ZC3H11A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1histone H3-K36 demethylation (GO:0070544)4.28225176
2phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)4.09930620
3regulation of RNA export from nucleus (GO:0046831)3.98950690
4regulation of nucleobase-containing compound transport (GO:0032239)3.73084173
5interkinetic nuclear migration (GO:0022027)3.70630681
6monoubiquitinated protein deubiquitination (GO:0035520)3.51652607
7histone H3-K4 trimethylation (GO:0080182)3.46871266
8negative regulation of DNA repair (GO:0045738)3.45299795
9COPII vesicle coating (GO:0048208)3.38642698
10histone lysine demethylation (GO:0070076)3.38039125
11mesenchymal cell differentiation involved in renal system development (GO:2001012)3.37683024
12mesenchymal cell differentiation involved in kidney development (GO:0072161)3.37683024
13negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.23710270
14negative regulation of translation, ncRNA-mediated (GO:0040033)3.23710270
15regulation of translation, ncRNA-mediated (GO:0045974)3.23710270
16mesenchymal cell differentiation (GO:0048762)3.19772660
17embryonic process involved in female pregnancy (GO:0060136)3.18191353
18outer ear morphogenesis (GO:0042473)3.16987485
19lymph vessel development (GO:0001945)3.14168125
20definitive hemopoiesis (GO:0060216)3.12912464
21negative regulation of keratinocyte proliferation (GO:0010839)3.10212335
22desmosome organization (GO:0002934)3.07095542
23radial glial cell differentiation (GO:0060019)3.04094548
24regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.00200093
25neural crest cell development (GO:0014032)2.94172191
26hemidesmosome assembly (GO:0031581)2.91908140
27histone H3-K9 demethylation (GO:0033169)2.91094729
28positive regulation of hormone biosynthetic process (GO:0046886)2.91082516
29sister chromatid cohesion (GO:0007062)2.83152616
30regulation of Rac protein signal transduction (GO:0035020)2.82839721
31mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)2.82830042
32* poly(A)+ mRNA export from nucleus (GO:0016973)2.82144857
33peptidyl-threonine modification (GO:0018210)2.81523722
34peptidyl-threonine phosphorylation (GO:0018107)2.80550804
35nuclear pore complex assembly (GO:0051292)2.73375174
36Golgi to endosome transport (GO:0006895)2.73352479
37hypotonic response (GO:0006971)2.72585682
38negative regulation of erythrocyte differentiation (GO:0045647)2.71168886
39nucleus localization (GO:0051647)2.70074341
40dosage compensation (GO:0007549)2.69547862
41pre-miRNA processing (GO:0031054)2.68520703
42cellular response to ethanol (GO:0071361)2.67003558
43regulation of cardioblast proliferation (GO:0003264)2.66091050
44regulation of secondary heart field cardioblast proliferation (GO:0003266)2.66091050
45protein dealkylation (GO:0008214)2.65975794
46protein demethylation (GO:0006482)2.65975794
47mesodermal cell differentiation (GO:0048333)2.64111143
48positive regulation of protein import into nucleus, translocation (GO:0033160)2.61324305
49positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.60979673
50replicative senescence (GO:0090399)2.59810516
51lung vasculature development (GO:0060426)2.59226805
52mitotic sister chromatid cohesion (GO:0007064)2.57545125
53megakaryocyte development (GO:0035855)2.57289021
54histone H4-K16 acetylation (GO:0043984)2.56293708
55gland morphogenesis (GO:0022612)2.55892307
56mesenchymal cell development (GO:0014031)2.55767689
57mesenchyme morphogenesis (GO:0072132)2.54251146
58notochord development (GO:0030903)2.53194904
59chondrocyte proliferation (GO:0035988)2.52720369
60response to epidermal growth factor (GO:0070849)2.52678519
61positive regulation of gamma-delta T cell activation (GO:0046645)2.52067428
62protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)2.50402381
63DNA synthesis involved in DNA repair (GO:0000731)2.49941771
64positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.48099610
65coronary vasculature morphogenesis (GO:0060977)2.47991905
66positive regulation of interleukin-8 secretion (GO:2000484)2.47330074
67embryonic camera-type eye morphogenesis (GO:0048596)2.45855076
68regulation of heart morphogenesis (GO:2000826)2.45644152
69hepatocyte apoptotic process (GO:0097284)2.45503039
70negative regulation of fatty acid transport (GO:2000192)2.44817737
71regulation of NFAT protein import into nucleus (GO:0051532)2.43010229
72nuclear pore organization (GO:0006999)2.42523574
73regulation of transforming growth factor beta2 production (GO:0032909)2.42507526
74embryonic skeletal joint morphogenesis (GO:0060272)2.42036554
75proximal/distal pattern formation (GO:0009954)2.40901212
76negative regulation of histone methylation (GO:0031061)2.39746311
77establishment of nucleus localization (GO:0040023)2.39476866
78regulation of gamma-delta T cell differentiation (GO:0045586)2.39083929
79positive regulation of granulocyte differentiation (GO:0030854)2.38926172
80insulin-like growth factor receptor signaling pathway (GO:0048009)2.37981367
81polarized epithelial cell differentiation (GO:0030859)2.37271315
82histone lysine methylation (GO:0034968)2.36933515
83glomerulus development (GO:0032835)2.36800700
84paraxial mesoderm development (GO:0048339)2.36384888
85cell differentiation involved in metanephros development (GO:0072202)2.36192098
86pore complex assembly (GO:0046931)2.35640900
87regulation of cell proliferation involved in heart morphogenesis (GO:2000136)2.35459805
88glomerular visceral epithelial cell development (GO:0072015)2.35176499
89telomere maintenance via telomerase (GO:0007004)2.34877255
90lateral sprouting from an epithelium (GO:0060601)2.33705249
91regulation of histone H3-K27 methylation (GO:0061085)2.33428473
92stem cell development (GO:0048864)2.33257192
93positive regulation of DNA-templated transcription, initiation (GO:2000144)2.33206738
