ZBTB2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)3.96190037
2regulation of RNA export from nucleus (GO:0046831)3.84401187
3positive thymic T cell selection (GO:0045059)3.66118440
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.49644398
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.49644398
6tolerance induction (GO:0002507)3.49421984
7folic acid-containing compound biosynthetic process (GO:0009396)3.38320150
8nuclear pore complex assembly (GO:0051292)3.32295259
9negative T cell selection (GO:0043383)3.31926496
10nuclear pore organization (GO:0006999)3.26439037
11metaphase plate congression (GO:0051310)3.25676593
12N-terminal protein amino acid acetylation (GO:0006474)3.22899548
13negative thymic T cell selection (GO:0045060)3.22445375
14positive T cell selection (GO:0043368)3.20969993
15ribosome assembly (GO:0042255)3.20855898
16regulation of nucleobase-containing compound transport (GO:0032239)3.17670531
17establishment of integrated proviral latency (GO:0075713)3.16732529
18glucocorticoid receptor signaling pathway (GO:0042921)3.16061591
19regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.14108107
20protein localization to kinetochore (GO:0034501)3.14099848
21negative regulation of histone methylation (GO:0031061)3.12424361
223-UTR-mediated mRNA stabilization (GO:0070935)3.08825702
23establishment of chromosome localization (GO:0051303)3.07522817
24positive regulation of gamma-delta T cell activation (GO:0046645)3.07423244
25NIK/NF-kappaB signaling (GO:0038061)3.04508623
26mitotic nuclear envelope disassembly (GO:0007077)3.04464657
27histone H2A monoubiquitination (GO:0035518)3.04218592
28hippo signaling (GO:0035329)3.02022832
29thymic T cell selection (GO:0045061)3.01860679
30antigen processing and presentation of endogenous antigen (GO:0019883)3.00919457
31DNA strand elongation involved in DNA replication (GO:0006271)3.00210261
32germ cell migration (GO:0008354)2.99088290
33CENP-A containing nucleosome assembly (GO:0034080)2.97791837
34DNA strand elongation (GO:0022616)2.97393907
35pre-miRNA processing (GO:0031054)2.96645040
36regulation of gamma-delta T cell differentiation (GO:0045586)2.90869499
37mitotic sister chromatid cohesion (GO:0007064)2.88161254
38DNA topological change (GO:0006265)2.86245810
39DNA duplex unwinding (GO:0032508)2.85920885
40mitotic sister chromatid segregation (GO:0000070)2.85606492
41telomere maintenance via semi-conservative replication (GO:0032201)2.84228571
42nuclear envelope disassembly (GO:0051081)2.83949703
43membrane disassembly (GO:0030397)2.83949703
44DNA geometric change (GO:0032392)2.79198033
45chromatin remodeling at centromere (GO:0031055)2.78963354
46V(D)J recombination (GO:0033151)2.78810876
47T cell selection (GO:0045058)2.76590362
48regulation of posttranscriptional gene silencing (GO:0060147)2.75754810
49regulation of gene silencing by miRNA (GO:0060964)2.75754810
50regulation of gene silencing by RNA (GO:0060966)2.75754810
51protein localization to chromosome, centromeric region (GO:0071459)2.75613393
52trophectodermal cell differentiation (GO:0001829)2.72354404
53sister chromatid segregation (GO:0000819)2.71469139
54viral mRNA export from host cell nucleus (GO:0046784)2.68676803
55mRNA stabilization (GO:0048255)2.68345098
56RNA stabilization (GO:0043489)2.68345098
57regulation of centriole replication (GO:0046599)2.67817048
58negative regulation of thymocyte apoptotic process (GO:0070244)2.67565385
59corticosteroid receptor signaling pathway (GO:0031958)2.67039253
60establishment of viral latency (GO:0019043)2.65589391
61natural killer cell differentiation (GO:0001779)2.63657091
62regulation of translation in response to stress (GO:0043555)2.63373210
63establishment of endothelial barrier (GO:0061028)2.63200156
64pore complex assembly (GO:0046931)2.62102770
65positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.61606277
66embryonic process involved in female pregnancy (GO:0060136)2.59951040
67positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.59162395
68positive regulation of B cell differentiation (GO:0045579)2.58353765
69chromatin assembly (GO:0031497)2.57896023
70alternative mRNA splicing, via spliceosome (GO:0000380)2.57740428
71protein localization to endosome (GO:0036010)2.57709730
72negative regulation of chromosome segregation (GO:0051985)2.57076676
73regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.55667129
74regulation of mitotic metaphase/anaphase transition (GO:0030071)2.55667129
75positive regulation of chromosome segregation (GO:0051984)2.54644231
76negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.54488949
77regulation of mitotic spindle checkpoint (GO:1903504)2.54277278
78regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.54277278
79nuclear envelope organization (GO:0006998)2.54043076
80DNA replication-independent nucleosome assembly (GO:0006336)2.53832060
81DNA replication-independent nucleosome organization (GO:0034724)2.53832060
82regulation of T cell tolerance induction (GO:0002664)2.53478390
83negative regulation of sister chromatid segregation (GO:0033046)2.53453078
84negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.53453078
85negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.53453078
