505112
104regulation of T cell tolerance induction (GO:0002664)3.14830177
105positive regulation of interleukin-12 production (GO:0032735)3.14727017
106regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.14476614
107positive regulation of chemokine biosynthetic process (GO:0045080)3.14083072
108interferon-gamma secretion (GO:0072643)3.12732768
109positive regulation of alpha-beta T cell proliferation (GO:0046641)3.11763213
110positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.11026047
111regulation of natural killer cell mediated immunity (GO:0002715)3.10720597
112regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.10720597
113negative regulation of alpha-beta T cell activation (GO:0046636)3.09802264
114positive thymic T cell selection (GO:0045059)3.09747781
115regulation of tolerance induction (GO:0002643)3.06263863
116myeloid leukocyte mediated immunity (GO:0002444)3.05184847
117defense response to virus (GO:0051607)3.03099568
118macrophage activation involved in immune response (GO:0002281)3.02200654
119granulocyte activation (GO:0036230)3.00559519
120positive regulation of B cell mediated immunity (GO:0002714)3.00395225
121positive regulation of immunoglobulin mediated immune response (GO:0002891)3.00395225
122negative regulation of adaptive immune response (GO:0002820)2.99972339
123natural killer cell mediated cytotoxicity (GO:0042267)2.98878617
124natural killer cell mediated immunity (GO:0002228)2.98878617
125positive regulation of B cell differentiation (GO:0045579)2.98753559
126leukocyte degranulation (GO:0043299)2.98135198
127lymphocyte chemotaxis (GO:0048247)2.97096653
128positive regulation of toll-like receptor signaling pathway (GO:0034123)2.96989421
129regulation of mast cell activation (GO:0033003)2.96961004
130cytidine metabolic process (GO:0046087)2.96074170
131cytidine catabolic process (GO:0006216)2.96074170
132cytidine deamination (GO:0009972)2.96074170
133positive T cell selection (GO:0043368)2.95991241
134positive regulation of interleukin-17 production (GO:0032740)2.94695503
135regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.93316239
136neutrophil activation (GO:0042119)2.92686598
137negative regulation of myeloid cell apoptotic process (GO:0033033)2.88809123
138positive regulation of cytokine biosynthetic process (GO:0042108)2.88540336
139thymic T cell selection (GO:0045061)2.88361096
140regulation of hypersensitivity (GO:0002883)2.88153721
141T cell selection (GO:0045058)2.87293588
142response to muramyl dipeptide (GO:0032495)2.86908433
143response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.86812904
144response to host (GO:0075136)2.86812904
145response to host defenses (GO:0052200)2.86812904
146positive regulation of interferon-gamma biosynthetic process (GO:0045078)2.86246728
147positive regulation of isotype switching (GO:0045830)2.84666622
148regulation of isotype switching to IgG isotypes (GO:0048302)2.84478108

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human7.70989140
2IRF8_21731497_ChIP-ChIP_J774_Mouse6.13223325
3* IRF1_21803131_ChIP-Seq_MONOCYTES_Human5.90088631
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.30082788
5* IRF8_22096565_ChIP-ChIP_GC-B_Mouse5.08648171
6BP1_19119308_ChIP-ChIP_Hs578T_Human3.89425196
7* STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.84202742
8IRF8_27001747_Chip-Seq_BMDM_Mouse3.72595759
9* STAT4_19710469_ChIP-ChIP_TH1__Mouse3.33964353
10STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.29097308
11SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.22440699
12NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.16017511
13MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.04222870
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.80876377
15RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.78006752
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.49278766
17MYB_21317192_ChIP-Seq_ERMYB_Mouse2.46817341
18* MYB_26560356_Chip-Seq_TH2_Human2.30822554
