ZCCHC18

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)7.77659761
2nucleobase catabolic process (GO:0046113)6.20252403
3neuron cell-cell adhesion (GO:0007158)5.49049053
4vocalization behavior (GO:0071625)5.28108397
5regulation of short-term neuronal synaptic plasticity (GO:0048172)5.18923628
6synaptic vesicle exocytosis (GO:0016079)5.16825018
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.76079947
8regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.73071906
9protein localization to synapse (GO:0035418)4.53881836
10regulation of synaptic vesicle exocytosis (GO:2000300)4.52621742
11regulation of glutamate receptor signaling pathway (GO:1900449)4.49478100
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.40074151
13positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.32562605
14presynaptic membrane assembly (GO:0097105)4.32240528
15ionotropic glutamate receptor signaling pathway (GO:0035235)4.29644776
16establishment of mitochondrion localization (GO:0051654)4.27474130
17glutamate secretion (GO:0014047)4.25900445
18neurotransmitter secretion (GO:0007269)4.25592003
19sequestering of actin monomers (GO:0042989)4.21897767
20neuronal action potential propagation (GO:0019227)4.20549963
21gamma-aminobutyric acid signaling pathway (GO:0007214)4.19384649
22behavioral response to nicotine (GO:0035095)4.18313730
23glutamate receptor signaling pathway (GO:0007215)4.12065449
24neuron-neuron synaptic transmission (GO:0007270)4.05099717
25negative regulation of synaptic transmission, GABAergic (GO:0032229)4.03707280
26regulation of synaptic vesicle transport (GO:1902803)4.02906540
27negative regulation of microtubule polymerization (GO:0031115)4.00853523
28presynaptic membrane organization (GO:0097090)4.00231925
29neurotransmitter-gated ion channel clustering (GO:0072578)3.96171252
30synaptic transmission, glutamatergic (GO:0035249)3.88116051
31neuron recognition (GO:0008038)3.86101662
32locomotory exploration behavior (GO:0035641)3.84076253
33postsynaptic membrane organization (GO:0001941)3.83783840
34response to histamine (GO:0034776)3.81506794
35ATP hydrolysis coupled proton transport (GO:0015991)3.77191897
36energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.77191897
37dendritic spine morphogenesis (GO:0060997)3.75992052
38synaptic vesicle maturation (GO:0016188)3.74186457
39synaptic vesicle docking involved in exocytosis (GO:0016081)3.66497741
40neurotransmitter transport (GO:0006836)3.65318528
41cell migration in hindbrain (GO:0021535)3.64671125
42auditory behavior (GO:0031223)3.60633532
43regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.60505000
44exploration behavior (GO:0035640)3.59764083
45retinal ganglion cell axon guidance (GO:0031290)3.58196916
46startle response (GO:0001964)3.58189750
47positive regulation of synapse assembly (GO:0051965)3.56213692
48neurofilament cytoskeleton organization (GO:0060052)3.55277669
49long-term synaptic potentiation (GO:0060291)3.54524376
50gamma-aminobutyric acid transport (GO:0015812)3.52081802
51positive regulation of synaptic transmission, GABAergic (GO:0032230)3.51971296
52transferrin transport (GO:0033572)3.51191323
53transmission of nerve impulse (GO:0019226)3.47248249
54regulation of excitatory postsynaptic membrane potential (GO:0060079)3.45773506
55regulation of glutamate secretion (GO:0014048)3.45724376
56nonmotile primary cilium assembly (GO:0035058)3.45246542
57short-term memory (GO:0007614)3.44331627
58cerebral cortex radially oriented cell migration (GO:0021799)3.43504336
59mitochondrion transport along microtubule (GO:0047497)3.42693146
60establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.42693146
61regulation of synaptic transmission, glutamatergic (GO:0051966)3.41403623
62regulation of long-term neuronal synaptic plasticity (GO:0048169)3.40509096
63regulation of neuronal synaptic plasticity (GO:0048168)3.38377104
64regulation of postsynaptic membrane potential (GO:0060078)3.36162898
65proline transport (GO:0015824)3.35132308
66regulation of neurotransmitter levels (GO:0001505)3.34890122
67membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.32686531
68G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.32029324
69negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.29544607
70regulation of vesicle fusion (GO:0031338)3.29456449
71trivalent inorganic cation transport (GO:0072512)3.26997243
72ferric iron transport (GO:0015682)3.26997243
73female mating behavior (GO:0060180)3.25421522
74synaptic vesicle endocytosis (GO:0048488)3.23619259
75long-term memory (GO:0007616)3.23274159
76adaptation of signaling pathway (GO:0023058)3.22581786
77regulation of protein kinase A signaling (GO:0010738)3.21164278
78axonal fasciculation (GO:0007413)3.20737571
79positive regulation of synapse maturation (GO:0090129)3.19438436
80intraciliary transport (GO:0042073)3.17825525
81central nervous system projection neuron axonogenesis (GO:0021952)3.16917277
82glycosphingolipid biosynthetic process (GO:0006688)3.16593034
