

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 4.50525476 |
| 2 | regulation of histone H3-K27 methylation (GO:0061085) | 4.43176218 |
| 3 | cytoplasmic mRNA processing body assembly (GO:0033962) | 4.10243732 |
| 4 | peptidyl-lysine trimethylation (GO:0018023) | 4.08935113 |
| 5 | positive regulation of granulocyte differentiation (GO:0030854) | 3.91436680 |
| 6 | hepatocyte apoptotic process (GO:0097284) | 3.91416632 |
| 7 | regulation of RNA export from nucleus (GO:0046831) | 3.85178719 |
| 8 | cellular response to ethanol (GO:0071361) | 3.66509051 |
| 9 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.64877736 |
| 10 | establishment of protein localization to Golgi (GO:0072600) | 3.63105550 |
| 11 | nuclear pore complex assembly (GO:0051292) | 3.62789064 |
| 12 | histone demethylation (GO:0016577) | 3.60430249 |
| 13 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.57898747 |
| 14 | histone H3-K4 methylation (GO:0051568) | 3.51657572 |
| 15 | dosage compensation (GO:0007549) | 3.51132799 |
| 16 | regulation of DNA endoreduplication (GO:0032875) | 3.49099380 |
| 17 | histone lysine demethylation (GO:0070076) | 3.49014002 |
| 18 | negative regulation of dendrite morphogenesis (GO:0050774) | 3.43624954 |
| 19 | negative regulation of mast cell activation (GO:0033004) | 3.42958020 |
| 20 | protein targeting to Golgi (GO:0000042) | 3.39589341 |
| 21 | histone H3-K9 demethylation (GO:0033169) | 3.39250761 |
| 22 | interleukin-1-mediated signaling pathway (GO:0070498) | 3.32172751 |
| 23 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 3.32101361 |
| 24 | nuclear pore organization (GO:0006999) | 3.29741267 |
| 25 | protein dealkylation (GO:0008214) | 3.25293334 |
| 26 | protein demethylation (GO:0006482) | 3.25293334 |
| 27 | peptidyl-threonine dephosphorylation (GO:0035970) | 3.23629566 |
| 28 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.15559284 |
| 29 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.13660282 |
| 30 | peptidyl-lysine methylation (GO:0018022) | 3.13181929 |
| 31 | DNA synthesis involved in DNA repair (GO:0000731) | 3.11603042 |
| 32 | mitotic sister chromatid cohesion (GO:0007064) | 3.09025996 |
| 33 | ER overload response (GO:0006983) | 3.08985960 |
| 34 | definitive hemopoiesis (GO:0060216) | 3.08967310 |
| 35 | interferon-gamma production (GO:0032609) | 3.08063076 |
| 36 | Golgi to endosome transport (GO:0006895) | 3.04963614 |
| 37 | sister chromatid cohesion (GO:0007062) | 3.03413076 |
| 38 | pore complex assembly (GO:0046931) | 2.99828119 |
| 39 | COPII vesicle coating (GO:0048208) | 2.97141459 |
| 40 | protein K11-linked deubiquitination (GO:0035871) | 2.97095641 |
| 41 | corticosteroid receptor signaling pathway (GO:0031958) | 2.96475673 |
| 42 | N-terminal protein amino acid acetylation (GO:0006474) | 2.94187613 |
| 43 | regulation of centriole replication (GO:0046599) | 2.92736033 |
| 44 | regulation of germinal center formation (GO:0002634) | 2.92348994 |
| 45 | regulation of histone H3-K4 methylation (GO:0051569) | 2.91390384 |
| 46 | histone mRNA catabolic process (GO:0071044) | 2.90084033 |
| 47 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.89290848 |
| 48 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.89290848 |
| 49 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.89290848 |
| 50 | histone lysine methylation (GO:0034968) | 2.87139322 |
| 51 | embryonic process involved in female pregnancy (GO:0060136) | 2.85713738 |
| 52 | interkinetic nuclear migration (GO:0022027) | 2.85462205 |
| 53 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.84185128 |
| 54 | negative T cell selection (GO:0043383) | 2.83447676 |
| 55 | regulation of establishment of cell polarity (GO:2000114) | 2.83337370 |
| 56 | negative regulation of DNA repair (GO:0045738) | 2.80748754 |
| 57 | regulation of histone methylation (GO:0031060) | 2.79265472 |
| 58 | negative thymic T cell selection (GO:0045060) | 2.78532376 |
| 59 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.78210268 |
| 60 | response to UV-C (GO:0010225) | 2.75034718 |
| 61 | regulation of Rac protein signal transduction (GO:0035020) | 2.74847526 |
| 62 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.74094981 |
| 63 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.74094981 |
| 64 | histone H4-K16 acetylation (GO:0043984) | 2.73571763 |
| 65 | regulation of gamma-delta T cell activation (GO:0046643) | 2.72172569 |
| 66 | positive regulation of mRNA 3-end processing (GO:0031442) | 2.71704256 |
| 67 | regulation of protein polyubiquitination (GO:1902914) | 2.71275163 |
| 68 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787) | 2.69397456 |
| 69 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.69372559 |
| 70 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.67077576 |
| 71 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.67077576 |
| 72 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.65297409 |
| 73 | glutamate secretion (GO:0014047) | 2.65246852 |
| 74 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.65211516 |
| 75 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 2.62574227 |
| 76 | iron ion import (GO:0097286) | 2.61604141 |
| 77 | lipid translocation (GO:0034204) | 2.61377614 |
| 78 | phospholipid translocation (GO:0045332) | 2.61377614 |
| 79 | regulation of histone H3-K9 methylation (GO:0051570) | 2.61322053 |
| 80 | neural tube formation (GO:0001841) | 2.59998546 |
| 81 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.59835880 |
| 82 | startle response (GO:0001964) | 2.58626393 |
| 83 | snRNA transcription (GO:0009301) | 2.58354806 |
| 84 | dentate gyrus development (GO:0021542) | 2.57744705 |
| 85 | regulation of synaptic vesicle transport (GO:1902803) | 2.57643460 |
| 86 | B cell receptor signaling pathway (GO:0050853) | 2.57253409 |
| 87 | cellular response to interleukin-15 (GO:0071350) | 2.57136952 |
| 88 | protein K63-linked deubiquitination (GO:0070536) | 2.55351167 |
| 89 | response to peptidoglycan (GO:0032494) | 2.54421196 |
| 90 | ribonucleoprotein complex disassembly (GO:0032988) | 2.53723612 |
| 91 | regulation of mRNA catabolic process (GO:0061013) | 2.52868367 |
| 92 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.52783573 |
| 93 | synapsis (GO:0007129) | 2.52456762 |
| 94 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.50524202 |
| 95 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.50524202 |
| 96 | necrotic cell death (GO:0070265) | 2.50517610 |
| 97 | regulation of fibroblast apoptotic process (GO:2000269) | 2.50136264 |
| 98 | histone H3-K9 modification (GO:0061647) | 2.49562039 |
| 99 | peptidyl-threonine modification (GO:0018210) | 2.49336940 |
| 100 | DNA double-strand break processing (GO:0000729) | 2.49092145 |
| 101 | nucleus organization (GO:0006997) | 2.48949034 |
| 102 | cellular response to gamma radiation (GO:0071480) | 2.48108483 |
| 103 | peptidyl-threonine phosphorylation (GO:0018107) | 2.47510263 |
