Rank | Gene Set | Z-score |
---|---|---|
1 | axonemal dynein complex assembly (GO:0070286) | 8.16442266 |
2 | glomerular visceral epithelial cell development (GO:0072015) | 8.02926626 |
3 | glomerular epithelial cell development (GO:0072310) | 7.13101309 |
4 | cilium or flagellum-dependent cell motility (GO:0001539) | 6.91372535 |
5 | glomerular basement membrane development (GO:0032836) | 6.90362974 |
6 | cilium movement (GO:0003341) | 5.91216906 |
7 | motile cilium assembly (GO:0044458) | 5.76941925 |
8 | glomerulus development (GO:0032835) | 5.53262890 |
9 | hemidesmosome assembly (GO:0031581) | 5.20679272 |
10 | primary alcohol catabolic process (GO:0034310) | 5.07604138 |
11 | epithelial cilium movement (GO:0003351) | 5.01606583 |
12 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.86905584 |
13 | ethanol metabolic process (GO:0006067) | 4.59774205 |
14 | water homeostasis (GO:0030104) | 4.53020550 |
15 | desmosome organization (GO:0002934) | 4.31822401 |
16 | axoneme assembly (GO:0035082) | 3.98764466 |
17 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.90527994 |
18 | one-carbon compound transport (GO:0019755) | 3.87957100 |
19 | keratinocyte differentiation (GO:0030216) | 3.76722176 |
20 | kidney mesenchyme development (GO:0072074) | 3.69892976 |
21 | establishment of planar polarity (GO:0001736) | 3.68399569 |
22 | establishment of tissue polarity (GO:0007164) | 3.68399569 |
23 | left/right pattern formation (GO:0060972) | 3.67411271 |
24 | metanephric mesenchyme development (GO:0072075) | 3.63513658 |
25 | protein heterotrimerization (GO:0070208) | 3.60786180 |
26 | vitamin transmembrane transport (GO:0035461) | 3.58049403 |
27 | diterpenoid biosynthetic process (GO:0016102) | 3.45703908 |
28 | ethanol oxidation (GO:0006069) | 3.44357023 |
29 | keratinocyte proliferation (GO:0043616) | 3.41267265 |
30 | outer ear morphogenesis (GO:0042473) | 3.37378876 |
31 | positive regulation of p38MAPK cascade (GO:1900745) | 3.36391861 |
32 | lung epithelium development (GO:0060428) | 3.35683801 |
33 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 3.32330700 |
34 | regulation of glomerular filtration (GO:0003093) | 3.24818127 |
35 | sperm capacitation (GO:0048240) | 3.23321566 |
36 | paraxial mesoderm development (GO:0048339) | 3.23227868 |
37 | sodium ion homeostasis (GO:0055078) | 3.21387813 |
38 | epidermal cell differentiation (GO:0009913) | 3.15828124 |
39 | thyroid hormone generation (GO:0006590) | 3.14021789 |
40 | epidermis development (GO:0008544) | 3.11910786 |
41 | microtubule bundle formation (GO:0001578) | 3.05251154 |
42 | lateral sprouting from an epithelium (GO:0060601) | 3.04922957 |
43 | basement membrane organization (GO:0071711) | 3.02697670 |
44 | atrioventricular valve morphogenesis (GO:0003181) | 2.97637199 |
45 | apical protein localization (GO:0045176) | 2.94650677 |
46 | diaphragm development (GO:0060539) | 2.94174170 |
47 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.93429436 |
48 | collagen fibril organization (GO:0030199) | 2.90996014 |
49 | gastrulation with mouth forming second (GO:0001702) | 2.90341040 |
50 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 2.90172024 |
51 | glucocorticoid biosynthetic process (GO:0006704) | 2.88219660 |
52 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.88111157 |
53 | thyroid hormone metabolic process (GO:0042403) | 2.88015691 |
54 | epithelial cell-cell adhesion (GO:0090136) | 2.87061900 |
55 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.86560794 |
56 | skeletal muscle organ development (GO:0060538) | 2.86254543 |
57 | phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) | 2.85059189 |
58 | mesenchymal to epithelial transition (GO:0060231) | 2.84723999 |
59 | positive regulation of mesonephros development (GO:0061213) | 2.84382990 |
60 | regulation of female gonad development (GO:2000194) | 2.83948644 |
61 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.83851183 |
62 | long-chain fatty acid biosynthetic process (GO:0042759) | 2.81013552 |
63 | regulation of water loss via skin (GO:0033561) | 2.80955767 |
64 | regulation of axon guidance (GO:1902667) | 2.79854594 |
65 | retinoic acid metabolic process (GO:0042573) | 2.79832258 |
66 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.79830870 |
67 | epithelial cell differentiation involved in kidney development (GO:0035850) | 2.79210642 |
68 | myoblast fusion (GO:0007520) | 2.78845848 |
69 | establishment of skin barrier (GO:0061436) | 2.78646570 |
70 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.77411964 |
71 | renal system process involved in regulation of blood volume (GO:0001977) | 2.77235932 |
72 | regulation of mesonephros development (GO:0061217) | 2.75776818 |
73 | regulation of p38MAPK cascade (GO:1900744) | 2.74992574 |
74 | intermediate filament organization (GO:0045109) | 2.74979456 |
75 | O-glycan processing (GO:0016266) | 2.74910337 |
76 | positive regulation of digestive system process (GO:0060456) | 2.73839032 |
77 | excretion (GO:0007588) | 2.72914173 |
78 | polarized epithelial cell differentiation (GO:0030859) | 2.72809727 |
79 | primary alcohol metabolic process (GO:0034308) | 2.72135900 |
80 | flavonoid metabolic process (GO:0009812) | 2.69853504 |
81 | positive regulation of catenin import into nucleus (GO:0035413) | 2.69181047 |
82 | regulation of cardioblast differentiation (GO:0051890) | 2.68874189 |
83 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.68394993 |
84 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 2.65628432 |
85 | regulation of cell fate specification (GO:0042659) | 2.64740250 |
86 | cell adhesion mediated by integrin (GO:0033627) | 2.64450770 |
87 | hair cycle (GO:0042633) | 2.61467830 |
88 | molting cycle (GO:0042303) | 2.61467830 |
89 | plasma membrane repair (GO:0001778) | 2.61015447 |
90 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.59199740 |
91 | retinol metabolic process (GO:0042572) | 2.58153042 |
92 | cellular response to vitamin D (GO:0071305) | 2.57597120 |
93 | lipoxygenase pathway (GO:0019372) | 2.57364323 |
94 | hippo signaling (GO:0035329) | 2.57161507 |
95 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.56868161 |
96 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 2.56496912 |
97 | axon extension involved in axon guidance (GO:0048846) | 2.56496912 |
98 | cardiac muscle cell proliferation (GO:0060038) | 2.56221238 |
99 | regulation of glomerulus development (GO:0090192) | 2.56038998 |
100 | body morphogenesis (GO:0010171) | 2.55791908 |
101 | ureteric bud development (GO:0001657) | 2.55577783 |
102 | embryonic camera-type eye development (GO:0031076) | 2.54751350 |
103 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.53813658 |