19RUNX_20019798_ChIP-Seq_JUKART_Human2.26274203
20NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.26273722
21MAF_26560356_Chip-Seq_TH1_Human2.20847611
22FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.17596835
23Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.06788409
24BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.98391985
25MYB_26560356_Chip-Seq_TH1_Human1.97092077
26* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.94120523
27NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.93837405
28SPI1_23547873_ChIP-Seq_NB4_Human1.88969356
29BRD4_27068464_Chip-Seq_AML-cells_Mouse1.88148413
30RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.81007729
31STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.72326733
32RUNX1_22412390_ChIP-Seq_EML_Mouse1.71559715
33UTX_26944678_Chip-Seq_JUKART_Human1.66231033
34VDR_21846776_ChIP-Seq_THP-1_Human1.65090576
35MYC_22102868_ChIP-Seq_BL_Human1.62461204
36VDR_24763502_ChIP-Seq_THP-1_Human1.62336239
37SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53973735
38ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.52205478
39CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.51061027
40PU_27001747_Chip-Seq_BMDM_Mouse1.50834751
41CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.47037940
42GATA3_27048872_Chip-Seq_THYMUS_Human1.46771237
43PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.45523082
44CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.42396688
45SPI1_23127762_ChIP-Seq_K562_Human1.41411800
46* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.39639836
47* MAF_26560356_Chip-Seq_TH2_Human1.38408570
48VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.37230384
49SCL_19346495_ChIP-Seq_HPC-7_Human1.37055838
50* THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.35863181
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.32967393
52GATA1_22025678_ChIP-Seq_K562_Human1.29603879
53TP63_17297297_ChIP-ChIP_HaCaT_Human1.27962835
54ELF1_17652178_ChIP-ChIP_JURKAT_Human1.26438828
55MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.26082724
56TCF7_22412390_ChIP-Seq_EML_Mouse1.24203573
57VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.24147699
58* RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.22975112
59CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.21083181
60* GATA2_22383799_ChIP-Seq_G1ME_Mouse1.20310025
61* GATA3_26560356_Chip-Seq_TH2_Human1.19172197
62EGR1_23403033_ChIP-Seq_LIVER_Mouse1.17367392
63GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12789878
64CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.10132871
65ELK3_25401928_ChIP-Seq_HUVEC_Human1.09608311
66SMRT_27268052_Chip-Seq_Bcells_Human1.09207711
67* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07251191
68EGR1_19032775_ChIP-ChIP_M12_Human1.06996489
69LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.06566534
70PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.05310885
71ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.05226432
72PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05094976
73VDR_24787735_ChIP-Seq_THP-1_Human1.05083151
74SMAD_19615063_ChIP-ChIP_OVARY_Human1.04582881
75PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04327858
76SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01423765
77* PPARA_22158963_ChIP-Seq_LIVER_Mouse0.99416908
78GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.98995397
79SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.98039556
80SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97087078
81KDM2B_26808549_Chip-Seq_DND41_Human0.96772690
82IKZF1_21737484_ChIP-ChIP_HCT116_Human0.94311188
83GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92885379
84KDM2B_26808549_Chip-Seq_SUP-B15_Human0.91158174
85RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.90905781
86* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.90899713
87NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.89539397
