ZBTB7A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)3.54226934
2mannose metabolic process (GO:0006013)3.28867557
3glutamate secretion (GO:0014047)3.25870193
4synaptic vesicle exocytosis (GO:0016079)3.25349454
5negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.08108752
6positive regulation of protein dephosphorylation (GO:0035307)2.81065829
7positive regulation of Cdc42 GTPase activity (GO:0043089)2.80423794
8signal complex assembly (GO:0007172)2.78377842
9modulation by symbiont of host cellular process (GO:0044068)2.78130181
10negative regulation of erythrocyte differentiation (GO:0045647)2.77413409
11modulation by virus of host process (GO:0019054)2.75772727
12antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.75188159
13antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.75188159
14positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.75002640
15antigen processing and presentation of endogenous antigen (GO:0019883)2.74568569
16desmosome organization (GO:0002934)2.72806485
17JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.69976758
18modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.62934535
19positive regulation by organism of defense response of other organism involved in symbiotic interact2.62934535
20modulation by symbiont of host immune response (GO:0052553)2.62934535
21positive regulation by symbiont of host defense response (GO:0052509)2.62934535
22modulation by symbiont of host defense response (GO:0052031)2.62934535
23modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.62934535
24regulation of T-helper 2 cell differentiation (GO:0045628)2.62448740
25regulation of early endosome to late endosome transport (GO:2000641)2.61961165
26positive regulation of synapse maturation (GO:0090129)2.59248829
27regulation of cholesterol storage (GO:0010885)2.56917173
28peptidyl-tyrosine autophosphorylation (GO:0038083)2.56246564
29interleukin-1-mediated signaling pathway (GO:0070498)2.54108679
30positive regulation of fatty acid beta-oxidation (GO:0032000)2.53412657
31regulation of extracellular matrix disassembly (GO:0010715)2.52143914
32activation of MAPKKK activity (GO:0000185)2.48271742
33activation of Rac GTPase activity (GO:0032863)2.47633026
34oxygen transport (GO:0015671)2.47521762
35cerebellar granule cell differentiation (GO:0021707)2.46000278
36negative regulation of cell killing (GO:0031342)2.44327808
37negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.44327808
38positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.43894786
39sodium ion export (GO:0071436)2.43443654
40response to laminar fluid shear stress (GO:0034616)2.40861807
41positive regulation of receptor recycling (GO:0001921)2.40783022
42positive regulation of gamma-delta T cell activation (GO:0046645)2.38239289
43detection of bacterium (GO:0016045)2.38119650
44gas transport (GO:0015669)2.37851768
45regulation of apoptotic process involved in morphogenesis (GO:1902337)2.36705721
46cytoskeletal anchoring at plasma membrane (GO:0007016)2.36569232
47macrophage activation involved in immune response (GO:0002281)2.35939022
48detection of other organism (GO:0098543)2.35920648
49negative regulation of fatty acid transport (GO:2000192)2.33515508
50positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.33131039
51lipopolysaccharide-mediated signaling pathway (GO:0031663)2.33017508
52barbed-end actin filament capping (GO:0051016)2.32969406
53antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.32756892
54regulation of interferon-beta biosynthetic process (GO:0045357)2.30783437
55positive regulation of interferon-alpha production (GO:0032727)2.29851593
56negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.29438887
57stress fiber assembly (GO:0043149)2.29376739
58regulation of necrotic cell death (GO:0010939)2.28257901
59endothelial cell chemotaxis (GO:0035767)2.26704590
60protein targeting to plasma membrane (GO:0072661)2.26704152
61immunoglobulin mediated immune response (GO:0016064)2.25711630
62positive regulation of extracellular matrix organization (GO:1903055)2.25704663
63L-amino acid import (GO:0043092)2.25264090
64bundle of His cell to Purkinje myocyte communication (GO:0086069)2.25199088
65hemidesmosome assembly (GO:0031581)2.23591078
66adenosine receptor signaling pathway (GO:0001973)2.23427394
67regulation of regulated secretory pathway (GO:1903305)2.21545861
68focal adhesion assembly (GO:0048041)2.19910322
69cell-substrate adherens junction assembly (GO:0007045)2.19910322
70adherens junction assembly (GO:0034333)2.19548996
71semaphorin-plexin signaling pathway (GO:0071526)2.19406079
72regulation of interferon-alpha production (GO:0032647)2.18965385
73myelin maintenance (GO:0043217)2.18856908
74regulation of extracellular matrix organization (GO:1903053)2.18562082
75negative regulation of homotypic cell-cell adhesion (GO:0034111)2.17292125
76regulation of protein dephosphorylation (GO:0035304)2.17058941
77regulation of leukocyte degranulation (GO:0043300)2.16642740
78regulation of ARF protein signal transduction (GO:0032012)2.16274380
79cell-substrate junction assembly (GO:0007044)2.14815964
80response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.14777892
81response to host (GO:0075136)2.14777892
