ZBTB40

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)4.44016181
2positive regulation of gamma-delta T cell activation (GO:0046645)4.31461723
3mannose metabolic process (GO:0006013)4.08664679
4nuclear pore organization (GO:0006999)4.02324782
5regulation of gamma-delta T cell differentiation (GO:0045586)3.88336868
6daunorubicin metabolic process (GO:0044597)3.81611776
7polyketide metabolic process (GO:0030638)3.81611776
8doxorubicin metabolic process (GO:0044598)3.81611776
9NIK/NF-kappaB signaling (GO:0038061)3.80458846
10histone H3-K4 trimethylation (GO:0080182)3.79262565
11negative regulation of histone methylation (GO:0031061)3.70621433
12regulation of gamma-delta T cell activation (GO:0046643)3.64935627
13antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.48102873
14antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.48102873
15IMP biosynthetic process (GO:0006188)3.47112318
16pore complex assembly (GO:0046931)3.43947435
17regulation of B cell receptor signaling pathway (GO:0050855)3.42087270
18B cell receptor signaling pathway (GO:0050853)3.38419818
19protein localization to kinetochore (GO:0034501)3.36405149
20positive thymic T cell selection (GO:0045059)3.34348083
21positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.32988889
22phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.22535994
23folic acid-containing compound biosynthetic process (GO:0009396)3.21210284
24positive regulation of granulocyte differentiation (GO:0030854)3.20782015
25antigen processing and presentation of endogenous antigen (GO:0019883)3.18488947
26mitotic nuclear envelope disassembly (GO:0007077)3.15631792
27response to muramyl dipeptide (GO:0032495)3.15025836
28regulation of histone H3-K9 methylation (GO:0051570)3.10552275
29positive regulation of histone deacetylation (GO:0031065)3.09221040
30positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.08620948
31regulation of NFAT protein import into nucleus (GO:0051532)3.08238855
32positive regulation of B cell differentiation (GO:0045579)3.05693975
33positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.05347608
34monoubiquitinated protein deubiquitination (GO:0035520)3.01051895
35protein localization to chromosome, centromeric region (GO:0071459)2.99965940
36cytoplasmic mRNA processing body assembly (GO:0033962)2.98165640
37RNA stabilization (GO:0043489)2.98134881
38mRNA stabilization (GO:0048255)2.98134881
39response to interleukin-15 (GO:0070672)2.93941285
40pre-miRNA processing (GO:0031054)2.92780030
41membrane disassembly (GO:0030397)2.91123559
42nuclear envelope disassembly (GO:0051081)2.91123559
43germinal center formation (GO:0002467)2.89696765
44peptidyl-lysine trimethylation (GO:0018023)2.89631076
45response to laminar fluid shear stress (GO:0034616)2.88010297
46embryonic process involved in female pregnancy (GO:0060136)2.85448630
47cellular extravasation (GO:0045123)2.83075350
48regulation of spindle organization (GO:0090224)2.82593362
49positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.79434163
50regulation of RNA export from nucleus (GO:0046831)2.77427611
51regulation of ARF protein signal transduction (GO:0032012)2.77194161
52regulation of translational termination (GO:0006449)2.76640754
53mitotic chromosome condensation (GO:0007076)2.75814232
54positive T cell selection (GO:0043368)2.75381544
55mitotic sister chromatid cohesion (GO:0007064)2.75079347
56regulation of interleukin-12 biosynthetic process (GO:0045075)2.74816819
57antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.71353056
58leukocyte aggregation (GO:0070486)2.71297491
59regulation of granulocyte differentiation (GO:0030852)2.71098237
60IMP metabolic process (GO:0046040)2.71050783
61histone lysine methylation (GO:0034968)2.70026885
62tetrahydrofolate metabolic process (GO:0046653)2.69014011
63heterochromatin organization (GO:0070828)2.68405762
64negative T cell selection (GO:0043383)2.68120670
65activated T cell proliferation (GO:0050798)2.67917488
66negative thymic T cell selection (GO:0045060)2.67678155
67histone H4-K16 acetylation (GO:0043984)2.65138226
68modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.64866669
69positive regulation by organism of defense response of other organism involved in symbiotic interact2.64866669
70modulation by symbiont of host immune response (GO:0052553)2.64866669
71positive regulation by symbiont of host defense response (GO:0052509)2.64866669
72modulation by symbiont of host defense response (GO:0052031)2.64866669
73modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.64866669
74negative regulation of T cell mediated immunity (GO:0002710)2.64845280
75regulation of translational fidelity (GO:0006450)2.62684253
76regulation of histone methylation (GO:0031060)2.60858637
77regulation of type I interferon-mediated signaling pathway (GO:0060338)2.60637434
78negative regulation of cell killing (GO:0031342)2.60277191
79negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.60277191
80histone H4 deacetylation (GO:0070933)2.60274740
81regulation of ARF GTPase activity (GO:0032312)2.60212419
82macroautophagy (GO:0016236)2.59487588
83thymic T cell selection (GO:0045061)2.59165022
84regulation of chromatin binding (GO:0035561)2.59054623
