ZCCHC24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.24612803
2L-phenylalanine catabolic process (GO:0006559)5.24612803
3alpha-linolenic acid metabolic process (GO:0036109)5.21233469
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.93978292
5L-phenylalanine metabolic process (GO:0006558)4.93978292
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.66926084
7aromatic amino acid family catabolic process (GO:0009074)4.35098488
8negative regulation of fibrinolysis (GO:0051918)4.34478323
9complement activation, alternative pathway (GO:0006957)4.14666915
10protein carboxylation (GO:0018214)4.12258527
11peptidyl-glutamic acid carboxylation (GO:0017187)4.12258527
12regulation of protein activation cascade (GO:2000257)4.10759246
13positive regulation of fatty acid beta-oxidation (GO:0032000)4.09031871
14bile acid biosynthetic process (GO:0006699)4.08813603
15regulation of fibrinolysis (GO:0051917)3.98479184
16regulation of complement activation (GO:0030449)3.92194889
17glyoxylate metabolic process (GO:0046487)3.92112606
18synaptic vesicle docking involved in exocytosis (GO:0016081)3.91345045
19kynurenine metabolic process (GO:0070189)3.85772451
20sulfur amino acid catabolic process (GO:0000098)3.85729970
21high-density lipoprotein particle remodeling (GO:0034375)3.68972126
22protein heterotrimerization (GO:0070208)3.68824298
23fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.65818641
24urea metabolic process (GO:0019627)3.62055664
25urea cycle (GO:0000050)3.62055664
26tryptophan catabolic process (GO:0006569)3.56046122
27indole-containing compound catabolic process (GO:0042436)3.56046122
28indolalkylamine catabolic process (GO:0046218)3.56046122
29regulation of triglyceride catabolic process (GO:0010896)3.55703400
30lysine catabolic process (GO:0006554)3.53959616
31lysine metabolic process (GO:0006553)3.53959616
32cellular potassium ion homeostasis (GO:0030007)3.53421163
33positive regulation of fatty acid oxidation (GO:0046321)3.52887086
34dicarboxylic acid biosynthetic process (GO:0043650)3.50379002
35extracellular matrix assembly (GO:0085029)3.48266134
36plasma lipoprotein particle clearance (GO:0034381)3.47464312
37dermatan sulfate biosynthetic process (GO:0030208)3.47073293
38regulation of fatty acid beta-oxidation (GO:0031998)3.43864455
39bile acid metabolic process (GO:0008206)3.43181785
40positive regulation of lipid catabolic process (GO:0050996)3.42177192
41reverse cholesterol transport (GO:0043691)3.39371244
42axon ensheathment in central nervous system (GO:0032291)3.39303379
43central nervous system myelination (GO:0022010)3.39303379
44glutamate metabolic process (GO:0006536)3.39056030
45dermatan sulfate metabolic process (GO:0030205)3.38111542
46regulation of cholesterol esterification (GO:0010872)3.35850556
47tryptophan metabolic process (GO:0006568)3.35317149
48cysteine metabolic process (GO:0006534)3.33714415
49coenzyme catabolic process (GO:0009109)3.33306352
50sodium ion export (GO:0071436)3.33183827
51epoxygenase P450 pathway (GO:0019373)3.33147002
52cell migration involved in heart development (GO:0060973)3.32004287
53plasma lipoprotein particle remodeling (GO:0034369)3.28780457
54protein-lipid complex remodeling (GO:0034368)3.28780457
55macromolecular complex remodeling (GO:0034367)3.28780457
56nitrogen cycle metabolic process (GO:0071941)3.26557501
57cellular modified amino acid catabolic process (GO:0042219)3.26536382
58cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.25280342
59triglyceride homeostasis (GO:0070328)3.23463481
60acylglycerol homeostasis (GO:0055090)3.23463481
61alpha-amino acid catabolic process (GO:1901606)3.22134742
62regulation of cholesterol homeostasis (GO:2000188)3.19999984
63homocysteine metabolic process (GO:0050667)3.17574128
64peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)3.17468564
