ZC3H7A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.41648061
2antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.40231475
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.28120035
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.28120035
5antigen processing and presentation of endogenous antigen (GO:0019883)4.20138559
6positive regulation of cellular amide metabolic process (GO:0034250)4.09133990
7modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.97548797
8positive regulation by organism of defense response of other organism involved in symbiotic interact3.97548797
9modulation by symbiont of host immune response (GO:0052553)3.97548797
10positive regulation by symbiont of host defense response (GO:0052509)3.97548797
11modulation by symbiont of host defense response (GO:0052031)3.97548797
12modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.97548797
13positive regulation of granulocyte differentiation (GO:0030854)3.94565621
14positive regulation of interferon-alpha production (GO:0032727)3.90078904
15neutrophil activation involved in immune response (GO:0002283)3.81344917
16positive regulation of histone H3-K4 methylation (GO:0051571)3.76298567
17regulation of gamma-delta T cell activation (GO:0046643)3.76124622
18response to peptidoglycan (GO:0032494)3.71363292
19regulation of interferon-alpha production (GO:0032647)3.69530702
20response to muramyl dipeptide (GO:0032495)3.68752541
21NIK/NF-kappaB signaling (GO:0038061)3.63461328
22response to type I interferon (GO:0034340)3.63325197
23regulation of interleukin-12 biosynthetic process (GO:0045075)3.59483698
24cellular response to type I interferon (GO:0071357)3.59261178
25type I interferon signaling pathway (GO:0060337)3.59261178
26positive regulation of mitotic sister chromatid separation (GO:1901970)3.57114350
27positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.57114350
28positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.57114350
29regulation of histone H3-K27 methylation (GO:0061085)3.55550999
30regulation of interferon-beta biosynthetic process (GO:0045357)3.53716421
31peptidyl-lysine trimethylation (GO:0018023)3.49215278
32regulation of gamma-delta T cell differentiation (GO:0045586)3.45090193
33positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)3.37454021
34regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)3.37454021
35neutrophil activation (GO:0042119)3.36877109
36positive regulation of B cell differentiation (GO:0045579)3.36699901
37positive regulation of natural killer cell differentiation (GO:0032825)3.34619405
38regulation of RNA export from nucleus (GO:0046831)3.34414247
39T cell migration (GO:0072678)3.30437821
40regulation of RIG-I signaling pathway (GO:0039535)3.30398029
41mRNA modification (GO:0016556)3.30105234
42regulation of fibroblast apoptotic process (GO:2000269)3.25827218
43regulation of B cell receptor signaling pathway (GO:0050855)3.23689547
44histone H3-K4 methylation (GO:0051568)3.21646691
45positive regulation of antigen processing and presentation (GO:0002579)3.19515631
46positive T cell selection (GO:0043368)3.19345858
47cellular response to ethanol (GO:0071361)3.17589564
48mitotic sister chromatid cohesion (GO:0007064)3.17443936
49positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.14735546
50antigen processing and presentation via MHC class Ib (GO:0002475)3.11992464
51granulocyte activation (GO:0036230)3.11533086
52regulation of histone H3-K4 methylation (GO:0051569)3.08886282
53germinal center formation (GO:0002467)3.08458763
54interferon-gamma-mediated signaling pathway (GO:0060333)3.08359407
55response to interferon-alpha (GO:0035455)3.07957878
56regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04874540
57macrophage activation involved in immune response (GO:0002281)3.04302490
58regulation of B cell differentiation (GO:0045577)3.00967465
59negative regulation of neurotransmitter secretion (GO:0046929)2.99759286
60regulation of MHC class I biosynthetic process (GO:0045343)2.99483102
61interferon-gamma production (GO:0032609)2.98039057
62positive regulation of interferon-beta production (GO:0032728)2.97848922
63neutrophil mediated immunity (GO:0002446)2.97034398
64positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.96306197
65positive thymic T cell selection (GO:0045059)2.95220195
66regulation of alpha-beta T cell proliferation (GO:0046640)2.93797329
67defense response to protozoan (GO:0042832)2.93676496
68I-kappaB phosphorylation (GO:0007252)2.93434210
69COPII vesicle coating (GO:0048208)2.92019585
70immunoglobulin mediated immune response (GO:0016064)2.91622699
71histone H3-K4 trimethylation (GO:0080182)2.89469443
72leukocyte aggregation (GO:0070486)2.87991494
73positive regulation of interleukin-12 production (GO:0032735)2.87930241
74negative thymic T cell selection (GO:0045060)2.87646848
75B cell homeostasis (GO:0001782)2.87003943
76CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.86950263
77B cell receptor signaling pathway (GO:0050853)2.86912732
78response to host immune response (GO:0052572)2.86899472
79response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.86899472
80T-helper 1 type immune response (GO:0042088)2.85062107
81T cell homeostasis (GO:0043029)2.84651811
82regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.83754586
