ZBTB26

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)5.97264472
2mitotic sister chromatid cohesion (GO:0007064)5.75010517
3centrosome duplication (GO:0051298)5.45146677
4male meiosis I (GO:0007141)5.07371486
5response to UV-C (GO:0010225)4.91527918
6cell differentiation involved in metanephros development (GO:0072202)4.79948217
7gonadal mesoderm development (GO:0007506)4.65032971
8protein localization to kinetochore (GO:0034501)4.64993337
9DNA replication checkpoint (GO:0000076)4.58606396
10histone H4-K5 acetylation (GO:0043981)4.52815251
11histone H4-K8 acetylation (GO:0043982)4.52815251
12sister chromatid cohesion (GO:0007062)4.47932745
13mesenchymal cell differentiation involved in kidney development (GO:0072161)4.44714637
14mesenchymal cell differentiation involved in renal system development (GO:2001012)4.44714637
15regulation of NFAT protein import into nucleus (GO:0051532)4.35979900
16DNA replication-dependent nucleosome assembly (GO:0006335)4.24930320
17DNA replication-dependent nucleosome organization (GO:0034723)4.24930320
18histone H4-K12 acetylation (GO:0043983)4.16199093
19glomerulus development (GO:0032835)4.14622937
20meiosis I (GO:0007127)4.04072665
21histone H4-K16 acetylation (GO:0043984)4.03356204
22histone H2A acetylation (GO:0043968)3.90703928
23inner cell mass cell proliferation (GO:0001833)3.89882374
24DNA dealkylation (GO:0035510)3.88170125
25histone H4 acetylation (GO:0043967)3.88151568
26response to lipoprotein particle (GO:0055094)3.87534374
27mitotic G2 DNA damage checkpoint (GO:0007095)3.86753729
28centrosome organization (GO:0051297)3.75717680
29oocyte maturation (GO:0001556)3.72516629
30definitive hemopoiesis (GO:0060216)3.67628453
31positive regulation of mRNA processing (GO:0050685)3.67407503
32protein localization to chromosome, centromeric region (GO:0071459)3.67402985
33positive regulation of RNA splicing (GO:0033120)3.64432131
34mitotic G2/M transition checkpoint (GO:0044818)3.62590540
35regulation of male gonad development (GO:2000018)3.59922771
36IMP biosynthetic process (GO:0006188)3.52649024
37metaphase plate congression (GO:0051310)3.51510042
38ventricular cardiac muscle cell development (GO:0055015)3.51471236
39replicative senescence (GO:0090399)3.50854611
40DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla3.50536704
41negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.49568195
42regulation of alternative mRNA splicing, via spliceosome (GO:0000381)3.49409548
43presynaptic membrane assembly (GO:0097105)3.49162609
44positive regulation of male gonad development (GO:2000020)3.47930416
45microtubule organizing center organization (GO:0031023)3.47182207
46kinetochore organization (GO:0051383)3.46474817
47protein localization to chromosome (GO:0034502)3.44732460
48regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.44282835
49DNA packaging (GO:0006323)3.43557240
50kinetochore assembly (GO:0051382)3.39714015
51arginine catabolic process (GO:0006527)3.39118065
52negative regulation of DNA recombination (GO:0045910)3.37423867
53mitochondrial RNA metabolic process (GO:0000959)3.36246891
54positive regulation of mRNA metabolic process (GO:1903313)3.35722429
55DNA topological change (GO:0006265)3.33002431
56thalamus development (GO:0021794)3.32120457
57negative regulation of mRNA processing (GO:0050686)3.29804661
58viral mRNA export from host cell nucleus (GO:0046784)3.27522115
59DNA damage response, signal transduction resulting in transcription (GO:0042772)3.25989132
60regulation of centriole replication (GO:0046599)3.24731105
61mitotic metaphase plate congression (GO:0007080)3.24191632
62regulation of establishment of cell polarity (GO:2000114)3.22264100
63adenosine metabolic process (GO:0046085)3.18218862
64DNA replication-independent nucleosome organization (GO:0034724)3.16951678
65DNA replication-independent nucleosome assembly (GO:0006336)3.16951678
66regulation of nuclear cell cycle DNA replication (GO:0033262)3.15828589
67pyrimidine dimer repair (GO:0006290)3.15813992
68chromosome condensation (GO:0030261)3.14275340
69histone H3 acetylation (GO:0043966)3.13105169
70metanephric mesenchyme development (GO:0072075)3.08164124
71embryonic process involved in female pregnancy (GO:0060136)3.07260799
72positive regulation of cardiac muscle tissue growth (GO:0055023)3.05616609
73negative regulation of DNA-dependent DNA replication (GO:2000104)3.04967460
74mitotic nuclear envelope disassembly (GO:0007077)3.04339525
75establishment of chromosome localization (GO:0051303)3.01882170
76polyketide metabolic process (GO:0030638)3.01325060
77doxorubicin metabolic process (GO:0044598)3.01325060
78daunorubicin metabolic process (GO:0044597)3.01325060
79negative regulation of mRNA metabolic process (GO:1903312)2.99944119
80cell differentiation involved in kidney development (GO:0061005)2.99359376
81protein K11-linked ubiquitination (GO:0070979)2.99270045
82mitotic spindle checkpoint (GO:0071174)2.98361047
83histone H3-K4 trimethylation (GO:0080182)2.97512350
84mitotic chromosome condensation (GO:0007076)2.97404155
85IMP metabolic process (GO:0046040)2.96275157
86sister chromatid segregation (GO:0000819)2.95916509
87dentate gyrus development (GO:0021542)2.95477121
88alternative mRNA splicing, via spliceosome (GO:0000380)2.94171421
89regulation of timing of cell differentiation (GO:0048505)2.93138304
90DNA integration (GO:0015074)2.91902062
91regulation of DNA-dependent DNA replication (GO:0090329)2.91822439
92regulation of DNA endoreduplication (GO:0032875)2.87935087
93histone H3-K9 methylation (GO:0051567)2.87712127
94neural tube formation (GO:0001841)2.87686195
95regulation of centrosome cycle (GO:0046605)2.87468992
96negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.87389034
97negative regulation of translation, ncRNA-mediated (GO:0040033)2.87389034