65cellular ketone body metabolic process (GO:0046950)3.14992657
66amino-acid betaine metabolic process (GO:0006577)3.14915426
67serine family amino acid catabolic process (GO:0009071)3.14589505
68negative regulation of protein activation cascade (GO:2000258)3.11665537
69tyrosine metabolic process (GO:0006570)3.11656099
70acetyl-CoA metabolic process (GO:0006084)3.10502017
71chondroitin sulfate catabolic process (GO:0030207)3.09257742
72cellular amino acid catabolic process (GO:0009063)3.08030933
73regulation of plasminogen activation (GO:0010755)3.05843769
74negative regulation of cholesterol transport (GO:0032375)3.04302262
75negative regulation of sterol transport (GO:0032372)3.04302262
76extracellular fibril organization (GO:0043206)3.01867516
77ethanol oxidation (GO:0006069)3.00838779
78phospholipid efflux (GO:0033700)3.00607135
79aspartate family amino acid catabolic process (GO:0009068)2.99731837
80collagen fibril organization (GO:0030199)2.97862306
81short-chain fatty acid metabolic process (GO:0046459)2.97583633
82phospholipid homeostasis (GO:0055091)2.96263784
83membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.95631915
84aromatic amino acid family metabolic process (GO:0009072)2.95260456
85cell communication by electrical coupling (GO:0010644)2.94931502
86fibrinolysis (GO:0042730)2.94533058
87postsynaptic membrane organization (GO:0001941)2.93553151
88glutamate secretion (GO:0014047)2.90097061
89positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.89415082
90cholesterol efflux (GO:0033344)2.87841075
91positive regulation of fatty acid metabolic process (GO:0045923)2.87326804
92myelination in peripheral nervous system (GO:0022011)2.86454706
93peripheral nervous system axon ensheathment (GO:0032292)2.86454706
94dicarboxylic acid catabolic process (GO:0043649)2.85823577
95barbed-end actin filament capping (GO:0051016)2.85715141
962-oxoglutarate metabolic process (GO:0006103)2.85509354
97cardiac myofibril assembly (GO:0055003)2.84909607
98fatty acid transmembrane transport (GO:1902001)2.84649474
99regulation of fatty acid oxidation (GO:0046320)2.84311299
100fatty acid beta-oxidation (GO:0006635)2.83961384
101cellular glucuronidation (GO:0052695)2.83802633
102negative regulation of lipase activity (GO:0060192)2.83078350
103very long-chain fatty acid metabolic process (GO:0000038)2.82745850
104protein-lipid complex assembly (GO:0065005)2.81804065
105linoleic acid metabolic process (GO:0043651)2.81050507
106low-density lipoprotein particle remodeling (GO:0034374)2.80561380
107cGMP-mediated signaling (GO:0019934)2.79524299
108amino acid import (GO:0043090)2.76521958
109metanephric mesenchyme development (GO:0072075)2.75888263
110complement activation (GO:0006956)2.75455819
111fatty acid oxidation (GO:0019395)2.73885225
112regulation of cholesterol biosynthetic process (GO:0045540)2.73820596
113plasma lipoprotein particle assembly (GO:0034377)2.73625109
114kidney mesenchyme development (GO:0072074)2.73589070
115opsonization (GO:0008228)2.73253252
116L-amino acid import (GO:0043092)2.72622849
117regulation of cholesterol metabolic process (GO:0090181)2.71788568
118regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.71613909
119positive regulation of triglyceride metabolic process (GO:0090208)2.71587228
120astrocyte differentiation (GO:0048708)2.71241155
121lipid oxidation (GO:0034440)2.70866039
122monocarboxylic acid catabolic process (GO:0072329)2.70764469
123cholesterol homeostasis (GO:0042632)2.70215212
124organic acid catabolic process (GO:0016054)2.70102558
125carboxylic acid catabolic process (GO:0046395)2.70102558
126arginine metabolic process (GO:0006525)2.68579861
127ketone body metabolic process (GO:1902224)2.68378605
128locomotory exploration behavior (GO:0035641)2.67809211