| 104 | superoxide anion generation (GO:0042554) | 2.47192045 |
| 105 | cellular extravasation (GO:0045123) | 2.46836873 |
| 106 | replication fork processing (GO:0031297) | 2.46199919 |
| 107 | chaperone mediated protein folding requiring cofactor (GO:0051085) | 2.45050863 |
| 108 | positive regulation of mRNA catabolic process (GO:0061014) | 2.44394541 |
| 109 | T cell selection (GO:0045058) | 2.44303616 |
| 110 | vocalization behavior (GO:0071625) | 2.42762441 |
| 111 | positive regulation of DNA-templated transcription, initiation (GO:2000144) | 2.41769394 |
| 112 | protein localization to Golgi apparatus (GO:0034067) | 2.41726826 |
| 113 | centriole replication (GO:0007099) | 2.41517197 |
| 114 | regulation of centrosome duplication (GO:0010824) | 2.40857497 |
| 115 | serotonin receptor signaling pathway (GO:0007210) | 2.40757667 |
| 116 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.40729869 |
| 117 | histone H3-K36 demethylation (GO:0070544) | 2.40341713 |
| 118 | regulation of meiosis I (GO:0060631) | 2.40200304 |
| 119 | synaptic transmission, glutamatergic (GO:0035249) | 2.39878669 |
| 120 | germinal center formation (GO:0002467) | 2.39163629 |
| 121 | long-term synaptic potentiation (GO:0060291) | 2.36058712 |
| 122 | myeloid leukocyte mediated immunity (GO:0002444) | 2.35803611 |
| 123 | necroptotic process (GO:0070266) | 2.35129945 |
| 124 | presynaptic membrane assembly (GO:0097105) | 2.34950474 |
| 125 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 2.34446076 |
| 126 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.34308682 |
| 127 | response to pheromone (GO:0019236) | 2.33041359 |
| 128 | programmed necrotic cell death (GO:0097300) | 2.31114906 |
| 129 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.25730923 |
| 130 | synaptic vesicle endocytosis (GO:0048488) | 2.24959166 |
| 131 | negative regulation of exocytosis (GO:0045920) | 2.24585851 |
| 132 | regulation of MHC class II biosynthetic process (GO:0045346) | 2.24476745 |
| 133 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.23484674 |
| 134 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.22356253 |
| 135 | neuron-neuron synaptic transmission (GO:0007270) | 2.21932202 |
| 136 | positive regulation of protein homodimerization activity (GO:0090073) | 2.20385647 |
| 137 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 2.18000415 |
| 138 | negative regulation of dendrite development (GO:2000171) | 2.15836991 |
| 139 | negative regulation of T cell mediated immunity (GO:0002710) | 2.15795366 |
| 140 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.15559612 |
| 141 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.14928609 |
| 142 | regulation of glucokinase activity (GO:0033131) | 2.14049933 |
| 143 | regulation of hexokinase activity (GO:1903299) | 2.14049933 |
| 144 | mitochondrion distribution (GO:0048311) | 2.13788331 |
| 145 | cellular response to antibiotic (GO:0071236) | 2.13561684 |
| 146 | microtubule depolymerization (GO:0007019) | 2.13116606 |
| 147 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.12942847 |
| 148 | neutrophil mediated immunity (GO:0002446) | 2.12026436 |
| 149 | positive regulation of cardiac muscle hypertrophy (GO:0010613) | 2.11738380 |
| 150 | positive regulation of muscle hypertrophy (GO:0014742) | 2.11738380 |
| 151 | negative regulation of meiosis (GO:0045835) | 2.11725597 |
| 152 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.10856226 |
| 153 | meiotic chromosome segregation (GO:0045132) | 2.10235704 |
| 154 | histone H3-K4 trimethylation (GO:0080182) | 2.08851782 |
| 155 | nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423) | 2.07641439 |
| 156 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.07577606 |
| 157 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.07294671 |
| 158 | glutamate receptor signaling pathway (GO:0007215) | 2.07071772 |
| 159 | protein K48-linked deubiquitination (GO:0071108) | 2.06226557 |
| 160 | positive regulation of osteoclast differentiation (GO:0045672) | 2.06112746 |
| 161 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.05357574 |
| 162 | neurotransmitter-gated ion channel clustering (GO:0072578) | 2.04830115 |
| 163 | regulation of respiratory gaseous exchange (GO:0043576) | 2.04307529 |
| 164 | protein K6-linked ubiquitination (GO:0085020) | 2.03608044 |
| 165 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.03510258 |
| 166 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.03401186 |
| 167 | response to interleukin-15 (GO:0070672) | 2.02060686 |
| 168 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.01929006 |
| 169 | RNA-dependent DNA replication (GO:0006278) | 2.01677976 |
| 170 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.01196259 |
| 171 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.01196259 |
| 172 | positive T cell selection (GO:0043368) | 2.00143148 |
| 173 | negative regulation of neurotransmitter secretion (GO:0046929) | 2.00044334 |
| 174 | inositol phosphate catabolic process (GO:0071545) | 1.99781607 |
| 175 | regulation of RIG-I signaling pathway (GO:0039535) | 1.99754699 |
| 176 | protein localization to microtubule cytoskeleton (GO:0072698) | 1.99430817 |
| 177 | cerebellar Purkinje cell differentiation (GO:0021702) | 1.97669689 |
| 178 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 1.97624534 |
| 179 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 1.97624534 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.29063662 |
| 2 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.63053221 |
| 3 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.22666416 |
| 4 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.01212000 |
| 5 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.88688831 |
| 6 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.68930046 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.62006485 |
| 8 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.56723587 |
| 9 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.56302087 |
| 10 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.52372226 |
| 11 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.29679401 |
| 12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.29537749 |
| 13 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 2.26587368 |
| 14 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.15951367 |
| 15 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.14002081 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 2.09866980 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 2.01927974 |
| 18 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.97888714 |
| 19 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.97780815 |
| 20 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.97228716 |
| 21 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.96658508 |
| 22 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.95320171 |
| 23 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.93661471 |