86negative regulation of mitotic sister chromatid segregation (GO:0033048)2.53453078
87negative regulation of mitotic sister chromatid separation (GO:2000816)2.53453078
88regulation of gamma-delta T cell activation (GO:0046643)2.52728072
89regulation of chromosome segregation (GO:0051983)2.52535964
90protein localization to chromosome (GO:0034502)2.50673571
91regulation of SMAD protein import into nucleus (GO:0060390)2.49891289
92dosage compensation (GO:0007549)2.49182008
93positive regulation of SMAD protein import into nucleus (GO:0060391)2.48760626
94telomere maintenance via recombination (GO:0000722)2.48430947
95positive regulation of lamellipodium assembly (GO:0010592)2.47360660
96heterochromatin organization (GO:0070828)2.47271777
97regulation of sister chromatid cohesion (GO:0007063)2.47269126
98positive regulation of tolerance induction (GO:0002645)2.46055766
99mitotic metaphase plate congression (GO:0007080)2.44659638
100negative regulation of DNA repair (GO:0045738)2.44582210
101regulation of spindle checkpoint (GO:0090231)2.43809472
102DNA ligation (GO:0006266)2.43475936
103regulation of mitotic sister chromatid separation (GO:0010965)2.43182740
104regulation of mitotic sister chromatid segregation (GO:0033047)2.43182740
105regulation of sister chromatid segregation (GO:0033045)2.43182740
106DNA replication checkpoint (GO:0000076)2.42937318
107Arp2/3 complex-mediated actin nucleation (GO:0034314)2.42502788
108cytoplasmic mRNA processing body assembly (GO:0033962)2.42086498
109monoubiquitinated protein deubiquitination (GO:0035520)2.41791414
110formation of translation preinitiation complex (GO:0001731)2.41539656
111negative regulation of necroptotic process (GO:0060546)2.40628546
112response to laminar fluid shear stress (GO:0034616)2.40357692
113negative regulation of mRNA metabolic process (GO:1903312)2.39984549
114regulation of alpha-beta T cell proliferation (GO:0046640)2.39872488
115cellular protein complex localization (GO:0034629)2.39073508
116mitotic spindle checkpoint (GO:0071174)2.38651376
117mitotic spindle assembly checkpoint (GO:0007094)2.38573026
118termination of RNA polymerase II transcription (GO:0006369)2.38038142
119hepatocyte apoptotic process (GO:0097284)2.37479338
120positive regulation of mitotic sister chromatid separation (GO:1901970)2.36572693
121positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.36572693
122positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.36572693
123nodal signaling pathway (GO:0038092)2.35668316
124protein complex localization (GO:0031503)2.35390044
125termination of RNA polymerase I transcription (GO:0006363)2.35313458
126T cell apoptotic process (GO:0070231)2.34747834
127viral transcription (GO:0019083)2.33941822
128regulation of fibroblast apoptotic process (GO:2000269)2.33636796
129negative regulation of mRNA processing (GO:0050686)2.33277807
130negative regulation of cell killing (GO:0031342)2.33175160
131negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.33175160
132spindle checkpoint (GO:0031577)2.33098197
133spindle assembly checkpoint (GO:0071173)2.32616865
134DNA replication initiation (GO:0006270)2.32425166
135morphogenesis of an endothelium (GO:0003159)2.32160928
136endothelial tube morphogenesis (GO:0061154)2.32160928
137histone exchange (GO:0043486)2.32009842
138regulation of necroptotic process (GO:0060544)2.31902076
139histone H2A ubiquitination (GO:0033522)2.31408221
140histone H3-K36 demethylation (GO:0070544)2.31008436
141mitotic recombination (GO:0006312)2.30659817
142regulation of B cell receptor signaling pathway (GO:0050855)2.29798723
143positive regulation of isotype switching (GO:0045830)2.27786867
144regulation of tolerance induction (GO:0002643)2.27289299
145ribosome biogenesis (GO:0042254)2.26930527
146regulation of mRNA stability (GO:0043488)2.26896566
147mRNA export from nucleus (GO:0006406)2.26581257
148anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.24741806
149regulation of B cell differentiation (GO:0045577)2.24619384
150chromosome segregation (GO:0007059)2.24101881
151mRNA transport (GO:0051028)2.23353617
152maturation of SSU-rRNA (GO:0030490)2.22349583
153chromatin assembly or disassembly (GO:0006333)2.22253234
154pinocytosis (GO:0006907)2.21763092
155regulation of histone H3-K9 methylation (GO:0051570)2.21527063
156angiogenesis involved in wound healing (GO:0060055)2.19277318
157translational termination (GO:0006415)2.19012377
158mitotic chromosome condensation (GO:0007076)2.18951351
159regulation of RNA stability (GO:0043487)2.18577124
160regulation of spindle organization (GO:0090224)2.18365278
161regulation of interleukin-12 biosynthetic process (GO:0045075)2.17485338
162negative regulation of RNA splicing (GO:0033119)2.17472943
163regulation of histone H3-K27 methylation (GO:0061085)2.17462741
164mRNA cleavage (GO:0006379)2.16636398
165regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.16181361
166positive regulation of lamellipodium organization (GO:1902745)2.14454772
167regulation of histone methylation (GO:0031060)2.13835277
168lymphocyte apoptotic process (GO:0070227)2.13575209

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.40151312
