ZBTB37

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of translation involved in gene silencing by miRNA (GO:0035278)5.28420421
2negative regulation of translation, ncRNA-mediated (GO:0040033)5.28420421
3regulation of translation, ncRNA-mediated (GO:0045974)5.28420421
4histone H3-K4 trimethylation (GO:0080182)4.58621577
5establishment of protein localization to Golgi (GO:0072600)4.27281561
6monoubiquitinated protein deubiquitination (GO:0035520)4.25305509
7histone H3-K36 demethylation (GO:0070544)4.01133897
8protein K11-linked deubiquitination (GO:0035871)3.77225691
9protein targeting to Golgi (GO:0000042)3.75771869
10cytoplasmic mRNA processing body assembly (GO:0033962)3.68121923
11retrograde transport, vesicle recycling within Golgi (GO:0000301)3.60223260
12cellular response to ethanol (GO:0071361)3.59404642
13histone H3-K4 methylation (GO:0051568)3.49748276
14positive regulation of developmental pigmentation (GO:0048087)3.38976619
15peptidyl-lysine trimethylation (GO:0018023)3.34733289
16activated T cell proliferation (GO:0050798)3.26430709
17regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)3.25546657
18positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)3.25546657
19interkinetic nuclear migration (GO:0022027)3.18843621
20protein K48-linked deubiquitination (GO:0071108)3.16789394
21regulation of pigment cell differentiation (GO:0050932)3.15852915
22regulation of B cell receptor signaling pathway (GO:0050855)3.12914817
23retinal cone cell development (GO:0046549)3.10398628
24establishment of nucleus localization (GO:0040023)3.06438368
25lipid translocation (GO:0034204)3.03526240
26phospholipid translocation (GO:0045332)3.03526240
27Golgi to endosome transport (GO:0006895)3.00072092
28regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.99407421
29positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.99407421
30histone lysine demethylation (GO:0070076)2.93446019
31nerve growth factor signaling pathway (GO:0038180)2.84727643
32cilium or flagellum-dependent cell motility (GO:0001539)2.82603522
33regulation of gamma-delta T cell differentiation (GO:0045586)2.81792790
34histone H3-K9 methylation (GO:0051567)2.80527883
35protein K63-linked deubiquitination (GO:0070536)2.78814035
36histone lysine methylation (GO:0034968)2.78106915
37histone demethylation (GO:0016577)2.76088977
38positive regulation of granulocyte differentiation (GO:0030854)2.75076177
39histone mRNA catabolic process (GO:0071044)2.74099511
40protein localization to Golgi apparatus (GO:0034067)2.73781863
41regulation of establishment of cell polarity (GO:2000114)2.73631112
42positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.73437728
43mitotic sister chromatid cohesion (GO:0007064)2.71403634
44regulation of gene silencing by RNA (GO:0060966)2.70592301
45regulation of posttranscriptional gene silencing (GO:0060147)2.70592301
46regulation of gene silencing by miRNA (GO:0060964)2.70592301
47cellular extravasation (GO:0045123)2.64564376
48protein targeting to vacuole (GO:0006623)2.64041780
49protein targeting to lysosome (GO:0006622)2.64041780
50establishment of protein localization to vacuole (GO:0072666)2.64041780
51regulation of gamma-delta T cell activation (GO:0046643)2.64031158
52pre-miRNA processing (GO:0031054)2.63382433
53negative regulation of cell killing (GO:0031342)2.62946765
54negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.62946765
55phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.59113063
56microglial cell activation (GO:0001774)2.58927630
57prenylation (GO:0097354)2.58277332
58protein prenylation (GO:0018342)2.58277332
59behavioral response to nicotine (GO:0035095)2.58142001
60regulation of histone H3-K27 methylation (GO:0061085)2.57231090
61central nervous system projection neuron axonogenesis (GO:0021952)2.57188362
62negative regulation of cAMP-mediated signaling (GO:0043951)2.54733243
63histone H3-K9 modification (GO:0061647)2.54336830
64negative regulation of neurotransmitter transport (GO:0051589)2.54316094
65pyrimidine nucleobase catabolic process (GO:0006208)2.52553523
66protein dealkylation (GO:0008214)2.52081847
67protein demethylation (GO:0006482)2.52081847
68epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.51253208
69histone H3-K9 demethylation (GO:0033169)2.50924678
70B cell receptor signaling pathway (GO:0050853)2.47996326
71intra-Golgi vesicle-mediated transport (GO:0006891)2.47649936
72cerebellar Purkinje cell differentiation (GO:0021702)2.44150612
73snRNA transcription (GO:0009301)2.43683937
74regulation of DNA endoreduplication (GO:0032875)2.40612040
75stress granule assembly (GO:0034063)2.36887761
76macroautophagy (GO:0016236)2.36730480
77cerebral cortex radially oriented cell migration (GO:0021799)2.36455518
78hepatocyte apoptotic process (GO:0097284)2.36180683
79microtubule anchoring (GO:0034453)2.36124454
80histone-serine phosphorylation (GO:0035404)2.35206686
81positive regulation of gamma-delta T cell activation (GO:0046645)2.34054826
82regulation of beta-amyloid formation (GO:1902003)2.32959964
83positive T cell selection (GO:0043368)2.32674610
84B cell homeostasis (GO:0001782)2.32580269
85photoreceptor cell maintenance (GO:0045494)2.32283855
86negative regulation of B cell mediated immunity (GO:0002713)2.32034677
87negative regulation of immunoglobulin mediated immune response (GO:0002890)2.32034677
88nucleus localization (GO:0051647)2.31027566