| 24 | MYB_26560356_Chip-Seq_TH2_Human | 1.90972205 |
| 25 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.90676846 |
| 26 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.90310101 |
| 27 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.87347132 |
| 28 | MYB_26560356_Chip-Seq_TH1_Human | 1.82959697 |
| 29 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.82682490 |
| 30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.81979148 |
| 31 | P300_19829295_ChIP-Seq_ESCs_Human | 1.80971830 |
| 32 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.79226207 |
| 33 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.78033378 |
| 34 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.78011430 |
| 35 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.70896666 |
| 36 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.69037511 |
| 37 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.67372041 |
| 38 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.66856482 |
| 39 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.65168494 |
| 40 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.65032871 |
| 41 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.64489754 |
| 42 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.62948263 |
| 43 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.61802287 |
| 44 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.58253756 |
| 45 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.56089067 |
| 46 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55499541 |
| 47 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.55332219 |
| 48 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.55317617 |
| 49 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.55137929 |
| 50 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.54396132 |
| 51 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.54196851 |
| 52 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.52072479 |
| 53 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.51857297 |
| 54 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.50044959 |
| 55 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.49998695 |
| 56 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.49701753 |
| 57 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.49590799 |
| 58 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.48473909 |
| 59 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.48167384 |
| 60 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.47906561 |
| 61 | STAT3_23295773_ChIP-Seq_U87_Human | 1.45496878 |
| 62 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.44687076 |
| 63 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.42159985 |
| 64 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.42089192 |
| 65 | VDR_22108803_ChIP-Seq_LS180_Human | 1.40755863 |
| 66 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.39073205 |
| 67 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.38083935 |
| 68 | TP53_16413492_ChIP-PET_HCT116_Human | 1.37698322 |
| 69 | * CIITA_25753668_ChIP-Seq_RAJI_Human | 1.37686990 |
| 70 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.37291620 |
| 71 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 1.37262471 |
| 72 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.34934203 |
| 73 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.34785507 |
| 74 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.33968311 |
| 75 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.32393422 |
| 76 | TCF4_23295773_ChIP-Seq_U87_Human | 1.31304768 |
| 77 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.30067179 |
| 78 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.29294602 |
| 79 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.29066598 |
| 80 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.27235220 |
| 81 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.27062064 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.26821225 |
| 83 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.26421437 |
| 84 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.25747356 |
| 85 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.24574138 |
| 86 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.24168157 |
| 87 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.23605804 |
| 88 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.23359986 |
| 89 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.23072180 |
| 90 | AR_25329375_ChIP-Seq_VCAP_Human | 1.22268063 |
| 91 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.21058107 |
| 92 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.20768679 |
| 93 | GATA3_26560356_Chip-Seq_TH2_Human | 1.20051963 |
| 94 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.18478529 |
| 95 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.18165353 |
| 96 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.16964232 |
| 97 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.16136346 |
| 98 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.15423552 |
| 99 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.15259765 |
| 100 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.15173562 |
| 101 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.14120178 |
| 102 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.13362954 |
| 103 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.12518273 |
| 104 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.12381359 |
| 105 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.11976094 |
| 106 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.11810724 |
| 107 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.11416302 |
| 108 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.11086198 |
| 109 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.09431349 |
| 110 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.08992053 |
| 111 | JUN_21703547_ChIP-Seq_K562_Human | 1.08663379 |
| 112 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.08322653 |
| 113 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.07637515 |
| 114 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.07075371 |
| 115 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.06992058 |
| 116 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.06779157 |
| 117 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.06779157 |
| 118 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.05556467 |
| 119 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.03952795 |
| 120 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.03569184 |
| 121 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.03369790 |
| 122 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03246012 |
| 123 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.02972040 |
| 124 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.02318455 |
