ZBTB5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1histone H3-K36 demethylation (GO:0070544)5.46392230
2pyrimidine nucleobase catabolic process (GO:0006208)5.20735820
3negative regulation of fibroblast apoptotic process (GO:2000270)4.90611605
4macroautophagy (GO:0016236)4.81724005
5nuclear pore complex assembly (GO:0051292)4.45562947
6mitotic chromosome condensation (GO:0007076)4.40942599
7cellular extravasation (GO:0045123)4.24601096
8regulation of histone H3-K9 methylation (GO:0051570)4.10078497
9regulation of triglyceride catabolic process (GO:0010896)4.05778064
10negative regulation of histone methylation (GO:0031061)4.02210552
11mitotic sister chromatid cohesion (GO:0007064)4.01324853
12positive regulation of B cell differentiation (GO:0045579)3.92153380
13heart valve formation (GO:0003188)3.89098348
14regulation of NFAT protein import into nucleus (GO:0051532)3.87505102
15peptidyl-lysine dimethylation (GO:0018027)3.77548657
16nucleosome disassembly (GO:0006337)3.74291123
17protein-DNA complex disassembly (GO:0032986)3.74291123
18nucleobase catabolic process (GO:0046113)3.70559200
19regulation of chromatin binding (GO:0035561)3.62890673
20nuclear pore organization (GO:0006999)3.59522465
21histone H3-K4 trimethylation (GO:0080182)3.55106772
22monoubiquitinated protein deubiquitination (GO:0035520)3.53699824
23histone H3-K9 methylation (GO:0051567)3.52245649
24hepatocyte apoptotic process (GO:0097284)3.51349738
25histone lysine demethylation (GO:0070076)3.51256248
26dosage compensation (GO:0007549)3.46314541
27regulation of fibroblast apoptotic process (GO:2000269)3.45124821
28cilium or flagellum-dependent cell motility (GO:0001539)3.43972366
29negative regulation of DNA repair (GO:0045738)3.39194175
30pore complex assembly (GO:0046931)3.35566362
31mitotic sister chromatid segregation (GO:0000070)3.33556168
32histone demethylation (GO:0016577)3.31306661
33histone H3-K9 demethylation (GO:0033169)3.30869596
34RNA localization (GO:0006403)3.30668450
35histone H4-K16 acetylation (GO:0043984)3.30623516
36heterochromatin organization (GO:0070828)3.27040010
37protein dealkylation (GO:0008214)3.26160990
38protein demethylation (GO:0006482)3.26160990
39histone H3-K9 modification (GO:0061647)3.25462250
40glucocorticoid receptor signaling pathway (GO:0042921)3.24853972
41alpha-linolenic acid metabolic process (GO:0036109)3.21830253
42regulation of histone methylation (GO:0031060)3.19623975
43microtubule depolymerization (GO:0007019)3.18854724
44mitotic nuclear envelope disassembly (GO:0007077)3.17484511
45nuclear envelope disassembly (GO:0051081)3.15157119
46membrane disassembly (GO:0030397)3.15157119
47body morphogenesis (GO:0010171)3.14487599
48acrosome assembly (GO:0001675)3.13325596
49regulation of RNA export from nucleus (GO:0046831)3.10795120
50embryonic body morphogenesis (GO:0010172)3.10600913
51regulation of DNA damage checkpoint (GO:2000001)3.07819247
52regulation of translational fidelity (GO:0006450)3.03293597
53spliceosomal tri-snRNP complex assembly (GO:0000244)3.02790420
54peptidyl-lysine methylation (GO:0018022)3.01083374
55histone H4-K5 acetylation (GO:0043981)3.00124831
56histone H4-K8 acetylation (GO:0043982)3.00124831
57ATP-dependent chromatin remodeling (GO:0043044)2.99082731
58NLS-bearing protein import into nucleus (GO:0006607)2.97758224
59DNA topological change (GO:0006265)2.97701650
60pre-miRNA processing (GO:0031054)2.96785530
61peptidyl-lysine trimethylation (GO:0018023)2.96514879
62positive regulation of histone deacetylation (GO:0031065)2.95828845
63positive regulation by host of viral transcription (GO:0043923)2.95265139
64cytoplasmic mRNA processing body assembly (GO:0033962)2.94682656
65atrioventricular valve morphogenesis (GO:0003181)2.92612186
66histone lysine methylation (GO:0034968)2.92194232
67meiotic chromosome segregation (GO:0045132)2.92128408
68positive regulation of gene expression, epigenetic (GO:0045815)2.91489124
69sperm-egg recognition (GO:0035036)2.90422027
70phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.89537835
71positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.88949951
72T cell migration (GO:0072678)2.88880479
73regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.88468923
74histone H3-K4 methylation (GO:0051568)2.85835656
75corticosteroid receptor signaling pathway (GO:0031958)2.85319833
76DNA unwinding involved in DNA replication (GO:0006268)2.85318386
77growth hormone receptor signaling pathway (GO:0060396)2.81343400
78binding of sperm to zona pellucida (GO:0007339)2.81287057
79histone H2B ubiquitination (GO:0033523)2.79254035
80regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.79090205
81regulation of histone H3-K27 methylation (GO:0061085)2.78669822
82embryonic retina morphogenesis in camera-type eye (GO:0060059)2.76277691
83DNA duplex unwinding (GO:0032508)2.75594680
84insulin-like growth factor receptor signaling pathway (GO:0048009)2.75494351
85mast cell activation involved in immune response (GO:0002279)2.73811534
86mast cell degranulation (GO:0043303)2.73811534
87negative regulation of gene expression, epigenetic (GO:0045814)2.71881184
88regulation of histone H3-K4 methylation (GO:0051569)2.70997531
89atrial septum morphogenesis (GO:0060413)2.70531531
90camera-type eye morphogenesis (GO:0048593)2.70189793
91Notch signaling involved in heart development (GO:0061314)2.67918141
92histone deubiquitination (GO:0016578)2.66359884
93acrosome reaction (GO:0007340)2.66073006
94protein localization to chromosome (GO:0034502)2.65530426