89positive regulation of mRNA catabolic process (GO:0061014)2.30900674
90spinal cord motor neuron differentiation (GO:0021522)2.30331756
91regulation of non-canonical Wnt signaling pathway (GO:2000050)2.30298902
92negative regulation of cytosolic calcium ion concentration (GO:0051481)2.29744422
93fucose catabolic process (GO:0019317)2.29060052
94L-fucose metabolic process (GO:0042354)2.29060052
95L-fucose catabolic process (GO:0042355)2.29060052
96regulation of establishment or maintenance of cell polarity (GO:0032878)2.28819126
97growth hormone receptor signaling pathway (GO:0060396)2.28818005
98detection of light stimulus involved in visual perception (GO:0050908)2.28732889
99detection of light stimulus involved in sensory perception (GO:0050962)2.28732889
100eye photoreceptor cell development (GO:0042462)2.26263545
101lateral sprouting from an epithelium (GO:0060601)2.25950638
102positive regulation of mRNA processing (GO:0050685)2.25528997
103peptidyl-lysine methylation (GO:0018022)2.25174490
104atrial cardiac muscle cell action potential (GO:0086014)2.25043911
105embryonic retina morphogenesis in camera-type eye (GO:0060059)2.24379337
106regulation of germinal center formation (GO:0002634)2.24083837
107myeloid leukocyte mediated immunity (GO:0002444)2.23531780
108pericardium development (GO:0060039)2.23382655
109rRNA catabolic process (GO:0016075)2.23260753
110replicative senescence (GO:0090399)2.22776322
111cyclic nucleotide catabolic process (GO:0009214)2.21825513
112regulation of mRNA 3-end processing (GO:0031440)2.21386294
113antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.20404966
114photoreceptor cell development (GO:0042461)2.19795143
115embryonic hemopoiesis (GO:0035162)2.19750665
116positive regulation of mRNA 3-end processing (GO:0031442)2.18987248
117mRNA splice site selection (GO:0006376)2.18789674
118cell proliferation in forebrain (GO:0021846)2.18753798
119detection of molecule of bacterial origin (GO:0032490)2.18687842
120histone methylation (GO:0016571)2.16769669
121regulation of mRNA catabolic process (GO:0061013)2.15726886
122cellular response to interleukin-15 (GO:0071350)2.15354044
123negative T cell selection (GO:0043383)2.13011563
124regulation of protein polyubiquitination (GO:1902914)2.12610534
125presynaptic membrane assembly (GO:0097105)2.12322981
126photoreceptor cell differentiation (GO:0046530)2.11573228
127eye photoreceptor cell differentiation (GO:0001754)2.11573228
128negative regulation of histone methylation (GO:0031061)2.11113612
129head development (GO:0060322)2.10927662
130retinal rod cell development (GO:0046548)2.09498934
131G-protein coupled receptor internalization (GO:0002031)2.09232197
132female gonad development (GO:0008585)2.08574164
133central nervous system neuron axonogenesis (GO:0021955)2.08319630
134dentate gyrus development (GO:0021542)2.07000129
135startle response (GO:0001964)2.06970326
136cAMP catabolic process (GO:0006198)2.05917102
137regulation of rhodopsin mediated signaling pathway (GO:0022400)2.05365399
138negative regulation of DNA-dependent DNA replication (GO:2000104)2.05048895
139mesenchymal cell differentiation (GO:0048762)2.04827690
140limb bud formation (GO:0060174)2.04524028
141presynaptic membrane organization (GO:0097090)2.04230046
142rhodopsin mediated signaling pathway (GO:0016056)2.04118375
143microtubule depolymerization (GO:0007019)2.04083003
144response to X-ray (GO:0010165)2.02943567
145response to pheromone (GO:0019236)2.02358268
146appendage development (GO:0048736)2.02262255
147limb development (GO:0060173)2.02262255
148nuclear pore complex assembly (GO:0051292)2.02142293
149retina layer formation (GO:0010842)2.01263093
150cell differentiation involved in kidney development (GO:0061005)2.01193964
151sister chromatid cohesion (GO:0007062)1.99744614
152kidney morphogenesis (GO:0060993)1.98577033
153negative thymic T cell selection (GO:0045060)1.96957022
154righting reflex (GO:0060013)1.96768177
155interferon-gamma production (GO:0032609)1.96645058
156insulin-like growth factor receptor signaling pathway (GO:0048009)1.96419320
157regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 1.95751215
158negative regulation of mast cell activation (GO:0033004)1.94518429
159regulation of inhibitory postsynaptic membrane potential (GO:0060080)1.94439284
160dendrite morphogenesis (GO:0048813)1.93455491
161regulation of histone methylation (GO:0031060)1.93151001
162neural tube formation (GO:0001841)1.92709548
163negative regulation of osteoblast proliferation (GO:0033689)1.92251986
164olfactory bulb development (GO:0021772)1.91591116

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.32714216
2SALL1_21062744_ChIP-ChIP_HESCs_Human2.76303641
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.74085263
4BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.66245839
5ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.48716947
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.48047714
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.41622529
8SMAD_19615063_ChIP-ChIP_OVARY_Human2.37987162
9SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.31976704
10ZNF274_21170338_ChIP-Seq_K562_Hela2.08357547
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.04204342
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.02179468
13POU3F2_20337985_ChIP-ChIP_501MEL_Human1.96812194
14PCGF2_27294783_Chip-Seq_ESCs_Mouse1.96447153