| 125 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.01538939 |
| 126 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.01222603 |
| 127 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.00707956 |
| 128 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.00400068 |
| 129 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.00316042 |
| 130 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.99293377 |
| 131 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.98581493 |
| 132 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.98393852 |
| 133 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.97850957 |
| 134 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.97831826 |
| 135 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.97461197 |
| 136 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.97353361 |
| 137 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.95239002 |
| 138 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.95188219 |
| 139 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.94673748 |
| 140 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.94589314 |
| 141 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.94371405 |
| 142 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.93345833 |
| 143 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.93240065 |
| 144 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.92664417 |
| 145 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.92073746 |
| 146 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.91926945 |
| 147 | GATA1_22025678_ChIP-Seq_K562_Human | 0.91558783 |
| 148 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.90861410 |
| 149 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.90436329 |
| 150 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.88489619 |
| 151 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.88489619 |
| 152 | MYC_22102868_ChIP-Seq_BL_Human | 0.87524467 |
| 153 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.85388556 |
| 154 | GATA3_26560356_Chip-Seq_TH1_Human | 0.84959126 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008877_abnormal_DNA_methylation | 3.68680564 |
| 2 | MP0008057_abnormal_DNA_replication | 3.67367581 |
| 3 | MP0003787_abnormal_imprinting | 3.40686640 |
| 4 | MP0001188_hyperpigmentation | 3.04244127 |
| 5 | MP0005646_abnormal_pituitary_gland | 2.93304386 |
| 6 | MP0004859_abnormal_synaptic_plasticity | 2.62222695 |
| 7 | MP0000569_abnormal_digit_pigmentation | 2.55687049 |
| 8 | MP0005451_abnormal_body_composition | 2.55577033 |
| 9 | MP0002877_abnormal_melanocyte_morpholog | 2.51789498 |
| 10 | MP0003880_abnormal_central_pattern | 2.47284611 |
| 11 | MP0010352_gastrointestinal_tract_polyps | 2.35462819 |
| 12 | MP0001501_abnormal_sleep_pattern | 2.24303310 |
| 13 | MP0003221_abnormal_cardiomyocyte_apopto | 2.22054355 |
| 14 | MP0008007_abnormal_cellular_replicative | 2.06682164 |
| 15 | MP0001835_abnormal_antigen_presentation | 1.95636656 |
| 16 | MP0002822_catalepsy | 1.95329016 |
| 17 | MP0006292_abnormal_olfactory_placode | 1.94114565 |
| 18 | MP0002009_preneoplasia | 1.93274171 |
| 19 | MP0001177_atelectasis | 1.92884414 |
| 20 | MP0002735_abnormal_chemical_nociception | 1.84820604 |
| 21 | MP0003724_increased_susceptibility_to | 1.79612444 |
| 22 | MP0000015_abnormal_ear_pigmentation | 1.78867175 |
| 23 | MP0009745_abnormal_behavioral_response | 1.76200899 |
| 24 | MP0008961_abnormal_basal_metabolism | 1.75609362 |
| 25 | MP0002396_abnormal_hematopoietic_system | 1.74388838 |
| 26 | MP0003656_abnormal_erythrocyte_physiolo | 1.72390501 |
| 27 | MP0008058_abnormal_DNA_repair | 1.69201826 |
| 28 | MP0003635_abnormal_synaptic_transmissio | 1.66739743 |
| 29 | MP0010234_abnormal_vibrissa_follicle | 1.64876347 |
| 30 | MP0003111_abnormal_nucleus_morphology | 1.63513713 |
| 31 | MP0003693_abnormal_embryo_hatching | 1.62595771 |
| 32 | MP0004381_abnormal_hair_follicle | 1.60324033 |
| 33 | MP0004808_abnormal_hematopoietic_stem | 1.60242115 |
| 34 | MP0001986_abnormal_taste_sensitivity | 1.55612247 |
| 35 | MP0010678_abnormal_skin_adnexa | 1.54431858 |
| 36 | MP0010094_abnormal_chromosome_stability | 1.52463660 |
| 37 | MP0004264_abnormal_extraembryonic_tissu | 1.52018905 |
| 38 | MP0000427_abnormal_hair_cycle | 1.50325985 |
| 39 | MP0005671_abnormal_response_to | 1.49659675 |
| 40 | MP0002063_abnormal_learning/memory/cond | 1.48984433 |
| 41 | MP0003121_genomic_imprinting | 1.48419185 |
| 42 | MP0005171_absent_coat_pigmentation | 1.47865519 |
| 43 | MP0010307_abnormal_tumor_latency | 1.47232399 |
| 44 | MP0003950_abnormal_plasma_membrane | 1.41575230 |
| 45 | MP0002572_abnormal_emotion/affect_behav | 1.41356760 |
| 46 | MP0005645_abnormal_hypothalamus_physiol | 1.39287112 |
| 47 | MP0002006_tumorigenesis | 1.38977031 |
| 48 | MP0004185_abnormal_adipocyte_glucose | 1.38290128 |
| 49 | MP0002876_abnormal_thyroid_physiology | 1.38143154 |
| 50 | MP0005423_abnormal_somatic_nervous | 1.35928691 |
| 51 | MP0000383_abnormal_hair_follicle | 1.35697404 |
| 52 | MP0009046_muscle_twitch | 1.35379354 |
| 53 | MP0002722_abnormal_immune_system | 1.34292485 |
| 54 | MP0000350_abnormal_cell_proliferation | 1.31561089 |
| 55 | MP0005000_abnormal_immune_tolerance | 1.30114022 |
| 56 | MP0003123_paternal_imprinting | 1.28744830 |
| 57 | MP0002064_seizures | 1.27620309 |
| 58 | MP0001968_abnormal_touch/_nociception | 1.25617063 |
| 59 | MP0003763_abnormal_thymus_physiology | 1.25284633 |
| 60 | MP0005367_renal/urinary_system_phenotyp | 1.23415342 |
| 61 | MP0000516_abnormal_urinary_system | 1.23415342 |
| 62 | MP0003828_pulmonary_edema | 1.23350752 |
| 63 | MP0005076_abnormal_cell_differentiation | 1.22084622 |
| 64 | MP0005310_abnormal_salivary_gland | 1.18438739 |
| 65 | MP0001851_eye_inflammation | 1.17200271 |
| 66 | MP0002419_abnormal_innate_immunity | 1.16931523 |
| 67 | MP0003300_gastrointestinal_ulcer | 1.16866622 |
| 68 | MP0003786_premature_aging | 1.16627845 |
| 69 | MP0002148_abnormal_hypersensitivity_rea | 1.16381348 |
| 70 | MP0001800_abnormal_humoral_immune | 1.15694284 |
| 71 | MP0002452_abnormal_antigen_presenting | 1.14256165 |
| 72 | MP0002272_abnormal_nervous_system | 1.14153577 |
| 73 | MP0002736_abnormal_nociception_after | 1.14011025 |
| 74 | MP0001191_abnormal_skin_condition | 1.13606227 |
| 75 | MP0002132_abnormal_respiratory_system | 1.12634865 |
| 76 | MP0009785_altered_susceptibility_to | 1.12464190 |
| 77 | MP0003941_abnormal_skin_development | 1.11863813 |
| 78 | MP0004957_abnormal_blastocyst_morpholog | 1.11749578 |
| 79 | MP0004924_abnormal_behavior | 1.11661626 |
| 80 | MP0005386_behavior/neurological_phenoty | 1.11661626 |
| 81 | MP0002420_abnormal_adaptive_immunity | 1.11659002 |
| 82 | MP0002723_abnormal_immune_serum | 1.11530052 |
| 83 | MP0001819_abnormal_immune_cell | 1.09493438 |
| 84 | MP0002019_abnormal_tumor_incidence | 1.09336390 |
| 85 | MP0004484_altered_response_of | 1.08915519 |
| 86 | MP0009115_abnormal_fat_cell | 1.08262721 |