83negative T cell selection (GO:0043383)2.83640903
84mature B cell differentiation (GO:0002335)2.83399883
85necrotic cell death (GO:0070265)2.80358889
86negative regulation of bone resorption (GO:0045779)2.78306077
87regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.78100682
88regulation of antigen processing and presentation (GO:0002577)2.77939397
89positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.77872593
90response to protozoan (GO:0001562)2.76400449
91JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.75235529
92monoubiquitinated protein deubiquitination (GO:0035520)2.74983821
93peptidyl-lysine methylation (GO:0018022)2.74873893
94nuclear pore complex assembly (GO:0051292)2.74349146
95cellular response to interferon-beta (GO:0035458)2.73966773
96detection of other organism (GO:0098543)2.73759793
97myeloid cell activation involved in immune response (GO:0002275)2.72933385
98positive regulation of interleukin-2 production (GO:0032743)2.72391673
99negative regulation of fibroblast apoptotic process (GO:2000270)2.72227824
100natural killer cell mediated cytotoxicity (GO:0042267)2.71804321
101natural killer cell mediated immunity (GO:0002228)2.71804321
102phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.70268251
103regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.69956093
104myeloid dendritic cell activation (GO:0001773)2.69844618
105programmed necrotic cell death (GO:0097300)2.65517695
106cellular response to exogenous dsRNA (GO:0071360)2.63597712
107T-helper cell differentiation (GO:0042093)2.63417485
108CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.63417485
109necroptotic process (GO:0070266)2.63215901
110response to host (GO:0075136)2.62915399
111response to host defenses (GO:0052200)2.62915399
112response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.62915399
113histone H3-K9 demethylation (GO:0033169)2.62825525
114histone mRNA catabolic process (GO:0071044)2.62317395
115lipopolysaccharide-mediated signaling pathway (GO:0031663)2.62247495
116definitive hemopoiesis (GO:0060216)2.60735751
117B cell proliferation (GO:0042100)2.59373847
118detection of molecule of bacterial origin (GO:0032490)2.58700351
119mitochondrial DNA replication (GO:0006264)2.57756774
120regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.57380988
121histone H4-K16 acetylation (GO:0043984)2.57380326
122cytoplasmic pattern recognition receptor signaling pathway (GO:0002753)2.57257821
123respiratory burst (GO:0045730)2.56616280
124regulation of necroptotic process (GO:0060544)2.55689434
125negative regulation of histone methylation (GO:0031061)2.55244892
126regulation of T-helper 1 cell differentiation (GO:0045625)2.55120167
127T cell selection (GO:0045058)2.55066256
128JAK-STAT cascade (GO:0007259)2.54947435
129negative regulation of B cell proliferation (GO:0030889)2.54793408
130cellular extravasation (GO:0045123)2.54601775
131CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.54226848
132positive regulation of alpha-beta T cell proliferation (GO:0046641)2.54061737
133negative regulation of interleukin-12 production (GO:0032695)2.54039279
134regulation of interleukin-12 production (GO:0032655)2.53054815
135negative regulation of viral genome replication (GO:0045071)2.52928063
136regulation of nucleobase-containing compound transport (GO:0032239)2.52809582
137positive regulation of response to biotic stimulus (GO:0002833)2.52540629
138detection of bacterium (GO:0016045)2.52430725
139response to interleukin-15 (GO:0070672)2.52114298
140positive regulation of interleukin-17 production (GO:0032740)2.52038577
141cytokine secretion (GO:0050663)2.51223574
142histone H2A acetylation (GO:0043968)2.50615051
143negative regulation of bone remodeling (GO:0046851)2.48767910
144regulation of regulatory T cell differentiation (GO:0045589)2.47345026
145tolerance induction (GO:0002507)2.46642079
146regulation of vitamin D biosynthetic process (GO:0060556)2.46430473
147cytoplasmic mRNA processing body assembly (GO:0033962)2.46337942
148regulation of response to interferon-gamma (GO:0060330)2.45813307
149histone H3-K36 demethylation (GO:0070544)2.45622465
150lymphocyte homeostasis (GO:0002260)2.43955405
151negative regulation of mRNA processing (GO:0050686)2.43101237
152nuclear pore organization (GO:0006999)2.42592074
153T cell lineage commitment (GO:0002360)2.41567336
154attachment of spindle microtubules to kinetochore (GO:0008608)2.41058302
155histone H2A ubiquitination (GO:0033522)2.39584687
156positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.38277534
157neural tube formation (GO:0001841)2.35241226
158regulation of translation in response to stress (GO:0043555)2.34856640
159histone lysine methylation (GO:0034968)2.32402484
160mRNA splice site selection (GO:0006376)2.32019719
161regulation of histone methylation (GO:0031060)2.31428381
162negative regulation of osteoblast proliferation (GO:0033689)2.30977552
163positive regulation of protein oligomerization (GO:0032461)2.30938676
164histone lysine demethylation (GO:0070076)2.30539618
165negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.28826635
166negative regulation of DNA repair (GO:0045738)2.28187498
167negative regulation of mRNA metabolic process (GO:1903312)2.26883354
168alpha-beta T cell differentiation involved in immune response (GO:0002293)2.25875892