98regulation of translation, ncRNA-mediated (GO:0045974)2.87389034
99peptidyl-arginine N-methylation (GO:0035246)2.87250114
100peptidyl-arginine methylation (GO:0018216)2.87250114
101spindle checkpoint (GO:0031577)2.87209654
102meiotic nuclear division (GO:0007126)2.86935163
103regulation of mRNA splicing, via spliceosome (GO:0048024)2.86655972
104DNA double-strand break processing (GO:0000729)2.85323483
105regulation of centrosome duplication (GO:0010824)2.85239293
106monoubiquitinated protein deubiquitination (GO:0035520)2.83924586
107recombinational repair (GO:0000725)2.81590272
108nuclear envelope disassembly (GO:0051081)2.79837220
109membrane disassembly (GO:0030397)2.79837220
110negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.79039163
111negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.79039163
112negative regulation of mitotic sister chromatid segregation (GO:0033048)2.79039163
113negative regulation of mitotic sister chromatid separation (GO:2000816)2.79039163
114negative regulation of sister chromatid segregation (GO:0033046)2.79039163
115regulation of development, heterochronic (GO:0040034)2.78983382
116double-strand break repair via homologous recombination (GO:0000724)2.78736132
117positive regulation of heart growth (GO:0060421)2.78147873
118centriole assembly (GO:0098534)2.77704554
119DNA ligation (GO:0006266)2.77130975
120positive regulation of protein import into nucleus, translocation (GO:0033160)2.76802870
121mitotic spindle assembly checkpoint (GO:0007094)2.76327192
122histone H3-K36 demethylation (GO:0070544)2.75058387
123mitotic spindle organization (GO:0007052)2.74880917
124lateral ventricle development (GO:0021670)2.73653319
125kidney mesenchyme development (GO:0072074)2.73246855
126energy homeostasis (GO:0097009)2.73103653
127mesenchymal cell differentiation (GO:0048762)2.72859359
128negative regulation of chromosome segregation (GO:0051985)2.72331839
129presynaptic membrane organization (GO:0097090)2.70538640
130DNA strand renaturation (GO:0000733)2.69829089
131intra-S DNA damage checkpoint (GO:0031573)2.68181715
132interkinetic nuclear migration (GO:0022027)2.67982683
133ganglion development (GO:0061548)2.66670386
134cell proliferation in forebrain (GO:0021846)2.64123652
135regulation of non-canonical Wnt signaling pathway (GO:2000050)2.61670846
136embryonic digestive tract morphogenesis (GO:0048557)2.60901545
137negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.57743835
138poly(A)+ mRNA export from nucleus (GO:0016973)2.57348138
139synapsis (GO:0007129)2.55958541
140prostate gland growth (GO:0060736)2.55729086
141regulation of helicase activity (GO:0051095)2.52568473
142positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.48367895
143positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.48367895
144positive regulation of mitotic sister chromatid separation (GO:1901970)2.48367895
145mRNA splice site selection (GO:0006376)2.46813999
146negative regulation of mast cell activation (GO:0033004)2.46066804
147meiotic chromosome segregation (GO:0045132)2.45960620
148retinal cone cell development (GO:0046549)2.41754052
149superoxide anion generation (GO:0042554)2.37300570
150limb development (GO:0060173)2.37266479
151appendage development (GO:0048736)2.37266479
152negative regulation of myoblast differentiation (GO:0045662)2.36646875
153microtubule depolymerization (GO:0007019)2.36037289
154intraciliary transport (GO:0042073)2.35420265
155histone H3-K9 modification (GO:0061647)2.33685416
156cornea development in camera-type eye (GO:0061303)2.33446421
157tRNA methylation (GO:0030488)2.31879018
158peptidyl-lysine trimethylation (GO:0018023)2.31261465
159regulation of mRNA processing (GO:0050684)2.30778145
160female gonad development (GO:0008585)2.30686894
161limb bud formation (GO:0060174)2.29867198
162lymph vessel development (GO:0001945)2.29225230
163negative regulation of dendrite morphogenesis (GO:0050774)2.28717305
164startle response (GO:0001964)2.28683482
165mesenchymal-epithelial cell signaling (GO:0060638)2.27694891
166centriole replication (GO:0007099)2.26515653
167developmental pigmentation (GO:0048066)2.25718556
168negative regulation of osteoblast proliferation (GO:0033689)2.25677604
169N-terminal protein amino acid acetylation (GO:0006474)2.25612448
170inner ear receptor cell differentiation (GO:0060113)2.25238005
171paraxial mesoderm development (GO:0048339)2.24636053
172replication fork processing (GO:0031297)2.22716630
173kidney morphogenesis (GO:0060993)2.22266465
174somite development (GO:0061053)2.19925219
175positive regulation of DNA-dependent DNA replication (GO:2000105)2.19345850
176response to X-ray (GO:0010165)2.19344207
177DNA catabolic process, exonucleolytic (GO:0000738)2.17836308
178sympathetic nervous system development (GO:0048485)2.17007248
179regulation of pigment cell differentiation (GO:0050932)2.16155177
180DNA synthesis involved in DNA repair (GO:0000731)2.14312599
181protein K6-linked ubiquitination (GO:0085020)2.13249793
182photoreceptor cell maintenance (GO:0045494)2.12811565
183negative regulation of phagocytosis (GO:0050765)2.12386649
184dendritic cell chemotaxis (GO:0002407)2.11009064
185preassembly of GPI anchor in ER membrane (GO:0016254)2.10882518

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.54179758
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse3.19309257
3TP63_19390658_ChIP-ChIP_HaCaT_Human2.77675182
4POU3F2_20337985_ChIP-ChIP_501MEL_Human2.74733292
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.66930780
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.66123089
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.64379699
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.63185969
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.62840244
10GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.60666223
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.43745625
12E2F7_22180533_ChIP-Seq_HELA_Human2.38510414
13GATA1_22025678_ChIP-Seq_K562_Human2.38378333
14PCGF2_27294783_Chip-Seq_ESCs_Mouse2.35070425
15EWS_26573619_Chip-Seq_HEK293_Human2.22328290
16CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.21299239
17POU5F1_16153702_ChIP-ChIP_HESCs_Human2.17779664
18PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.15900914
19FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.09339806
20SUZ12_27294783_Chip-Seq_NPCs_Mouse2.07081649
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.04788591
22FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.04236290
23FUS_26573619_Chip-Seq_HEK293_Human2.04182165
24EZH2_22144423_ChIP-Seq_EOC_Human2.03173275
25PCGF2_27294783_Chip-Seq_NPCs_Mouse2.01918210
26SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.99878400
27VDR_22108803_ChIP-Seq_LS180_Human1.98400737
28ELK1_19687146_ChIP-ChIP_HELA_Human1.97334800
29NFE2_27457419_Chip-Seq_LIVER_Mouse1.96239630
30IGF1R_20145208_ChIP-Seq_DFB_Human1.96009226
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.95590780
32CBX2_27304074_Chip-Seq_ESCs_Mouse1.91448954
33* P300_19829295_ChIP-Seq_ESCs_Human1.90591984
34TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.86624308
35EZH2_27294783_Chip-Seq_NPCs_Mouse1.84526193
36FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.84019916
37RNF2_27304074_Chip-Seq_NSC_Mouse1.83876242
38TAF15_26573619_Chip-Seq_HEK293_Human1.83686560
39ZNF274_21170338_ChIP-Seq_K562_Hela1.81241298
40SMAD_19615063_ChIP-ChIP_OVARY_Human1.81179047
41NANOG_18555785_Chip-Seq_ESCs_Mouse1.81172182
42FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.79664956
43E2F1_18555785_Chip-Seq_ESCs_Mouse1.77300852
44TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.76908953
45EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.75929755
46P53_22387025_ChIP-Seq_ESCs_Mouse1.72379580
47SUZ12_18555785_Chip-Seq_ESCs_Mouse1.69395197
48EGR1_19374776_ChIP-ChIP_THP-1_Human1.65136584
49RBPJ_22232070_ChIP-Seq_NCS_Mouse1.64081308
50PADI4_21655091_ChIP-ChIP_MCF-7_Human1.63666658
51STAT3_18555785_Chip-Seq_ESCs_Mouse1.62755493
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59964473
53MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.59955538
54PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.59838157
55EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.56902705
56* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.56832707
57PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56768794
58NMYC_18555785_Chip-Seq_ESCs_Mouse1.55483691
59CMYC_18555785_Chip-Seq_ESCs_Mouse1.54096528
60E2F1_21310950_ChIP-Seq_MCF-7_Human1.53608999
61P300_18555785_Chip-Seq_ESCs_Mouse1.53099748
62AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.51431565
63RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.51330419
64BCAT_22108803_ChIP-Seq_LS180_Human1.47999369
65OCT4_18555785_Chip-Seq_ESCs_Mouse1.45833903
66SMAD4_21799915_ChIP-Seq_A2780_Human1.42100972
67KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.40621913
68RUNX1_27457419_Chip-Seq_LIVER_Mouse1.40231360
69ER_23166858_ChIP-Seq_MCF-7_Human1.39415717
70RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.37274470
71SOX2_18555785_Chip-Seq_ESCs_Mouse1.37251999
72VDR_23849224_ChIP-Seq_CD4+_Human1.36119244
73EED_16625203_ChIP-ChIP_MESCs_Mouse1.35879798
74MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.35235026
75TAL1_26923725_Chip-Seq_HPCs_Mouse1.34774895
76IRF1_19129219_ChIP-ChIP_H3396_Human1.33586746
77SMAD3_21741376_ChIP-Seq_EPCs_Human1.33583932
78ZFX_18555785_Chip-Seq_ESCs_Mouse1.33285407
79CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32927475
80PU1_27457419_Chip-Seq_LIVER_Mouse1.32480007
81* TCF4_23295773_ChIP-Seq_U87_Human1.30902195
82CBP_20019798_ChIP-Seq_JUKART_Human1.29671280
83IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.29671280
84RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.29235890
85KLF4_18555785_Chip-Seq_ESCs_Mouse1.29060876
86MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28386744
87CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.28294858
88NOTCH1_21737748_ChIP-Seq_TLL_Human1.27590283
89SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.26951020
90CIITA_25753668_ChIP-Seq_RAJI_Human1.25583095
91PIAS1_25552417_ChIP-Seq_VCAP_Human1.24504660
92IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.24210644
93UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.23353483
94SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23150369
95ESRRB_18555785_Chip-Seq_ESCs_Mouse1.23015028
96STAT3_23295773_ChIP-Seq_U87_Human1.22246347
97CREB1_15753290_ChIP-ChIP_HEK293T_Human1.21223508
98TOP2B_26459242_ChIP-Seq_MCF-7_Human1.21215710
99CTBP1_25329375_ChIP-Seq_LNCAP_Human1.20998050
100CTCF_18555785_Chip-Seq_ESCs_Mouse1.20754353
101WT1_19549856_ChIP-ChIP_CCG9911_Human1.20191409
102OCT4_21477851_ChIP-Seq_ESCs_Mouse1.19411116
103CTBP2_25329375_ChIP-Seq_LNCAP_Human1.18326893
104CRX_20693478_ChIP-Seq_RETINA_Mouse1.17240875
105STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17211101
106CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.17166967
107TCF4_18268006_ChIP-ChIP_LS174T_Human1.16579422
108MYC_18940864_ChIP-ChIP_HL60_Human1.13396613
109IRF8_22096565_ChIP-ChIP_GC-B_Human1.13182562
110SMAD1_18555785_Chip-Seq_ESCs_Mouse1.13040186
111TP53_18474530_ChIP-ChIP_U2OS_Human1.12974685
112SOX2_16153702_ChIP-ChIP_HESCs_Human1.12965824
113OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12791666
114YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12635226
115* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.12501363
116NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.12363693