88GATA3_26560356_Chip-Seq_TH1_Human0.87373961
89GATA2_21666600_ChIP-Seq_HMVEC_Human0.86609128
90RXR_22158963_ChIP-Seq_LIVER_Mouse0.86122358
91GATA1_22383799_ChIP-Seq_G1ME_Mouse0.86121362
92PU.1_20513432_ChIP-Seq_Bcells_Mouse0.85762259
93CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.85369595
94TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.82730748
95LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.82188429
96TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.81957772
97GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.80316322
98FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.80191470
99SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.79467865
100NOTCH1_21737748_ChIP-Seq_TLL_Human0.79291581
101DROSHA_22980978_ChIP-Seq_HELA_Human0.77968019
102GATA1_19941827_ChIP-Seq_MEL_Mouse0.77963929
103TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.77783161
104GATA1_19941826_ChIP-Seq_K562_Human0.77600715
105PRDM14_20953172_ChIP-Seq_ESCs_Human0.75899900
106FLI1_27457419_Chip-Seq_LIVER_Mouse0.75735098
107ZNF274_21170338_ChIP-Seq_K562_Hela0.74540909
108LXR_22158963_ChIP-Seq_LIVER_Mouse0.73261414
109BCOR_27268052_Chip-Seq_Bcells_Human0.72319512
110* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.71865081
111CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.70097805
112NANOG_20526341_ChIP-Seq_ESCs_Human0.69918037
113EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.69459574
114LXR_22292898_ChIP-Seq_THP-1_Human0.69178913
115TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.67249442
116GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.66488206
117SPI1_20517297_ChIP-Seq_HL60_Human0.65825270
118* CTCF_26484167_Chip-Seq_Bcells_Mouse0.64757250
119BCL6_27268052_Chip-Seq_Bcells_Human0.62175421
120GATA2_19941826_ChIP-Seq_K562_Human0.62085848
121SOX2_20726797_ChIP-Seq_SW620_Human0.61880906
122FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.60455080
123FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.59374229
124NCOR1_26117541_ChIP-Seq_K562_Human0.58377964
125P300_27268052_Chip-Seq_Bcells_Human0.58263616

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.81737910
2MP0009785_altered_susceptibility_to4.00521211
3MP0005671_abnormal_response_to3.52689806
4MP0003436_decreased_susceptibility_to3.45842139
5MP0000685_abnormal_immune_system3.40376145
6MP0005387_immune_system_phenotype3.28204647
7MP0001790_abnormal_immune_system3.28204647
8MP0005000_abnormal_immune_tolerance3.18159168
9MP0003724_increased_susceptibility_to3.16645534
10MP0006082_CNS_inflammation3.15840461
11MP0005025_abnormal_response_to3.12407122
12MP0002148_abnormal_hypersensitivity_rea3.08187506
13MP0001800_abnormal_humoral_immune2.96753347
14MP0004510_myositis2.83177299
15MP0003303_peritoneal_inflammation2.77340876
16MP0002723_abnormal_immune_serum2.74432743
17MP0002452_abnormal_antigen_presenting2.72593347
18MP0002419_abnormal_innate_immunity2.68823651
19MP0001819_abnormal_immune_cell2.48559976
20MP0002420_abnormal_adaptive_immunity2.46254492
21MP0003763_abnormal_thymus_physiology2.38701597
22MP0004947_skin_inflammation2.32531353
23MP0002166_altered_tumor_susceptibility2.28996960
24MP0002006_tumorigenesis2.14976497
25MP0010155_abnormal_intestine_physiology2.08178396
26MP0002405_respiratory_system_inflammati2.02312591
27MP0002398_abnormal_bone_marrow1.96660282
28MP0000716_abnormal_immune_system1.96085032
29MP0001845_abnormal_inflammatory_respons1.94662197
30MP0009333_abnormal_splenocyte_physiolog1.93063238
31MP0001533_abnormal_skeleton_physiology1.92445667
32MP0005464_abnormal_platelet_physiology1.87005571
33MP0001853_heart_inflammation1.83592057
34MP0008469_abnormal_protein_level1.76596895
35MP0005058_abnormal_lysosome_morphology1.74677054
36MP0005310_abnormal_salivary_gland1.73814727
37MP0003300_gastrointestinal_ulcer1.71553359
38MP0009764_decreased_sensitivity_to1.68451815
39MP0003448_altered_tumor_morphology1.62611296
40MP0000689_abnormal_spleen_morphology1.59571977