169alpha-beta T cell activation involved in immune response (GO:0002287)2.25875892
170T cell differentiation involved in immune response (GO:0002292)2.25875892

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.17850498
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse5.43759650
3IRF8_21731497_ChIP-ChIP_J774_Mouse4.50107144
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.39130027
5BP1_19119308_ChIP-ChIP_Hs578T_Human4.37858608
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse4.10865732
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human4.10401086
8IRF8_27001747_Chip-Seq_BMDM_Mouse3.34671740
9SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.28948043
10STAT3_20064451_ChIP-Seq_CD4+T_Mouse3.23553167
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.14930075
12* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.80831979
13RBPJ_22232070_ChIP-Seq_NCS_Mouse2.70854450
14SCL_19346495_ChIP-Seq_HPC-7_Human2.60761189
15Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.58070300
16RUNX_20019798_ChIP-Seq_JUKART_Human2.56432402
17EGR1_19374776_ChIP-ChIP_THP-1_Human2.55774079
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.54333500
19PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.32954223
20SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.31745037
21STAT4_19710469_ChIP-ChIP_TH1__Mouse2.31009078
22FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.28308779
23SMAD_19615063_ChIP-ChIP_OVARY_Human2.19464324
24E2F7_22180533_ChIP-Seq_HELA_Human2.17783353
25KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.17352899
26SALL1_21062744_ChIP-ChIP_HESCs_Human2.15173191
27RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.13796498
28* MYB_26560356_Chip-Seq_TH2_Human2.07513397
29GATA1_22025678_ChIP-Seq_K562_Human2.05823180
30* MYB_26560356_Chip-Seq_TH1_Human1.85182341
31* SPI1_23547873_ChIP-Seq_NB4_Human1.81609958
32CIITA_25753668_ChIP-Seq_RAJI_Human1.78741544
33STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.76899259
34GATA2_21666600_ChIP-Seq_HMVEC_Human1.75915533
35NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.72349845
36PU_27001747_Chip-Seq_BMDM_Mouse1.69649446
37VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.69401559
38E2F4_17652178_ChIP-ChIP_JURKAT_Human1.64966891
39BRD4_27068464_Chip-Seq_AML-cells_Mouse1.64023240
40ELK1_19687146_ChIP-ChIP_HELA_Human1.62251143
41PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.61410524
42WT1_19549856_ChIP-ChIP_CCG9911_Human1.60979608
43FOXM1_23109430_ChIP-Seq_U2OS_Human1.58996289
44* PADI4_21655091_ChIP-ChIP_MCF-7_Human1.58032304
45VDR_24787735_ChIP-Seq_THP-1_Human1.57405584
46MYC_22102868_ChIP-Seq_BL_Human1.55468281
47VDR_24763502_ChIP-Seq_THP-1_Human1.53095215
48PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.51758425
49* MAF_26560356_Chip-Seq_TH1_Human1.49005619
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.48706460
51RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.47955097
52EWS_26573619_Chip-Seq_HEK293_Human1.47319785
53SPI1_23127762_ChIP-Seq_K562_Human1.44613093
54VDR_23849224_ChIP-Seq_CD4+_Human1.44380299
55* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.43543273
56STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.42431694
57TP63_17297297_ChIP-ChIP_HaCaT_Human1.37356039
58ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.37228899
59* RUNX1_22412390_ChIP-Seq_EML_Mouse1.34257030
60BRD4_25478319_ChIP-Seq_HGPS_Human1.31617350
61CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.31010651
62* GATA3_27048872_Chip-Seq_THYMUS_Human1.29937345
63RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.29675950
64MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.27775741
65* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.26015110
66FUS_26573619_Chip-Seq_HEK293_Human1.25932922
67CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.25558070
68HOXB4_20404135_ChIP-ChIP_EML_Mouse1.24522498
69FOXP3_21729870_ChIP-Seq_TREG_Human1.20633743
70BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.20161811
71* GATA3_26560356_Chip-Seq_TH2_Human1.19920510
72* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.19473394
73SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.18865002
74PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18735342
75NOTCH1_21737748_ChIP-Seq_TLL_Human1.14037393
76* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13461681
77E2F1_21310950_ChIP-Seq_MCF-7_Human1.11181787
78UTX_26944678_Chip-Seq_JUKART_Human1.10635103
79FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.09949203
80E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.08927283
81CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.08680178
82GATA2_22383799_ChIP-Seq_G1ME_Mouse1.08525186
83GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06176069
84VDR_21846776_ChIP-Seq_THP-1_Human1.05493039
85TFEB_21752829_ChIP-Seq_HELA_Human1.02536164
86FLI1_27457419_Chip-Seq_LIVER_Mouse1.01939354
87OCT4_21477851_ChIP-Seq_ESCs_Mouse1.01494671
88EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.01269272
89MYCN_18555785_ChIP-Seq_MESCs_Mouse1.01023175
90NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.00875333
91ZFP57_27257070_Chip-Seq_ESCs_Mouse1.00354034
92PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00263038
93CDX2_19796622_ChIP-Seq_MESCs_Mouse0.99916048
94* FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.99403424
95OCT4_18555785_Chip-Seq_ESCs_Mouse0.98841129
96TCF7_22412390_ChIP-Seq_EML_Mouse0.98021172
97CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97839998
98P300_18555785_Chip-Seq_ESCs_Mouse0.97675859
99PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97092466
100SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.97022259
101CRX_20693478_ChIP-Seq_RETINA_Mouse0.96823139
102ESR1_21235772_ChIP-Seq_MCF-7_Human0.96811160
103EZH2_27294783_Chip-Seq_NPCs_Mouse0.95668979
104FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.95046554
105* SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.94202958
106* SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.94202958
107CMYC_18555785_Chip-Seq_ESCs_Mouse0.93948688
108NMYC_18555785_Chip-Seq_ESCs_Mouse0.93896043
109ELF1_17652178_ChIP-ChIP_JURKAT_Human0.93831895
110SALL4_18804426_ChIP-ChIP_XEN_Mouse0.93515657
111KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.92659250
112NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92445792
113E2F1_18555785_Chip-Seq_ESCs_Mouse0.91800676
114* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.91793573
115* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90879068
116CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90129546
117CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.89873401
118NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.89870100
119TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.89790631
120ERG_20887958_ChIP-Seq_HPC-7_Mouse0.89666784
121FOXO3_23340844_ChIP-Seq_DLD1_Human0.89327880
122GATA4_21415370_ChIP-Seq_HL-1_Mouse0.89104051
123EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88446484
124TP63_19390658_ChIP-ChIP_HaCaT_Human0.88446194
125SUZ12_27294783_Chip-Seq_NPCs_Mouse0.86741237
126NFE2_27457419_Chip-Seq_LIVER_Mouse0.85582224
127SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.82353715
128GATA2_19941826_ChIP-Seq_K562_Human0.81373994
129ZNF217_24962896_ChIP-Seq_MCF-7_Human0.80293871
130* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.80292522
131GATA1_19941827_ChIP-Seq_MEL_Mouse0.79987914
132CJUN_26792858_Chip-Seq_BT549_Human0.79946634
133GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79898714
134POU3F2_20337985_ChIP-ChIP_501MEL_Human0.78984425
135GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.76889846
136TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.76489206
137CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.76268414
138SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74950259
139GATA1_19941826_ChIP-Seq_K562_Human0.74602007
140SUZ12_18555785_Chip-Seq_ESCs_Mouse0.73500769
141STAT3_18555785_Chip-Seq_ESCs_Mouse0.73261746
142SOX2_20726797_ChIP-Seq_SW620_Human0.72585800
143TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.72527802
144P53_22387025_ChIP-Seq_ESCs_Mouse0.71940917
145NANOG_18555785_Chip-Seq_ESCs_Mouse0.71783902
146PU1_27457419_Chip-Seq_LIVER_Mouse0.71331224

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.23867011
2MP0000569_abnormal_digit_pigmentation4.10086599
3MP0009785_altered_susceptibility_to3.04951039
4MP0000685_abnormal_immune_system3.03130722
5MP0005671_abnormal_response_to3.01469721
6MP0005387_immune_system_phenotype2.92293702
7MP0001790_abnormal_immune_system2.92293702
8MP0002166_altered_tumor_susceptibility2.70899842
9MP0001800_abnormal_humoral_immune2.70832962
10MP0005000_abnormal_immune_tolerance2.68894676
11MP0002148_abnormal_hypersensitivity_rea2.64617990
12MP0002419_abnormal_innate_immunity2.63868679
13MP0003436_decreased_susceptibility_to2.62079957
14MP0002452_abnormal_antigen_presenting2.57309514
15MP0005025_abnormal_response_to2.54017610
16MP0003656_abnormal_erythrocyte_physiolo2.43601861
17MP0002723_abnormal_immune_serum2.42229093
18MP0002006_tumorigenesis2.41668843
19MP0003724_increased_susceptibility_to2.34045473
20MP0001819_abnormal_immune_cell2.28533356
21MP0002420_abnormal_adaptive_immunity2.26363584
22MP0005464_abnormal_platelet_physiology2.17708736
23MP0002396_abnormal_hematopoietic_system2.13262008
24MP0003183_abnormal_peptide_metabolism2.06331914
25MP0003300_gastrointestinal_ulcer2.03346709
26MP0003763_abnormal_thymus_physiology2.00220587
27MP0005174_abnormal_tail_pigmentation1.99104223
28MP0004947_skin_inflammation1.91329701
29MP0010094_abnormal_chromosome_stability1.84555857
30MP0010155_abnormal_intestine_physiology1.83798951
31MP0002398_abnormal_bone_marrow1.81048658
32MP0006082_CNS_inflammation1.80833958
33MP0001853_heart_inflammation1.80744019
34MP0000372_irregular_coat_pigmentation1.76760132
35MP0003195_calcinosis1.74430326
36MP0003950_abnormal_plasma_membrane1.73632320
37MP0000716_abnormal_immune_system1.73138273
38MP0001873_stomach_inflammation1.69486570
39MP0002405_respiratory_system_inflammati1.68278057
40MP0003303_peritoneal_inflammation1.68273330
41MP0008877_abnormal_DNA_methylation1.62643009
42MP0001845_abnormal_inflammatory_respons1.61865515
43MP0003172_abnormal_lysosome_physiology1.61703225
44MP0004808_abnormal_hematopoietic_stem1.58326069
45MP0004510_myositis1.56772362
46MP0001533_abnormal_skeleton_physiology1.53779850
47MP0002009_preneoplasia1.53048111
48MP0009278_abnormal_bone_marrow1.52954998
49MP0010307_abnormal_tumor_latency1.52497918
50MP0005397_hematopoietic_system_phenotyp1.51415367
51MP0001545_abnormal_hematopoietic_system1.51415367