95regulation of centrosome cycle (GO:0046605)2.63742301
96negative regulation of histone modification (GO:0031057)2.63555506
97protein localization to chromosome, centromeric region (GO:0071459)2.63267759
98nuclear envelope organization (GO:0006998)2.62909203
99regulation of spindle organization (GO:0090224)2.61835080
100cell-cell recognition (GO:0009988)2.61474805
101protein polyglutamylation (GO:0018095)2.61117687
102regulation of sister chromatid cohesion (GO:0007063)2.60986111
103regulation of centrosome duplication (GO:0010824)2.60969609
104nucleosome organization (GO:0034728)2.59012038
105histone methylation (GO:0016571)2.57999764
106DNA geometric change (GO:0032392)2.57962174
107nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.57341913
108DNA damage response, signal transduction resulting in transcription (GO:0042772)2.55948640
109DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.53088623
110regulation of B cell differentiation (GO:0045577)2.51340631
111DNA alkylation (GO:0006305)2.50683199
112DNA methylation (GO:0006306)2.50683199
113sister chromatid cohesion (GO:0007062)2.50119795
114microtubule severing (GO:0051013)2.49985776
115axonal fasciculation (GO:0007413)2.49549126
116histone H4 deacetylation (GO:0070933)2.49239081
117DNA synthesis involved in DNA repair (GO:0000731)2.48288129
118regulation of microtubule depolymerization (GO:0031114)2.48178319
119histone mRNA catabolic process (GO:0071044)2.46602364
120negative regulation of chromatin modification (GO:1903309)2.46093547
121cell migration in hindbrain (GO:0021535)2.46006935
122notochord development (GO:0030903)2.44671889
123RNA stabilization (GO:0043489)2.43899223
124mRNA stabilization (GO:0048255)2.43899223
125histone exchange (GO:0043486)2.43400779
126chromatin assembly (GO:0031497)2.41925760
127negative regulation of microtubule depolymerization (GO:0007026)2.41178955
128chromosome condensation (GO:0030261)2.41092194
129urea cycle (GO:0000050)2.40550351
130urea metabolic process (GO:0019627)2.40550351
131linoleic acid metabolic process (GO:0043651)2.40360700
132neuronal stem cell maintenance (GO:0097150)2.39331989
133translesion synthesis (GO:0019985)2.38666504
134fusion of sperm to egg plasma membrane (GO:0007342)2.38571767
135morphogenesis of an epithelial sheet (GO:0002011)2.38292016
136peptidyl-threonine phosphorylation (GO:0018107)2.37882410
137protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.37357074
138DNA conformation change (GO:0071103)2.37117715
139protein export from nucleus (GO:0006611)2.36090514
140response to UV-C (GO:0010225)2.35981474
141mRNA cleavage (GO:0006379)2.35029509
142skeletal muscle organ development (GO:0060538)2.34831746
143gene silencing (GO:0016458)2.33651743
144histone H4 acetylation (GO:0043967)2.33544890
145regulation of centriole replication (GO:0046599)2.33321650
146gene silencing by RNA (GO:0031047)2.33309141
147resolution of meiotic recombination intermediates (GO:0000712)2.33191711
148cellular response to growth hormone stimulus (GO:0071378)2.33116490
149male meiosis (GO:0007140)2.32871308
150internal peptidyl-lysine acetylation (GO:0018393)2.32822172
151histone acetylation (GO:0016573)2.32680223
152sperm motility (GO:0030317)2.32620930
153eye morphogenesis (GO:0048592)2.31450467
154epithelial cilium movement (GO:0003351)2.30050546
155genitalia morphogenesis (GO:0035112)2.30036496
156protein-DNA complex subunit organization (GO:0071824)2.29938636
157regulation of interleukin-12 biosynthetic process (GO:0045075)2.29905501
158demethylation (GO:0070988)2.29355793
159regulation of nucleobase-containing compound transport (GO:0032239)2.29213954
160sister chromatid segregation (GO:0000819)2.29106708
161stress granule assembly (GO:0034063)2.29014832
162positive regulation of gamma-delta T cell activation (GO:0046645)2.28563083
163maternal placenta development (GO:0001893)2.27647469
164ethanol oxidation (GO:0006069)2.27532373
165protein localization to kinetochore (GO:0034501)2.26320814
166motile cilium assembly (GO:0044458)2.26282970
167negative regulation of B cell proliferation (GO:0030889)2.26043555

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.16648461
2* FOXM1_23109430_ChIP-Seq_U2OS_Human5.10930134
3MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.85645892
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.58456586
5MYC_22102868_ChIP-Seq_BL_Human3.35597002
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.28630579
7STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse3.15071405
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.03176405
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.76494391
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.68883452
11* TP63_19390658_ChIP-ChIP_HaCaT_Human2.67093392
12ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.64199362
13PKCTHETA_26484144_Chip-Seq_BREAST_Human2.51041203
14SCL_19346495_ChIP-Seq_HPC-7_Human2.41601731
15CIITA_25753668_ChIP-Seq_RAJI_Human2.36179688
16E2F4_17652178_ChIP-ChIP_JURKAT_Human2.31708364
17TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.27932917
18* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.27456614
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.14724439
20TCF7_22412390_ChIP-Seq_EML_Mouse2.13432883
21IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.03376860
22ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.00645405
23SALL1_21062744_ChIP-ChIP_HESCs_Human1.95844570
24EZH2_22144423_ChIP-Seq_EOC_Human1.93847800
25KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.92191805
26* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.90081694
27KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.88049257
28TP63_17297297_ChIP-ChIP_HaCaT_Human1.81857152
29* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.80146871
30KDM2B_26808549_Chip-Seq_DND41_Human1.76368522
31DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.76347329
32EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.76219059
33MYC_18555785_ChIP-Seq_MESCs_Mouse1.75741650
34WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.75176338
35GATA1_22025678_ChIP-Seq_K562_Human1.73266022
36FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.73089172
37AR_21909140_ChIP-Seq_LNCAP_Human1.71632324
38* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.69903312
39* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.65386640
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.64190873
41PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.64160332
42DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.60223300
43HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.59818650
44NOTCH1_21737748_ChIP-Seq_TLL_Human1.59103946
45* VDR_21846776_ChIP-Seq_THP-1_Human1.55599164
46MAF_26560356_Chip-Seq_TH1_Human1.54824771
47RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.51142432
48ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49887258
49NFIB_24661679_ChIP-Seq_LUNG_Mouse1.47250731
50ZFP281_18757296_ChIP-ChIP_E14_Mouse1.45821204
51UTX_26944678_Chip-Seq_JUKART_Human1.45238768
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.43291696
53NCOR1_26117541_ChIP-Seq_K562_Human1.42134222
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40320037
55E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.39364446
56* MYC_19079543_ChIP-ChIP_MESCs_Mouse1.38571206
57* NANOG_21062744_ChIP-ChIP_HESCs_Human1.38193623
58ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.33727187
59GATA1_26923725_Chip-Seq_HPCs_Mouse1.33057186
60CHD1_26751641_Chip-Seq_LNCaP_Human1.32280798
61* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.32023085
62E2F1_21310950_ChIP-Seq_MCF-7_Human1.30556553
63SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.29741469
64ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.29570515
65CREB1_26743006_Chip-Seq_LNCaP_Human1.27995812
66RXR_22158963_ChIP-Seq_LIVER_Mouse1.27753523
67KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.25993248
68YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.25288154
69CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.25230411
70PPARA_22158963_ChIP-Seq_LIVER_Mouse1.25208433
71CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.24526172
72KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.23855240
73SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.23254300
74P300_27058665_Chip-Seq_ZR-75-30cells_Human1.22261810
75* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.21485126
76* VDR_24763502_ChIP-Seq_THP-1_Human1.20628334
77* MYB_26560356_Chip-Seq_TH2_Human1.19776496
78FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.18803033
79* SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.17445649
80SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16802274
81SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.16693289
82XRN2_22483619_ChIP-Seq_HELA_Human1.16127101
83NELFA_20434984_ChIP-Seq_ESCs_Mouse1.14743529
84POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.14125010
85TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14125010
86CLOCK_20551151_ChIP-Seq_293T_Human1.13214345
87MYCN_18555785_ChIP-Seq_MESCs_Mouse1.12489344
88WT1_19549856_ChIP-ChIP_CCG9911_Human1.12394241
89EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.12300532
90ELK4_26923725_Chip-Seq_MESODERM_Mouse1.12143116
91* MYB_26560356_Chip-Seq_TH1_Human1.11816355
92EGR1_23403033_ChIP-Seq_LIVER_Mouse1.11497057
93ZFP281_27345836_Chip-Seq_ESCs_Mouse1.10592527
94* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09243418
95KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.09231851
96KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.09231851
97KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.09231851
98BRD4_27068464_Chip-Seq_AML-cells_Mouse1.08716954
99TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.08196500
100RACK7_27058665_Chip-Seq_MCF-7_Human1.08119789
101* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.08002816
102PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.07776999
103KDM5A_27292631_Chip-Seq_BREAST_Human1.07590183
104E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06811504
105TTF2_22483619_ChIP-Seq_HELA_Human1.06682828
106TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.06573155
107KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.05531462
108KDM2B_26808549_Chip-Seq_JURKAT_Human1.05156335
109NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.04768343
110RUNX1_27514584_Chip-Seq_MCF-7_Human1.04609503
111* FOXP3_21729870_ChIP-Seq_TREG_Human1.04303530
112KDM2B_26808549_Chip-Seq_SUP-B15_Human1.01674803
113EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.01539606
114* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.00822717
115IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.99805274
116NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.99327886
117MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.99085518
118UBF1/2_26484160_Chip-Seq_HMECs_Human0.99073360
119GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.98929363
120CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.98616520
121NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.97796275
122ETS1_22383799_ChIP-Seq_G1ME_Mouse0.96776777
123IRF8_27001747_Chip-Seq_BMDM_Mouse0.96004973
124RING1B_27294783_Chip-Seq_NPCs_Mouse0.95941346
125RUNX1_26923725_Chip-Seq_HPCs_Mouse0.95363744
126NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.95132165
127TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.94507156
128* KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94378023
129HOXB4_20404135_ChIP-ChIP_EML_Mouse0.94263576
130* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.94120533
131PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93905617
132OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93011463
133HIF1A_21447827_ChIP-Seq_MCF-7_Human0.92953512
134* RUNX1_22412390_ChIP-Seq_EML_Mouse0.92853355
135ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.92489159
136SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.91413891
137MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.88766619
138ELK3_25401928_ChIP-Seq_HUVEC_Human0.88339729
139* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88279417
140KDM2B_26808549_Chip-Seq_K562_Human0.88044487
141VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.87507308
142ISL1_27105846_Chip-Seq_CPCs_Mouse0.87418485
143TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.87374569
144FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.85585077

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation3.10221217
2MP0002653_abnormal_ependyma_morphology2.81742248
3MP0008007_abnormal_cellular_replicative2.65821935
4MP0002396_abnormal_hematopoietic_system2.63266389
5MP0003693_abnormal_embryo_hatching2.40545393
6MP0002138_abnormal_hepatobiliary_system2.39120314
7MP0005410_abnormal_fertilization2.27237928
8MP0000566_synostosis2.23343370
9MP0003172_abnormal_lysosome_physiology2.22734597
10MP0000537_abnormal_urethra_morphology2.14140579
11MP0003123_paternal_imprinting2.12749634
12MP0003111_abnormal_nucleus_morphology2.11186350
13MP0005409_darkened_coat_color2.10975264
14MP0005076_abnormal_cell_differentiation2.05434735
15MP0002139_abnormal_hepatobiliary_system1.95203181
16MP0010094_abnormal_chromosome_stability1.93018491
17MP0002009_preneoplasia1.87365239
18MP0003183_abnormal_peptide_metabolism1.85878794
19MP0004808_abnormal_hematopoietic_stem1.85059316
20MP0003121_genomic_imprinting1.80551885
21MP0008995_early_reproductive_senescence1.80144281
22MP0005248_abnormal_Harderian_gland1.79917139
23MP0003122_maternal_imprinting1.77515547
24MP0003077_abnormal_cell_cycle1.73157122
25MP0002282_abnormal_trachea_morphology1.72298668
26MP0008058_abnormal_DNA_repair1.71680083
27MP0003890_abnormal_embryonic-extraembry1.63282340
28MP0010307_abnormal_tumor_latency1.62903843
29MP0005174_abnormal_tail_pigmentation1.62439112
30MP0002089_abnormal_postnatal_growth/wei1.59261116
31MP0003300_gastrointestinal_ulcer1.56673774
32MP0005220_abnormal_exocrine_pancreas1.56563156
33MP0003943_abnormal_hepatobiliary_system1.55916960
34MP0003436_decreased_susceptibility_to1.53971792
35MP0003115_abnormal_respiratory_system1.52978754
36MP0004957_abnormal_blastocyst_morpholog1.52806386
37MP0008877_abnormal_DNA_methylation1.50409071
38MP0003385_abnormal_body_wall1.48313566
39MP0001929_abnormal_gametogenesis1.48272974
40MP0000778_abnormal_nervous_system1.46710450
41MP0009672_abnormal_birth_weight1.46618748
42MP0010030_abnormal_orbit_morphology1.45738420
43MP0003303_peritoneal_inflammation1.43531361
44MP0002132_abnormal_respiratory_system1.42096434
45MP0004185_abnormal_adipocyte_glucose1.41527414
46MP0006054_spinal_hemorrhage1.38691784
47MP0008961_abnormal_basal_metabolism1.36158954
48MP0009278_abnormal_bone_marrow1.35703052
49MP0003698_abnormal_male_reproductive1.35271841
50MP0002233_abnormal_nose_morphology1.29957566
51MP0002928_abnormal_bile_duct1.29298694
52MP0002163_abnormal_gland_morphology1.29091456
53MP0002210_abnormal_sex_determination1.26026979
54MP0008057_abnormal_DNA_replication1.24908851
55MP0004233_abnormal_muscle_weight1.23011513
56MP0000703_abnormal_thymus_morphology1.22677884
57MP0004197_abnormal_fetal_growth/weight/1.22610346
58MP0003453_abnormal_keratinocyte_physiol1.22126065
59MP0000733_abnormal_muscle_development1.21593887
60MP0005365_abnormal_bile_salt1.21515358
61MP0003705_abnormal_hypodermis_morpholog1.19605026
62MP0005394_taste/olfaction_phenotype1.19549977
63MP0005499_abnormal_olfactory_system1.19549977
64MP0002092_abnormal_eye_morphology1.18890270
65MP0002877_abnormal_melanocyte_morpholog1.17238165
66MP0002697_abnormal_eye_size1.16461928
67MP0001984_abnormal_olfaction1.15561950
68MP0002398_abnormal_bone_marrow1.14934368
69MP0003942_abnormal_urinary_system1.14316663
70MP0001346_abnormal_lacrimal_gland1.13557452
71MP0003937_abnormal_limbs/digits/tail_de1.12270509
72MP0004264_abnormal_extraembryonic_tissu1.12036096
73MP0003755_abnormal_palate_morphology1.11930883
74MP0005451_abnormal_body_composition1.11760268
75MP0005423_abnormal_somatic_nervous1.11147840
76MP0003221_abnormal_cardiomyocyte_apopto1.09968525
77MP0002938_white_spotting1.09724311
78MP0003091_abnormal_cell_migration1.08699917
79MP0010352_gastrointestinal_tract_polyps1.07658153
80MP0000428_abnormal_craniofacial_morphol1.07304947
81MP0001835_abnormal_antigen_presentation1.06476867
82MP0002084_abnormal_developmental_patter1.05380929
83MP0001800_abnormal_humoral_immune1.04415667
84MP0001293_anophthalmia1.03722965
85MP0001145_abnormal_male_reproductive1.03704150
86MP0003861_abnormal_nervous_system1.01636680
87MP0001672_abnormal_embryogenesis/_devel1.01209790
