ZC3H13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1histone H3-K4 trimethylation (GO:0080182)4.77657505
2mitotic sister chromatid cohesion (GO:0007064)4.46644676
3pre-miRNA processing (GO:0031054)4.36761631
4positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968)3.75611130
5pyrimidine nucleobase catabolic process (GO:0006208)3.70813370
6mRNA splice site selection (GO:0006376)3.68724496
7histone H3-K4 methylation (GO:0051568)3.61393009
8presynaptic membrane assembly (GO:0097105)3.60997865
9postsynaptic membrane organization (GO:0001941)3.44650077
10regulation of DNA endoreduplication (GO:0032875)3.44262504
11presynaptic membrane organization (GO:0097090)3.42611041
12peptidyl-lysine trimethylation (GO:0018023)3.33146094
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.29528265
14histone H4-K12 acetylation (GO:0043983)3.23199836
15centriole replication (GO:0007099)3.18358094
16positive regulation of dendritic spine morphogenesis (GO:0061003)3.14932437
17histone H3-K36 demethylation (GO:0070544)3.10751541
18regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.06089644
19ionotropic glutamate receptor signaling pathway (GO:0035235)3.05804383
20regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.01978800
21histone lysine methylation (GO:0034968)2.98830930
22neuron cell-cell adhesion (GO:0007158)2.96466461
23substrate-independent telencephalic tangential migration (GO:0021826)2.95261709
24substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.95261709
25neurofilament cytoskeleton organization (GO:0060052)2.93465228
26negative regulation of histone methylation (GO:0031061)2.91914495
27head development (GO:0060322)2.91687440
28histone H2B ubiquitination (GO:0033523)2.85990666
29regulation of transcription elongation from RNA polymerase II promoter (GO:0034243)2.85309968
30positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.84745862
31negative regulation of DNA-dependent DNA replication (GO:2000104)2.84602044
32nucleobase catabolic process (GO:0046113)2.83097176
33regulation of short-term neuronal synaptic plasticity (GO:0048172)2.81224903
34regulation of RNA export from nucleus (GO:0046831)2.80962477
35histone H3-K9 methylation (GO:0051567)2.78319416
36limb bud formation (GO:0060174)2.77234747
37glutamate receptor signaling pathway (GO:0007215)2.76332561
38spinal cord development (GO:0021510)2.71028887
39negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.70959583
40negative regulation of translation, ncRNA-mediated (GO:0040033)2.70959583
41regulation of translation, ncRNA-mediated (GO:0045974)2.70959583
42histone methylation (GO:0016571)2.69760417
43vocalization behavior (GO:0071625)2.67741176
44establishment of mitochondrion localization (GO:0051654)2.65193813
45regulation of glutamate receptor signaling pathway (GO:1900449)2.62096311
46regulation of nucleobase-containing compound transport (GO:0032239)2.61698658
47dendritic spine morphogenesis (GO:0060997)2.61631544
48cerebellar Purkinje cell differentiation (GO:0021702)2.60485461
49positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.60393086
50positive regulation of DNA-templated transcription, elongation (GO:0032786)2.59412205
51embryonic body morphogenesis (GO:0010172)2.58499088
52startle response (GO:0001964)2.53627988
53behavioral response to nicotine (GO:0035095)2.52750542
54monoubiquitinated protein deubiquitination (GO:0035520)2.52001423
55cerebral cortex radially oriented cell migration (GO:0021799)2.51040660
56locomotory exploration behavior (GO:0035641)2.49695767
57olfactory bulb development (GO:0021772)2.49489982
58somite development (GO:0061053)2.49402001
59regulation of histone H3-K4 methylation (GO:0051569)2.49069158
60nonmotile primary cilium assembly (GO:0035058)2.48599354
61negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.48354687
62regulation of mRNA processing (GO:0050684)2.48073053
63nuclear pore complex assembly (GO:0051292)2.47761729
64protein localization to synapse (GO:0035418)2.47586299
65synaptic vesicle docking involved in exocytosis (GO:0016081)2.47333582
66regulation of clathrin-mediated endocytosis (GO:2000369)2.47213404
67negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.46159351
68negative regulation of cell killing (GO:0031342)2.46159351
69regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.45714479
70regulation of DNA methylation (GO:0044030)2.45349330
71histone H3-K9 modification (GO:0061647)2.45218957
72positive regulation of synapse assembly (GO:0051965)2.44689593
73heart field specification (GO:0003128)2.44425427
74secondary heart field specification (GO:0003139)2.44425427
75maintenance of protein location in nucleus (GO:0051457)2.43811336
76limb development (GO:0060173)2.42779052
77appendage development (GO:0048736)2.42779052
78negative regulation of DNA recombination (GO:0045910)2.42630207
79kinetochore assembly (GO:0051382)2.42010328
80positive T cell selection (GO:0043368)2.40983759
81epithelial cilium movement (GO:0003351)2.40297034
82chromatin remodeling at centromere (GO:0031055)2.40141920
83otic vesicle formation (GO:0030916)2.40108403
84intraciliary transport (GO:0042073)2.39824504
85regulation of histone methylation (GO:0031060)2.39610496
86hindbrain development (GO:0030902)2.39420358
87specification of organ identity (GO:0010092)2.38981654
88G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.38937890
89regulation of gene silencing by RNA (GO:0060966)2.38459848
90regulation of posttranscriptional gene silencing (GO:0060147)2.38459848