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.57457613
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.95225262
4MYC_22102868_ChIP-Seq_BL_Human3.47155822
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.46822708
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.22522500
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.91961786
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.62663333
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.54219489
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.53650830
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.32132850
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.29833734
13MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.28382012
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.27079407
15VDR_21846776_ChIP-Seq_THP-1_Human2.24367441
16* TCF7_22412390_ChIP-Seq_EML_Mouse2.11674611
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.05432128
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.04587730
19MYC_19079543_ChIP-ChIP_MESCs_Mouse1.97222768
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.95823961
21NOTCH1_21737748_ChIP-Seq_TLL_Human1.93998952
22DCP1A_22483619_ChIP-Seq_HELA_Human1.90219465
23MAF_26560356_Chip-Seq_TH1_Human1.87478682
24CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.86123637
25EST1_17652178_ChIP-ChIP_JURKAT_Human1.80675086
26JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.77029843
27CIITA_25753668_ChIP-Seq_RAJI_Human1.76932792
28TP63_19390658_ChIP-ChIP_HaCaT_Human1.76232017
29MYB_26560356_Chip-Seq_TH2_Human1.75437632
30KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.75236375
31MYB_21317192_ChIP-Seq_ERMYB_Mouse1.73800908
32E2F1_21310950_ChIP-Seq_MCF-7_Human1.73685523
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.72143387
34ETS1_20019798_ChIP-Seq_JURKAT_Human1.71316705
35KDM2B_26808549_Chip-Seq_DND41_Human1.69666570
36UTX_26944678_Chip-Seq_JUKART_Human1.68563629
37HOXB4_20404135_ChIP-ChIP_EML_Mouse1.67611312
38ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.65832372
39KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.64762354
40FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.64634352
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64406088
42MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.61543852
43AR_21909140_ChIP-Seq_LNCAP_Human1.61409768
44MYC_19030024_ChIP-ChIP_MESCs_Mouse1.58786683
45SCL_19346495_ChIP-Seq_HPC-7_Human1.58506682
46NELFA_20434984_ChIP-Seq_ESCs_Mouse1.56583441
47KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.54868805
48SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53890719
49ELK3_25401928_ChIP-Seq_HUVEC_Human1.52200082
50MYB_26560356_Chip-Seq_TH1_Human1.51597407
51STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.51093046
52IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.48794313
53KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.45937263
54KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.45474262
55KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.45474262
56KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.45474262
57PADI4_21655091_ChIP-ChIP_MCF-7_Human1.45275495
58NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.43910192
59SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.43085914
60YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.41976841
61* GABP_19822575_ChIP-Seq_HepG2_Human1.41613389
62XRN2_22483619_ChIP-Seq_HELA_Human1.41138323
63ELK1_19687146_ChIP-ChIP_HELA_Human1.40412072
64RUNX_20019798_ChIP-Seq_JUKART_Human1.40375405
65ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.39433467
66KDM2B_26808549_Chip-Seq_SUP-B15_Human1.36072625
67VDR_24763502_ChIP-Seq_THP-1_Human1.35383793
68* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.34212756
69SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.34206281
70ERG_20887958_ChIP-Seq_HPC-7_Mouse1.33625643
71KLF4_18555785_ChIP-Seq_MESCs_Mouse1.32016371
72PKCTHETA_26484144_Chip-Seq_BREAST_Human1.30625308
73RUNX1_22412390_ChIP-Seq_EML_Mouse1.30203171
74THAP11_20581084_ChIP-Seq_MESCs_Mouse1.29378175
75TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.28816480
76* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.27364056
77PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.26197129
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.25647535
79FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.25378688
80TP63_17297297_ChIP-ChIP_HaCaT_Human1.23962006
81* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.22252475
82MYCN_18555785_ChIP-Seq_MESCs_Mouse1.20966478
83CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.20715093
84KDM5A_27292631_Chip-Seq_BREAST_Human1.20356071
85MAF_26560356_Chip-Seq_TH2_Human1.20190282
86* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.19857229
87POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.19841160
88CLOCK_20551151_ChIP-Seq_293T_Human1.19571152
89* KDM2B_26808549_Chip-Seq_JURKAT_Human1.19541212
90CHD1_26751641_Chip-Seq_LNCaP_Human1.19178908
91* NCOR1_26117541_ChIP-Seq_K562_Human1.18189330
92SPI1_23547873_ChIP-Seq_NB4_Human1.17916347
93MYC_18358816_ChIP-ChIP_MESCs_Mouse1.17438933
94TCF3_18692474_ChIP-Seq_MEFs_Mouse1.17367720
95PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17085196
96HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.17021786
97E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.15604953
98IRF8_22096565_ChIP-ChIP_GC-B_Human1.14590077
99NANOG_18555785_ChIP-Seq_MESCs_Mouse1.14559594
100TFEB_21752829_ChIP-Seq_HELA_Human1.14514711
101SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.13200279
102* NANOG_21062744_ChIP-ChIP_HESCs_Human1.12337410
103* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.12153719
104* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.12138583
105GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.12034777
106STAT6_21828071_ChIP-Seq_BEAS2B_Human1.11111722
107TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.10969576
108CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.10794413
109TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08865054
110* ATF3_27146783_Chip-Seq_COLON_Human1.07860844
111SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.07815978
112IRF8_21731497_ChIP-ChIP_J774_Mouse1.07126605
113SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.06986852
114TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06629411
115KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.06106148
116SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.05581857
117BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.03917997
118MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.01783990
119SALL1_21062744_ChIP-ChIP_HESCs_Human1.01647830
120STAT4_19710469_ChIP-ChIP_TH1__Mouse1.01032611
121BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.00541111
122VDR_23849224_ChIP-Seq_CD4+_Human1.00469233
123CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.00221024
124P300_27058665_Chip-Seq_ZR-75-30cells_Human0.99346597
125E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.98228953
126RBPJ_22232070_ChIP-Seq_NCS_Mouse0.97708849
127ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.96306800
128FOXP3_21729870_ChIP-Seq_TREG_Human0.96105580
129TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.94569619
130STAT3_1855785_ChIP-Seq_MESCs_Mouse0.94555250
131YY1_21170310_ChIP-Seq_MESCs_Mouse0.94527038
132POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.94006898
133* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.93479311
134TTF2_22483619_ChIP-Seq_HELA_Human0.93401966
135HIF1A_21447827_ChIP-Seq_MCF-7_Human0.93297060
136NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.92040720
137CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.91827756
138NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.91116302

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system3.21201756
2MP0010352_gastrointestinal_tract_polyps2.64362661
3MP0003693_abnormal_embryo_hatching2.58207244
4MP0003763_abnormal_thymus_physiology2.39193929
5MP0010094_abnormal_chromosome_stability2.33629837
6MP0004808_abnormal_hematopoietic_stem2.20577339
7MP0005076_abnormal_cell_differentiation2.19341536
8MP0004957_abnormal_blastocyst_morpholog2.18620539
9MP0003111_abnormal_nucleus_morphology2.18025403
10MP0003077_abnormal_cell_cycle2.17883153
11MP0008057_abnormal_DNA_replication2.06915220
12MP0005451_abnormal_body_composition2.06627505
13MP0003300_gastrointestinal_ulcer2.05987074
14MP0003303_peritoneal_inflammation2.04944503
15MP0006054_spinal_hemorrhage1.91040487
16MP0010234_abnormal_vibrissa_follicle1.90712421
17MP0009278_abnormal_bone_marrow1.87238264
18MP0002877_abnormal_melanocyte_morpholog1.82593866
19MP0003123_paternal_imprinting1.80440231
20MP0000703_abnormal_thymus_morphology1.78106780
21MP0000350_abnormal_cell_proliferation1.76242625
22MP0002398_abnormal_bone_marrow1.74652741
23MP0000685_abnormal_immune_system1.73962861
24MP0001730_embryonic_growth_arrest1.69061981
25MP0002796_impaired_skin_barrier1.67562877
26MP0001800_abnormal_humoral_immune1.64172209
27MP0001853_heart_inflammation1.60602562
28MP0010307_abnormal_tumor_latency1.57670292
29MP0000490_abnormal_crypts_of1.56686157
30MP0000537_abnormal_urethra_morphology1.55901454
31MP0003786_premature_aging1.53474168
32MP0003705_abnormal_hypodermis_morpholog1.52691749
33MP0008260_abnormal_autophagy1.52168753
34MP0008877_abnormal_DNA_methylation1.51915221
35MP0002088_abnormal_embryonic_growth/wei1.50246048
36MP0003984_embryonic_growth_retardation1.50027626
37MP0002722_abnormal_immune_system1.47075673
38MP0001697_abnormal_embryo_size1.46891122
39MP0002166_altered_tumor_susceptibility1.46470359
40MP0000689_abnormal_spleen_morphology1.44104698
41MP0002452_abnormal_antigen_presenting1.43521571
42MP0001672_abnormal_embryogenesis/_devel1.43269851
43MP0005380_embryogenesis_phenotype1.43269851
44MP0002086_abnormal_extraembryonic_tissu1.42448461
45MP0002084_abnormal_developmental_patter1.40901986
46MP0005023_abnormal_wound_healing1.40763342
47MP0005671_abnormal_response_to1.40004096
48MP0003718_maternal_effect1.38239772
49MP0003566_abnormal_cell_adhesion1.37821276
50MP0000716_abnormal_immune_system1.34452065
51MP0002138_abnormal_hepatobiliary_system1.34380290
52MP0003941_abnormal_skin_development1.33457616
53MP0002420_abnormal_adaptive_immunity1.33450706
54MP0005397_hematopoietic_system_phenotyp1.32353838