88MP0005380_embryogenesis_phenotype1.01209790
89MP0003252_abnormal_bile_duct0.99777039
90MP0005666_abnormal_adipose_tissue0.99740626
91MP0008932_abnormal_embryonic_tissue0.99269454
92MP0000350_abnormal_cell_proliferation0.98817233
93MP0009703_decreased_birth_body0.97655671
94MP0002088_abnormal_embryonic_growth/wei0.97384088
95MP0000462_abnormal_digestive_system0.96751222
96MP0002081_perinatal_lethality0.96420019
97MP0005391_vision/eye_phenotype0.96201008
98MP0000534_abnormal_ureter_morphology0.96142606
99MP0000371_diluted_coat_color0.95901057
100MP0005187_abnormal_penis_morphology0.95662965
101MP0001730_embryonic_growth_arrest0.94885485
102MP0004885_abnormal_endolymph0.94125260
103MP0002161_abnormal_fertility/fecundity0.93088897
104MP0002085_abnormal_embryonic_tissue0.93032650
105MP0000432_abnormal_head_morphology0.92900189
106MP0003656_abnormal_erythrocyte_physiolo0.92707964
107MP0001915_intracranial_hemorrhage0.92318937
108MP0003567_abnormal_fetal_cardiomyocyte0.92253704
109MP0002111_abnormal_tail_morphology0.92100429
110MP0009840_abnormal_foam_cell0.92032375
111MP0005075_abnormal_melanosome_morpholog0.91715694
112MP0003119_abnormal_digestive_system0.91040174
113MP0003984_embryonic_growth_retardation0.89827143
114MP0008789_abnormal_olfactory_epithelium0.88960715
115MP0000653_abnormal_sex_gland0.88587209
116MP0004130_abnormal_muscle_cell0.88242413
117MP0001340_abnormal_eyelid_morphology0.87022732
118MP0003136_yellow_coat_color0.86616039
119MP0003699_abnormal_female_reproductive0.84241290
120MP0002722_abnormal_immune_system0.84069437
121MP0000579_abnormal_nail_morphology0.83958497
122MP0000465_gastrointestinal_hemorrhage0.83468394
123MP0000003_abnormal_adipose_tissue0.83078420
124MP0001697_abnormal_embryo_size0.82970102
125MP0002116_abnormal_craniofacial_bone0.82510506
126MP0002970_abnormal_white_adipose0.82137921
127MP0000689_abnormal_spleen_morphology0.81503356
128MP0010329_abnormal_lipoprotein_level0.81479982
129MP0000678_abnormal_parathyroid_gland0.80760584
130MP0000609_abnormal_liver_physiology0.80570383
131MP0000383_abnormal_hair_follicle0.80070833
132MP0002086_abnormal_extraembryonic_tissu0.79498137
133MP0001286_abnormal_eye_development0.79127439
134MP0000685_abnormal_immune_system0.78805182
135MP0002452_abnormal_antigen_presenting0.78345849
136MP0000313_abnormal_cell_death0.77757775
137MP0002152_abnormal_brain_morphology0.77631088
138MP0006292_abnormal_olfactory_placode0.76712654
139MP0003935_abnormal_craniofacial_develop0.76555847
140MP0000049_abnormal_middle_ear0.76315440
141MP0005464_abnormal_platelet_physiology0.75967019
142MP0002249_abnormal_larynx_morphology0.74386683
143MP0000015_abnormal_ear_pigmentation0.74032849
144MP0002080_prenatal_lethality0.73850144
145MP0000631_abnormal_neuroendocrine_gland0.73697185
146MP0009115_abnormal_fat_cell0.73497841

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.59034090
2Short 4th metacarpal (HP:0010044)4.59034090
3Anterior segment dysgenesis (HP:0007700)4.47124155
4Cerebellar dysplasia (HP:0007033)3.93208282
5Vertebral arch anomaly (HP:0008438)3.81623220
6Buphthalmos (HP:0000557)3.70652639
7Abnormality of the 4th metacarpal (HP:0010012)3.45831714
8Hyperacusis (HP:0010780)3.33100831
9Renovascular hypertension (HP:0100817)3.26826453
10Heterotopia (HP:0002282)3.24999766
11Ependymoma (HP:0002888)3.21261675
12Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.19816944
13Prostate neoplasm (HP:0100787)3.18111063
14Medulloblastoma (HP:0002885)3.04984522
15Male infertility (HP:0003251)2.99321946
16Renal duplication (HP:0000075)2.90000060
17Amaurosis fugax (HP:0100576)2.88992750
18Abnormality of the nasal septum (HP:0000419)2.82998601
19Overlapping toe (HP:0001845)2.82906892
20Ulnar bowing (HP:0003031)2.76029522
21Capillary hemangiomas (HP:0005306)2.75567642
22Elfin facies (HP:0004428)2.62231332
23Subacute progressive viral hepatitis (HP:0006572)2.61735719
24Impulsivity (HP:0100710)2.60736223
25Abnormality of the astrocytes (HP:0100707)2.60582352
26Astrocytoma (HP:0009592)2.60582352
27Agammaglobulinemia (HP:0004432)2.57693651
28Overriding aorta (HP:0002623)2.56267207
29Chromosomal breakage induced by crosslinking agents (HP:0003221)2.54258684
30Turricephaly (HP:0000262)2.53993695
31Small epiphyses (HP:0010585)2.50928060
32Flattened epiphyses (HP:0003071)2.43232197
33Back pain (HP:0003418)2.41597928
34Upper motor neuron abnormality (HP:0002127)2.41310267
35Chronic bronchitis (HP:0004469)2.40521514
36Missing ribs (HP:0000921)2.37093949
37Rectal prolapse (HP:0002035)2.36914672
38Deep palmar crease (HP:0006191)2.33166997
39Broad palm (HP:0001169)2.31350205
40Chronic hepatic failure (HP:0100626)2.29217148
41Chromsome breakage (HP:0040012)2.28677643
42Deep philtrum (HP:0002002)2.27762831
43Pachygyria (HP:0001302)2.27045912
44Hypoplasia of the brainstem (HP:0002365)2.26007844
45Aplasia/Hypoplasia of the brainstem (HP:0007362)2.26007844
46Cubitus valgus (HP:0002967)2.25694527
47Abnormality of cochlea (HP:0000375)2.25370757
48Bronchitis (HP:0012387)2.24243652
49Nasal polyposis (HP:0100582)2.22842334
50Cortical dysplasia (HP:0002539)2.22628487
51Papillary thyroid carcinoma (HP:0002895)2.22239404
52Pendular nystagmus (HP:0012043)2.21301681
53Lissencephaly (HP:0001339)2.20678012
54Congenital glaucoma (HP:0001087)2.20567497
55Bony spicule pigmentary retinopathy (HP:0007737)2.20042642
56Megalocornea (HP:0000485)2.19833534
57Depressed nasal tip (HP:0000437)2.14983254
5811 pairs of ribs (HP:0000878)2.13891720
59Recurrent bronchitis (HP:0002837)2.13391744
60Type II lissencephaly (HP:0007260)2.09163197
61Polymicrogyria (HP:0002126)2.08880579