83cerebellar granule cell differentiation (GO:0021707)3.15982263
84behavioral fear response (GO:0001662)3.15691047
85behavioral defense response (GO:0002209)3.15691047
86detection of calcium ion (GO:0005513)3.14888659
87regulation of neurotransmitter secretion (GO:0046928)3.12966898
88calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.11797039
89positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.11364194
90positive regulation of membrane potential (GO:0045838)3.10950670
91fear response (GO:0042596)3.08065924
92synapse assembly (GO:0007416)3.07352335
93regulation of synaptic transmission, GABAergic (GO:0032228)3.06493049
94regulation of female receptivity (GO:0045924)3.03919180
95positive regulation of microtubule polymerization or depolymerization (GO:0031112)3.02233686
96mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.02127442
97adult walking behavior (GO:0007628)3.02115361
98regulation of synaptic plasticity (GO:0048167)3.00244306
99adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.99933864
100striatum development (GO:0021756)2.99689246
101synaptic transmission (GO:0007268)2.96817537
102head development (GO:0060322)2.96365265
103neuronal action potential (GO:0019228)2.95872076
104regulation of synapse structural plasticity (GO:0051823)2.95708822
105negative regulation of dendrite morphogenesis (GO:0050774)2.95461329
106regulation of neurotransmitter transport (GO:0051588)2.95251702
107neuromuscular process controlling posture (GO:0050884)2.93949121
108membrane depolarization (GO:0051899)2.93593482
109regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.93481988
110layer formation in cerebral cortex (GO:0021819)2.93147407
111positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.92868455
112membrane hyperpolarization (GO:0060081)2.92799183
113regulation of dopamine secretion (GO:0014059)2.92347226
114positive regulation of neurotransmitter transport (GO:0051590)2.91689528
115negative regulation of neurotransmitter transport (GO:0051589)2.90844593
116regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.89757158
117behavioral response to cocaine (GO:0048148)2.89282113
118activation of protein kinase A activity (GO:0034199)2.89274262
119positive regulation of synaptic transmission (GO:0050806)2.89114681
120regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.88745707
121establishment of synaptic vesicle localization (GO:0097480)2.88299210
122synaptic vesicle transport (GO:0048489)2.88299210
123cerebellar Purkinje cell differentiation (GO:0021702)2.87549066
124learning (GO:0007612)2.87058493
125protein localization to cilium (GO:0061512)2.86633520
126olfactory bulb development (GO:0021772)2.83831211
127regulation of synapse assembly (GO:0051963)2.83820954
128mechanosensory behavior (GO:0007638)2.83128240
129mating behavior (GO:0007617)2.81821236
130dendrite morphogenesis (GO:0048813)2.81691381
131synapse organization (GO:0050808)2.81429508
132positive regulation of dendritic spine morphogenesis (GO:0061003)2.77045740
133regulation of microtubule polymerization (GO:0031113)2.76224003
134regulation of feeding behavior (GO:0060259)2.74708240
135heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.73950009
136central nervous system neuron axonogenesis (GO:0021955)2.72289231
137neuron fate determination (GO:0048664)2.69182238
138alkaloid metabolic process (GO:0009820)2.65084920
139synaptic transmission, cholinergic (GO:0007271)2.63425537
140neuronal ion channel clustering (GO:0045161)2.63054108
141membrane depolarization during action potential (GO:0086010)2.60658513
142response to auditory stimulus (GO:0010996)2.60021869
143hippocampus development (GO:0021766)2.57551869
144epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.56606594
145cytoskeleton-dependent intracellular transport (GO:0030705)2.56377787
146cerebral cortex cell migration (GO:0021795)2.53280265
147epithelial cilium movement (GO:0003351)2.52785696
148positive regulation of amino acid transport (GO:0051957)2.50727524
149neuron migration (GO:0001764)2.50050778
150protein complex biogenesis (GO:0070271)2.49765986
151nervous system development (GO:0007399)2.47850561
152positive regulation of mitochondrial fission (GO:0090141)2.46440710
153dopamine biosynthetic process (GO:0042416)2.45734754
154ubiquinone metabolic process (GO:0006743)2.45158093
155cilium morphogenesis (GO:0060271)2.44844051
156limb bud formation (GO:0060174)2.44030538
157cilium assembly (GO:0042384)2.43784670

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.76632577
2GBX2_23144817_ChIP-Seq_PC3_Human4.17963547
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.07057348
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.92525385
5TAF15_26573619_Chip-Seq_HEK293_Human2.91603742
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.89638452
7REST_21632747_ChIP-Seq_MESCs_Mouse2.63489391
8SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.58275547
9EZH2_27304074_Chip-Seq_ESCs_Mouse2.49722239