129fatty acid catabolic process (GO:0009062)2.67322152
130sterol homeostasis (GO:0055092)2.66995568
131cerebellar granule cell differentiation (GO:0021707)2.65843451
132midgut development (GO:0007494)2.64285813
133acylglycerol catabolic process (GO:0046464)2.63684967
134synaptic vesicle maturation (GO:0016188)2.63238993
135cytoskeletal anchoring at plasma membrane (GO:0007016)2.62421047
136regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.62395050
137regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.61203610
138vascular endothelial growth factor signaling pathway (GO:0038084)2.58548940
139myofibril assembly (GO:0030239)2.57222214
140astrocyte development (GO:0014002)2.56969872
141potassium ion homeostasis (GO:0055075)2.55044172
142cellular response to epinephrine stimulus (GO:0071872)2.54292066
143negative regulation of catenin import into nucleus (GO:0035414)2.53327797
144regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.52946139
145chondrocyte proliferation (GO:0035988)2.51064955
146fibril organization (GO:0097435)2.50878421
147activation of protein kinase A activity (GO:0034199)2.45078959
148actin-myosin filament sliding (GO:0033275)2.43311126
149muscle filament sliding (GO:0030049)2.43311126
150negative regulation of protein localization to cell surface (GO:2000009)2.42778290
151neuronal ion channel clustering (GO:0045161)2.40347418
152protein targeting to plasma membrane (GO:0072661)2.39744075
153regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.39234489
154potassium ion import (GO:0010107)2.38876428
155endodermal cell differentiation (GO:0035987)2.38758046
156basement membrane organization (GO:0071711)2.37778892
157cellular response to catecholamine stimulus (GO:0071870)2.37210912
158cellular response to monoamine stimulus (GO:0071868)2.37210912
159regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.36233267
160type B pancreatic cell proliferation (GO:0044342)2.35916640
161adherens junction assembly (GO:0034333)2.34916736
162cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.34760918
163negative regulation of smooth muscle cell migration (GO:0014912)2.34379540
164adhesion of symbiont to host cell (GO:0044650)2.33907655
165virion attachment to host cell (GO:0019062)2.33907655
166regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.31738870
167positive regulation of osteoblast proliferation (GO:0033690)2.31388035
168synaptic vesicle exocytosis (GO:0016079)2.31290778
169cortical actin cytoskeleton organization (GO:0030866)2.31036675
170regulation of short-term neuronal synaptic plasticity (GO:0048172)2.29091150
171axon ensheathment (GO:0008366)2.27500327
172ensheathment of neurons (GO:0007272)2.27500327
173apoptotic cell clearance (GO:0043277)2.26308763
174cell-substrate adherens junction assembly (GO:0007045)2.25509587
175focal adhesion assembly (GO:0048041)2.25509587
176stress fiber assembly (GO:0043149)2.23609918
177import into cell (GO:0098657)2.23059027
178regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.22655277
179positive regulation of fibroblast migration (GO:0010763)2.22612067
180regulation of the force of heart contraction (GO:0002026)2.22154458
181myelination (GO:0042552)2.21768714
182regulation of synaptic vesicle exocytosis (GO:2000300)2.20471782
183regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.20293605
184neuromuscular process controlling balance (GO:0050885)2.20213629
185membrane assembly (GO:0071709)2.19605992
186regulation of extracellular matrix disassembly (GO:0010715)2.19022126
187actin-mediated cell contraction (GO:0070252)2.19008459
188axon extension involved in axon guidance (GO:0048846)2.18623926
189neuron projection extension involved in neuron projection guidance (GO:1902284)2.18623926
190cardiac muscle hypertrophy (GO:0003300)2.17063650