82response to host defenses (GO:0052200)2.14777892
83interferon-gamma-mediated signaling pathway (GO:0060333)2.14644294
84synaptic vesicle maturation (GO:0016188)2.14324836
85response to type I interferon (GO:0034340)2.13381952
86myeloid dendritic cell differentiation (GO:0043011)2.13267685
87positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.11912714
88response to muramyl dipeptide (GO:0032495)2.11610627
89actin filament polymerization (GO:0030041)2.11191496
90activation of JUN kinase activity (GO:0007257)2.09823785
91positive regulation of cellular amide metabolic process (GO:0034250)2.08276076
92cellular response to thyroid hormone stimulus (GO:0097067)2.07873162
93regulation of synaptic vesicle exocytosis (GO:2000300)2.07788203
94regulation of Rap GTPase activity (GO:0032317)2.07183240
95type I interferon signaling pathway (GO:0060337)2.07151540
96cellular response to type I interferon (GO:0071357)2.07151540
97protein localization to endosome (GO:0036010)2.06294150
98detection of external biotic stimulus (GO:0098581)2.06003611
99modulation by virus of host morphology or physiology (GO:0019048)2.05892836
100cortical actin cytoskeleton organization (GO:0030866)2.05482692
101positive regulation of antigen processing and presentation (GO:0002579)2.04389036
102regulation of cholesterol homeostasis (GO:2000188)2.04209070
103lymphocyte chemotaxis (GO:0048247)2.04175119
104positive thymic T cell selection (GO:0045059)2.04163031
105cellular response to virus (GO:0098586)2.04010452
106regulation of ARF GTPase activity (GO:0032312)2.03347184
107regulation of B cell receptor signaling pathway (GO:0050855)2.03206393
108mature B cell differentiation (GO:0002335)2.02696754
109positive regulation of type 2 immune response (GO:0002830)2.01959452
110vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.00394300
111positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.00127368
112negative regulation of macrophage derived foam cell differentiation (GO:0010745)1.99732194
113negative regulation of calcium ion transport into cytosol (GO:0010523)1.99704004
114myeloid dendritic cell activation (GO:0001773)1.98522277
115regulation of interleukin-12 biosynthetic process (GO:0045075)1.98388781
116megakaryocyte development (GO:0035855)1.97686061
117germinal center formation (GO:0002467)1.97628414
118cellular potassium ion homeostasis (GO:0030007)1.97255554
119positive regulation of histone deacetylation (GO:0031065)1.96847633
120positive regulation of cholesterol efflux (GO:0010875)1.96044783
121regulation of type 2 immune response (GO:0002828)1.95414650
122negative regulation of type 2 immune response (GO:0002829)1.95269886
123B cell receptor signaling pathway (GO:0050853)1.94423570
124apoptotic cell clearance (GO:0043277)1.93452330
125negative regulation of amyloid precursor protein catabolic process (GO:1902992)1.92926802
126response to peptidoglycan (GO:0032494)1.92671091
127negative regulation of interleukin-8 production (GO:0032717)1.92450083
128negative regulation of T-helper cell differentiation (GO:0045623)1.91575903
129negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)1.91575903
130myeloid cell activation involved in immune response (GO:0002275)1.90672049
131hydrogen peroxide biosynthetic process (GO:0050665)1.89655477
132tolerance induction (GO:0002507)1.89390932
133negative regulation of toll-like receptor signaling pathway (GO:0034122)1.88559795
134CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)1.87808838
135G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)1.87511068
136leukocyte aggregation (GO:0070486)1.82282171
137thymic T cell selection (GO:0045061)1.81755922
138granulocyte activation (GO:0036230)1.81211741
139myeloid cell development (GO:0061515)1.81030583
140endoplasmic reticulum calcium ion homeostasis (GO:0032469)1.78414536
141regulation of gamma-delta T cell differentiation (GO:0045586)1.77541063
142regulation of gamma-delta T cell activation (GO:0046643)1.77493783
143positive regulation of excitatory postsynaptic membrane potential (GO:2000463)1.77336760
144regulation of dendritic cell antigen processing and presentation (GO:0002604)1.77187006
145regulation of antigen processing and presentation (GO:0002577)1.76193203
146G-protein coupled purinergic receptor signaling pathway (GO:0035588)1.75966594
147negative regulation of lipid storage (GO:0010888)1.75857204
148respiratory burst (GO:0045730)1.75371537
149neutrophil activation involved in immune response (GO:0002283)1.75252514
150regulation of T cell tolerance induction (GO:0002664)1.75112147
151neutrophil activation (GO:0042119)1.75001247
152regulation of antigen processing and presentation of peptide antigen (GO:0002583)1.74801879
153lymphocyte migration (GO:0072676)1.73948099
154positive regulation of Rap GTPase activity (GO:0032854)1.73642717
155leukocyte cell-cell adhesion (GO:0007159)1.73077378
156response to host immune response (GO:0052572)1.72745854
157response to immune response of other organism involved in symbiotic interaction (GO:0052564)1.72745854
158neuronal action potential propagation (GO:0019227)1.72012177
159regulation of cellular amide metabolic process (GO:0034248)1.72006969
160response to fungus (GO:0009620)1.71988472