41MP0009840_abnormal_foam_cell1.57661424
42MP0002429_abnormal_blood_cell1.57038419
43MP0001873_stomach_inflammation1.56066165
44MP0002722_abnormal_immune_system1.54906285
45MP0002132_abnormal_respiratory_system1.54540685
46MP0004381_abnormal_hair_follicle1.54420152
47MP0003191_abnormal_cellular_cholesterol1.48011498
48MP0000569_abnormal_digit_pigmentation1.47872128
49MP0005075_abnormal_melanosome_morpholog1.39425700
50MP0002138_abnormal_hepatobiliary_system1.34143719
51MP0000858_altered_metastatic_potential1.29103956
52MP0000343_altered_response_to1.29103098
53MP0003787_abnormal_imprinting1.25134769
54MP0002933_joint_inflammation1.24241368
55MP0003866_abnormal_defecation1.21582505
56MP0000703_abnormal_thymus_morphology1.18755811
57MP0002998_abnormal_bone_remodeling1.18742398
58MP0003075_altered_response_to1.16938076
59MP0004883_abnormal_blood_vessel1.15363853
60MP0000604_amyloidosis1.15106538
61MP0009278_abnormal_bone_marrow1.14770278
62MP0001986_abnormal_taste_sensitivity1.13589387
63MP0003828_pulmonary_edema1.10925922
64MP0008260_abnormal_autophagy1.09439570
65MP0005397_hematopoietic_system_phenotyp1.09201597
66MP0001545_abnormal_hematopoietic_system1.09201597
67MP0003172_abnormal_lysosome_physiology1.06418297
68MP0009763_increased_sensitivity_to1.04925317
69MP0001851_eye_inflammation1.00849782
70MP0002254_reproductive_system_inflammat1.00060372
71MP0010307_abnormal_tumor_latency0.99702297
72MP0005166_decreased_susceptibility_to0.98318379
73MP0003453_abnormal_keratinocyte_physiol0.96589205
74MP0000015_abnormal_ear_pigmentation0.94681146
75MP0004782_abnormal_surfactant_physiolog0.91803360
76MP0002396_abnormal_hematopoietic_system0.89333221
77MP0010234_abnormal_vibrissa_follicle0.86099799
78MP0003045_fibrosis0.85568462
79MP0005023_abnormal_wound_healing0.83468888
80MP0004808_abnormal_hematopoietic_stem0.83385604
81MP0005390_skeleton_phenotype0.82163574
82MP0002277_abnormal_respiratory_mucosa0.80818124
83MP0003195_calcinosis0.79034620
84MP0005174_abnormal_tail_pigmentation0.78149900
85MP0003186_abnormal_redox_activity0.77951127
86MP0000465_gastrointestinal_hemorrhage0.76531831
87MP0010352_gastrointestinal_tract_polyps0.75669966
88MP0005076_abnormal_cell_differentiation0.74946200
89MP0002928_abnormal_bile_duct0.74041175
90MP0005377_hearing/vestibular/ear_phenot0.73996362
91MP0003878_abnormal_ear_physiology0.73996362
92MP0000490_abnormal_crypts_of0.73960187
93MP0000609_abnormal_liver_physiology0.73801850
94MP0008877_abnormal_DNA_methylation0.73767162
95MP0003252_abnormal_bile_duct0.70074732
96MP0002136_abnormal_kidney_physiology0.68941648
97MP0000249_abnormal_blood_vessel0.67585748
98MP0005360_urolithiasis0.65581757
99MP0003091_abnormal_cell_migration0.64439602
100MP0001881_abnormal_mammary_gland0.63944999
101MP0005164_abnormal_response_to0.63879487
102MP0001663_abnormal_digestive_system0.63420023
103MP0009765_abnormal_xenobiotic_induced0.63138210
104MP0002019_abnormal_tumor_incidence0.63135587
105MP0003806_abnormal_nucleotide_metabolis0.61915109
106MP0002653_abnormal_ependyma_morphology0.60867059
107MP0003183_abnormal_peptide_metabolism0.60634625
108MP0003566_abnormal_cell_adhesion0.59514225
109MP0003795_abnormal_bone_structure0.58228133
110MP0005083_abnormal_biliary_tract0.58040927
111MP0001348_abnormal_lacrimal_gland0.57887827
112MP0001501_abnormal_sleep_pattern0.56748561
113MP0003656_abnormal_erythrocyte_physiolo0.56431850
114MP0005319_abnormal_enzyme/_coenzyme0.55975656
115MP0002009_preneoplasia0.54441205
116MP0004130_abnormal_muscle_cell0.53856001
117MP0005451_abnormal_body_composition0.52135145
118MP0002332_abnormal_exercise_endurance0.51984545
119MP0004484_altered_response_of0.51176119
120MP0000371_diluted_coat_color0.51155445
121MP0002168_other_aberrant_phenotype0.50816508
122MP0000598_abnormal_liver_morphology0.50502705
123MP0000470_abnormal_stomach_morphology0.50103868
124MP0003690_abnormal_glial_cell0.49450233
125MP0001216_abnormal_epidermal_layer0.48730733