94regulation of protein polyubiquitination (GO:1902914)2.32514790
95iron ion import (GO:0097286)2.32429855
96regulation of establishment of cell polarity (GO:2000114)2.30868009
97DNA topological change (GO:0006265)2.30816176
98lymphangiogenesis (GO:0001946)2.30277909
99regulation of cell fate specification (GO:0042659)2.30056704
100histone H3-K4 methylation (GO:0051568)2.29996708
101vesicle coating (GO:0006901)2.28714563
102regulation of histone methylation (GO:0031060)2.28560230
103morphogenesis of an epithelial sheet (GO:0002011)2.27679591
104smooth muscle tissue development (GO:0048745)2.27078779
105epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.27013199
106phosphatidylinositol dephosphorylation (GO:0046856)2.26893975
107metanephros development (GO:0001656)2.26427490
108peptidyl-lysine trimethylation (GO:0018023)2.26022248
109regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.25258913
110metanephric mesenchyme development (GO:0072075)2.23741957
111nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.23625144
112mitotic chromosome condensation (GO:0007076)2.22939754
113activation of Rac GTPase activity (GO:0032863)2.22919616
114negative regulation of neurotransmitter secretion (GO:0046929)2.22910290
115cell proliferation involved in kidney development (GO:0072111)2.21791780
116genitalia morphogenesis (GO:0035112)2.21738867
117embryonic retina morphogenesis in camera-type eye (GO:0060059)2.21717812
118regulation of keratinocyte proliferation (GO:0010837)2.21665856
119nucleus organization (GO:0006997)2.21212968
120protein export from nucleus (GO:0006611)2.20169442
121early endosome to late endosome transport (GO:0045022)2.20087317
122mammary gland development (GO:0030879)2.19954895
123regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.19408679
124negative regulation of stem cell proliferation (GO:2000647)2.19312593
125positive regulation of cartilage development (GO:0061036)2.19085048
126somite development (GO:0061053)2.18982012
127wound healing, spreading of epidermal cells (GO:0035313)2.17933519
128regulation of interleukin-8 secretion (GO:2000482)2.16485118
129mRNA stabilization (GO:0048255)2.15779072
130RNA stabilization (GO:0043489)2.15779072
131growth hormone receptor signaling pathway (GO:0060396)2.15266873
132interleukin-6-mediated signaling pathway (GO:0070102)2.15096983
133cytoplasmic mRNA processing body assembly (GO:0033962)2.14935082
134embryonic eye morphogenesis (GO:0048048)2.14769635
135positive regulation of catenin import into nucleus (GO:0035413)2.14665989
136pituitary gland development (GO:0021983)2.13841547
137glucocorticoid receptor signaling pathway (GO:0042921)2.12869103
138positive regulation of macroautophagy (GO:0016239)2.12806638
139regulation of gamma-delta T cell activation (GO:0046643)2.11817070
140lipid translocation (GO:0034204)2.11805471
141phospholipid translocation (GO:0045332)2.11805471
142regulation of histone H3-K4 methylation (GO:0051569)2.11787234
143organ formation (GO:0048645)2.11666550
144phospholipid dephosphorylation (GO:0046839)2.11576028
145negative regulation of anoikis (GO:2000811)2.11514860
146face morphogenesis (GO:0060325)2.11339346
147regulation of cell proliferation involved in kidney development (GO:1901722)2.11007379
148mRNA modification (GO:0016556)2.10511389
149embryonic cranial skeleton morphogenesis (GO:0048701)2.10477238
150B cell receptor signaling pathway (GO:0050853)2.10426456
151histone demethylation (GO:0016577)2.10424385
152regulation of sister chromatid cohesion (GO:0007063)2.10318325
153positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.09922277
154cochlea morphogenesis (GO:0090103)2.09823399
155establishment of epithelial cell polarity (GO:0090162)2.09197706
156negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)2.09079398
157face development (GO:0060324)2.08550211
158cell-cell signaling involved in cell fate commitment (GO:0045168)2.08516055
159mesenchymal to epithelial transition (GO:0060231)2.08406807
160corticosteroid receptor signaling pathway (GO:0031958)2.08352687
161regulation of posttranscriptional gene silencing (GO:0060147)2.07780601
162regulation of gene silencing by miRNA (GO:0060964)2.07780601
163regulation of gene silencing by RNA (GO:0060966)2.07780601
164negative regulation of chondrocyte differentiation (GO:0032331)2.07613746
165phosphatidylinositol phosphorylation (GO:0046854)2.07486005
166chondrocyte development (GO:0002063)2.07370128
167regulation of establishment or maintenance of cell polarity (GO:0032878)2.06906481
168branching involved in ureteric bud morphogenesis (GO:0001658)2.06766360
169Golgi organization (GO:0007030)2.06727809
170positive regulation of SMAD protein import into nucleus (GO:0060391)2.06704880
171regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.06501111
172DNA duplex unwinding (GO:0032508)2.06151570
173peptidyl-lysine methylation (GO:0018022)2.06099777
174regulation of pigment cell differentiation (GO:0050932)2.05817049
175positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261)2.05424765
176platelet-derived growth factor receptor signaling pathway (GO:0048008)2.05235614
177collagen fibril organization (GO:0030199)2.04914658
178keratinocyte proliferation (GO:0043616)2.04769863

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.38161171
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.10930388
3TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.61514187
4E2F7_22180533_ChIP-Seq_HELA_Human3.40463748
5RBPJ_22232070_ChIP-Seq_NCS_Mouse3.29515112
6GATA1_22025678_ChIP-Seq_K562_Human3.16106043
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.95541610
8TRIM28_21343339_ChIP-Seq_HEK293_Human2.94663541
9EGR1_19374776_ChIP-ChIP_THP-1_Human2.85716034
10SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.74476899