161positive regulation of interferon-gamma biosynthetic process (GO:0045078)1.71315739

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human3.30178750
2IRF8_22096565_ChIP-ChIP_GC-B_Human2.63040991
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.58313121
4THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.25396400
5BP1_19119308_ChIP-ChIP_Hs578T_Human2.19266994
6VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.17916712
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.17430839
8STAT6_21828071_ChIP-Seq_BEAS2B_Human2.16607783
9* MYC_22102868_ChIP-Seq_BL_Human1.93990536
10KDM2B_26808549_Chip-Seq_SUP-B15_Human1.93832238
11FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.87018407
12* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.86517882
13TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.82133903
14IKZF1_21737484_ChIP-ChIP_HCT116_Human1.79458442
15IRF8_21731497_ChIP-ChIP_J774_Mouse1.77781536
16IRF8_27001747_Chip-Seq_BMDM_Mouse1.74590838
17TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72501249
18RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.67706481
19NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.67379083
20ERG_21242973_ChIP-ChIP_JURKAT_Human1.65745609
21GATA1_19941826_ChIP-Seq_K562_Human1.65129101
22* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.63655324
23Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.60705973
24* KDM2B_26808549_Chip-Seq_DND41_Human1.59824998
25* LXR_22292898_ChIP-Seq_THP-1_Human1.58897138
26* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.58595754
27SCL_19346495_ChIP-Seq_HPC-7_Human1.57222738
28* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.56069966
29TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.55794115
30ESR2_21235772_ChIP-Seq_MCF-7_Human1.54851229
31* RUNX_20019798_ChIP-Seq_JUKART_Human1.53880148
32* TCF7_22412390_ChIP-Seq_EML_Mouse1.53877259
33* P68_20966046_ChIP-Seq_HELA_Human1.52900371
34UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.52798946
35STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.52461475
36* VDR_24763502_ChIP-Seq_THP-1_Human1.51931929
37GATA1_19941827_ChIP-Seq_MEL_Mouse1.49864391
38CDX2_20551321_ChIP-Seq_CACO-2_Human1.49488181
39MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.49356415
40SPI1_23127762_ChIP-Seq_K562_Human1.48682951
41SRY_22984422_ChIP-ChIP_TESTIS_Rat1.48663170
42SA1_27219007_Chip-Seq_ERYTHROID_Human1.48219570
43SMC4_20622854_ChIP-Seq_HELA_Human1.47819788
44* KDM2B_26808549_Chip-Seq_K562_Human1.47818276
45SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.43044139
46MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.42046607
47GATA2_21666600_ChIP-Seq_HMVEC_Human1.40891408
48* VDR_21846776_ChIP-Seq_THP-1_Human1.40152128
49MYB_21317192_ChIP-Seq_ERMYB_Mouse1.39500888
50* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.39290597
51GATA2_19941826_ChIP-Seq_K562_Human1.38912089
52DROSHA_22980978_ChIP-Seq_HELA_Human1.35384565
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.35028546
54TET1_21451524_ChIP-Seq_MESCs_Mouse1.34829810
55ELK3_25401928_ChIP-Seq_HUVEC_Human1.33166514
56* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.31009021
57* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.30585566
58GATA1_22025678_ChIP-Seq_K562_Human1.29766515
59ESR1_21235772_ChIP-Seq_MCF-7_Human1.29294049
60SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.29199193
61MAF_26560356_Chip-Seq_TH1_Human1.29094088
62* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28321570
63* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.27864030
64* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.27287936
65CTCF_27219007_Chip-Seq_Bcells_Human1.26587812
66* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.25993632
67E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.25811328
68RARG_19884340_ChIP-ChIP_MEFs_Mouse1.23905577
69TRIM28_21343339_ChIP-Seq_HEK293_Human1.23863676
70* VDR_24787735_ChIP-Seq_THP-1_Human1.23484267
71RACK7_27058665_Chip-Seq_MCF-7_Human1.23255422
72ZNF263_19887448_ChIP-Seq_K562_Human1.22845584
73SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21586257
74* MAF_26560356_Chip-Seq_TH2_Human1.21133461
75MTF2_20144788_ChIP-Seq_MESCs_Mouse1.20704982
76* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.20084137
77SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.18988274
78* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.18756055
79P300_27058665_Chip-Seq_ZR-75-30cells_Human1.18057672
80BCOR_27268052_Chip-Seq_Bcells_Human1.17868203
81DNAJC2_21179169_ChIP-ChIP_NT2_Human1.17509288
82KDM2B_26808549_Chip-Seq_JURKAT_Human1.17276487
83EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.17031799
84FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.16860577
85BRD4_27068464_Chip-Seq_AML-cells_Mouse1.13434383
86RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.09300358
87NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.08773535
88* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.08659906
89TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.06907225
90PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.06823762
91SOX2_20726797_ChIP-Seq_SW620_Human1.06700066
92ELF1_20517297_ChIP-Seq_JURKAT_Human1.06311704