55MP0001545_abnormal_hematopoietic_system1.32353838
56MP0002019_abnormal_tumor_incidence1.32153456
57MP0009333_abnormal_splenocyte_physiolog1.31926514
58MP0002405_respiratory_system_inflammati1.31633835
59MP0001819_abnormal_immune_cell1.31613558
60MP0008007_abnormal_cellular_replicative1.30332407
61MP0002429_abnormal_blood_cell1.25452009
62MP0002085_abnormal_embryonic_tissue1.24655861
63MP0002723_abnormal_immune_serum1.23724292
64MP0008995_early_reproductive_senescence1.23276726
65MP0001915_intracranial_hemorrhage1.22812733
66MP0001835_abnormal_antigen_presentation1.22086290
67MP0005501_abnormal_skin_physiology1.21162638
68MP0008058_abnormal_DNA_repair1.20634147
69MP0003890_abnormal_embryonic-extraembry1.19629457
70MP0000733_abnormal_muscle_development1.19326391
71MP0008932_abnormal_embryonic_tissue1.17068335
72MP0002080_prenatal_lethality1.16710595
73MP0004185_abnormal_adipocyte_glucose1.16667718
74MP0001727_abnormal_embryo_implantation1.15510506
75MP0004233_abnormal_muscle_weight1.13917406
76MP0003121_genomic_imprinting1.13506412
77MP0003091_abnormal_cell_migration1.13145544
78MP0009672_abnormal_birth_weight1.12995009
79MP0005310_abnormal_salivary_gland1.12267862
80MP0000858_altered_metastatic_potential1.11631271
81MP0004381_abnormal_hair_follicle1.09319015
82MP0005387_immune_system_phenotype1.08809544
83MP0001790_abnormal_immune_system1.08809544
84MP0004197_abnormal_fetal_growth/weight/1.08560083
85MP0004947_skin_inflammation1.07795724
86MP0005025_abnormal_response_to1.06287292
87MP0003221_abnormal_cardiomyocyte_apopto1.05047552
88MP0002925_abnormal_cardiovascular_devel1.02030815
89MP0000313_abnormal_cell_death1.01205987
90MP0005000_abnormal_immune_tolerance1.00279924
91MP0003828_pulmonary_edema0.99930615
92MP0000767_abnormal_smooth_muscle0.99439186
93MP0001293_anophthalmia0.99282840
94MP0002419_abnormal_innate_immunity0.98079901
95MP0003453_abnormal_keratinocyte_physiol0.96827741
96MP0005075_abnormal_melanosome_morpholog0.95922262
97MP0008961_abnormal_basal_metabolism0.95466631
98MP0001879_abnormal_lymphatic_vessel0.95146475
99MP0009053_abnormal_anal_canal0.93544920
100MP0002006_tumorigenesis0.93076326
101MP0009785_altered_susceptibility_to0.92933906
102MP0010155_abnormal_intestine_physiology0.92209533
103MP0009384_cardiac_valve_regurgitation0.91414441
104MP0003448_altered_tumor_morphology0.89060377
105MP0002148_abnormal_hypersensitivity_rea0.88307147
106MP0002933_joint_inflammation0.88016402
107MP0000516_abnormal_urinary_system0.87863134
108MP0005367_renal/urinary_system_phenotyp0.87863134
109MP0003436_decreased_susceptibility_to0.85054684
110MP0010030_abnormal_orbit_morphology0.84955980
111MP0002092_abnormal_eye_morphology0.84553352
112MP0005621_abnormal_cell_physiology0.83088744
113MP0003943_abnormal_hepatobiliary_system0.82885759
114MP0008789_abnormal_olfactory_epithelium0.82268438
115MP0003950_abnormal_plasma_membrane0.81384815
116MP0006035_abnormal_mitochondrial_morpho0.80551084
117MP0005384_cellular_phenotype0.80328905
118MP0001873_stomach_inflammation0.79898378
119MP0004264_abnormal_extraembryonic_tissu0.79665479
120MP0002009_preneoplasia0.77074284
121MP0000477_abnormal_intestine_morphology0.76051116
122MP0002111_abnormal_tail_morphology0.75713293
123MP0001845_abnormal_inflammatory_respons0.75653119
124MP0006082_CNS_inflammation0.73589566
125MP0005464_abnormal_platelet_physiology0.72954348
126MP0002210_abnormal_sex_determination0.72474708
127MP0001216_abnormal_epidermal_layer0.72408623

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)3.54559597
2IgM deficiency (HP:0002850)3.28840159
3Chromsome breakage (HP:0040012)3.20855220
4Volvulus (HP:0002580)3.07424938
5Increased density of long bones (HP:0006392)3.01942790
6Abnormal number of incisors (HP:0011064)2.96155793
7T lymphocytopenia (HP:0005403)2.96103927
8Abnormality of the fingertips (HP:0001211)2.91599052
9Degeneration of anterior horn cells (HP:0002398)2.88772651
10Abnormality of the anterior horn cell (HP:0006802)2.88772651
11Abnormality of T cell number (HP:0011839)2.77164388
12Syringomyelia (HP:0003396)2.69286261
13Spinal cord lesions (HP:0100561)2.69286261
14Selective tooth agenesis (HP:0001592)2.68271492
15Prominent nose (HP:0000448)2.66466722
16Nephroblastoma (Wilms tumor) (HP:0002667)2.66414376
17Aortic aneurysm (HP:0004942)2.63039605
18Deviation of the thumb (HP:0009603)2.62973694
19Asymmetry of the thorax (HP:0001555)2.59218297
20Proximal placement of thumb (HP:0009623)2.57536632
21Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.55245850
22Short 4th metacarpal (HP:0010044)2.55245850
23Viral hepatitis (HP:0006562)2.54957332
24Urethral obstruction (HP:0000796)2.54443536
25Aplastic anemia (HP:0001915)2.52924188
26Progressive external ophthalmoplegia (HP:0000590)2.51375458
27Microvesicular hepatic steatosis (HP:0001414)2.48641483
28Premature ovarian failure (HP:0008209)2.48611755
29Recurrent viral infections (HP:0004429)2.46808657
30Recurrent abscess formation (HP:0002722)2.45403465
31Embryonal renal neoplasm (HP:0011794)2.44869767
32Pelvic girdle muscle weakness (HP:0003749)2.42568108
33Multiple enchondromatosis (HP:0005701)2.40803018
34Bicuspid aortic valve (HP:0001647)2.37274765
35Recurrent bacterial skin infections (HP:0005406)2.35121632