52MP0002163_abnormal_gland_morphology1.48972289
53MP0005310_abnormal_salivary_gland1.44579310
54MP0009764_decreased_sensitivity_to1.40081808
55MP0002429_abnormal_blood_cell1.39285405
56MP0008007_abnormal_cellular_replicative1.39215624
57MP0000689_abnormal_spleen_morphology1.37491892
58MP0002722_abnormal_immune_system1.34929912
59MP0008961_abnormal_basal_metabolism1.33142450
60MP0000015_abnormal_ear_pigmentation1.31902760
61MP0002998_abnormal_bone_remodeling1.30526489
62MP0005058_abnormal_lysosome_morphology1.26319783
63MP0003111_abnormal_nucleus_morphology1.24778033
64MP0003077_abnormal_cell_cycle1.22987670
65MP0002933_joint_inflammation1.21739793
66MP0008469_abnormal_protein_level1.20855864
67MP0002877_abnormal_melanocyte_morpholog1.20314032
68MP0008057_abnormal_DNA_replication1.20225020
69MP0003448_altered_tumor_morphology1.19620331
70MP0003252_abnormal_bile_duct1.19200861
71MP0000371_diluted_coat_color1.19165654
72MP0003786_premature_aging1.17969048
73MP0000703_abnormal_thymus_morphology1.13146981
74MP0002138_abnormal_hepatobiliary_system1.12488684
75MP0000383_abnormal_hair_follicle1.12120028
76MP0003866_abnormal_defecation1.11294807
77MP0003045_fibrosis1.06994161
78MP0000465_gastrointestinal_hemorrhage1.06511754
79MP0002019_abnormal_tumor_incidence1.06079896
80MP0008058_abnormal_DNA_repair1.05770394
81MP0000858_altered_metastatic_potential1.04927379
82MP0001879_abnormal_lymphatic_vessel1.03665627
83MP0009333_abnormal_splenocyte_physiolog1.03498001
84MP0005379_endocrine/exocrine_gland_phen1.01994216
85MP0002928_abnormal_bile_duct1.01449501
86MP0005621_abnormal_cell_physiology1.00942295
87MP0003221_abnormal_cardiomyocyte_apopto0.99986367
88MP0005075_abnormal_melanosome_morpholog0.94775315
89MP0006054_spinal_hemorrhage0.93510099
90MP0000350_abnormal_cell_proliferation0.93131331
91MP0002095_abnormal_skin_pigmentation0.92263351
92MP0000490_abnormal_crypts_of0.90032026
93MP0005451_abnormal_body_composition0.88572166
94MP0005220_abnormal_exocrine_pancreas0.86751588
95MP0008438_abnormal_cutaneous_collagen0.86380062
96MP0000767_abnormal_smooth_muscle0.85711416
97MP0002254_reproductive_system_inflammat0.84789430
98MP0000013_abnormal_adipose_tissue0.83712561
99MP0010352_gastrointestinal_tract_polyps0.82888082
100MP0003566_abnormal_cell_adhesion0.81977376
101MP0003091_abnormal_cell_migration0.81737219
102MP0009763_increased_sensitivity_to0.81693546
103MP0004381_abnormal_hair_follicle0.80659430
104MP0008995_early_reproductive_senescence0.80415158
105MP0001851_eye_inflammation0.79940992
106MP0005390_skeleton_phenotype0.79457283
107MP0002168_other_aberrant_phenotype0.79265678
108MP0002693_abnormal_pancreas_physiology0.77542588
109MP0005384_cellular_phenotype0.77254772
110MP0008260_abnormal_autophagy0.76218993
111MP0005645_abnormal_hypothalamus_physiol0.75470677
112MP0004782_abnormal_surfactant_physiolog0.74276793
113MP0003795_abnormal_bone_structure0.73814016
114MP0001191_abnormal_skin_condition0.73712752
115MP0004134_abnormal_chest_morphology0.72345834
116MP0010678_abnormal_skin_adnexa0.71214139
117MP0003828_pulmonary_edema0.70185683
118MP0000003_abnormal_adipose_tissue0.69795032
119MP0001348_abnormal_lacrimal_gland0.66588889
120MP0000343_altered_response_to0.65095834
121MP0000598_abnormal_liver_morphology0.65011914
122MP0005408_hypopigmentation0.64802239
123MP0003279_aneurysm0.64629981
124MP0009765_abnormal_xenobiotic_induced0.64160674
125MP0005076_abnormal_cell_differentiation0.63654975
126MP0002132_abnormal_respiratory_system0.63483977
127MP0003191_abnormal_cellular_cholesterol0.63426004
128MP0000313_abnormal_cell_death0.63396872
129MP0001958_emphysema0.63192808
130MP0002277_abnormal_respiratory_mucosa0.63014590
131MP0000249_abnormal_blood_vessel0.62189557
132MP0002075_abnormal_coat/hair_pigmentati0.60525642
133MP0002136_abnormal_kidney_physiology0.59713447
134MP0003943_abnormal_hepatobiliary_system0.58674510
135MP0001186_pigmentation_phenotype0.58571477
136MP0003453_abnormal_keratinocyte_physiol0.58410002
137MP0001915_intracranial_hemorrhage0.57151057

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)4.96418733
2Recurrent bacterial skin infections (HP:0005406)4.78133499
3Eczematoid dermatitis (HP:0000976)4.51535132
4Myositis (HP:0100614)3.96611299
5Recurrent fungal infections (HP:0002841)3.90248570
6Retrobulbar optic neuritis (HP:0100654)3.87418874
7Optic neuritis (HP:0100653)3.87418874
8Recurrent viral infections (HP:0004429)3.74435817
9Orchitis (HP:0100796)3.53138997
10Chronic otitis media (HP:0000389)3.40667316
11Recurrent skin infections (HP:0001581)3.35154142
12Mediastinal lymphadenopathy (HP:0100721)3.32428832
13Periodontitis (HP:0000704)3.29704693
14Abnormality of the fingertips (HP:0001211)3.28609363
15Recurrent cutaneous fungal infections (HP:0011370)3.26730823
16Chronic mucocutaneous candidiasis (HP:0002728)3.26730823
17Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.22795139
18Vasculitis (HP:0002633)3.22151678
19Autoimmune thrombocytopenia (HP:0001973)3.21595962
20Elevated erythrocyte sedimentation rate (HP:0003565)3.09718387
21Recurrent gram-negative bacterial infections (HP:0005420)3.08947486
22Abnormal delayed hypersensitivity skin test (HP:0002963)3.07592984
23Pulmonary infiltrates (HP:0002113)3.02678471
24Meningitis (HP:0001287)2.93646157
25Combined immunodeficiency (HP:0005387)2.91970686