91regulation of gene silencing by miRNA (GO:0060964)2.38459848
92positive regulation of gene expression, epigenetic (GO:0045815)2.38053006
93regulation of mRNA splicing, via spliceosome (GO:0048024)2.37177262
94synaptic transmission, glutamatergic (GO:0035249)2.36557732
95DNA methylation (GO:0006306)2.35937557
96DNA alkylation (GO:0006305)2.35937557
97mechanosensory behavior (GO:0007638)2.35646048
98replication fork processing (GO:0031297)2.34632534
99cytoplasmic mRNA processing body assembly (GO:0033962)2.34482222
100embryonic retina morphogenesis in camera-type eye (GO:0060059)2.34208972
101negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.33420853
102dendrite morphogenesis (GO:0048813)2.32894047
103corticosteroid receptor signaling pathway (GO:0031958)2.32688949
104glucocorticoid receptor signaling pathway (GO:0042921)2.31842545
105ncRNA catabolic process (GO:0034661)2.31689868
106central nervous system projection neuron axonogenesis (GO:0021952)2.30747315
107negative regulation of mRNA processing (GO:0050686)2.30738293
108synaptic vesicle endocytosis (GO:0048488)2.30733570
109kinetochore organization (GO:0051383)2.30710888
110retinal ganglion cell axon guidance (GO:0031290)2.30403090
111transmission of nerve impulse (GO:0019226)2.30319457
112gastrulation with mouth forming second (GO:0001702)2.30149736
113cell migration in hindbrain (GO:0021535)2.29248315
114synapse assembly (GO:0007416)2.28686378
115regulation of dendritic spine morphogenesis (GO:0061001)2.28028713
116peptidyl-lysine methylation (GO:0018022)2.27299675
117establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.26818496
118mitochondrion transport along microtubule (GO:0047497)2.26818496
119layer formation in cerebral cortex (GO:0021819)2.26291195
120mRNA stabilization (GO:0048255)2.25976125
121RNA stabilization (GO:0043489)2.25976125
122mitotic chromosome condensation (GO:0007076)2.24353183
123negative regulation of catenin import into nucleus (GO:0035414)2.24259665
124positive regulation of filopodium assembly (GO:0051491)2.24105937
125cell proliferation in forebrain (GO:0021846)2.24018845
126sister chromatid cohesion (GO:0007062)2.23991686
127sympathetic nervous system development (GO:0048485)2.23550831
128regulation of telomere maintenance (GO:0032204)2.22549188
129telomere maintenance via telomerase (GO:0007004)2.22151073
130intracellular estrogen receptor signaling pathway (GO:0030520)2.21511957
131histone lysine demethylation (GO:0070076)2.21452847
132CENP-A containing nucleosome assembly (GO:0034080)2.21283814
133DNA topological change (GO:0006265)2.21139126
134lateral sprouting from an epithelium (GO:0060601)2.20998369
135positive regulation of meiosis (GO:0045836)2.20968744
136regulation of mRNA metabolic process (GO:1903311)2.20886404
137auditory behavior (GO:0031223)2.20605407
138positive thymic T cell selection (GO:0045059)2.20487403
139ephrin receptor signaling pathway (GO:0048013)2.20207384
140axonal fasciculation (GO:0007413)2.20132225
141neuron recognition (GO:0008038)2.20096199
142histone exchange (GO:0043486)2.19652750
143microtubule organizing center organization (GO:0031023)2.19243533
144dendrite development (GO:0016358)2.19138942
145insulin-like growth factor receptor signaling pathway (GO:0048009)2.18718296
146positive regulation of meiotic cell cycle (GO:0051446)2.17666627
147positive regulation of histone H3-K4 methylation (GO:0051571)2.17494335
148body morphogenesis (GO:0010171)2.17386872
149regulation of centriole replication (GO:0046599)2.17133643
150positive regulation of dendritic spine development (GO:0060999)2.16811367
151cell fate commitment involved in formation of primary germ layer (GO:0060795)2.16793780
152thymic T cell selection (GO:0045061)2.16706342
153protein localization to chromosome, centromeric region (GO:0071459)2.16628982
154behavioral defense response (GO:0002209)2.16466649
155behavioral fear response (GO:0001662)2.16466649
156regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.16435136
157neuronal stem cell maintenance (GO:0097150)2.16073996
158protein-DNA complex disassembly (GO:0032986)2.15526753
159nucleosome disassembly (GO:0006337)2.15526753
160histone monoubiquitination (GO:0010390)2.15285936
161organ growth (GO:0035265)2.14974351
162gamma-aminobutyric acid transport (GO:0015812)2.12283575
163DNA replication checkpoint (GO:0000076)2.10952878
164regulation of growth hormone secretion (GO:0060123)2.10029489
165negative regulation of astrocyte differentiation (GO:0048712)2.09468145
166ATP-dependent chromatin remodeling (GO:0043044)2.08999822
167centrosome organization (GO:0051297)2.08127131
168adult walking behavior (GO:0007628)2.06417854
169regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.06325505
170regulation of mitotic spindle checkpoint (GO:1903504)2.06325505
171establishment of protein localization to mitochondrial membrane (GO:0090151)2.06264024

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.33558994
2RBPJ_22232070_ChIP-Seq_NCS_Mouse3.68518758
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.27870494
4TP63_19390658_ChIP-ChIP_HaCaT_Human3.09639207
5BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.85269371
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.42896602
7FOXM1_23109430_ChIP-Seq_U2OS_Human2.41994915
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.35511664
9IKZF1_21737484_ChIP-ChIP_HCT116_Human2.23708002
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.22008295
11RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.20592201
12GBX2_23144817_ChIP-Seq_PC3_Human2.18906552
13TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.16406050
14EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.02538471
15IGF1R_20145208_ChIP-Seq_DFB_Human2.01900753
16EZH2_27304074_Chip-Seq_ESCs_Mouse1.98650880
17CBX2_27304074_Chip-Seq_ESCs_Mouse1.98481207
18STAT6_21828071_ChIP-Seq_BEAS2B_Human1.97763903
19RARB_27405468_Chip-Seq_BRAIN_Mouse1.90365759
20HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.88863519
21* EWS_26573619_Chip-Seq_HEK293_Human1.88361257
22RNF2_18974828_ChIP-Seq_MESCs_Mouse1.84808788
23EZH2_18974828_ChIP-Seq_MESCs_Mouse1.84808788
24TP53_16413492_ChIP-PET_HCT116_Human1.81706883
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.80188675
26* P300_19829295_ChIP-Seq_ESCs_Human1.76921855
27ZNF274_21170338_ChIP-Seq_K562_Hela1.71147897
28ZFP281_27345836_Chip-Seq_ESCs_Mouse1.70504706
29SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.67825654
30SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.66676231
31RNF2_27304074_Chip-Seq_ESCs_Mouse1.65547401
32DROSHA_22980978_ChIP-Seq_HELA_Human1.63567597
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61255756
34P53_22127205_ChIP-Seq_FIBROBLAST_Human1.60918041
35GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59463336
36KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.58542042
37VDR_22108803_ChIP-Seq_LS180_Human1.58459102
38SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.57418364
39FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.52904804
40POU5F1_16153702_ChIP-ChIP_HESCs_Human1.52591573
41SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.52476557
42JARID2_20075857_ChIP-Seq_MESCs_Mouse1.48408397
43VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.47887410
44CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.45670581
45EGR1_19374776_ChIP-ChIP_THP-1_Human1.45123118
46PIAS1_25552417_ChIP-Seq_VCAP_Human1.44511711
47PKCTHETA_26484144_Chip-Seq_BREAST_Human1.44368338
48FUS_26573619_Chip-Seq_HEK293_Human1.43123168
49MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.42890641
50TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40154442
51RING1B_27294783_Chip-Seq_NPCs_Mouse1.40010031
52TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.39750062
53TCF4_18268006_ChIP-ChIP_LS174T_Human1.37663861
54* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.36908889
55* REST_21632747_ChIP-Seq_MESCs_Mouse1.36784946
56KDM2B_26808549_Chip-Seq_K562_Human1.36340093
57AR_21572438_ChIP-Seq_LNCaP_Human1.36119093
58* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.35125180
59E2F4_17652178_ChIP-ChIP_JURKAT_Human1.34779292
60TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.34501576
61TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.34087634
62GATA1_26923725_Chip-Seq_HPCs_Mouse1.33654745
63MTF2_20144788_ChIP-Seq_MESCs_Mouse1.33605858
64CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.33423029
65DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.32635148
66AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32237101
67SMAD4_21799915_ChIP-Seq_A2780_Human1.31881010
68KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.31780819
69SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.31713755
70AR_19668381_ChIP-Seq_PC3_Human1.31496035
71EZH2_27294783_Chip-Seq_ESCs_Mouse1.30984670
72KDM2B_26808549_Chip-Seq_JURKAT_Human1.30612538
73YAP1_20516196_ChIP-Seq_MESCs_Mouse1.30360923
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.28304599
75KDM2B_26808549_Chip-Seq_DND41_Human1.28108215
76SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.27604669
77TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26477915
78SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.26275941
79PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25981128
80RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.25416002
81STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.23605800
82TAF15_26573619_Chip-Seq_HEK293_Human1.23364040
83ISL1_27105846_Chip-Seq_CPCs_Mouse1.23130490
84RNF2_27304074_Chip-Seq_NSC_Mouse1.22815049
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22812943
86SOX9_26525672_Chip-Seq_HEART_Mouse1.22611248
87* STAT3_23295773_ChIP-Seq_U87_Human1.21044938
88KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.20692798
89E2F7_22180533_ChIP-Seq_HELA_Human1.20614050
90SUZ12_27294783_Chip-Seq_ESCs_Mouse1.20289940
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19843459
92TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19843459
93EED_16625203_ChIP-ChIP_MESCs_Mouse1.18942535
94GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.18898482
95SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.17909314
96UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.15764714
97SMAD3_21741376_ChIP-Seq_EPCs_Human1.15743756
98* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15613747
99CBP_20019798_ChIP-Seq_JUKART_Human1.15284712
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15284712
101SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.14772971
102CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13947969
103LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13637249
104PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.12694854
105SALL1_21062744_ChIP-ChIP_HESCs_Human1.12164829
106SMAD3_21741376_ChIP-Seq_ESCs_Human1.11346581
107MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.10254083
108* TCF4_23295773_ChIP-Seq_U87_Human1.09997168
109GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.09553842
110RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09426767
111RING1B_27294783_Chip-Seq_ESCs_Mouse1.09122116
112CTBP1_25329375_ChIP-Seq_LNCAP_Human1.08896069
113EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.08866858
114HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.08785452
115WDR5_24793694_ChIP-Seq_LNCAP_Human1.08375098
116TBX3_20139965_ChIP-Seq_MESCs_Mouse1.08163349
117RUNX2_22187159_ChIP-Seq_PCA_Human1.07818663
118TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07543160
119TBX3_20139965_ChIP-Seq_ESCs_Mouse1.07171833
120AR_25329375_ChIP-Seq_VCAP_Human1.07123375
121KDM2B_26808549_Chip-Seq_SUP-B15_Human1.06271607
122TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.06249807
123AHR_22903824_ChIP-Seq_MCF-7_Human1.05607318
124YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.05355897
125SMAD3_21741376_ChIP-Seq_HESCs_Human1.05251949
126WT1_19549856_ChIP-ChIP_CCG9911_Human1.04415673
127CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.03735841
128SOX2_16153702_ChIP-ChIP_HESCs_Human1.03200231
129SOX2_21211035_ChIP-Seq_LN229_Gbm1.01541129
130MYC_18940864_ChIP-ChIP_HL60_Human1.01333867
131PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00970882
132CTNNB1_20460455_ChIP-Seq_HCT116_Human1.00935598
133E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.00883365
134ARNT_22903824_ChIP-Seq_MCF-7_Human1.00592421
135ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00297090
136* BMI1_23680149_ChIP-Seq_NPCS_Mouse0.98995449
137FLI1_27457419_Chip-Seq_LIVER_Mouse0.98050835
138TBL1_22424771_ChIP-Seq_293T_Human0.97282808
139* RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.96083862
140CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96044269
141MYC_22102868_ChIP-Seq_BL_Human0.96031975
142POU3F2_20337985_ChIP-ChIP_501MEL_Human0.94608157
143STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.93408655
144NANOG_18555785_Chip-Seq_ESCs_Mouse0.92894488
145NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.92670291
146REST_18959480_ChIP-ChIP_MESCs_Mouse0.92386435
147ZFP281_18757296_ChIP-ChIP_E14_Mouse0.91758361

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.75428227
2MP0003787_abnormal_imprinting3.72300715
3MP0006292_abnormal_olfactory_placode3.09440617
4MP0005257_abnormal_intraocular_pressure2.53645688
5MP0000569_abnormal_digit_pigmentation2.51925371
6MP0008877_abnormal_DNA_methylation2.37632243
7MP0003121_genomic_imprinting2.32911460
8MP0002938_white_spotting2.21067843
9MP0003136_yellow_coat_color2.18362812
10MP0003635_abnormal_synaptic_transmissio2.14345852
11MP0002163_abnormal_gland_morphology2.10570355
12MP0001849_ear_inflammation1.94880005
13MP0005076_abnormal_cell_differentiation1.94168989
14MP0003123_paternal_imprinting1.84904110
15MP0005171_absent_coat_pigmentation1.81658525
16MP0003111_abnormal_nucleus_morphology1.76791318
17MP0004185_abnormal_adipocyte_glucose1.76687868
18MP0003693_abnormal_embryo_hatching1.72473640
19MP0002063_abnormal_learning/memory/cond1.72240133
20MP0001188_hyperpigmentation1.71433012
21MP0003880_abnormal_central_pattern1.70046931
22MP0004270_analgesia1.69824349
23MP0001293_anophthalmia1.68742871
24MP0000372_irregular_coat_pigmentation1.64319988
25MP0001984_abnormal_olfaction1.60819394
26MP0000566_synostosis1.58954433
27MP0004142_abnormal_muscle_tone1.55706004
28MP0004133_heterotaxia1.53511992
29MP0001529_abnormal_vocalization1.52074254
30MP0001346_abnormal_lacrimal_gland1.51944333
31MP0003122_maternal_imprinting1.51621353
32MP0002102_abnormal_ear_morphology1.50324325
33MP0002572_abnormal_emotion/affect_behav1.48980147
34MP0003385_abnormal_body_wall1.43130751
35MP0006276_abnormal_autonomic_nervous1.42406582
36MP0009745_abnormal_behavioral_response1.42392903
37MP0005377_hearing/vestibular/ear_phenot1.41064200
38MP0003878_abnormal_ear_physiology1.41064200
39MP0004510_myositis1.39087656
40MP0002084_abnormal_developmental_patter1.35902812
41MP0000778_abnormal_nervous_system1.35805236
42MP0003938_abnormal_ear_development1.34710744
43MP0001486_abnormal_startle_reflex1.31336075
44MP0002064_seizures1.29560400
45MP0001299_abnormal_eye_distance/1.28390883
46MP0003755_abnormal_palate_morphology1.27957094
47MP0003937_abnormal_limbs/digits/tail_de1.25298218
48MP0003861_abnormal_nervous_system1.24374876
49MP0006072_abnormal_retinal_apoptosis1.23354318
50MP0005379_endocrine/exocrine_gland_phen1.21464317
51MP0002751_abnormal_autonomic_nervous1.19231129
52MP0005187_abnormal_penis_morphology1.18892802
53MP0009046_muscle_twitch1.18683768
54MP0002735_abnormal_chemical_nociception1.18286510
55MP0001485_abnormal_pinna_reflex1.17765750
56MP0000428_abnormal_craniofacial_morphol1.16850536
57MP0002067_abnormal_sensory_capabilities1.16768268
58MP0002095_abnormal_skin_pigmentation1.16312991
59MP0004742_abnormal_vestibular_system1.13721844
60MP0008057_abnormal_DNA_replication1.13387163
61MP0002752_abnormal_somatic_nervous1.12214467
62MP0003890_abnormal_embryonic-extraembry1.12199419
63MP0001286_abnormal_eye_development1.11774165
64MP0002736_abnormal_nociception_after1.11354658
65MP0008961_abnormal_basal_metabolism1.10965412
66MP0003935_abnormal_craniofacial_develop1.10694943
67MP0008058_abnormal_DNA_repair1.09537815
68MP0003119_abnormal_digestive_system1.08872324
69MP0000049_abnormal_middle_ear1.08207380
70MP0003303_peritoneal_inflammation1.08069603
71MP0002184_abnormal_innervation1.06067236
72MP0008789_abnormal_olfactory_epithelium1.03800481
73MP0000432_abnormal_head_morphology1.03238982
74MP0003567_abnormal_fetal_cardiomyocyte1.03149210
75MP0002822_catalepsy1.02924271