126MP0008873_increased_physiological_sensi0.46879661
127MP0005584_abnormal_enzyme/coenzyme_acti0.46713285
128MP0002693_abnormal_pancreas_physiology0.46073478

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)6.09030122
2Elevated erythrocyte sedimentation rate (HP:0003565)5.66849765
3Recurrent abscess formation (HP:0002722)5.56575000
4Chronic otitis media (HP:0000389)5.52604769
5Recurrent bacterial skin infections (HP:0005406)5.09025058
6Myositis (HP:0100614)4.73487534
7Nasal polyposis (HP:0100582)4.69267155
8Hypochromic microcytic anemia (HP:0004840)4.62813841
9Autoimmune thrombocytopenia (HP:0001973)4.59176134
10Recurrent gram-negative bacterial infections (HP:0005420)4.52083783
11Recurrent fungal infections (HP:0002841)4.38917598
12Recurrent bronchitis (HP:0002837)4.34245369
13Recurrent viral infections (HP:0004429)4.23389099
14Abnormality of the nasal mucosa (HP:0000433)4.18009925
15Orchitis (HP:0100796)4.16707017
16Abnormality of macrophages (HP:0004311)4.08580379
17Mediastinal lymphadenopathy (HP:0100721)4.01599562
18Vasculitis (HP:0002633)3.92981076
19Retrobulbar optic neuritis (HP:0100654)3.90438024
20Optic neuritis (HP:0100653)3.90438024
21Recurrent skin infections (HP:0001581)3.89955636
22Hypochromic anemia (HP:0001931)3.84400573
23Increased IgM level (HP:0003496)3.84397967
24Abnormality of T cell number (HP:0011839)3.82157849
25Stomatitis (HP:0010280)3.80476137
26Recurrent cutaneous fungal infections (HP:0011370)3.79097891
27Chronic mucocutaneous candidiasis (HP:0002728)3.79097891
28T lymphocytopenia (HP:0005403)3.69892505
29Pustule (HP:0200039)3.53421218
30Systemic lupus erythematosus (HP:0002725)3.52770677
31Abnormality of T cells (HP:0002843)3.28013913
32Hypergammaglobulinemia (HP:0010702)3.24053124
33Interstitial pulmonary disease (HP:0006530)3.22840902
34Chronic sinusitis (HP:0011109)3.20642615
35Gingivitis (HP:0000230)3.16708067
36Chronic obstructive pulmonary disease (HP:0006510)3.15005688
37Obstructive lung disease (HP:0006536)3.15005688
38Basal ganglia calcification (HP:0002135)3.11093240
39Autoimmune hemolytic anemia (HP:0001890)3.10492917
40Abnormal delayed hypersensitivity skin test (HP:0002963)2.98069238
41Meningitis (HP:0001287)2.97474891
42Gastrointestinal infarctions (HP:0005244)2.97425805
43Pulmonary infiltrates (HP:0002113)2.96527666
44Vacuolated lymphocytes (HP:0001922)2.90767615
45Prolonged bleeding time (HP:0003010)2.89253861
46Hemoptysis (HP:0002105)2.88844196
47Periodontitis (HP:0000704)2.82779225
48Abnormality of T cell physiology (HP:0011840)2.80914857
49Leukocytosis (HP:0001974)2.79486923
50Increased IgE level (HP:0003212)2.79110714
51Inflammation of the large intestine (HP:0002037)2.77716198
52Episodic fever (HP:0001954)2.76791968
53Spontaneous hematomas (HP:0007420)2.75649412
54Cellulitis (HP:0100658)2.75156689
55Gingival bleeding (HP:0000225)2.74464626
56IgM deficiency (HP:0002850)2.73373273
57Colitis (HP:0002583)2.71228602
58Microcytic anemia (HP:0001935)2.70842040
59Joint swelling (HP:0001386)2.66689312
60Arterial thrombosis (HP:0004420)2.62570726
61Gastrointestinal inflammation (HP:0004386)2.62005044
62Eosinophilia (HP:0001880)2.61591819
63Combined immunodeficiency (HP:0005387)2.61470780
64Lymphopenia (HP:0001888)2.58121203
65Stomach cancer (HP:0012126)2.57651856
66IgG deficiency (HP:0004315)2.56996191
67Abnormality of cells of the lymphoid lineage (HP:0012140)2.56010258
68Severe combined immunodeficiency (HP:0004430)2.53953063
69Keratoconjunctivitis sicca (HP:0001097)2.53689029
70Panhypogammaglobulinemia (HP:0003139)2.52964425
71Urticaria (HP:0001025)2.51628527
72Emphysema (HP:0002097)2.48291423
73Abnormality of the pleura (HP:0002103)2.45663065
74Abnormality of eosinophils (HP:0001879)2.44482614
75Anorexia (HP:0002039)2.41119636
76Increased cerebral lipofuscin (HP:0011813)2.39332996
77Bronchitis (HP:0012387)2.38916660
78Keratoconjunctivitis (HP:0001096)2.38338860
79Chronic diarrhea (HP:0002028)2.35263942
80Encephalitis (HP:0002383)2.35054269