117E2F4_17652178_ChIP-ChIP_JURKAT_Human1.11129474
118POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10763085
119TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10763085
120ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.10760523
121AR_21909140_ChIP-Seq_LNCAP_Human1.10427128
122KLF5_20875108_ChIP-Seq_MESCs_Mouse1.10359832
123SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.09711521
124CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.09612498
125FLI1_21867929_ChIP-Seq_TH2_Mouse1.08698010
126NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08005436
127EZH2_27304074_Chip-Seq_ESCs_Mouse1.07670285
128JARID2_20064375_ChIP-Seq_MESCs_Mouse1.07650813
129NANOG_16153702_ChIP-ChIP_HESCs_Human1.07353775
130KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.07189828
131SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.06281031
132* FOXP3_21729870_ChIP-Seq_TREG_Human1.06273319
133CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.05757069
134PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.05398667
135ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.05203227
136PKCTHETA_26484144_Chip-Seq_BREAST_Human1.05123053
137CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.04492904
138SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.02823171
139AR_21572438_ChIP-Seq_LNCaP_Human1.02371025
140TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.02156547
141SOX9_26525672_Chip-Seq_HEART_Mouse1.01902147
142EST1_17652178_ChIP-ChIP_JURKAT_Human0.99752157
143FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99700075
144RUNX2_22187159_ChIP-Seq_PCA_Human0.99633145
145FOXM1_26456572_ChIP-Seq_MCF-7_Human0.98732496
146* GABP_17652178_ChIP-ChIP_JURKAT_Human0.96893064
147FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.96226979
148TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.92128493

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.11081263
2MP0002396_abnormal_hematopoietic_system3.81421023
3MP0005171_absent_coat_pigmentation3.53894165
4MP0000566_synostosis3.22806710
5MP0003941_abnormal_skin_development3.12268714
6MP0003787_abnormal_imprinting3.00042740
7MP0001188_hyperpigmentation2.97955444
8MP0008057_abnormal_DNA_replication2.73577446
9MP0005409_darkened_coat_color2.59463888
10MP0002638_abnormal_pupillary_reflex2.52989401
11MP0005647_abnormal_sex_gland2.39911506
12MP0002102_abnormal_ear_morphology2.31759326
13MP0001529_abnormal_vocalization2.21419488
14MP0003136_yellow_coat_color2.12173645
15MP0005248_abnormal_Harderian_gland2.11583748
16MP0000015_abnormal_ear_pigmentation2.10264716
17MP0009697_abnormal_copulation2.07730448
18MP0003890_abnormal_embryonic-extraembry2.05785510
19MP0003121_genomic_imprinting2.05165067
20MP0000372_irregular_coat_pigmentation1.94588412
21MP0003693_abnormal_embryo_hatching1.91777987
22MP0008058_abnormal_DNA_repair1.90804627
23MP0002938_white_spotting1.87799771
24MP0005503_abnormal_tendon_morphology1.74865816
25MP0000569_abnormal_digit_pigmentation1.72306545
26MP0002277_abnormal_respiratory_mucosa1.59297073
27MP0003567_abnormal_fetal_cardiomyocyte1.58736815
28MP0001986_abnormal_taste_sensitivity1.58182944
29MP0002095_abnormal_skin_pigmentation1.57012249
30MP0008789_abnormal_olfactory_epithelium1.53149856
31MP0005394_taste/olfaction_phenotype1.51281203
32MP0005499_abnormal_olfactory_system1.51281203
33MP0005174_abnormal_tail_pigmentation1.48859654
34MP0005645_abnormal_hypothalamus_physiol1.48019199
35MP0001984_abnormal_olfaction1.46436468
36MP0004381_abnormal_hair_follicle1.44220581
37MP0003718_maternal_effect1.43848700
38MP0008877_abnormal_DNA_methylation1.42197555
39MP0002009_preneoplasia1.37663826
40MP0005646_abnormal_pituitary_gland1.37338943
41MP0004957_abnormal_blastocyst_morpholog1.34932961
42MP0000383_abnormal_hair_follicle1.25813345
43MP0003119_abnormal_digestive_system1.25541680
44MP0005253_abnormal_eye_physiology1.24852979
45MP0002177_abnormal_outer_ear1.22708874
46MP0005408_hypopigmentation1.22474778
47MP0010094_abnormal_chromosome_stability1.22275489
48MP0000049_abnormal_middle_ear1.21874860
49MP0002249_abnormal_larynx_morphology1.21432458
50MP0003122_maternal_imprinting1.18516294
51MP0004885_abnormal_endolymph1.17985972
52MP0002234_abnormal_pharynx_morphology1.16204442
53MP0001186_pigmentation_phenotype1.14126389
54MP0001672_abnormal_embryogenesis/_devel1.13996697
55MP0005380_embryogenesis_phenotype1.13996697
56MP0000427_abnormal_hair_cycle1.13890549
57MP0002160_abnormal_reproductive_system1.13089906
58MP0004197_abnormal_fetal_growth/weight/1.12268518
59MP0005389_reproductive_system_phenotype1.11875486
60MP0000026_abnormal_inner_ear1.10215724
61MP0000631_abnormal_neuroendocrine_gland1.08859099
62MP0002084_abnormal_developmental_patter1.08666791
63MP0003111_abnormal_nucleus_morphology1.08341186
64MP0003938_abnormal_ear_development1.08309825
65MP0004185_abnormal_adipocyte_glucose1.07678272
66MP0000647_abnormal_sebaceous_gland1.06704314
67MP0003984_embryonic_growth_retardation1.06040098
68MP0009672_abnormal_birth_weight1.06017524
69MP0005367_renal/urinary_system_phenotyp1.05724078
70MP0000516_abnormal_urinary_system1.05724078
71MP0002075_abnormal_coat/hair_pigmentati1.05407858
72MP0002233_abnormal_nose_morphology1.05022730
73MP0001346_abnormal_lacrimal_gland1.04617034
74MP0008995_early_reproductive_senescence1.04312936
75MP0009379_abnormal_foot_pigmentation1.04071702
76MP0002088_abnormal_embryonic_growth/wei1.04071252
77MP0003385_abnormal_body_wall1.03921791
78MP0003937_abnormal_limbs/digits/tail_de1.03544675
79MP0001340_abnormal_eyelid_morphology1.03018550
80MP0001929_abnormal_gametogenesis1.02428269
81MP0005551_abnormal_eye_electrophysiolog1.02410491
82MP0001879_abnormal_lymphatic_vessel1.02255590
83MP0001286_abnormal_eye_development1.02097411
84MP0009703_decreased_birth_body1.01817206
