ZBTB39

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)5.29143431
2regulation of histone H3-K9 methylation (GO:0051570)4.34156228
3mitotic chromosome condensation (GO:0007076)4.33019910
4protein localization to kinetochore (GO:0034501)4.14234341
5protein localization to chromosome, centromeric region (GO:0071459)4.09247542
6pore complex assembly (GO:0046931)3.94730874
7paraxial mesoderm development (GO:0048339)3.79840638
8heterochromatin organization (GO:0070828)3.74950792
9DNA replication checkpoint (GO:0000076)3.68938856
10DNA strand elongation involved in DNA replication (GO:0006271)3.68301144
11hippo signaling (GO:0035329)3.64818055
12cytoplasmic mRNA processing body assembly (GO:0033962)3.63293104
13DNA topological change (GO:0006265)3.61898025
14DNA strand elongation (GO:0022616)3.59899125
15chromatin remodeling at centromere (GO:0031055)3.53924573
16mitotic metaphase plate congression (GO:0007080)3.52993739
17regulation of translational fidelity (GO:0006450)3.52627854
18CENP-A containing nucleosome assembly (GO:0034080)3.47879928
19establishment of integrated proviral latency (GO:0075713)3.47680093
20protein complex localization (GO:0031503)3.45451073
21positive regulation of histone deacetylation (GO:0031065)3.35586791
22ATP-dependent chromatin remodeling (GO:0043044)3.35212385
23regulation of chromatin binding (GO:0035561)3.33095607
24sister chromatid segregation (GO:0000819)3.31232988
25mitotic sister chromatid segregation (GO:0000070)3.30300432
26regulation of hippo signaling (GO:0035330)3.29700639
27glucocorticoid receptor signaling pathway (GO:0042921)3.29111121
28DNA replication-independent nucleosome organization (GO:0034724)3.28407630
29DNA replication-independent nucleosome assembly (GO:0006336)3.28407630
30RNA stabilization (GO:0043489)3.23608854
31mRNA stabilization (GO:0048255)3.23608854
32nuclear pore organization (GO:0006999)3.19085494
33histone exchange (GO:0043486)3.17587522
34nuclear pore complex assembly (GO:0051292)3.15142374
35DNA replication initiation (GO:0006270)3.15126314
36regulation of gene silencing by RNA (GO:0060966)3.12362787
37regulation of posttranscriptional gene silencing (GO:0060147)3.12362787
38regulation of gene silencing by miRNA (GO:0060964)3.12362787
39chromosome condensation (GO:0030261)3.12074835
40positive regulation of chromosome segregation (GO:0051984)3.11904842
41chromatin assembly or disassembly (GO:0006333)3.09715778
42cellular protein complex localization (GO:0034629)3.09694170
43DNA synthesis involved in DNA repair (GO:0000731)3.08825214
44nuclear envelope disassembly (GO:0051081)3.08503915
45membrane disassembly (GO:0030397)3.08503915
46protein-DNA complex disassembly (GO:0032986)3.08392026
47nucleosome disassembly (GO:0006337)3.08392026
48DNA replication-dependent nucleosome assembly (GO:0006335)3.08196583
49DNA replication-dependent nucleosome organization (GO:0034723)3.08196583
50regulation of RNA export from nucleus (GO:0046831)3.07250884
51meiotic chromosome segregation (GO:0045132)3.07148411
52regulation of fatty acid beta-oxidation (GO:0031998)3.06921318
53regulation of cholesterol homeostasis (GO:2000188)3.06702218
54embryonic retina morphogenesis in camera-type eye (GO:0060059)3.06553757
55embryonic foregut morphogenesis (GO:0048617)3.06117151
56positive regulation of fatty acid beta-oxidation (GO:0032000)3.04109414
57regulation of DNA methylation (GO:0044030)3.03030902
58regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.00936291
59NLS-bearing protein import into nucleus (GO:0006607)3.00488848
60telomere maintenance via semi-conservative replication (GO:0032201)2.99652976
61negative regulation of chromosome segregation (GO:0051985)2.97300875
62negative regulation of histone methylation (GO:0031061)2.96886555
63insulin-like growth factor receptor signaling pathway (GO:0048009)2.96693546
64regulation of histone methylation (GO:0031060)2.94825672
65regulation of gene silencing (GO:0060968)2.94560161
66regulation of sister chromatid cohesion (GO:0007063)2.93973138
67negative regulation of RNA splicing (GO:0033119)2.93628520
68DNA duplex unwinding (GO:0032508)2.92773440
69polarized epithelial cell differentiation (GO:0030859)2.91997055
70negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.89608143
71negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.89608143
72negative regulation of mitotic sister chromatid segregation (GO:0033048)2.89608143
73negative regulation of mitotic sister chromatid separation (GO:2000816)2.89608143
74negative regulation of sister chromatid segregation (GO:0033046)2.89608143
75formation of translation preinitiation complex (GO:0001731)2.88797341
76trophectodermal cell differentiation (GO:0001829)2.87362514
77positive regulation of SMAD protein import into nucleus (GO:0060391)2.86806338
78regulation of histone H3-K4 methylation (GO:0051569)2.86784081
79gastrulation with mouth forming second (GO:0001702)2.86499705
80regulation of chromatin silencing (GO:0031935)2.86376389
81DNA geometric change (GO:0032392)2.85837327
82regulation of chromosome segregation (GO:0051983)2.85626831
83regulation of centriole replication (GO:0046599)2.85256085
84planar cell polarity pathway involved in neural tube closure (GO:0090179)2.84169642
85positive regulation of cell cycle G2/M phase transition (GO:1902751)2.84137809
86positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.84137809
87metaphase plate congression (GO:0051310)2.84129666
88mitotic sister chromatid cohesion (GO:0007064)2.84104850
89DNA packaging (GO:0006323)2.82482054
90DNA conformation change (GO:0071103)2.80513745
91attachment of spindle microtubules to kinetochore (GO:0008608)2.80226019
92epithelial cell differentiation involved in prostate gland development (GO:0060742)2.79340700
93negative regulation of gene silencing (GO:0060969)2.79270542
94alpha-linolenic acid metabolic process (GO:0036109)2.78611042
95regulation of NFAT protein import into nucleus (GO:0051532)2.76573706