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.45074908
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.44570569
12SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.42395101
13CTBP2_25329375_ChIP-Seq_LNCAP_Human2.38349812
14RNF2_18974828_ChIP-Seq_MESCs_Mouse2.38158850
15EZH2_18974828_ChIP-Seq_MESCs_Mouse2.38158850
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.35950231
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.30630669
18SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.29244807
19MTF2_20144788_ChIP-Seq_MESCs_Mouse2.26687764
20ZFP57_27257070_Chip-Seq_ESCs_Mouse2.23906073
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.23057469
22CTBP1_25329375_ChIP-Seq_LNCAP_Human2.21620056
23RBPJ_22232070_ChIP-Seq_NCS_Mouse2.17861156
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.15823308
25TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.11759496
26E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.05085210
27CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.03137381
28BMI1_23680149_ChIP-Seq_NPCS_Mouse2.02546744
29SUZ12_27294783_Chip-Seq_ESCs_Mouse2.01652567
30EZH2_27294783_Chip-Seq_ESCs_Mouse1.99962652
31IKZF1_21737484_ChIP-ChIP_HCT116_Human1.98021042
32RARB_27405468_Chip-Seq_BRAIN_Mouse1.93067233
33RNF2_27304074_Chip-Seq_ESCs_Mouse1.89770195
34SMAD4_21799915_ChIP-Seq_A2780_Human1.88672639
35P300_19829295_ChIP-Seq_ESCs_Human1.87808924
36HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.87743190
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.81004462
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.76976047
39DROSHA_22980978_ChIP-Seq_HELA_Human1.76588703
40AR_21572438_ChIP-Seq_LNCaP_Human1.71305948
41CBX2_27304074_Chip-Seq_ESCs_Mouse1.69585349
42IGF1R_20145208_ChIP-Seq_DFB_Human1.66470892
43ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.64898127
44HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.64346038
45FUS_26573619_Chip-Seq_HEK293_Human1.64192473
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.63687001
47VDR_22108803_ChIP-Seq_LS180_Human1.61873028
48SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59540679
49RNF2_27304074_Chip-Seq_NSC_Mouse1.56650654
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.55788226
51PIAS1_25552417_ChIP-Seq_VCAP_Human1.51622010
52ZNF274_21170338_ChIP-Seq_K562_Hela1.50918382
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.49189686
54OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45455366
55PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.42088200
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41984779
57SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41667756
58AR_25329375_ChIP-Seq_VCAP_Human1.41238696
59NR3C1_23031785_ChIP-Seq_PC12_Mouse1.36615195
60TP53_22573176_ChIP-Seq_HFKS_Human1.35393564
61ER_23166858_ChIP-Seq_MCF-7_Human1.34018898
62SOX2_21211035_ChIP-Seq_LN229_Gbm1.33193089
63UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.29797632
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.29698221
65NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.28483648
66STAT3_23295773_ChIP-Seq_U87_Human1.24920522
67TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.24342472
68IRF1_19129219_ChIP-ChIP_H3396_Human1.22996276
69TAL1_26923725_Chip-Seq_HPCs_Mouse1.18284380
70RUNX2_22187159_ChIP-Seq_PCA_Human1.17202928
71CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16512559
72TCF4_23295773_ChIP-Seq_U87_Human1.16343089
73MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.15681457
74JUN_21703547_ChIP-Seq_K562_Human1.14996026
75POU5F1_16153702_ChIP-ChIP_HESCs_Human1.14985817
76SMAD_19615063_ChIP-ChIP_OVARY_Human1.13791096
77AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12737203
78ERG_21242973_ChIP-ChIP_JURKAT_Human1.11681190
79MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.11209647
80MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09966261
81KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09525513
82NANOG_18555785_Chip-Seq_ESCs_Mouse1.09448744
83ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.09052427
84P53_22127205_ChIP-Seq_FIBROBLAST_Human1.07938284
85RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.07632388
86PRDM14_20953172_ChIP-Seq_ESCs_Human1.07343226
87FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06451246
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05152467
89KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03667719
90RING1B_27294783_Chip-Seq_ESCs_Mouse1.03613270
91CDX2_19796622_ChIP-Seq_MESCs_Mouse1.02188755
92AR_19668381_ChIP-Seq_PC3_Human1.01248943
93ARNT_22903824_ChIP-Seq_MCF-7_Human1.00958085
94ETV2_25802403_ChIP-Seq_MESCs_Mouse0.99652066
95SOX9_26525672_Chip-Seq_HEART_Mouse0.98674105
96MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.98539517
97NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98335531
98TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97720259
99CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.97232091