104 | regulation of male gonad development (GO:2000018) | 2.53805678 |
105 | mesonephric tubule development (GO:0072164) | 2.53681294 |
106 | cochlea development (GO:0090102) | 2.51994813 |
107 | negative regulation of fatty acid transport (GO:2000192) | 2.50437826 |
108 | syncytium formation by plasma membrane fusion (GO:0000768) | 2.50292463 |
109 | mesonephric epithelium development (GO:0072163) | 2.49970938 |
110 | polyol transport (GO:0015791) | 2.48675493 |
111 | interferon-gamma secretion (GO:0072643) | 2.48127577 |
112 | notochord development (GO:0030903) | 2.46422699 |
113 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.45827846 |
114 | positive regulation of kidney development (GO:0090184) | 2.45213980 |
115 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 2.45180163 |
116 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.44798903 |
117 | lymph vessel development (GO:0001945) | 2.44588034 |
118 | keratinization (GO:0031424) | 2.44112918 |
119 | terpenoid biosynthetic process (GO:0016114) | 2.43394400 |
120 | regulation of catenin import into nucleus (GO:0035412) | 2.42687735 |
121 | lung vasculature development (GO:0060426) | 2.42331400 |
122 | head development (GO:0060322) | 2.42091948 |
123 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 2.41220530 |
124 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.40448678 |
125 | positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) | 2.39824957 |
126 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.39199548 |
127 | endocardial cushion morphogenesis (GO:0003203) | 2.39155307 |
128 | skin morphogenesis (GO:0043589) | 2.38841872 |
129 | lymphangiogenesis (GO:0001946) | 2.38221442 |
130 | regulation of branching involved in ureteric bud morphogenesis (GO:0090189) | 2.38146677 |
131 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.38111016 |
132 | ovulation cycle (GO:0042698) | 2.37587069 |
133 | negative regulation of axon guidance (GO:1902668) | 2.37075000 |
134 | renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) | 2.36969074 |
135 | ganglion development (GO:0061548) | 2.36587549 |
136 | sulfate transmembrane transport (GO:1902358) | 2.36505572 |
137 | androgen biosynthetic process (GO:0006702) | 2.36115965 |
138 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.35724098 |
139 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.35437385 |
140 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.35437385 |
141 | regulation of cilium movement (GO:0003352) | 2.34278529 |
142 | syncytium formation (GO:0006949) | 2.34155634 |
143 | organ induction (GO:0001759) | 2.32860215 |
144 | positive regulation of metanephros development (GO:0072216) | 2.32640859 |
145 | intestinal epithelial cell development (GO:0060576) | 2.32168765 |
146 | embryonic body morphogenesis (GO:0010172) | 2.31279927 |
147 | muscle cell fate commitment (GO:0042693) | 2.30047240 |
148 | peptide cross-linking (GO:0018149) | 2.29900108 |
149 | cellular response to gonadotropin stimulus (GO:0071371) | 2.29652518 |
150 | asymmetric protein localization (GO:0008105) | 2.29592405 |
151 | cell-substrate junction assembly (GO:0007044) | 2.29317771 |
152 | negative regulation of catenin import into nucleus (GO:0035414) | 2.28993346 |
153 | regulation of heart morphogenesis (GO:2000826) | 2.28824174 |
154 | skin development (GO:0043588) | 2.28787333 |
155 | keratinocyte development (GO:0003334) | 2.28684607 |
156 | amyloid precursor protein catabolic process (GO:0042987) | 2.27843574 |
157 | proximal/distal pattern formation (GO:0009954) | 2.27828810 |
158 | negative regulation of cell fate specification (GO:0009996) | 2.27644654 |
159 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.27096587 |
160 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.26464465 |
161 | multicellular organismal water homeostasis (GO:0050891) | 2.25613422 |
162 | negative regulation of cell fate commitment (GO:0010454) | 2.25295732 |
163 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 2.24711796 |
164 | regulation of cardioblast proliferation (GO:0003264) | 2.24711796 |
165 | cilium organization (GO:0044782) | 2.24327450 |
166 | camera-type eye morphogenesis (GO:0048593) | 2.23980304 |
167 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 2.23383678 |
168 | regulation of cell proliferation involved in kidney development (GO:1901722) | 2.23215189 |
169 | surfactant homeostasis (GO:0043129) | 2.22110252 |
170 | cilium assembly (GO:0042384) | 2.21469708 |
171 | negative regulation of protein localization to cell surface (GO:2000009) | 2.20795015 |
172 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.20203024 |
173 | establishment of monopolar cell polarity (GO:0061162) | 2.20203024 |
174 | endothelial cell chemotaxis (GO:0035767) | 2.17316411 |
175 | left/right axis specification (GO:0070986) | 2.16844784 |
176 | cellular sodium ion homeostasis (GO:0006883) | 2.15778722 |
177 | cell-cell junction maintenance (GO:0045217) | 2.15652206 |
178 | intermediate filament cytoskeleton organization (GO:0045104) | 2.14167850 |
179 | cell junction maintenance (GO:0034331) | 2.13964262 |
180 | ventricular system development (GO:0021591) | 2.13232624 |
181 | specification of organ identity (GO:0010092) | 2.13099900 |
182 | ear development (GO:0043583) | 2.11314973 |
183 | establishment of apical/basal cell polarity (GO:0035089) | 2.11114189 |
184 | water transport (GO:0006833) | 2.10895804 |
185 | chemical homeostasis within a tissue (GO:0048875) | 2.10256014 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 6.36558571 |
2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 3.53282531 |
3 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.55797442 |
4 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.47914927 |
5 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.16287779 |
6 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.09911963 |
7 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.04582811 |
8 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.99005369 |
9 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.98408376 |
10 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.92299506 |
11 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.92238498 |
12 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.89634498 |
13 | * EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.89483242 |
14 | * RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.89483242 |
15 | * ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.89178303 |
16 | * JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.87692968 |
17 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.86310529 |
18 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.83351855 |
19 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.81322990 |