85MP0008007_abnormal_cellular_replicative1.01170770
86MP0003786_premature_aging1.01004420
87MP0001145_abnormal_male_reproductive1.00902669
88MP0002822_catalepsy0.99057277
89MP0000653_abnormal_sex_gland0.98963850
90MP0004924_abnormal_behavior0.98079156
91MP0005386_behavior/neurological_phenoty0.98079156
92MP0002132_abnormal_respiratory_system0.97659074
93MP0003755_abnormal_palate_morphology0.97593490
94MP0003861_abnormal_nervous_system0.97295741
95MP0001119_abnormal_female_reproductive0.96573169
96MP0000681_abnormal_thyroid_gland0.96570051
97MP0001486_abnormal_startle_reflex0.95625824
98MP0008932_abnormal_embryonic_tissue0.95522768
99MP0003935_abnormal_craniofacial_develop0.94940874
100MP0001919_abnormal_reproductive_system0.94773501
101MP0002163_abnormal_gland_morphology0.94201768
102MP0006072_abnormal_retinal_apoptosis0.94195269
103MP0010678_abnormal_skin_adnexa0.92964800
104MP0000778_abnormal_nervous_system0.91894966
105MP0003115_abnormal_respiratory_system0.91401545
106MP0002751_abnormal_autonomic_nervous0.90225545
107MP0001697_abnormal_embryo_size0.89612254
108MP0004742_abnormal_vestibular_system0.89312592
109MP0003698_abnormal_male_reproductive0.89124822
110MP0000678_abnormal_parathyroid_gland0.88746788
111MP0010386_abnormal_urinary_bladder0.88113662
112MP0003943_abnormal_hepatobiliary_system0.87745731
113MP0002928_abnormal_bile_duct0.87472463
114MP0002085_abnormal_embryonic_tissue0.87293187
115MP0008438_abnormal_cutaneous_collagen0.86531401
116MP0001177_atelectasis0.86287970
117MP0000432_abnormal_head_morphology0.85064059
118MP0002092_abnormal_eye_morphology0.85023708
119MP0001963_abnormal_hearing_physiology0.84798048
120MP0000613_abnormal_salivary_gland0.83430536
121MP0002116_abnormal_craniofacial_bone0.82756272
122MP0003172_abnormal_lysosome_physiology0.82578832
123MP0000371_diluted_coat_color0.81804938
124MP0010030_abnormal_orbit_morphology0.81440324
125MP0003936_abnormal_reproductive_system0.80686211
126MP0001293_anophthalmia0.80617987
127MP0009250_abnormal_appendicular_skeleto0.80237514
128MP0003942_abnormal_urinary_system0.80213182
129MP0005391_vision/eye_phenotype0.79937406
130MP0001502_abnormal_circadian_rhythm0.79362498
131MP0002109_abnormal_limb_morphology0.77028433
132MP0001849_ear_inflammation0.76890147
133MP0002184_abnormal_innervation0.75861873
134MP0001851_eye_inflammation0.75298909
135MP0002653_abnormal_ependyma_morphology0.74907070
136MP0003221_abnormal_cardiomyocyte_apopto0.73489462
137MP0001727_abnormal_embryo_implantation0.73479236
138MP0010307_abnormal_tumor_latency0.73439849
139MP0005075_abnormal_melanosome_morpholog0.73203427
140MP0001835_abnormal_antigen_presentation0.71882426
141MP0000350_abnormal_cell_proliferation0.71183839
142MP0002111_abnormal_tail_morphology0.71139550
143MP0002697_abnormal_eye_size0.70492605
144MP0002876_abnormal_thyroid_physiology0.70350937
145MP0004134_abnormal_chest_morphology0.70157449
146MP0005379_endocrine/exocrine_gland_phen0.70157309
147MP0001730_embryonic_growth_arrest0.69107055
148MP0005671_abnormal_response_to0.69040315
149MP0004883_abnormal_blood_vessel0.67913659
150MP0002006_tumorigenesis0.67429523
151MP0005395_other_phenotype0.66988846
152MP0000538_abnormal_urinary_bladder0.66345485
153MP0001485_abnormal_pinna_reflex0.66288996
154MP0003077_abnormal_cell_cycle0.65840401
155MP0002210_abnormal_sex_determination0.65669373

Predicted human phenotypes

RankGene SetZ-score
1Hypoplasia of the thymus (HP:0000778)5.90761519
2Acute lymphatic leukemia (HP:0006721)4.98339873
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.54389436
4Chromsome breakage (HP:0040012)4.02308584
5Abnormality of the nasal septum (HP:0000419)3.87249685
6Abnormal hair whorl (HP:0010721)3.82210879
7Abnormality of incisor morphology (HP:0011063)3.80214023
8Hip dysplasia (HP:0001385)3.79373843
9Abnormality of the fingertips (HP:0001211)3.59821679
10Severe visual impairment (HP:0001141)3.39355043
11Abnormality of the renal cortex (HP:0011035)3.39210165
12Turricephaly (HP:0000262)3.24985174
13Neoplasm of the adrenal cortex (HP:0100641)3.14216340
14Poor suck (HP:0002033)3.12256673
15Shoulder girdle muscle weakness (HP:0003547)3.07998376
16True hermaphroditism (HP:0010459)2.93932113
17Duplicated collecting system (HP:0000081)2.91770974
18Abnormality of the prostate (HP:0008775)2.87502854
19Abnormality of the renal collecting system (HP:0004742)2.86553701
20Hypothermia (HP:0002045)2.81947095
21Thyroid carcinoma (HP:0002890)2.79330126
22Curly hair (HP:0002212)2.79274862
23Hypochromic microcytic anemia (HP:0004840)2.66452494
24Ectopic kidney (HP:0000086)2.66038611
25Papillary thyroid carcinoma (HP:0002895)2.64879605
26Abnormality of the columella (HP:0009929)2.62144483
27Acute myeloid leukemia (HP:0004808)2.60934089
28Limb hypertonia (HP:0002509)2.52235778
29Abnormality of the incisor (HP:0000676)2.50898138
30Medulloblastoma (HP:0002885)2.46552055
31Abnormality of macular pigmentation (HP:0008002)2.44663380
32Febrile seizures (HP:0002373)2.42880390
33Abnormality of the musculature of the pelvis (HP:0001469)2.41095257
34Abnormality of the hip-girdle musculature (HP:0001445)2.41095257
35Cubitus valgus (HP:0002967)2.38815074
36Clitoromegaly (HP:0000057)2.38304863
37Abnormality of the nasolacrimal system (HP:0000614)2.37147034
38Small intestinal stenosis (HP:0012848)2.36004541
39Duodenal stenosis (HP:0100867)2.36004541
40Intellectual disability, moderate (HP:0002342)2.35503275
41Abnormality of the parietal bone (HP:0002696)2.33855173
42Nephroblastoma (Wilms tumor) (HP:0002667)2.32837822
43Abnormal biliary tract morphology (HP:0012440)2.32771703
44Exotropia (HP:0000577)2.32736465
45Abnormality of DNA repair (HP:0003254)2.30697598
46Nasolacrimal duct obstruction (HP:0000579)2.29308657
47Myelodysplasia (HP:0002863)2.29218494
48Protruding tongue (HP:0010808)2.27793839