36Verrucae (HP:0200043)2.34944449
37Papilloma (HP:0012740)2.34944449
38Spinal muscular atrophy (HP:0007269)2.33277314
39Cutaneous melanoma (HP:0012056)2.29157563
40Cellulitis (HP:0100658)2.28956641
41B lymphocytopenia (HP:0010976)2.28303923
42Abnormality of B cell number (HP:0010975)2.28303923
43Subacute progressive viral hepatitis (HP:0006572)2.27551370
44Persistence of primary teeth (HP:0006335)2.27464463
45Protrusio acetabuli (HP:0003179)2.26461255
46Agammaglobulinemia (HP:0004432)2.25626025
47Micronodular cirrhosis (HP:0001413)2.22990406
48High pitched voice (HP:0001620)2.20743935
49Overlapping toe (HP:0001845)2.19301283
50Myelodysplasia (HP:0002863)2.18165425
51Macroorchidism (HP:0000053)2.14766692
52Abnormality of the pancreatic islet cells (HP:0006476)2.13876087
53Abnormality of endocrine pancreas physiology (HP:0012093)2.13876087
54Carpal bone hypoplasia (HP:0001498)2.13844700
55Meningitis (HP:0001287)2.13531320
56Osteomyelitis (HP:0002754)2.12338147
57Encephalitis (HP:0002383)2.11935259
58IgA deficiency (HP:0002720)2.09764750
59Ependymoma (HP:0002888)2.08849074
60Acute myeloid leukemia (HP:0004808)2.07988773
61Hematochezia (HP:0002573)2.05697841
62Eczematoid dermatitis (HP:0000976)2.04802913
63Abnormality of chromosome stability (HP:0003220)2.03528617
64Trismus (HP:0000211)2.03524766
65Basal cell carcinoma (HP:0002671)2.02736325
66Abnormality of the musculature of the pelvis (HP:0001469)2.02572567
67Abnormality of the hip-girdle musculature (HP:0001445)2.02572567
68Thyroiditis (HP:0100646)2.01072519
69Single umbilical artery (HP:0001195)1.99942400
70Abnormality of the fetal cardiovascular system (HP:0010948)1.99942400
71Abnormal umbilical cord blood vessels (HP:0011403)1.99942400
72Gonadotropin excess (HP:0000837)1.99797332
73Recurrent fungal infections (HP:0002841)1.98774810
74Abnormality of T cells (HP:0002843)1.98497806
75Papillary thyroid carcinoma (HP:0002895)1.97994347
76Cerebral aneurysm (HP:0004944)1.97881408
77Combined immunodeficiency (HP:0005387)1.97527372
78Abnormal lung lobation (HP:0002101)1.97513274
79Abnormality of the preputium (HP:0100587)1.95417874
80Cutis marmorata (HP:0000965)1.94961551
81Eosinophilia (HP:0001880)1.94934588
82Blepharitis (HP:0000498)1.94495256
83Recurrent bronchitis (HP:0002837)1.94279982
84Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.94113937
85Birth length less than 3rd percentile (HP:0003561)1.93249978
86Lower limb hyperreflexia (HP:0002395)1.92692345
87Autoimmune hemolytic anemia (HP:0001890)1.92655468
88Disproportionate tall stature (HP:0001519)1.92498429
89Increased nuchal translucency (HP:0010880)1.92245095
90Abnormal delayed hypersensitivity skin test (HP:0002963)1.92016774
91Abnormal foot bone ossification (HP:0010675)1.91568777
92Microglossia (HP:0000171)1.91240289
93Renal cell carcinoma (HP:0005584)1.90903349
94Medulloblastoma (HP:0002885)1.88680314
95Poikiloderma (HP:0001029)1.88372181
96Abnormality of the umbilical cord (HP:0010881)1.87563254
97Severe combined immunodeficiency (HP:0004430)1.87559568
98Lymphoma (HP:0002665)1.86652862
99Leiomyosarcoma (HP:0100243)1.84861094
100Uterine leiomyosarcoma (HP:0002891)1.84861094
101Stomatitis (HP:0010280)1.84750179
102Tongue fasciculations (HP:0001308)1.84644548
103Facial hemangioma (HP:0000329)1.84638912
104Limb-girdle muscle atrophy (HP:0003797)1.83894098
105Dislocated radial head (HP:0003083)1.83707838
106Shoulder girdle muscle weakness (HP:0003547)1.82798539
107Transitional cell carcinoma of the bladder (HP:0006740)1.82728967
108Abnormality of macrophages (HP:0004311)1.82702711
109Gastrointestinal carcinoma (HP:0002672)1.82454408
110Malignant gastrointestinal tract tumors (HP:0006749)1.82454408
111Skin tags (HP:0010609)1.81288047
112Abnormality of eosinophils (HP:0001879)1.80700248
113Thyroid carcinoma (HP:0002890)1.80552672
114Long eyelashes (HP:0000527)1.78756220
115IgG deficiency (HP:0004315)1.78613586
116Limited elbow extension (HP:0001377)1.77676485
117Cellular immunodeficiency (HP:0005374)1.76628139
118Myositis (HP:0100614)1.76283362
119Reduced antithrombin III activity (HP:0001976)1.75708228
120Colon cancer (HP:0003003)1.75403318
121Abnormality of T cell physiology (HP:0011840)1.74822522
122Mitral valve prolapse (HP:0001634)1.74608781
123Abnormal platelet volume (HP:0011876)1.74452718
124Low anterior hairline (HP:0000294)1.74202310
125Squamous cell carcinoma (HP:0002860)1.74116916
126Abnormality of the radial head (HP:0003995)1.74077638
127Septate vagina (HP:0001153)1.74041560
128Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.73597914
129Cafe-au-lait spot (HP:0000957)1.73474035
130Capillary hemangiomas (HP:0005306)1.73419240
131Pustule (HP:0200039)1.73172285
132Breast carcinoma (HP:0003002)1.72934089
133Progressive muscle weakness (HP:0003323)1.72884127
134Exostoses (HP:0100777)1.72384337
135Angiofibromas (HP:0010615)1.72112591
136Adenoma sebaceum (HP:0009720)1.72112591
137Acute hepatic failure (HP:0006554)1.71972477
138Neoplasm of the oral cavity (HP:0100649)1.70806879
139Abnormality of cells of the lymphoid lineage (HP:0012140)1.70376182
140Atresia of the external auditory canal (HP:0000413)1.69677809
141Abnormality of the 4th metacarpal (HP:0010012)1.69459702