11TP63_19390658_ChIP-ChIP_HaCaT_Human2.60347309
12CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.44794508
13STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.35245044
14WT1_19549856_ChIP-ChIP_CCG9911_Human2.28321872
15* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.21421660
16ESR1_21235772_ChIP-Seq_MCF-7_Human2.17156957
17ESR1_20079471_ChIP-ChIP_T-47D_Human2.17019400
18SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.06410427
19SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.06410427
20NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.00605540
21KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.99182009
22KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.99182009
23KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.99182009
24ZNF217_24962896_ChIP-Seq_MCF-7_Human1.91134878
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.87893493
26CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.85807976
27FOXM1_23109430_ChIP-Seq_U2OS_Human1.83943004
28SMAD_19615063_ChIP-ChIP_OVARY_Human1.79923282
29CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.76669338
30ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.73227582
31FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.72644994
32SALL4_18804426_ChIP-ChIP_XEN_Mouse1.69934550
33SOX9_24532713_ChIP-Seq_HFSC_Mouse1.65293735
34STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.63744584
35CJUN_26792858_Chip-Seq_BT549_Human1.62723517
36MYB_21317192_ChIP-Seq_ERMYB_Mouse1.61442147
37EWS_26573619_Chip-Seq_HEK293_Human1.60284016
38BRD4_25478319_ChIP-Seq_HGPS_Human1.60157697
39Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.57192338
40BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.56840378
41FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.52225288
42CTNNB1_20460455_ChIP-Seq_HCT116_Human1.50831485
43GATA2_21666600_ChIP-Seq_HMVEC_Human1.47336208
44* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.46691616
45TP53_18474530_ChIP-ChIP_U2OS_Human1.44933593
46SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.44444977
47TCF4_18268006_ChIP-ChIP_LS174T_Human1.36222276
48TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.35084985
49FUS_26573619_Chip-Seq_HEK293_Human1.33473752
50HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.31471721
51TCF7_22412390_ChIP-Seq_EML_Mouse1.30997510
52RUNX_20019798_ChIP-Seq_JUKART_Human1.29008681
53SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.28495082
54AHR_22903824_ChIP-Seq_MCF-7_Human1.27574905
55ISL1_27105846_Chip-Seq_CPCs_Mouse1.27166271
56PIAS1_25552417_ChIP-Seq_VCAP_Human1.26931104
57EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.26318891
58CLOCK_20551151_ChIP-Seq_293T_Human1.24944415
59* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.24922733
60NOTCH1_21737748_ChIP-Seq_TLL_Human1.21989160
61POU5F1_16153702_ChIP-ChIP_HESCs_Human1.21673177
62ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.20511078
63HIF1A_21447827_ChIP-Seq_MCF-7_Human1.20327999
64VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.20134966
65SOX2_20726797_ChIP-Seq_SW620_Human1.19960508
66* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.19209496
67PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.15801938
68MYC_22102868_ChIP-Seq_BL_Human1.15620147
69* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.15597711
70* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.14963653
71* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.14963653
72STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.14235944
73CDX2_20551321_ChIP-Seq_CACO-2_Human1.13595213
74FLI1_27457419_Chip-Seq_LIVER_Mouse1.12538200
75* EP300_21415370_ChIP-Seq_HL-1_Mouse1.12047463
76FOXM1_26456572_ChIP-Seq_MCF-7_Human1.11997472
77FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.11761115
78RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.11226968
79EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.11195365
80WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.10900735
81KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.10275814
82SOX2_27498859_Chip-Seq_STOMACH_Mouse1.10108946
83UBF1/2_26484160_Chip-Seq_HMECs_Human1.09896421
84TP53_16413492_ChIP-PET_HCT116_Human1.09743607
85CDX2_19796622_ChIP-Seq_MESCs_Mouse1.09242766
86ARNT_22903824_ChIP-Seq_MCF-7_Human1.09097184
87FOXA2_19822575_ChIP-Seq_HepG2_Human1.08436597
88FOXO3_23340844_ChIP-Seq_DLD1_Human1.08253411
89FOXA1_26743006_Chip-Seq_LNCaP-abl_Human1.07635506
90ELK1_19687146_ChIP-ChIP_HELA_Human1.06973172
91FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.06950958
92TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.06477189
93* CHD1_26751641_Chip-Seq_LNCaP_Human1.06378155
94STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.05923231
95PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.05034331
96PPAR_26484153_Chip-Seq_NCI-H1993_Human1.04978040
97AR_21909140_ChIP-Seq_LNCAP_Human1.04879504
98* MYB_26560356_Chip-Seq_TH1_Human1.04850215
99PKCTHETA_26484144_Chip-Seq_BREAST_Human1.04569299
100* NANOG_18555785_Chip-Seq_ESCs_Mouse1.04273283
101RXR_22108803_ChIP-Seq_LS180_Human1.02687164
102PCGF2_27294783_Chip-Seq_ESCs_Mouse1.01969644
103PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00676093
104* E2F1_18555785_Chip-Seq_ESCs_Mouse1.00661238
105PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.00577924
106YAP1_20516196_ChIP-Seq_MESCs_Mouse1.00512848
107SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.00093376
108GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.99655258
109PU_27001747_Chip-Seq_BMDM_Mouse0.98894927
110VDR_24787735_ChIP-Seq_THP-1_Human0.98648069
111MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.98325643
112MYB_26560356_Chip-Seq_TH2_Human0.97786189
113ER_23166858_ChIP-Seq_MCF-7_Human0.97073239