191positive regulation of extracellular matrix organization (GO:1903055)2.17006217
192bone trabecula formation (GO:0060346)2.16956305
193positive regulation of receptor recycling (GO:0001921)2.16617117
194cortical cytoskeleton organization (GO:0030865)2.16090800
195chondroitin sulfate biosynthetic process (GO:0030206)2.16012893
196cell volume homeostasis (GO:0006884)2.15076130
197cardiac muscle adaptation (GO:0014887)2.15028251
198cardiac muscle hypertrophy in response to stress (GO:0014898)2.15028251
199muscle hypertrophy in response to stress (GO:0003299)2.15028251
200cardiac muscle contraction (GO:0060048)2.14753948

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse6.64070911
2* RXR_22158963_ChIP-Seq_LIVER_Mouse4.66811983
3PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.29988638
4LXR_22158963_ChIP-Seq_LIVER_Mouse3.93284688
5PPARA_22158963_ChIP-Seq_LIVER_Mouse3.90177085
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.87359804
7NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.86047647
8EGR1_23403033_ChIP-Seq_LIVER_Mouse2.70456559
9TRIM28_21343339_ChIP-Seq_HEK293_Human2.45918650
10CLOCK_20551151_ChIP-Seq_293T_Human2.15136299
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.06998766
12TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.93105486
13PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.91244650
14ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.82256358
15THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.67201198
16SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.66782110
17CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.60537180
18EZH2_18974828_ChIP-Seq_MESCs_Mouse1.57172001
19RNF2_18974828_ChIP-Seq_MESCs_Mouse1.57172001
20ESR2_21235772_ChIP-Seq_MCF-7_Human1.53321015
21* FOXA2_19822575_ChIP-Seq_HepG2_Human1.51582762
22EED_16625203_ChIP-ChIP_MESCs_Mouse1.36933397
23SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.36637683
24MTF2_20144788_ChIP-Seq_MESCs_Mouse1.36385826
25EP300_21415370_ChIP-Seq_HL-1_Mouse1.36262086
26AR_21572438_ChIP-Seq_LNCaP_Human1.36149862
27NRF2_20460467_ChIP-Seq_MEFs_Mouse1.34327720
28NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.34327720
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.34274060
30SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.33658442
31BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.33644583
32RARB_27405468_Chip-Seq_BRAIN_Mouse1.32031250
33TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.31964355
34DROSHA_22980978_ChIP-Seq_HELA_Human1.30539886
35SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.27600319
36SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.26687773
37WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.25378021
38ZFP281_27345836_Chip-Seq_ESCs_Mouse1.24166133
39CDX2_19796622_ChIP-Seq_MESCs_Mouse1.22766601
40* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.22437684
41SMAD_19615063_ChIP-ChIP_OVARY_Human1.21217083
42* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.18563405
43JARID2_20075857_ChIP-Seq_MESCs_Mouse1.18485518
44SMC1_22415368_ChIP-Seq_MEFs_Mouse1.16372242
45SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.16050325
46MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.15671917
47TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.15254237
48* TP53_23651856_ChIP-Seq_MEFs_Mouse1.14754334
49NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.14535971
50ELK3_25401928_ChIP-Seq_HUVEC_Human1.11225225
51TET1_21490601_ChIP-Seq_MESCs_Mouse1.10734265
52EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.10699250
53NR3C1_23031785_ChIP-Seq_PC12_Mouse1.10310321
54UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.09709869
55SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.08913567
56ERG_21242973_ChIP-ChIP_JURKAT_Human1.08860150
57TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.08675650