96negative regulation of translation, ncRNA-mediated (GO:0040033)2.76189481
97regulation of translation, ncRNA-mediated (GO:0045974)2.76189481
98negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.76189481
99protein localization to chromosome (GO:0034502)2.76024655
100maturation of SSU-rRNA (GO:0030490)2.75302442
101regulation of sister chromatid segregation (GO:0033045)2.75194955
102regulation of mitotic sister chromatid separation (GO:0010965)2.75194955
103regulation of mitotic sister chromatid segregation (GO:0033047)2.75194955
104regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.75075185
105regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.74630556
106regulation of mitotic metaphase/anaphase transition (GO:0030071)2.74630556
107midgut development (GO:0007494)2.74361294
108mRNA transport (GO:0051028)2.73642942
109peptidyl-lysine dimethylation (GO:0018027)2.73487570
110establishment of apical/basal cell polarity (GO:0035089)2.72368232
111spindle checkpoint (GO:0031577)2.71861793
112telomere maintenance via recombination (GO:0000722)2.71715603
113regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.70240719
114negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.70158737
115regulation of helicase activity (GO:0051095)2.69586996
116mitotic spindle checkpoint (GO:0071174)2.67904677
117mitotic recombination (GO:0006312)2.65491881
118positive regulation of histone methylation (GO:0031062)2.65418108
119folic acid-containing compound biosynthetic process (GO:0009396)2.64879671
120negative regulation of cholesterol transport (GO:0032375)2.64729248
121negative regulation of sterol transport (GO:0032372)2.64729248
122dicarboxylic acid biosynthetic process (GO:0043650)2.64431835
123intracellular estrogen receptor signaling pathway (GO:0030520)2.64000939
124chromatin assembly (GO:0031497)2.63153660
125dorsal/ventral axis specification (GO:0009950)2.62622636
126positive regulation of hormone biosynthetic process (GO:0046886)2.62436475
127histone H3-K36 demethylation (GO:0070544)2.59806465
128glycine metabolic process (GO:0006544)2.57355084
129DNA unwinding involved in DNA replication (GO:0006268)2.56502596
130negative regulation of DNA repair (GO:0045738)2.54712035
131histone H2A monoubiquitination (GO:0035518)2.51084499
132regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.50822345
133anterior/posterior axis specification, embryo (GO:0008595)2.49788507
134urea metabolic process (GO:0019627)2.48833413
135urea cycle (GO:0000050)2.48833413
136serine family amino acid catabolic process (GO:0009071)2.47136639
137regulation of SMAD protein import into nucleus (GO:0060390)2.47122561
138corticosteroid receptor signaling pathway (GO:0031958)2.46572110
139maternal placenta development (GO:0001893)2.45819227
140regulation of nucleobase-containing compound transport (GO:0032239)2.45621972
141lysine catabolic process (GO:0006554)2.45408343
142lysine metabolic process (GO:0006553)2.45408343
143spliceosomal tri-snRNP complex assembly (GO:0000244)2.45374551
144homocysteine metabolic process (GO:0050667)2.43869607
145L-alpha-amino acid transmembrane transport (GO:1902475)2.43323130
146negative regulation of fibrinolysis (GO:0051918)2.43080293
147triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.42219658
148regulation of mRNA stability (GO:0043488)2.41583266
149positive regulation of glycogen biosynthetic process (GO:0045725)2.40689062
150negative regulation of cell size (GO:0045792)2.39302465
151regulation of stem cell maintenance (GO:2000036)2.38468044
152embryonic placenta development (GO:0001892)2.38463223
153regulation of translational termination (GO:0006449)2.38099782
154notochord development (GO:0030903)2.35570582
155mitotic nuclear envelope disassembly (GO:0007077)2.33981721
156negative regulation of lipid transport (GO:0032369)2.32082858
157response to UV-C (GO:0010225)2.31762568
158adherens junction assembly (GO:0034333)2.31210155
159negative regulation of mRNA processing (GO:0050686)2.30691396
160dosage compensation (GO:0007549)2.29738131
161negative regulation of mRNA metabolic process (GO:1903312)2.29645097
162negative regulation of fatty acid biosynthetic process (GO:0045717)2.28846585
163gene silencing (GO:0016458)2.27761105
164kynurenine metabolic process (GO:0070189)2.27453197
165G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071992.26654796
166anatomical structure regression (GO:0060033)2.26454935
167endocardial cushion development (GO:0003197)2.26318981
168histone lysine demethylation (GO:0070076)2.25636950
169neural tube closure (GO:0001843)2.25607251
170positive regulation of gene expression, epigenetic (GO:0045815)2.23824991
171stress granule assembly (GO:0034063)2.22312059
172positive regulation of glycogen metabolic process (GO:0070875)2.22296733
173establishment of monopolar cell polarity (GO:0061162)2.22201700
174establishment or maintenance of monopolar cell polarity (GO:0061339)2.22201700
175establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.21784536
176sulfur amino acid catabolic process (GO:0000098)2.21744031
177chromatin silencing (GO:0006342)2.21627701
178regulation of RNA stability (GO:0043487)2.21585461

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.25475124
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.01010768
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.83244340
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.58327385
5ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.45617273
6MYC_22102868_ChIP-Seq_BL_Human3.27464825
7EGR1_19374776_ChIP-ChIP_THP-1_Human3.20651694
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.89482067
9PPARA_22158963_ChIP-Seq_LIVER_Mouse2.78687649
10* RXR_22158963_ChIP-Seq_LIVER_Mouse2.71423186
11MYC_19079543_ChIP-ChIP_MESCs_Mouse2.68271329
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.54885236
13POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.47698251
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.43766646
15MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.36081355
16LXR_22158963_ChIP-Seq_LIVER_Mouse2.32705632
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.29181862
18ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.28888192
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.23475591
20TCF7_22412390_ChIP-Seq_EML_Mouse2.22338468
21SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.17779558
22KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.14143289
23TP63_17297297_ChIP-ChIP_HaCaT_Human2.13509180
24CLOCK_20551151_ChIP-Seq_293T_Human2.11180768
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.06782036
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.06735791
27MYCN_18555785_ChIP-Seq_MESCs_Mouse2.05590858
28XRN2_22483619_ChIP-Seq_HELA_Human2.03753851
29YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.03549707
30EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.02901388
31TP63_19390658_ChIP-ChIP_HaCaT_Human2.02367947
32TTF2_22483619_ChIP-Seq_HELA_Human2.01848190
33KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.01847165
34KDM2B_26808549_Chip-Seq_DND41_Human1.98526668
35MYC_18358816_ChIP-ChIP_MESCs_Mouse1.96937798
36CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.96310999
37ZFP281_27345836_Chip-Seq_ESCs_Mouse1.91925837
38KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.91066391
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.90317894
40RBPJ_22232070_ChIP-Seq_NCS_Mouse1.90211267
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.89853814
42ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.89260982
43KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.87378519
44NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.85630070
45EST1_17652178_ChIP-ChIP_JURKAT_Human1.85403675
46ZFP281_18757296_ChIP-ChIP_E14_Mouse1.80281909
47POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.78764962
48KDM2B_26808549_Chip-Seq_SUP-B15_Human1.77101060
49SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.77092247
50KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.76499419
51DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.73504863
52TCF3_18692474_ChIP-Seq_MEFs_Mouse1.71733139
53CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.70010137
54ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69377996
55ELK3_25401928_ChIP-Seq_HUVEC_Human1.69247492
56STAT6_21828071_ChIP-Seq_BEAS2B_Human1.67869053
57DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.67727364
58SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.65328786
59* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.64458618
60NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.62002239
61P300_27058665_Chip-Seq_ZR-75-30cells_Human1.61803172
62SOX2_16153702_ChIP-ChIP_HESCs_Human1.60232453
63EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.57922894
64HIF1A_21447827_ChIP-Seq_MCF-7_Human1.57885046
65THAP11_20581084_ChIP-Seq_MESCs_Mouse1.57643365
66KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.55435062
67TCF3_18692474_ChIP-Seq_MESCs_Mouse1.53995706
68KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.53955361
69KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.53955361
70KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.53955361
71SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.52568082
72FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.51950517
73KDM2B_26808549_Chip-Seq_JURKAT_Human1.51913352
74POU5F1_16153702_ChIP-ChIP_HESCs_Human1.51581666
75PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.50139074
76FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.49518381
77VDR_21846776_ChIP-Seq_THP-1_Human1.49044801
78AR_21909140_ChIP-Seq_LNCAP_Human1.48171882
79FOXP3_21729870_ChIP-Seq_TREG_Human1.47393096
80PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.45601389
81ZNF263_19887448_ChIP-Seq_K562_Human1.45183452
82TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.44739171
83ETS1_20019798_ChIP-Seq_JURKAT_Human1.44243534
84WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.43973589
85DCP1A_22483619_ChIP-Seq_HELA_Human1.43681572
86CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.42954111
87NOTCH1_21737748_ChIP-Seq_TLL_Human1.42901492
88KDM2B_26808549_Chip-Seq_K562_Human1.41357365
89GATA6_25053715_ChIP-Seq_YYC3_Human1.40758084
90TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.39680095
91SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.39295902
92E2F1_18555785_ChIP-Seq_MESCs_Mouse1.37628543
93ELK1_19687146_ChIP-ChIP_HELA_Human1.37496908
94PADI4_21655091_ChIP-ChIP_MCF-7_Human1.36965021
95EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.36447779
96RACK7_27058665_Chip-Seq_MCF-7_Human1.36248229
97ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.35978657
98CREB1_26743006_Chip-Seq_LNCaP_Human1.35799530
99ESR1_15608294_ChIP-ChIP_MCF-7_Human1.34930752
100GABP_17652178_ChIP-ChIP_JURKAT_Human1.34759135
101NANOG_16153702_ChIP-ChIP_HESCs_Human1.34729001
102NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.33932728
103CHD1_26751641_Chip-Seq_LNCaP_Human1.33786810
104NCOR1_26117541_ChIP-Seq_K562_Human1.33606664
105E2F4_17652178_ChIP-ChIP_JURKAT_Human1.33218989
106FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.32573069
107ATF3_27146783_Chip-Seq_COLON_Human1.31307631
108NANOG_21062744_ChIP-ChIP_HESCs_Human1.30876670
109GATA1_26923725_Chip-Seq_HPCs_Mouse1.30077024
110STAT3_1855785_ChIP-Seq_MESCs_Mouse1.27556217
111ISL1_27105846_Chip-Seq_CPCs_Mouse1.26914494
112KDM5A_27292631_Chip-Seq_BREAST_Human1.26071727
113FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.26069029
114PKCTHETA_26484144_Chip-Seq_BREAST_Human1.25931327
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.25055822
116NFIB_24661679_ChIP-Seq_LUNG_Mouse1.24351051
117PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.23902230
118MYC_18940864_ChIP-ChIP_HL60_Human1.23402104
119ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.23184918