142Abnormality of the phalanges of the hallux (HP:0010057)1.68768244
143Muscle fibrillation (HP:0010546)1.68066532
144Leukocytosis (HP:0001974)1.67189157
145Vertebral clefting (HP:0008428)1.64533910
146Heterotopia (HP:0002282)1.63909093
147Deep philtrum (HP:0002002)1.61384273
148Short nail (HP:0001799)1.60537742
149Trigonocephaly (HP:0000243)1.57674789
150Preauricular skin tag (HP:0000384)1.57134096
151Fibrous tissue neoplasm (HP:0012316)1.56368456
152Lymphopenia (HP:0001888)1.55774307
153Panhypogammaglobulinemia (HP:0003139)1.55325908
154Small epiphyses (HP:0010585)1.55138947
155Astrocytoma (HP:0009592)1.53188162
156Abnormality of the astrocytes (HP:0100707)1.53188162
157Abnormality of cells of the erythroid lineage (HP:0012130)1.52737412
158Fibroma (HP:0010614)1.52511558
159Mediastinal lymphadenopathy (HP:0100721)1.52456613
160Granulocytopenia (HP:0001913)1.52386991
161Supernumerary spleens (HP:0009799)1.50420454
162Spondylolisthesis (HP:0003302)1.50196611
163Dilatation of the ascending aorta (HP:0005111)1.49596941

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K103.60797456
2STK103.50857212
3MAP4K13.28991976
4STK33.09452113
5PRPF4B2.83646926
6PKN22.67992773
7EEF2K2.60708856
8TRIB32.35226864
9TRIM282.22271823
10STK242.09389335
11CDK122.06414671
12LRRK21.99390936
13IRAK41.90794585
14CDC71.88646245
15DMPK1.80652978
16GRK61.68604369
17CDK41.67155011
18IRAK31.62252992
19RPS6KA41.54361425
20EPHA31.52796917
21PIM11.52664334
22NEK21.50688446
23ITK1.50520008
24CDK61.47719887
25TXK1.46473017
26PIM21.41858074
27VRK21.38275645
28SMG11.36946728
29MST41.35788362
30TGFBR21.34883230
31TAOK21.34876460
32MUSK1.33969709
33ZAP701.33614563
34MKNK21.26857619
35PTK61.24479224
36TTK1.22419000
37JAK31.20161451
38MAP3K81.19615869
39TAF11.16312318
40SIK31.16033857
41ALK1.14843872
42MAP3K111.14389478
43TGFBR11.13857895
44PASK1.11147708
45ERN11.11104151
46CLK11.09004999
47TYK21.08373132
48MATK1.06240828
49CDK91.05158991
50TBK11.04788780
51MARK31.04360269
52IRAK21.04254299
53STK41.01849257
54MTOR1.01191001
55FGFR41.00201544
56RIPK10.99756311
57MAP2K30.99554058
58IRAK10.97669376
59BUB10.97383364
60MAP3K130.97035607
61NEK10.95304723
62PLK40.94450526
63MKNK10.92567913
64TESK20.91405665
65RPS6KB20.91084023
66KDR0.89706834
67RIPK40.86668611
68BTK0.85508771
69KSR10.84995870
70MELK0.84264837
71MAP3K140.83808217
72EIF2AK20.83732473
73NLK0.83349297
74CDK70.83208533
75YES10.83108971
76CSF1R0.82076918
77CHUK0.81044175
78MAP3K30.80812944
79BRD40.80610057
80PBK0.78497527
81LATS10.77659966
82EPHA20.77236859
83SIK10.77151638
84FGFR30.76905323
85ERBB40.76350550
86WEE10.74483009
87TAOK10.74029538
88CDK80.73356492
89CSK0.73207006
90DYRK30.71125447
91FLT30.71015985
92PLK10.70676666
93ATR0.70586047
94RAF10.70575174
95BRSK10.69584446
96PAK40.69541598
97TAOK30.68001398
98SCYL20.67864632
99SIK20.67238645
100JAK10.66227395
101CHEK10.66207191
102MAP3K50.65885810
103KSR20.65845518
104LATS20.61678256
105ARAF0.61234560
106ACVR1B0.61178326
107PLK30.61077471
108ZAK0.60829428
109HCK0.60427857
110HIPK20.60404956
111EIF2AK10.57588806
112MAP3K120.57309227
113CDK20.56782977
114LCK0.56427076
115KIT0.56159622
116MAP2K20.55807642
117PNCK0.55395242
118IKBKE0.54259224
119EIF2AK30.53765493
120NME10.53721981
121AURKB0.53379312
122TRPM70.53188393
123FGFR10.52980927
124NEK60.52696291
125BRSK20.51194207
126MAPKAPK30.51112346
127CHEK20.50661869
128AURKA0.49872155
129VRK10.49366368
130PTK20.48349661
131NME20.46566992
132SRPK10.45182655
133IKBKB0.44769861
134TTN0.43598357
135ICK0.43589598
136PRKCQ0.42914430
137SYK0.42776906
138EPHB10.40579128
139TSSK60.40505839
140PDGFRB0.39763027

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030502.43868943
2Cell cycle_Homo sapiens_hsa041102.30654170
3DNA replication_Homo sapiens_hsa030302.13235467
4Primary immunodeficiency_Homo sapiens_hsa053401.99411192
5Chronic myeloid leukemia_Homo sapiens_hsa052201.95760340
6Spliceosome_Homo sapiens_hsa030401.94326990
7B cell receptor signaling pathway_Homo sapiens_hsa046621.87315151
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.85577310
9Antigen processing and presentation_Homo sapiens_hsa046121.80264083
10Colorectal cancer_Homo sapiens_hsa052101.73627756
11RNA transport_Homo sapiens_hsa030131.71963580
12MicroRNAs in cancer_Homo sapiens_hsa052061.67774081
13T cell receptor signaling pathway_Homo sapiens_hsa046601.67560622
14Acute myeloid leukemia_Homo sapiens_hsa052211.63019894
15NF-kappa B signaling pathway_Homo sapiens_hsa040641.62981033
16Small cell lung cancer_Homo sapiens_hsa052221.60055494
17Pancreatic cancer_Homo sapiens_hsa052121.53885158
18Hepatitis B_Homo sapiens_hsa051611.50641063
19Base excision repair_Homo sapiens_hsa034101.50204134
20p53 signaling pathway_Homo sapiens_hsa041151.47684103
21Viral carcinogenesis_Homo sapiens_hsa052031.47296293
22Apoptosis_Homo sapiens_hsa042101.45871046
23Measles_Homo sapiens_hsa051621.43748054
24Adherens junction_Homo sapiens_hsa045201.40546263
25Epstein-Barr virus infection_Homo sapiens_hsa051691.39309416
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.38459331
27Herpes simplex infection_Homo sapiens_hsa051681.38172365
28Hippo signaling pathway_Homo sapiens_hsa043901.37965915
29Viral myocarditis_Homo sapiens_hsa054161.37942249
30Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.37918758