49Pelvic girdle muscle weakness (HP:0003749)2.25904886
50Thin upper lip vermilion (HP:0000219)2.25723080
51Abnormality of the lacrimal duct (HP:0011481)2.24768654
52Clubbing of toes (HP:0100760)2.23655166
53Embryonal renal neoplasm (HP:0011794)2.22914736
54Osteomalacia (HP:0002749)2.21058273
55Impulsivity (HP:0100710)2.20666977
56Septo-optic dysplasia (HP:0100842)2.20057652
57Dyskinesia (HP:0100660)2.17928590
58Albinism (HP:0001022)2.17344857
59Abnormality of the duodenum (HP:0002246)2.16241692
60Aplasia cutis congenita (HP:0001057)2.13694809
61Abnormality of the labia minora (HP:0012880)2.13567067
62Lip pit (HP:0100267)2.13476981
63Pancreatic islet-cell hyperplasia (HP:0004510)2.11528672
64Hypoplastic left heart (HP:0004383)2.11423970
65Pancreatic fibrosis (HP:0100732)2.11331731
66Drooling (HP:0002307)2.09757619
67Meckel diverticulum (HP:0002245)2.07379876
68White forelock (HP:0002211)2.07255061
69Abnormality of the phalanges of the hallux (HP:0010057)2.06510134
70Fair hair (HP:0002286)2.00801730
71Absent eyebrow (HP:0002223)2.00369766
72Abnormal cartilage morphology (HP:0002763)2.00301842
73B lymphocytopenia (HP:0010976)2.00043456
74Abnormality of chromosome stability (HP:0003220)1.99945184
75Asymmetry of the thorax (HP:0001555)1.98784016
76Brushfield spots (HP:0001088)1.98120184
77Thyroiditis (HP:0100646)1.98049080
78Congenital stationary night blindness (HP:0007642)1.97933219
79Patchy hypopigmentation of hair (HP:0011365)1.97893526
80Pancreatic cysts (HP:0001737)1.97695089
81Shawl scrotum (HP:0000049)1.97315308
82Abnormal number of incisors (HP:0011064)1.96523239
83Hyperglycinemia (HP:0002154)1.96481926
84Hypoplastic heart (HP:0001961)1.96248493
85Long foot (HP:0001833)1.96228326
86Abnormality of the ileum (HP:0001549)1.96071693
87Intestinal atresia (HP:0011100)1.96059783
88Aplasia/Hypoplasia of the uvula (HP:0010293)1.95489260
89Generalized hypopigmentation of hair (HP:0011358)1.95074078
90Hepatoblastoma (HP:0002884)1.94699126
91Alveolar cell carcinoma (HP:0006519)1.93792980
92Excessive salivation (HP:0003781)1.93692878
93Depressed nasal tip (HP:0000437)1.92758635
94Preaxial hand polydactyly (HP:0001177)1.92749923
95Palpebral edema (HP:0100540)1.92451946
96Increased number of teeth (HP:0011069)1.91867758
97Abnormality of the pancreatic islet cells (HP:0006476)1.91769053
98Abnormality of endocrine pancreas physiology (HP:0012093)1.91769053
99Abnormality of the right ventricle (HP:0001707)1.90365401
100Medial flaring of the eyebrow (HP:0010747)1.90063927
101Stomach cancer (HP:0012126)1.88057071
102Renal cortical cysts (HP:0000803)1.85421659
103Prostate neoplasm (HP:0100787)1.85151043
104Aplasia/Hypoplasia of the tibia (HP:0005772)1.84113043
105Smooth philtrum (HP:0000319)1.83577359
106Thyroid-stimulating hormone excess (HP:0002925)1.83422952
107Poor coordination (HP:0002370)1.83317444
108Increased nuchal translucency (HP:0010880)1.82013414
109Nephronophthisis (HP:0000090)1.81820233
110Short middle phalanx of the 5th finger (HP:0004220)1.79872592
111Submucous cleft hard palate (HP:0000176)1.78902362
112Decreased central vision (HP:0007663)1.77753074
113Duplication of thumb phalanx (HP:0009942)1.77449694
114Pendular nystagmus (HP:0012043)1.77347730
115Abnormality of secondary sexual hair (HP:0009888)1.77042056
116Abnormality of the axillary hair (HP:0100134)1.77042056
117Tented upper lip vermilion (HP:0010804)1.76330161
118Cupped ear (HP:0000378)1.75664372
119Sloping forehead (HP:0000340)1.75586314
120Abnormality of the preputium (HP:0100587)1.74524178
121Abnormality of the clitoris (HP:0000056)1.74439525
122Abnormality of B cell number (HP:0010975)1.74160306
123Alacrima (HP:0000522)1.72917769
124Prominent nose (HP:0000448)1.72884264
125Renal dysplasia (HP:0000110)1.72782797
126Metatarsus adductus (HP:0001840)1.70639254
127Abnormality of the carotid arteries (HP:0005344)1.70392360
128Cystic hygroma (HP:0000476)1.70157716
129Abnormal social behavior (HP:0012433)1.69579071
130Impaired social interactions (HP:0000735)1.69579071
131Morphological abnormality of the middle ear (HP:0008609)1.69273389
132Male pseudohermaphroditism (HP:0000037)1.68432145
133Colon cancer (HP:0003003)1.68325817
134Hypoplasia of the fovea (HP:0007750)1.68202797
135Aplasia/Hypoplasia of the fovea (HP:0008060)1.68202797
136Decreased lacrimation (HP:0000633)1.67979050
137Inappropriate behavior (HP:0000719)1.67791976
138Neoplasm of the tracheobronchial system (HP:0100552)1.66904241
139Chronic diarrhea (HP:0002028)1.66223628
140Nephrogenic diabetes insipidus (HP:0009806)1.66149981
141Self-mutilation (HP:0000742)1.65566730
142Abnormality of the renal medulla (HP:0100957)1.64875650
143Optic nerve hypoplasia (HP:0000609)1.64107672
144Narrow forehead (HP:0000341)1.63790619
145Abnormal respiratory motile cilium morphology (HP:0005938)1.63659052
146Abnormal respiratory epithelium morphology (HP:0012253)1.63659052
147Long eyelashes (HP:0000527)1.63397811
148Chorioretinal coloboma (HP:0000567)1.63359690
149Abnormality of male internal genitalia (HP:0000022)1.62728755
150Macroorchidism (HP:0000053)1.61920314
151Short tibia (HP:0005736)1.61853151
152Abnormal lung lobation (HP:0002101)1.61615966
153Heterotopia (HP:0002282)1.61600922
154Overlapping toe (HP:0001845)1.61452916
155Hypoplasia of the maxilla (HP:0000327)1.61316323
156Poor eye contact (HP:0000817)1.61311108
157Mesomelia (HP:0003027)1.60968437
158Hematochezia (HP:0002573)1.60578056
159Death in childhood (HP:0003819)1.60322682
160Volvulus (HP:0002580)1.60270422
161Microvesicular hepatic steatosis (HP:0001414)1.60158272
162Bifid tongue (HP:0010297)1.59848592
163Postaxial foot polydactyly (HP:0001830)1.58944319
164Occipital encephalocele (HP:0002085)1.58812021
165Deep philtrum (HP:0002002)1.58466824
166Hypoplastic iliac wings (HP:0002866)1.57588045