26Agammaglobulinemia (HP:0004432)2.91064128
27Eosinophilia (HP:0001880)2.90919669
28Gingivitis (HP:0000230)2.87066606
29Abnormality of macrophages (HP:0004311)2.86162814
30Volvulus (HP:0002580)2.82890200
31Fatigue (HP:0012378)2.81882441
32Chronic diarrhea (HP:0002028)2.81531937
33Cutaneous melanoma (HP:0012056)2.79646877
34Abnormality of T cell number (HP:0011839)2.74362673
35Pustule (HP:0200039)2.66106505
36Panhypogammaglobulinemia (HP:0003139)2.64956592
37T lymphocytopenia (HP:0005403)2.64733323
38Hemoptysis (HP:0002105)2.64245557
39Arterial thrombosis (HP:0004420)2.63959071
40Hematochezia (HP:0002573)2.62840198
41Stomatitis (HP:0010280)2.59447879
42Leukocytosis (HP:0001974)2.57421560
43Prostate neoplasm (HP:0100787)2.56367946
44Papillary thyroid carcinoma (HP:0002895)2.55827732
45Thyroiditis (HP:0100646)2.55809167
46Recurrent bronchitis (HP:0002837)2.54371278
47Granulocytopenia (HP:0001913)2.53647992
48Thick nail (HP:0001805)2.50162774
49Cellulitis (HP:0100658)2.49651626
50B lymphocytopenia (HP:0010976)2.48692602
51Abnormality of B cell number (HP:0010975)2.48692602
52Colitis (HP:0002583)2.47988384
53Keratoconjunctivitis sicca (HP:0001097)2.46064453
54Osteomyelitis (HP:0002754)2.46064171
55Deep philtrum (HP:0002002)2.45609475
56Abnormality of eosinophils (HP:0001879)2.44534773
57Recurrent pneumonia (HP:0006532)2.38509689
58Gingival bleeding (HP:0000225)2.36477288
59Overlapping toe (HP:0001845)2.36123349
60Inflammation of the large intestine (HP:0002037)2.34839326
61Acute hepatic failure (HP:0006554)2.33668936
62Thyroid carcinoma (HP:0002890)2.33333315
63Submucous cleft hard palate (HP:0000176)2.31620366
64Heterotopia (HP:0002282)2.30850895
65Lymphopenia (HP:0001888)2.30850624
66Prolonged bleeding time (HP:0003010)2.28963199
67Keratoconjunctivitis (HP:0001096)2.28759904
68Abnormality of T cells (HP:0002843)2.28143634
69IgA deficiency (HP:0002720)2.25952269
70Chronic obstructive pulmonary disease (HP:0006510)2.25924153
71Obstructive lung disease (HP:0006536)2.25924153
72Vacuolated lymphocytes (HP:0001922)2.24865228
73Basal cell carcinoma (HP:0002671)2.22289169
74Abnormality of cells of the lymphoid lineage (HP:0012140)2.21377869
75Spontaneous hematomas (HP:0007420)2.17338887
76Thickened calvaria (HP:0002684)2.17322531
77Basal ganglia calcification (HP:0002135)2.17186707
78Acute myeloid leukemia (HP:0004808)2.16256449
79Increased IgM level (HP:0003496)2.15129514
80Myelodysplasia (HP:0002863)2.13431004
81Acute lymphatic leukemia (HP:0006721)2.12614588
82Premature loss of primary teeth (HP:0006323)2.12080353
83Increased IgE level (HP:0003212)2.11939477
84Abnormality of T cell physiology (HP:0011840)2.11815002
85Gastrointestinal inflammation (HP:0004386)2.11626084
86Cheilitis (HP:0100825)2.11119766
87Gastrointestinal stroma tumor (HP:0100723)2.10539054
88Autoimmune hemolytic anemia (HP:0001890)2.09822057
89Increased neuronal autofluorescent lipopigment (HP:0002074)2.09761957
90Spondylolisthesis (HP:0003302)2.09132101
91Epistaxis (HP:0000421)2.08335850
92Viral hepatitis (HP:0006562)2.07263680
93Encephalitis (HP:0002383)2.06800905
94Absent frontal sinuses (HP:0002688)2.06533692
95Stomach cancer (HP:0012126)2.06082332
96IgM deficiency (HP:0002850)2.04056810
97Recurrent lower respiratory tract infections (HP:0002783)2.02566651
98Pancreatic islet-cell hyperplasia (HP:0004510)2.02043836
99Abnormality of the prostate (HP:0008775)2.01336690
100Hypoplasia of the thymus (HP:0000778)2.01317349
101Abnormality of the common coagulation pathway (HP:0010990)2.01253948
102Cystic hygroma (HP:0000476)2.01122147
103Abnormality of endocrine pancreas physiology (HP:0012093)2.00845622
104Abnormality of the pancreatic islet cells (HP:0006476)2.00845622
105Thrombocytosis (HP:0001894)2.00535177
106IgG deficiency (HP:0004315)1.98996274
107Hypergammaglobulinemia (HP:0010702)1.96023161
108Curly hair (HP:0002212)1.95648019
109Interstitial pulmonary disease (HP:0006530)1.95480557
110Keratitis (HP:0000491)1.95352927
111Abnormality of the peritoneum (HP:0002585)1.93014252
112Severe combined immunodeficiency (HP:0004430)1.92793071
113Degeneration of anterior horn cells (HP:0002398)1.92631180
114Abnormality of the anterior horn cell (HP:0006802)1.92631180
115Nephroblastoma (Wilms tumor) (HP:0002667)1.92497193
116Albinism (HP:0001022)1.91739600
117Emphysema (HP:0002097)1.89982043
118Spinal cord lesions (HP:0100561)1.89486462
119Syringomyelia (HP:0003396)1.89486462
120Somatic mutation (HP:0001428)1.89139993
121Papilloma (HP:0012740)1.88263509
122Verrucae (HP:0200043)1.88263509
123Chronic sinusitis (HP:0011109)1.88038010
124Increased cerebral lipofuscin (HP:0011813)1.86359806
125Lymphoma (HP:0002665)1.86170469
126Neoplasm of the tracheobronchial system (HP:0100552)1.86146789
127Chest pain (HP:0100749)1.85291302
128Large for gestational age (HP:0001520)1.85237042
129Skin ulcer (HP:0200042)1.83070821
130Prominent metopic ridge (HP:0005487)1.82676843
131Embryonal renal neoplasm (HP:0011794)1.81822653
132Transitional cell carcinoma of the bladder (HP:0006740)1.80207906
133Lip pit (HP:0100267)1.80071278
134Broad alveolar ridges (HP:0000187)1.79956462
135Sepsis (HP:0100806)1.79121744
136Prominent nose (HP:0000448)1.78299988
137Alveolar cell carcinoma (HP:0006519)1.77153985
138Gastrointestinal infarctions (HP:0005244)1.77021235
139Abnormality of the frontal sinuses (HP:0002687)1.76886754