120NANOG_18555785_ChIP-Seq_MESCs_Mouse1.23110804
121NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.19973393
122E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19452849
123UTX_26944678_Chip-Seq_JUKART_Human1.18827175
124HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.18622543
125RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.18152332
126RUNX1_27514584_Chip-Seq_MCF-7_Human1.18028864
127LXR_22292898_ChIP-Seq_THP-1_Human1.17207857
128CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.16635911
129FOXO3_23340844_ChIP-Seq_DLD1_Human1.15398890
130HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15393414
131POU5F1_16518401_ChIP-PET_MESCs_Mouse1.14764557
132VDR_23849224_ChIP-Seq_CD4+_Human1.14453112
133YY1_21170310_ChIP-Seq_MESCs_Mouse1.14211338
134CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.13659527
135JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.12887840
136* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.11596963
137CIITA_25753668_ChIP-Seq_RAJI_Human1.11366306
138FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.10551938
139E2F1_21310950_ChIP-Seq_MCF-7_Human1.10538785
140NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.09042237
141* FOXA2_19822575_ChIP-Seq_HepG2_Human1.08938257
142GABP_19822575_ChIP-Seq_HepG2_Human1.05686525
143TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.04077366
144ESR2_21235772_ChIP-Seq_MCF-7_Human1.03265460
145TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.03219649
146SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.01912219
147MAF_26560356_Chip-Seq_TH1_Human0.99706453
148* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.99520513
149SOX2_18555785_ChIP-Seq_MESCs_Mouse0.99071864
150KLF4_18555785_ChIP-Seq_MESCs_Mouse0.98728599
151UBF1/2_26484160_Chip-Seq_HMECs_Human0.97398778
152* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96448085
153EWS_26573619_Chip-Seq_HEK293_Human0.96429751
154ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96289038
155POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96228283
156* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.96166041
157TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.94322497
158UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.93673998
159FUS_26573619_Chip-Seq_HEK293_Human0.93593744
160TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.92964843
161TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.91672615
162HOXB4_20404135_ChIP-ChIP_EML_Mouse0.88422897
163ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.87133520
164CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.85319366
165TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.84475510
166HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human0.83503856

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.06503250
2MP0003693_abnormal_embryo_hatching3.50475192
3MP0002139_abnormal_hepatobiliary_system3.24550864
4MP0010094_abnormal_chromosome_stability3.03925467
5MP0010030_abnormal_orbit_morphology2.81673603
6MP0005076_abnormal_cell_differentiation2.67049092
7MP0006292_abnormal_olfactory_placode2.57128883
8MP0005360_urolithiasis2.53611925
9MP0008877_abnormal_DNA_methylation2.48045777
10MP0009053_abnormal_anal_canal2.47425968
11MP0010352_gastrointestinal_tract_polyps2.40347799
12MP0003718_maternal_effect2.35508739
13MP0008058_abnormal_DNA_repair2.30294821
14MP0000566_synostosis2.16919441
15MP0008932_abnormal_embryonic_tissue2.16548812
16MP0000537_abnormal_urethra_morphology2.13783084
17MP0005365_abnormal_bile_salt2.09891410
18MP0005085_abnormal_gallbladder_physiolo2.08981661
19MP0003136_yellow_coat_color2.05621839
20MP0003252_abnormal_bile_duct2.04521413
21MP0005248_abnormal_Harderian_gland2.03258835
22MP0003890_abnormal_embryonic-extraembry1.97117733
23MP0001346_abnormal_lacrimal_gland1.92436943
24MP0002653_abnormal_ependyma_morphology1.85611220
25MP0003941_abnormal_skin_development1.81829697
26MP0008961_abnormal_basal_metabolism1.81287668
27MP0004264_abnormal_extraembryonic_tissu1.76609771
28MP0004197_abnormal_fetal_growth/weight/1.76018265
29MP0003566_abnormal_cell_adhesion1.73305144
30MP0005380_embryogenesis_phenotype1.66343456
31MP0001672_abnormal_embryogenesis/_devel1.66343456
32MP0010368_abnormal_lymphatic_system1.65388407
33MP0008789_abnormal_olfactory_epithelium1.64996005
34MP0002088_abnormal_embryonic_growth/wei1.63995478
35MP0003300_gastrointestinal_ulcer1.63098427
36MP0003984_embryonic_growth_retardation1.62005099
37MP0003123_paternal_imprinting1.61986872
38MP0009672_abnormal_birth_weight1.60721150
39MP0008007_abnormal_cellular_replicative1.59219076
40MP0002086_abnormal_extraembryonic_tissu1.55170625
41MP0003315_abnormal_perineum_morphology1.55013858
42MP0003119_abnormal_digestive_system1.54982910
43MP0002084_abnormal_developmental_patter1.54820072
44MP0005499_abnormal_olfactory_system1.54382387
45MP0005394_taste/olfaction_phenotype1.54382387
46MP0000428_abnormal_craniofacial_morphol1.51921868
47MP0003567_abnormal_fetal_cardiomyocyte1.50290221
48MP0004185_abnormal_adipocyte_glucose1.49449230
49MP0000049_abnormal_middle_ear1.48685361
50MP0001849_ear_inflammation1.47836792
51MP0010234_abnormal_vibrissa_follicle1.47428788
52MP0001915_intracranial_hemorrhage1.45201054
53MP0005670_abnormal_white_adipose1.44971783
54MP0002009_preneoplasia1.44730226
55MP0002085_abnormal_embryonic_tissue1.41957000
56MP0001293_anophthalmia1.41881128
57MP0001730_embryonic_growth_arrest1.41719635
58MP0009697_abnormal_copulation1.41313056
59MP0009703_decreased_birth_body1.38172345
60MP0000733_abnormal_muscle_development1.38099213
61MP0002210_abnormal_sex_determination1.37615299
62MP0003115_abnormal_respiratory_system1.37395531
63MP0002092_abnormal_eye_morphology1.35502761
64MP0009278_abnormal_bone_marrow1.33959507
65MP0002697_abnormal_eye_size1.32534977
66MP0010329_abnormal_lipoprotein_level1.31902868
67MP0003861_abnormal_nervous_system1.30397830
68MP0001697_abnormal_embryo_size1.28858446