93BCL6_27268052_Chip-Seq_Bcells_Human1.05869276
94SUZ12_27294783_Chip-Seq_ESCs_Mouse1.05624687
95EGR1_19032775_ChIP-ChIP_M12_Human1.05182446
96SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.04718717
97SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.03879533
98ZNF217_24962896_ChIP-Seq_MCF-7_Human1.03773774
99CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.03213103
100* TP63_22573176_ChIP-Seq_HFKS_Human1.02635792
101NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02493666
102EZH2_18974828_ChIP-Seq_MESCs_Mouse1.02418051
103RNF2_18974828_ChIP-Seq_MESCs_Mouse1.02418051
104SMAD_19615063_ChIP-ChIP_OVARY_Human1.01707490
105* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.01431978
106FOXO3_23340844_ChIP-Seq_DLD1_Human1.01361564
107SMC1_22415368_ChIP-Seq_MEFs_Mouse1.00715929
108LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.00580659
109SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.99863148
110SA1_27219007_Chip-Seq_Bcells_Human0.99698138
111* RARB_27405468_Chip-Seq_BRAIN_Mouse0.99687341
112RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.99051467
113BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99019560
114* UTX_26944678_Chip-Seq_JUKART_Human0.98912257
115PPARA_22158963_ChIP-Seq_LIVER_Mouse0.97602905
116MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.97552478
117SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.97476354
118JARID2_20075857_ChIP-Seq_MESCs_Mouse0.97387945
119NCOR1_26117541_ChIP-Seq_K562_Human0.97149349
120* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97087834
121* SOX2_27498859_Chip-Seq_STOMACH_Mouse0.96734674
122RUNX1_22412390_ChIP-Seq_EML_Mouse0.96692077
123TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.96134902
124P63_26484246_Chip-Seq_KERATINOCYTES_Human0.95704281
125* GATA1_22383799_ChIP-Seq_G1ME_Mouse0.95686421
126ATF3_27146783_Chip-Seq_COLON_Human0.95400769
127TET1_21490601_ChIP-Seq_MESCs_Mouse0.95345353
128JARID2_20064375_ChIP-Seq_MESCs_Mouse0.95006065
129ESR1_20079471_ChIP-ChIP_T-47D_Human0.94845130
130PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.93070780
131RUNX1_27514584_Chip-Seq_MCF-7_Human0.92800842
132EZH2_27294783_Chip-Seq_ESCs_Mouse0.90978502
133NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.90448628
134CREB1_26743006_Chip-Seq_LNCaP_Human0.89245470
135KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.88460846
136* CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.87741849
137AR_21572438_ChIP-Seq_LNCaP_Human0.87555938
138SOX9_24532713_ChIP-Seq_HFSC_Mouse0.87555424
139* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.87533802

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation3.36012138
2MP0002822_catalepsy2.68577027
3MP0003300_gastrointestinal_ulcer2.57120411
4MP0003191_abnormal_cellular_cholesterol2.47379332
5MP0004510_myositis2.46194130
6MP0003172_abnormal_lysosome_physiology2.38470133
7MP0005058_abnormal_lysosome_morphology2.35089784
8MP0005387_immune_system_phenotype2.25041126
9MP0001790_abnormal_immune_system2.25041126
10MP0003436_decreased_susceptibility_to2.18090001
11MP0005451_abnormal_body_composition2.09847246
12MP0000685_abnormal_immune_system2.01294604
13MP0010234_abnormal_vibrissa_follicle1.97014249
14MP0005000_abnormal_immune_tolerance1.94803003
15MP0009785_altered_susceptibility_to1.93903474
16MP0003075_altered_response_to1.93788034
17MP0002148_abnormal_hypersensitivity_rea1.91592193
18MP0004947_skin_inflammation1.90766085
19MP0003724_increased_susceptibility_to1.88365266
20MP0004859_abnormal_synaptic_plasticity1.84387293
21MP0003866_abnormal_defecation1.83011387
22MP0005025_abnormal_response_to1.80954544
23MP0005409_darkened_coat_color1.80054246
24MP0001835_abnormal_antigen_presentation1.79269541
25MP0003656_abnormal_erythrocyte_physiolo1.74834996
26MP0005167_abnormal_blood-brain_barrier1.74329205
27MP0002419_abnormal_innate_immunity1.68706057
28MP0005257_abnormal_intraocular_pressure1.67158605
29MP0005310_abnormal_salivary_gland1.66488505
30MP0008260_abnormal_autophagy1.65408742
31MP0010155_abnormal_intestine_physiology1.64483662
32MP0000678_abnormal_parathyroid_gland1.63760897
33MP0001800_abnormal_humoral_immune1.63179813
34MP0003453_abnormal_keratinocyte_physiol1.62263257
35MP0003045_fibrosis1.59348467
36MP0002452_abnormal_antigen_presenting1.57091041
37MP0005464_abnormal_platelet_physiology1.56172322
38MP0002723_abnormal_immune_serum1.53422775
39MP0003879_abnormal_hair_cell1.51946361
40MP0009379_abnormal_foot_pigmentation1.51841410
41MP0002796_impaired_skin_barrier1.44806133
42MP0001819_abnormal_immune_cell1.44520831
43MP0001873_stomach_inflammation1.43505766
44MP0002420_abnormal_adaptive_immunity1.42397216
45MP0005166_decreased_susceptibility_to1.42087770
46MP0009780_abnormal_chondrocyte_physiolo1.39699299
47MP0001849_ear_inflammation1.37423958
48MP0003279_aneurysm1.36248524
49MP0003690_abnormal_glial_cell1.32852438
50* MP0005671_abnormal_response_to1.32126986
51MP0004381_abnormal_hair_follicle1.31130248
52MP0001958_emphysema1.28669453
53MP0004858_abnormal_nervous_system1.27141907
54MP0001533_abnormal_skeleton_physiology1.26620659
55MP0005076_abnormal_cell_differentiation1.25455421
56MP0006082_CNS_inflammation1.24975139
57MP0001348_abnormal_lacrimal_gland1.24071517