81Agammaglobulinemia (HP:0004432)2.34457965
82Petechiae (HP:0000967)2.32492447
83Peritonitis (HP:0002586)2.32083565
84Skin ulcer (HP:0200042)2.28128032
85Myocardial infarction (HP:0001658)2.26339611
86Granulocytopenia (HP:0001913)2.26254254
87Loss of speech (HP:0002371)2.23957077
88Porencephaly (HP:0002132)2.23312161
89IgA deficiency (HP:0002720)2.22962109
90Gastrointestinal stroma tumor (HP:0100723)2.22412058
91Recurrent pneumonia (HP:0006532)2.22277317
92Sepsis (HP:0100806)2.19967269
93Thyroiditis (HP:0100646)2.19195765
94Recurrent lower respiratory tract infections (HP:0002783)2.16239076
95Increased neuronal autofluorescent lipopigment (HP:0002074)2.15793255
96Keratitis (HP:0000491)2.15026084
97Cheilitis (HP:0100825)2.14522998
98Purpura (HP:0000979)2.14261805
99Osteomyelitis (HP:0002754)2.14203790
100Epistaxis (HP:0000421)2.13594412
101Premature loss of primary teeth (HP:0006323)2.13236330
102Acute hepatic failure (HP:0006554)2.12574193
103Thick nail (HP:0001805)2.12461325
104Hematochezia (HP:0002573)2.11530271
105Pulmonary embolism (HP:0002204)2.08690681
106Arthralgia (HP:0002829)2.07095507
107Chest pain (HP:0100749)2.06735274
108Absent rod-and cone-mediated responses on ERG (HP:0007688)2.06509075
109Glomerulonephritis (HP:0000099)2.06428204
110Abnormality of the endocardium (HP:0004306)2.06136573
111Thrombocytosis (HP:0001894)2.05713940
112Gangrene (HP:0100758)2.05159307
113Prostate neoplasm (HP:0100787)2.03186259
114Recurrent sinusitis (HP:0011108)1.99100324
115Abnormality of B cell number (HP:0010975)1.98292080
116Abnormality of the pericardium (HP:0001697)1.96445692
117Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.92524726
118Acne (HP:0001061)1.92070960
119Abnormality of the heme biosynthetic pathway (HP:0010472)1.89374457
120Skin rash (HP:0000988)1.86471512
121Hemiplegia (HP:0002301)1.85538531
122Vertigo (HP:0002321)1.85443019
123Glomerulopathy (HP:0100820)1.84077947
124Alveolar cell carcinoma (HP:0006519)1.82725163

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TYK24.26373529
2MAP4K14.05912604
3MAP3K143.81149465
4IKBKE3.79337732
5TBK13.62148854
6JAK33.49182664
7FGFR43.43995852
8TXK3.42710579
9BLK3.00656547
10JAK12.85859328
11TNK22.58145537
12KIT2.56564362
13ERN12.36371117
14ZAP702.18243625
15FRK2.14832105
16ACVR1B2.14042321
17IRAK42.11749944
18FGFR32.07607682
19IKBKB2.04058061
20RIPK42.02509715
21MAP3K131.81901915
22CSK1.73357663
23EPHB11.69097862
24IRAK31.64426169
25SYK1.51081749
26STK101.50900281
27ITK1.47317453
28LCK1.44891188
29EPHA31.41717841
30HCK1.38439954
31CHUK1.37902556
32NME21.36743146
33GRK61.28287543
34BTK1.27833136
35PBK1.24636222
36NLK1.24605548
37PIM21.20257861
38MST41.20099068
39TAOK11.18840869
40TEC1.16177803
41JAK21.13632476
42CSF1R1.12308295
43RPS6KA41.04383873
44PTK2B1.03353768
45LYN1.02560442
46YES11.00076202
47MAP3K100.99148553
48PIM10.94396851
49MARK30.93627053
50TAOK30.91629829
51LRRK20.89808683
52KDR0.88675532
53FES0.87785089
54PIK3CG0.87650544
55PRKD20.85426507
56ADRBK20.84302705
57TGFBR20.83209544
58MAP2K60.82650374
59NEK90.79960797
60PRKCQ0.76892556
61TRIB30.75599987
62BMX0.72888571
63IRAK10.72383418
64FGR0.72147205
65CAMKK20.71606311
66MAP3K70.70716333
67STK110.70661350
68RIPK10.68342055
69PRPF4B0.65734244
70DAPK20.63538152
71MARK20.61217663
72SIK30.60795638
73PKN20.60448969
74PTK60.58218661
75MAP3K60.56774781
76OXSR10.56056913
77IRAK20.55371764
78MAPK110.53490668
79GRK70.53336067
80CDK190.53143959
81EGFR0.52993671
82SIK20.52768173
83KSR20.51900334
84PRKCH0.51241783
85PRKCD0.47198946
86TESK20.46637883
87CLK10.46078752
88MATK0.45855128
89STK380.45749328
90EIF2AK20.45723094
91STK40.45645719
92ABL10.45575814
93FLT30.43611685
94ADRBK10.43396189
95DYRK1B0.43131803
96MAP2K30.42935508
97MAPK130.41274577
98PDPK10.41118675
99MAP3K20.39999850
100MAPK70.38376852
101MAPK120.37893660
102MAP2K40.37890965
103SIK10.37533460
104MAP3K50.37278179
105PRKCZ0.36188312
106CDC42BPA0.36010054
107RPS6KA50.35854280
108TESK10.35511647
109BMPR20.35131308
110TTN0.33201656