20 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.80081051 |
21 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.73942328 |
22 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.73128747 |
23 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.72696974 |
24 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.71841311 |
25 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.68356341 |
26 | * TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.67098366 |
27 | * ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.65062929 |
28 | * JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.64416162 |
29 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.57766921 |
30 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.55224835 |
31 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.53831044 |
32 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.52434377 |
33 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.52139846 |
34 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.50990992 |
35 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.49875820 |
36 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.49680515 |
37 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.49414976 |
38 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.46430487 |
39 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.46430487 |
40 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.46430487 |
41 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.46293231 |
42 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.45784407 |
43 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.45748486 |
44 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.44918688 |
45 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.41190813 |
46 | * SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.38667611 |
47 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.35283984 |
48 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.33333126 |
49 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.32958998 |
50 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.31994844 |
51 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.30392717 |
52 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.30123040 |
53 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.26394623 |
54 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.26210862 |
55 | * RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.25937776 |
56 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.25213931 |
57 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.25151450 |
58 | CJUN_26792858_Chip-Seq_BT549_Human | 1.24918015 |
59 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.23933382 |
60 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.22789344 |
61 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.22777009 |
62 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.22753936 |
63 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.21930390 |
64 | KDM2B_26808549_Chip-Seq_K562_Human | 1.21693533 |
65 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.19530339 |
66 | TP53_16413492_ChIP-PET_HCT116_Human | 1.18679919 |
67 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.18370184 |
68 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.18094416 |
69 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.17636306 |
70 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.15151181 |
71 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.15038856 |
72 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.14541834 |
73 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.14396481 |
74 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.12907196 |
75 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12219049 |
76 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.11305011 |
77 | * AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.11144479 |
78 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.10519026 |
79 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.10349242 |
80 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.10169856 |
81 | * NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.10065011 |
82 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.07904914 |
83 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.07892868 |
84 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.07515052 |
85 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.06632514 |
86 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.06450583 |
87 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.06033718 |
88 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.05790127 |
89 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.05664782 |
90 | * RXR_22108803_ChIP-Seq_LS180_Human | 1.03534316 |
91 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.02257886 |
92 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.01335325 |
93 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.01205610 |
94 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.99318022 |
95 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.99197861 |
96 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.98720195 |
97 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.98333140 |
98 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.97880507 |
99 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.97040142 |
100 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.96460713 |
101 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.95559320 |
102 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 0.94925780 |
103 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.94925780 |
104 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.92699409 |
105 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.91858391 |
106 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.91427607 |
107 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.90899722 |
108 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.90879583 |
109 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.90707594 |
110 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.90519552 |
111 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.90015913 |
112 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.89014917 |
113 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.88261329 |
114 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.88137799 |
115 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.88124414 |
116 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.87669406 |
117 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.86919835 |
118 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.86541073 |