58MP0001845_abnormal_inflammatory_respons1.23738957
59MP0003091_abnormal_cell_migration1.21880092
60MP0002166_altered_tumor_susceptibility1.17573435
61MP0008961_abnormal_basal_metabolism1.16781856
62MP0001663_abnormal_digestive_system1.15334091
63MP0002998_abnormal_bone_remodeling1.14651218
64MP0002249_abnormal_larynx_morphology1.14603834
65MP0009840_abnormal_foam_cell1.14170233
66MP0009333_abnormal_splenocyte_physiolog1.12856329
67MP0005023_abnormal_wound_healing1.11783873
68MP0004185_abnormal_adipocyte_glucose1.08971878
69MP0005375_adipose_tissue_phenotype1.08584118
70MP0001501_abnormal_sleep_pattern1.07967648
71MP0000604_amyloidosis1.07247715
72MP0002405_respiratory_system_inflammati1.06665614
73MP0002877_abnormal_melanocyte_morpholog1.06243724
74MP0005083_abnormal_biliary_tract1.05932055
75MP0005666_abnormal_adipose_tissue1.04989263
76MP0008874_decreased_physiological_sensi1.04782715
77MP0001545_abnormal_hematopoietic_system1.04190019
78MP0005397_hematopoietic_system_phenotyp1.04190019
79MP0002138_abnormal_hepatobiliary_system1.03491736
80MP0002254_reproductive_system_inflammat1.03221830
81MP0002060_abnormal_skin_morphology1.02594593
82MP0002909_abnormal_adrenal_gland1.00876635
83MP0002089_abnormal_postnatal_growth/wei1.00489753
84MP0003566_abnormal_cell_adhesion0.99533864
85MP0000858_altered_metastatic_potential0.99453761
86MP0008004_abnormal_stomach_pH0.98223673
87MP0009278_abnormal_bone_marrow0.97258152
88MP0005275_abnormal_skin_tensile0.97145507
89MP0001851_eye_inflammation0.95517844
90MP0001765_abnormal_ion_homeostasis0.94708544
91MP0008469_abnormal_protein_level0.93666745
92MP0009046_muscle_twitch0.93017681
93* MP0000716_abnormal_immune_system0.92942787
94MP0002006_tumorigenesis0.92842524
95MP0000681_abnormal_thyroid_gland0.92713660
96MP0002139_abnormal_hepatobiliary_system0.92602757
97MP0003329_amyloid_beta_deposits0.91820905
98MP0008569_lethality_at_weaning0.91316224
99MP0003705_abnormal_hypodermis_morpholog0.90759793
100MP0003763_abnormal_thymus_physiology0.90676537
101MP0001216_abnormal_epidermal_layer0.89764235
102MP0004130_abnormal_muscle_cell0.89514714
103MP0005390_skeleton_phenotype0.89481169
104* MP0002398_abnormal_bone_marrow0.87927720
105MP0000920_abnormal_myelination0.87781285
106MP0009764_decreased_sensitivity_to0.87432362
107MP0000013_abnormal_adipose_tissue0.86401062
108MP0003635_abnormal_synaptic_transmissio0.84638149
109MP0000343_altered_response_to0.82566925
110MP0005381_digestive/alimentary_phenotyp0.81794232
111MP0005501_abnormal_skin_physiology0.80805588
112MP0004270_analgesia0.80460759
113MP0003828_pulmonary_edema0.80404733
114MP0000003_abnormal_adipose_tissue0.80184046
115MP0008438_abnormal_cutaneous_collagen0.80165116
116MP0002933_joint_inflammation0.79038496
117MP0003633_abnormal_nervous_system0.78226504
118MP0009931_abnormal_skin_appearance0.78020635
119MP0002063_abnormal_learning/memory/cond0.77882946
120MP0002064_seizures0.76602589
121MP0001502_abnormal_circadian_rhythm0.76460317
122MP0003183_abnormal_peptide_metabolism0.75988795
123MP0010771_integument_phenotype0.75592190
124MP0001968_abnormal_touch/_nociception0.75001071
125MP0000465_gastrointestinal_hemorrhage0.74578960
126MP0002733_abnormal_thermal_nociception0.73307464
127MP0001970_abnormal_pain_threshold0.71349054
128MP0003283_abnormal_digestive_organ0.70255187

Predicted human phenotypes

RankGene SetZ-score
1Obstructive sleep apnea (HP:0002870)4.73171455
2Eczematoid dermatitis (HP:0000976)4.17409727
3Pustule (HP:0200039)4.15736156
4Recurrent abscess formation (HP:0002722)3.44000802
5Recurrent bacterial skin infections (HP:0005406)3.08202805
6Right ventricular cardiomyopathy (HP:0011663)3.05612472
7Increased IgE level (HP:0003212)3.02196439
8Neurofibrillary tangles (HP:0002185)2.97452687
9Cerebral inclusion bodies (HP:0100314)2.97032459
10Mediastinal lymphadenopathy (HP:0100721)2.96694903
11Diplopia (HP:0000651)2.87114974
12Abnormality of binocular vision (HP:0011514)2.87114974
13Cellulitis (HP:0100658)2.85544300
14Autoimmune thrombocytopenia (HP:0001973)2.81200502
15Distal lower limb muscle weakness (HP:0009053)2.79190375
16Recurrent gram-negative bacterial infections (HP:0005420)2.70687484
17Dysostosis multiplex (HP:0000943)2.69881557
18Recurrent fungal infections (HP:0002841)2.66302213
19Cheilitis (HP:0100825)2.64480822
20Chronic otitis media (HP:0000389)2.63886328
21Gingivitis (HP:0000230)2.60385812
22Thick nail (HP:0001805)2.58761173
23Prostate neoplasm (HP:0100787)2.54678420
24Broad face (HP:0000283)2.53325643
25Inflammation of the large intestine (HP:0002037)2.52848191
26Plantar hyperkeratosis (HP:0007556)2.51611000
27Abnormality of macrophages (HP:0004311)2.51608527
28Fragile skin (HP:0001030)2.51161589
29Increased connective tissue (HP:0009025)2.50988321
30Hyperacusis (HP:0010780)2.50722284
31Axonal loss (HP:0003447)2.49335602
32Cerebral aneurysm (HP:0004944)2.48423808
33Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.44579551
34Systemic lupus erythematosus (HP:0002725)2.44391596
35Increased cerebral lipofuscin (HP:0011813)2.44018003
36Myokymia (HP:0002411)2.41307190
37Alopecia of scalp (HP:0002293)2.39605256
38Neuronal loss in central nervous system (HP:0002529)2.36219757
39Gastrointestinal inflammation (HP:0004386)2.35017328