69MP0003111_abnormal_nucleus_morphology1.27040934
70MP0003121_genomic_imprinting1.25910264
71MP0003935_abnormal_craniofacial_develop1.25126738
72MP0005666_abnormal_adipose_tissue1.22475898
73MP0003122_maternal_imprinting1.22372313
74MP0009840_abnormal_foam_cell1.21343408
75MP0001929_abnormal_gametogenesis1.18546045
76MP0005187_abnormal_penis_morphology1.14896169
77MP0000350_abnormal_cell_proliferation1.14691802
78MP0002925_abnormal_cardiovascular_devel1.14468221
79MP0010307_abnormal_tumor_latency1.14116404
80MP0002163_abnormal_gland_morphology1.14075252
81MP0004272_abnormal_basement_membrane1.13574272
82MP0002249_abnormal_larynx_morphology1.10379621
83MP0004233_abnormal_muscle_weight1.09747582
84MP0001145_abnormal_male_reproductive1.08334127
85MP0003937_abnormal_limbs/digits/tail_de1.08246905
86MP0008995_early_reproductive_senescence1.07206352
87MP0000313_abnormal_cell_death1.06659838
88MP0010630_abnormal_cardiac_muscle1.04478301
89MP0000516_abnormal_urinary_system1.04216415
90MP0005367_renal/urinary_system_phenotyp1.04216415
91MP0004957_abnormal_blastocyst_morpholog1.03666913
92MP0008875_abnormal_xenobiotic_pharmacok1.02859009
93MP0002080_prenatal_lethality1.02805024
94MP0002877_abnormal_melanocyte_morpholog1.02212466
95MP0000653_abnormal_sex_gland1.01637171
96MP0000609_abnormal_liver_physiology1.01152706
97MP0003385_abnormal_body_wall1.01083298
98MP0005623_abnormal_meninges_morphology1.00738078
99MP0005023_abnormal_wound_healing0.99250222
100MP0002396_abnormal_hematopoietic_system0.99048838
101MP0000631_abnormal_neuroendocrine_gland0.98997410
102MP0002254_reproductive_system_inflammat0.98358093
103MP0002932_abnormal_joint_morphology0.97956453
104MP0003077_abnormal_cell_cycle0.97789759
105MP0003786_premature_aging0.95279547
106MP0002111_abnormal_tail_morphology0.94522861
107MP0001299_abnormal_eye_distance/0.94410456
108MP0009384_cardiac_valve_regurgitation0.94061086
109MP0000266_abnormal_heart_morphology0.92731212
110MP0000432_abnormal_head_morphology0.91983664
111MP0004808_abnormal_hematopoietic_stem0.91794524
112MP0003938_abnormal_ear_development0.91423029
113MP0003698_abnormal_male_reproductive0.89310532
114MP0001188_hyperpigmentation0.89215186
115MP0005375_adipose_tissue_phenotype0.88570899
116MP0003699_abnormal_female_reproductive0.88532840
117MP0001529_abnormal_vocalization0.85285231
118MP0000534_abnormal_ureter_morphology0.85276741
119MP0001340_abnormal_eyelid_morphology0.84510646
120MP0003942_abnormal_urinary_system0.84361284
121MP0008057_abnormal_DNA_replication0.84085638
122MP0001666_abnormal_nutrient_absorption0.83092604
123MP0000767_abnormal_smooth_muscle0.83046237
124MP0002116_abnormal_craniofacial_bone0.82701171
125MP0002081_perinatal_lethality0.82515124
126MP0000647_abnormal_sebaceous_gland0.82193715
127MP0002938_white_spotting0.81884284
128MP0003283_abnormal_digestive_organ0.81391993
129MP0002161_abnormal_fertility/fecundity0.81362132
130MP0009379_abnormal_foot_pigmentation0.79491149
131MP0004133_heterotaxia0.79304977
132MP0006138_congestive_heart_failure0.78775333
133MP0003943_abnormal_hepatobiliary_system0.77621903
134MP0002128_abnormal_blood_circulation0.77482661
135MP0000579_abnormal_nail_morphology0.77481557
136MP0003806_abnormal_nucleotide_metabolis0.77464250
137MP0001286_abnormal_eye_development0.77384880
138MP0000490_abnormal_crypts_of0.77029505
139MP0000598_abnormal_liver_morphology0.76643386
140MP0003221_abnormal_cardiomyocyte_apopto0.74964687
141MP0003453_abnormal_keratinocyte_physiol0.74389757
142MP0003787_abnormal_imprinting0.72907215
143MP0001614_abnormal_blood_vessel0.71640919
144MP0001119_abnormal_female_reproductive0.71013255
145MP0000778_abnormal_nervous_system0.70880218
146MP0003755_abnormal_palate_morphology0.69995893
147MP0002089_abnormal_postnatal_growth/wei0.69503101
148MP0006054_spinal_hemorrhage0.68514034
149MP0002233_abnormal_nose_morphology0.68409629
150MP0003091_abnormal_cell_migration0.68303688
151MP0008770_decreased_survivor_rate0.67988381

Predicted human phenotypes

RankGene SetZ-score
1Short 4th metacarpal (HP:0010044)3.67832793
2Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.67832793
3Renal duplication (HP:0000075)3.30837311
4Shoulder girdle muscle weakness (HP:0003547)3.26763309
5Hyperacusis (HP:0010780)3.26743027
6Septo-optic dysplasia (HP:0100842)3.26589653
7Chromosomal breakage induced by crosslinking agents (HP:0003221)3.23530897
8Abnormality of the 4th metacarpal (HP:0010012)3.20122368
9Deep venous thrombosis (HP:0002625)3.14578597
10Chromsome breakage (HP:0040012)3.10234354
11Nephroblastoma (Wilms tumor) (HP:0002667)3.09786159
12Pseudobulbar signs (HP:0002200)3.09471312
13Embryonal renal neoplasm (HP:0011794)2.94144915
14Reticulocytopenia (HP:0001896)2.90187544
15Aplasia/Hypoplasia of the sternum (HP:0006714)2.85336865
16Pelvic girdle muscle weakness (HP:0003749)2.76469762
17Renovascular hypertension (HP:0100817)2.73509278
18Abnormality of the septum pellucidum (HP:0007375)2.70592374
19Elfin facies (HP:0004428)2.69263250
20Birth length less than 3rd percentile (HP:0003561)2.64326188
21Abnormality of the labia minora (HP:0012880)2.63222052
22Lymphangioma (HP:0100764)2.60466522
23Ependymoma (HP:0002888)2.58323917
24High anterior hairline (HP:0009890)2.50684983
25Abnormal lung lobation (HP:0002101)2.40798671
26Intrahepatic cholestasis (HP:0001406)2.40572538
27Medulloblastoma (HP:0002885)2.38591225
28Shallow orbits (HP:0000586)2.37023671
29Absent septum pellucidum (HP:0001331)2.35988596
30Urethral obstruction (HP:0000796)2.33966977
31Missing ribs (HP:0000921)2.31683262
32Spastic diplegia (HP:0001264)2.31592796
33Abnormality of monocarboxylic acid metabolism (HP:0010996)2.31150636
34Astrocytoma (HP:0009592)2.29821840
35Abnormality of the astrocytes (HP:0100707)2.29821840
36Cerebral aneurysm (HP:0004944)2.29684007
37Increased nuchal translucency (HP:0010880)2.28690688
38Long eyelashes (HP:0000527)2.28175251
39Macroorchidism (HP:0000053)2.28114591
40Absent radius (HP:0003974)2.25902942