119 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.86266936 |
120 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 0.86131853 |
121 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.85201032 |
122 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84073969 |
123 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.83656085 |
124 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.83440914 |
125 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.83168747 |
126 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.83062153 |
127 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.82787219 |
128 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.82635816 |
129 | AR_19668381_ChIP-Seq_PC3_Human | 0.81454900 |
130 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.80766799 |
131 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.80243137 |
132 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 0.79852774 |
133 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.79747655 |
134 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.79421422 |
135 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.79381000 |
136 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.79111596 |
137 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.79026014 |
138 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.78566840 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003941_abnormal_skin_development | 4.58426194 |
2 | MP0004043_abnormal_pH_regulation | 3.75666928 |
3 | MP0004272_abnormal_basement_membrane | 3.50664611 |
4 | MP0005275_abnormal_skin_tensile | 3.13652767 |
5 | MP0002254_reproductive_system_inflammat | 2.86295453 |
6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.73536986 |
7 | MP0003878_abnormal_ear_physiology | 2.70212219 |
8 | MP0005377_hearing/vestibular/ear_phenot | 2.70212219 |
9 | MP0005623_abnormal_meninges_morphology | 2.68087921 |
10 | MP0003705_abnormal_hypodermis_morpholog | 2.64902419 |
11 | MP0000566_synostosis | 2.57366291 |
12 | MP0005503_abnormal_tendon_morphology | 2.55677550 |
13 | MP0000579_abnormal_nail_morphology | 2.47950179 |
14 | MP0009379_abnormal_foot_pigmentation | 2.43591748 |
15 | MP0002796_impaired_skin_barrier | 2.38509517 |
16 | MP0001346_abnormal_lacrimal_gland | 2.27575025 |
17 | MP0000678_abnormal_parathyroid_gland | 2.16652934 |
18 | MP0000467_abnormal_esophagus_morphology | 2.14114441 |
19 | MP0008438_abnormal_cutaneous_collagen | 2.08481023 |
20 | MP0010030_abnormal_orbit_morphology | 2.05129347 |
21 | MP0000762_abnormal_tongue_morphology | 2.00210913 |
22 | MP0001984_abnormal_olfaction | 1.98638553 |
23 | MP0002060_abnormal_skin_morphology | 1.94129879 |
24 | MP0004264_abnormal_extraembryonic_tissu | 1.93725586 |
25 | MP0002249_abnormal_larynx_morphology | 1.92571829 |
26 | MP0003942_abnormal_urinary_system | 1.90913803 |
27 | MP0002653_abnormal_ependyma_morphology | 1.88791592 |
28 | MP0009053_abnormal_anal_canal | 1.85056673 |
29 | MP0000534_abnormal_ureter_morphology | 1.84675272 |
30 | MP0000537_abnormal_urethra_morphology | 1.83899041 |
31 | MP0001849_ear_inflammation | 1.78754163 |
32 | MP0003566_abnormal_cell_adhesion | 1.75695795 |
33 | MP0008004_abnormal_stomach_pH | 1.71638412 |
34 | MP0001765_abnormal_ion_homeostasis | 1.70695075 |
35 | MP0004185_abnormal_adipocyte_glucose | 1.69732649 |
36 | MP0009250_abnormal_appendicular_skeleto | 1.69077085 |
37 | MP0001485_abnormal_pinna_reflex | 1.65960286 |
38 | MP0002233_abnormal_nose_morphology | 1.63497719 |
39 | MP0003385_abnormal_body_wall | 1.63348299 |
40 | MP0005409_darkened_coat_color | 1.61720908 |
41 | MP0002098_abnormal_vibrissa_morphology | 1.61396783 |
42 | MP0010234_abnormal_vibrissa_follicle | 1.61083450 |
43 | MP0002896_abnormal_bone_mineralization | 1.56994936 |
44 | MP0002877_abnormal_melanocyte_morpholog | 1.56651283 |
45 | MP0004782_abnormal_surfactant_physiolog | 1.56356387 |
46 | MP0009384_cardiac_valve_regurgitation | 1.54938383 |
47 | MP0000377_abnormal_hair_follicle | 1.53365275 |
48 | MP0000049_abnormal_middle_ear | 1.49624451 |
49 | MP0002282_abnormal_trachea_morphology | 1.44418195 |
50 | MP0000516_abnormal_urinary_system | 1.43171464 |
51 | MP0005367_renal/urinary_system_phenotyp | 1.43171464 |
52 | MP0005501_abnormal_skin_physiology | 1.37930346 |
53 | MP0005508_abnormal_skeleton_morphology | 1.37291882 |
54 | MP0003937_abnormal_limbs/digits/tail_de | 1.37048493 |
55 | MP0005257_abnormal_intraocular_pressure | 1.36588717 |
56 | MP0000538_abnormal_urinary_bladder | 1.36414218 |
57 | MP0004019_abnormal_vitamin_homeostasis | 1.35512347 |
58 | MP0003119_abnormal_digestive_system | 1.32788079 |
59 | MP0003283_abnormal_digestive_organ | 1.31267839 |
60 | MP0002876_abnormal_thyroid_physiology | 1.28438072 |
61 | MP0002234_abnormal_pharynx_morphology | 1.28053031 |
62 | MP0003755_abnormal_palate_morphology | 1.26929981 |
63 | MP0010368_abnormal_lymphatic_system | 1.26334176 |
64 | MP0005394_taste/olfaction_phenotype | 1.24495022 |
65 | MP0005499_abnormal_olfactory_system | 1.24495022 |
66 | MP0000462_abnormal_digestive_system | 1.23419109 |
67 | MP0000383_abnormal_hair_follicle | 1.19542680 |
68 | MP0003122_maternal_imprinting | 1.19002165 |
69 | MP0003329_amyloid_beta_deposits | 1.17927168 |
70 | MP0000163_abnormal_cartilage_morphology | 1.14016980 |
71 | MP0010678_abnormal_skin_adnexa | 1.13448210 |
72 | MP0009780_abnormal_chondrocyte_physiolo | 1.13137190 |
73 | MP0010386_abnormal_urinary_bladder | 1.12865847 |
74 | MP0002108_abnormal_muscle_morphology | 1.11693742 |
75 | MP0006072_abnormal_retinal_apoptosis | 1.10957299 |
76 | MP0003453_abnormal_keratinocyte_physiol | 1.10891561 |
77 | MP0000465_gastrointestinal_hemorrhage | 1.09301622 |
78 | MP0000613_abnormal_salivary_gland | 1.09293936 |
79 | MP0000681_abnormal_thyroid_gland | 1.08956788 |
80 | MP0001188_hyperpigmentation | 1.07982422 |
81 | MP0005248_abnormal_Harderian_gland | 1.07451282 |
82 | MP0003879_abnormal_hair_cell | 1.07418167 |
83 | MP0010771_integument_phenotype | 1.07044433 |
84 | MP0000751_myopathy | 1.06452291 |
85 | MP0000647_abnormal_sebaceous_gland | 1.06269930 |
86 | MP0002932_abnormal_joint_morphology | 1.05139229 |
87 | MP0002735_abnormal_chemical_nociception | 1.04344592 |
88 | MP0003279_aneurysm | 1.02666421 |
89 | MP0003935_abnormal_craniofacial_develop | 1.01648950 |
90 | MP0001216_abnormal_epidermal_layer | 1.01589715 |
91 | MP0002116_abnormal_craniofacial_bone | 0.99506793 |
92 | MP0001501_abnormal_sleep_pattern | 0.99455602 |
93 | MP0001986_abnormal_taste_sensitivity | 0.97923059 |
94 | MP0000026_abnormal_inner_ear | 0.96936070 |
95 | MP0002132_abnormal_respiratory_system | 0.96290892 |
96 | MP0005083_abnormal_biliary_tract | 0.96234488 |