100KDM2B_26808549_Chip-Seq_REH_Human0.96701608
101SALL1_21062744_ChIP-ChIP_HESCs_Human0.96659471
102RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.96128445
103GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95785430
104EWS_26573619_Chip-Seq_HEK293_Human0.95704954
105YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93737774
106SOX2_16153702_ChIP-ChIP_HESCs_Human0.93582893
107BCAT_22108803_ChIP-Seq_LS180_Human0.93570144
108EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.93041157
109MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.91953539
110EST1_17652178_ChIP-ChIP_JURKAT_Human0.90624759
111CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.90401421
112TP53_18474530_ChIP-ChIP_U2OS_Human0.90105095
113FLI1_27457419_Chip-Seq_LIVER_Mouse0.89606877
114TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89491862
115POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89491862
116CBP_20019798_ChIP-Seq_JUKART_Human0.89234638
117IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.89234638
118AHR_22903824_ChIP-Seq_MCF-7_Human0.88750630

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.10290470
2MP0004859_abnormal_synaptic_plasticity4.51979619
3MP0003635_abnormal_synaptic_transmissio3.69703040
4MP0009745_abnormal_behavioral_response3.37390004
5MP0001968_abnormal_touch/_nociception3.19366760
6MP0002102_abnormal_ear_morphology3.17472786
7MP0009046_muscle_twitch3.17467416
8MP0002064_seizures3.16912106
9MP0002063_abnormal_learning/memory/cond3.02994473
10MP0004270_analgesia2.93008620
11MP0002572_abnormal_emotion/affect_behav2.84930761
12MP0002736_abnormal_nociception_after2.84692159
13MP0002822_catalepsy2.69702081
14MP0006276_abnormal_autonomic_nervous2.68944033
15MP0002272_abnormal_nervous_system2.64280550
16MP0002734_abnormal_mechanical_nocicepti2.54620364
17MP0002735_abnormal_chemical_nociception2.52341704
18MP0001501_abnormal_sleep_pattern2.49079221
19MP0001440_abnormal_grooming_behavior2.39114528
20MP0001529_abnormal_vocalization2.36340745
21MP0003122_maternal_imprinting2.35895352
22MP0001486_abnormal_startle_reflex2.28393875
23MP0005423_abnormal_somatic_nervous2.28381826
24MP0002067_abnormal_sensory_capabilities2.11140794
25MP0005645_abnormal_hypothalamus_physiol2.08836456
26MP0002733_abnormal_thermal_nociception2.05884377
27MP0005646_abnormal_pituitary_gland2.04790897
28MP0001970_abnormal_pain_threshold2.02924743
29MP0009780_abnormal_chondrocyte_physiolo1.88075405
30MP0002184_abnormal_innervation1.86939248
31MP0003787_abnormal_imprinting1.86064301
32MP0008789_abnormal_olfactory_epithelium1.80237412
33MP0001984_abnormal_olfaction1.80031026
34MP0004924_abnormal_behavior1.79331473
35MP0005386_behavior/neurological_phenoty1.79331473
36MP0001905_abnormal_dopamine_level1.79184839
37MP0002557_abnormal_social/conspecific_i1.77131714
38MP0004142_abnormal_muscle_tone1.76197045
39MP0002837_dystrophic_cardiac_calcinosis1.75375070
40MP0001188_hyperpigmentation1.69191023
41MP0000778_abnormal_nervous_system1.67763077
42MP0008995_early_reproductive_senescence1.61791495
43MP0003329_amyloid_beta_deposits1.54474394
44MP0000013_abnormal_adipose_tissue1.53168467
45MP0002876_abnormal_thyroid_physiology1.49203495
46MP0003879_abnormal_hair_cell1.46465193
47MP0008569_lethality_at_weaning1.45101832
48MP0010386_abnormal_urinary_bladder1.43022990
49MP0002909_abnormal_adrenal_gland1.41494401
50MP0000569_abnormal_digit_pigmentation1.40059160
51MP0004811_abnormal_neuron_physiology1.36125752
52MP0002066_abnormal_motor_capabilities/c1.34563762
53MP0001502_abnormal_circadian_rhythm1.34029022
54MP0004133_heterotaxia1.33590273
55MP0000955_abnormal_spinal_cord1.33263656
56MP0002882_abnormal_neuron_morphology1.30343478
57MP0000049_abnormal_middle_ear1.24936422
58MP0002234_abnormal_pharynx_morphology1.23719035
59MP0004858_abnormal_nervous_system1.17599990
60MP0003119_abnormal_digestive_system1.14856561
61MP0005551_abnormal_eye_electrophysiolog1.14603830
62MP0002653_abnormal_ependyma_morphology1.11463968
63MP0003938_abnormal_ear_development1.10225882
64MP0003861_abnormal_nervous_system1.05210140
65MP0003633_abnormal_nervous_system1.05128039
66MP0003183_abnormal_peptide_metabolism1.01066265
67MP0002638_abnormal_pupillary_reflex1.00811937
68MP0004742_abnormal_vestibular_system1.00288854
69MP0003121_genomic_imprinting0.98977444
70MP0000751_myopathy0.97912241
71MP0002152_abnormal_brain_morphology0.97067047
72MP0008872_abnormal_physiological_respon0.96939435
73MP0002069_abnormal_eating/drinking_beha0.96696093
74MP0002229_neurodegeneration0.96312390
75MP0000631_abnormal_neuroendocrine_gland0.95871269
76MP0004885_abnormal_endolymph0.93452640
77MP0003631_nervous_system_phenotype0.92722181
78MP0005379_endocrine/exocrine_gland_phen0.92426358
79MP0005394_taste/olfaction_phenotype0.91667518
80MP0005499_abnormal_olfactory_system0.91667518
81MP0001963_abnormal_hearing_physiology0.91105962
82MP0005535_abnormal_body_temperature0.87805680
83MP0006072_abnormal_retinal_apoptosis0.86087693