41Broad alveolar ridges (HP:0000187)2.22316157
42Meckel diverticulum (HP:0002245)2.21884356
4311 pairs of ribs (HP:0000878)2.21525267
44Heterotopia (HP:0002282)2.20251244
45Subacute progressive viral hepatitis (HP:0006572)2.20209485
46Colon cancer (HP:0003003)2.18860172
47Abnormality of the hip-girdle musculature (HP:0001445)2.18156954
48Abnormality of the musculature of the pelvis (HP:0001469)2.18156954
49Deviation of the thumb (HP:0009603)2.18036283
50Abnormality of the diencephalon (HP:0010662)2.16246467
51Ectopic kidney (HP:0000086)2.15909659
52Rectal prolapse (HP:0002035)2.15828085
53Absent eyebrow (HP:0002223)2.13542954
54Back pain (HP:0003418)2.12585989
55Abnormality of the ileum (HP:0001549)2.12418245
56Abnormality of the fingertips (HP:0001211)2.11592234
57Partial duplication of thumb phalanx (HP:0009944)2.10629293
58Duplication of thumb phalanx (HP:0009942)2.10409283
59Proximal placement of thumb (HP:0009623)2.08148856
60Trigonocephaly (HP:0000243)2.06759083
61Broad thumb (HP:0011304)2.05586769
62Abdominal situs inversus (HP:0003363)2.05449592
63Abnormality of abdominal situs (HP:0011620)2.05449592
64Esophageal varix (HP:0002040)2.05199347
65Abnormality of chromosome stability (HP:0003220)2.04401429
66Mitral valve prolapse (HP:0001634)2.04316699
67Hypobetalipoproteinemia (HP:0003563)2.04046507
68Rib fusion (HP:0000902)2.03461820
69Aplasia involving forearm bones (HP:0009822)2.02849813
70Absent forearm bone (HP:0003953)2.02849813
71Bilateral microphthalmos (HP:0007633)2.01587344
72Impulsivity (HP:0100710)2.00894951
73Papillary thyroid carcinoma (HP:0002895)1.98310754
74Cortical dysplasia (HP:0002539)1.98293026
75Rimmed vacuoles (HP:0003805)1.97327650
76Depressed nasal tip (HP:0000437)1.97099640
77Aneurysm (HP:0002617)1.96500005
78Skin tags (HP:0010609)1.96033157
79Supernumerary ribs (HP:0005815)1.95916873
80Skull defect (HP:0001362)1.95544113
81Horseshoe kidney (HP:0000085)1.95195071
82Homocystinuria (HP:0002156)1.94723199
83Abnormality of homocysteine metabolism (HP:0010919)1.94723199
84Maternal diabetes (HP:0009800)1.94481855
85Malignant gastrointestinal tract tumors (HP:0006749)1.94290494
86Gastrointestinal carcinoma (HP:0002672)1.94290494
87Capillary hemangiomas (HP:0005306)1.92223701
88Short 5th finger (HP:0009237)1.91678337
89Aplasia/Hypoplasia of the uvula (HP:0010293)1.91422352
90Esophageal atresia (HP:0002032)1.89716547
91Obsessive-compulsive behavior (HP:0000722)1.89367906
92Ulnar bowing (HP:0003031)1.88144399
93Overriding aorta (HP:0002623)1.87869931
94Neoplasm of striated muscle (HP:0009728)1.87486220
95Xanthomatosis (HP:0000991)1.86380245
96Abnormality of the parietal bone (HP:0002696)1.84697309
97Volvulus (HP:0002580)1.84656257
98Premature ovarian failure (HP:0008209)1.84503133
99Atresia of the external auditory canal (HP:0000413)1.83648203
100Syringomyelia (HP:0003396)1.83314117
101Spinal cord lesions (HP:0100561)1.83314117
102Neoplasm of the oral cavity (HP:0100649)1.83075780
103Fibrous tissue neoplasm (HP:0012316)1.82504566
104Fibroma (HP:0010614)1.82314763
105Embryonal neoplasm (HP:0002898)1.82093016
106Progressive muscle weakness (HP:0003323)1.81846544
107Partial duplication of the phalanx of hand (HP:0009999)1.81125716
108Anal stenosis (HP:0002025)1.80435790
109Optic nerve hypoplasia (HP:0000609)1.80139911
110Hepatoblastoma (HP:0002884)1.79363897
111Deep philtrum (HP:0002002)1.79278997
112Abnormality of the lacrimal duct (HP:0011481)1.77721443
113Choanal stenosis (HP:0000452)1.77714130
114Enlarged penis (HP:0000040)1.77247446
115Gonadotropin excess (HP:0000837)1.75003429
116Selective tooth agenesis (HP:0001592)1.74992989
117Abnormality of sulfur amino acid metabolism (HP:0004339)1.74929562
118Acute lymphatic leukemia (HP:0006721)1.74604251
119Abnormality of the distal phalanx of the thumb (HP:0009617)1.73914720
120Coronal craniosynostosis (HP:0004440)1.73568703
121Glossoptosis (HP:0000162)1.73430030
122Abnormality of the preputium (HP:0100587)1.72870723
123Triphalangeal thumb (HP:0001199)1.72740729
124Rhabdomyosarcoma (HP:0002859)1.71906621
125Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.71780058
126Flat cornea (HP:0007720)1.71693272
127Hypolipoproteinemia (HP:0010981)1.71483506
128Abnormality of the salivary glands (HP:0010286)1.71078182
129Concave nail (HP:0001598)1.70475199
130Disproportionate tall stature (HP:0001519)1.69257317
131Protrusio acetabuli (HP:0003179)1.68694534
132Small intestinal stenosis (HP:0012848)1.68418794
133Duodenal stenosis (HP:0100867)1.68418794
134Patellar aplasia (HP:0006443)1.68059868
135Abnormal number of incisors (HP:0011064)1.67593055
136Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67542506
137Broad metatarsal (HP:0001783)1.67507608
138Vertebral fusion (HP:0002948)1.67472874
139Cutis marmorata (HP:0000965)1.67246904
140Spina bifida occulta (HP:0003298)1.66407441
141Hypoalphalipoproteinemia (HP:0003233)1.66385458
142Myelomeningocele (HP:0002475)1.66227498
143Preauricular skin tag (HP:0000384)1.65947368
144Glioma (HP:0009733)1.64968965
145Carpal bone hypoplasia (HP:0001498)1.64744493
146Generalized hypotonia (HP:0001290)1.64578574
147Bifid tongue (HP:0010297)1.64447779
148Deviation of the hallux (HP:0010051)1.64107215
149Macrocytic anemia (HP:0001972)1.63924918
150Stenosis of the external auditory canal (HP:0000402)1.63646600
151Non-midline cleft lip (HP:0100335)1.63627355
152Basal cell carcinoma (HP:0002671)1.63392581
153Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.63367003
154Aplasia/Hypoplasia of the sacrum (HP:0008517)1.63357639
155Persistence of primary teeth (HP:0006335)1.63191092
156Abnormal hair whorl (HP:0010721)1.63078118
157Progressive external ophthalmoplegia (HP:0000590)1.62692082
158Bladder diverticulum (HP:0000015)1.62318079
159Sandal gap (HP:0001852)1.62033774
160Partial agenesis of the corpus callosum (HP:0001338)1.61737432
161Short phalanx of the thumb (HP:0009660)1.61272272
162Hallux valgus (HP:0001822)1.61255294
163Turricephaly (HP:0000262)1.60654593