40Visual hallucinations (HP:0002367)2.34947906
41Interstitial pulmonary disease (HP:0006530)2.33244751
42Stomatitis (HP:0010280)2.31957648
43Slow saccadic eye movements (HP:0000514)2.31640717
44Milia (HP:0001056)2.30536452
45Recurrent skin infections (HP:0001581)2.29993366
46Petechiae (HP:0000967)2.27860098
47Palmoplantar hyperkeratosis (HP:0000972)2.26446696
48Prolonged bleeding time (HP:0003010)2.26272391
49J-shaped sella turcica (HP:0002680)2.25714891
50Annular pancreas (HP:0001734)2.25681850
51Meningitis (HP:0001287)2.21938977
52Vacuolated lymphocytes (HP:0001922)2.21333802
53Periodontitis (HP:0000704)2.19815999
54Recurrent cutaneous fungal infections (HP:0011370)2.18298393
55Chronic mucocutaneous candidiasis (HP:0002728)2.18298393
56Hypercortisolism (HP:0001578)2.18240042
57Emphysema (HP:0002097)2.16867176
58Urticaria (HP:0001025)2.14109892
59Vasculitis (HP:0002633)2.13314557
60Colitis (HP:0002583)2.12749279
61Myocardial infarction (HP:0001658)2.10613650
62Elevated erythrocyte sedimentation rate (HP:0003565)2.09721866
63Urinary glycosaminoglycan excretion (HP:0003541)2.08686555
64Mucopolysacchariduria (HP:0008155)2.08686555
65Ventricular fibrillation (HP:0001663)2.07548897
66Segmental peripheral demyelination/remyelination (HP:0003481)2.06913713
67Myositis (HP:0100614)2.06748331
68Supranuclear gaze palsy (HP:0000605)2.06205822
69Ankle clonus (HP:0011448)2.04290480
70Protrusio acetabuli (HP:0003179)2.03964220
71Gastrointestinal stroma tumor (HP:0100723)2.03700820
72Recurrent viral infections (HP:0004429)2.03637518
73Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.02876006
74Achilles tendon contracture (HP:0001771)2.02447236
75Thin bony cortex (HP:0002753)2.01835343
76Shallow orbits (HP:0000586)2.01808471
77Insomnia (HP:0100785)2.01497525
78Polygenic inheritance (HP:0010982)2.00528713
79Increased neuronal autofluorescent lipopigment (HP:0002074)1.99544534
80Ventricular tachycardia (HP:0004756)1.98836247
81Obstructive lung disease (HP:0006536)1.98405980
82Chronic obstructive pulmonary disease (HP:0006510)1.98405980
83Lower limb amyotrophy (HP:0007210)1.97873418
84Increased variability in muscle fiber diameter (HP:0003557)1.95595113
85Verrucae (HP:0200043)1.95335772
86Papilloma (HP:0012740)1.95335772
87Palmar hyperkeratosis (HP:0010765)1.95323544
88Poikilocytosis (HP:0004447)1.94774061
89Abnormality of mucopolysaccharide metabolism (HP:0011020)1.94205413
90Abnormality of polysaccharide metabolism (HP:0011012)1.94205413
91Abnormality of glycosaminoglycan metabolism (HP:0004371)1.94205413
92Menorrhagia (HP:0000132)1.93660591
93Atrophic scars (HP:0001075)1.93061802
94Glomerulonephritis (HP:0000099)1.91126412
95Reticulocytosis (HP:0001923)1.88487041
96Upper limb amyotrophy (HP:0009129)1.86235924
97Distal upper limb amyotrophy (HP:0007149)1.86235924
98Sepsis (HP:0100806)1.84848016
99Gingival bleeding (HP:0000225)1.84494308
100Sudden death (HP:0001699)1.84153650
101Focal motor seizures (HP:0011153)1.83988925
102Amyloidosis (HP:0011034)1.83263730
103Action tremor (HP:0002345)1.82004011
104Epistaxis (HP:0000421)1.81495187
105Hyperparathyroidism (HP:0000843)1.80744011
106Abnormality of nail color (HP:0100643)1.80275809
107Abnormality of the Achilles tendon (HP:0005109)1.80203756
108Nasal polyposis (HP:0100582)1.80009914
109Stridor (HP:0010307)1.78276692
110Abnormality of the nasal mucosa (HP:0000433)1.77954904
111Dysmetric saccades (HP:0000641)1.77841177
112Loss of speech (HP:0002371)1.77580076
113Peritonitis (HP:0002586)1.77485322
114Malnutrition (HP:0004395)1.76231796
115Abnormal delayed hypersensitivity skin test (HP:0002963)1.75973355
116Polycythemia (HP:0001901)1.75923046
117Distal lower limb amyotrophy (HP:0008944)1.75845951
118Abnormality of skeletal muscle fiber size (HP:0012084)1.75770505
119Syncope (HP:0001279)1.75656725
120Orchitis (HP:0100796)1.75461369
121Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.75340912
122Dementia (HP:0000726)1.74857242
123Centrally nucleated skeletal muscle fibers (HP:0003687)1.74758660
124Abnormality of small intestinal villus morphology (HP:0011472)1.74180718
125Villous atrophy (HP:0011473)1.74180718
126Cervical subluxation (HP:0003308)1.74063214
127Agitation (HP:0000713)1.74032350
128Rigidity (HP:0002063)1.73890859
129Impaired platelet aggregation (HP:0003540)1.73680484
130Abnormal platelet function (HP:0011869)1.73680484
131Acanthocytosis (HP:0001927)1.71488586
132Agammaglobulinemia (HP:0004432)1.71397255
133Abnormality of liposaccharide metabolism (HP:0010968)1.71331274
134Abnormality of glycosphingolipid metabolism (HP:0004343)1.71331274
135Abnormality of glycolipid metabolism (HP:0010969)1.71331274
136Gastrointestinal infarctions (HP:0005244)1.71219767
137Hyporeflexia of lower limbs (HP:0002600)1.71164253
138Vertebral compression fractures (HP:0002953)1.70211215
139Nuclear cataract (HP:0100018)1.68873102
140Hypergammaglobulinemia (HP:0010702)1.68371903
141Nephritis (HP:0000123)1.68261953
142Mitral regurgitation (HP:0001653)1.66435444
143Mildly elevated creatine phosphokinase (HP:0008180)1.66044076
144Increased serum ferritin (HP:0003281)1.65521762
145Spontaneous hematomas (HP:0007420)1.65250151
146Aneurysm (HP:0002617)1.64633992
147Onion bulb formation (HP:0003383)1.64590789