84MP0004145_abnormal_muscle_electrophysio0.86026016
85MP0001986_abnormal_taste_sensitivity0.85915298
86MP0001664_abnormal_digestion0.84424675
87MP0002752_abnormal_somatic_nervous0.82230414
88MP0002233_abnormal_nose_morphology0.82175034
89MP0004085_abnormal_heartbeat0.81368577
90MP0005084_abnormal_gallbladder_morpholo0.80710883
91MP0003698_abnormal_male_reproductive0.75828922
92MP0005171_absent_coat_pigmentation0.74983763
93MP0005195_abnormal_posterior_eye0.74640252
94MP0003634_abnormal_glial_cell0.73037615
95MP0004043_abnormal_pH_regulation0.71578763
96MP0005391_vision/eye_phenotype0.71129711
97MP0008874_decreased_physiological_sensi0.70356180
98MP0002163_abnormal_gland_morphology0.70137853
99MP0003567_abnormal_fetal_cardiomyocyte0.70042876
100MP0003123_paternal_imprinting0.69716958
101MP0006292_abnormal_olfactory_placode0.67374957
102MP0003011_delayed_dark_adaptation0.67178750
103MP0002938_white_spotting0.67139210
104MP0000026_abnormal_inner_ear0.66480583
105MP0008877_abnormal_DNA_methylation0.66215703
106MP0001293_anophthalmia0.66065410
107MP0004215_abnormal_myocardial_fiber0.65942307
108MP0000516_abnormal_urinary_system0.65554914
109MP0005367_renal/urinary_system_phenotyp0.65554914
110MP0002090_abnormal_vision0.64704185
111MP0010770_preweaning_lethality0.63695027
112MP0002082_postnatal_lethality0.63695027
113MP0002751_abnormal_autonomic_nervous0.63693531
114MP0003632_abnormal_nervous_system0.62988256
115MP0000604_amyloidosis0.61535307
116MP0006035_abnormal_mitochondrial_morpho0.61047045
117MP0005187_abnormal_penis_morphology0.60879498
118MP0003283_abnormal_digestive_organ0.60736248
119MP0001943_abnormal_respiration0.59841602
120MP0001177_atelectasis0.58617624
121MP0005409_darkened_coat_color0.57968997
122MP0004484_altered_response_of0.57562769
123MP0005253_abnormal_eye_physiology0.56414525
124MP0001485_abnormal_pinna_reflex0.54638015
125MP0004233_abnormal_muscle_weight0.53060097
126MP0002332_abnormal_exercise_endurance0.48687939

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.39240686
2Atonic seizures (HP:0010819)5.44837598
3Focal seizures (HP:0007359)5.06997770
4Epileptic encephalopathy (HP:0200134)4.77902899
5Febrile seizures (HP:0002373)4.73350895
6Myokymia (HP:0002411)4.65601021
7Visual hallucinations (HP:0002367)4.50873344
8Absence seizures (HP:0002121)4.33702073
9Hyperventilation (HP:0002883)4.20561025
10Dialeptic seizures (HP:0011146)4.01697771
11Progressive cerebellar ataxia (HP:0002073)3.73381833
12Generalized tonic-clonic seizures (HP:0002069)3.66600040
13Amyotrophic lateral sclerosis (HP:0007354)3.52756722
14Acute necrotizing encephalopathy (HP:0006965)3.40215607
15Gait imbalance (HP:0002141)3.30620487
16Polyphagia (HP:0002591)3.25720184
17Limb dystonia (HP:0002451)3.23501720
18Abnormal mitochondria in muscle tissue (HP:0008316)3.23106338
19Abnormal hair whorl (HP:0010721)3.18959352
20Broad-based gait (HP:0002136)3.16065156
21Pheochromocytoma (HP:0002666)3.11412574
22Intestinal atresia (HP:0011100)3.06555758
23Progressive macrocephaly (HP:0004481)3.05061154
24Medial flaring of the eyebrow (HP:0010747)3.00024736
25Congenital primary aphakia (HP:0007707)2.99317274
26Pancreatic fibrosis (HP:0100732)2.96306285
27Abnormal eating behavior (HP:0100738)2.94528933
28Neuroendocrine neoplasm (HP:0100634)2.89265518
29Cortical dysplasia (HP:0002539)2.85335775
30Tubulointerstitial nephritis (HP:0001970)2.83163178
31Nephrogenic diabetes insipidus (HP:0009806)2.82421475
32Progressive inability to walk (HP:0002505)2.82359030
33Anxiety (HP:0000739)2.78610741
34True hermaphroditism (HP:0010459)2.77323268
35Failure to thrive in infancy (HP:0001531)2.76833892
36Molar tooth sign on MRI (HP:0002419)2.74239172
37Abnormality of midbrain morphology (HP:0002418)2.74239172
38Truncal ataxia (HP:0002078)2.73933706
39Amblyopia (HP:0000646)2.73099038
40Pancreatic cysts (HP:0001737)2.72902530
41Epileptiform EEG discharges (HP:0011182)2.69722998
42Mitochondrial inheritance (HP:0001427)2.69346063
43Hip dysplasia (HP:0001385)2.63515005
44Lissencephaly (HP:0001339)2.60317688
45Excessive salivation (HP:0003781)2.58526604
46Drooling (HP:0002307)2.58526604
47Gaze-evoked nystagmus (HP:0000640)2.57430646
48Supranuclear gaze palsy (HP:0000605)2.55928442
49EEG with generalized epileptiform discharges (HP:0011198)2.53559496
50Acute encephalopathy (HP:0006846)2.52776957
51Poor suck (HP:0002033)2.50431900
52Nephronophthisis (HP:0000090)2.50151870
53Diplopia (HP:0000651)2.49969265
54Abnormality of binocular vision (HP:0011514)2.49969265
55Impaired vibration sensation in the lower limbs (HP:0002166)2.48486955
56Hypothermia (HP:0002045)2.47037429
57Atrophy/Degeneration involving motor neurons (HP:0007373)2.46738722
58Dysdiadochokinesis (HP:0002075)2.45762906
59Genital tract atresia (HP:0001827)2.44653408
60Hyperthyroidism (HP:0000836)2.43852897
61Depression (HP:0000716)2.42578361
62Vaginal atresia (HP:0000148)2.40782558
63Pachygyria (HP:0001302)2.39164102
64Abnormal ciliary motility (HP:0012262)2.38217296