85histone H3-K36 demethylation (GO:0070544)2.58753576
86T cell migration (GO:0072678)2.58115316
87sister chromatid segregation (GO:0000819)2.57975473
88DNA duplex unwinding (GO:0032508)2.57800923
89DNA geometric change (GO:0032392)2.55677040
90spliceosomal tri-snRNP complex assembly (GO:0000244)2.55581421
91histone H3-K9 demethylation (GO:0033169)2.54519370
92antigen processing and presentation via MHC class Ib (GO:0002475)2.54445846
93T cell homeostasis (GO:0043029)2.53936355
94regulation of histone H3-K4 methylation (GO:0051569)2.53606185
95B cell homeostasis (GO:0001782)2.53447115
96mitotic sister chromatid segregation (GO:0000070)2.49989959
97negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.49705065
98tolerance induction (GO:0002507)2.49543691
99definitive hemopoiesis (GO:0060216)2.49027879
100T cell selection (GO:0045058)2.48243802
101regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.46937402
102regulation of mitotic spindle organization (GO:0060236)2.44882674
103histone lysine demethylation (GO:0070076)2.43715150
104positive regulation of Rap GTPase activity (GO:0032854)2.43635041
105peptidyl-lysine methylation (GO:0018022)2.43285974
106peptidyl-threonine phosphorylation (GO:0018107)2.42983954
107cellular response to ethanol (GO:0071361)2.41036490
108chromatin assembly (GO:0031497)2.40905989
109histone mRNA catabolic process (GO:0071044)2.40439805
110regulation of T cell tolerance induction (GO:0002664)2.40018091
111histone demethylation (GO:0016577)2.39960726
112histone deubiquitination (GO:0016578)2.39930665
113negative regulation of lymphocyte mediated immunity (GO:0002707)2.39739564
114negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.39735449
115NLS-bearing protein import into nucleus (GO:0006607)2.38828733
116dosage compensation (GO:0007549)2.38606388
117histone H3-K9 modification (GO:0061647)2.37494956
118histone H3-K4 methylation (GO:0051568)2.35956604
119histone H3-K9 methylation (GO:0051567)2.35886021
120nuclear envelope organization (GO:0006998)2.35816546
121negative regulation of myotube differentiation (GO:0010832)2.35213695
122snRNA metabolic process (GO:0016073)2.35172160
123protein dealkylation (GO:0008214)2.33670532
124protein demethylation (GO:0006482)2.33670532
125response to UV-C (GO:0010225)2.32998406
126regulation of glucokinase activity (GO:0033131)2.32336379
127regulation of hexokinase activity (GO:1903299)2.32336379
128snRNA processing (GO:0016180)2.32228391
129regulation of nucleobase-containing compound transport (GO:0032239)2.31530184
130necrotic cell death (GO:0070265)2.31158467
131positive regulation of protein deacetylation (GO:0090312)2.30348850
132gene silencing (GO:0016458)2.29901310
133positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.29525991
134positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.29525991
135positive regulation of mitotic sister chromatid separation (GO:1901970)2.29525991
136gene silencing by RNA (GO:0031047)2.29520705
137JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.29365966
138negative regulation of granulocyte differentiation (GO:0030853)2.29288498
139aminoglycoside antibiotic metabolic process (GO:0030647)2.29262095
140regulation of B cell differentiation (GO:0045577)2.28202311
141activation of JUN kinase activity (GO:0007257)2.27825551
142regulation of histone H3-K27 methylation (GO:0061085)2.27531485
143natural killer cell differentiation (GO:0001779)2.27353941
144regulation of mRNA stability (GO:0043488)2.27206415
145hepatocyte apoptotic process (GO:0097284)2.27190767
146negative regulation of erythrocyte differentiation (GO:0045647)2.26971337
147detection of other organism (GO:0098543)2.26934547
148negative regulation of cell size (GO:0045792)2.26350863
149valine metabolic process (GO:0006573)2.26061871
150regulation of necroptotic process (GO:0060544)2.25603454
151macrophage activation involved in immune response (GO:0002281)2.25566571
152interferon-gamma production (GO:0032609)2.24963908
153folic acid metabolic process (GO:0046655)2.24142228
154positive regulation of DNA-templated transcription, initiation (GO:2000144)2.23467180
155peptidyl-lysine dimethylation (GO:0018027)2.23253210

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.40592413
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.03909048
3EGR1_19374776_ChIP-ChIP_THP-1_Human3.64815053
4MYC_22102868_ChIP-Seq_BL_Human3.15860819
5E2F4_17652178_ChIP-ChIP_JURKAT_Human2.58300163
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.50646639
7VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.49758778
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.47773445
9KDM2B_26808549_Chip-Seq_SUP-B15_Human2.46945636
10STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.43564036
11CIITA_25753668_ChIP-Seq_RAJI_Human2.35826232
12GATA1_22025678_ChIP-Seq_K562_Human2.07197860
13VDR_21846776_ChIP-Seq_THP-1_Human2.01221091
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.98154190
15ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.86924749
16TCF7_22412390_ChIP-Seq_EML_Mouse1.82359988
17* KDM2B_26808549_Chip-Seq_JURKAT_Human1.81540670
18ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.78335037
19MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.76158836
20KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.75958595
21STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.74152547
22MAF_26560356_Chip-Seq_TH1_Human1.73759069
23E2F1_21310950_ChIP-Seq_MCF-7_Human1.72913645
24FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.72278211
25* MYB_26560356_Chip-Seq_TH1_Human1.69214609
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.68717989
27IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.68092601
28MYC_18555785_ChIP-Seq_MESCs_Mouse1.65504062
29SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.64112611
30* UTX_26944678_Chip-Seq_JUKART_Human1.63660702
31* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.62167224
32GATA1_19941826_ChIP-Seq_K562_Human1.60002074
33EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.59063866
34FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.58334483
35MYB_26560356_Chip-Seq_TH2_Human1.57364792
36NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.56033814
37NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.55706600
38BRD4_27068464_Chip-Seq_AML-cells_Mouse1.54130491
39PPARA_22158963_ChIP-Seq_LIVER_Mouse1.53804544
40MYB_21317192_ChIP-Seq_ERMYB_Mouse1.53508618
41BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.51237779
42TP63_19390658_ChIP-ChIP_HaCaT_Human1.49695938
43SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.48483853
44* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.47260290
45SCL_19346495_ChIP-Seq_HPC-7_Human1.45991059
46* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.42992125
47IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.42751737
48EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.42378912
49* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.41982476
50STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.39486205
51TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38873939
52KDM5A_27292631_Chip-Seq_BREAST_Human1.38548519
53IRF8_21731497_ChIP-ChIP_J774_Mouse1.36864350
54GATA1_19941827_ChIP-Seq_MEL_Mouse1.36808074
55MYC_19079543_ChIP-ChIP_MESCs_Mouse1.36290201
56E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.35728942
57* KDM2B_26808549_Chip-Seq_K562_Human1.34129125
58SMAD_19615063_ChIP-ChIP_OVARY_Human1.33715245
59STAT6_21828071_ChIP-Seq_BEAS2B_Human1.33398567
60GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.32689361
61* RXR_22158963_ChIP-Seq_LIVER_Mouse1.32337573
62* KDM2B_26808549_Chip-Seq_DND41_Human1.32035893
63RUNX1_22412390_ChIP-Seq_EML_Mouse1.29277301
64TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.28674718
65LXR_22292898_ChIP-Seq_THP-1_Human1.28415332
66GATA2_19941826_ChIP-Seq_K562_Human1.28396720
67ESR1_20079471_ChIP-ChIP_T-47D_Human1.28283520
68THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.28103229
69* RACK7_27058665_Chip-Seq_MCF-7_Human1.27664761
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.27314404
71SPI1_23547873_ChIP-Seq_NB4_Human1.26885238
72IRF8_27001747_Chip-Seq_BMDM_Mouse1.26762396
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.24463625
74SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.23187518
75TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.22931786
76AR_21909140_ChIP-Seq_LNCAP_Human1.21746181
77* NCOR1_26117541_ChIP-Seq_K562_Human1.20914836
78CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.20180361
79* TFEB_21752829_ChIP-Seq_HELA_Human1.18811278
80* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.18600033
81NOTCH1_21737748_ChIP-Seq_TLL_Human1.18490272
82* RUNX1_27514584_Chip-Seq_MCF-7_Human1.18326475
83RUNX_20019798_ChIP-Seq_JUKART_Human1.15294654
84* MAF_26560356_Chip-Seq_TH2_Human1.13354288
85VDR_24763502_ChIP-Seq_THP-1_Human1.13090974
86* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13051379
87CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.12912973
88LXR_22158963_ChIP-Seq_LIVER_Mouse1.12548062
89ZFP281_27345836_Chip-Seq_ESCs_Mouse1.12418992
90* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.12143559
91NELFA_20434984_ChIP-Seq_ESCs_Mouse1.12057750
92Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.10646362
93* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.10323576
94* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.10079678
95RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.09402904
96STAT4_19710469_ChIP-ChIP_TH1__Mouse1.07680176
97GATA2_22383799_ChIP-Seq_G1ME_Mouse1.06533854
98STAT3_1855785_ChIP-Seq_MESCs_Mouse1.06113086
99SPI1_23127762_ChIP-Seq_K562_Human1.04251577
100* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.03904228
101FOXO3_23340844_ChIP-Seq_DLD1_Human1.03850924
102CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.03003797
103CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.02543257
104* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.01778044
105VDR_24787735_ChIP-Seq_THP-1_Human1.01774236
106CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.01765944
107MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.01596126
108* FOXP3_21729870_ChIP-Seq_TREG_Human1.00677167
109GATA1_22383799_ChIP-Seq_G1ME_Mouse1.00114094
110DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.99058595
111RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.98233221
112ERG_20887958_ChIP-Seq_HPC-7_Mouse0.98171828