62Obsessive-compulsive behavior (HP:0000722)2.07831357
63Viral hepatitis (HP:0006562)2.07530897
64Bundle branch block (HP:0011710)2.07320733
65Germ cell neoplasia (HP:0100728)2.05588330
66Bicuspid aortic valve (HP:0001647)2.04950041
67Increased nuchal translucency (HP:0010880)2.00572732
68Abnormality of DNA repair (HP:0003254)1.99899332
69Enlarged kidneys (HP:0000105)1.99808511
70Abolished electroretinogram (ERG) (HP:0000550)1.99686489
71Recurrent otitis media (HP:0000403)1.97093986
72High anterior hairline (HP:0009890)1.96329148
73Abnormality of the diencephalon (HP:0010662)1.95945956
74Hypoplastic pelvis (HP:0008839)1.94940252
75Basal cell carcinoma (HP:0002671)1.94684301
76Bowel incontinence (HP:0002607)1.93714734
77Vertebral clefting (HP:0008428)1.92788946
78Abnormality of the intervertebral disk (HP:0005108)1.92624783
79Neoplasm of the liver (HP:0002896)1.92576953
80Stomach cancer (HP:0012126)1.92575175
81Diastasis recti (HP:0001540)1.91777798
82Abnormality of the distal phalanx of the thumb (HP:0009617)1.91114192
83Nephroblastoma (Wilms tumor) (HP:0002667)1.90483773
84Hepatoblastoma (HP:0002884)1.89620395
85Poikiloderma (HP:0001029)1.88663923
86Glioma (HP:0009733)1.86886222
87Proximal placement of thumb (HP:0009623)1.86248036
88Abnormal number of incisors (HP:0011064)1.85683898
89Truncal obesity (HP:0001956)1.85471402
90Cutis marmorata (HP:0000965)1.85386990
91Sacral dimple (HP:0000960)1.85050073
92Flat cornea (HP:0007720)1.84385131
93Uterine leiomyosarcoma (HP:0002891)1.84011821
94Leiomyosarcoma (HP:0100243)1.84011821
95Aplasia/Hypoplasia of the sternum (HP:0006714)1.83483933
96Abnormality of the anterior chamber (HP:0000593)1.82921619
97Meningocele (HP:0002435)1.82029392
98Optic nerve coloboma (HP:0000588)1.82027297
99Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.81967931
100Deviation of the thumb (HP:0009603)1.81931269
101Absent/shortened dynein arms (HP:0200106)1.80792173
102Dynein arm defect of respiratory motile cilia (HP:0012255)1.80792173
103Wide intermamillary distance (HP:0006610)1.80281182
104Bell-shaped thorax (HP:0001591)1.80263727
105Lymphangioma (HP:0100764)1.79756587
106Abnormality of lateral ventricle (HP:0030047)1.79714035
107Abnormality of the prostate (HP:0008775)1.78890109
108Cellulitis (HP:0100658)1.77864612
109Facial hemangioma (HP:0000329)1.77544775
110Reticulocytosis (HP:0001923)1.77320067
111Rhinitis (HP:0012384)1.77057315
112Abnormal large intestine physiology (HP:0012700)1.76592952
113Spina bifida occulta (HP:0003298)1.76526837
114Abnormal respiratory motile cilium physiology (HP:0012261)1.76268500
115Abnormality of the lower motor neuron (HP:0002366)1.74127779
116Abnormality of the labia majora (HP:0012881)1.74034549
117Trigonocephaly (HP:0000243)1.73045016
118Abnormality of the right ventricle (HP:0001707)1.72387210
119Amyotrophic lateral sclerosis (HP:0007354)1.70614926
120Thin bony cortex (HP:0002753)1.70149365
121Midline defect of the nose (HP:0004122)1.68804692
122Bifid tongue (HP:0010297)1.68330127
123Patellar dislocation (HP:0002999)1.67427906
124Hypoplastic labia majora (HP:0000059)1.66777264
125Hypochromic microcytic anemia (HP:0004840)1.66410276
126Hepatocellular carcinoma (HP:0001402)1.66301433
127Neoplasm of the oral cavity (HP:0100649)1.66084914
128Embryonal renal neoplasm (HP:0011794)1.66073647
129Long toe (HP:0010511)1.65937760
130Abnormality of the fingertips (HP:0001211)1.65934296
131Neonatal hypoglycemia (HP:0001998)1.65877852
132Abnormal pancreas size (HP:0012094)1.65592149
133Insomnia (HP:0100785)1.65225587
134Agnosia (HP:0010524)1.64815352
135Abnormality of reticulocytes (HP:0004312)1.62914733
136Gastrointestinal carcinoma (HP:0002672)1.62213798
137Malignant gastrointestinal tract tumors (HP:0006749)1.62213798
138Sandal gap (HP:0001852)1.62205609
139Abnormality of the corticospinal tract (HP:0002492)1.62201835
140Gastrointestinal stroma tumor (HP:0100723)1.62064698
141Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.62005394
142Macroorchidism (HP:0000053)1.61952099
143Recurrent sinusitis (HP:0011108)1.61857771
144Volvulus (HP:0002580)1.61658892
145Limited elbow extension (HP:0001377)1.60574129
146Attention deficit hyperactivity disorder (HP:0007018)1.60440478
147Thick eyebrow (HP:0000574)1.60171135
148Pointed chin (HP:0000307)1.60002141
149Long eyelashes (HP:0000527)1.59929713
150Ectopic kidney (HP:0000086)1.59732546
151Septate vagina (HP:0001153)1.58597656
152Curly hair (HP:0002212)1.58409238
153Pseudobulbar signs (HP:0002200)1.58075679
154Neoplasm of the adrenal cortex (HP:0100641)1.57831451
155Flat acetabular roof (HP:0003180)1.57597643
156Large earlobe (HP:0009748)1.57047967
157Thin ribs (HP:0000883)1.56819065
158Neoplasm of striated muscle (HP:0009728)1.56531731
159Intellectual disability, profound (HP:0002187)1.56403252
160Abnormality of the carotid arteries (HP:0005344)1.56330547
161Acute lymphatic leukemia (HP:0006721)1.56003404
162Thrombocytosis (HP:0001894)1.55090465
163Squamous cell carcinoma (HP:0002860)1.53911947
164Broad distal phalanx of finger (HP:0009836)1.53905912
165Self-mutilation (HP:0000742)1.52876545
166Abnormal biliary tract physiology (HP:0012439)1.52640061
167Bile duct proliferation (HP:0001408)1.52640061
168Disinhibition (HP:0000734)1.52321159
169Duplication of thumb phalanx (HP:0009942)1.50695846
170Abnormality of the aortic arch (HP:0012303)1.50663639
171Abnormal lung lobation (HP:0002101)1.50149632
172Increased number of teeth (HP:0011069)1.49943461
173Cafe-au-lait spot (HP:0000957)1.49818303
174Hypoplasia of the maxilla (HP:0000327)1.49467579