15EZH2_22144423_ChIP-Seq_EOC_Human1.94951543
16SUZ12_27294783_Chip-Seq_NPCs_Mouse1.93760446
17AR_21572438_ChIP-Seq_LNCaP_Human1.91871481
18PCGF2_27294783_Chip-Seq_NPCs_Mouse1.91315717
19FLI1_27457419_Chip-Seq_LIVER_Mouse1.87119039
20VDR_22108803_ChIP-Seq_LS180_Human1.83549101
21HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.79941032
22* NFE2_27457419_Chip-Seq_LIVER_Mouse1.78404793
23PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.77503077
24* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.76398158
25AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.73397402
26POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.72696269
27TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.72696269
28* NANOG_18555785_Chip-Seq_ESCs_Mouse1.67335778
29GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.65075724
30GATA1_22025678_ChIP-Seq_K562_Human1.64789977
31SMAD4_21799915_ChIP-Seq_A2780_Human1.60985559
32VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.58000258
33STAT3_23295773_ChIP-Seq_U87_Human1.57869734
34* E2F1_18555785_Chip-Seq_ESCs_Mouse1.56944319
35P300_19829295_ChIP-Seq_ESCs_Human1.56036719
36IGF1R_20145208_ChIP-Seq_DFB_Human1.55691938
37* EZH2_27294783_Chip-Seq_NPCs_Mouse1.55005473
38UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.53659301
39* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.53073263
40IRF8_22096565_ChIP-ChIP_GC-B_Human1.52369236
41TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.49911675
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.47677020
43STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.46612588
44DROSHA_22980978_ChIP-Seq_HELA_Human1.46511627
45TAF15_26573619_Chip-Seq_HEK293_Human1.44242812
46* CBP_20019798_ChIP-Seq_JUKART_Human1.43796137
47* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.43796137
48TP53_16413492_ChIP-PET_HCT116_Human1.43208313
49* SUZ12_18555785_Chip-Seq_ESCs_Mouse1.42950878
50ZNF217_24962896_ChIP-Seq_MCF-7_Human1.42544184
51AHR_22903824_ChIP-Seq_MCF-7_Human1.42138117
52* P53_22387025_ChIP-Seq_ESCs_Mouse1.42080954
53TCF4_23295773_ChIP-Seq_U87_Human1.41016619
54SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40920397
55ARNT_22903824_ChIP-Seq_MCF-7_Human1.40187784
56MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.39862979
57FUS_26573619_Chip-Seq_HEK293_Human1.38761001
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.37878738
59TCF4_18268006_ChIP-ChIP_LS174T_Human1.37493240
60* CMYC_18555785_Chip-Seq_ESCs_Mouse1.36497343
61JARID2_20064375_ChIP-Seq_MESCs_Mouse1.34868280
62RUNX_20019798_ChIP-Seq_JUKART_Human1.33940517
63EWS_26573619_Chip-Seq_HEK293_Human1.33177850
64CBX2_27304074_Chip-Seq_ESCs_Mouse1.32425253
65TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31895330
66* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.31866857
67RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.31108026
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.29788829
69* STAT3_18555785_Chip-Seq_ESCs_Mouse1.29174723
70* P300_18555785_Chip-Seq_ESCs_Mouse1.28297843
71FLI1_21867929_ChIP-Seq_TH2_Mouse1.27960437
72PRDM14_20953172_ChIP-Seq_ESCs_Human1.27660026
73* NMYC_18555785_Chip-Seq_ESCs_Mouse1.27171015
74ER_23166858_ChIP-Seq_MCF-7_Human1.26742353
75* OCT4_18555785_Chip-Seq_ESCs_Mouse1.26460676
76* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.26167078
77RNF2_27304074_Chip-Seq_ESCs_Mouse1.25379468
78STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.24858433
79CTBP1_25329375_ChIP-Seq_LNCAP_Human1.22749368
80CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22231322
81RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.20904804
82* SOX2_18555785_Chip-Seq_ESCs_Mouse1.20713885
83* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.19496895
84BMI1_23680149_ChIP-Seq_NPCS_Mouse1.18881520
85P53_22127205_ChIP-Seq_FIBROBLAST_Human1.18736177
86CDX2_19796622_ChIP-Seq_MESCs_Mouse1.18547695
87EZH2_27304074_Chip-Seq_ESCs_Mouse1.18423410
88* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.17112623
89NR3C1_21868756_ChIP-Seq_MCF10A_Human1.16432287
90RNF2_27304074_Chip-Seq_NSC_Mouse1.16265596
91* PU1_27457419_Chip-Seq_LIVER_Mouse1.15282746
92PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.14348564
93CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13680893
94EED_16625203_ChIP-ChIP_MESCs_Mouse1.12965411
95SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.12876961
96RUNX2_22187159_ChIP-Seq_PCA_Human1.12872811
97CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.12347815
98TCF4_22108803_ChIP-Seq_LS180_Human1.12037461
99* ESRRB_18555785_Chip-Seq_ESCs_Mouse1.11976446
100* ZFX_18555785_Chip-Seq_ESCs_Mouse1.11894443
101AR_25329375_ChIP-Seq_VCAP_Human1.11286636
102* CTCF_18555785_Chip-Seq_ESCs_Mouse1.11027260
103SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10829605
104TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.10308259
105SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.10304919
106* KLF4_18555785_Chip-Seq_ESCs_Mouse1.10038950
107FOXM1_26456572_ChIP-Seq_MCF-7_Human1.09995083
108POU5F1_16153702_ChIP-ChIP_HESCs_Human1.09673817
109SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.08811610
110HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.07956003
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07830538
112KDM2B_26808549_Chip-Seq_REH_Human1.07757790
113* CRX_20693478_ChIP-Seq_RETINA_Mouse1.07683226
114BCAT_22108803_ChIP-Seq_LS180_Human1.07380071