113GATA3_27048872_Chip-Seq_THYMUS_Human0.98117075
114GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98064512
115EGR1_23403033_ChIP-Seq_LIVER_Mouse0.97428926
116NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.96968097
117* FOXA2_19822575_ChIP-Seq_HepG2_Human0.96538545
118* GATA6_25053715_ChIP-Seq_YYC3_Human0.96393204
119FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.95661118
120TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95307920
121* VDR_23849224_ChIP-Seq_CD4+_Human0.95065757
122CTCF_27219007_Chip-Seq_ERYTHROID_Human0.93190012
123FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.92676274
124CHD1_26751641_Chip-Seq_LNCaP_Human0.92284137
125MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.92275510
126MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.92230523
127PKCTHETA_26484144_Chip-Seq_BREAST_Human0.92168922
128* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.91975565
129SOX9_24532713_ChIP-Seq_HFSC_Mouse0.91667497
130PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.91266102
131CTNNB1_20460455_ChIP-Seq_HCT116_Human0.89554259
132ELK3_25401928_ChIP-Seq_HUVEC_Human0.89223995
133GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.88478689
134RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88213360
135E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.88126990
136PU_27001747_Chip-Seq_BMDM_Mouse0.87435913
137NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.87257592

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002009_preneoplasia3.10691611
2MP0008057_abnormal_DNA_replication2.85681283
3MP0005451_abnormal_body_composition2.78482601
4MP0003111_abnormal_nucleus_morphology2.65417826
5MP0010352_gastrointestinal_tract_polyps2.65120116
6MP0003693_abnormal_embryo_hatching2.42903942
7MP0010307_abnormal_tumor_latency2.31059246
8MP0005076_abnormal_cell_differentiation2.28562032
9MP0001835_abnormal_antigen_presentation2.23025861
10MP0002396_abnormal_hematopoietic_system2.19525238
11MP0004381_abnormal_hair_follicle2.16197235
12MP0003763_abnormal_thymus_physiology2.08545796
13MP0010094_abnormal_chromosome_stability2.05635954
14MP0000569_abnormal_digit_pigmentation2.01785849
15MP0000685_abnormal_immune_system2.01194672
16MP0003077_abnormal_cell_cycle2.00783149
17MP0003303_peritoneal_inflammation1.95631711
18MP0003252_abnormal_bile_duct1.88261315
19MP0005365_abnormal_bile_salt1.87721182
20MP0001800_abnormal_humoral_immune1.84253583
21MP0004808_abnormal_hematopoietic_stem1.75881322
22MP0001790_abnormal_immune_system1.74711328
23MP0005387_immune_system_phenotype1.74711328
24MP0008007_abnormal_cellular_replicative1.70261512
25MP0002398_abnormal_bone_marrow1.70226946
26MP0005360_urolithiasis1.67710186
27MP0003300_gastrointestinal_ulcer1.67424258
28MP0002138_abnormal_hepatobiliary_system1.63316854
29MP0005058_abnormal_lysosome_morphology1.59408595
30MP0003436_decreased_susceptibility_to1.56694952
31MP0008260_abnormal_autophagy1.52719130
32MP0002452_abnormal_antigen_presenting1.49330731
33MP0005409_darkened_coat_color1.48069490
34MP0000703_abnormal_thymus_morphology1.46054658
35MP0000689_abnormal_spleen_morphology1.44701565
36MP0002723_abnormal_immune_serum1.44289313
37MP0002722_abnormal_immune_system1.43979157
38MP0009278_abnormal_bone_marrow1.43718161
39MP0002928_abnormal_bile_duct1.42612281
40MP0003566_abnormal_cell_adhesion1.42459178
41MP0002166_altered_tumor_susceptibility1.39907194
42MP0005671_abnormal_response_to1.39413808
43MP0004957_abnormal_blastocyst_morpholog1.38882357
44MP0003705_abnormal_hypodermis_morpholog1.38507758
45MP0009840_abnormal_foam_cell1.37899732
46MP0000716_abnormal_immune_system1.37705278
47MP0004264_abnormal_extraembryonic_tissu1.37395461
48MP0008961_abnormal_basal_metabolism1.37186118
49MP0002420_abnormal_adaptive_immunity1.35242474
50MP0001819_abnormal_immune_cell1.34411122
51MP0003984_embryonic_growth_retardation1.31916167
52MP0005464_abnormal_platelet_physiology1.31655322
53MP0001730_embryonic_growth_arrest1.31151674
54MP0002877_abnormal_melanocyte_morpholog1.31035824
55MP0005310_abnormal_salivary_gland1.30233643
56MP0001672_abnormal_embryogenesis/_devel1.30182184
57MP0005380_embryogenesis_phenotype1.30182184
58MP0000350_abnormal_cell_proliferation1.30101750
59MP0004185_abnormal_adipocyte_glucose1.29561041
60MP0002088_abnormal_embryonic_growth/wei1.29017080
61MP0010234_abnormal_vibrissa_follicle1.28964410
62MP0004947_skin_inflammation1.28432279
63MP0001545_abnormal_hematopoietic_system1.27374517
64MP0005397_hematopoietic_system_phenotyp1.27374517
65MP0005670_abnormal_white_adipose1.26925708
66MP0005000_abnormal_immune_tolerance1.26191792
67MP0003828_pulmonary_edema1.26015639
68MP0000609_abnormal_liver_physiology1.25667565
69MP0002429_abnormal_blood_cell1.25262636
70MP0001873_stomach_inflammation1.24173935
71MP0008058_abnormal_DNA_repair1.22944631
72MP0000015_abnormal_ear_pigmentation1.20769139
73MP0003191_abnormal_cellular_cholesterol1.20083229
74MP0001851_eye_inflammation1.19939189
75MP0005025_abnormal_response_to1.19238758
76MP0003045_fibrosis1.19040600
77MP0005085_abnormal_gallbladder_physiolo1.19032755
78MP0002086_abnormal_extraembryonic_tissu1.18559013
79MP0003724_increased_susceptibility_to1.17948287
80MP0002405_respiratory_system_inflammati1.16615363