114AR_21572438_ChIP-Seq_LNCaP_Human0.96917153
115TP63_23658742_ChIP-Seq_EP156T_Human0.96429126
116SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.96287484
117* CMYC_18555785_Chip-Seq_ESCs_Mouse0.95373429
118P300_27058665_Chip-Seq_ZR-75-30cells_Human0.95142915
119KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.94809651
120* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.94765470
121* NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.94532738
122IRF8_22096565_ChIP-ChIP_GC-B_Human0.94053934
123RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.93154543
124RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.92432477
125DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.92426484
126POU3F2_20337985_ChIP-ChIP_501MEL_Human0.92360053
127AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.91761689
128ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.90567568
129CDX2_22108803_ChIP-Seq_LS180_Human0.90231304
130KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.89378095
131NFIB_24661679_ChIP-Seq_LUNG_Mouse0.88305368
132E2F1_21310950_ChIP-Seq_MCF-7_Human0.87231370
133TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.87156345
134* TCF3_18692474_ChIP-Seq_MESCs_Mouse0.86644277
135SUZ12_27294783_Chip-Seq_NPCs_Mouse0.86508747
136* TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85891463
137CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.85690516
138GATA4_25053715_ChIP-Seq_YYC3_Human0.85374067
139NFE2_27457419_Chip-Seq_LIVER_Mouse0.85275267
140IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.84537856

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003941_abnormal_skin_development3.41114982
2MP0000569_abnormal_digit_pigmentation3.03321547
3MP0002396_abnormal_hematopoietic_system2.99205602
4MP0010234_abnormal_vibrissa_follicle2.88604170
5MP0002877_abnormal_melanocyte_morpholog2.68070089
6MP0003300_gastrointestinal_ulcer2.47188192
7MP0001879_abnormal_lymphatic_vessel2.43823033
8MP0002166_altered_tumor_susceptibility2.42796155
9MP0010368_abnormal_lymphatic_system2.28174868
10MP0004272_abnormal_basement_membrane2.20892585
11MP0002254_reproductive_system_inflammat2.12025579
12MP0005409_darkened_coat_color2.09554381
13MP0010352_gastrointestinal_tract_polyps2.03275222
14MP0002009_preneoplasia2.01937452
15MP0000566_synostosis1.98828896
16MP0008057_abnormal_DNA_replication1.98517865
17MP0003763_abnormal_thymus_physiology1.96866779
18MP0003787_abnormal_imprinting1.94753615
19MP0010030_abnormal_orbit_morphology1.93405770
20MP0009053_abnormal_anal_canal1.93179750
21MP0000516_abnormal_urinary_system1.89425054
22MP0005367_renal/urinary_system_phenotyp1.89425054
23MP0003385_abnormal_body_wall1.87756445
24MP0003566_abnormal_cell_adhesion1.87581378
25MP0006054_spinal_hemorrhage1.84731018
26MP0002060_abnormal_skin_morphology1.84393412
27MP0005503_abnormal_tendon_morphology1.80359530
28MP0002006_tumorigenesis1.68825656
29MP0010307_abnormal_tumor_latency1.67598964
30MP0008438_abnormal_cutaneous_collagen1.67390975
31MP0009250_abnormal_appendicular_skeleto1.65961003
32MP0004185_abnormal_adipocyte_glucose1.64386212
33MP0003091_abnormal_cell_migration1.63475505
34MP0005275_abnormal_skin_tensile1.62554614
35MP0000762_abnormal_tongue_morphology1.62535032
36MP0002098_abnormal_vibrissa_morphology1.55539410
37MP0008007_abnormal_cellular_replicative1.55147511
38MP0003656_abnormal_erythrocyte_physiolo1.54759165
39MP0009384_cardiac_valve_regurgitation1.50551922
40MP0003942_abnormal_urinary_system1.47530860
41MP0002938_white_spotting1.47315266
42MP0003755_abnormal_palate_morphology1.45552588
43MP0000383_abnormal_hair_follicle1.42440694
44MP0002796_impaired_skin_barrier1.42005896
45MP0003935_abnormal_craniofacial_develop1.38058321
46MP0003123_paternal_imprinting1.36800142
47MP0000767_abnormal_smooth_muscle1.34295577
48MP0000427_abnormal_hair_cycle1.32268984
49MP0003279_aneurysm1.31320627
50MP0000432_abnormal_head_morphology1.27805902
51MP0005508_abnormal_skeleton_morphology1.27618487
52MP0003828_pulmonary_edema1.27518321
53MP0003937_abnormal_limbs/digits/tail_de1.26690111
54MP0005171_absent_coat_pigmentation1.26356131
55MP0000467_abnormal_esophagus_morphology1.26050830
56MP0004381_abnormal_hair_follicle1.25695226
57MP0003121_genomic_imprinting1.23629221
58MP0003943_abnormal_hepatobiliary_system1.21386198
59MP0001915_intracranial_hemorrhage1.21216329
60MP0000678_abnormal_parathyroid_gland1.19070283
61MP0002177_abnormal_outer_ear1.12949257
62MP0003705_abnormal_hypodermis_morpholog1.11944253
63MP0002925_abnormal_cardiovascular_devel1.11842380
64MP0003453_abnormal_keratinocyte_physiol1.09213538
65MP0002233_abnormal_nose_morphology1.08146794
66MP0000049_abnormal_middle_ear1.07970957
67MP0002108_abnormal_muscle_morphology1.06364333
68MP0001216_abnormal_epidermal_layer1.05942676
69MP0010678_abnormal_skin_adnexa1.05883961
70MP0000703_abnormal_thymus_morphology1.05621745
71MP0000579_abnormal_nail_morphology1.05233313
72MP0002249_abnormal_larynx_morphology1.04387311
73MP0000537_abnormal_urethra_morphology1.04312177
74MP0000613_abnormal_salivary_gland1.04113309
75MP0009780_abnormal_chondrocyte_physiolo1.04013897
76MP0003045_fibrosis1.03960678
77MP0002109_abnormal_limb_morphology1.02294396
78MP0002932_abnormal_joint_morphology1.02018884
79MP0003950_abnormal_plasma_membrane1.01927298
80MP0001661_extended_life_span1.01516078
81MP0001270_distended_abdomen0.99880682
82MP0005023_abnormal_wound_healing0.98533893
83MP0000428_abnormal_craniofacial_morphol0.98405445
84MP0001851_eye_inflammation0.98133874
85MP0004808_abnormal_hematopoietic_stem0.96313627
86MP0003221_abnormal_cardiomyocyte_apopto0.96146640
87MP0001730_embryonic_growth_arrest0.95941133
88MP0001286_abnormal_eye_development0.94818167
89MP0004197_abnormal_fetal_growth/weight/0.93925487
90MP0003936_abnormal_reproductive_system0.93038201