97 | MP0008789_abnormal_olfactory_epithelium | 0.92466461 |
98 | MP0002697_abnormal_eye_size | 0.91403215 |
99 | MP0003011_delayed_dark_adaptation | 0.91388023 |
100 | MP0002177_abnormal_outer_ear | 0.90671392 |
101 | MP0001756_abnormal_urination | 0.90601213 |
102 | MP0004133_heterotaxia | 0.90327218 |
103 | MP0002295_abnormal_pulmonary_circulatio | 0.90134683 |
104 | MP0000013_abnormal_adipose_tissue | 0.89757364 |
105 | MP0004233_abnormal_muscle_weight | 0.89013752 |
106 | MP0004858_abnormal_nervous_system | 0.88208485 |
107 | MP0004947_skin_inflammation | 0.88041602 |
108 | MP0004885_abnormal_endolymph | 0.87548609 |
109 | MP0005365_abnormal_bile_salt | 0.87314687 |
110 | MP0000427_abnormal_hair_cycle | 0.87053378 |
111 | MP0010352_gastrointestinal_tract_polyps | 0.86801052 |
112 | MP0001879_abnormal_lymphatic_vessel | 0.85603355 |
113 | MP0002115_abnormal_skeleton_extremities | 0.85383176 |
114 | MP0002109_abnormal_limb_morphology | 0.84511243 |
115 | MP0000428_abnormal_craniofacial_morphol | 0.83481897 |
116 | MP0003091_abnormal_cell_migration | 0.82600875 |
117 | MP0001502_abnormal_circadian_rhythm | 0.82452447 |
118 | MP0004859_abnormal_synaptic_plasticity | 0.80843809 |
119 | MP0001299_abnormal_eye_distance/ | 0.80746942 |
120 | MP0002734_abnormal_mechanical_nocicepti | 0.80163558 |
121 | MP0005187_abnormal_penis_morphology | 0.78872754 |
122 | MP0005666_abnormal_adipose_tissue | 0.78537782 |
123 | MP0003045_fibrosis | 0.78230642 |
124 | MP0001664_abnormal_digestion | 0.78196281 |
125 | MP0002837_dystrophic_cardiac_calcinosis | 0.78074720 |
126 | MP0000432_abnormal_head_morphology | 0.75709398 |
127 | MP0002909_abnormal_adrenal_gland | 0.74804831 |
128 | MP0005023_abnormal_wound_healing | 0.73894888 |
129 | MP0004381_abnormal_hair_follicle | 0.73328910 |
130 | MP0002168_other_aberrant_phenotype | 0.72950414 |
131 | MP0003115_abnormal_respiratory_system | 0.72235274 |
132 | MP0005636_abnormal_mineral_homeostasis | 0.71030400 |
133 | MP0005076_abnormal_cell_differentiation | 0.70757894 |
134 | MP0002139_abnormal_hepatobiliary_system | 0.70122407 |
135 | MP0006138_congestive_heart_failure | 0.69774963 |
136 | MP0009931_abnormal_skin_appearance | 0.69698511 |
137 | MP0000470_abnormal_stomach_morphology | 0.69445203 |
138 | MP0001963_abnormal_hearing_physiology | 0.69281560 |
139 | MP0000778_abnormal_nervous_system | 0.68852885 |
140 | MP0008961_abnormal_basal_metabolism | 0.68674412 |
141 | MP0002111_abnormal_tail_morphology | 0.68453096 |
142 | MP0001340_abnormal_eyelid_morphology | 0.68147593 |
143 | MP0002277_abnormal_respiratory_mucosa | 0.66714261 |
144 | MP0002114_abnormal_axial_skeleton | 0.65426635 |
145 | MP0009643_abnormal_urine_homeostasis | 0.65137590 |
146 | MP0003191_abnormal_cellular_cholesterol | 0.64845616 |
147 | MP0003938_abnormal_ear_development | 0.64671743 |
148 | MP0004742_abnormal_vestibular_system | 0.63862986 |
149 | MP0005085_abnormal_gallbladder_physiolo | 0.63059559 |
150 | MP0002822_catalepsy | 0.62784150 |
151 | MP0005646_abnormal_pituitary_gland | 0.62550839 |
152 | MP0000367_abnormal_coat/_hair | 0.62254036 |
153 | MP0002136_abnormal_kidney_physiology | 0.61785004 |
154 | MP0005670_abnormal_white_adipose | 0.57832557 |
155 | MP0002572_abnormal_emotion/affect_behav | 0.55801286 |
156 | MP0005647_abnormal_sex_gland | 0.55046286 |
157 | MP0003890_abnormal_embryonic-extraembry | 0.54052723 |
158 | MP0002089_abnormal_postnatal_growth/wei | 0.53615862 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 7.77105137 |
2 | Abnormal respiratory motile cilium physiology (HP:0012261) | 6.64572532 |
3 | Abnormal respiratory epithelium morphology (HP:0012253) | 6.45176085 |
4 | Abnormal respiratory motile cilium morphology (HP:0005938) | 6.45176085 |
5 | Abnormal ciliary motility (HP:0012262) | 6.34610823 |
6 | Rhinitis (HP:0012384) | 6.31915169 |
7 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 6.15116715 |
8 | Absent/shortened dynein arms (HP:0200106) | 6.15116715 |
9 | Chronic bronchitis (HP:0004469) | 6.00818190 |
10 | Hyperactive renin-angiotensin system (HP:0000841) | 5.48460481 |
11 | Decreased circulating renin level (HP:0003351) | 4.94153414 |
12 | Bronchiectasis (HP:0002110) | 4.41814772 |
13 | Mesangial abnormality (HP:0001966) | 4.29294885 |
14 | Nasal polyposis (HP:0100582) | 4.07379441 |
15 | Right ventricular cardiomyopathy (HP:0011663) | 4.04844133 |
16 | Focal segmental glomerulosclerosis (HP:0000097) | 3.84466220 |
17 | Abnormality of renin-angiotensin system (HP:0000847) | 3.77486259 |
18 | Pterygium (HP:0001059) | 3.76772300 |
19 | Abnormality of the nasal mucosa (HP:0000433) | 3.64606822 |
20 | Popliteal pterygium (HP:0009756) | 3.62293849 |
21 | Hyperaldosteronism (HP:0000859) | 3.61320016 |
22 | Atrophic scars (HP:0001075) | 3.55030549 |
23 | Abnormality of nail color (HP:0100643) | 3.48617262 |
24 | Premature rupture of membranes (HP:0001788) | 3.32253700 |
25 | Fragile nails (HP:0001808) | 3.22428295 |
26 | Lip pit (HP:0100267) | 3.14628694 |
27 | Hyperkalemia (HP:0002153) | 3.11282644 |
28 | Abnormal pancreas size (HP:0012094) | 3.10833766 |
29 | Male infertility (HP:0003251) | 3.10504325 |
30 | Hepatoblastoma (HP:0002884) | 3.05690173 |
31 | Renal salt wasting (HP:0000127) | 3.03586903 |
32 | Protrusio acetabuli (HP:0003179) | 3.03165965 |
33 | Glomerulosclerosis (HP:0000096) | 2.97527850 |
34 | Milia (HP:0001056) | 2.95707342 |
35 | Infertility (HP:0000789) | 2.91329985 |
36 | Fragile skin (HP:0001030) | 2.85353857 |
37 | Abnormality of chloride homeostasis (HP:0011422) | 2.78181219 |
38 | Hypoalbuminemia (HP:0003073) | 2.75780177 |
39 | Abnormal albumin level (HP:0012116) | 2.75780177 |
40 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.75090831 |
41 | Elevated circulating parathyroid hormone (PTH) level (HP:0003165) | 2.75002973 |
42 | Shallow orbits (HP:0000586) | 2.74826379 |
43 | Erythroderma (HP:0001019) | 2.74803517 |
44 | Bronchitis (HP:0012387) | 2.73761195 |
45 | Advanced eruption of teeth (HP:0006288) | 2.72563200 |
46 | Woolly hair (HP:0002224) | 2.71484738 |
47 | Overgrowth (HP:0001548) | 2.71178534 |
48 | Increased IgE level (HP:0003212) | 2.70426422 |
49 | Abnormality of calcium-phosphate metabolism (HP:0100530) | 2.68838324 |
50 | Follicular hyperkeratosis (HP:0007502) | 2.67865551 |
51 | Abnormal hair laboratory examination (HP:0003328) | 2.67657040 |
52 | Bronchomalacia (HP:0002780) | 2.67374678 |
53 | Abnormality of secondary sexual hair (HP:0009888) | 2.66710086 |
54 | Abnormality of the axillary hair (HP:0100134) | 2.66710086 |
55 | Hyponatremia (HP:0002902) | 2.63051532 |
56 | Plantar hyperkeratosis (HP:0007556) | 2.55422904 |
57 | Corneal erosion (HP:0200020) | 2.54612103 |
58 | Aplasia involving bones of the extremities (HP:0009825) | 2.51448773 |