115TBL1_22424771_ChIP-Seq_293T_Human1.07183585
116SOX2_21211035_ChIP-Seq_LN229_Gbm1.06834707
117CTNNB1_20460455_ChIP-Seq_HCT116_Human1.06639420
118TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.05594745
119SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.05329534
120EZH2_18974828_ChIP-Seq_MESCs_Mouse1.04809433
121RNF2_18974828_ChIP-Seq_MESCs_Mouse1.04809433
122ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.04429599
123* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04399899
124STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.03850824
125MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.02292227
126SMAD4_21741376_ChIP-Seq_EPCs_Human0.97969353
127IRF1_19129219_ChIP-ChIP_H3396_Human0.97863448
128RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.97222257
129NRF2_20460467_ChIP-Seq_MEFs_Mouse0.97031305
130NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.97031305
131* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.96714787
132CDX2_22108803_ChIP-Seq_LS180_Human0.96187564
133KLF5_20875108_ChIP-Seq_MESCs_Mouse0.95879623

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation6.91954259
2MP0006292_abnormal_olfactory_placode2.93411853
3MP0003787_abnormal_imprinting2.91947219
4MP0005409_darkened_coat_color2.89656197
5MP0000566_synostosis2.59670707
6MP0000015_abnormal_ear_pigmentation2.56036129
7MP0005174_abnormal_tail_pigmentation2.36874059
8MP0002009_preneoplasia2.28892898
9MP0002102_abnormal_ear_morphology2.24197113
10MP0001188_hyperpigmentation2.24036721
11MP0005551_abnormal_eye_electrophysiolog2.14166819
12MP0004130_abnormal_muscle_cell1.98217931
13MP0005423_abnormal_somatic_nervous1.96715013
14MP0003195_calcinosis1.92162669
15MP0003136_yellow_coat_color1.73774374
16MP0003121_genomic_imprinting1.73219006
17MP0000383_abnormal_hair_follicle1.71095067
18MP0008995_early_reproductive_senescence1.63659508
19MP0005253_abnormal_eye_physiology1.61180335
20MP0005171_absent_coat_pigmentation1.60221789
21MP0005645_abnormal_hypothalamus_physiol1.59996064
22MP0000778_abnormal_nervous_system1.59737642
23MP0006072_abnormal_retinal_apoptosis1.52049576
24MP0003724_increased_susceptibility_to1.49997959
25MP0003890_abnormal_embryonic-extraembry1.48296691
26MP0008057_abnormal_DNA_replication1.48234668
27MP0003646_muscle_fatigue1.48181470
28MP0004381_abnormal_hair_follicle1.46009933
29MP0002095_abnormal_skin_pigmentation1.45604037
30MP0005075_abnormal_melanosome_morpholog1.45512601
31MP0001486_abnormal_startle_reflex1.44844382
32MP0001984_abnormal_olfaction1.41905018
33MP0008058_abnormal_DNA_repair1.38779635
34MP0002938_white_spotting1.37008292
35MP0005248_abnormal_Harderian_gland1.36824590
36MP0005310_abnormal_salivary_gland1.36788708
37MP0004043_abnormal_pH_regulation1.33628610
38MP0002177_abnormal_outer_ear1.29757242
39MP0003950_abnormal_plasma_membrane1.29288911
40MP0002928_abnormal_bile_duct1.29015367
41MP0003045_fibrosis1.28733130
42MP0004142_abnormal_muscle_tone1.28043256
43MP0003937_abnormal_limbs/digits/tail_de1.24308390
44MP0008877_abnormal_DNA_methylation1.24083457
45MP0000631_abnormal_neuroendocrine_gland1.22604486
46MP0004484_altered_response_of1.18321671
47MP0003935_abnormal_craniofacial_develop1.16409060
48MP0005391_vision/eye_phenotype1.15333008
49MP0002638_abnormal_pupillary_reflex1.14648023
50MP0003567_abnormal_fetal_cardiomyocyte1.13470601
51MP0002277_abnormal_respiratory_mucosa1.12287014
52MP0000371_diluted_coat_color1.12090018
53MP0002075_abnormal_coat/hair_pigmentati1.11179480
54MP0003763_abnormal_thymus_physiology1.10676982
55MP0010678_abnormal_skin_adnexa1.10314104
56MP0001293_anophthalmia1.09205751
57MP0002166_altered_tumor_susceptibility1.08018469
58MP0002396_abnormal_hematopoietic_system1.07290198
59MP0005503_abnormal_tendon_morphology1.04292902
60MP0005386_behavior/neurological_phenoty1.04098856
61MP0004924_abnormal_behavior1.04098856
62MP0001186_pigmentation_phenotype1.03548583
63MP0003632_abnormal_nervous_system1.02694445
64MP0000579_abnormal_nail_morphology1.01972155
65MP0001324_abnormal_eye_pigmentation1.01289135
66MP0001299_abnormal_eye_distance/1.00221289
67MP0002138_abnormal_hepatobiliary_system0.99842178
68MP0005195_abnormal_posterior_eye0.98337741
69MP0003385_abnormal_body_wall0.98292127
70MP0000428_abnormal_craniofacial_morphol0.97868281
71MP0010094_abnormal_chromosome_stability0.97207911
72MP0009115_abnormal_fat_cell0.97180196
73MP0008961_abnormal_basal_metabolism0.96795357
74MP0004808_abnormal_hematopoietic_stem0.96659951
75MP0002006_tumorigenesis0.95944300
76MP0003755_abnormal_palate_morphology0.95088757
77MP0003690_abnormal_glial_cell0.94802902
78MP0001986_abnormal_taste_sensitivity0.94619352
79MP0004145_abnormal_muscle_electrophysio0.93215671
80MP0001968_abnormal_touch/_nociception0.92121316
81MP0000432_abnormal_head_morphology0.91596400
82MP0005646_abnormal_pituitary_gland0.91254500
83MP0001502_abnormal_circadian_rhythm0.91176474
84MP0002233_abnormal_nose_morphology0.90907205
85MP0000427_abnormal_hair_cycle0.90507383
86MP0005187_abnormal_penis_morphology0.89826123
87MP0002909_abnormal_adrenal_gland0.87307867
88MP0001501_abnormal_sleep_pattern0.87141023
89MP0009046_muscle_twitch0.85967388
90MP0005499_abnormal_olfactory_system0.85602559
91MP0005394_taste/olfaction_phenotype0.85602559
92MP0003943_abnormal_hepatobiliary_system0.85334847
93MP0003221_abnormal_cardiomyocyte_apopto0.84877016
94MP0005220_abnormal_exocrine_pancreas0.83735418