76MP0002638_abnormal_pupillary_reflex1.00542484
77MP0010030_abnormal_orbit_morphology1.00424750
78MP0002152_abnormal_brain_morphology0.99612240
79MP0003984_embryonic_growth_retardation0.99350896
80MP0005551_abnormal_eye_electrophysiolog0.99320918
81MP0002085_abnormal_embryonic_tissue0.99289010
82MP0001672_abnormal_embryogenesis/_devel0.99249073
83MP0005380_embryogenesis_phenotype0.99249073
84MP0009780_abnormal_chondrocyte_physiolo0.98972879
85MP0002116_abnormal_craniofacial_bone0.98715020
86MP0000750_abnormal_muscle_regeneration0.97872269
87MP0004885_abnormal_endolymph0.97728095
88MP0002088_abnormal_embryonic_growth/wei0.96516981
89MP0000631_abnormal_neuroendocrine_gland0.96454998
90MP0001440_abnormal_grooming_behavior0.96193666
91MP0005174_abnormal_tail_pigmentation0.94901608
92MP0001730_embryonic_growth_arrest0.94757186
93MP0003283_abnormal_digestive_organ0.94662530
94MP0010094_abnormal_chromosome_stability0.93574055
95MP0003942_abnormal_urinary_system0.93161555
96MP0005310_abnormal_salivary_gland0.93077719
97MP0002909_abnormal_adrenal_gland0.92538637
98MP0005503_abnormal_tendon_morphology0.90630377
99MP0002734_abnormal_mechanical_nocicepti0.90482076
100MP0003077_abnormal_cell_cycle0.90317005
101MP0005408_hypopigmentation0.89900563
102MP0004924_abnormal_behavior0.89887592
103MP0005386_behavior/neurological_phenoty0.89887592
104MP0000350_abnormal_cell_proliferation0.89650429
105MP0001501_abnormal_sleep_pattern0.89466139
106MP0001851_eye_inflammation0.88651718
107MP0002882_abnormal_neuron_morphology0.88507183
108MP0002697_abnormal_eye_size0.87074136
109MP0000026_abnormal_inner_ear0.86276390
110MP0009250_abnormal_appendicular_skeleto0.84660338
111MP0002557_abnormal_social/conspecific_i0.83743962
112MP0001324_abnormal_eye_pigmentation0.83675693
113MP0000537_abnormal_urethra_morphology0.83420600
114MP0002066_abnormal_motor_capabilities/c0.83259298
115MP0005248_abnormal_Harderian_gland0.82151005
116MP0005394_taste/olfaction_phenotype0.81584142
117MP0005499_abnormal_olfactory_system0.81584142
118MP0009379_abnormal_foot_pigmentation0.80424575
119MP0000579_abnormal_nail_morphology0.80386274
120MP0004085_abnormal_heartbeat0.79985600
121MP0002234_abnormal_pharynx_morphology0.79954000
122MP0002396_abnormal_hematopoietic_system0.79570291
123MP0005253_abnormal_eye_physiology0.79020503
124MP0002081_perinatal_lethality0.78753209
125MP0002925_abnormal_cardiovascular_devel0.78435799
126MP0005423_abnormal_somatic_nervous0.78338011
127MP0002233_abnormal_nose_morphology0.78327655
128MP0002249_abnormal_larynx_morphology0.77620754
129MP0003828_pulmonary_edema0.77569983
130MP0001502_abnormal_circadian_rhythm0.76347669
131MP0000751_myopathy0.75789703
132MP0004811_abnormal_neuron_physiology0.74715326
133MP0002086_abnormal_extraembryonic_tissu0.74217405
134MP0001968_abnormal_touch/_nociception0.73757168
135MP0003045_fibrosis0.73718693
136MP0001697_abnormal_embryo_size0.73658265
137MP0000955_abnormal_spinal_cord0.73637670
138MP0002272_abnormal_nervous_system0.72441869
139MP0008770_decreased_survivor_rate0.72326680
140MP0000003_abnormal_adipose_tissue0.72087972
141MP0002114_abnormal_axial_skeleton0.71780692
142MP0004197_abnormal_fetal_growth/weight/0.69479919

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.78972754
2Vertebral arch anomaly (HP:0008438)3.58959159
3Abnormality of the fingertips (HP:0001211)3.10331917
4Genetic anticipation (HP:0003743)3.07595292
5Lip pit (HP:0100267)3.03389003
6Abnormality of the nasal septum (HP:0000419)3.02582667
7Pancreatic fibrosis (HP:0100732)2.83255145
8Molar tooth sign on MRI (HP:0002419)2.81249389
9Abnormality of midbrain morphology (HP:0002418)2.81249389
10Oligodontia (HP:0000677)2.77189143
11Focal motor seizures (HP:0011153)2.75424222
12Abnormality of the intervertebral disk (HP:0005108)2.61887301
13Hepatoblastoma (HP:0002884)2.57604371
14Supernumerary ribs (HP:0005815)2.51169554
15Abnormality of the labia minora (HP:0012880)2.45971153
16Long eyelashes (HP:0000527)2.42952436
17Rib fusion (HP:0000902)2.37707485
18Progressive cerebellar ataxia (HP:0002073)2.33635018
19Nephronophthisis (HP:0000090)2.31026359
20Sparse scalp hair (HP:0002209)2.25406211
21Pancreatic cysts (HP:0001737)2.25399330
22Supernumerary bones of the axial skeleton (HP:0009144)2.25224389
23Facial hemangioma (HP:0000329)2.24849743
24Aplasia/Hypoplasia of the uvula (HP:0010293)2.22431043
25Abnormal hair whorl (HP:0010721)2.21061853
26Urethral obstruction (HP:0000796)2.19530674
27Shawl scrotum (HP:0000049)2.18123795
28Cortical dysplasia (HP:0002539)2.14977909
29Chromsome breakage (HP:0040012)2.12685532
30Ectopic kidney (HP:0000086)2.10589098
31Increased nuchal translucency (HP:0010880)2.07250863
32Pendular nystagmus (HP:0012043)2.06626476
33Meckel diverticulum (HP:0002245)2.05467168
34Abnormality of the tricuspid valve (HP:0001702)2.04353127
35Febrile seizures (HP:0002373)2.02109521
36Focal seizures (HP:0007359)2.01917544
37Microtia (HP:0008551)2.01693137
38Intestinal atresia (HP:0011100)2.01376198
39Aplasia cutis congenita (HP:0001057)2.00589874
40Drooling (HP:0002307)2.00235528
41Excessive salivation (HP:0003781)2.00235528
42Abnormality of chromosome stability (HP:0003220)1.99885663
43Cutaneous finger syndactyly (HP:0010554)1.99536670
44Large eyes (HP:0001090)1.99162413
45Abnormality of the ileum (HP:0001549)1.97583925
46True hermaphroditism (HP:0010459)1.95448954
47Colon cancer (HP:0003003)1.95383143
48Limited hip movement (HP:0008800)1.94762173
49Abnormality of the parietal bone (HP:0002696)1.94428818
50Hyperventilation (HP:0002883)1.94008178