| 87 | MP0001790_abnormal_immune_system | 1.06640742 |
| 88 | MP0005387_immune_system_phenotype | 1.06640742 |
| 89 | MP0002088_abnormal_embryonic_growth/wei | 1.04786628 |
| 90 | MP0005621_abnormal_cell_physiology | 1.02689714 |
| 91 | MP0003984_embryonic_growth_retardation | 1.02633616 |
| 92 | MP0002277_abnormal_respiratory_mucosa | 1.02099050 |
| 93 | MP0003077_abnormal_cell_cycle | 1.01846627 |
| 94 | MP0002429_abnormal_blood_cell | 1.00569108 |
| 95 | MP0009697_abnormal_copulation | 1.00481832 |
| 96 | MP0002398_abnormal_bone_marrow | 0.99165879 |
| 97 | MP0008260_abnormal_autophagy | 0.98588836 |
| 98 | MP0002086_abnormal_extraembryonic_tissu | 0.96599007 |
| 99 | MP0005380_embryogenesis_phenotype | 0.96299007 |
| 100 | MP0001672_abnormal_embryogenesis/_devel | 0.96299007 |
| 101 | MP0002734_abnormal_mechanical_nocicepti | 0.96265106 |
| 102 | MP0003890_abnormal_embryonic-extraembry | 0.95810907 |
| 103 | MP0003091_abnormal_cell_migration | 0.95467595 |
| 104 | MP0005075_abnormal_melanosome_morpholog | 0.93090894 |
| 105 | MP0005174_abnormal_tail_pigmentation | 0.92544410 |
| 106 | MP0001486_abnormal_startle_reflex | 0.89418463 |
| 107 | MP0002166_altered_tumor_susceptibility | 0.89281405 |
| 108 | MP0004782_abnormal_surfactant_physiolog | 0.88958247 |
| 109 | MP0001929_abnormal_gametogenesis | 0.88911181 |
| 110 | MP0003252_abnormal_bile_duct | 0.88649379 |
| 111 | MP0003943_abnormal_hepatobiliary_system | 0.88620566 |
| 112 | MP0003183_abnormal_peptide_metabolism | 0.87734798 |
| 113 | MP0001984_abnormal_olfaction | 0.86309074 |
| 114 | MP0000377_abnormal_hair_follicle | 0.85718159 |
| 115 | MP0005397_hematopoietic_system_phenotyp | 0.85023789 |
| 116 | MP0001545_abnormal_hematopoietic_system | 0.85023789 |
| 117 | MP0003868_abnormal_feces_composition | 0.84977333 |
| 118 | MP0005409_darkened_coat_color | 0.84836289 |
| 119 | MP0002095_abnormal_skin_pigmentation | 0.84502489 |
| 120 | MP0002163_abnormal_gland_morphology | 0.84221272 |
| 121 | MP0003453_abnormal_keratinocyte_physiol | 0.83986999 |
| 122 | MP0002067_abnormal_sensory_capabilities | 0.83598454 |
| 123 | MP0002332_abnormal_exercise_endurance | 0.83186549 |
| 124 | MP0004147_increased_porphyrin_level | 0.82678759 |
| 125 | MP0001697_abnormal_embryo_size | 0.82653441 |
| 126 | MP0010155_abnormal_intestine_physiology | 0.82512812 |
| 127 | MP0004947_skin_inflammation | 0.81557993 |
| 128 | MP0004134_abnormal_chest_morphology | 0.80276018 |
| 129 | MP0000313_abnormal_cell_death | 0.79840705 |
| 130 | MP0004233_abnormal_muscle_weight | 0.79788968 |
| 131 | MP0003448_altered_tumor_morphology | 0.78774063 |
| 132 | MP0005384_cellular_phenotype | 0.78628131 |
| 133 | MP0010386_abnormal_urinary_bladder | 0.78278244 |
| 134 | MP0000703_abnormal_thymus_morphology | 0.78151970 |
| 135 | MP0001216_abnormal_epidermal_layer | 0.78104061 |
| 136 | MP0000716_abnormal_immune_system | 0.77958581 |
| 137 | MP0001119_abnormal_female_reproductive | 0.77857413 |
| 138 | MP0005666_abnormal_adipose_tissue | 0.77381040 |
| 139 | MP0008995_early_reproductive_senescence | 0.76538020 |
| 140 | MP0002796_impaired_skin_barrier | 0.76521904 |
| 141 | MP0005647_abnormal_sex_gland | 0.76187381 |
| 142 | MP0003045_fibrosis | 0.76162754 |
| 143 | MP0003436_decreased_susceptibility_to | 0.76065118 |
| 144 | MP0002638_abnormal_pupillary_reflex | 0.75397047 |
| 145 | MP0005266_abnormal_metabolism | 0.75393926 |
| 146 | MP0000685_abnormal_immune_system | 0.75135977 |
| 147 | MP0001730_embryonic_growth_arrest | 0.74787418 |
| 148 | MP0002928_abnormal_bile_duct | 0.73639059 |
| 149 | MP0006276_abnormal_autonomic_nervous | 0.73362376 |
| 150 | MP0009765_abnormal_xenobiotic_induced | 0.72488336 |
| 151 | MP0000371_diluted_coat_color | 0.72369084 |
| 152 | MP0002133_abnormal_respiratory_system | 0.72232811 |
| 153 | MP0005388_respiratory_system_phenotype | 0.72232811 |
| 154 | MP0004197_abnormal_fetal_growth/weight/ | 0.72231639 |
| 155 | MP0001502_abnormal_circadian_rhythm | 0.72186934 |
| 156 | MP0002557_abnormal_social/conspecific_i | 0.71783837 |
| 157 | MP0002998_abnormal_bone_remodeling | 0.71760473 |
| 158 | MP0002160_abnormal_reproductive_system | 0.71267467 |
| 159 | MP0001186_pigmentation_phenotype | 0.70671111 |
| 160 | MP0000689_abnormal_spleen_morphology | 0.69887407 |
| 161 | MP0001919_abnormal_reproductive_system | 0.69352253 |
| 162 | MP0001542_abnormal_bone_strength | 0.68376642 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Febrile seizures (HP:0002373) | 4.36180124 |
| 2 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.20645224 |
| 3 | Chromsome breakage (HP:0040012) | 4.17169979 |
| 4 | Focal motor seizures (HP:0011153) | 3.70671070 |
| 5 | Abnormal hair whorl (HP:0010721) | 3.65393642 |
| 6 | Prostate neoplasm (HP:0100787) | 3.60945411 |
| 7 | Acute lymphatic leukemia (HP:0006721) | 3.25629802 |
| 8 | Optic neuritis (HP:0100653) | 3.16211663 |
| 9 | Retrobulbar optic neuritis (HP:0100654) | 3.16211663 |
| 10 | Birth length less than 3rd percentile (HP:0003561) | 3.05004912 |
| 11 | Generalized hypopigmentation of hair (HP:0011358) | 3.04708200 |
| 12 | Submucous cleft hard palate (HP:0000176) | 2.95989773 |
| 13 | Fair hair (HP:0002286) | 2.94625583 |
| 14 | Subacute progressive viral hepatitis (HP:0006572) | 2.93574350 |
| 15 | Autoimmune hemolytic anemia (HP:0001890) | 2.91374402 |
| 16 | Atonic seizures (HP:0010819) | 2.88726082 |
| 17 | Epileptic encephalopathy (HP:0200134) | 2.86314230 |
| 18 | Papillary thyroid carcinoma (HP:0002895) | 2.85694779 |
| 19 | Heterotopia (HP:0002282) | 2.76775444 |
| 20 | Alveolar cell carcinoma (HP:0006519) | 2.70905344 |
| 21 | Dysmetric saccades (HP:0000641) | 2.68042188 |
| 22 | Prominent nose (HP:0000448) | 2.65957061 |
| 23 | Protruding tongue (HP:0010808) | 2.65502321 |
| 24 | Curly hair (HP:0002212) | 2.64969872 |
| 25 | Recurrent bacterial skin infections (HP:0005406) | 2.59699156 |
| 26 | Truncal obesity (HP:0001956) | 2.57513842 |
| 27 | Sandal gap (HP:0001852) | 2.54541466 |
| 28 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.53784113 |
| 29 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.52896237 |
| 30 | Abnormality of T cell number (HP:0011839) | 2.42990071 |
| 31 | Acute myeloid leukemia (HP:0004808) | 2.42032397 |
| 32 | T lymphocytopenia (HP:0005403) | 2.39718439 |
| 33 | Neoplasm of the adrenal cortex (HP:0100641) | 2.39480465 |
| 34 | Spinal cord lesions (HP:0100561) | 2.39473032 |
| 35 | Syringomyelia (HP:0003396) | 2.39473032 |
| 36 | Ankyloglossia (HP:0010296) | 2.39359698 |
| 37 | Abnormality of oral frenula (HP:0000190) | 2.36042826 |
| 38 | Lower limb hyperreflexia (HP:0002395) | 2.32801187 |
| 39 | Short chin (HP:0000331) | 2.31189410 |
| 40 | Abnormality of the prostate (HP:0008775) | 2.31066508 |
| 41 | Central scotoma (HP:0000603) | 2.29263955 |
| 42 | Sparse lateral eyebrow (HP:0005338) | 2.27119170 |
| 43 | Low anterior hairline (HP:0000294) | 2.26866122 |
| 44 | Thyroid carcinoma (HP:0002890) | 2.22277460 |