58* TBX20_22080862_ChIP-Seq_HEART_Mouse1.08087023
59* TBX20_22328084_ChIP-Seq_HEART_Mouse1.08087023
60CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07953392
61RING1B_27294783_Chip-Seq_NPCs_Mouse1.07641495
62SMC3_22415368_ChIP-Seq_MEFs_Mouse1.07520101
63JARID2_20064375_ChIP-Seq_MESCs_Mouse1.06921556
64STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.06250483
65RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.05099617
66ZNF217_24962896_ChIP-Seq_MCF-7_Human1.04231107
67OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.03936540
68CJUN_26792858_Chip-Seq_BT549_Human1.02140192
69* CTCF_27219007_Chip-Seq_Bcells_Human1.01749034
70* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.01379559
71PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.01238285
72CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.01128423
73PPAR_26484153_Chip-Seq_NCI-H1993_Human1.00801889
74PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.99595940
75EZH2_27294783_Chip-Seq_ESCs_Mouse0.99241092
76FOXO3_23340844_ChIP-Seq_DLD1_Human0.97533192
77CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.97259489
78GATA2_21666600_ChIP-Seq_HMVEC_Human0.97114247
79ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.96850470
80ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.96734168
81CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.95275129
82SA1_22415368_ChIP-Seq_MEFs_Mouse0.94930735
83EZH2_27304074_Chip-Seq_ESCs_Mouse0.94295863
84* KDM2B_26808549_Chip-Seq_K562_Human0.93662994
85ESR1_15608294_ChIP-ChIP_MCF-7_Human0.93457620
86GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.93092631
87ESR1_21235772_ChIP-Seq_MCF-7_Human0.92247118
88TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.91553992
89ZFP281_18757296_ChIP-ChIP_E14_Mouse0.90453702
90DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90356490
91* LXR_22292898_ChIP-Seq_THP-1_Human0.90299292
92P300_27058665_Chip-Seq_ZR-75-30cells_Human0.89470259
93SUZ12_27294783_Chip-Seq_ESCs_Mouse0.88495210
94RNF2_27304074_Chip-Seq_ESCs_Mouse0.88485479
95* KDM2B_26808549_Chip-Seq_DND41_Human0.87820082
96TP53_20018659_ChIP-ChIP_R1E_Mouse0.87566832
97YAP1_20516196_ChIP-Seq_MESCs_Mouse0.85798988
98* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.85289300
99NFIB_24661679_ChIP-Seq_LUNG_Mouse0.85283184
100RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.85112664
101WT1_19549856_ChIP-ChIP_CCG9911_Human0.84307457
102IKZF1_21737484_ChIP-ChIP_HCT116_Human0.83812931
103KDM2B_26808549_Chip-Seq_SUP-B15_Human0.83593250
104PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.83571554
105EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.83253683
106TP63_17297297_ChIP-ChIP_HaCaT_Human0.83207636
107* HNF4A_19822575_ChIP-Seq_HepG2_Human0.82426695
108* RACK7_27058665_Chip-Seq_MCF-7_Human0.82338612
109SALL4_18804426_ChIP-ChIP_XEN_Mouse0.82023385
110SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.81203003
111RXR_22108803_ChIP-Seq_LS180_Human0.80914204
112EZH2_22144423_ChIP-Seq_EOC_Human0.80749646
113PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.80433107
114EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.79574617
115PIAS1_25552417_ChIP-Seq_VCAP_Human0.78654119
116TP53_16413492_ChIP-PET_HCT116_Human0.77112517
117* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.76651599
118* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.76435211
119DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.76382726
120SOX9_24532713_ChIP-Seq_HFSC_Mouse0.76242020
121BCAT_22108803_ChIP-Seq_LS180_Human0.76130556
122RING1B_27294783_Chip-Seq_ESCs_Mouse0.75189004
123GBX2_23144817_ChIP-Seq_PC3_Human0.75155174
124ISL1_27105846_Chip-Seq_CPCs_Mouse0.75113532
125SMAD4_21741376_ChIP-Seq_HESCs_Human0.74940172
126GATA1_19941826_ChIP-Seq_K562_Human0.74455994
127ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.74097504
128SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.73808680

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system5.45638274
2MP0005360_urolithiasis5.13625253
3MP0008438_abnormal_cutaneous_collagen4.31892866
4MP0005085_abnormal_gallbladder_physiolo3.98845448
5MP0005365_abnormal_bile_salt3.84357525
6MP0003705_abnormal_hypodermis_morpholog3.31193263
7MP0008875_abnormal_xenobiotic_pharmacok3.11967226
8MP0003252_abnormal_bile_duct2.95008463
9MP0010329_abnormal_lipoprotein_level2.74102963
10MP0009840_abnormal_foam_cell2.46148087
11MP0005275_abnormal_skin_tensile2.33917812
12MP0003806_abnormal_nucleotide_metabolis2.33788303
13MP0005503_abnormal_tendon_morphology2.14370954
14MP0005083_abnormal_biliary_tract1.93686446
15MP0004130_abnormal_muscle_cell1.93223845
16MP0005332_abnormal_amino_acid1.92302693
17MP0003195_calcinosis1.84196442
18MP0003279_aneurysm1.81939545
19MP0003191_abnormal_cellular_cholesterol1.78105127
20MP0002118_abnormal_lipid_homeostasis1.77988855
21MP0002837_dystrophic_cardiac_calcinosis1.71838679
22MP0003690_abnormal_glial_cell1.71457591
23MP0009384_cardiac_valve_regurgitation1.67191231
24MP0010368_abnormal_lymphatic_system1.63575895
25MP0004270_analgesia1.62466320
26MP0004272_abnormal_basement_membrane1.60467020
27MP0005670_abnormal_white_adipose1.57193046
28MP0005257_abnormal_intraocular_pressure1.55422962
29MP0000751_myopathy1.55330866
30MP0001958_emphysema1.54675293
31MP0005623_abnormal_meninges_morphology1.46457067
32MP0003635_abnormal_synaptic_transmissio1.43462767
33MP0005423_abnormal_somatic_nervous1.41815095
34MP0000609_abnormal_liver_physiology1.39037313
35MP0001666_abnormal_nutrient_absorption1.36369279
36MP0003329_amyloid_beta_deposits1.28200555
37MP0002108_abnormal_muscle_morphology1.27530472
38MP0005584_abnormal_enzyme/coenzyme_acti1.27225742
39MP0003566_abnormal_cell_adhesion1.26649486
40MP0005171_absent_coat_pigmentation1.25340287
41MP0005666_abnormal_adipose_tissue1.25295600
42MP0008569_lethality_at_weaning1.24102844
43MP0001542_abnormal_bone_strength1.18217441
44MP0009780_abnormal_chondrocyte_physiolo1.17986188
45MP0000604_amyloidosis1.17732616
46MP0003879_abnormal_hair_cell1.16903125
47MP0002064_seizures1.15770129
48MP0002971_abnormal_brown_adipose1.15714019
49MP0000920_abnormal_myelination1.13155398
50MP0005319_abnormal_enzyme/_coenzyme1.08587850
51MP0002063_abnormal_learning/memory/cond1.05426310
52MP0003880_abnormal_central_pattern1.05035975
53MP0004185_abnormal_adipocyte_glucose1.04872620
54MP0000747_muscle_weakness1.04434742
55MP0004087_abnormal_muscle_fiber1.04119167
56MP0005375_adipose_tissue_phenotype1.03980251
57MP0001486_abnormal_startle_reflex1.01558839
58MP0002972_abnormal_cardiac_muscle0.99618365
59MP0002133_abnormal_respiratory_system0.98235167
60MP0005388_respiratory_system_phenotype0.98235167
61MP0000733_abnormal_muscle_development0.97941486
62MP0002734_abnormal_mechanical_nocicepti0.96969612
63MP0002106_abnormal_muscle_physiology0.96032488
64MP0002249_abnormal_larynx_morphology0.95854525
65MP0006138_congestive_heart_failure0.95299853
66MP0004858_abnormal_nervous_system0.95215839
67MP0002272_abnormal_nervous_system0.95173132
68MP0003868_abnormal_feces_composition0.94885367
69MP0002295_abnormal_pulmonary_circulatio0.94828759
70MP0000013_abnormal_adipose_tissue0.94106042
71MP0005409_darkened_coat_color0.94077281
72MP0005167_abnormal_blood-brain_barrier0.93103892
73MP0004510_myositis0.93013442
74MP0010030_abnormal_orbit_morphology0.92710860
75MP0000003_abnormal_adipose_tissue0.92566428
76MP0003828_pulmonary_edema0.91211504
77MP0000749_muscle_degeneration0.90952641
78MP0005330_cardiomyopathy0.90527044
79MP0002060_abnormal_skin_morphology0.90428120
80MP0002168_other_aberrant_phenotype0.89772794
81MP0001502_abnormal_circadian_rhythm0.89568891