167Capillary hemangiomas (HP:0005306)1.56690944
168Pulmonary artery stenosis (HP:0004415)1.56225753
169Chronic hepatic failure (HP:0100626)1.55778717
170Median cleft lip (HP:0000161)1.54420727
171Embryonal neoplasm (HP:0002898)1.54037548
172Scrotal hypoplasia (HP:0000046)1.53822153
173Cystic liver disease (HP:0006706)1.53764560

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE16.28483447
2ZAK4.81223880
3BRSK23.61492761
4FRK3.56353931
5PNCK2.96452192
6CASK2.88512569
7MKNK22.79134463
8AKT32.70588023
9WNK32.68838915
10TNIK2.51268871
11ERBB32.31960630
12SRPK12.24286129
13NEK12.23545425
14MKNK12.18891694
15TAF12.15135848
16SGK22.03187126
17TXK1.98254448
18ACVR1B1.91336831
19STK161.89586818
20YES11.87132889
21MAP3K141.86000207
22FGFR21.82537469
23SIK31.80564082
24KSR11.73370874
25BMPR1B1.67141252
26FGFR31.65601656
27MAP3K41.63322527
28EIF2AK21.60750492
29EIF2AK31.58278718
30NEK61.53034242
31BRSK11.48960836
32INSRR1.47841058
33NUAK11.47237148
34VRK11.46229204
35CDK31.45037988
36BRD41.41811341
37PRPF4B1.40472823
38ADRBK21.39273925
39MAP2K71.35360406
40MAPK131.35201062
41ERBB21.31413484
42IRAK31.24906946
43PLK31.21049459
44SGK2231.15782908
45SGK4941.15782908
46SGK31.13205235
47PLK41.12773769
48CHUK1.06979156
49CSNK1G21.06330769
50NEK91.05793280
51IRAK41.04800540
52BMPR21.04759221
53MATK1.03519155
54TRPM71.02876085
55MARK31.02182179
56SIK21.01168398
57TRIM280.99975416
58CAMKK20.98255362
59ATR0.98135615
60CSNK1G30.97144300
61TEC0.94988216
62LATS10.94864150
63CLK10.94590981
64STK38L0.90326178
65CDK80.88252653
66GRK10.87849397
67TLK10.82008696
68NEK20.81302559
69BUB10.79055266
70TGFBR10.79045219
71PKN10.78750786
72IKBKE0.78489411
73IKBKB0.77900847
74PIK3CA0.76458648
75STK40.75887729
76CDC70.75709982
77CDK70.73420115
78TTK0.71474664
79CAMK40.71127480
80RAF10.70312589
81DYRK1A0.67712472
82JAK30.65292198
83EPHA30.63985940
84UHMK10.61688941
85ATM0.61285876
86CDK60.58568607
87MAPK100.57754157
88CHEK20.57163097
89CDK120.56414353
90FGFR10.55935609
91DYRK20.55918666
92NTRK20.55606536
93PASK0.54774011
94NLK0.53898858
95STK30.52082644
96AKT10.51936303
97PLK20.51437259
98SGK10.51123475
99DYRK30.50473685
100RPS6KB10.48669561
101CSNK1A1L0.47314867
102GRK70.47292456
103EIF2AK10.46942925
104PRKCE0.44654958
105DMPK0.44341880
106TSSK60.44166790
107MAPK70.44164257
108CDK10.43919162
109CHEK10.42956025
110LYN0.42846820
111AURKB0.42557262
112ERBB40.42528038
113RPS6KA50.42339992
114PRKDC0.42329915
115PLK10.41689882
116PINK10.40672737
117CSNK1E0.40130827
118PIM10.40110362
119MAPKAPK30.39164942
120RPS6KA40.38277222
121BCR0.37609769
122GSK3B0.36379194
123PAK30.36213422
124MAPK140.36115742
125CDK20.35928588
126TNK20.34818550
127EGFR0.32407291
128BTK0.32296714
129PBK0.31888859
130ROCK10.31029337
131CAMK1G0.29928295
132CSNK1G10.27430494
133PTK2B0.26710728
134STK240.26452764
135PRKG10.26306018
136BLK0.25452290
137CSNK1D0.24767185
138IRAK10.23647224
139WNK10.23417601
140MAP3K80.22013817

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034602.84801331
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.72618909
3Oocyte meiosis_Homo sapiens_hsa041142.37922690
4Base excision repair_Homo sapiens_hsa034102.19779446
5Progesterone-mediated oocyte maturation_Homo sapiens_hsa049142.15204303
6ABC transporters_Homo sapiens_hsa020102.14104392
7Homologous recombination_Homo sapiens_hsa034402.05504599
8Phototransduction_Homo sapiens_hsa047442.03237217
9Non-homologous end-joining_Homo sapiens_hsa034501.97194353
10Basal transcription factors_Homo sapiens_hsa030221.87986622
11Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.79738940
12NF-kappa B signaling pathway_Homo sapiens_hsa040641.79281327
13Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.75491594
14RNA degradation_Homo sapiens_hsa030181.72798689
15Nitrogen metabolism_Homo sapiens_hsa009101.69725521
16Autoimmune thyroid disease_Homo sapiens_hsa053201.64452884
17Spliceosome_Homo sapiens_hsa030401.62271700
18Allograft rejection_Homo sapiens_hsa053301.60714327
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.58991985
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.55487999
21Systemic lupus erythematosus_Homo sapiens_hsa053221.55068635
22Butanoate metabolism_Homo sapiens_hsa006501.51547223
23Mismatch repair_Homo sapiens_hsa034301.47098382
24Herpes simplex infection_Homo sapiens_hsa051681.44984168
25Pancreatic cancer_Homo sapiens_hsa052121.43207468
26Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.41232871
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.40278411
28Transcriptional misregulation in cancer_Homo sapiens_hsa052021.39468630
29Primary immunodeficiency_Homo sapiens_hsa053401.38947389
30Nicotine addiction_Homo sapiens_hsa050331.36539998
31Nucleotide excision repair_Homo sapiens_hsa034201.35442478
32Notch signaling pathway_Homo sapiens_hsa043301.35054936
33Cell cycle_Homo sapiens_hsa041101.32770790
34Non-small cell lung cancer_Homo sapiens_hsa052231.27879339
35mRNA surveillance pathway_Homo sapiens_hsa030151.22511172
36Arachidonic acid metabolism_Homo sapiens_hsa005901.22262210
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.21031762
38TGF-beta signaling pathway_Homo sapiens_hsa043501.18239947
39RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.16985362
40Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.16015747
41Prostate cancer_Homo sapiens_hsa052151.14228620
42RNA polymerase_Homo sapiens_hsa030201.12533598
43DNA replication_Homo sapiens_hsa030301.12525251
44Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.12322660
45One carbon pool by folate_Homo sapiens_hsa006701.10700606
46Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.10295458
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.10276947
48Propanoate metabolism_Homo sapiens_hsa006401.08931363
49Measles_Homo sapiens_hsa051621.08374812
50Protein export_Homo sapiens_hsa030601.06598837