| 45 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.21930774 |
| 46 | Hypoplasia of the fovea (HP:0007750) | 2.21930774 |
| 47 | Abnormality of the fingertips (HP:0001211) | 2.21757272 |
| 48 | Capillary hemangiomas (HP:0005306) | 2.20558249 |
| 49 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.18207018 |
| 50 | Lip pit (HP:0100267) | 2.16567751 |
| 51 | Abnormality of chromosome stability (HP:0003220) | 2.16119181 |
| 52 | Focal seizures (HP:0007359) | 2.15181549 |
| 53 | Relative macrocephaly (HP:0004482) | 2.13567915 |
| 54 | Abnormality of chromosome segregation (HP:0002916) | 2.13310297 |
| 55 | Horizontal nystagmus (HP:0000666) | 2.12899460 |
| 56 | Gaze-evoked nystagmus (HP:0000640) | 2.12854225 |
| 57 | Myelodysplasia (HP:0002863) | 2.11981296 |
| 58 | Volvulus (HP:0002580) | 2.10040750 |
| 59 | Keratoconjunctivitis sicca (HP:0001097) | 2.09756348 |
| 60 | Orchitis (HP:0100796) | 2.08618737 |
| 61 | Pelvic girdle muscle weakness (HP:0003749) | 2.07578696 |
| 62 | Abnormality of the nasal septum (HP:0000419) | 2.07144333 |
| 63 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.06578598 |
| 64 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.06578598 |
| 65 | Tapered finger (HP:0001182) | 2.05199538 |
| 66 | Progressive external ophthalmoplegia (HP:0000590) | 2.02576621 |
| 67 | Ectopic kidney (HP:0000086) | 2.00463079 |
| 68 | Fatigue (HP:0012378) | 1.96860872 |
| 69 | Viral hepatitis (HP:0006562) | 1.96713755 |
| 70 | Shoulder girdle muscle weakness (HP:0003547) | 1.96523082 |
| 71 | Abnormality of the preputium (HP:0100587) | 1.95357775 |
| 72 | Meckel diverticulum (HP:0002245) | 1.94804971 |
| 73 | Cafe-au-lait spot (HP:0000957) | 1.94361592 |
| 74 | Blue irides (HP:0000635) | 1.94042389 |
| 75 | Hyperventilation (HP:0002883) | 1.94042370 |
| 76 | Clubbing of toes (HP:0100760) | 1.92003343 |
| 77 | Menstrual irregularities (HP:0000858) | 1.91316288 |
| 78 | Basal cell carcinoma (HP:0002671) | 1.90988940 |
| 79 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.90890709 |
| 80 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.90890709 |
| 81 | Mediastinal lymphadenopathy (HP:0100721) | 1.90583673 |
| 82 | Acute hepatic failure (HP:0006554) | 1.88787790 |
| 83 | Slow saccadic eye movements (HP:0000514) | 1.87888030 |
| 84 | Stomatitis (HP:0010280) | 1.87411394 |
| 85 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 1.86925768 |
| 86 | Abnormal spermatogenesis (HP:0008669) | 1.86918288 |
| 87 | Poor eye contact (HP:0000817) | 1.86498403 |
| 88 | Keratoconjunctivitis (HP:0001096) | 1.86095301 |
| 89 | Abnormality of the renal collecting system (HP:0004742) | 1.85820596 |
| 90 | Intestinal atresia (HP:0011100) | 1.85518836 |
| 91 | Thyroiditis (HP:0100646) | 1.85345020 |
| 92 | Hypoplastic iliac wings (HP:0002866) | 1.85042582 |
| 93 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.84959231 |
| 94 | Tubulointerstitial nephritis (HP:0001970) | 1.84753662 |
| 95 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.84566032 |
| 96 | Urethral obstruction (HP:0000796) | 1.82694167 |
| 97 | Deep philtrum (HP:0002002) | 1.82057359 |
| 98 | Abnormality of B cell number (HP:0010975) | 1.81908332 |
| 99 | Broad-based gait (HP:0002136) | 1.81754344 |
| 100 | Medial flaring of the eyebrow (HP:0010747) | 1.80988446 |
| 101 | Recurrent abscess formation (HP:0002722) | 1.80771674 |
| 102 | Abnormality of incisor morphology (HP:0011063) | 1.80661623 |
| 103 | Abnormality of the labia minora (HP:0012880) | 1.79230622 |
| 104 | Agnosia (HP:0010524) | 1.79136006 |
| 105 | Absent frontal sinuses (HP:0002688) | 1.78966991 |
| 106 | Widely spaced teeth (HP:0000687) | 1.78860297 |
| 107 | IgG deficiency (HP:0004315) | 1.78824189 |
| 108 | Rhabdomyosarcoma (HP:0002859) | 1.78651471 |
| 109 | Abnormality of the ileum (HP:0001549) | 1.78626044 |
| 110 | Azoospermia (HP:0000027) | 1.78067305 |
| 111 | Chronic hepatic failure (HP:0100626) | 1.77868925 |
| 112 | Macroorchidism (HP:0000053) | 1.77809263 |
| 113 | Agammaglobulinemia (HP:0004432) | 1.77654145 |
| 114 | Abnormality of the fovea (HP:0000493) | 1.77465348 |
| 115 | Thickened calvaria (HP:0002684) | 1.76963683 |
| 116 | Gonadotropin excess (HP:0000837) | 1.76544650 |
| 117 | Recurrent viral infections (HP:0004429) | 1.76100250 |
| 118 | Inability to walk (HP:0002540) | 1.75214324 |
| 119 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.74977118 |
| 120 | Eczematoid dermatitis (HP:0000976) | 1.74305435 |
| 121 | Poor coordination (HP:0002370) | 1.73146691 |
| 122 | Narrow palate (HP:0000189) | 1.73063826 |
| 123 | Stomach cancer (HP:0012126) | 1.73038697 |
| 124 | Somatic mutation (HP:0001428) | 1.72360494 |
| 125 | Chronic diarrhea (HP:0002028) | 1.71545604 |
| 126 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.70871084 |
| 127 | Subaortic stenosis (HP:0001682) | 1.70871084 |
| 128 | Myositis (HP:0100614) | 1.70449791 |
| 129 | Genetic anticipation (HP:0003743) | 1.70441338 |
| 130 | Gastrointestinal infarctions (HP:0005244) | 1.70324093 |
| 131 | Limb hypertonia (HP:0002509) | 1.69796550 |
| 132 | Septate vagina (HP:0001153) | 1.69714931 |
| 133 | Pustule (HP:0200039) | 1.69650740 |
| 134 | Keratitis (HP:0000491) | 1.69345956 |
| 135 | Abnormality of T cells (HP:0002843) | 1.68063083 |
| 136 | Bone marrow hypocellularity (HP:0005528) | 1.67740413 |
| 137 | Pulmonary infiltrates (HP:0002113) | 1.66473102 |
| 138 | Embryonal renal neoplasm (HP:0011794) | 1.65744496 |
| 139 | Coarse hair (HP:0002208) | 1.65695885 |
| 140 | Glioma (HP:0009733) | 1.65402243 |
| 141 | Glomerulopathy (HP:0100820) | 1.65252103 |
| 142 | Cystic hygroma (HP:0000476) | 1.65005625 |
| 143 | Encephalitis (HP:0002383) | 1.64988163 |
| 144 | Recurrent pneumonia (HP:0006532) | 1.64924689 |
| 145 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.64803012 |
| 146 | Recurrent cutaneous fungal infections (HP:0011370) | 1.64803012 |
| 147 | Excessive salivation (HP:0003781) | 1.64435097 |
| 148 | Drooling (HP:0002307) | 1.64435097 |
| 149 | Increased number of teeth (HP:0011069) | 1.64306830 |
| 150 | Meningitis (HP:0001287) | 1.64231829 |
| 151 | Entropion (HP:0000621) | 1.63816208 |
| 152 | Cutis marmorata (HP:0000965) | 1.63790751 |
| 153 | Duplicated collecting system (HP:0000081) | 1.63778197 |
| 154 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 1.63686282 |
| 155 | Absent speech (HP:0001344) | 1.61578310 |
| 156 | Oligodactyly (hands) (HP:0001180) | 1.61547151 |
| 157 | Chest pain (HP:0100749) | 1.61165153 |
| 158 | Conjugated hyperbilirubinemia (HP:0002908) | 1.60711613 |
| 159 | Nephrogenic diabetes insipidus (HP:0009806) | 1.60476616 |
| 160 | Generalized tonic-clonic seizures (HP:0002069) | 1.60327328 |
| 161 | Freckling (HP:0001480) | 1.59547444 |
| 162 | Breast carcinoma (HP:0003002) | 1.59399061 |
| 163 | Absence seizures (HP:0002121) | 1.59269751 |
| 164 | Abnormality of T cell physiology (HP:0011840) | 1.59048140 |
| 165 | Abnormal foot bone ossification (HP:0010675) | 1.58862990 |