140Low anterior hairline (HP:0000294)1.76823985
141Recurrent sinusitis (HP:0011108)1.76603435
142Asymmetry of the thorax (HP:0001555)1.75996540
143Microvesicular hepatic steatosis (HP:0001414)1.75099628
144White forelock (HP:0002211)1.74459470
145Chromsome breakage (HP:0040012)1.74127149
146Joint swelling (HP:0001386)1.72560328
147Ascites (HP:0001541)1.72157450
148Bladder neoplasm (HP:0009725)1.70144136
149Bladder carcinoma (HP:0002862)1.70144136
150Abnormality of the metopic suture (HP:0005556)1.69008191
151Aortic aneurysm (HP:0004942)1.67454053
152Truncal obesity (HP:0001956)1.66651164
153Broad palm (HP:0001169)1.64371958
154Ureteral obstruction (HP:0006000)1.63522081

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK34.28280179
2MAP3K143.94278707
3IRAK33.32391575
4AKT32.98930780
5IRAK42.96454691
6JAK32.95747174
7TXK2.87180296
8MAP4K12.81306712
9TYK22.75989822
10IKBKE2.67434037
11KIT2.48506944
12JAK12.43277890
13TBK12.40204351
14BRSK22.37133291
15MAP3K132.26296113
16TAOK32.18612291
17BCKDK2.10330652
18RIPK42.09125700
19PASK2.00058477
20IKBKB1.99765220
21TEC1.86594629
22BLK1.84259145
23CHUK1.63909579
24EIF2AK11.62359713
25INSRR1.62017825
26TGFBR21.60674919
27FGFR41.55853465
28CAMKK21.53682301
29MKNK11.48435573
30BTK1.47497303
31SIK31.43724617
32ZAP701.42761475
33MKNK21.39805056
34FGFR31.34298711
35SIK21.34055444
36ITK1.33884996
37SYK1.32788824
38PAK31.31399565
39MELK1.30357525
40LCK1.28744469
41TRIM281.26609598
42CSF1R1.26271929
43ERN11.24714594
44PRPF4B1.24084911
45EPHB11.23966741
46NLK1.21842208
47NUAK11.21461642
48MARK31.21312444
49EPHA31.21052293
50IRAK11.20391686
51BCR1.18028934
52CSK1.14674480
53HCK1.14199835
54BRD41.12617871
55SIK11.06574356
56TRPM71.02324694
57LYN1.01591641
58CAMK1D0.99517374
59PKN20.98092769
60FLT30.97623112
61STK100.96699536
62YES10.96230863
63EIF2AK20.94651181
64PTK60.89809176
65FRK0.87267251
66NEK90.86939416
67CDK120.86879075
68JAK20.86495499
69PIM10.84931622
70CAMK1G0.84665431
71WNK10.83589794
72MST40.81812161
73HIPK20.77326885
74RIPK10.77184392
75FES0.75548574
76PIK3CG0.75270095
77NEK10.70256932
78RPS6KA40.69833490
79PRKCQ0.69753634
80PIK3CA0.69505394
81STK240.68770290
82ZAK0.67867486
83BUB10.65612872
84FGR0.64939332
85PRKAA20.64339766
86ATM0.63442544
87TIE10.61523389
88CHEK10.60958040
89STK30.60663018
90TNIK0.60378795
91IRAK20.59861700
92CLK10.59680996
93MAP3K50.59477587
94MAP2K30.58330337
95CDK60.57798276
96PDGFRB0.57529802
97ABL10.56211911
98MAP3K100.56200112
99BMPR20.55633735
100TTN0.54726232
101CDK40.54255560
102ERBB30.53773003
103STK40.53093694
104MAPK150.52827966
105MAP3K40.48851878
106IGF1R0.48262384
107MAPK70.47511051
108LATS10.47313615
109CDK80.47072305
110FGFR20.45867570
111RPS6KB20.45189307
112MAP3K70.44047515
113MUSK0.41357776
114RAF10.41184493
115CDK90.41111917
116ATR0.40927903
117RET0.40751919
118MATK0.39406017
119SGK20.38203334
120PRKCH0.38076010
121PLK30.37404128
122FGFR10.37356678
123BRSK10.36968845
124PDGFRA0.36166456
125CDC42BPA0.35981105
126SGK30.34862463
127GRK10.34672303
128BMPR1B0.29531201
129SGK10.29459678
130MAPK30.28839769
131MAPKAPK20.28817958
132EGFR0.27873501
133PRKCD0.27815202
134MAPK110.27007577
135RPS6KA60.26455426
136KDR0.24985857

Predicted pathways (KEGG)

RankGene SetZ-score
1NF-kappa B signaling pathway_Homo sapiens_hsa040642.87803318
2Primary immunodeficiency_Homo sapiens_hsa053402.65241470
3Leishmaniasis_Homo sapiens_hsa051402.54601560
4Measles_Homo sapiens_hsa051622.50692590
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.38875894
6Toll-like receptor signaling pathway_Homo sapiens_hsa046202.29885092
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.28491522
8RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.24447634
9Osteoclast differentiation_Homo sapiens_hsa043802.17254633
10NOD-like receptor signaling pathway_Homo sapiens_hsa046212.15833390
11Graft-versus-host disease_Homo sapiens_hsa053322.11718087
12Allograft rejection_Homo sapiens_hsa053302.10684704
13Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.04852650
14Hematopoietic cell lineage_Homo sapiens_hsa046402.01883752
15B cell receptor signaling pathway_Homo sapiens_hsa046621.93579022
16TNF signaling pathway_Homo sapiens_hsa046681.82588305
17Influenza A_Homo sapiens_hsa051641.79719139
18Caffeine metabolism_Homo sapiens_hsa002321.76546476
19Herpes simplex infection_Homo sapiens_hsa051681.72442993
20Non-small cell lung cancer_Homo sapiens_hsa052231.70195226
21Jak-STAT signaling pathway_Homo sapiens_hsa046301.57956628
22Legionellosis_Homo sapiens_hsa051341.57586950
23Toxoplasmosis_Homo sapiens_hsa051451.57291423
24Malaria_Homo sapiens_hsa051441.56370018
25Antigen processing and presentation_Homo sapiens_hsa046121.56291405
26Staphylococcus aureus infection_Homo sapiens_hsa051501.54263326
27Circadian rhythm_Homo sapiens_hsa047101.47493332
28Tuberculosis_Homo sapiens_hsa051521.43383067
29mTOR signaling pathway_Homo sapiens_hsa041501.42860088
30Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.39711011
31Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.39399307
32Pertussis_Homo sapiens_hsa051331.36874176
33T cell receptor signaling pathway_Homo sapiens_hsa046601.36479149
34One carbon pool by folate_Homo sapiens_hsa006701.28382191
35Hepatitis B_Homo sapiens_hsa051611.24846116
36Autoimmune thyroid disease_Homo sapiens_hsa053201.24172796
37RNA degradation_Homo sapiens_hsa030181.22081207