95MP0003252_abnormal_bile_duct0.83619479
96MP0004084_abnormal_cardiac_muscle0.82937842
97MP0003941_abnormal_skin_development0.82544333
98MP0001919_abnormal_reproductive_system0.82284400
99MP0002116_abnormal_craniofacial_bone0.81906084
100MP0009745_abnormal_behavioral_response0.81518410
101MP0003122_maternal_imprinting0.80731068
102MP0005670_abnormal_white_adipose0.80262960
103MP0001286_abnormal_eye_development0.80065775
104MP0009703_decreased_birth_body0.79320777
105MP0001835_abnormal_antigen_presentation0.78368224
106MP0003861_abnormal_nervous_system0.78321304
107MP0002735_abnormal_chemical_nociception0.78104374
108MP0003656_abnormal_erythrocyte_physiolo0.77667887
109MP0003938_abnormal_ear_development0.77285232
110MP0002109_abnormal_limb_morphology0.76993952
111MP0000955_abnormal_spinal_cord0.76921822
112MP0002752_abnormal_somatic_nervous0.76149447
113MP0004134_abnormal_chest_morphology0.76049110
114MP0001800_abnormal_humoral_immune0.75678576
115MP0002168_other_aberrant_phenotype0.75231096
116MP0002837_dystrophic_cardiac_calcinosis0.74841930
117MP0002063_abnormal_learning/memory/cond0.74262339
118MP0002249_abnormal_larynx_morphology0.74207233
119MP0005076_abnormal_cell_differentiation0.74019345
120MP0004742_abnormal_vestibular_system0.73719582
121MP0009250_abnormal_appendicular_skeleto0.73664212
122MP0010030_abnormal_orbit_morphology0.72766264
123MP0003878_abnormal_ear_physiology0.72670816
124MP0005377_hearing/vestibular/ear_phenot0.72670816
125MP0003631_nervous_system_phenotype0.72315083
126MP0000026_abnormal_inner_ear0.71071781
127MP0002557_abnormal_social/conspecific_i0.70991833
128MP0001485_abnormal_pinna_reflex0.70474656
129MP0005266_abnormal_metabolism0.69895521
130MP0003633_abnormal_nervous_system0.69469355
131MP0002332_abnormal_exercise_endurance0.69463186
132MP0002184_abnormal_innervation0.68843920
133MP0000372_irregular_coat_pigmentation0.67576315
134MP0005387_immune_system_phenotype0.67576088
135MP0001790_abnormal_immune_system0.67576088
136MP0004883_abnormal_blood_vessel0.67199819
137MP0004885_abnormal_endolymph0.66804817
138MP0008789_abnormal_olfactory_epithelium0.66443836
139MP0005671_abnormal_response_to0.66436922
140MP0002229_neurodegeneration0.66086637
141MP0002108_abnormal_muscle_morphology0.65593796
142MP0000703_abnormal_thymus_morphology0.65165577
143MP0002067_abnormal_sensory_capabilities0.65090157
144MP0002092_abnormal_eye_morphology0.64719192
145MP0002064_seizures0.64459981
146MP0003635_abnormal_synaptic_transmissio0.64440918
147MP0000647_abnormal_sebaceous_gland0.64234337
148MP0002882_abnormal_neuron_morphology0.64110407
149MP0006276_abnormal_autonomic_nervous0.63118782
150MP0004215_abnormal_myocardial_fiber0.61240649
151MP0003172_abnormal_lysosome_physiology0.60256445
152MP0003866_abnormal_defecation0.59829548

Predicted human phenotypes

RankGene SetZ-score
1Hyperventilation (HP:0002883)3.70349797
2Congenital stationary night blindness (HP:0007642)3.59313068
3Chromosomal breakage induced by crosslinking agents (HP:0003221)3.46069481
4Abnormality of the fingertips (HP:0001211)3.32566333
5Progressive cerebellar ataxia (HP:0002073)3.30424403
6Pancreatic cysts (HP:0001737)3.18576269
7Chromsome breakage (HP:0040012)3.14509754
8Gaze-evoked nystagmus (HP:0000640)3.11793070
9Elfin facies (HP:0004428)2.99849145
10Renovascular hypertension (HP:0100817)2.89208326
11Midline defect of the nose (HP:0004122)2.81839301
12Febrile seizures (HP:0002373)2.81191897
13Short 4th metacarpal (HP:0010044)2.76210644
14Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.76210644
15Abnormality of the nasal septum (HP:0000419)2.73275804
16Lip pit (HP:0100267)2.69851818
17Flat cornea (HP:0007720)2.56708174
18Pancreatic fibrosis (HP:0100732)2.55988562
19Overriding aorta (HP:0002623)2.53627838
20Intestinal atresia (HP:0011100)2.51954933
21Abnormality of T cell number (HP:0011839)2.48820985
22Abnormality of the renal cortex (HP:0011035)2.48135657
23Abnormality of the diencephalon (HP:0010662)2.42881932
24Abnormality of the renal medulla (HP:0100957)2.37778104
25Ectopic kidney (HP:0000086)2.36502527
26Nephronophthisis (HP:0000090)2.36407578
27Heterotopia (HP:0002282)2.34534532
28Molar tooth sign on MRI (HP:0002419)2.32276142
29Abnormality of midbrain morphology (HP:0002418)2.32276142
30Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.32021156
31Hypochromic microcytic anemia (HP:0004840)2.31308790
32Hyperacusis (HP:0010780)2.28255532
33Abnormality of the ischium (HP:0003174)2.26459875
34True hermaphroditism (HP:0010459)2.26049689
35Abnormality of the carotid arteries (HP:0005344)2.24497094
36Poor coordination (HP:0002370)2.23810677
37Aqueductal stenosis (HP:0002410)2.20413056
38Truncal obesity (HP:0001956)2.19563668
39Abnormality of incisor morphology (HP:0011063)2.18176829
40Renal duplication (HP:0000075)2.15124796
41Absent frontal sinuses (HP:0002688)2.15073380
42Trigonocephaly (HP:0000243)2.14079748
43Tubulointerstitial nephritis (HP:0001970)2.13691194
44Thyroid carcinoma (HP:0002890)2.11105031
45Anal stenosis (HP:0002025)2.10380892
46Urinary bladder sphincter dysfunction (HP:0002839)2.09444180
47Medial flaring of the eyebrow (HP:0010747)2.07524722
48Narrow palate (HP:0000189)2.04233143
49Aplasia/Hypoplasia of the tibia (HP:0005772)2.03931844
50Prostate neoplasm (HP:0100787)2.03695526
51Volvulus (HP:0002580)2.02885725
52Obsessive-compulsive behavior (HP:0000722)2.02671941
53Progressive inability to walk (HP:0002505)2.01566946