82MP0004019_abnormal_vitamin_homeostasis0.89288398
83MP0002269_muscular_atrophy0.87602869
84MP0004215_abnormal_myocardial_fiber0.87037299
85MP0001348_abnormal_lacrimal_gland0.86577026
86MP0004145_abnormal_muscle_electrophysio0.86572127
87MP0003950_abnormal_plasma_membrane0.86363824
88MP0000759_abnormal_skeletal_muscle0.83673620
89MP0006054_spinal_hemorrhage0.82256947
90MP0003075_altered_response_to0.82231813
91MP0005595_abnormal_vascular_smooth0.81386554
92MP0004036_abnormal_muscle_relaxation0.79634090
93MP0000767_abnormal_smooth_muscle0.79103964
94MP0000762_abnormal_tongue_morphology0.78718251
95MP0003091_abnormal_cell_migration0.78680166
96MP0001177_atelectasis0.78505347
97MP0005165_increased_susceptibility_to0.77823115
98MP0005508_abnormal_skeleton_morphology0.77181089
99MP0000163_abnormal_cartilage_morphology0.76256834
100MP0003942_abnormal_urinary_system0.75159626
101MP0002896_abnormal_bone_mineralization0.74799450
102MP0009053_abnormal_anal_canal0.73899476
103MP0009745_abnormal_behavioral_response0.73560084
104MP0009250_abnormal_appendicular_skeleto0.73088698
105MP0005334_abnormal_fat_pad0.73065819
106MP0003385_abnormal_body_wall0.72812042
107MP0005620_abnormal_muscle_contractility0.72290070
108MP0005023_abnormal_wound_healing0.71863372
109MP0004883_abnormal_blood_vessel0.71859984
110MP0001879_abnormal_lymphatic_vessel0.71620914
111MP0000428_abnormal_craniofacial_morphol0.71074116
112MP0001299_abnormal_eye_distance/0.69905464
113MP0002128_abnormal_blood_circulation0.68876138
114MP0002115_abnormal_skeleton_extremities0.68754621
115MP0002254_reproductive_system_inflammat0.68066759
116MP0005248_abnormal_Harderian_gland0.67851103
117MP0000598_abnormal_liver_morphology0.67573971
118MP0003045_fibrosis0.67006461
119MP0003011_delayed_dark_adaptation0.65229758
120MP0005164_abnormal_response_to0.64681998
121MP0004084_abnormal_cardiac_muscle0.64548698
122MP0004885_abnormal_endolymph0.64506442
123MP0005647_abnormal_sex_gland0.64447731
124MP0000534_abnormal_ureter_morphology0.63981068
125MP0003115_abnormal_respiratory_system0.63871212
126MP0003633_abnormal_nervous_system0.63688533
127MP0003656_abnormal_erythrocyte_physiolo0.63683897
128MP0010630_abnormal_cardiac_muscle0.63672091
129MP0000639_abnormal_adrenal_gland0.63561426
130MP0005369_muscle_phenotype0.63201132
131MP0000750_abnormal_muscle_regeneration0.62770356
132MP0004859_abnormal_synaptic_plasticity0.61386726
133MP0003634_abnormal_glial_cell0.61235075
134MP0005385_cardiovascular_system_phenoty0.61134443
135MP0001544_abnormal_cardiovascular_syste0.61134443

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)5.79535882
2Xanthomatosis (HP:0000991)4.62109146
3Intrahepatic cholestasis (HP:0001406)4.38068887
4Abnormality of aromatic amino acid family metabolism (HP:0004338)4.26940744
5Complement deficiency (HP:0004431)4.24101455
6Hyperlipoproteinemia (HP:0010980)4.16401294
7Protrusio acetabuli (HP:0003179)4.04491628
8Premature rupture of membranes (HP:0001788)3.72672330
9Abnormality of monocarboxylic acid metabolism (HP:0010996)3.67719889
10Vascular tortuosity (HP:0004948)3.63981816
11Hypoalphalipoproteinemia (HP:0003233)3.59235191
12Broad metatarsal (HP:0001783)3.53989404
13Prolonged partial thromboplastin time (HP:0003645)3.52324513
14Hypobetalipoproteinemia (HP:0003563)3.44301835
15Epidermoid cyst (HP:0200040)3.29638022
16Hypolipoproteinemia (HP:0010981)3.28349057
17Arterial tortuosity (HP:0005116)3.18659518
18Hyperammonemia (HP:0001987)3.14870113
19Obstructive sleep apnea (HP:0002870)3.09033558
20Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.07373462
21Abnormality of complement system (HP:0005339)3.04964046
22Abnormality of the common coagulation pathway (HP:0010990)3.00369682
23Ketosis (HP:0001946)2.99677862
24Shallow orbits (HP:0000586)2.93512157