65Poor eye contact (HP:0000817)2.37197268
66Oligodactyly (hands) (HP:0001180)2.36929715
67Hypsarrhythmia (HP:0002521)2.35620696
68Cerebral inclusion bodies (HP:0100314)2.34214953
69Specific learning disability (HP:0001328)2.32598605
70Protruding tongue (HP:0010808)2.28622490
71Aplasia/Hypoplasia of the brainstem (HP:0007362)2.28514655
72Hypoplasia of the brainstem (HP:0002365)2.28514655
73Dysmetria (HP:0001310)2.28231698
74Hemiparesis (HP:0001269)2.26913389
75Blue irides (HP:0000635)2.26712822
76Inability to walk (HP:0002540)2.25135617
77Neurofibrillary tangles (HP:0002185)2.22300182
78Ankle clonus (HP:0011448)2.21128973
79Abnormal social behavior (HP:0012433)2.20742888
80Impaired social interactions (HP:0000735)2.20742888
81Agitation (HP:0000713)2.19864182
82Increased CSF lactate (HP:0002490)2.19738882
83Esotropia (HP:0000565)2.19124868
84Absent speech (HP:0001344)2.16167969
85Abnormality of the metopic suture (HP:0005556)2.15828979
86Oligomenorrhea (HP:0000876)2.15292507
87Postaxial hand polydactyly (HP:0001162)2.14887786
88Optic nerve hypoplasia (HP:0000609)2.13871083
89Action tremor (HP:0002345)2.13754638
90Morphological abnormality of the pyramidal tract (HP:0002062)2.12339989
91Narrow nasal bridge (HP:0000446)2.12266921
92Insidious onset (HP:0003587)2.12195144
93Termporal pattern (HP:0011008)2.12195144
94Hypoventilation (HP:0002791)2.11484494
95Abnormal respiratory motile cilium physiology (HP:0012261)2.11415346
963-Methylglutaconic aciduria (HP:0003535)2.11117903
97Psychosis (HP:0000709)2.10544596
98Dynein arm defect of respiratory motile cilia (HP:0012255)2.10219029
99Absent/shortened dynein arms (HP:0200106)2.10219029
100Poor coordination (HP:0002370)2.09208435
101Optic disc pallor (HP:0000543)2.09034139
102Hepatocellular necrosis (HP:0001404)2.07959070
103Type II lissencephaly (HP:0007260)2.07352375
104Lipid accumulation in hepatocytes (HP:0006561)2.07227600
105Narrow forehead (HP:0000341)2.07208343
106Urinary urgency (HP:0000012)2.07123149
107Chronic hepatic failure (HP:0100626)2.06900259
108Sclerocornea (HP:0000647)2.06453512
109Abnormality of the corticospinal tract (HP:0002492)2.05427057
110Scanning speech (HP:0002168)2.05340314
111Spastic tetraplegia (HP:0002510)2.05225499
112Broad distal phalanx of finger (HP:0009836)2.04925239
113Urinary bladder sphincter dysfunction (HP:0002839)2.03890243
114Renal Fanconi syndrome (HP:0001994)2.02256878
115Fetal akinesia sequence (HP:0001989)2.01955024
116Muscular hypotonia of the trunk (HP:0008936)1.99757998
117Abnormality of the renal medulla (HP:0100957)1.98297384
118Bradykinesia (HP:0002067)1.97512415
119Sleep apnea (HP:0010535)1.95328496
120Abnormal respiratory motile cilium morphology (HP:0005938)1.95109720
121Abnormal respiratory epithelium morphology (HP:0012253)1.95109720
122Abnormality of the labia minora (HP:0012880)1.94815571
123Spastic gait (HP:0002064)1.93999162
124Anencephaly (HP:0002323)1.93992852
125Postaxial foot polydactyly (HP:0001830)1.93662255
126Hepatoblastoma (HP:0002884)1.93490756
127Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.91154283
128Degeneration of the lateral corticospinal tracts (HP:0002314)1.91154283
129Delusions (HP:0000746)1.89769522
130Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.88969239
131Short foot (HP:0001773)1.88729691
132Decreased testicular size (HP:0008734)1.87799879
133Mutism (HP:0002300)1.86716638
134Generalized myoclonic seizures (HP:0002123)1.86607239
135Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.85897786
136Occipital encephalocele (HP:0002085)1.84727091
137Retinal dysplasia (HP:0007973)1.83378009
138Growth hormone deficiency (HP:0000824)1.82764736
139Increased hepatocellular lipid droplets (HP:0006565)1.82535932
140Aplasia/Hypoplasia of the lens (HP:0008063)1.81740674
141Impaired smooth pursuit (HP:0007772)1.80198501
142Status epilepticus (HP:0002133)1.80195169
143Tented upper lip vermilion (HP:0010804)1.78017961
144Abnormality of salivation (HP:0100755)1.77187067
145Cystic liver disease (HP:0006706)1.76605562
146Prominent metopic ridge (HP:0005487)1.75580838
147Pendular nystagmus (HP:0012043)1.74356629
148Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.73699253
149High anterior hairline (HP:0009890)1.73563463
150Broad foot (HP:0001769)1.73498177
151Gastrointestinal atresia (HP:0002589)1.71345133

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.66740551
2NTRK34.31684635
3MAP3K123.61195047
4MAP3K43.27221368
5MAP4K23.18624776
6MAP2K73.17317519
7EPHA43.05000386
8DYRK22.75303328
9MAP3K92.71319083
10EPHA32.70326653
11MARK12.54038233
12PNCK2.42177206
13MINK12.26744385
14MAP2K42.10844087
15PLK21.95134064
16NTRK21.93269126
17TNIK1.86173710
18GRK51.74451539
19CDK191.72733770
20ARAF1.69636565
21DAPK21.66565785
22ERBB31.65050104
23RIPK41.63565148
24FRK1.62285655
25TRIM281.61127359
26DAPK11.55398382
27MAPK131.53485804
28AKT31.51180685
29NME11.43282254
30CSNK1G11.43116043
31PRPF4B1.39490436
32CSNK1A1L1.35382357
33PRKCG1.35053878
34NTRK11.32910322
35CDK51.28610614
36OXSR11.27430282