164Supernumerary bones of the axial skeleton (HP:0009144)1.60315270
165Large earlobe (HP:0009748)1.59910498
166Leiomyosarcoma (HP:0100243)1.59110749
167Uterine leiomyosarcoma (HP:0002891)1.59110749
168Epidermoid cyst (HP:0200040)1.57094453
169Hypoplastic labia majora (HP:0000059)1.55652453
170Facial hemangioma (HP:0000329)1.55624020
171Arnold-Chiari malformation (HP:0002308)1.55259478
172Narrow palate (HP:0000189)1.54819929
173Insomnia (HP:0100785)1.53860803
174Vertebral arch anomaly (HP:0008438)1.53782250
175Biliary tract neoplasm (HP:0100574)1.53590914
176Aortic aneurysm (HP:0004942)1.53361228
177Myocardial infarction (HP:0001658)1.53327475
178Increased mean platelet volume (HP:0011877)1.53009880
179Vertebral clefting (HP:0008428)1.52526661
180Hemivertebrae (HP:0002937)1.50007722

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.53518735
2TRIB33.70940691
3LATS13.69821736
4MAP3K103.67553972
5PKN23.10873919
6SRPK13.07356325
7BUB12.79893793
8EEF2K2.71765995
9SIK12.44685996
10RIPK12.22019396
11PLK42.21021316
12PTK62.13749045
13PASK2.12416942
14ERN11.99430342
15CDK191.97921099
16CAMK1D1.97699592
17TAF11.93766481
18PNCK1.88487398
19ICK1.85208165
20PDGFRA1.80178211
21BRD41.80072215
22MTOR1.67710542
23LATS21.67043153
24STK31.63337494
25CAMK1G1.61039235
26NEK21.60285787
27ZAK1.58293132
28TTN1.54398547
29EPHA21.46481292
30BRSK21.45707933
31PAK41.43185129
32CDK41.35264078
33PLK11.35138779
34FGFR41.32516107
35MAP3K91.32187527
36ALK1.31672475
37CDK61.29354257
38CDC71.28750018
39WEE11.25654844
40PLK31.19289144
41PBK1.16460205
42MKNK21.11132410
43CDK71.07457426
44STK101.06436572
45BMX1.03680196
46TRIM281.02731635
47FGFR11.02380524
48MKNK11.01643886
49TYRO31.01625783
50TGFBR10.98926004
51RPS6KB20.97007081
52TNIK0.96359658
53SMG10.95966248
54BRSK10.93109808
55MAP3K70.92295079
56STK240.91537469
57PTK20.90733049
58EPHB20.89960163
59PAK20.89096345
60CDK90.86804554
61FLT30.85561748
62TTK0.85543273
63ERBB20.83512003
64YES10.83503435
65LRRK20.83065440
66FGFR20.82869228
67MAP3K40.82536767
68EPHA30.82483923
69TGFBR20.82238489
70AURKA0.81570437
71PDGFRB0.78865692
72VRK20.78119349
73VRK10.77453520
74CDK80.77408850
75RPS6KA40.76979248
76SIK20.76719680
77DMPK0.76505081
78CHEK10.74928005
79MAP3K80.74524110
80CLK10.71847548
81FGFR30.71843163
82TAOK10.71664779
83DYRK20.68839469
84STK40.68596158
85PIM10.68211851
86SCYL20.67704573
87DDR20.67419627
88CASK0.66600704
89NEK10.66201328
90TSSK60.66090397
91PRKD30.65673189
92CDK30.65661127
93TIE10.64213237
94PRPF4B0.63596579
95CDK20.61260965
96ERBB40.61051747
97GRK60.59580534
98BRAF0.57988517
99SGK30.57591787
100EPHB10.56148204
101CHUK0.55584076
102NME10.54925113
103AKT20.51441074
104MARK20.51403575
105ATM0.51303166
106KSR20.50837025
107STK38L0.48678698
108CSNK1D0.48059267
109PRKDC0.47786705
110MAPK110.47424499
111GSK3A0.46924773
112RPS6KA20.46602877
113ATR0.46185289
114CSNK2A20.46073379
115RPS6KA10.45060227
116EIF2AK20.45007515
117CAMKK10.43880913
118MAP2K30.43416509
119CHEK20.43332779
120CSNK1E0.42905027
121PRKAA10.42712127
122MAP2K70.42474242
123DYRK30.41891857
124MAPK10.41713240
125RAF10.41641913
126NUAK10.40584856
127RET0.40301110
128CSNK1G10.39974533
129AKT10.38756730
130IRAK20.38316119
131MAPK140.38221676
132PRKAA20.38148997
133CDK10.37761102
134MELK0.37386737
135AURKB0.37309480
136INSRR0.37303487
137DYRK1B0.36203754
138RPS6KB10.34748073
139HIPK20.34621282
140MAPK100.34302057
141BCR0.34032641
142CDK11A0.33912083
143RPS6KC10.33397323
144RPS6KL10.33397323
145KSR10.32818377
146TAOK30.32805922
147JAK20.32553291
148GSK3B0.32235383

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.08139924
2Mismatch repair_Homo sapiens_hsa034303.60857622
3Spliceosome_Homo sapiens_hsa030403.31291894
4Nitrogen metabolism_Homo sapiens_hsa009103.08154072
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.81585079
6Base excision repair_Homo sapiens_hsa034102.72168099
7Non-homologous end-joining_Homo sapiens_hsa034502.62401678
8Lysine degradation_Homo sapiens_hsa003102.61985309
9Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.61387108
10Ribosome_Homo sapiens_hsa030102.45970248
11Basal transcription factors_Homo sapiens_hsa030222.39684347
12Nucleotide excision repair_Homo sapiens_hsa034202.24540717
13Arginine biosynthesis_Homo sapiens_hsa002202.22865206
14RNA polymerase_Homo sapiens_hsa030202.20161914
15Homologous recombination_Homo sapiens_hsa034402.06887379
16Primary bile acid biosynthesis_Homo sapiens_hsa001201.98460605
17RNA degradation_Homo sapiens_hsa030181.95724756
18Fanconi anemia pathway_Homo sapiens_hsa034601.93303614
19Selenocompound metabolism_Homo sapiens_hsa004501.93104180
20Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.90169326
21Basal cell carcinoma_Homo sapiens_hsa052171.84787535
22One carbon pool by folate_Homo sapiens_hsa006701.72049926
23Caffeine metabolism_Homo sapiens_hsa002321.71951197
24Complement and coagulation cascades_Homo sapiens_hsa046101.53269035
25Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.50304867
26mTOR signaling pathway_Homo sapiens_hsa041501.50288579
27MicroRNAs in cancer_Homo sapiens_hsa052061.43624928
28Adherens junction_Homo sapiens_hsa045201.43282048
29Hippo signaling pathway_Homo sapiens_hsa043901.40520914
30Chronic myeloid leukemia_Homo sapiens_hsa052201.40160107
31Tryptophan metabolism_Homo sapiens_hsa003801.40121167
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.38944980
33Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.36977188
34Fatty acid degradation_Homo sapiens_hsa000711.36724762
35Notch signaling pathway_Homo sapiens_hsa043301.35426255
36Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.32761314
37Insulin resistance_Homo sapiens_hsa049311.30852575
38Biosynthesis of amino acids_Homo sapiens_hsa012301.29175440
39Small cell lung cancer_Homo sapiens_hsa052221.25836462
40Oocyte meiosis_Homo sapiens_hsa041141.22827197
41Bile secretion_Homo sapiens_hsa049761.22660252
42Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.22639910