54Dyschromatopsia (HP:0007641)2.01298267
55Abnormal delayed hypersensitivity skin test (HP:0002963)2.00862518
56Deep philtrum (HP:0002002)1.98748808
57Hematochezia (HP:0002573)1.98368501
58Chronic hepatic failure (HP:0100626)1.98250790
59Long eyelashes (HP:0000527)1.96905244
60Chorioretinal atrophy (HP:0000533)1.96829817
61Macroorchidism (HP:0000053)1.93688349
62Excessive salivation (HP:0003781)1.92740077
63Drooling (HP:0002307)1.92740077
64Postural instability (HP:0002172)1.92685813
65Genital tract atresia (HP:0001827)1.92494255
66Papillary thyroid carcinoma (HP:0002895)1.90785301
67Hepatoblastoma (HP:0002884)1.88972576
68Hip dysplasia (HP:0001385)1.88837829
69Aplasia/Hypoplasia of the uvula (HP:0010293)1.88251421
70Decreased central vision (HP:0007663)1.87322472
71Protruding tongue (HP:0010808)1.85236069
72Clubbing of toes (HP:0100760)1.85011104
73Abnormality of the renal collecting system (HP:0004742)1.84990856
74Genetic anticipation (HP:0003743)1.84759310
75Vaginal atresia (HP:0000148)1.84488040
76Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.84436558
77Degeneration of the lateral corticospinal tracts (HP:0002314)1.84436558
78Gait imbalance (HP:0002141)1.83758776
79Agammaglobulinemia (HP:0004432)1.83674284
80Thyroiditis (HP:0100646)1.83120474
81Widely spaced teeth (HP:0000687)1.83074471
82Hypoplastic iliac wings (HP:0002866)1.81441746
83Bony spicule pigmentary retinopathy (HP:0007737)1.80544313
84Abnormality of DNA repair (HP:0003254)1.80401662
85Impaired vibratory sensation (HP:0002495)1.79003621
86Congenital primary aphakia (HP:0007707)1.78275211
87Duplicated collecting system (HP:0000081)1.76409603
88Depressed nasal tip (HP:0000437)1.75616424
89Cystic liver disease (HP:0006706)1.75376183
90Increased corneal curvature (HP:0100692)1.75228115
91Keratoconus (HP:0000563)1.75228115
92Renal cortical cysts (HP:0000803)1.74972729
93Abnormal hair whorl (HP:0010721)1.74502680
94Clumsiness (HP:0002312)1.73739171
95Patellar dislocation (HP:0002999)1.73450739
96Pheochromocytoma (HP:0002666)1.73424511
97Cupped ear (HP:0000378)1.71972986
98Large for gestational age (HP:0001520)1.71626342
99Abnormality of the parietal bone (HP:0002696)1.71327918
100Highly arched eyebrow (HP:0002553)1.70650040
101Abnormality of the incisor (HP:0000676)1.70240662
102Optic neuritis (HP:0100653)1.69714560
103Retrobulbar optic neuritis (HP:0100654)1.69714560
104Stomatitis (HP:0010280)1.69237877
105Subacute progressive viral hepatitis (HP:0006572)1.68079285
106Increased nuchal translucency (HP:0010880)1.68034394
107Inappropriate behavior (HP:0000719)1.66917006
108Panhypogammaglobulinemia (HP:0003139)1.66502083
109Neoplasm of the tracheobronchial system (HP:0100552)1.66123439
110Spontaneous hematomas (HP:0007420)1.66078249
111Hypothermia (HP:0002045)1.65289639
112Nephrogenic diabetes insipidus (HP:0009806)1.64975297
113Recurrent fungal infections (HP:0002841)1.64905391
114Short chin (HP:0000331)1.64831550
115Hypoplastic ischia (HP:0003175)1.64384035
116Abnormal biliary tract morphology (HP:0012440)1.63959953
117Abnormality of chromosome stability (HP:0003220)1.63864731
118Cutaneous finger syndactyly (HP:0010554)1.63548063
119Neonatal hypoglycemia (HP:0001998)1.63457786
120Aplasia cutis congenita (HP:0001057)1.63091353
121Abnormality of the 4th metacarpal (HP:0010012)1.62906567
122Cystic hygroma (HP:0000476)1.62345896
123Fair hair (HP:0002286)1.61069182
124Hypoplasia of the maxilla (HP:0000327)1.60575265
125Short foot (HP:0001773)1.58715737
126Recurrent cutaneous fungal infections (HP:0011370)1.58622384
127Chronic mucocutaneous candidiasis (HP:0002728)1.58622384
128Recurrent bacterial skin infections (HP:0005406)1.58142559
129Dysmetric saccades (HP:0000641)1.58120208
130Supernumerary ribs (HP:0005815)1.57914772
131Colon cancer (HP:0003003)1.56886592
132Hypoplasia of the thymus (HP:0000778)1.54982245
133Blue irides (HP:0000635)1.54941171
134Inability to walk (HP:0002540)1.54657835
135Tented upper lip vermilion (HP:0010804)1.54578575
136Hypoplastic labia majora (HP:0000059)1.54241950
137Absent speech (HP:0001344)1.54006568
138Stomach cancer (HP:0012126)1.53983842
139Abnormality of the corticospinal tract (HP:0002492)1.53747736
140Severe combined immunodeficiency (HP:0004430)1.53726088
141Abnormality of the antihelix (HP:0009738)1.53462922
142Abnormality of salivation (HP:0100755)1.53307596
143Macrotia (HP:0000400)1.53247265
144Meckel diverticulum (HP:0002245)1.52375467
145Vitreoretinal degeneration (HP:0000655)1.52044502
146Generalized hypopigmentation of hair (HP:0011358)1.51669221
147Pigmentary retinal degeneration (HP:0001146)1.50961106
148Toxemia of pregnancy (HP:0100603)1.50795902
149Neoplasm of the adrenal cortex (HP:0100641)1.50674937
150Acute lymphatic leukemia (HP:0006721)1.49818554
151Cutaneous syndactyly (HP:0012725)1.49429358
152Vesicoureteral reflux (HP:0000076)1.48931609
153Exotropia (HP:0000577)1.47712806
154Chronic diarrhea (HP:0002028)1.47159966
155Increased number of teeth (HP:0011069)1.47106668
156Neoplasm of the oral cavity (HP:0100649)1.46777344
157Oligodactyly (hands) (HP:0001180)1.46458447
158Insomnia (HP:0100785)1.46064138
159Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.45175881
160Pendular nystagmus (HP:0012043)1.44571184
161Abnormality of the ileum (HP:0001549)1.43861065
162Broad-based gait (HP:0002136)1.43632144
163Urethral obstruction (HP:0000796)1.43568361
164Attenuation of retinal blood vessels (HP:0007843)1.42330149