111MST1R0.33137539
112PDK10.33074582
113TLK10.32700808
114MAP2K20.32405831
115FYN0.31785505
116PAK30.31323662
117ALK0.31035432
118MAP3K10.30922308
119CDK120.30172813
120SGK20.28598006
121INSR0.28255515
122MAP4K20.27053792
123ABL20.26534908
124MAPKAPK20.25771354
125MAP3K110.24651677
126PRKG20.24569350
127CDK40.24511622
128MAP3K30.23764604
129IGF1R0.23005321
130HIPK20.22297011
131PDGFRB0.21288895
132TGFBR10.21000691
133ARAF0.20323524
134CDK60.19675990
135MAPK40.19338043
136SRC0.18430000
137STK240.17450276
138MAPK30.17201644

Predicted pathways (KEGG)

RankGene SetZ-score
1Leishmaniasis_Homo sapiens_hsa051403.16253443
2Primary immunodeficiency_Homo sapiens_hsa053403.05156772
3Allograft rejection_Homo sapiens_hsa053302.95740267
4Graft-versus-host disease_Homo sapiens_hsa053322.93670769
5Measles_Homo sapiens_hsa051622.84734914
6NF-kappa B signaling pathway_Homo sapiens_hsa040642.77276791
7RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.76231692
8Staphylococcus aureus infection_Homo sapiens_hsa051502.73680121
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.67236734
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.63969062
11Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.61625571
12* Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.48406656
13Antigen processing and presentation_Homo sapiens_hsa046122.30673078
14Osteoclast differentiation_Homo sapiens_hsa043802.26207140
15Influenza A_Homo sapiens_hsa051642.14024625
16Legionellosis_Homo sapiens_hsa051342.09606191
17Herpes simplex infection_Homo sapiens_hsa051682.06751562
18Malaria_Homo sapiens_hsa051442.02051022
19Pertussis_Homo sapiens_hsa051331.95072907
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.91830258
21Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.91605326
22Toxoplasmosis_Homo sapiens_hsa051451.79816829
23Tuberculosis_Homo sapiens_hsa051521.77545548
24TNF signaling pathway_Homo sapiens_hsa046681.76105361
25T cell receptor signaling pathway_Homo sapiens_hsa046601.75049955
26B cell receptor signaling pathway_Homo sapiens_hsa046621.70767210
27Jak-STAT signaling pathway_Homo sapiens_hsa046301.70011262
28Asthma_Homo sapiens_hsa053101.69144745
29Hematopoietic cell lineage_Homo sapiens_hsa046401.61074185
30Type I diabetes mellitus_Homo sapiens_hsa049401.57605014
31Autoimmune thyroid disease_Homo sapiens_hsa053201.54444266
32Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.51247983
33African trypanosomiasis_Homo sapiens_hsa051431.48786266
34Viral myocarditis_Homo sapiens_hsa054161.44158707
35Hepatitis C_Homo sapiens_hsa051601.42637135
36Rheumatoid arthritis_Homo sapiens_hsa053231.42467047
37Chemokine signaling pathway_Homo sapiens_hsa040621.41849188
38Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.40791027
39Salmonella infection_Homo sapiens_hsa051321.37369281
40Apoptosis_Homo sapiens_hsa042101.34357973
41Hepatitis B_Homo sapiens_hsa051611.30689085
42Caffeine metabolism_Homo sapiens_hsa002321.25024308
43Shigellosis_Homo sapiens_hsa051311.24370777
44Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.18922090
45Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.98495256
46Lysosome_Homo sapiens_hsa041420.98328483
47Leukocyte transendothelial migration_Homo sapiens_hsa046700.97373904
48Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.92980027
49Acute myeloid leukemia_Homo sapiens_hsa052210.91424266
50AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.88485794
51Prolactin signaling pathway_Homo sapiens_hsa049170.82995937
52Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.82568787
53Phagosome_Homo sapiens_hsa041450.81768744
54Dorso-ventral axis formation_Homo sapiens_hsa043200.76435226
55Regulation of autophagy_Homo sapiens_hsa041400.75617752
56Other glycan degradation_Homo sapiens_hsa005110.70423366
57Glycosaminoglycan degradation_Homo sapiens_hsa005310.69090725
58Complement and coagulation cascades_Homo sapiens_hsa046100.67968821
59Pancreatic cancer_Homo sapiens_hsa052120.66143079