37WNK31.26706198
38CAMK2A1.22109926
39GRK71.21778779
40TSSK61.19300596
41FES1.12970174
42DYRK31.09965604
43UHMK11.09446514
44ADRBK21.06853574
45CAMK2B1.06537805
46PAK61.06055212
47KSR21.02033892
48KSR11.01654755
49BMPR20.99787347
50SIK20.99224492
51SGK2230.98981335
52SGK4940.98981335
53CAMKK20.95581841
54PRKCE0.91446103
55VRK10.89344856
56BRAF0.85835426
57SIK30.84574667
58SGK20.84408759
59BCR0.81048463
60PHKG10.80667766
61PHKG20.80667766
62CDK140.77063681
63CDK180.76521168
64PTK2B0.76340956
65BCKDK0.76303485
66MAP3K130.75027553
67CSNK1G20.74372051
68CAMK2D0.74174325
69NEK20.73596788
70DYRK1B0.73435395
71INSRR0.72625834
72TNK20.72548063
73EPHB10.72317966
74RPS6KA40.71913427
75DYRK1A0.71580335
76CDK150.71452199
77CCNB10.70401568
78FGR0.70385062
79ADRBK10.69751388
80CAMK40.67770032
81EPHB20.67698707
82CAMKK10.67086678
83TAOK10.66638801
84FER0.64148657
85PDK30.62282378
86PDK40.62282378
87GRK10.61778252
88TESK10.60802279
89PAK30.60579431
90CDK11A0.60377225
91CAMK2G0.60106095
92BMPR1B0.58470260
93SGK10.57901294
94TLK10.57656669
95MAP3K20.56159983
96IRAK10.56055497
97WNK40.56052163
98CAMK10.55117355
99IRAK20.54508796
100RPS6KA50.54201969
101MAPK150.51430056
102PRKG10.49959486
103SRPK10.49886260
104MUSK0.49867573
105CSNK1A10.49010765
106CSNK1G30.48614861
107MYLK0.47747322
108PRKCH0.46907315
109STK160.46849970
110PRKD30.46226332
111MAPKAPK50.45069772
112PRKACA0.45034772
113STK380.44478532
114STK110.43100321
115STK390.43098288
116LIMK10.41670205
117CSNK1D0.41226275
118LATS20.41147086
119ROCK20.40902181
120MAP2K10.39688250
121PKN10.38555889
122MAP3K50.38468005
123MAP3K10.38034060
124MAP3K60.37633856
125SGK30.36664838
126FGFR20.36423048
127RAF10.36352082
128PINK10.36140275
129RPS6KA30.35599372
130CSNK1E0.35353959
131GRK60.34717040
132PRKACB0.34412610
133MARK20.34375056
134PRKCZ0.34212456
135ZAK0.31222846
136CDK30.30017456
137MAPK40.28895635
138PRKCB0.28548151
139MAPK90.27857205
140PRKAA10.27486764
141AURKA0.27126734
142TYRO30.25584404

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.35517169
2Synaptic vesicle cycle_Homo sapiens_hsa047213.75906452
3Collecting duct acid secretion_Homo sapiens_hsa049663.19667283
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.88991961
5GABAergic synapse_Homo sapiens_hsa047272.82284605
6Oxidative phosphorylation_Homo sapiens_hsa001902.75846397
7Morphine addiction_Homo sapiens_hsa050322.52754116
8Amphetamine addiction_Homo sapiens_hsa050312.39888455
9Circadian entrainment_Homo sapiens_hsa047132.39121948
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.37224567
11Olfactory transduction_Homo sapiens_hsa047402.37097421
12Long-term potentiation_Homo sapiens_hsa047202.36525282
13Glutamatergic synapse_Homo sapiens_hsa047242.29221699
14Taste transduction_Homo sapiens_hsa047422.13433885
15Dopaminergic synapse_Homo sapiens_hsa047282.10641734
16Vibrio cholerae infection_Homo sapiens_hsa051102.07428823
17Parkinsons disease_Homo sapiens_hsa050122.03048385
18Serotonergic synapse_Homo sapiens_hsa047261.97825625
19Insulin secretion_Homo sapiens_hsa049111.89850619
20Alzheimers disease_Homo sapiens_hsa050101.86467561
21Salivary secretion_Homo sapiens_hsa049701.80523828
22Long-term depression_Homo sapiens_hsa047301.79673904
23Cocaine addiction_Homo sapiens_hsa050301.73199801
24Renin secretion_Homo sapiens_hsa049241.70255388
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.70233537
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.65245002
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.62263206
28Cholinergic synapse_Homo sapiens_hsa047251.60377875
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.57690809
30Calcium signaling pathway_Homo sapiens_hsa040201.50396261
31Gastric acid secretion_Homo sapiens_hsa049711.48983328
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.48771572
33Cardiac muscle contraction_Homo sapiens_hsa042601.47394298
34Huntingtons disease_Homo sapiens_hsa050161.42035776
35Basal transcription factors_Homo sapiens_hsa030221.37378342
36Aldosterone synthesis and secretion_Homo sapiens_hsa049251.36235828
37Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.34678762
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.33723689
39Oxytocin signaling pathway_Homo sapiens_hsa049211.29155173
40Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.21792352
41Phototransduction_Homo sapiens_hsa047441.14232764
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.12100551
43Gap junction_Homo sapiens_hsa045401.11247535
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.11053010
45GnRH signaling pathway_Homo sapiens_hsa049121.07967014
46Steroid biosynthesis_Homo sapiens_hsa001001.07160367
47Type I diabetes mellitus_Homo sapiens_hsa049400.99809553
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.99559071
49RNA polymerase_Homo sapiens_hsa030200.99278524
50Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.98703475
51Rheumatoid arthritis_Homo sapiens_hsa053230.97563632
52cAMP signaling pathway_Homo sapiens_hsa040240.94561152