91MP0003693_abnormal_embryo_hatching0.92027443
92MP0005408_hypopigmentation0.91781927
93MP0002115_abnormal_skeleton_extremities0.91342343
94MP0003567_abnormal_fetal_cardiomyocyte0.90393107
95MP0000647_abnormal_sebaceous_gland0.90379847
96MP0000371_diluted_coat_color0.89631786
97MP0000015_abnormal_ear_pigmentation0.89454411
98MP0005248_abnormal_Harderian_gland0.89282011
99MP0003890_abnormal_embryonic-extraembry0.89273294
100MP0010094_abnormal_chromosome_stability0.89204226
101MP0004947_skin_inflammation0.88812482
102MP0005621_abnormal_cell_physiology0.88732474
103MP0000350_abnormal_cell_proliferation0.88654062
104MP0002971_abnormal_brown_adipose0.88653582
105MP0005501_abnormal_skin_physiology0.87987818
106MP0010630_abnormal_cardiac_muscle0.87960814
107MP0005666_abnormal_adipose_tissue0.87790198
108MP0004264_abnormal_extraembryonic_tissu0.87629190
109MP0000465_gastrointestinal_hemorrhage0.87450571
110MP0001784_abnormal_fluid_regulation0.87016279
111MP0002111_abnormal_tail_morphology0.86682886
112MP0002086_abnormal_extraembryonic_tissu0.86598686
113MP0005076_abnormal_cell_differentiation0.86227551
114MP0000013_abnormal_adipose_tissue0.85475976
115MP0000462_abnormal_digestive_system0.85252676
116MP0001697_abnormal_embryo_size0.85093153
117MP0003119_abnormal_digestive_system0.85044388
118MP0002088_abnormal_embryonic_growth/wei0.84464516
119MP0001346_abnormal_lacrimal_gland0.84376456
120MP0000627_abnormal_mammary_gland0.84169821
121MP0003984_embryonic_growth_retardation0.83932971
122MP0004084_abnormal_cardiac_muscle0.83873838
123MP0001293_anophthalmia0.83668994
124MP0002896_abnormal_bone_mineralization0.83377729
125MP0001177_atelectasis0.83147380
126MP0003115_abnormal_respiratory_system0.82977556
127MP0009115_abnormal_fat_cell0.81436303
128MP0000377_abnormal_hair_follicle0.81382897
129MP0009703_decreased_birth_body0.80950494
130MP0000163_abnormal_cartilage_morphology0.80669543
131MP0000003_abnormal_adipose_tissue0.80515574
132MP0002116_abnormal_craniofacial_bone0.79425761
133MP0004134_abnormal_chest_morphology0.79050941
134MP0000534_abnormal_ureter_morphology0.78967339
135MP0005220_abnormal_exocrine_pancreas0.78565978
136MP0002128_abnormal_blood_circulation0.78170960
137MP0005380_embryogenesis_phenotype0.77941851
138MP0001672_abnormal_embryogenesis/_devel0.77941851
139MP0005375_adipose_tissue_phenotype0.77729750
140MP0002928_abnormal_bile_duct0.77587795
141MP0003868_abnormal_feces_composition0.76988708
142MP0002084_abnormal_developmental_patter0.76822613
143MP0000733_abnormal_muscle_development0.76659575
144MP0001835_abnormal_antigen_presentation0.76403951
145MP0001243_abnormal_dermal_layer0.71262128
146MP0005451_abnormal_body_composition0.69665225
147MP0008004_abnormal_stomach_pH0.68514949
148MP0000266_abnormal_heart_morphology0.68256766
149MP0009931_abnormal_skin_appearance0.66775682
150MP0002398_abnormal_bone_marrow0.66707129
151MP0004036_abnormal_muscle_relaxation0.66394312
152MP0001191_abnormal_skin_condition0.65610928
153MP0005187_abnormal_penis_morphology0.65424100

Predicted human phenotypes

RankGene SetZ-score
1Papillary thyroid carcinoma (HP:0002895)4.05120661
2Lip pit (HP:0100267)3.94372268
3Macroorchidism (HP:0000053)2.95794596
4Ankyloglossia (HP:0010296)2.93807563
5Syringomyelia (HP:0003396)2.90503205
6Spinal cord lesions (HP:0100561)2.90503205
7Mesomelia (HP:0003027)2.81346283
8Thyroid carcinoma (HP:0002890)2.65972820
9Subacute progressive viral hepatitis (HP:0006572)2.65458821
10Abnormality of the nasal septum (HP:0000419)2.59399880
11Curly hair (HP:0002212)2.51075383
12Heterotopia (HP:0002282)2.49727881
13Sandal gap (HP:0001852)2.43131808
14Relative macrocephaly (HP:0004482)2.38397398
15Transitional cell carcinoma of the bladder (HP:0006740)2.36978588
16Deep philtrum (HP:0002002)2.36970805
17Truncal obesity (HP:0001956)2.36955729
18Arterial tortuosity (HP:0005116)2.34349128
19Atrophic scars (HP:0001075)2.34073040
20Abnormality of the fingertips (HP:0001211)2.34012952
21Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)2.31830528
22Abnormality of chromosome segregation (HP:0002916)2.30413354
23Absent eyebrow (HP:0002223)2.27924438
24Menstrual irregularities (HP:0000858)2.27768593
25Abnormality of oral frenula (HP:0000190)2.26220064
26Bladder carcinoma (HP:0002862)2.24569301
27Bladder neoplasm (HP:0009725)2.24569301
28Narrow palate (HP:0000189)2.23256486
29Morphological abnormality of the middle ear (HP:0008609)2.21175519
30Asymmetry of the thorax (HP:0001555)2.20088671
31Germ cell neoplasia (HP:0100728)2.16055934
32Short 4th metacarpal (HP:0010044)2.16033883
33Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.16033883
34Cubitus valgus (HP:0002967)2.14850905
35Hereditary nonpolyposis colorectal carcinoma (HP:0006716)2.13997037
36Abnormality of the distal phalanx of the thumb (HP:0009617)2.11275647
37Dislocated radial head (HP:0003083)2.10983595
38Natal tooth (HP:0000695)2.07818490
39Overgrowth (HP:0001548)2.06868908
40Coarse hair (HP:0002208)2.06598291
41Abnormality of the left ventricular outflow tract (HP:0011103)2.05120635
42Subaortic stenosis (HP:0001682)2.05120635
43Short middle phalanx of the 5th finger (HP:0004220)2.04552121
44Cystic hygroma (HP:0000476)2.04449117
45Flat acetabular roof (HP:0003180)2.04420704
46Milia (HP:0001056)2.03035130
47Preauricular pit (HP:0004467)2.02859852
48Periauricular skin pits (HP:0100277)2.02859852
49Volvulus (HP:0002580)2.02341526
50Low anterior hairline (HP:0000294)2.02177910
51Dysmetric saccades (HP:0000641)2.00401461
52Abnormality of incisor morphology (HP:0011063)1.98993846
53Leiomyosarcoma (HP:0100243)1.98313421
54Uterine leiomyosarcoma (HP:0002891)1.98313421
55Intestinal atresia (HP:0011100)1.97676940
56Vascular tortuosity (HP:0004948)1.97611576
57Blue irides (HP:0000635)1.96538340
58Gastrointestinal carcinoma (HP:0002672)1.96524799