175Dislocated radial head (HP:0003083)1.48613006
176Hypospadias (HP:0000047)1.47841123

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K105.28506885
2PIK3CG4.04314549
3LMTK23.57849939
4EEF2K3.09113197
5SIK22.78180418
6EPHA32.74011510
7SIK32.52790674
8CDK122.34946704
9PRPF4B2.30798215
10BRD42.28323058
11ERN12.24019773
12SIK12.23308063
13MARK12.21127296
14NEK22.19218221
15TYRO32.09187525
16DYRK32.03795376
17TRIB32.02914271
18ICK1.92234309
19MAPK151.78761278
20KIT1.74532665
21PNCK1.72988247
22KSR11.48202382
23WEE11.38878372
24CDC71.37285251
25FLT31.36939107
26AKT31.36845183
27SMG11.36313106
28RIPK11.31774818
29MAP3K91.31114599
30CAMK1G1.27132545
31CSF1R1.27024288
32ACVR1B1.26793376
33DYRK21.26240791
34CAMK1D1.26149388
35ERBB21.22504253
36SRPK11.21436242
37TYK21.20291841
38MAP3K61.18502087
39PASK1.17767880
40STK31.16217639
41KSR21.15155377
42RPS6KA21.14980903
43TTK1.13549167
44ERBB31.11250885
45PDK31.10719248
46PDK41.10719248
47ATR1.05236773
48NTRK21.03795827
49CDK91.01257703
50STK41.01237122
51DYRK1B1.01095569
52MAP3K41.00627206
53SCYL21.00601891
54BRSK20.99287017
55TGFBR10.98748581
56PKN20.97245990
57FGFR20.96547450
58CDK60.96218142
59RPS6KA40.93944347
60TBK10.93708839
61TNIK0.90108703
62CLK10.87886258
63CDK80.85152325
64MTOR0.84894731
65LATS10.83525223
66PTK60.80682788
67CDK40.80454563
68SGK30.79463205
69WNK10.79422625
70CSNK1A1L0.78986101
71CSNK1G30.76843854
72CASK0.76489082
73CSNK1G10.75455772
74BTK0.75440814
75MELK0.74763011
76CCNB10.73031661
77BRAF0.72779504
78FGFR30.72644410
79RET0.72141375
80TLK10.71983878
81TSSK60.71832570
82DMPK0.69723246
83FGFR40.69209978
84LATS20.69180242
85MATK0.67687813
86HIPK20.67421985
87CHUK0.65962479
88STK38L0.65472686
89BRSK10.65181495
90MKNK20.64201398
91RAF10.63446698
92CHEK20.61296790
93CHEK10.61186012
94PDGFRB0.60754713
95STK380.60247626
96SGK20.59915364
97SYK0.59400713
98PRKD20.59348798
99MARK30.59061743
100MAP3K70.58015229
101YES10.57003133
102PRKAA10.56622826
103GSK3B0.56366164
104AURKA0.55776694
105MKNK10.55140820
106CSNK1G20.54667479
107SGK2230.52059177
108SGK4940.52059177
109RPS6KC10.52016428
110RPS6KL10.52016428
111MAPK40.51970531
112PIM10.51902803
113RPS6KA60.51804244
114PRKCZ0.51372108
115IRAK20.51349806
116MAPK100.51281914
117IRAK40.50239691
118MARK20.49455120
119IKBKE0.48876586
120MAPK140.47943785
121TESK10.47901388
122NEK60.47266103
123MAPK110.46463198
124FRK0.45891536
125PLK10.45638382
126SGK10.45518887
127MAP2K40.45118026
128CDK20.44234094
129MAPK130.43119709
130MAP3K140.43076134
131EPHB20.43016123
132MAP3K80.42170745
133VRK10.42029889
134CDK70.41323162
135AURKB0.41233485
136TAF10.40814663
137JAK10.40164285
138ATM0.39969691
139FGFR10.39826522
140PRKDC0.39400248
141CSNK1E0.39185683
142NTRK10.38166925
143CDK10.38132667
144STK240.38004549
145RPS6KB10.37668179
146RPS6KA10.36938215
147RPS6KB20.35500479
148MAP4K10.34455137
149CSNK1D0.33745371
150PDGFRA0.33207425

Predicted pathways (KEGG)

RankGene SetZ-score
1B cell receptor signaling pathway_Homo sapiens_hsa046622.38209720
2Selenocompound metabolism_Homo sapiens_hsa004502.29180550
3mRNA surveillance pathway_Homo sapiens_hsa030152.12228331
4Chronic myeloid leukemia_Homo sapiens_hsa052202.05951572
5Endometrial cancer_Homo sapiens_hsa052131.96467305
6Primary bile acid biosynthesis_Homo sapiens_hsa001201.84769625
7Systemic lupus erythematosus_Homo sapiens_hsa053221.83012324
8Cell cycle_Homo sapiens_hsa041101.80743451
9Colorectal cancer_Homo sapiens_hsa052101.78291964
10Thyroid cancer_Homo sapiens_hsa052161.75469336
11Steroid biosynthesis_Homo sapiens_hsa001001.70261761
12Lysine degradation_Homo sapiens_hsa003101.68320100
13Insulin resistance_Homo sapiens_hsa049311.62596041
14Carbohydrate digestion and absorption_Homo sapiens_hsa049731.62550720
15Acute myeloid leukemia_Homo sapiens_hsa052211.58590942
16Base excision repair_Homo sapiens_hsa034101.51066719
17Basal cell carcinoma_Homo sapiens_hsa052171.49342034
18Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.48625896
19Non-small cell lung cancer_Homo sapiens_hsa052231.48452216
20Small cell lung cancer_Homo sapiens_hsa052221.48056338
21Prolactin signaling pathway_Homo sapiens_hsa049171.42215459
22Viral carcinogenesis_Homo sapiens_hsa052031.40236629
23Fatty acid degradation_Homo sapiens_hsa000711.34452742
24Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.33127366
25Central carbon metabolism in cancer_Homo sapiens_hsa052301.32866089
26Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.31315013
27Type II diabetes mellitus_Homo sapiens_hsa049301.31273768
28Dorso-ventral axis formation_Homo sapiens_hsa043201.31074727
29Notch signaling pathway_Homo sapiens_hsa043301.29372738
30NF-kappa B signaling pathway_Homo sapiens_hsa040641.28776763
31Adherens junction_Homo sapiens_hsa045201.28643915
32Maturity onset diabetes of the young_Homo sapiens_hsa049501.28277834
33Bladder cancer_Homo sapiens_hsa052191.28136519
34Pancreatic cancer_Homo sapiens_hsa052121.27398739
35Fanconi anemia pathway_Homo sapiens_hsa034601.26515654
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.25018606
37Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.24564147
38TGF-beta signaling pathway_Homo sapiens_hsa043501.23614531
39Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.20885658
40Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.19780761
41Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.19644330
42PPAR signaling pathway_Homo sapiens_hsa033201.17455091
43Measles_Homo sapiens_hsa051621.17422888
44Choline metabolism in cancer_Homo sapiens_hsa052311.16686557