51p53 signaling pathway_Homo sapiens_hsa041151.06266792
52Hematopoietic cell lineage_Homo sapiens_hsa046401.05670145
53Asthma_Homo sapiens_hsa053101.04011066
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.02407639
55Melanoma_Homo sapiens_hsa052181.02082443
56Graft-versus-host disease_Homo sapiens_hsa053321.02079895
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.99668377
58Alcoholism_Homo sapiens_hsa050340.98770035
59Basal cell carcinoma_Homo sapiens_hsa052170.98210977
60Colorectal cancer_Homo sapiens_hsa052100.97725146
61Taste transduction_Homo sapiens_hsa047420.95874185
62Thyroid cancer_Homo sapiens_hsa052160.95395634
63MicroRNAs in cancer_Homo sapiens_hsa052060.94621329
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.92723621
65Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.92478529
66Wnt signaling pathway_Homo sapiens_hsa043100.89196814
67Glioma_Homo sapiens_hsa052140.88887235
68Maturity onset diabetes of the young_Homo sapiens_hsa049500.87220178
69Chronic myeloid leukemia_Homo sapiens_hsa052200.86478426
70Regulation of autophagy_Homo sapiens_hsa041400.84684590
71Selenocompound metabolism_Homo sapiens_hsa004500.82536635
72Gap junction_Homo sapiens_hsa045400.82137289
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.81718490
74Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.81151996
75Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.80547857
76Morphine addiction_Homo sapiens_hsa050320.80246577
77Jak-STAT signaling pathway_Homo sapiens_hsa046300.80208106
78Serotonergic synapse_Homo sapiens_hsa047260.79496475
79Hepatitis B_Homo sapiens_hsa051610.78847373
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.77623836
81Purine metabolism_Homo sapiens_hsa002300.77318301
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.76597213
83HTLV-I infection_Homo sapiens_hsa051660.74894642
84Type I diabetes mellitus_Homo sapiens_hsa049400.74447678
85Peroxisome_Homo sapiens_hsa041460.72498443
86Sphingolipid metabolism_Homo sapiens_hsa006000.71321160
87Influenza A_Homo sapiens_hsa051640.71298155
88Long-term depression_Homo sapiens_hsa047300.71081192
89Ether lipid metabolism_Homo sapiens_hsa005650.69747223
90Hippo signaling pathway_Homo sapiens_hsa043900.69667889
91Adherens junction_Homo sapiens_hsa045200.67646879
92Ovarian steroidogenesis_Homo sapiens_hsa049130.67256889
93Pyrimidine metabolism_Homo sapiens_hsa002400.66975601
94Toll-like receptor signaling pathway_Homo sapiens_hsa046200.65473155
95NOD-like receptor signaling pathway_Homo sapiens_hsa046210.64819606
96Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.64045281
97Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63045153
98Circadian rhythm_Homo sapiens_hsa047100.62978310
99Steroid biosynthesis_Homo sapiens_hsa001000.62110214
100FoxO signaling pathway_Homo sapiens_hsa040680.61264509
101Viral carcinogenesis_Homo sapiens_hsa052030.60688297
102SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60478848
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.60441943
104Pathways in cancer_Homo sapiens_hsa052000.59504555
105Hedgehog signaling pathway_Homo sapiens_hsa043400.59372986
106Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57630369
107Inositol phosphate metabolism_Homo sapiens_hsa005620.57470682
108RNA transport_Homo sapiens_hsa030130.57422917
109Axon guidance_Homo sapiens_hsa043600.56969616
110Dorso-ventral axis formation_Homo sapiens_hsa043200.56498093
111Rheumatoid arthritis_Homo sapiens_hsa053230.56345966
112Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55704207
113Fatty acid biosynthesis_Homo sapiens_hsa000610.54786003
114Epstein-Barr virus infection_Homo sapiens_hsa051690.53804465
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.53147339
116N-Glycan biosynthesis_Homo sapiens_hsa005100.52155072
117mTOR signaling pathway_Homo sapiens_hsa041500.51041453
118TNF signaling pathway_Homo sapiens_hsa046680.50573474
119Small cell lung cancer_Homo sapiens_hsa052220.50457510
120Choline metabolism in cancer_Homo sapiens_hsa052310.50369142
121Acute myeloid leukemia_Homo sapiens_hsa052210.49952883
122Malaria_Homo sapiens_hsa051440.49070153
123Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49011807
124Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.48903235
125Endometrial cancer_Homo sapiens_hsa052130.48827805
126Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48811621
127Long-term potentiation_Homo sapiens_hsa047200.48334407
128Lysine degradation_Homo sapiens_hsa003100.48056897
129ErbB signaling pathway_Homo sapiens_hsa040120.47941936
130Sphingolipid signaling pathway_Homo sapiens_hsa040710.47193276
131Chemokine signaling pathway_Homo sapiens_hsa040620.42523839
132Prolactin signaling pathway_Homo sapiens_hsa049170.42466359
133Thyroid hormone signaling pathway_Homo sapiens_hsa049190.42448521
134PI3K-Akt signaling pathway_Homo sapiens_hsa041510.42379357
135Shigellosis_Homo sapiens_hsa051310.40475741
136Renal cell carcinoma_Homo sapiens_hsa052110.39527357
137Ras signaling pathway_Homo sapiens_hsa040140.38427888
138Oxytocin signaling pathway_Homo sapiens_hsa049210.37686865
139Vitamin digestion and absorption_Homo sapiens_hsa049770.36931997
140Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35811839
141Dopaminergic synapse_Homo sapiens_hsa047280.35442518
142T cell receptor signaling pathway_Homo sapiens_hsa046600.34704719
143Olfactory transduction_Homo sapiens_hsa047400.34370882
144Vascular smooth muscle contraction_Homo sapiens_hsa042700.34243130
145Fatty acid metabolism_Homo sapiens_hsa012120.33458762
146Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.31906200
147Neurotrophin signaling pathway_Homo sapiens_hsa047220.30005055
148Amphetamine addiction_Homo sapiens_hsa050310.27427808

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