59 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.51448773 |
60 | Aplasia of the phalanges of the hand (HP:0009802) | 2.51448773 |
61 | Abnormality of sodium homeostasis (HP:0010931) | 2.49361596 |
62 | Increased connective tissue (HP:0009025) | 2.47220436 |
63 | Down-sloping shoulders (HP:0200021) | 2.44584805 |
64 | Ankle contracture (HP:0006466) | 2.42508889 |
65 | Morphological abnormality of the middle ear (HP:0008609) | 2.37323123 |
66 | Onycholysis (HP:0001806) | 2.34809600 |
67 | True hermaphroditism (HP:0010459) | 2.34734815 |
68 | Hypotrichosis (HP:0001006) | 2.34585113 |
69 | Recurrent otitis media (HP:0000403) | 2.34216270 |
70 | Abnormality of the dental root (HP:0006486) | 2.31870328 |
71 | Taurodontia (HP:0000679) | 2.31870328 |
72 | Abnormality of permanent molar morphology (HP:0011071) | 2.31870328 |
73 | Oligodontia (HP:0000677) | 2.27826578 |
74 | Germ cell neoplasia (HP:0100728) | 2.26569163 |
75 | Abnormality of dentin (HP:0010299) | 2.23840841 |
76 | Flat acetabular roof (HP:0003180) | 2.23508885 |
77 | Natal tooth (HP:0000695) | 2.19757838 |
78 | Recurrent sinusitis (HP:0011108) | 2.18155532 |
79 | Distal lower limb muscle weakness (HP:0009053) | 2.15495459 |
80 | Adrenal overactivity (HP:0002717) | 2.15080811 |
81 | Alopecia of scalp (HP:0002293) | 2.14355183 |
82 | Type 1 muscle fiber predominance (HP:0003803) | 2.14327290 |
83 | Erythema (HP:0010783) | 2.13750409 |
84 | Abnormality of molar morphology (HP:0011070) | 2.12780226 |
85 | Abnormality of molar (HP:0011077) | 2.12780226 |
86 | Occipital encephalocele (HP:0002085) | 2.10922342 |
87 | Aplasia of the musculature (HP:0100854) | 2.10153850 |
88 | Broad metatarsal (HP:0001783) | 2.08927289 |
89 | Abnormality of the dental pulp (HP:0006479) | 2.08080639 |
90 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.07935917 |
91 | Thin bony cortex (HP:0002753) | 2.07183962 |
92 | Stage 5 chronic kidney disease (HP:0003774) | 2.06311642 |
93 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.05905420 |
94 | Atelectasis (HP:0100750) | 2.05088094 |
95 | Chronic sinusitis (HP:0011109) | 2.04456469 |
96 | Thick nail (HP:0001805) | 2.02610425 |
97 | Abnormality of the salivary glands (HP:0010286) | 2.01760839 |
98 | Fibular aplasia (HP:0002990) | 2.01202194 |
99 | Ridged nail (HP:0001807) | 2.01199798 |
100 | Distal lower limb amyotrophy (HP:0008944) | 2.00635714 |
101 | Coronal craniosynostosis (HP:0004440) | 2.00045229 |
102 | Spinal cord compression (HP:0002176) | 1.99299151 |
103 | Palmoplantar hyperkeratosis (HP:0000972) | 1.98059145 |
104 | Tibial bowing (HP:0002982) | 1.97999657 |
105 | Neonatal short-limb short stature (HP:0008921) | 1.96160914 |
106 | Hyperparathyroidism (HP:0000843) | 1.93936024 |
107 | Tubulointerstitial nephritis (HP:0001970) | 1.93669997 |
108 | Palmar hyperkeratosis (HP:0010765) | 1.93053686 |
109 | Alkalosis (HP:0001948) | 1.91922978 |
110 | Cutaneous finger syndactyly (HP:0010554) | 1.87591182 |
111 | Dehydration (HP:0001944) | 1.87248684 |
112 | Syncope (HP:0001279) | 1.86457600 |
113 | Abnormality of potassium homeostasis (HP:0011042) | 1.85350988 |
114 | Chronic hepatic failure (HP:0100626) | 1.84326771 |
115 | Obstructive sleep apnea (HP:0002870) | 1.83753508 |
116 | Aplasia cutis congenita (HP:0001057) | 1.81273421 |
117 | Abnormality of the labia majora (HP:0012881) | 1.80909576 |
118 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.79964163 |
119 | Hypoplastic labia majora (HP:0000059) | 1.79466184 |
120 | Short hallux (HP:0010109) | 1.77890158 |
121 | Lower limb amyotrophy (HP:0007210) | 1.76034217 |
122 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.75894141 |
123 | Furrowed tongue (HP:0000221) | 1.75313708 |
124 | Spinal rigidity (HP:0003306) | 1.74369883 |
125 | Neoplasm of the adrenal cortex (HP:0100641) | 1.73923960 |
126 | Femoral bowing (HP:0002980) | 1.72639319 |
127 | Tubular atrophy (HP:0000092) | 1.72118705 |
128 | Ventricular tachycardia (HP:0004756) | 1.71367101 |
129 | Hyporeflexia of lower limbs (HP:0002600) | 1.71182891 |
130 | Hypoplastic ischia (HP:0003175) | 1.70772809 |
131 | Male pseudohermaphroditism (HP:0000037) | 1.70042561 |
132 | Sparse scalp hair (HP:0002209) | 1.69689829 |
133 | Slow-growing hair (HP:0002217) | 1.69455453 |
134 | Abnormality of hair growth rate (HP:0011363) | 1.69455453 |
135 | Testicular neoplasm (HP:0010788) | 1.69051021 |
136 | Hip contracture (HP:0003273) | 1.68933475 |
137 | Malnutrition (HP:0004395) | 1.68892661 |
138 | Hyperglycemia (HP:0003074) | 1.68592398 |
139 | Absent eyelashes (HP:0000561) | 1.68136480 |
140 | Ventricular fibrillation (HP:0001663) | 1.67666161 |
141 | Hypoplastic toenails (HP:0001800) | 1.66751484 |
142 | Nephritis (HP:0000123) | 1.66405296 |
143 | Hypokalemic alkalosis (HP:0001949) | 1.65994072 |
144 | Hypokalemia (HP:0002900) | 1.65650187 |
145 | Metabolic alkalosis (HP:0200114) | 1.65334413 |
146 | Soft skin (HP:0000977) | 1.65092452 |
147 | Lymphangioma (HP:0100764) | 1.64907028 |
148 | Upper limb muscle weakness (HP:0003484) | 1.64803852 |
149 | Turricephaly (HP:0000262) | 1.63751450 |
150 | Venous abnormality (HP:0002624) | 1.63597969 |
151 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.63395344 |
152 | Bladder diverticulum (HP:0000015) | 1.62556197 |
153 | Pili torti (HP:0003777) | 1.62520691 |
154 | Enlarged penis (HP:0000040) | 1.62182553 |
155 | Tarsal synostosis (HP:0008368) | 1.61967400 |
156 | Abnormality of the neuromuscular junction (HP:0003398) | 1.61863771 |
157 | Fatigable weakness (HP:0003473) | 1.61863771 |
158 | Limited hip movement (HP:0008800) | 1.61755901 |
159 | Hypoplasia of dental enamel (HP:0006297) | 1.61623813 |
160 | Wormian bones (HP:0002645) | 1.61574724 |
161 | Venous insufficiency (HP:0005293) | 1.61380528 |
162 | Abnormal vertebral ossification (HP:0100569) | 1.61336575 |
163 | Pancreatic fibrosis (HP:0100732) | 1.61185149 |
164 | Cystic liver disease (HP:0006706) | 1.60867765 |
165 | Short nail (HP:0001799) | 1.60422990 |
166 | Hypoplasia of the uterus (HP:0000013) | 1.59809663 |
167 | Cerebral aneurysm (HP:0004944) | 1.59177685 |
168 | Abnormality of the ischium (HP:0003174) | 1.58474904 |
169 | Radial bowing (HP:0002986) | 1.58369551 |
170 | Dysmetric saccades (HP:0000641) | 1.58228407 |
171 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.58218408 |
172 | Shawl scrotum (HP:0000049) | 1.56450416 |
173 | Hyperextensible skin (HP:0000974) | 1.55911465 |
174 | Hypohidrosis (HP:0000966) | 1.55717107 |
175 | Humeroradial synostosis (HP:0003041) | 1.55502528 |
176 | Sparse eyelashes (HP:0000653) | 1.54267260 |
177 | Bell-shaped thorax (HP:0001591) | 1.52282208 |
178 | Diaphragmatic weakness (HP:0009113) | 1.51122858 |