38Chemokine signaling pathway_Homo sapiens_hsa040621.21041444
39Asthma_Homo sapiens_hsa053101.20819741
40Apoptosis_Homo sapiens_hsa042101.20609640
41Hepatitis C_Homo sapiens_hsa051601.19683140
42Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.19390689
43Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.18440534
44Rheumatoid arthritis_Homo sapiens_hsa053231.14954043
45Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.12367399
46Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12328639
47Acute myeloid leukemia_Homo sapiens_hsa052211.09783487
48Small cell lung cancer_Homo sapiens_hsa052221.09579886
49Type I diabetes mellitus_Homo sapiens_hsa049401.07350020
50Renal cell carcinoma_Homo sapiens_hsa052111.07225258
51African trypanosomiasis_Homo sapiens_hsa051431.07187038
52Other glycan degradation_Homo sapiens_hsa005111.06998607
53Colorectal cancer_Homo sapiens_hsa052101.05305278
54Cell cycle_Homo sapiens_hsa041101.04852099
55Endometrial cancer_Homo sapiens_hsa052131.04549181
56Leukocyte transendothelial migration_Homo sapiens_hsa046701.03308389
57AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.02900751
58Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.98430953
59Fanconi anemia pathway_Homo sapiens_hsa034600.95208704
60Viral myocarditis_Homo sapiens_hsa054160.94551590
61Spliceosome_Homo sapiens_hsa030400.93724491
62Thyroid cancer_Homo sapiens_hsa052160.93257787
63Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.92588105
64Chronic myeloid leukemia_Homo sapiens_hsa052200.92275675
65Lysosome_Homo sapiens_hsa041420.91234867
66Pancreatic cancer_Homo sapiens_hsa052120.87874863
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.85107000
68Basal transcription factors_Homo sapiens_hsa030220.85028094
69Platelet activation_Homo sapiens_hsa046110.84438138
70Dorso-ventral axis formation_Homo sapiens_hsa043200.83679413
71ABC transporters_Homo sapiens_hsa020100.83106477
72Non-homologous end-joining_Homo sapiens_hsa034500.82768978
73Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82251180
74Regulation of autophagy_Homo sapiens_hsa041400.82247765
75Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.80795106
76Prolactin signaling pathway_Homo sapiens_hsa049170.79393245
77Salmonella infection_Homo sapiens_hsa051320.78831570
78Shigellosis_Homo sapiens_hsa051310.78613202
79Propanoate metabolism_Homo sapiens_hsa006400.78143304
80Glycosaminoglycan degradation_Homo sapiens_hsa005310.75635384
81Phagosome_Homo sapiens_hsa041450.73328857
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.72836684
83Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.72791723
84Choline metabolism in cancer_Homo sapiens_hsa052310.68552307
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67359769
86Protein export_Homo sapiens_hsa030600.62903718
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61724734
88Insulin resistance_Homo sapiens_hsa049310.61490035
89HTLV-I infection_Homo sapiens_hsa051660.61016612
90Prostate cancer_Homo sapiens_hsa052150.60630516
91Nucleotide excision repair_Homo sapiens_hsa034200.59110672
92Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57504412
93Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57444211
94Amoebiasis_Homo sapiens_hsa051460.57358865
95Maturity onset diabetes of the young_Homo sapiens_hsa049500.56681965
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.56147549
97Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55609200
98Melanoma_Homo sapiens_hsa052180.55406474
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55269529
100Lysine degradation_Homo sapiens_hsa003100.55202436
101Glioma_Homo sapiens_hsa052140.54408755
102Notch signaling pathway_Homo sapiens_hsa043300.53603678
103ECM-receptor interaction_Homo sapiens_hsa045120.52835116
104Epstein-Barr virus infection_Homo sapiens_hsa051690.52033399
105Type II diabetes mellitus_Homo sapiens_hsa049300.51969063
106Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.50954139
107RNA transport_Homo sapiens_hsa030130.50666854
108Adipocytokine signaling pathway_Homo sapiens_hsa049200.50381529
109N-Glycan biosynthesis_Homo sapiens_hsa005100.48851901
110Viral carcinogenesis_Homo sapiens_hsa052030.48678438
111MicroRNAs in cancer_Homo sapiens_hsa052060.47475861
112Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47196787
113FoxO signaling pathway_Homo sapiens_hsa040680.47065955
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45415649
115Neurotrophin signaling pathway_Homo sapiens_hsa047220.44035249
116Sphingolipid signaling pathway_Homo sapiens_hsa040710.43596314
117p53 signaling pathway_Homo sapiens_hsa041150.43010275
118Sphingolipid metabolism_Homo sapiens_hsa006000.42835688
119Inositol phosphate metabolism_Homo sapiens_hsa005620.42825943
120Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42757024
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.42734183
122Focal adhesion_Homo sapiens_hsa045100.41210077
123Proteoglycans in cancer_Homo sapiens_hsa052050.41006244
124Adherens junction_Homo sapiens_hsa045200.36795023
125Regulation of actin cytoskeleton_Homo sapiens_hsa048100.36657492
126Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.33685992
127Vitamin digestion and absorption_Homo sapiens_hsa049770.32104854
128Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30690272

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