59Malignant gastrointestinal tract tumors (HP:0006749)1.96524799
60Osteolytic defects of the hand bones (HP:0009699)1.95878457
61Osteolytic defects of the phalanges of the hand (HP:0009771)1.95878457
62Termporal pattern (HP:0011008)1.94690486
63Insidious onset (HP:0003587)1.94690486
64Overlapping toe (HP:0001845)1.94143312
65Ectopic kidney (HP:0000086)1.94125393
66Viral hepatitis (HP:0006562)1.94046557
67Abnormality of the radial head (HP:0003995)1.91281210
68Supernumerary ribs (HP:0005815)1.89809717
69Spondylolisthesis (HP:0003302)1.89799871
70Vertebral arch anomaly (HP:0008438)1.89475733
71Mitral valve prolapse (HP:0001634)1.88686578
72Skin pits (HP:0100276)1.88495920
73Anal stenosis (HP:0002025)1.86257375
74Cutaneous finger syndactyly (HP:0010554)1.83507780
75Cervical subluxation (HP:0003308)1.83088333
76Broad palm (HP:0001169)1.82331401
77Abnormality of the ischium (HP:0003174)1.82146163
78Short middle phalanx of finger (HP:0005819)1.81473799
79Large earlobe (HP:0009748)1.81407605
80Abnormality of the fetal cardiovascular system (HP:0010948)1.81072810
81Abnormal umbilical cord blood vessels (HP:0011403)1.81072810
82Single umbilical artery (HP:0001195)1.81072810
83Cutaneous syndactyly (HP:0012725)1.80622736
84Abnormality of the parietal bone (HP:0002696)1.80580515
85Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.80407436
86Gastrointestinal atresia (HP:0002589)1.79147056
87Abnormality of the epiphyses of the phalanges of the hand (HP:0005920)1.78767139
88Hypoplastic labia majora (HP:0000059)1.78655019
89Follicular hyperkeratosis (HP:0007502)1.78367663
90Aortic aneurysm (HP:0004942)1.77509066
91Long eyelashes (HP:0000527)1.77173590
92Midline defect of the nose (HP:0004122)1.77081112
93Stenosis of the external auditory canal (HP:0000402)1.76655917
94Cupped ear (HP:0000378)1.76055974
95Aplasia cutis congenita (HP:0001057)1.75770082
96Sparse lateral eyebrow (HP:0005338)1.75235049
97Vitreoretinal degeneration (HP:0000655)1.74904643
98Broad metatarsal (HP:0001783)1.74587798
99Right ventricular cardiomyopathy (HP:0011663)1.74391530
100Hypoplastic ischia (HP:0003175)1.74389668
101Epiphyseal dysplasia (HP:0002656)1.73751247
102Neoplasm of the tracheobronchial system (HP:0100552)1.72496114
103Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.72081081
104Shallow orbits (HP:0000586)1.72065823
105Dilatation of the ascending aorta (HP:0005111)1.71873191
106Abnormality of the incisor (HP:0000676)1.71797370
107Trigonocephaly (HP:0000243)1.71487089
108White forelock (HP:0002211)1.71366636
109Esophageal atresia (HP:0002032)1.70576254
110Abnormal foot bone ossification (HP:0010675)1.70327660
111Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.70259422
112Distal lower limb muscle weakness (HP:0009053)1.70205488
113Fatigue (HP:0012378)1.70158064
114Deviation of the thumb (HP:0009603)1.69947184
115Obsessive-compulsive behavior (HP:0000722)1.68872653
116Long clavicles (HP:0000890)1.68159252
117Aplasia involving bones of the upper limbs (HP:0009823)1.67806999
118Aplasia of the phalanges of the hand (HP:0009802)1.67806999
119Aplasia involving bones of the extremities (HP:0009825)1.67806999
120Abnormal pancreas size (HP:0012094)1.67462949
121Persistence of primary teeth (HP:0006335)1.67255636
122Alveolar cell carcinoma (HP:0006519)1.66540807
123Renal cell carcinoma (HP:0005584)1.66075643
124Long palpebral fissure (HP:0000637)1.65802311
125Stomach cancer (HP:0012126)1.65258406
126Absent frontal sinuses (HP:0002688)1.64843844
127Thickened calvaria (HP:0002684)1.64463741
128Supernumerary bones of the axial skeleton (HP:0009144)1.63473158
129Abnormality of the phalanges of the 5th finger (HP:0004213)1.63385642
130Thoracolumbar scoliosis (HP:0002944)1.63305598
131Tubulointerstitial nephritis (HP:0001970)1.63263125
132Cerebral aneurysm (HP:0004944)1.63005315
133Aortic dissection (HP:0002647)1.62944243
134Spontaneous hematomas (HP:0007420)1.62796262
135Premature rupture of membranes (HP:0001788)1.62783554
136Colon cancer (HP:0003003)1.62425610
137Acute lymphatic leukemia (HP:0006721)1.61994797
138Onycholysis (HP:0001806)1.61959875
139Ectropion (HP:0000656)1.60606354
140Neonatal hypoglycemia (HP:0001998)1.60401068
141Abnormality of the epiphyses of the hand (HP:0005924)1.59933762
142Testicular neoplasm (HP:0010788)1.59250881
143Synostosis of carpal bones (HP:0005048)1.58772007
144Pancreatic islet-cell hyperplasia (HP:0004510)1.58540752
145Aneurysm (HP:0002617)1.58496660
146Broad toe (HP:0001837)1.58418455
147Abnormality of the phalanges of the 2nd finger (HP:0009541)1.58007631
148Abnormality of the labia majora (HP:0012881)1.57711780
149Hypopigmentation of the fundus (HP:0007894)1.56994018
150Abnormality of the distal phalanges of the toes (HP:0010182)1.56982167
151Nephroblastoma (Wilms tumor) (HP:0002667)1.56898937
152Abnormality of the frontal sinuses (HP:0002687)1.56725390
153Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.56389035
154Blepharitis (HP:0000498)1.56126896
155Flattened epiphyses (HP:0003071)1.56023876
156Prominent nose (HP:0000448)1.55759534
157Acute myeloid leukemia (HP:0004808)1.55420855
158Rhabdomyosarcoma (HP:0002859)1.55288117
159Abnormality of the nasolacrimal system (HP:0000614)1.55175115
160Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.55030896
161Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.54184549
162Abnormality of dentin (HP:0010299)1.53916046
163Abnormality of the phalanges of the hallux (HP:0010057)1.53002209
164Abnormality of the lacrimal duct (HP:0011481)1.52641180
165Thick eyebrow (HP:0000574)1.50685791
166Short hallux (HP:0010109)1.50495521
167Skull defect (HP:0001362)1.49557913
168Short chin (HP:0000331)1.49449785
169Hamartoma (HP:0010566)1.49326057
170Down-sloping shoulders (HP:0200021)1.49067295
171Rib fusion (HP:0000902)1.48808147