81MP0010155_abnormal_intestine_physiology1.16587851
82MP0002419_abnormal_innate_immunity1.13784708
83MP0003453_abnormal_keratinocyte_physiol1.12436303
84MP0002139_abnormal_hepatobiliary_system1.11200546
85MP0003656_abnormal_erythrocyte_physiolo1.11017621
86MP0000371_diluted_coat_color1.09172018
87MP0002019_abnormal_tumor_incidence1.06294713
88MP0001845_abnormal_inflammatory_respons1.05681293
89MP0009115_abnormal_fat_cell1.05581423
90MP0002006_tumorigenesis1.03651440
91MP0002998_abnormal_bone_remodeling1.02882215
92MP0001533_abnormal_skeleton_physiology1.02285225
93MP0001915_intracranial_hemorrhage1.02271456
94MP0009333_abnormal_splenocyte_physiolog1.02111983
95MP0001348_abnormal_lacrimal_gland1.01711105
96MP0004233_abnormal_muscle_weight0.99343781
97MP0005075_abnormal_melanosome_morpholog0.98847745
98MP0000490_abnormal_crypts_of0.97053114
99MP0000313_abnormal_cell_death0.97030659
100MP0000465_gastrointestinal_hemorrhage0.96318002
101MP0003183_abnormal_peptide_metabolism0.94297626
102MP0000733_abnormal_muscle_development0.94096634
103MP0002080_prenatal_lethality0.93850428
104MP0004197_abnormal_fetal_growth/weight/0.92542879
105MP0005023_abnormal_wound_healing0.90508557
106MP0000858_altered_metastatic_potential0.89548233
107MP0003786_premature_aging0.88399955
108MP0005666_abnormal_adipose_tissue0.87488123
109MP0005220_abnormal_exocrine_pancreas0.87040612
110MP0001697_abnormal_embryo_size0.86903616
111MP0000598_abnormal_liver_morphology0.86789737
112MP0003866_abnormal_defecation0.86229179
113MP0002933_joint_inflammation0.84825082
114MP0001853_heart_inflammation0.84408672
115MP0005621_abnormal_cell_physiology0.82487916
116MP0001661_extended_life_span0.82144461
117MP0009785_altered_susceptibility_to0.81352163
118MP0002254_reproductive_system_inflammat0.77890745
119MP0003890_abnormal_embryonic-extraembry0.76663554
120MP0008469_abnormal_protein_level0.76451308
121MP0003172_abnormal_lysosome_physiology0.74932287
122MP0002693_abnormal_pancreas_physiology0.74651931
123MP0005375_adipose_tissue_phenotype0.72049842
124MP0003091_abnormal_cell_migration0.71924481
125MP0001849_ear_inflammation0.70743675
126MP0004130_abnormal_muscle_cell0.70174835
127MP0002085_abnormal_embryonic_tissue0.70145067
128MP0003279_aneurysm0.67581153
129MP0010630_abnormal_cardiac_muscle0.67256998
130MP0003943_abnormal_hepatobiliary_system0.65498028

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)4.73961255
2Recurrent viral infections (HP:0004429)2.99205929
3T lymphocytopenia (HP:0005403)2.84935364
4Macroorchidism (HP:0000053)2.75616773
5Recurrent fungal infections (HP:0002841)2.66040177
6Abnormality of T cell number (HP:0011839)2.63177723
7Prominent nose (HP:0000448)2.59717877
8Cutaneous melanoma (HP:0012056)2.56846050
9Broad face (HP:0000283)2.53861391
10Autoimmune thrombocytopenia (HP:0001973)2.50587525
11Dislocated radial head (HP:0003083)2.49136952
12Long eyelashes (HP:0000527)2.48227809
13Slow saccadic eye movements (HP:0000514)2.44120035
14Abnormal delayed hypersensitivity skin test (HP:0002963)2.43319581
15Gingivitis (HP:0000230)2.37675379
16Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.36425447
17Impulsivity (HP:0100710)2.33262766
18Abnormality of T cells (HP:0002843)2.30572821
19Hyperacusis (HP:0010780)2.30328472
20Dysmetric saccades (HP:0000641)2.30083299
21Heterotopia (HP:0002282)2.29636983
22Abnormality of the radial head (HP:0003995)2.28898497
23Spontaneous hematomas (HP:0007420)2.25871456
24Pustule (HP:0200039)2.24321575
25Fatigue (HP:0012378)2.24281595
26Obstructive sleep apnea (HP:0002870)2.24247646
27Prolonged bleeding time (HP:0003010)2.19831814
28Myocardial infarction (HP:0001658)2.17774397
29Ankyloglossia (HP:0010296)2.14000882
30Sandal gap (HP:0001852)2.13208343
31Asymmetry of the thorax (HP:0001555)2.12843410
32Colitis (HP:0002583)2.11747953
33Inflammation of the large intestine (HP:0002037)2.11249772
34Recurrent bronchitis (HP:0002837)2.10737022
35Anal stenosis (HP:0002025)2.10036933
36Gastrointestinal inflammation (HP:0004386)2.09721122
37Abnormality of macrophages (HP:0004311)2.08899090
38Persistence of primary teeth (HP:0006335)2.08454575
39Mediastinal lymphadenopathy (HP:0100721)2.07703184
40Abnormality of oral frenula (HP:0000190)2.07548679
41Eczematoid dermatitis (HP:0000976)2.03725848
42Abnormality of pyrimidine metabolism (HP:0004353)2.02881392
43Gastrointestinal infarctions (HP:0005244)2.02576564
44Increased IgE level (HP:0003212)2.01668704
45Recurrent skin infections (HP:0001581)2.01061270
46Deep palmar crease (HP:0006191)2.00755729
47Recurrent abscess formation (HP:0002722)2.00539764
48Basal cell carcinoma (HP:0002671)2.00379854
49IgM deficiency (HP:0002850)2.00031386
50Recurrent bacterial skin infections (HP:0005406)1.99738195
51Abnormality of T cell physiology (HP:0011840)1.99440420
52Chromosomal breakage induced by crosslinking agents (HP:0003221)1.99292141
53Sparse lateral eyebrow (HP:0005338)1.98421821
54Neonatal hypoglycemia (HP:0001998)1.98198518
55Periodontitis (HP:0000704)1.97241715
56Cellulitis (HP:0100658)1.96375332
57Myelodysplasia (HP:0002863)1.96126026
58Depressed nasal tip (HP:0000437)1.95821354
59Joint swelling (HP:0001386)1.95226279
60Ectopic kidney (HP:0000086)1.92766991
61Panhypogammaglobulinemia (HP:0003139)1.92593568