53Axon guidance_Homo sapiens_hsa043600.89950236
54Estrogen signaling pathway_Homo sapiens_hsa049150.87980887
55Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.87512804
56Linoleic acid metabolism_Homo sapiens_hsa005910.87332387
57Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.87086055
58RNA degradation_Homo sapiens_hsa030180.84390652
59Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.83009432
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.81427475
61Melanogenesis_Homo sapiens_hsa049160.80308878
62Vascular smooth muscle contraction_Homo sapiens_hsa042700.79001866
63Hedgehog signaling pathway_Homo sapiens_hsa043400.75507973
64Peroxisome_Homo sapiens_hsa041460.74980740
65cGMP-PKG signaling pathway_Homo sapiens_hsa040220.73957404
66Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.73293902
67Type II diabetes mellitus_Homo sapiens_hsa049300.73000562
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71993067
69Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.70766360
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.69321398
71ErbB signaling pathway_Homo sapiens_hsa040120.67479487
72Phagosome_Homo sapiens_hsa041450.65422666
73Pancreatic secretion_Homo sapiens_hsa049720.64484877
74Oocyte meiosis_Homo sapiens_hsa041140.59586614
75Thyroid hormone synthesis_Homo sapiens_hsa049180.59372136
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58337504
77Fanconi anemia pathway_Homo sapiens_hsa034600.57956870
78Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.57896117
79Basal cell carcinoma_Homo sapiens_hsa052170.56352728
80SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56071471
81Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.56006774
82Glioma_Homo sapiens_hsa052140.55856241
83Alcoholism_Homo sapiens_hsa050340.55257693
84Butanoate metabolism_Homo sapiens_hsa006500.53355266
85Fatty acid metabolism_Homo sapiens_hsa012120.51897812
86Glucagon signaling pathway_Homo sapiens_hsa049220.51824920
87Propanoate metabolism_Homo sapiens_hsa006400.51259060
88Tryptophan metabolism_Homo sapiens_hsa003800.48879120
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.48352905
90Dilated cardiomyopathy_Homo sapiens_hsa054140.47377693
91Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.47136050
92Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.47085943
93MAPK signaling pathway_Homo sapiens_hsa040100.46113200
94Hippo signaling pathway_Homo sapiens_hsa043900.42260289
95Spliceosome_Homo sapiens_hsa030400.39396876
96Dorso-ventral axis formation_Homo sapiens_hsa043200.38876567
97Ras signaling pathway_Homo sapiens_hsa040140.38760710
98Circadian rhythm_Homo sapiens_hsa047100.38601060
99mRNA surveillance pathway_Homo sapiens_hsa030150.37931447
100Prion diseases_Homo sapiens_hsa050200.37661699
101Nitrogen metabolism_Homo sapiens_hsa009100.36311794
102Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36198342
103Phospholipase D signaling pathway_Homo sapiens_hsa040720.35895415
104Pyruvate metabolism_Homo sapiens_hsa006200.34943142
105Choline metabolism in cancer_Homo sapiens_hsa052310.34613474
106Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.34479839
107Non-homologous end-joining_Homo sapiens_hsa034500.33991827
108Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33891273
109Metabolic pathways_Homo sapiens_hsa011000.33469481
110Inositol phosphate metabolism_Homo sapiens_hsa005620.32318260
111Ovarian steroidogenesis_Homo sapiens_hsa049130.32025982
112African trypanosomiasis_Homo sapiens_hsa051430.31456718
113Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31018925
114Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.30790748
115Regulation of autophagy_Homo sapiens_hsa041400.26663461
116Wnt signaling pathway_Homo sapiens_hsa043100.25482597
117Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.25389919
118Selenocompound metabolism_Homo sapiens_hsa004500.25043080
119Fatty acid elongation_Homo sapiens_hsa000620.23726404
120Rap1 signaling pathway_Homo sapiens_hsa040150.20532884
121Tyrosine metabolism_Homo sapiens_hsa003500.20366109
122Fatty acid degradation_Homo sapiens_hsa000710.20044148
123Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.19771832
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.19516610
125Sphingolipid signaling pathway_Homo sapiens_hsa040710.19428161
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.19371055
127Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.19084711
128Protein export_Homo sapiens_hsa030600.18636740
129Purine metabolism_Homo sapiens_hsa002300.17101484
130Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.17051670
131Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.16860914
132Ether lipid metabolism_Homo sapiens_hsa005650.16053939
133Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.15885796
134Insulin signaling pathway_Homo sapiens_hsa049100.15863388
135Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.15692738

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