172Broad thumb (HP:0011304)1.48807318
173Neoplasm of the thyroid gland (HP:0100031)1.48722318
174Colitis (HP:0002583)1.48191582
175Mild short stature (HP:0003502)1.46604728
176Embryonal renal neoplasm (HP:0011794)1.46514213
177Advanced eruption of teeth (HP:0006288)1.46293517
178Submucous cleft hard palate (HP:0000176)1.45890380
179Mixed hearing impairment (HP:0000410)1.45750091
180Pulmonic stenosis (HP:0001642)1.45162912
181Missing ribs (HP:0000921)1.44663893
182Hypoplasia of the maxilla (HP:0000327)1.43657707

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS12.82946960
2ERBB32.72311930
3MAP3K142.47601240
4EEF2K2.45520118
5MAP3K32.29531831
6MAP3K22.27408632
7NUAK12.24569565
8NLK2.22801205
9CDK122.18412861
10EPHA32.06596843
11ZAK2.00998900
12AKT31.97259101
13BRD41.84507913
14INSRR1.80891197
15TRIB31.79287459
16TRPM71.71926247
17SCYL21.71781147
18PASK1.70910835
19RIPK11.70239634
20STK241.69809509
21STK38L1.67792435
22MKNK21.58588311
23PKN21.57827714
24MKNK11.56080112
25PTK61.53586772
26FGFR21.47533249
27TGFBR21.43515407
28CAMK1G1.41363633
29FER1.40371454
30STK31.34328187
31KSR11.33600257
32BRSK21.33531606
33KSR21.32350873
34RET1.29032375
35SGK21.28360271
36CHUK1.27386494
37TIE11.20759276
38PNCK1.19288757
39TGFBR11.16107220
40EPHB11.14761078
41BMPR21.11976919
42ITK1.11969969
43MST1R1.07668858
44CLK11.06115957
45MST41.05976268
46FRK1.04361173
47STK101.02096291
48PDGFRA1.00507287
49MTOR0.99116069
50MAP3K60.97456168
51PDGFRB0.96520361
52MELK0.96383709
53CDK30.96217141
54DDR20.95315095
55FGFR10.94452629
56EIF2AK30.94426311
57FGFR40.93642086
58MAP3K70.93022236
59EPHB20.90575549
60TYK20.89780648
61CDK60.89678856
62FGFR30.89451973
63MAPK70.87543660
64SIK30.87502065
65EPHA20.86941714
66NEK60.86939110
67NEK90.86342188
68TAOK20.86174774
69BTK0.85637682
70CSNK1A1L0.85104075
71JAK20.85001036
72RPS6KA40.84731133
73CDK90.83989706
74MAP3K130.81456222
75PTK20.79880650
76MAP2K30.79814913
77STK380.79337560
78RPS6KB10.77870856
79JAK30.77499494
80IRAK10.76290563
81MARK30.75064460
82IRAK30.74235036
83ZAP700.73814294
84PIM10.73793344
85SGK30.71438696
86HIPK20.71344980
87PRKD20.71154220
88RPS6KB20.70915637
89SRPK10.70884956
90WNK10.70021934
91ATR0.69575990
92RPS6KC10.69530194
93RPS6KL10.69530194
94EIF2AK10.69522970
95CAMK1D0.69276297
96CDK70.69038802
97IKBKB0.68785997
98ICK0.68756298
99DMPK0.67818572
100IRAK40.67593524
101ATM0.67024728
102RPS6KA20.66757236
103PRPF4B0.66622919
104ERN10.65989165
105MAP4K10.63603628
106TTK0.62885625
107PRKAA20.62497634
108MAPK100.62447120
109RPS6KA60.61540981
110CDC42BPA0.61056636
111TEC0.59875013
112PIM20.59283247
113FLT30.59068876
114TAF10.58426400
115MAP3K100.58336324
116TSSK60.57899743
117PIK3CG0.57831892
118LATS20.57804276
119GRK10.57089777
120MAPKAPK20.56934697
121MET0.55786850
122MAP2K20.55140495
123CDK40.54472540
124JAK10.54102635
125MAPK110.53866352
126TXK0.53852069
127RAF10.53807949
128MARK20.53616245
129HCK0.52876522
130SGK10.52633230
131PLK30.52352795
132SGK2230.51418827
133SGK4940.51418827
134YES10.51159709
135SMG10.51016180
136STK40.50995317
137RIPK40.50620910
138NTRK30.49919991
139SIK10.49862220
140IGF1R0.49708724
141PRKCI0.47588827
142CHEK10.47394961
143CSK0.47273633
144MAP3K10.46233798

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045122.09848365
2Non-small cell lung cancer_Homo sapiens_hsa052232.01283421
3Adherens junction_Homo sapiens_hsa045201.91779591
4mTOR signaling pathway_Homo sapiens_hsa041501.83235031
5Dorso-ventral axis formation_Homo sapiens_hsa043201.83123511
6NF-kappa B signaling pathway_Homo sapiens_hsa040641.79804035
7Maturity onset diabetes of the young_Homo sapiens_hsa049501.74055103
8Basal cell carcinoma_Homo sapiens_hsa052171.72674686
9TGF-beta signaling pathway_Homo sapiens_hsa043501.67111063
10Renal cell carcinoma_Homo sapiens_hsa052111.62985509
11Phosphatidylinositol signaling system_Homo sapiens_hsa040701.61950466
12Inositol phosphate metabolism_Homo sapiens_hsa005621.61469047
13Transcriptional misregulation in cancer_Homo sapiens_hsa052021.57449855
14MicroRNAs in cancer_Homo sapiens_hsa052061.54980368
15Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.54653377
16Glioma_Homo sapiens_hsa052141.53278885
17mRNA surveillance pathway_Homo sapiens_hsa030151.52785434
18Prostate cancer_Homo sapiens_hsa052151.47780109
19Hippo signaling pathway_Homo sapiens_hsa043901.47166596
20Protein export_Homo sapiens_hsa030601.45083675
21ErbB signaling pathway_Homo sapiens_hsa040121.45016761
22Small cell lung cancer_Homo sapiens_hsa052221.42659019
23Non-homologous end-joining_Homo sapiens_hsa034501.42516940
24Focal adhesion_Homo sapiens_hsa045101.39074028
25Choline metabolism in cancer_Homo sapiens_hsa052311.34608967
26Thyroid cancer_Homo sapiens_hsa052161.32644821
27Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.28673208
28Hematopoietic cell lineage_Homo sapiens_hsa046401.26366712
29Herpes simplex infection_Homo sapiens_hsa051681.25183934
30HTLV-I infection_Homo sapiens_hsa051661.24935909
31Fanconi anemia pathway_Homo sapiens_hsa034601.22122182
32Proteoglycans in cancer_Homo sapiens_hsa052051.21510628
33Lysine degradation_Homo sapiens_hsa003101.21108568
34Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.20036185
35Graft-versus-host disease_Homo sapiens_hsa053321.19220029
36Longevity regulating pathway - mammal_Homo sapiens_hsa042111.17682655
37Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.17598129
38Hedgehog signaling pathway_Homo sapiens_hsa043401.16107437
39Leukocyte transendothelial migration_Homo sapiens_hsa046701.15161689
40Neurotrophin signaling pathway_Homo sapiens_hsa047221.13603243
41TNF signaling pathway_Homo sapiens_hsa046681.13344981
42Spliceosome_Homo sapiens_hsa030401.12827902
43Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.12599541
44RNA degradation_Homo sapiens_hsa030181.11402671
45Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.09344692
46Homologous recombination_Homo sapiens_hsa034401.08692395
47VEGF signaling pathway_Homo sapiens_hsa043701.07686852
48Insulin signaling pathway_Homo sapiens_hsa049101.07473155
49Jak-STAT signaling pathway_Homo sapiens_hsa046301.06465677
50Notch signaling pathway_Homo sapiens_hsa043301.06280388
51Phospholipase D signaling pathway_Homo sapiens_hsa040721.05744697
52Toxoplasmosis_Homo sapiens_hsa051451.05175926
53Wnt signaling pathway_Homo sapiens_hsa043101.04393931
54Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.02741015
55Base excision repair_Homo sapiens_hsa034101.02522774
56Antigen processing and presentation_Homo sapiens_hsa046121.01905417
57Pathways in cancer_Homo sapiens_hsa052001.01869757
58Primary immunodeficiency_Homo sapiens_hsa053401.00954970
59Estrogen signaling pathway_Homo sapiens_hsa049151.00830882
60Circadian rhythm_Homo sapiens_hsa047101.00711229
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.99959069
62PI3K-Akt signaling pathway_Homo sapiens_hsa041510.99856516
63Measles_Homo sapiens_hsa051620.98408004
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.98163097
65Type II diabetes mellitus_Homo sapiens_hsa049300.97584751
66Intestinal immune network for IgA production_Homo sapiens_hsa046720.97107109
67GnRH signaling pathway_Homo sapiens_hsa049120.94618922
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.94095763
69Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.94084979
70Central carbon metabolism in cancer_Homo sapiens_hsa052300.93303170
71p53 signaling pathway_Homo sapiens_hsa041150.92929681
72Viral myocarditis_Homo sapiens_hsa054160.91896389
73Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.90343419
74Chronic myeloid leukemia_Homo sapiens_hsa052200.88993230
75Cell cycle_Homo sapiens_hsa041100.88904512
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.87649885
77Tight junction_Homo sapiens_hsa045300.87183345
78Long-term potentiation_Homo sapiens_hsa047200.87142432
79Protein digestion and absorption_Homo sapiens_hsa049740.86069797
80Sphingolipid signaling pathway_Homo sapiens_hsa040710.85269153
81FoxO signaling pathway_Homo sapiens_hsa040680.84634312
82AMPK signaling pathway_Homo sapiens_hsa041520.83066557
83Hepatitis C_Homo sapiens_hsa051600.82694596
84Malaria_Homo sapiens_hsa051440.82507592
85Hepatitis B_Homo sapiens_hsa051610.82050657
86Leishmaniasis_Homo sapiens_hsa051400.82040571
87HIF-1 signaling pathway_Homo sapiens_hsa040660.81695109
88Mismatch repair_Homo sapiens_hsa034300.79610679
89Viral carcinogenesis_Homo sapiens_hsa052030.79520866
90Amoebiasis_Homo sapiens_hsa051460.79294574
91Influenza A_Homo sapiens_hsa051640.77370989
92Insulin resistance_Homo sapiens_hsa049310.75254005
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.75211130
94Toll-like receptor signaling pathway_Homo sapiens_hsa046200.72641544
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.72417280
96Pancreatic cancer_Homo sapiens_hsa052120.72407930
97Osteoclast differentiation_Homo sapiens_hsa043800.72132839
98Rap1 signaling pathway_Homo sapiens_hsa040150.70872014
99Ovarian steroidogenesis_Homo sapiens_hsa049130.69853675
100Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.69800633
101Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.69750272
102Dilated cardiomyopathy_Homo sapiens_hsa054140.69665669
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.68372801
104Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67057586
105Autoimmune thyroid disease_Homo sapiens_hsa053200.66697542
106Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66244288
107Renin secretion_Homo sapiens_hsa049240.66111443
108T cell receptor signaling pathway_Homo sapiens_hsa046600.66075398
109Melanogenesis_Homo sapiens_hsa049160.65916922
110B cell receptor signaling pathway_Homo sapiens_hsa046620.65236145
111Adipocytokine signaling pathway_Homo sapiens_hsa049200.65096690
112RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.64683447
113Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.64553952
114Long-term depression_Homo sapiens_hsa047300.64528988
115Endometrial cancer_Homo sapiens_hsa052130.63992652
116Thyroid hormone signaling pathway_Homo sapiens_hsa049190.63582499
117Melanoma_Homo sapiens_hsa052180.62415088
118Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.62106209
119Bladder cancer_Homo sapiens_hsa052190.62033485
120Apoptosis_Homo sapiens_hsa042100.61091994
121Allograft rejection_Homo sapiens_hsa053300.61076251
122Basal transcription factors_Homo sapiens_hsa030220.60047600
123Glucagon signaling pathway_Homo sapiens_hsa049220.60029536
124MAPK signaling pathway_Homo sapiens_hsa040100.60012130
125Caffeine metabolism_Homo sapiens_hsa002320.58632933
126Legionellosis_Homo sapiens_hsa051340.58530425
127Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.57374090
128Sphingolipid metabolism_Homo sapiens_hsa006000.56749416
129Acute myeloid leukemia_Homo sapiens_hsa052210.56186574
130Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56101124
131RNA transport_Homo sapiens_hsa030130.56036427
132Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.55995340
133Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.55481273
134One carbon pool by folate_Homo sapiens_hsa006700.54295183
135Ras signaling pathway_Homo sapiens_hsa040140.53332269
136Chemokine signaling pathway_Homo sapiens_hsa040620.53088031
137Steroid hormone biosynthesis_Homo sapiens_hsa001400.52474198
138Platelet activation_Homo sapiens_hsa046110.52005152
139Thyroid hormone synthesis_Homo sapiens_hsa049180.51766965
140Colorectal cancer_Homo sapiens_hsa052100.50317479
141Prolactin signaling pathway_Homo sapiens_hsa049170.49271798
142Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.48852996

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