179 | Nephronophthisis (HP:0000090) | 1.51010274 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHB2 | 4.11730100 |
2 | MAPK15 | 3.17230388 |
3 | LATS1 | 3.09017566 |
4 | CASK | 2.97411940 |
5 | EPHA2 | 2.77520446 |
6 | LATS2 | 2.70624886 |
7 | MST1R | 2.59707967 |
8 | FER | 2.56089829 |
9 | TRIB3 | 2.48133542 |
10 | WNK4 | 2.26219074 |
11 | DDR2 | 2.16024370 |
12 | EPHA3 | 2.11360139 |
13 | LMTK2 | 2.09066103 |
14 | PDGFRA | 2.01745310 |
15 | OXSR1 | 1.99062723 |
16 | MST4 | 1.96925290 |
17 | MAP3K2 | 1.95408899 |
18 | ERBB4 | 1.85343279 |
19 | RIPK1 | 1.67410515 |
20 | MET | 1.65744177 |
21 | NEK6 | 1.65224142 |
22 | MAP3K6 | 1.61696468 |
23 | PTK2 | 1.54333450 |
24 | PAK3 | 1.54239016 |
25 | NTRK2 | 1.53052640 |
26 | SIK1 | 1.42958027 |
27 | MAP3K3 | 1.40591805 |
28 | WNK3 | 1.40553382 |
29 | PKN2 | 1.38611392 |
30 | FRK | 1.37606478 |
31 | BMX | 1.32416961 |
32 | SGK494 | 1.32393871 |
33 | SGK223 | 1.32393871 |
34 | MAP3K9 | 1.28030372 |
35 | PIK3CA | 1.25581532 |
36 | PRKG2 | 1.25308495 |
37 | FGFR4 | 1.23019605 |
38 | MAP2K1 | 1.20048920 |
39 | MARK1 | 1.19378618 |
40 | INSRR | 1.17746788 |
41 | PTK6 | 1.17343902 |
42 | STK38L | 1.17001159 |
43 | SGK2 | 1.16293072 |
44 | DYRK1B | 1.09094370 |
45 | ROCK1 | 1.05881872 |
46 | STK38 | 1.04180186 |
47 | MAP2K2 | 1.03113066 |
48 | ACVR1B | 1.01441557 |
49 | TTN | 1.00366783 |
50 | TAOK1 | 1.00087636 |
51 | MYLK | 0.96119984 |
52 | MAPKAPK3 | 0.94836584 |
53 | EPHA4 | 0.94417870 |
54 | PRPF4B | 0.92362790 |
55 | PAK4 | 0.92064363 |
56 | CDC42BPA | 0.91539713 |
57 | NTRK1 | 0.89732608 |
58 | CAMK1G | 0.89411712 |
59 | ERBB2 | 0.89207513 |
60 | MKNK2 | 0.88901414 |
61 | RET | 0.88883942 |
62 | HIPK2 | 0.86938540 |
63 | AKT3 | 0.86222548 |
64 | EPHB1 | 0.85062195 |
65 | PNCK | 0.84811108 |
66 | NTRK3 | 0.84614106 |
67 | PAK2 | 0.83060786 |
68 | PRKAA2 | 0.81982978 |
69 | PRKCI | 0.79569031 |
70 | PRKD3 | 0.78948822 |
71 | FGFR1 | 0.77901124 |
72 | MAP3K7 | 0.77027539 |
73 | MTOR | 0.76088091 |
74 | SGK3 | 0.75872789 |
75 | PIK3CG | 0.75814216 |
76 | ERBB3 | 0.75424322 |
77 | MAP3K4 | 0.74991589 |
78 | SMG1 | 0.73900071 |
79 | CAMK1D | 0.73369504 |
80 | NME1 | 0.71804815 |
81 | ERN1 | 0.70201004 |
82 | MAP2K4 | 0.68434537 |
83 | DYRK1A | 0.67746023 |
84 | MAPKAPK5 | 0.65853886 |
85 | PDGFRB | 0.65120842 |
86 | TGFBR1 | 0.64862799 |
87 | CAMKK1 | 0.64148332 |
88 | CAMK2B | 0.63530112 |
89 | LIMK1 | 0.63457435 |
90 | CDK12 | 0.63186221 |
91 | SGK1 | 0.63115495 |
92 | GSK3A | 0.62245212 |
93 | STK24 | 0.60876304 |
94 | PHKG2 | 0.60522366 |
95 | PHKG1 | 0.60522366 |
96 | TYRO3 | 0.59393963 |
97 | PDPK1 | 0.58603257 |
98 | PRKCE | 0.58514750 |
99 | RPS6KB2 | 0.58019577 |
100 | CDK19 | 0.57946959 |
101 | MARK2 | 0.57540493 |
102 | RPS6KA2 | 0.56830836 |
103 | FGFR2 | 0.56402332 |
104 | PRKAA1 | 0.55505446 |
105 | PRKCZ | 0.55345732 |
106 | UHMK1 | 0.55144942 |
107 | TRPM7 | 0.55021407 |
108 | MAPK13 | 0.54106607 |
109 | MAP2K6 | 0.52743350 |
110 | CDK5 | 0.51282899 |
111 | MAPK12 | 0.51243562 |
112 | ALK | 0.51123900 |
113 | ROCK2 | 0.50024159 |
114 | MAP2K7 | 0.49877449 |
115 | GRK1 | 0.49183868 |
116 | PAK6 | 0.47960394 |
117 | MINK1 | 0.47332737 |
118 | ADRBK1 | 0.47033220 |
119 | DMPK | 0.46578834 |
120 | TIE1 | 0.46312327 |
121 | ICK | 0.44809481 |
122 | DYRK2 | 0.44658659 |
123 | ILK | 0.43289822 |
124 | STK3 | 0.41758676 |
125 | LRRK2 | 0.41235736 |
126 | BRD4 | 0.40489370 |
127 | DAPK2 | 0.40468272 |
128 | CAMK2G | 0.39967121 |
129 | SIK2 | 0.39931056 |
130 | MAP3K1 | 0.38905698 |
131 | ABL2 | 0.38573758 |
132 | EEF2K | 0.38426175 |
133 | WNK1 | 0.38411783 |
134 | BCR | 0.38191727 |
135 | RPS6KB1 | 0.37659737 |
136 | PRKD1 | 0.37021279 |
137 | CAMK2D | 0.36064300 |
138 | STK11 | 0.35319397 |
139 | MAPK9 | 0.33954713 |
140 | MATK | 0.33394471 |
141 | PDK2 | 0.32549634 |
142 | STK16 | 0.32536647 |
143 | FGFR3 | 0.32411570 |
144 | MAPK7 | 0.31575623 |
145 | IGF1R | 0.31349424 |
146 | SRC | 0.30906405 |
147 | STK39 | 0.30665718 |
148 | CSNK1E | 0.30634001 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 3.49303945 |
2 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.69164663 |
3 | Focal adhesion_Homo sapiens_hsa04510 | 2.10097313 |
4 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.98168358 |
5 | Axon guidance_Homo sapiens_hsa04360 | 1.94461279 |
6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.89351258 |
7 | Amoebiasis_Homo sapiens_hsa05146 | 1.88854787 |
8 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.87180074 |
9 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.87159151 |
10 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.85636790 |
11 | Bladder cancer_Homo sapiens_hsa05219 | 1.82092362 |
12 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.82033263 |
13 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.78855136 |
14 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.73801179 |
15 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.73637154 |
16 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.70114387 |
17 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.69725570 |
18 | Retinol metabolism_Homo sapiens_hsa00830 | 1.69428054 |
19 | Adherens junction_Homo sapiens_hsa04520 | 1.67185369 |
20 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.64724193 |
21 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.64068653 |
22 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.62403330 |
23 | Tight junction_Homo sapiens_hsa04530 | 1.61533715 |
24 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.60833282 |
25 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.51657357 |
26 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.49611765 |
27 | Insulin secretion_Homo sapiens_hsa04911 | 1.49440512 |
28 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.48955225 |
29 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.45623647 |
30 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.43643781 |
31 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.43021983 |
32 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.38699693 |
33 | Cocaine addiction_Homo sapiens_hsa05030 | 1.36447210 |
34 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.34884500 |
35 | Melanogenesis_Homo sapiens_hsa04916 | 1.34045978 |
36 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.33956910 |
37 | Nicotine addiction_Homo sapiens_hsa05033 | 1.31747503 |
38 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.26395594 |
39 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.25934009 |
40 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.20515039 |
41 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.19001480 |
42 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.18028227 |
43 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.17700396 |