148Rapidly progressive (HP:0003678)1.63676682
149Global brain atrophy (HP:0002283)1.63656308
150Postural instability (HP:0002172)1.62747405
151Hypochromic anemia (HP:0001931)1.62380887
152Abnormality of the fingertips (HP:0001211)1.62273310
153Bulbar palsy (HP:0001283)1.60832272
154Hemorrhage of the eye (HP:0011885)1.59432384
155Abnormality of the heme biosynthetic pathway (HP:0010472)1.58603821
156Easy fatigability (HP:0003388)1.58195237
157Abnormal blistering of the skin (HP:0008066)1.56650631
158Spinal canal stenosis (HP:0003416)1.56013919
159Ulnar bowing (HP:0003031)1.55231014

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R4.41895810
2RIPK43.07207600
3PIK3CA2.72224404
4MAP3K22.66309164
5ERN12.50461648
6KSR22.33282229
7MAP4K12.26264619
8EPHB11.91972166
9SMG11.82548266
10MAP3K141.73732316
11TAOK31.72248860
12MAP3K11.69485543
13TBK11.65184659
14MAP2K31.61440000
15MAP2K21.58629771
16DMPK1.56213668
17BLK1.56106623
18ICK1.55047817
19IKBKE1.48838989
20TAOK21.48700770
21RIPK11.44518274
22JAK11.43786476
23MAP3K31.41451086
24TAOK11.40627055
25EPHA21.38185092
26TRIB31.34994594
27FES1.34136650
28CDK121.29405071
29CDC42BPA1.23270895
30SIK11.22531446
31WNK11.21178528
32CSK1.15842926
33TYK21.15642871
34MAPK121.15264592
35BMX1.14005533
36IKBKB1.13061589
37SIK21.12888942
38JAK21.09959698
39HIPK21.05740154
40ARAF1.05402636
41TRPM71.02245988
42CAMKK11.02052089
43MAP3K91.00256542
44MET0.99221330
45MAP2K10.98553706
46TTN0.97203293
47RET0.97167190
48RPS6KA20.96954551
49TGFBR20.95966613
50MAP3K130.95635250
51PRKD30.95061060
52MAPK150.94704343
53PIM20.94336552
54MAP3K70.93906959
55IRAK20.93865338
56TESK10.93593768
57HCK0.91448100
58PRKCH0.91391144
59NME20.90534176
60MAP3K110.90383945
61GRK60.89757136
62DAPK20.87063622
63MATK0.85136440
64IRAK40.84865842
65TNK20.84247985
66PTK60.83959731
67PRKD20.83954038
68SYK0.83727361
69NTRK10.81500954
70IRAK30.81323899
71EEF2K0.81086851
72JAK30.80515721
73UHMK10.77752617
74DDR20.77171240
75MAP3K100.75902543
76PRKG20.75744048
77RPS6KL10.75126882
78RPS6KC10.75126882
79MAPK70.75025748
80PDPK10.72532278
81PRPF4B0.71485757
82FGFR30.71325475
83CLK10.70069417
84PDK10.69251184
85MTOR0.68734430
86PDGFRA0.67391848
87CAMKK20.66686344
88FGFR40.66166322
89LATS20.66120055
90PTK20.65987078
91EPHA40.64521174
92ABL20.64317176
93DAPK30.63971199
94FRK0.63591594
95ZAP700.62799566
96MUSK0.62778271
97NTRK30.61018764
98RPS6KA60.60666796
99MAP3K60.60628255
100LCK0.59995901
101GRK50.58427279
102MARK20.57854301
103SGK30.57500632
104CHUK0.56624188
105MAP2K60.56527217
106MAPK40.56389726
107CAMK2D0.55567163
108NME10.55284398
109ITK0.55155029
110MARK30.54919190
111ALK0.54721873
112KIT0.54406783
113SIK30.54374990
114CAMK10.53769070
115TXK0.53755994
116PAK60.52395190
117STK100.52051917
118PRKCQ0.50061089
119BTK0.49980670
120LYN0.49915574
121PRKD10.49717664
122BRAF0.49191281
123DYRK1B0.49165796
124MAPKAPK50.49083032
125PKN20.49059056
126FYN0.48788649
127SGK2230.47692321
128SGK4940.47692321
129GRK70.47177357
130EPHA30.46953152
131CAMK1G0.46871407
132PDGFRB0.46679610
133STK110.46409134
134PTK2B0.45971732
135MAPKAPK30.44259155
136STK380.44052838
137CAMK2B0.43867466
138LRRK20.41960307
139CAMK2G0.41553057

Predicted pathways (KEGG)

RankGene SetZ-score
1Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.92925520
2Leishmaniasis_Homo sapiens_hsa051401.73434422
3Osteoclast differentiation_Homo sapiens_hsa043801.65988220
4Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.65349072
5B cell receptor signaling pathway_Homo sapiens_hsa046621.61673019
6Mineral absorption_Homo sapiens_hsa049781.58280100
7Salivary secretion_Homo sapiens_hsa049701.48721344
8Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.41706559
9Type II diabetes mellitus_Homo sapiens_hsa049301.32668813
10Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.32423671
11Tuberculosis_Homo sapiens_hsa051521.26257173
12Notch signaling pathway_Homo sapiens_hsa043301.24850725
13Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.24597530
14Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.24358862
15Toll-like receptor signaling pathway_Homo sapiens_hsa046201.23739613
16Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20095298
17Prion diseases_Homo sapiens_hsa050201.19497236
18Pertussis_Homo sapiens_hsa051331.18893170
19Salmonella infection_Homo sapiens_hsa051321.18597718
20Staphylococcus aureus infection_Homo sapiens_hsa051501.17669969
21Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.16419060
22Chemokine signaling pathway_Homo sapiens_hsa040621.15547299
23Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.13047814
24Dorso-ventral axis formation_Homo sapiens_hsa043201.12582816
25Renal cell carcinoma_Homo sapiens_hsa052111.10468158
26Gastric acid secretion_Homo sapiens_hsa049711.09363944
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.07622213
28Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.05469281
29Toxoplasmosis_Homo sapiens_hsa051451.02798555
30Acute myeloid leukemia_Homo sapiens_hsa052211.02744193
31Long-term potentiation_Homo sapiens_hsa047201.00793617
32Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97509989
33Insulin secretion_Homo sapiens_hsa049110.97129522
34Platelet activation_Homo sapiens_hsa046110.97013929