165Bowel diverticulosis (HP:0005222)1.42201622
166Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.41917382
167Everted lower lip vermilion (HP:0000232)1.41694079
168T lymphocytopenia (HP:0005403)1.41456367
169Acute myeloid leukemia (HP:0004808)1.41381635

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BRD43.12791871
2CDK122.66018742
3LATS12.49954635
4CAMK1G2.48827451
5ACVR1B2.39115581
6CAMK1D2.36337978
7WNK32.11652770
8INSRR2.06316551
9SGK22.05388752
10MKNK21.85089290
11MARK11.80936969
12YES11.80336601
13EPHA31.80187321
14ZAK1.79416209
15CAMKK21.79262618
16FGFR21.72123829
17GRK11.64950330
18TAOK31.63938978
19TXK1.61928843
20SIK21.59470073
21CASK1.58869852
22SGK31.55260892
23TNIK1.53975807
24FGFR31.48381768
25MAP3K131.45295688
26BLK1.42093885
27EIF2AK21.39706494
28MAP3K141.39175082
29MAPK131.35552167
30ERBB31.35054926
31CDK91.33792448
32MAP2K71.31461891
33NUAK11.30160756
34PKN11.29408427
35CDK31.29084609
36NTRK31.28943075
37PIK3CG1.23773640
38SGK4941.21141590
39SGK2231.21141590
40JAK11.19027532
41OXSR11.17306135
42MARK21.17190784
43CLK11.17068348
44MKNK11.16848709
45STK391.15855911
46STK31.14634056
47SRPK11.14046125
48AKT31.12164259
49FRK1.07095354
50PAK31.06494180
51MAP2K41.03127884
52MAPK71.03051037
53NTRK21.01725456
54MAP3K40.99173880
55MAP3K20.98174027
56OBSCN0.97143409
57KSR10.96872350
58SIK30.96731826
59BTK0.94794797
60WNK10.93602608
61PDGFRB0.93390463
62PKN20.92567027
63BMPR1B0.89774690
64PRKAA20.87927958
65SGK10.87729117
66NEK60.87076528
67CHUK0.84166394
68SIK10.84076356
69CSNK1A1L0.83492645
70PRPF4B0.83327732
71STK38L0.83233400
72DYRK1A0.80418545
73RIPK40.78953191
74TGFBR10.78897250
75IRAK40.77619305
76JAK30.77006878
77MARK30.76664750
78SYK0.76539799
79TAF10.76065457
80RET0.75930286
81PIK3CA0.73644947
82HCK0.73474202
83PINK10.71518409
84ATR0.71469497
85TNK20.70427819
86IRAK20.70030396
87FES0.69752858
88PTK2B0.69717222
89CHEK20.69475859
90IKBKE0.68968576
91MAP3K70.68880249
92PRKD20.68408585
93CAMKK10.66954358
94MELK0.65967453
95JAK20.65960118
96NLK0.65843183
97TRPM70.65159683
98PLK40.63937752
99ADRBK20.63425863
100ATM0.63326637
101MAPK100.61825132
102STK380.59001778
103IRAK10.58511245
104BRSK20.58358116
105PRKCQ0.56479016
106FER0.56339969
107BCR0.56323898
108CAMK40.56298021
109LCK0.56175746
110CDC42BPA0.55979351
111ERBB20.55779008
112CSNK1D0.55660421
113TRIM280.54291729
114PRKAA10.54088156
115DMPK0.53098811
116CSK0.52985430
117MTOR0.52448114
118GSK3B0.51844090
119STK40.51719482
120MAP3K60.50906192
121WNK40.50830362
122IRAK30.50420325
123MAP4K20.50255841
124TGFBR20.50029723
125TYK20.49474529
126MAPK120.49382963
127STK110.49090188
128TEC0.48805290
129IKBKB0.47893977
130MAPK140.47726106
131MAPK80.47243532
132FGR0.47187855
133HIPK20.46976643
134LYN0.46698385
135MAP4K10.46448359
136FLT30.43635466
137ITK0.43548093
138PRKCH0.42636355
139CDK10.42264713
140AKT10.41281808
141CSF1R0.41175923
142RPS6KB10.40027027
143PIM10.39746318
144DYRK30.39128115

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047442.86984997
2Fanconi anemia pathway_Homo sapiens_hsa034601.62464443
3Lysine degradation_Homo sapiens_hsa003101.55750882
4Primary immunodeficiency_Homo sapiens_hsa053401.54362463
5ABC transporters_Homo sapiens_hsa020101.52066964
6Nicotine addiction_Homo sapiens_hsa050331.49311379
7Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.48655621
8Phosphatidylinositol signaling system_Homo sapiens_hsa040701.36241921
9NF-kappa B signaling pathway_Homo sapiens_hsa040641.35256780
10Morphine addiction_Homo sapiens_hsa050321.30474154
11Dorso-ventral axis formation_Homo sapiens_hsa043201.25644554
12Basal cell carcinoma_Homo sapiens_hsa052171.21244895
13T cell receptor signaling pathway_Homo sapiens_hsa046601.20087106
14Non-homologous end-joining_Homo sapiens_hsa034501.19177481
15B cell receptor signaling pathway_Homo sapiens_hsa046621.15620261
16Regulation of autophagy_Homo sapiens_hsa041401.15238069
17Platelet activation_Homo sapiens_hsa046111.14883056
18Ether lipid metabolism_Homo sapiens_hsa005651.14497878
19Axon guidance_Homo sapiens_hsa043601.14166832
20MicroRNAs in cancer_Homo sapiens_hsa052061.13288205
21Glutamatergic synapse_Homo sapiens_hsa047241.11499909
22Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.11168834
23Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.11020845
24Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.09962053
25Circadian rhythm_Homo sapiens_hsa047101.09231480
26Transcriptional misregulation in cancer_Homo sapiens_hsa052021.08115390
27Olfactory transduction_Homo sapiens_hsa047401.06441876
28Long-term depression_Homo sapiens_hsa047301.06109237
29Type II diabetes mellitus_Homo sapiens_hsa049301.04147075
30Endometrial cancer_Homo sapiens_hsa052131.03692038
31ErbB signaling pathway_Homo sapiens_hsa040121.03632256
32Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.03008656
33Carbohydrate digestion and absorption_Homo sapiens_hsa049731.01639359
34Butanoate metabolism_Homo sapiens_hsa006501.01628751
35Choline metabolism in cancer_Homo sapiens_hsa052311.01475687
36Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.01204502
37Viral myocarditis_Homo sapiens_hsa054161.01171598
38Colorectal cancer_Homo sapiens_hsa052101.00675914
39Ovarian steroidogenesis_Homo sapiens_hsa049131.00436252
40alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.98687763
41Wnt signaling pathway_Homo sapiens_hsa043100.98375437
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.98053131
43Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.97971988
44Linoleic acid metabolism_Homo sapiens_hsa005910.97276532
45Hematopoietic cell lineage_Homo sapiens_hsa046400.97139836
46Chemokine signaling pathway_Homo sapiens_hsa040620.96754020
47Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96603085
48Inositol phosphate metabolism_Homo sapiens_hsa005620.96534562
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.96520642
50Chronic myeloid leukemia_Homo sapiens_hsa052200.96501035
51Pancreatic cancer_Homo sapiens_hsa052120.96394695
52Prostate cancer_Homo sapiens_hsa052150.95934228
53Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.95086581
54Circadian entrainment_Homo sapiens_hsa047130.94118376
55Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.93817763
56Nitrogen metabolism_Homo sapiens_hsa009100.93048120
57Adherens junction_Homo sapiens_hsa045200.92315707
58FoxO signaling pathway_Homo sapiens_hsa040680.91619194
59MAPK signaling pathway_Homo sapiens_hsa040100.91052680
60cAMP signaling pathway_Homo sapiens_hsa040240.90912549
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90747901
62Notch signaling pathway_Homo sapiens_hsa043300.88734816
63Taste transduction_Homo sapiens_hsa047420.88288161
64Intestinal immune network for IgA production_Homo sapiens_hsa046720.87300119
65Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.86852147
66Dilated cardiomyopathy_Homo sapiens_hsa054140.86759667
67Insulin resistance_Homo sapiens_hsa049310.86574377
68Measles_Homo sapiens_hsa051620.86420117
69Vascular smooth muscle contraction_Homo sapiens_hsa042700.86344900
70Jak-STAT signaling pathway_Homo sapiens_hsa046300.86009740
71Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.84979955
72Herpes simplex infection_Homo sapiens_hsa051680.84967793
73Osteoclast differentiation_Homo sapiens_hsa043800.84354966
74Cholinergic synapse_Homo sapiens_hsa047250.82155408
75Dopaminergic synapse_Homo sapiens_hsa047280.81821899
76Phospholipase D signaling pathway_Homo sapiens_hsa040720.81190986
77Renal cell carcinoma_Homo sapiens_hsa052110.80961521
78Small cell lung cancer_Homo sapiens_hsa052220.80389752
79cGMP-PKG signaling pathway_Homo sapiens_hsa040220.80209540
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.78453162
81Glioma_Homo sapiens_hsa052140.78248556
82Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.77785388
83Pathways in cancer_Homo sapiens_hsa052000.77181361
84Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.76756991
85Serotonergic synapse_Homo sapiens_hsa047260.76435528
86Long-term potentiation_Homo sapiens_hsa047200.75570024
87Aldosterone synthesis and secretion_Homo sapiens_hsa049250.75132076
88Autoimmune thyroid disease_Homo sapiens_hsa053200.74542439
89Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.74305078
90Ras signaling pathway_Homo sapiens_hsa040140.74034367
91Prolactin signaling pathway_Homo sapiens_hsa049170.73249882
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72663747
93Renin secretion_Homo sapiens_hsa049240.72430414
94TGF-beta signaling pathway_Homo sapiens_hsa043500.71874891
95Toll-like receptor signaling pathway_Homo sapiens_hsa046200.71776748
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.71747988
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.71724577
98GnRH signaling pathway_Homo sapiens_hsa049120.71523752
99TNF signaling pathway_Homo sapiens_hsa046680.71284228
100Acute myeloid leukemia_Homo sapiens_hsa052210.71014249
101Neurotrophin signaling pathway_Homo sapiens_hsa047220.70910531
102Calcium signaling pathway_Homo sapiens_hsa040200.70248238
103mRNA surveillance pathway_Homo sapiens_hsa030150.69850388
104GABAergic synapse_Homo sapiens_hsa047270.67650450
105Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.67407067
106Hepatitis B_Homo sapiens_hsa051610.67247644
107Hedgehog signaling pathway_Homo sapiens_hsa043400.67223625
108Rap1 signaling pathway_Homo sapiens_hsa040150.66963482
109Oxytocin signaling pathway_Homo sapiens_hsa049210.66710577
110Melanoma_Homo sapiens_hsa052180.66258592
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.66110971
112Toxoplasmosis_Homo sapiens_hsa051450.66091782
113HTLV-I infection_Homo sapiens_hsa051660.65991014
114Estrogen signaling pathway_Homo sapiens_hsa049150.65852684
115Salivary secretion_Homo sapiens_hsa049700.65431507
116Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.65252014
117Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.64967019
118RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64427563
119mTOR signaling pathway_Homo sapiens_hsa041500.62636531
120Alcoholism_Homo sapiens_hsa050340.62227759
121Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.61654853
122Basal transcription factors_Homo sapiens_hsa030220.61311921
123Amphetamine addiction_Homo sapiens_hsa050310.61252659
124ECM-receptor interaction_Homo sapiens_hsa045120.61248999
125Maturity onset diabetes of the young_Homo sapiens_hsa049500.61053215
126Non-small cell lung cancer_Homo sapiens_hsa052230.60975018
127Insulin secretion_Homo sapiens_hsa049110.60839664
128Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.60763346
129Melanogenesis_Homo sapiens_hsa049160.60626330
130Influenza A_Homo sapiens_hsa051640.60068228
131Fatty acid biosynthesis_Homo sapiens_hsa000610.57615174
132Leishmaniasis_Homo sapiens_hsa051400.57074717
133Tuberculosis_Homo sapiens_hsa051520.56984287

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