62Pelvic girdle muscle weakness (HP:0003749)1.92543423
63Hypoglycemic coma (HP:0001325)1.92283072
64Hypoplasia of the thymus (HP:0000778)1.92062135
65Myositis (HP:0100614)1.91757274
66Entropion (HP:0000621)1.88998068
67Hyperglycemia (HP:0003074)1.87169971
68Nasal polyposis (HP:0100582)1.85791641
69Germ cell neoplasia (HP:0100728)1.85332740
70Cerebral aneurysm (HP:0004944)1.85140941
71Ulnar bowing (HP:0003031)1.84414690
72Chromsome breakage (HP:0040012)1.84265726
73Multiple enchondromatosis (HP:0005701)1.83977052
74Hyperinsulinemic hypoglycemia (HP:0000825)1.83174978
75Frequent falls (HP:0002359)1.82707771
76Abnormality of monocarboxylic acid metabolism (HP:0010996)1.82594959
77Subacute progressive viral hepatitis (HP:0006572)1.82524660
78Narrow palate (HP:0000189)1.82379347
79Thyroiditis (HP:0100646)1.81960354
80Difficulty running (HP:0009046)1.80417649
81Urethral obstruction (HP:0000796)1.80013672
82Aneurysm (HP:0002617)1.76979550
83Autoimmune hemolytic anemia (HP:0001890)1.76692524
84IgG deficiency (HP:0004315)1.75983145
85Coarse hair (HP:0002208)1.75911389
86Recurrent gram-negative bacterial infections (HP:0005420)1.74950240
87Hematochezia (HP:0002573)1.74949788
88Pseudobulbar signs (HP:0002200)1.74918642
89Meningitis (HP:0001287)1.74350892
90IgA deficiency (HP:0002720)1.73850201
91Interstitial pulmonary disease (HP:0006530)1.73355958
92Abnormality of the common coagulation pathway (HP:0010990)1.73126135
93Truncal obesity (HP:0001956)1.73062348
94Leukopenia (HP:0001882)1.73044232
95Malnutrition (HP:0004395)1.72731522
96Thin bony cortex (HP:0002753)1.72465352
97Abnormal platelet volume (HP:0011876)1.72050716
98Lymphopenia (HP:0001888)1.71670778
99Flat acetabular roof (HP:0003180)1.71503426
100Osteolytic defects of the phalanges of the hand (HP:0009771)1.71498859
101Osteolytic defects of the hand bones (HP:0009699)1.71498859
102Elfin facies (HP:0004428)1.70668884
103Abnormality of cells of the lymphoid lineage (HP:0012140)1.68992132
104Volvulus (HP:0002580)1.68216039
105Skin tags (HP:0010609)1.68131245
106Metaphyseal cupping (HP:0003021)1.67603534
107Agammaglobulinemia (HP:0004432)1.66990568
108Hepatitis (HP:0012115)1.66165207
109Combined immunodeficiency (HP:0005387)1.65881792
110Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.65664324
111Chronic diarrhea (HP:0002028)1.65165075
112Prominent metopic ridge (HP:0005487)1.64359018
113Lip pit (HP:0100267)1.64184011
114Disproportionate tall stature (HP:0001519)1.63727319
115Spondylolisthesis (HP:0003302)1.63672804
116Recurrent cutaneous fungal infections (HP:0011370)1.63274415
117Chronic mucocutaneous candidiasis (HP:0002728)1.63274415
118High pitched voice (HP:0001620)1.63058253
119Gingival bleeding (HP:0000225)1.62090232
120Abnormality of the distal phalanx of the thumb (HP:0009617)1.61794712
121Seborrheic dermatitis (HP:0001051)1.61701505
122Increased serum ferritin (HP:0003281)1.61490573
123Cafe-au-lait spot (HP:0000957)1.61431379
124Abnormality of iron homeostasis (HP:0011031)1.60940424
125Low anterior hairline (HP:0000294)1.59770065
126Arterial thrombosis (HP:0004420)1.59541021
127Vasculitis (HP:0002633)1.59262484
128Acute myeloid leukemia (HP:0004808)1.58961107
129Chronic otitis media (HP:0000389)1.58822924
130Syringomyelia (HP:0003396)1.58207315
131Spinal cord lesions (HP:0100561)1.58207315
132Dilatation of the ascending aorta (HP:0005111)1.57625066
133Abnormality of the thoracic spine (HP:0100711)1.57223909
134Abnormality of sulfur amino acid metabolism (HP:0004339)1.56651906
135Abnormality of chromosome stability (HP:0003220)1.56622530
136Onion bulb formation (HP:0003383)1.56179374
137Abnormality of transition element cation homeostasis (HP:0011030)1.55819355
138Reticulocytosis (HP:0001923)1.55786191
139Epistaxis (HP:0000421)1.55358990
140Deep philtrum (HP:0002002)1.54699968
141B lymphocytopenia (HP:0010976)1.53914074
142Abnormality of B cell number (HP:0010975)1.53914074
143Osteomyelitis (HP:0002754)1.53890173
144Chest pain (HP:0100749)1.53860577
145Abnormality of the columella (HP:0009929)1.53671021
146Basal ganglia calcification (HP:0002135)1.52978954
147Viral hepatitis (HP:0006562)1.52450543
148Mitral stenosis (HP:0001718)1.52390913
149Mitral valve prolapse (HP:0001634)1.52346925
150Radial bowing (HP:0002986)1.52178063
151Verrucae (HP:0200043)1.51850324
152Papilloma (HP:0012740)1.51850324
153Ependymoma (HP:0002888)1.51712038
154Hemorrhage of the eye (HP:0011885)1.51688015
155Gastrointestinal stroma tumor (HP:0100723)1.51673406
156Obstructive lung disease (HP:0006536)1.51208782
157Chronic obstructive pulmonary disease (HP:0006510)1.51208782
158Increased connective tissue (HP:0009025)1.50177852
159Bowel incontinence (HP:0002607)1.50070927

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK124.25045117
2BRD43.22410081
3PRPF4B3.17307184
4MAP4K13.00903059
5MAP3K102.67393142
6TAOK32.45283036
7RIPK42.35549028
8EEF2K2.21272662
9MAP3K132.13777070
10ERN11.98833403
11NEK21.98229390
12TRIB31.95522875
13SMG11.91880889
14MAP3K141.89902236
15BLK1.82953122
16RIPK11.81408321
17CDC71.73214011
18TXK1.71484937
19LATS11.65916421
20JAK31.64717952
21MARK31.60513077
22NEK91.59366980
23CAMK1D1.51949732
24STK31.51111011
25PASK1.49511588
26PKN21.48531318
27MARK21.45790524