31HTLV-I infection_Homo sapiens_hsa051661.36970353
32Notch signaling pathway_Homo sapiens_hsa043301.36299189
33Osteoclast differentiation_Homo sapiens_hsa043801.36156401
34mRNA surveillance pathway_Homo sapiens_hsa030151.34725620
35One carbon pool by folate_Homo sapiens_hsa006701.31487128
36Endometrial cancer_Homo sapiens_hsa052131.26991435
37Transcriptional misregulation in cancer_Homo sapiens_hsa052021.26915309
38Mismatch repair_Homo sapiens_hsa034301.25899486
39Leukocyte transendothelial migration_Homo sapiens_hsa046701.25240045
40Shigellosis_Homo sapiens_hsa051311.25094009
41Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23401694
42Thyroid cancer_Homo sapiens_hsa052161.21722525
43Pyrimidine metabolism_Homo sapiens_hsa002401.17564615
44Allograft rejection_Homo sapiens_hsa053301.15774440
45Toxoplasmosis_Homo sapiens_hsa051451.14827982
46AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.14417952
47Leishmaniasis_Homo sapiens_hsa051401.13175520
48Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.10159228
49TGF-beta signaling pathway_Homo sapiens_hsa043501.09617869
50Non-small cell lung cancer_Homo sapiens_hsa052231.08970881
51Autoimmune thyroid disease_Homo sapiens_hsa053201.08410440
52Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.07417672
53Intestinal immune network for IgA production_Homo sapiens_hsa046721.06674021
54Homologous recombination_Homo sapiens_hsa034401.05783443
55Prostate cancer_Homo sapiens_hsa052151.04698316
56Proteoglycans in cancer_Homo sapiens_hsa052051.03996820
57Ribosome_Homo sapiens_hsa030101.00648531
58Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.00064491
59FoxO signaling pathway_Homo sapiens_hsa040680.98093488
60Renal cell carcinoma_Homo sapiens_hsa052110.97216503
61Neurotrophin signaling pathway_Homo sapiens_hsa047220.96975753
62TNF signaling pathway_Homo sapiens_hsa046680.94342034
63Non-homologous end-joining_Homo sapiens_hsa034500.93373684
64Lysine degradation_Homo sapiens_hsa003100.90835842
65VEGF signaling pathway_Homo sapiens_hsa043700.90189569
66Graft-versus-host disease_Homo sapiens_hsa053320.89928389
67RNA degradation_Homo sapiens_hsa030180.88109142
68RNA polymerase_Homo sapiens_hsa030200.86384876
69mTOR signaling pathway_Homo sapiens_hsa041500.86028140
70NOD-like receptor signaling pathway_Homo sapiens_hsa046210.85982830
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.85038301
72Basal cell carcinoma_Homo sapiens_hsa052170.84968772
73Pathways in cancer_Homo sapiens_hsa052000.84417932
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.83887575
75Jak-STAT signaling pathway_Homo sapiens_hsa046300.83866422
76Focal adhesion_Homo sapiens_hsa045100.82651145
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82194810
78Hematopoietic cell lineage_Homo sapiens_hsa046400.82183804
79Toll-like receptor signaling pathway_Homo sapiens_hsa046200.82087559
80Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.81728186
81Nucleotide excision repair_Homo sapiens_hsa034200.80906526
82Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.80792163
83Legionellosis_Homo sapiens_hsa051340.79364678
84Influenza A_Homo sapiens_hsa051640.78236634
85Bladder cancer_Homo sapiens_hsa052190.78024071
86Platelet activation_Homo sapiens_hsa046110.75282213
87Chemokine signaling pathway_Homo sapiens_hsa040620.75170965
88Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.73935156
89Prolactin signaling pathway_Homo sapiens_hsa049170.72708528
90Regulation of actin cytoskeleton_Homo sapiens_hsa048100.72691138
91Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.72208131
92Type I diabetes mellitus_Homo sapiens_hsa049400.69536392
93Wnt signaling pathway_Homo sapiens_hsa043100.68522094
94Basal transcription factors_Homo sapiens_hsa030220.67083034
95Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.65007344
96Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.64775721
97PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62365598
98RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.62339568
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.62106034
100Glioma_Homo sapiens_hsa052140.61441600
101Oocyte meiosis_Homo sapiens_hsa041140.60471162
102Tuberculosis_Homo sapiens_hsa051520.59689149
103Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.59010984
104Hepatitis C_Homo sapiens_hsa051600.58610035
105Fanconi anemia pathway_Homo sapiens_hsa034600.58503439
106Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.57299084
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.56572495
108Rap1 signaling pathway_Homo sapiens_hsa040150.56473934
109MAPK signaling pathway_Homo sapiens_hsa040100.56343490
110SNARE interactions in vesicular transport_Homo sapiens_hsa041300.51135086
111Protein export_Homo sapiens_hsa030600.48946169
112Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48618369
113Sphingolipid signaling pathway_Homo sapiens_hsa040710.46896820
114Purine metabolism_Homo sapiens_hsa002300.46149210
115Longevity regulating pathway - mammal_Homo sapiens_hsa042110.44916635
116Folate biosynthesis_Homo sapiens_hsa007900.43777294
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.43578199

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