43p53 signaling pathway_Homo sapiens_hsa041151.22280668
44Hedgehog signaling pathway_Homo sapiens_hsa043401.21737936
45Steroid biosynthesis_Homo sapiens_hsa001001.16292090
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.15534706
47PPAR signaling pathway_Homo sapiens_hsa033201.15154123
48Pyrimidine metabolism_Homo sapiens_hsa002401.14283737
49Central carbon metabolism in cancer_Homo sapiens_hsa052301.14217383
50Proteoglycans in cancer_Homo sapiens_hsa052051.11601945
51Fatty acid metabolism_Homo sapiens_hsa012121.11020223
52Fat digestion and absorption_Homo sapiens_hsa049751.06214148
53mRNA surveillance pathway_Homo sapiens_hsa030151.01944417
54Endometrial cancer_Homo sapiens_hsa052131.01870374
55Cysteine and methionine metabolism_Homo sapiens_hsa002700.96525659
56Thyroid hormone signaling pathway_Homo sapiens_hsa049190.95428860
57Drug metabolism - other enzymes_Homo sapiens_hsa009830.92519149
58AMPK signaling pathway_Homo sapiens_hsa041520.90410185
59Bladder cancer_Homo sapiens_hsa052190.88698719
60RNA transport_Homo sapiens_hsa030130.88232913
61Longevity regulating pathway - mammal_Homo sapiens_hsa042110.86770071
62Dorso-ventral axis formation_Homo sapiens_hsa043200.86375009
63Colorectal cancer_Homo sapiens_hsa052100.86333560
64Insulin signaling pathway_Homo sapiens_hsa049100.86232296
65Non-small cell lung cancer_Homo sapiens_hsa052230.85803530
66Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.85649487
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85618024
68Epstein-Barr virus infection_Homo sapiens_hsa051690.85530092
69Focal adhesion_Homo sapiens_hsa045100.85241054
70Staphylococcus aureus infection_Homo sapiens_hsa051500.83967459
71Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.79238967
72Acute myeloid leukemia_Homo sapiens_hsa052210.78688480
73Glucagon signaling pathway_Homo sapiens_hsa049220.77046020
74Carbon metabolism_Homo sapiens_hsa012000.77002245
75TGF-beta signaling pathway_Homo sapiens_hsa043500.73821153
76Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.73691186
77Starch and sucrose metabolism_Homo sapiens_hsa005000.73544883
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73088249
79ErbB signaling pathway_Homo sapiens_hsa040120.72854246
80Fatty acid biosynthesis_Homo sapiens_hsa000610.72021003
81HTLV-I infection_Homo sapiens_hsa051660.71917984
82Purine metabolism_Homo sapiens_hsa002300.71744355
83Pancreatic cancer_Homo sapiens_hsa052120.71397449
84ABC transporters_Homo sapiens_hsa020100.71194751
85Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.70544251
86ECM-receptor interaction_Homo sapiens_hsa045120.70516552
87Maturity onset diabetes of the young_Homo sapiens_hsa049500.69352833
88Adipocytokine signaling pathway_Homo sapiens_hsa049200.69113301
89Prostate cancer_Homo sapiens_hsa052150.68247246
90Type II diabetes mellitus_Homo sapiens_hsa049300.67343084
91Cell cycle_Homo sapiens_hsa041100.67086059
92Viral myocarditis_Homo sapiens_hsa054160.66512758
93Pathways in cancer_Homo sapiens_hsa052000.65519707
94Transcriptional misregulation in cancer_Homo sapiens_hsa052020.65001061
95Herpes simplex infection_Homo sapiens_hsa051680.64041581
96Alcoholism_Homo sapiens_hsa050340.63039943
97Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62423103
98Tight junction_Homo sapiens_hsa045300.61278678
99Wnt signaling pathway_Homo sapiens_hsa043100.60796206
100Systemic lupus erythematosus_Homo sapiens_hsa053220.59178438
101Renal cell carcinoma_Homo sapiens_hsa052110.58889411
102Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.58693117
103Retinol metabolism_Homo sapiens_hsa008300.57906377
104Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.57421673
105Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.57041120
106Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.56809602
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.55918590
108Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55282189
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.54286779
110Melanoma_Homo sapiens_hsa052180.52578781
111FoxO signaling pathway_Homo sapiens_hsa040680.51458000
112Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.51232830
113Viral carcinogenesis_Homo sapiens_hsa052030.50819143
114Cyanoamino acid metabolism_Homo sapiens_hsa004600.50704260
115Glioma_Homo sapiens_hsa052140.50625299
116Vitamin digestion and absorption_Homo sapiens_hsa049770.49323928
117Gap junction_Homo sapiens_hsa045400.47312772
118Thyroid cancer_Homo sapiens_hsa052160.46440520
119Proteasome_Homo sapiens_hsa030500.46270308
120Amoebiasis_Homo sapiens_hsa051460.45886084
121Prolactin signaling pathway_Homo sapiens_hsa049170.44941708
122Propanoate metabolism_Homo sapiens_hsa006400.44120304
123Pentose and glucuronate interconversions_Homo sapiens_hsa000400.43261602
124Hepatitis B_Homo sapiens_hsa051610.43188084
125Pentose phosphate pathway_Homo sapiens_hsa000300.43175623
126Steroid hormone biosynthesis_Homo sapiens_hsa001400.42727507
127Chemical carcinogenesis_Homo sapiens_hsa052040.42452685
128AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.42118319
129beta-Alanine metabolism_Homo sapiens_hsa004100.41644332
130Inositol phosphate metabolism_Homo sapiens_hsa005620.41003135
131Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.39740963
132Choline metabolism in cancer_Homo sapiens_hsa052310.39180757
133Axon guidance_Homo sapiens_hsa043600.38099191
134Sulfur relay system_Homo sapiens_hsa041220.36981437
135Melanogenesis_Homo sapiens_hsa049160.35891935
136Circadian rhythm_Homo sapiens_hsa047100.32152645
137Huntingtons disease_Homo sapiens_hsa050160.28816918
138Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.25345559
139Apoptosis_Homo sapiens_hsa042100.24559066
140Folate biosynthesis_Homo sapiens_hsa007900.23357325
141Long-term depression_Homo sapiens_hsa047300.23146031
142Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22838932
143Vitamin B6 metabolism_Homo sapiens_hsa007500.19928608

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