51Widely spaced teeth (HP:0000687)1.92035310
52Trigonocephaly (HP:0000243)1.92000602
53Labial hypoplasia (HP:0000066)1.91359193
54Anal stenosis (HP:0002025)1.89879162
55Sparse lateral eyebrow (HP:0005338)1.89564970
56Abnormality of the renal medulla (HP:0100957)1.88830474
57Cystic liver disease (HP:0006706)1.87770668
58Anencephaly (HP:0002323)1.87485539
59Ependymoma (HP:0002888)1.87341596
60Urinary bladder sphincter dysfunction (HP:0002839)1.86699047
61Preaxial hand polydactyly (HP:0001177)1.86516574
62Astrocytoma (HP:0009592)1.85363636
63Abnormality of the astrocytes (HP:0100707)1.85363636
64Uterine leiomyosarcoma (HP:0002891)1.84416979
65Leiomyosarcoma (HP:0100243)1.84416979
66Median cleft lip (HP:0000161)1.84309168
67Narrow palate (HP:0000189)1.83249460
68Oligodactyly (HP:0012165)1.83178811
69Narrow forehead (HP:0000341)1.82545643
70Chin dimple (HP:0010751)1.82373778
71Hypoplastic female external genitalia (HP:0012815)1.81984586
72Genu recurvatum (HP:0002816)1.81406741
73Spina bifida occulta (HP:0003298)1.81198729
74Patellar aplasia (HP:0006443)1.80669292
75Limited elbow extension (HP:0001377)1.80232434
76Esophageal atresia (HP:0002032)1.78345441
77Cutaneous syndactyly (HP:0012725)1.78194731
78High anterior hairline (HP:0009890)1.77195027
79Epileptic encephalopathy (HP:0200134)1.76891094
80Gastroesophageal reflux (HP:0002020)1.76684776
81Dislocated radial head (HP:0003083)1.76476221
82Papillary thyroid carcinoma (HP:0002895)1.76246404
83Abnormality of the carotid arteries (HP:0005344)1.75788760
84Chromosomal breakage induced by crosslinking agents (HP:0003221)1.75630118
85Transitional cell carcinoma of the bladder (HP:0006740)1.75412236
86Short philtrum (HP:0000322)1.75405367
87Inappropriate behavior (HP:0000719)1.75171232
88Midline defect of the nose (HP:0004122)1.74824979
89Exotropia (HP:0000577)1.74602761
90Gastrointestinal atresia (HP:0002589)1.72947888
91Obsessive-compulsive behavior (HP:0000722)1.72868990
92Highly arched eyebrow (HP:0002553)1.72698488
93Pachygyria (HP:0001302)1.72479273
94Sleep apnea (HP:0010535)1.72250742
95Postaxial foot polydactyly (HP:0001830)1.71957141
96Bifid tongue (HP:0010297)1.70193317
97Aplasia/Hypoplasia of the sternum (HP:0006714)1.69805463
98Abnormality of the lower motor neuron (HP:0002366)1.68290865
99Supernumerary spleens (HP:0009799)1.67830278
100Abnormality of the diencephalon (HP:0010662)1.67107137
101Oligodactyly (hands) (HP:0001180)1.66888842
102Medial flaring of the eyebrow (HP:0010747)1.66865961
103Myokymia (HP:0002411)1.66690978
104Chronic hepatic failure (HP:0100626)1.66506264
105Anophthalmia (HP:0000528)1.66471149
106Short 4th metacarpal (HP:0010044)1.66434378
107Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.66434378
108Blue irides (HP:0000635)1.66100999
109Proximal placement of thumb (HP:0009623)1.65771441
110Hypoplastic ischia (HP:0003175)1.65471807
111Septo-optic dysplasia (HP:0100842)1.65369058
112Limb dystonia (HP:0002451)1.65232957
113Bladder neoplasm (HP:0009725)1.65012048
114Bladder carcinoma (HP:0002862)1.65012048
115Abnormality of the radial head (HP:0003995)1.64504740
116Protruding tongue (HP:0010808)1.64069329
117Hyperacusis (HP:0010780)1.64048927
118Gait imbalance (HP:0002141)1.62428863
119Dandy-Walker malformation (HP:0001305)1.62261896
120Genital tract atresia (HP:0001827)1.61957878
121Triphalangeal thumb (HP:0001199)1.61554697
122Abnormal lung lobation (HP:0002101)1.61165616
123Polyphagia (HP:0002591)1.60667363
124Postaxial hand polydactyly (HP:0001162)1.60601807
125Prominent nose (HP:0000448)1.60513710
126Abnormality of the phalanges of the hallux (HP:0010057)1.60472766
127Astigmatism (HP:0000483)1.60440497
128Lissencephaly (HP:0001339)1.60150239
129Cupped ear (HP:0000378)1.59982121
130Aplasia/Hypoplasia of the patella (HP:0006498)1.59344992
131Abnormality of the corticospinal tract (HP:0002492)1.59211693
132Small epiphyses (HP:0010585)1.58942061
133Broad-based gait (HP:0002136)1.58925519
134Deeply set eye (HP:0000490)1.58808291
135Rhabdomyosarcoma (HP:0002859)1.58762795
136Rectal prolapse (HP:0002035)1.58630056
137Micropenis (HP:0000054)1.58117000
138Deviation of the thumb (HP:0009603)1.58067593
139Aqueductal stenosis (HP:0002410)1.57240415
140Impulsivity (HP:0100710)1.56066088
141Broad thumb (HP:0011304)1.55581559
142Optic nerve hypoplasia (HP:0000609)1.55456807
143Poor coordination (HP:0002370)1.54986989
144Abnormality of the aortic arch (HP:0012303)1.54912164
145Dysmetric saccades (HP:0000641)1.54691375
146Bilateral microphthalmos (HP:0007633)1.54418235
147Primary atrial arrhythmia (HP:0001692)1.54108767
148Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.54057854
149Small hand (HP:0200055)1.53500673
150Thick eyebrow (HP:0000574)1.52715384
151Vaginal atresia (HP:0000148)1.52019061
152Wide intermamillary distance (HP:0006610)1.51961896
153Neoplasm of the oral cavity (HP:0100649)1.51856012
154Facial cleft (HP:0002006)1.51793456
155Abnormal number of incisors (HP:0011064)1.51672128
156Morphological abnormality of the middle ear (HP:0008609)1.49500409
157Vesicoureteral reflux (HP:0000076)1.49253790
158Patellar dislocation (HP:0002999)1.48605934
159Abnormality of the columella (HP:0009929)1.47026081
160Pointed chin (HP:0000307)1.47008025
161Smooth philtrum (HP:0000319)1.46862651
162Renal duplication (HP:0000075)1.46739012
163Absent frontal sinuses (HP:0002688)1.46618396
164Acute lymphatic leukemia (HP:0006721)1.46456769
165Skin pits (HP:0100276)1.46116940

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.75856548
2CASK3.01313836
3CDC72.95585774