45mTOR signaling pathway_Homo sapiens_hsa041501.16513581
46Herpes simplex infection_Homo sapiens_hsa051681.15987749
47Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.11275533
48MicroRNAs in cancer_Homo sapiens_hsa052061.09826090
49One carbon pool by folate_Homo sapiens_hsa006701.09685292
50Epstein-Barr virus infection_Homo sapiens_hsa051691.09504165
51Influenza A_Homo sapiens_hsa051641.09200257
52Hepatitis B_Homo sapiens_hsa051611.07514761
53Spliceosome_Homo sapiens_hsa030401.06619145
54Osteoclast differentiation_Homo sapiens_hsa043801.06039395
55Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.05507865
56AMPK signaling pathway_Homo sapiens_hsa041521.05206946
57Melanoma_Homo sapiens_hsa052181.02839997
58HTLV-I infection_Homo sapiens_hsa051661.02128092
59Longevity regulating pathway - mammal_Homo sapiens_hsa042111.01594625
60RNA transport_Homo sapiens_hsa030131.00215095
61Toll-like receptor signaling pathway_Homo sapiens_hsa046200.99363695
62Prostate cancer_Homo sapiens_hsa052150.99011453
63Basal transcription factors_Homo sapiens_hsa030220.96347495
64Fatty acid metabolism_Homo sapiens_hsa012120.92794815
65Thyroid hormone signaling pathway_Homo sapiens_hsa049190.92620039
66Glioma_Homo sapiens_hsa052140.92531166
67Neurotrophin signaling pathway_Homo sapiens_hsa047220.92101692
68Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.91383288
69Transcriptional misregulation in cancer_Homo sapiens_hsa052020.90780774
70Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.90546314
71Apoptosis_Homo sapiens_hsa042100.89558461
72Circadian rhythm_Homo sapiens_hsa047100.88808247
73Mismatch repair_Homo sapiens_hsa034300.88707406
74Alcoholism_Homo sapiens_hsa050340.88283973
75Toxoplasmosis_Homo sapiens_hsa051450.86310384
76Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.85125793
77T cell receptor signaling pathway_Homo sapiens_hsa046600.84977136
78Wnt signaling pathway_Homo sapiens_hsa043100.84378758
79Viral myocarditis_Homo sapiens_hsa054160.84263303
80Complement and coagulation cascades_Homo sapiens_hsa046100.83728635
81Renal cell carcinoma_Homo sapiens_hsa052110.83329978
82Nucleotide excision repair_Homo sapiens_hsa034200.83276311
83Inositol phosphate metabolism_Homo sapiens_hsa005620.81458111
84Insulin signaling pathway_Homo sapiens_hsa049100.81443462
85Fatty acid biosynthesis_Homo sapiens_hsa000610.80566506
86Pentose phosphate pathway_Homo sapiens_hsa000300.78742574
87Glucagon signaling pathway_Homo sapiens_hsa049220.78067844
88Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77513016
89DNA replication_Homo sapiens_hsa030300.77062298
90MAPK signaling pathway_Homo sapiens_hsa040100.75590399
91Gap junction_Homo sapiens_hsa045400.74521490
92Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74368786
93Antigen processing and presentation_Homo sapiens_hsa046120.74032895
94Primary immunodeficiency_Homo sapiens_hsa053400.73648627
95N-Glycan biosynthesis_Homo sapiens_hsa005100.73260471
96Hedgehog signaling pathway_Homo sapiens_hsa043400.71708588
97FoxO signaling pathway_Homo sapiens_hsa040680.70526673
98TNF signaling pathway_Homo sapiens_hsa046680.68138425
99Sulfur relay system_Homo sapiens_hsa041220.67861486
100ErbB signaling pathway_Homo sapiens_hsa040120.67789519
101Staphylococcus aureus infection_Homo sapiens_hsa051500.67351328
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.66477553
103Prion diseases_Homo sapiens_hsa050200.65088242
104Phenylalanine metabolism_Homo sapiens_hsa003600.64285944
105Proteoglycans in cancer_Homo sapiens_hsa052050.63989089
106Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.62894467
107Legionellosis_Homo sapiens_hsa051340.62791383
108Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61971643
109Phospholipase D signaling pathway_Homo sapiens_hsa040720.61104908
110Hepatitis C_Homo sapiens_hsa051600.60358162
111Jak-STAT signaling pathway_Homo sapiens_hsa046300.58930563
112VEGF signaling pathway_Homo sapiens_hsa043700.57854432
113Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.57803234
114Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57694489
115Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57573399
116Glycosaminoglycan degradation_Homo sapiens_hsa005310.56394814
117AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.55031211
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.54599301
119p53 signaling pathway_Homo sapiens_hsa041150.54571967
120Hippo signaling pathway_Homo sapiens_hsa043900.54435509
121Melanogenesis_Homo sapiens_hsa049160.54019311
122Axon guidance_Homo sapiens_hsa043600.53406459
123Leishmaniasis_Homo sapiens_hsa051400.53060124
124HIF-1 signaling pathway_Homo sapiens_hsa040660.52493702
125Pathways in cancer_Homo sapiens_hsa052000.51667658
126Estrogen signaling pathway_Homo sapiens_hsa049150.49739272
127Adipocytokine signaling pathway_Homo sapiens_hsa049200.48314515
128Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.48236724
129Butanoate metabolism_Homo sapiens_hsa006500.48101751
130Biosynthesis of amino acids_Homo sapiens_hsa012300.47221604
131Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.46328724
132Oocyte meiosis_Homo sapiens_hsa041140.46169515
133GnRH signaling pathway_Homo sapiens_hsa049120.45472163
134RNA degradation_Homo sapiens_hsa030180.44388625
135Bile secretion_Homo sapiens_hsa049760.43868502
136Sphingolipid signaling pathway_Homo sapiens_hsa040710.41152121
137Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.41123978
138Non-homologous end-joining_Homo sapiens_hsa034500.40534969

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