| 166 | Obsessive-compulsive behavior (HP:0000722) | 1.57913037 |
| 167 | Urinary urgency (HP:0000012) | 1.55210780 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | AKT3 | 3.36377695 |
| 2 | MAP3K14 | 3.02314617 |
| 3 | IRAK3 | 3.01428130 |
| 4 | TXK | 2.85416903 |
| 5 | ZAK | 2.70213098 |
| 6 | SGK2 | 2.39712290 |
| 7 | PLK2 | 2.38139825 |
| 8 | CASK | 2.30756553 |
| 9 | BMPR1B | 2.18733833 |
| 10 | MAP3K12 | 2.08646157 |
| 11 | PLK4 | 2.08172131 |
| 12 | TSSK6 | 1.97715060 |
| 13 | MAP2K7 | 1.96664725 |
| 14 | BMPR2 | 1.95191530 |
| 15 | RIPK4 | 1.94915927 |
| 16 | SCYL2 | 1.91528006 |
| 17 | NTRK3 | 1.88724419 |
| 18 | PRPF4B | 1.88292087 |
| 19 | FRK | 1.88149872 |
| 20 | INSRR | 1.69111188 |
| 21 | IRAK4 | 1.66366789 |
| 22 | ACVR1B | 1.63641868 |
| 23 | IRAK2 | 1.62815619 |
| 24 | SGK3 | 1.62705672 |
| 25 | MAP3K2 | 1.60520840 |
| 26 | MKNK2 | 1.53567322 |
| 27 | EPHA4 | 1.48266499 |
| 28 | KSR1 | 1.47186693 |
| 29 | NEK6 | 1.45974183 |
| 30 | CAMK1D | 1.44558567 |
| 31 | BLK | 1.40514767 |
| 32 | PLK3 | 1.38752618 |
| 33 | IKBKE | 1.36201104 |
| 34 | PIK3CG | 1.33006203 |
| 35 | MST4 | 1.32125359 |
| 36 | SGK223 | 1.32070595 |
| 37 | SGK494 | 1.32070595 |
| 38 | CAMK1G | 1.31416183 |
| 39 | RAF1 | 1.29274094 |
| 40 | SIK3 | 1.24592827 |
| 41 | MAP3K10 | 1.23221738 |
| 42 | TEC | 1.22285227 |
| 43 | BRSK2 | 1.21093389 |
| 44 | ERBB3 | 1.19672995 |
| 45 | EPHA3 | 1.18632555 |
| 46 | NUAK1 | 1.17390857 |
| 47 | BRD4 | 1.16317630 |
| 48 | WEE1 | 1.15657141 |
| 49 | STK3 | 1.12363618 |
| 50 | TYK2 | 1.09303935 |
| 51 | CCNB1 | 1.08718287 |
| 52 | CLK1 | 1.08042673 |
| 53 | MAPK7 | 1.07697397 |
| 54 | RPS6KB2 | 1.07226739 |
| 55 | MAP3K4 | 1.04847406 |
| 56 | BTK | 1.04254561 |
| 57 | CDK6 | 1.03769939 |
| 58 | RPS6KA4 | 1.01173014 |
| 59 | YES1 | 0.99877577 |
| 60 | PASK | 0.98705520 |
| 61 | IKBKB | 0.97037126 |
| 62 | KSR2 | 0.95418247 |
| 63 | CDK3 | 0.94957560 |
| 64 | CAMKK2 | 0.93384150 |
| 65 | TRPM7 | 0.93367600 |
| 66 | EIF2AK3 | 0.93133281 |
| 67 | SRPK1 | 0.91556366 |
| 68 | EIF2AK1 | 0.91551293 |
| 69 | MUSK | 0.88941709 |
| 70 | HCK | 0.86528309 |
| 71 | PINK1 | 0.86251022 |
| 72 | JAK2 | 0.82064972 |
| 73 | EIF2AK2 | 0.81467546 |
| 74 | CDK8 | 0.79900546 |
| 75 | MELK | 0.78719480 |
| 76 | MAP3K13 | 0.77599142 |
| 77 | PNCK | 0.76588976 |
| 78 | MKNK1 | 0.76491169 |
| 79 | EEF2K | 0.76241130 |
| 80 | VRK1 | 0.76001224 |
| 81 | PDK2 | 0.75766607 |
| 82 | CDC7 | 0.74451563 |
| 83 | MAP3K5 | 0.74433675 |
| 84 | DAPK1 | 0.71809327 |
| 85 | TRIM28 | 0.71723514 |
| 86 | JAK1 | 0.71524462 |
| 87 | WNK1 | 0.71307769 |
| 88 | STK10 | 0.70627813 |
| 89 | PDK1 | 0.70088227 |
| 90 | PIM1 | 0.68931243 |
| 91 | MARK3 | 0.66904896 |
| 92 | STK38L | 0.66287729 |
| 93 | STK24 | 0.66125130 |
| 94 | CHUK | 0.66120207 |
| 95 | SGK1 | 0.65743262 |
| 96 | RPS6KB1 | 0.65420138 |
| 97 | MAP2K3 | 0.65138152 |
| 98 | BRAF | 0.64651417 |
| 99 | TAOK3 | 0.64038932 |
| 100 | MAP3K9 | 0.63055545 |
| 101 | JAK3 | 0.62348522 |
| 102 | TNK2 | 0.59598040 |
| 103 | FGFR3 | 0.58496408 |
| 104 | ATM | 0.57782371 |
| 105 | FER | 0.56313737 |
| 106 | PRKCH | 0.56004318 |
| 107 | BRSK1 | 0.54633336 |
| 108 | DYRK1A | 0.53048315 |
| 109 | NLK | 0.51495593 |
| 110 | IRAK1 | 0.51043209 |
| 111 | MAP4K1 | 0.49725332 |
| 112 | CSF1R | 0.49210530 |
| 113 | TGFBR1 | 0.48581485 |
| 114 | PRKCE | 0.48113913 |
| 115 | MAPK13 | 0.46735366 |
| 116 | ATR | 0.46512232 |
| 117 | CDK12 | 0.46469280 |
| 118 | ADRBK2 | 0.45408442 |
| 119 | CAMKK1 | 0.45407826 |
| 120 | SYK | 0.43785523 |
| 121 | RET | 0.43453833 |
| 122 | MTOR | 0.43292241 |
| 123 | CSK | 0.43239463 |
| 124 | MAP3K1 | 0.42947575 |
| 125 | CDK4 | 0.42809605 |
| 126 | STK16 | 0.42082340 |
| 127 | LATS1 | 0.41417060 |
| 128 | MAP2K4 | 0.41141054 |
| 129 | ITK | 0.40901167 |
| 130 | GRK6 | 0.40246568 |
| 131 | MAP3K7 | 0.39410968 |
| 132 | EGFR | 0.38822198 |
| 133 | DAPK2 | 0.36854386 |
| 134 | MAP3K6 | 0.36651426 |
| 135 | PRKCG | 0.35816029 |
| 136 | * CHEK1 | 0.35205418 |
| 137 | GRK7 | 0.34994132 |
| 138 | ALK | 0.34113137 |
| 139 | RPS6KA2 | 0.33889344 |
| 140 | MINK1 | 0.32632337 |
| 141 | LYN | 0.31543520 |
| 142 | WNK3 | 0.29808856 |
| 143 | MAPK14 | 0.28695143 |
| 144 | CHEK2 | 0.27605796 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 2.42696408 |
| 2 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.11886100 |
| 3 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 2.04428199 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.95908790 |
| 5 | Long-term potentiation_Homo sapiens_hsa04720 | 1.73119909 |
| 6 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.71528614 |
| 7 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.69026425 |
| 8 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.61378339 |
| 9 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.60656840 |
| 10 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.60436257 |
| 11 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.53717957 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.52849615 |
| 13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.51306299 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.47639445 |
| 15 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.46239742 |
| 16 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.45404413 |
| 17 | Olfactory transduction_Homo sapiens_hsa04740 | 1.44470092 |
| 18 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.43656780 |
| 19 | Allograft rejection_Homo sapiens_hsa05330 | 1.43019047 |
| 20 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.42556309 |
| 21 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.40808964 |
| 22 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.40806522 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.37015694 |
| 24 | Measles_Homo sapiens_hsa05162 | 1.35919000 |
| 25 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.35680386 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.35103373 |
| 27 | Homologous recombination_Homo sapiens_hsa03440 | 1.34024240 |
| 28 | Morphine addiction_Homo sapiens_hsa05032 | 1.31664901 |
| 29 | Circadian entrainment_Homo sapiens_hsa04713 | 1.31272511 |
| 30 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.29249086 |
| 31 | Taste transduction_Homo sapiens_hsa04742 | 1.28769297 |
| 32 | Colorectal cancer_Homo sapiens_hsa05210 | 1.27578297 |
| 33 | Endometrial cancer_Homo sapiens_hsa05213 | 1.26810770 |
| 34 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.25555711 |
| 35 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.24207518 |
| 36 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.23975422 |
| 37 | Leishmaniasis_Homo sapiens_hsa05140 | 1.23808075 |
| 38 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.17213916 |
| 39 | GABAergic synapse_Homo sapiens_hsa04727 | 1.16133032 |
| 40 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.14425969 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 1.12978307 |