4SIK22.87504649
5LATS12.74700053
6NTRK32.68657506
7TAOK12.56930612
8BRD42.52342879
9PNCK2.28624863
10LATS22.25290731
11EPHA42.22098486
12WNK32.13572868
13INSRR2.00182252
14DMPK1.96861769
15MAP3K41.89412940
16CAMK1G1.82467891
17BMPR1B1.78158860
18MARK21.71513969
19CDK81.63073868
20NTRK21.56120605
21DYRK21.55758319
22MKNK21.54148051
23RIPK41.37432213
24BCR1.36661026
25MAP3K91.34891408
26PLK31.34242017
27CAMK1D1.30439739
28TNIK1.30396653
29CHEK21.26990784
30PRKD21.26353506
31ALK1.22995104
32PRKCG1.21068877
33MARK11.20657274
34MTOR1.19895774
35STK381.18959388
36PLK11.18055176
37CSNK1E1.17749666
38WEE11.14325513
39PLK21.12488354
40WNK41.11346299
41CDC42BPA1.09931506
42MAPK131.09369595
43FGFR21.09323961
44MAP3K61.08284504
45PAK61.07441029
46PINK11.07026582
47UHMK11.02918411
48TSSK61.01099390
49CDK70.99431971
50NTRK10.98377055
51NUAK10.98125757
52SGK20.97857872
53MAPK100.96975852
54CHEK10.96465300
55NEK20.95767852
56PRPF4B0.94093445
57FRK0.92236387
58STK110.89749782
59TAF10.88899971
60STK30.88540068
61TTK0.86430469
62DAPK20.85296959
63MAP2K40.84478434
64CDK20.84421328
65NME10.83230472
66ATM0.82809253
67CSNK1G20.82287276
68CDK30.82213706
69SGK2230.81163547
70SGK4940.81163547
71MAPK140.80470923
72GSK3B0.79218142
73SIK30.79208124
74SGK10.77375256
75MINK10.76208917
76DYRK1A0.75264193
77ACVR1B0.75261865
78CAMK40.74139015
79CDK10.71346852
80TRIM280.70197804
81WNK10.69714670
82PLK40.69156669
83EPHB20.66140661
84RPS6KA30.64636995
85FES0.63855585
86MAP4K20.63813883
87PRKCH0.63045261
88EEF2K0.62493364
89CDK40.61966195
90CSNK1D0.61834663
91ICK0.61568766
92STK390.61164347
93CDK190.59715549
94SRPK10.59414574
95CDK180.58522034
96FGFR10.58510656
97CDK90.58261181
98CDK150.57992755
99MKNK10.57787550
100RAF10.57392304
101MAP3K70.57020743
102TYRO30.57009144
103STK100.56286438
104MARK30.55872511
105TAOK30.55813468
106CAMK2A0.55169678
107PKN10.54431183
108CSNK1G10.53813997
109OXSR10.53372195
110PDGFRB0.53304806
111PAK20.52427829
112PRKCE0.52146453
113PRKDC0.51777686
114AKT30.51150148
115MAPK80.50724452
116FGR0.50633429
117CDK140.50559614
118NEK10.49630483
119BRSK20.49228148
120DYRK30.49100683
121CSNK2A20.48703411
122CDK50.48521887
123CDK60.48502019
124PRKG10.48467696
125CAMK10.48426074
126CSNK1A10.47956189
127EPHA30.47480158
128PAK30.46045675
129RPS6KA10.46014681
130MAP2K70.45685844
131PRKACB0.45418373
132ERBB20.45265713
133KSR10.42653959
134STK38L0.41134354
135ERBB40.40714534
136AURKB0.40701388
137PRKCB0.40652244
138ATR0.37633378
139CDK11A0.37297322
140DAPK10.36944655
141PRKD10.36502098
142RET0.35927245
143MAPKAPK20.35836296
144MAPK90.35641982
145GRK50.35602861

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.31787356
2Protein export_Homo sapiens_hsa030602.17947370
3Mismatch repair_Homo sapiens_hsa034302.08705255
4Fanconi anemia pathway_Homo sapiens_hsa034602.06781579
5Homologous recombination_Homo sapiens_hsa034401.97371520
6Long-term potentiation_Homo sapiens_hsa047201.83004486
7Non-homologous end-joining_Homo sapiens_hsa034501.81737053
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.68789585
9Glutamatergic synapse_Homo sapiens_hsa047241.59465219
10RNA degradation_Homo sapiens_hsa030181.59394241
11Circadian entrainment_Homo sapiens_hsa047131.55237153
12Amphetamine addiction_Homo sapiens_hsa050311.44840385
13Cardiac muscle contraction_Homo sapiens_hsa042601.43731169
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.37625181
15Oxytocin signaling pathway_Homo sapiens_hsa049211.36724295
16Type II diabetes mellitus_Homo sapiens_hsa049301.31475897
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.30574397
18Olfactory transduction_Homo sapiens_hsa047401.30382553
19Morphine addiction_Homo sapiens_hsa050321.29926288
20Basal transcription factors_Homo sapiens_hsa030221.29807507
21Dopaminergic synapse_Homo sapiens_hsa047281.29087071
22mRNA surveillance pathway_Homo sapiens_hsa030151.28037970
23DNA replication_Homo sapiens_hsa030301.25687696
24Axon guidance_Homo sapiens_hsa043601.24265097
25MicroRNAs in cancer_Homo sapiens_hsa052061.23542948
26Renin secretion_Homo sapiens_hsa049241.23225486
27Wnt signaling pathway_Homo sapiens_hsa043101.22652524
28Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22375194
29Salivary secretion_Homo sapiens_hsa049701.20405098
30Glioma_Homo sapiens_hsa052141.18353221
31Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.16993365
32Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16931867
33mTOR signaling pathway_Homo sapiens_hsa041501.15763038
34cAMP signaling pathway_Homo sapiens_hsa040241.14690592
35Cholinergic synapse_Homo sapiens_hsa047251.13703004
36Calcium signaling pathway_Homo sapiens_hsa040201.13666084
37ErbB signaling pathway_Homo sapiens_hsa040121.12914131
38GABAergic synapse_Homo sapiens_hsa047271.12847330
39RNA polymerase_Homo sapiens_hsa030201.12735093
40Oxidative phosphorylation_Homo sapiens_hsa001901.12194385
41Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.11481628
42Nucleotide excision repair_Homo sapiens_hsa034201.09878698
43Spliceosome_Homo sapiens_hsa030401.09771309
44GnRH signaling pathway_Homo sapiens_hsa049121.08816226
45Parkinsons disease_Homo sapiens_hsa050121.08586775
46Long-term depression_Homo sapiens_hsa047301.08536937
47Estrogen signaling pathway_Homo sapiens_hsa049151.08154964
48Colorectal cancer_Homo sapiens_hsa052101.05325737
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.05292260
50Thyroid hormone signaling pathway_Homo sapiens_hsa049191.04647384
51Non-small cell lung cancer_Homo sapiens_hsa052231.04440777
52Base excision repair_Homo sapiens_hsa034101.03638315
53Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.03091093
54Huntingtons disease_Homo sapiens_hsa050161.02695178
55Selenocompound metabolism_Homo sapiens_hsa004501.02638925
56Cocaine addiction_Homo sapiens_hsa050301.02279547
57Dilated cardiomyopathy_Homo sapiens_hsa054141.02259464
58Insulin secretion_Homo sapiens_hsa049111.02003916
59Steroid biosynthesis_Homo sapiens_hsa001001.01497632
60Propanoate metabolism_Homo sapiens_hsa006401.01112843
61Adherens junction_Homo sapiens_hsa045201.00608796
62cGMP-PKG signaling pathway_Homo sapiens_hsa040221.00549229
63Taste transduction_Homo sapiens_hsa047420.98417803
64Serotonergic synapse_Homo sapiens_hsa047260.98141311
65T cell receptor signaling pathway_Homo sapiens_hsa046600.97461086
66Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.97311651
67Tight junction_Homo sapiens_hsa045300.96736676
68Phosphatidylinositol signaling system_Homo sapiens_hsa040700.96418467
69Lysine degradation_Homo sapiens_hsa003100.95844840
70MAPK signaling pathway_Homo sapiens_hsa040100.94886256
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.94413523
72Circadian rhythm_Homo sapiens_hsa047100.94280173
73Renal cell carcinoma_Homo sapiens_hsa052110.94132061
74Endometrial cancer_Homo sapiens_hsa052130.93950120
75One carbon pool by folate_Homo sapiens_hsa006700.93042308
76Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.92319875
77Phototransduction_Homo sapiens_hsa047440.92054863
78Choline metabolism in cancer_Homo sapiens_hsa052310.91423107
79Basal cell carcinoma_Homo sapiens_hsa052170.90882917
80Dorso-ventral axis formation_Homo sapiens_hsa043200.90866568
81Ribosome_Homo sapiens_hsa030100.90864179
82Chronic myeloid leukemia_Homo sapiens_hsa052200.90043631
83Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.89905836
84Pancreatic cancer_Homo sapiens_hsa052120.87880130
85Gastric acid secretion_Homo sapiens_hsa049710.87167279
86Melanogenesis_Homo sapiens_hsa049160.87059148
87Butanoate metabolism_Homo sapiens_hsa006500.86968128
88Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.84874202
89Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.84086576
90VEGF signaling pathway_Homo sapiens_hsa043700.83277023
91Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.83114148
92Synaptic vesicle cycle_Homo sapiens_hsa047210.82704794
93Phospholipase D signaling pathway_Homo sapiens_hsa040720.81943431
94Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.81615103
95Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.81466858
96Rap1 signaling pathway_Homo sapiens_hsa040150.81358070
97Osteoclast differentiation_Homo sapiens_hsa043800.80834669
98Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.80676368
99Hippo signaling pathway_Homo sapiens_hsa043900.80318686
100Oocyte meiosis_Homo sapiens_hsa041140.80220730
101Vascular smooth muscle contraction_Homo sapiens_hsa042700.80099578
102Gap junction_Homo sapiens_hsa045400.80048947
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.79609047
104Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.79165919
105Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.78250463
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.77882031
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.77704364
108Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77336333
109Melanoma_Homo sapiens_hsa052180.76834280
110Prostate cancer_Homo sapiens_hsa052150.76644862
111Alzheimers disease_Homo sapiens_hsa050100.76359049
112Longevity regulating pathway - mammal_Homo sapiens_hsa042110.76314206
113Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76138927
114Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.76120871
115Graft-versus-host disease_Homo sapiens_hsa053320.75776370
116Ras signaling pathway_Homo sapiens_hsa040140.75421189
117Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.74803762
118Notch signaling pathway_Homo sapiens_hsa043300.74199789
119Hedgehog signaling pathway_Homo sapiens_hsa043400.71989152
120Neurotrophin signaling pathway_Homo sapiens_hsa047220.71902573
121Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.71315347
122Prolactin signaling pathway_Homo sapiens_hsa049170.71267889
123FoxO signaling pathway_Homo sapiens_hsa040680.70081934
124RNA transport_Homo sapiens_hsa030130.69917226
125Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.69749777
126Transcriptional misregulation in cancer_Homo sapiens_hsa052020.69440777
127Proteoglycans in cancer_Homo sapiens_hsa052050.69303250
128B cell receptor signaling pathway_Homo sapiens_hsa046620.69256479
129Cysteine and methionine metabolism_Homo sapiens_hsa002700.68835818
130Chemokine signaling pathway_Homo sapiens_hsa040620.68655322
131Thyroid hormone synthesis_Homo sapiens_hsa049180.68382933
132Primary immunodeficiency_Homo sapiens_hsa053400.66719759
133Cell cycle_Homo sapiens_hsa041100.66374082
134TGF-beta signaling pathway_Homo sapiens_hsa043500.61422553
135beta-Alanine metabolism_Homo sapiens_hsa004100.55792006
136Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.51982067
137Caffeine metabolism_Homo sapiens_hsa002320.47429593
138Linoleic acid metabolism_Homo sapiens_hsa005910.44530536
139Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.38528541
140Maturity onset diabetes of the young_Homo sapiens_hsa049500.37862586
141Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37718156
142Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.37474772
143Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.36205733

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