28STK101.43917868
29PIM11.42749334
30SIK11.41308629
31CDC42BPA1.37894035
32ALK1.34748376
33TYK21.34656153
34TTN1.32072308
35MTOR1.28473138
36CHUK1.25681059
37JAK11.25003762
38STK41.24979906
39INSRR1.23919434
40CAMK1G1.22160579
41RPS6KA41.20034236
42FGFR41.18404146
43FRK1.16841230
44ZAP701.16140295
45PTK61.15707784
46FGFR21.14831079
47TRPM71.13131869
48ATR1.13108436
49KSR21.09866251
50CDK41.09763908
51ITK1.07661924
52FES1.07520778
53BTK1.04078290
54BMX0.98653105
55BRSK20.98141814
56MAP3K80.95809179
57MELK0.94145341
58IRAK30.93936383
59TTK0.93037647
60FGFR30.92916054
61CHEK10.92892247
62TNK20.92518897
63SGK30.92157346
64NLK0.90431420
65RET0.89055339
66SIK30.88815127
67STK38L0.86833222
68CSK0.86753994
69EPHB10.86209589
70YES10.85246144
71WNK10.83913286
72FLT30.83697245
73IKBKB0.82085871
74PDK10.81824108
75GRK60.80245471
76SIK20.79420176
77PLK10.79145991
78MKNK20.79136563
79AURKB0.78756888
80TYRO30.78314444
81CDK60.76060784
82MAPK110.75453499
83MAPK120.75175828
84HIPK20.73916913
85MAP2K30.72756195
86CSF1R0.71926674
87AKT30.71598542
88PDPK10.70746192
89TBK10.70638737
90JAK20.70627131
91IKBKE0.69862250
92HCK0.69784632
93CDK70.68540149
94WEE10.66700132
95ZAK0.65370634
96ATM0.64584686
97MAP3K10.63742163
98LRRK20.63481708
99CDK20.61838828
100TEC0.61573628
101SCYL20.60542407
102MAPK70.59322168
103DYRK30.58952445
104PRKD20.58178518
105SGK20.58136352
106DYRK1B0.57900071
107MAP3K20.57791458
108PDGFRB0.57754624
109TSSK60.57716823
110LCK0.57158667
111PRKD30.55141590
112PDGFRA0.54852752
113NEK60.54493828
114SYK0.54170054
115LYN0.53911022
116PRKCH0.53285099
117RPS6KB20.53005293
118PRKAA20.52597125
119FGR0.52141160
120MAP3K60.51849340
121PRKAA10.51060438
122MAP3K70.50531526
123CAMKK10.46962859
124CHEK20.46511670
125KSR10.46502756
126PIK3CG0.45977460
127MAP2K20.45906787
128RPS6KC10.45515890
129RPS6KL10.45515890
130MAP3K30.45359955
131PAK40.44649333
132CDK10.43732828
133TGFBR20.42770143
134MKNK10.42310779
135PLK30.41714308
136IRAK40.41219819
137TAOK10.40848659
138RPS6KB10.39461310
139ICK0.38658228
140AKT20.37660684

Predicted pathways (KEGG)

RankGene SetZ-score
1One carbon pool by folate_Homo sapiens_hsa006702.75508713
2NF-kappa B signaling pathway_Homo sapiens_hsa040642.32641200
3Lysine degradation_Homo sapiens_hsa003102.29291697
4Other glycan degradation_Homo sapiens_hsa005112.17768085
5Primary immunodeficiency_Homo sapiens_hsa053402.06402625
6Base excision repair_Homo sapiens_hsa034101.81744422
7Intestinal immune network for IgA production_Homo sapiens_hsa046721.80520640
8Antigen processing and presentation_Homo sapiens_hsa046121.79339245
9Selenocompound metabolism_Homo sapiens_hsa004501.71124349
10RNA transport_Homo sapiens_hsa030131.60520747
11Caffeine metabolism_Homo sapiens_hsa002321.60461596
12Maturity onset diabetes of the young_Homo sapiens_hsa049501.56434907
13DNA replication_Homo sapiens_hsa030301.53161823
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.52540173
15VEGF signaling pathway_Homo sapiens_hsa043701.51208658
16Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.49072855
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.48942344
18Legionellosis_Homo sapiens_hsa051341.47144992
19Measles_Homo sapiens_hsa051621.46582007
20Herpes simplex infection_Homo sapiens_hsa051681.44896742
21Renal cell carcinoma_Homo sapiens_hsa052111.44348278
22B cell receptor signaling pathway_Homo sapiens_hsa046621.43823129
23Chronic myeloid leukemia_Homo sapiens_hsa052201.43759832
24AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.43710168
25Viral carcinogenesis_Homo sapiens_hsa052031.42248609
26Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.41012988
27Choline metabolism in cancer_Homo sapiens_hsa052311.36352613
28Mismatch repair_Homo sapiens_hsa034301.34892917
29Small cell lung cancer_Homo sapiens_hsa052221.31846423
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.30684363
31Colorectal cancer_Homo sapiens_hsa052101.29437550
32mRNA surveillance pathway_Homo sapiens_hsa030151.29355273
33Cell cycle_Homo sapiens_hsa041101.28686666
34Thyroid cancer_Homo sapiens_hsa052161.27294380
35Osteoclast differentiation_Homo sapiens_hsa043801.26568575
36Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.25132539
37mTOR signaling pathway_Homo sapiens_hsa041501.24616916
38Glioma_Homo sapiens_hsa052141.24298469
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.22410690
40Apoptosis_Homo sapiens_hsa042101.22179452
41Insulin resistance_Homo sapiens_hsa049311.22000492
42p53 signaling pathway_Homo sapiens_hsa041151.21078077
43Phospholipase D signaling pathway_Homo sapiens_hsa040721.17331446
44Acute myeloid leukemia_Homo sapiens_hsa052211.17204412
45HTLV-I infection_Homo sapiens_hsa051661.16189243
46ErbB signaling pathway_Homo sapiens_hsa040121.15475396
47T cell receptor signaling pathway_Homo sapiens_hsa046601.14841732
48TNF signaling pathway_Homo sapiens_hsa046681.12815287
49MicroRNAs in cancer_Homo sapiens_hsa052061.11607587
50ABC transporters_Homo sapiens_hsa020101.09237467
51Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.08274271
52Staphylococcus aureus infection_Homo sapiens_hsa051501.06881303
53Systemic lupus erythematosus_Homo sapiens_hsa053221.06586374
54Platelet activation_Homo sapiens_hsa046111.06407294