60Amoebiasis_Homo sapiens_hsa051460.64223574
61Epstein-Barr virus infection_Homo sapiens_hsa051690.64109612
62Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.63881718
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62976285
64Glycerophospholipid metabolism_Homo sapiens_hsa005640.62902847
65alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.62332456
66Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.61296849
67Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.60871808
68Chronic myeloid leukemia_Homo sapiens_hsa052200.60415314
69Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.58837131
70Adipocytokine signaling pathway_Homo sapiens_hsa049200.55743874
71Viral carcinogenesis_Homo sapiens_hsa052030.53347177
72Platelet activation_Homo sapiens_hsa046110.52864393
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49295542
74Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48500066
75Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48060329
76Linoleic acid metabolism_Homo sapiens_hsa005910.47324312
77Small cell lung cancer_Homo sapiens_hsa052220.47096697
78HTLV-I infection_Homo sapiens_hsa051660.45570878
79HIF-1 signaling pathway_Homo sapiens_hsa040660.43792517
80Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43585540
81Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.43395062
82Phospholipase D signaling pathway_Homo sapiens_hsa040720.43389763
83Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.39990248
84Choline metabolism in cancer_Homo sapiens_hsa052310.39933259
85Ether lipid metabolism_Homo sapiens_hsa005650.39285119
86Prion diseases_Homo sapiens_hsa050200.38922572
87Inositol phosphate metabolism_Homo sapiens_hsa005620.38463212
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.37749959
89MAPK signaling pathway_Homo sapiens_hsa040100.37010693
90Arachidonic acid metabolism_Homo sapiens_hsa005900.36509215
91Collecting duct acid secretion_Homo sapiens_hsa049660.36495056
92VEGF signaling pathway_Homo sapiens_hsa043700.35846459
93Notch signaling pathway_Homo sapiens_hsa043300.34624561
94Transcriptional misregulation in cancer_Homo sapiens_hsa052020.34398011
95Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32171735
96Glycerolipid metabolism_Homo sapiens_hsa005610.32011096
97Proteasome_Homo sapiens_hsa030500.31975687
98Renal cell carcinoma_Homo sapiens_hsa052110.30510130
99ABC transporters_Homo sapiens_hsa020100.29341989
100Insulin resistance_Homo sapiens_hsa049310.27519902
101Morphine addiction_Homo sapiens_hsa050320.26636206
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.26519446
103Olfactory transduction_Homo sapiens_hsa047400.25463416
104mTOR signaling pathway_Homo sapiens_hsa041500.24708091
105Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.22941548
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.21522987
107p53 signaling pathway_Homo sapiens_hsa041150.20954518
108Regulation of actin cytoskeleton_Homo sapiens_hsa048100.20298476
109Endocytosis_Homo sapiens_hsa041440.20209586
110Arginine biosynthesis_Homo sapiens_hsa002200.16049298
111SNARE interactions in vesicular transport_Homo sapiens_hsa041300.15882267
112Mineral absorption_Homo sapiens_hsa049780.15074427
113Proteoglycans in cancer_Homo sapiens_hsa052050.14708863
114Pentose and glucuronate interconversions_Homo sapiens_hsa000400.14406838
115Type II diabetes mellitus_Homo sapiens_hsa049300.14196823
116Carbohydrate digestion and absorption_Homo sapiens_hsa049730.13870447
117Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.13165301
118FoxO signaling pathway_Homo sapiens_hsa040680.09911458
119Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.09525511
120Primary bile acid biosynthesis_Homo sapiens_hsa001200.06768496
121Colorectal cancer_Homo sapiens_hsa052100.06172381
122Pentose phosphate pathway_Homo sapiens_hsa000300.05746091
123Non-small cell lung cancer_Homo sapiens_hsa052230.04691210

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