| 42 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.11478306 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 1.11422768 |
| 44 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.11237233 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.10051931 |
| 46 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.10008053 |
| 47 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.09589111 |
| 48 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.09243868 |
| 49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.08771246 |
| 50 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.08484494 |
| 51 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.06921634 |
| 52 | Insulin secretion_Homo sapiens_hsa04911 | 1.06747849 |
| 53 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.05837737 |
| 54 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.04332828 |
| 55 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.04261461 |
| 56 | Influenza A_Homo sapiens_hsa05164 | 1.03912844 |
| 57 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.02484670 |
| 58 | Protein export_Homo sapiens_hsa03060 | 1.02270271 |
| 59 | Cell cycle_Homo sapiens_hsa04110 | 1.02182943 |
| 60 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.99875564 |
| 61 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.99557269 |
| 62 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.99546450 |
| 63 | Platelet activation_Homo sapiens_hsa04611 | 0.99065829 |
| 64 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.98023889 |
| 65 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.97772637 |
| 66 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.97616398 |
| 67 | Circadian rhythm_Homo sapiens_hsa04710 | 0.97051017 |
| 68 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.96947456 |
| 69 | Cocaine addiction_Homo sapiens_hsa05030 | 0.96945814 |
| 70 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.96282993 |
| 71 | Legionellosis_Homo sapiens_hsa05134 | 0.96192144 |
| 72 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.95957877 |
| 73 | Long-term depression_Homo sapiens_hsa04730 | 0.95561116 |
| 74 | Thyroid cancer_Homo sapiens_hsa05216 | 0.94583201 |
| 75 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.93345843 |
| 76 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.93288769 |
| 77 | Hepatitis C_Homo sapiens_hsa05160 | 0.93155234 |
| 78 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.93051568 |
| 79 | RNA degradation_Homo sapiens_hsa03018 | 0.92661739 |
| 80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.91469108 |
| 81 | Apoptosis_Homo sapiens_hsa04210 | 0.89635792 |
| 82 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.88474614 |
| 83 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.88281354 |
| 84 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.88238661 |
| 85 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.87435858 |
| 86 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.87251835 |
| 87 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.87237338 |
| 88 | Tuberculosis_Homo sapiens_hsa05152 | 0.84700036 |
| 89 | Insulin resistance_Homo sapiens_hsa04931 | 0.84589657 |
| 90 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.84384158 |
| 91 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.83738907 |
| 92 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.81592414 |
| 93 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.80834570 |
| 94 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.80785226 |
| 95 | Alcoholism_Homo sapiens_hsa05034 | 0.80401223 |
| 96 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.79981637 |
| 97 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.79664251 |
| 98 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.79331806 |
| 99 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.78464773 |
| 100 | Hepatitis B_Homo sapiens_hsa05161 | 0.77392063 |
| 101 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.77340694 |
| 102 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.75446514 |
| 103 | Pertussis_Homo sapiens_hsa05133 | 0.75352619 |
| 104 | Base excision repair_Homo sapiens_hsa03410 | 0.74103723 |
| 105 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.73588191 |
| 106 | Salmonella infection_Homo sapiens_hsa05132 | 0.73324084 |
| 107 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.73134855 |
| 108 | Shigellosis_Homo sapiens_hsa05131 | 0.72249556 |
| 109 | Lysine degradation_Homo sapiens_hsa00310 | 0.71942345 |
| 110 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.70593599 |
| 111 | Salivary secretion_Homo sapiens_hsa04970 | 0.69146343 |
| 112 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.68987925 |
| 113 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.67287367 |
| 114 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.66720562 |
| 115 | Viral myocarditis_Homo sapiens_hsa05416 | 0.66301934 |
| 116 | RNA polymerase_Homo sapiens_hsa03020 | 0.66160258 |
| 117 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.66154979 |
| 118 | Phagosome_Homo sapiens_hsa04145 | 0.65505376 |
| 119 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.65077008 |
| 120 | Renin secretion_Homo sapiens_hsa04924 | 0.62758930 |
| 121 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.62308614 |
| 122 | Mismatch repair_Homo sapiens_hsa03430 | 0.62094993 |
| 123 | Adherens junction_Homo sapiens_hsa04520 | 0.60702757 |
| 124 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.60351876 |
| 125 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60086085 |
| 126 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.59279675 |
| 127 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.59176620 |
| 128 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.58469519 |
| 129 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.58226299 |
| 130 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.55654431 |
| 131 | Malaria_Homo sapiens_hsa05144 | 0.53957401 |
| 132 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53603567 |
| 133 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.52474528 |
| 134 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.52325517 |
| 135 | Prostate cancer_Homo sapiens_hsa05215 | 0.51984113 |
| 136 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.51429991 |
| 137 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51377045 |
| 138 | HTLV-I infection_Homo sapiens_hsa05166 | 0.50885444 |
| 139 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.50468953 |
| 140 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.49883745 |
| 141 | Asthma_Homo sapiens_hsa05310 | 0.49713954 |
| 142 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.48824289 |
| 143 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.48753575 |
| 144 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.48074675 |
| 145 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.46786609 |
| 146 | Glioma_Homo sapiens_hsa05214 | 0.46699610 |