55Transcriptional misregulation in cancer_Homo sapiens_hsa052021.02557145
56Fructose and mannose metabolism_Homo sapiens_hsa000511.02156727
57Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.01617007
58Influenza A_Homo sapiens_hsa051641.00921047
59Spliceosome_Homo sapiens_hsa030401.00143317
60Leishmaniasis_Homo sapiens_hsa051400.99702804
61Jak-STAT signaling pathway_Homo sapiens_hsa046300.99213233
62Epstein-Barr virus infection_Homo sapiens_hsa051690.99008800
63Chemokine signaling pathway_Homo sapiens_hsa040620.98711416
64Insulin signaling pathway_Homo sapiens_hsa049100.98111524
65Hematopoietic cell lineage_Homo sapiens_hsa046400.97558838
66Toll-like receptor signaling pathway_Homo sapiens_hsa046200.97311202
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.96573062
68Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.95542234
69GnRH signaling pathway_Homo sapiens_hsa049120.95168784
70Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.92412422
71Graft-versus-host disease_Homo sapiens_hsa053320.90604374
72Drug metabolism - other enzymes_Homo sapiens_hsa009830.90230506
73Hepatitis B_Homo sapiens_hsa051610.90085547
74Toxoplasmosis_Homo sapiens_hsa051450.88985003
75Dorso-ventral axis formation_Homo sapiens_hsa043200.88824495
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.87595021
77Carbohydrate digestion and absorption_Homo sapiens_hsa049730.86799966
78Arginine biosynthesis_Homo sapiens_hsa002200.86104317
79Viral myocarditis_Homo sapiens_hsa054160.83425733
80RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.83101015
81Estrogen signaling pathway_Homo sapiens_hsa049150.82787546
82Biosynthesis of amino acids_Homo sapiens_hsa012300.82583410
83Homologous recombination_Homo sapiens_hsa034400.81336137
84Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.80877145
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.80856482
86Pentose phosphate pathway_Homo sapiens_hsa000300.79088135
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.79037202
88Sphingolipid signaling pathway_Homo sapiens_hsa040710.78059913
89RNA degradation_Homo sapiens_hsa030180.76413303
90Bladder cancer_Homo sapiens_hsa052190.75771302
91HIF-1 signaling pathway_Homo sapiens_hsa040660.75341340
92Proteoglycans in cancer_Homo sapiens_hsa052050.75107563
93Notch signaling pathway_Homo sapiens_hsa043300.74290323
94Type II diabetes mellitus_Homo sapiens_hsa049300.73890743
95Cysteine and methionine metabolism_Homo sapiens_hsa002700.73729631
96Complement and coagulation cascades_Homo sapiens_hsa046100.73655446
97Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.70947368
98Adherens junction_Homo sapiens_hsa045200.70808031
99Thyroid hormone signaling pathway_Homo sapiens_hsa049190.70446688
100Focal adhesion_Homo sapiens_hsa045100.70341584
101Autoimmune thyroid disease_Homo sapiens_hsa053200.70144532
102Adipocytokine signaling pathway_Homo sapiens_hsa049200.69215708
103Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68926793
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.68235028
105Vitamin digestion and absorption_Homo sapiens_hsa049770.68124959
106Inositol phosphate metabolism_Homo sapiens_hsa005620.67709980
107Sulfur relay system_Homo sapiens_hsa041220.67056742
108Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.66421856
109Fanconi anemia pathway_Homo sapiens_hsa034600.66377576
110Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64633937
111Non-small cell lung cancer_Homo sapiens_hsa052230.64039892
112Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.63303652
113Malaria_Homo sapiens_hsa051440.62754020
114Pancreatic cancer_Homo sapiens_hsa052120.62041377
115Nucleotide excision repair_Homo sapiens_hsa034200.61876986
116Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.61597119
117FoxO signaling pathway_Homo sapiens_hsa040680.60983337
118Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60440314
119MAPK signaling pathway_Homo sapiens_hsa040100.59381826
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58659419
121Prostate cancer_Homo sapiens_hsa052150.58655326
122Type I diabetes mellitus_Homo sapiens_hsa049400.58373129
123Tuberculosis_Homo sapiens_hsa051520.57910032
124AMPK signaling pathway_Homo sapiens_hsa041520.56028395
125Amoebiasis_Homo sapiens_hsa051460.55559361
126Long-term potentiation_Homo sapiens_hsa047200.54941197
127Glycerophospholipid metabolism_Homo sapiens_hsa005640.54234553
128Endocytosis_Homo sapiens_hsa041440.53993678
129Pathways in cancer_Homo sapiens_hsa052000.53803759
130Longevity regulating pathway - mammal_Homo sapiens_hsa042110.53421625
131Non-homologous end-joining_Homo sapiens_hsa034500.53242864
132Prolactin signaling pathway_Homo sapiens_hsa049170.52040498
133Glucagon signaling pathway_Homo sapiens_hsa049220.51248321
134Glycosaminoglycan degradation_Homo sapiens_hsa005310.50589150
135Allograft rejection_Homo sapiens_hsa053300.49043116
136Endometrial cancer_Homo sapiens_hsa052130.46583838
137Galactose metabolism_Homo sapiens_hsa000520.46461099
138Phosphatidylinositol signaling system_Homo sapiens_hsa040700.46350333
139Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.45928508
140Nitrogen metabolism_Homo sapiens_hsa009100.45419075
141Hepatitis C_Homo sapiens_hsa051600.45214370

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