44 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.17232501 |
45 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.17068860 |
46 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.15963209 |
47 | Renin secretion_Homo sapiens_hsa04924 | 1.13837172 |
48 | Histidine metabolism_Homo sapiens_hsa00340 | 1.13159724 |
49 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.10461536 |
50 | Gap junction_Homo sapiens_hsa04540 | 1.09815948 |
51 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.08954155 |
52 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.08758590 |
53 | Endometrial cancer_Homo sapiens_hsa05213 | 1.03877995 |
54 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.02383917 |
55 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.00563677 |
56 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.00399238 |
57 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.98883446 |
58 | Prion diseases_Homo sapiens_hsa05020 | 0.98646804 |
59 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.98237521 |
60 | Thyroid cancer_Homo sapiens_hsa05216 | 0.96316651 |
61 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.94982794 |
62 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.94450710 |
63 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.94092282 |
64 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.94000997 |
65 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.91815783 |
66 | Mineral absorption_Homo sapiens_hsa04978 | 0.90685939 |
67 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.90070375 |
68 | Phototransduction_Homo sapiens_hsa04744 | 0.89953944 |
69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.89266242 |
70 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.88797452 |
71 | Circadian rhythm_Homo sapiens_hsa04710 | 0.88550998 |
72 | Melanoma_Homo sapiens_hsa05218 | 0.87930886 |
73 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.87827347 |
74 | Lysine degradation_Homo sapiens_hsa00310 | 0.86975092 |
75 | ABC transporters_Homo sapiens_hsa02010 | 0.86449985 |
76 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.86218113 |
77 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.85436074 |
78 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.85409241 |
79 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.83286052 |
80 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.83103753 |
81 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.82722914 |
82 | Pathways in cancer_Homo sapiens_hsa05200 | 0.81086723 |
83 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.80556330 |
84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.80302009 |
85 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.79816778 |
86 | Glioma_Homo sapiens_hsa05214 | 0.79710928 |
87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.78771437 |
88 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.78600916 |
89 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.78369781 |
90 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.78291748 |
91 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.77897662 |
92 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.77380755 |
93 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.77074321 |
94 | Prostate cancer_Homo sapiens_hsa05215 | 0.76983732 |
95 | Salivary secretion_Homo sapiens_hsa04970 | 0.76834919 |
96 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.73587812 |
97 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.73346048 |
98 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.71855575 |
99 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.69204974 |
100 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.67783839 |
101 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.67510147 |
102 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.66992540 |
103 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.66090412 |
104 | GABAergic synapse_Homo sapiens_hsa04727 | 0.65816758 |
105 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.63672715 |
106 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.63444265 |
107 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.62843809 |
108 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.62619283 |
109 | Long-term depression_Homo sapiens_hsa04730 | 0.62198734 |
110 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.61433208 |
111 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.61116444 |
112 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.60740809 |
113 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.60592632 |
114 | Circadian entrainment_Homo sapiens_hsa04713 | 0.60274895 |
115 | Morphine addiction_Homo sapiens_hsa05032 | 0.59263765 |
116 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.58401314 |
117 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.57894993 |
118 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.57892631 |
119 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.57863092 |
120 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.57713488 |
121 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.57546929 |
122 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.57227777 |
123 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.56028308 |
124 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.55747689 |
125 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.55201106 |
126 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.54187706 |
127 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.53918179 |
128 | Bile secretion_Homo sapiens_hsa04976 | 0.52805283 |
129 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.52496792 |
130 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.52368376 |
131 | Insulin resistance_Homo sapiens_hsa04931 | 0.51383984 |
132 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.50063339 |
133 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.49796561 |
134 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.49325761 |
135 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.49193589 |
136 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.48880397 |
137 | Taste transduction_Homo sapiens_hsa04742 | 0.44696825 |
138 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.44457649 |
139 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.44243935 |
140 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43807951 |
141 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.43675994 |
142 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.43375648 |
143 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.42940666 |
144 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41457737 |
145 | Olfactory transduction_Homo sapiens_hsa04740 | 0.39429049 |