35mTOR signaling pathway_Homo sapiens_hsa041500.96467300
36Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.96203657
37NF-kappa B signaling pathway_Homo sapiens_hsa040640.95934935
38Bile secretion_Homo sapiens_hsa049760.95718981
39VEGF signaling pathway_Homo sapiens_hsa043700.95560663
40Pancreatic secretion_Homo sapiens_hsa049720.94685088
41Aldosterone synthesis and secretion_Homo sapiens_hsa049250.94215369
42Synaptic vesicle cycle_Homo sapiens_hsa047210.93054162
43Olfactory transduction_Homo sapiens_hsa047400.92824616
44Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.92664277
45Cholinergic synapse_Homo sapiens_hsa047250.91778408
46NOD-like receptor signaling pathway_Homo sapiens_hsa046210.91747321
47AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.91505470
48Hematopoietic cell lineage_Homo sapiens_hsa046400.90796679
49Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.89448467
50T cell receptor signaling pathway_Homo sapiens_hsa046600.89439049
51Chronic myeloid leukemia_Homo sapiens_hsa052200.89313716
52GnRH signaling pathway_Homo sapiens_hsa049120.89060024
53TNF signaling pathway_Homo sapiens_hsa046680.88712952
54African trypanosomiasis_Homo sapiens_hsa051430.88642947
55Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.88547998
56Glioma_Homo sapiens_hsa052140.88241229
57Amphetamine addiction_Homo sapiens_hsa050310.88205174
58Circadian entrainment_Homo sapiens_hsa047130.86523237
59Insulin signaling pathway_Homo sapiens_hsa049100.85358184
60Glycosaminoglycan degradation_Homo sapiens_hsa005310.84105088
61Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83749675
62Intestinal immune network for IgA production_Homo sapiens_hsa046720.83101172
63Malaria_Homo sapiens_hsa051440.82328052
64Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82318215
65Neurotrophin signaling pathway_Homo sapiens_hsa047220.81039031
66Renin secretion_Homo sapiens_hsa049240.80999737
67Leukocyte transendothelial migration_Homo sapiens_hsa046700.80757706
68Prolactin signaling pathway_Homo sapiens_hsa049170.77820565
69Hepatitis C_Homo sapiens_hsa051600.77549897
70Glutamatergic synapse_Homo sapiens_hsa047240.77382593
71Non-small cell lung cancer_Homo sapiens_hsa052230.77283558
72Amoebiasis_Homo sapiens_hsa051460.76855603
73Bladder cancer_Homo sapiens_hsa052190.76704248
74Oxytocin signaling pathway_Homo sapiens_hsa049210.76078871
75ABC transporters_Homo sapiens_hsa020100.75078429
76Nitrogen metabolism_Homo sapiens_hsa009100.75066668
77Primary immunodeficiency_Homo sapiens_hsa053400.74991509
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.74964104
79Influenza A_Homo sapiens_hsa051640.73616501
80Endometrial cancer_Homo sapiens_hsa052130.73270586
81Longevity regulating pathway - mammal_Homo sapiens_hsa042110.72647409
82Long-term depression_Homo sapiens_hsa047300.71973385
83Rap1 signaling pathway_Homo sapiens_hsa040150.71617028
84Phospholipase D signaling pathway_Homo sapiens_hsa040720.70474108
85Morphine addiction_Homo sapiens_hsa050320.70352901
86Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.70297707
87Lysosome_Homo sapiens_hsa041420.70264647
88Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.69819410
89Sphingolipid signaling pathway_Homo sapiens_hsa040710.69655339
90RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.69433969
91Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.69244527
92Other glycan degradation_Homo sapiens_hsa005110.68590296
93Inositol phosphate metabolism_Homo sapiens_hsa005620.67394233
94Sulfur metabolism_Homo sapiens_hsa009200.66662437
95Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.65963359
96Collecting duct acid secretion_Homo sapiens_hsa049660.65899093
97cAMP signaling pathway_Homo sapiens_hsa040240.65610211
98Shigellosis_Homo sapiens_hsa051310.65593785
99Measles_Homo sapiens_hsa051620.65500521
100Focal adhesion_Homo sapiens_hsa045100.65433061
101Estrogen signaling pathway_Homo sapiens_hsa049150.65423053
102cGMP-PKG signaling pathway_Homo sapiens_hsa040220.64737236
103ErbB signaling pathway_Homo sapiens_hsa040120.64348556
104Endocytosis_Homo sapiens_hsa041440.63456369
105Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.62819782
106Vascular smooth muscle contraction_Homo sapiens_hsa042700.62217600
107Thyroid cancer_Homo sapiens_hsa052160.62050715
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.61036208
109Insulin resistance_Homo sapiens_hsa049310.60976597
110Apoptosis_Homo sapiens_hsa042100.60228234
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.59543098
112Cocaine addiction_Homo sapiens_hsa050300.59345898
113Hepatitis B_Homo sapiens_hsa051610.58843332
114AMPK signaling pathway_Homo sapiens_hsa041520.58837916
115HIF-1 signaling pathway_Homo sapiens_hsa040660.58075246
116Pancreatic cancer_Homo sapiens_hsa052120.57811562
117Choline metabolism in cancer_Homo sapiens_hsa052310.57404695
118Proteoglycans in cancer_Homo sapiens_hsa052050.56826123
119Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.56703591
120Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.56095459
121Calcium signaling pathway_Homo sapiens_hsa040200.54998299
122GABAergic synapse_Homo sapiens_hsa047270.54766085
123MAPK signaling pathway_Homo sapiens_hsa040100.54043633

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