25Abnormality of serine family amino acid metabolism (HP:0010894)2.87772220
26Abnormality of glycine metabolism (HP:0010895)2.87772220
27Type 1 muscle fiber predominance (HP:0003803)2.81716450
28Hyperglycinemia (HP:0002154)2.80587076
29Myocardial infarction (HP:0001658)2.77970887
30Peritonitis (HP:0002586)2.75949420
31Wormian bones (HP:0002645)2.73636457
32Turricephaly (HP:0000262)2.73212848
33Vertebral compression fractures (HP:0002953)2.68000053
34Mildly elevated creatine phosphokinase (HP:0008180)2.63525072
35Neonatal short-limb short stature (HP:0008921)2.63052216
36Skin nodule (HP:0200036)2.62512296
37Mitral regurgitation (HP:0001653)2.62273718
38Mitral stenosis (HP:0001718)2.60261280
39Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.59021648
40Hyperglycinuria (HP:0003108)2.56644328
41Muscle fiber inclusion bodies (HP:0100299)2.55615232
42Abnormality of glutamine family amino acid metabolism (HP:0010902)2.54373582
43Hypoglycemic coma (HP:0001325)2.52800602
44Fragile skin (HP:0001030)2.52227382
45Joint hemorrhage (HP:0005261)2.52140512
46Nemaline bodies (HP:0003798)2.50515908
47Abnormality of the Achilles tendon (HP:0005109)2.45002006
48Hypercholesterolemia (HP:0003124)2.43543931
49Atrophic scars (HP:0001075)2.43254658
50Aortic dissection (HP:0002647)2.38779399
51Bowel diverticulosis (HP:0005222)2.38571623
52Increased variability in muscle fiber diameter (HP:0003557)2.37865698
53Ankle contracture (HP:0006466)2.32862975
54Cervical subluxation (HP:0003308)2.32065075
55Abnormality of sulfur amino acid metabolism (HP:0004339)2.31814213
56Cerebral aneurysm (HP:0004944)2.31349179
57Mitral valve prolapse (HP:0001634)2.24888263
58Exercise-induced myalgia (HP:0003738)2.22519269
59Abnormality of methionine metabolism (HP:0010901)2.22115464
60Bundle branch block (HP:0011710)2.22046182
61Delayed CNS myelination (HP:0002188)2.21579759
62Hyporeflexia of lower limbs (HP:0002600)2.21541101
63Ketoacidosis (HP:0001993)2.21001658
64Coronal craniosynostosis (HP:0004440)2.20357779
65Infantile muscular hypotonia (HP:0008947)2.19503246
66Abnormality of aspartate family amino acid metabolism (HP:0010899)2.18427639
67Abnormality of the intrinsic pathway (HP:0010989)2.18156835
68Distal lower limb muscle weakness (HP:0009053)2.16922936
69Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.15776345
70Increased connective tissue (HP:0009025)2.14638017
71Hypoplasia of the iris (HP:0007676)2.14562426
72Genu recurvatum (HP:0002816)2.11692287
73Abnormality of fatty-acid metabolism (HP:0004359)2.11092393
74Hypoventilation (HP:0002791)2.08693615
75Abnormality of dentin (HP:0010299)2.08455652
76Bladder diverticulum (HP:0000015)2.06640818
77Cardiovascular calcification (HP:0011915)2.05429660
78Achilles tendon contracture (HP:0001771)2.05035067
79Fat malabsorption (HP:0002630)2.04050023
80Ulnar bowing (HP:0003031)2.02053359
81Myoglobinuria (HP:0002913)2.01292893
82Neurofibrillary tangles (HP:0002185)2.01127562
83Abnormality of skeletal muscle fiber size (HP:0012084)2.01050785
84Amyloidosis (HP:0011034)2.00355625
85Systemic lupus erythematosus (HP:0002725)1.98783237
86Limited hip movement (HP:0008800)1.98736338
87Centrally nucleated skeletal muscle fibers (HP:0003687)1.98681796
88Neck muscle weakness (HP:0000467)1.98148637
89EMG: myopathic abnormalities (HP:0003458)1.96555400
90Difficulty running (HP:0009046)1.95653958
91Asymmetric septal hypertrophy (HP:0001670)1.95292747
92Aortic regurgitation (HP:0001659)1.93699144
93Round ear (HP:0100830)1.93601749
94Back pain (HP:0003418)1.92553974
95Cholelithiasis (HP:0001081)1.92476502
96Mild short stature (HP:0003502)1.92208176
97Ectopia lentis (HP:0001083)1.91986352
98Spastic diplegia (HP:0001264)1.91953782
99Insomnia (HP:0100785)1.91463924
100Aortic aneurysm (HP:0004942)1.91198458
101Hepatocellular carcinoma (HP:0001402)1.91105298
102Distal arthrogryposis (HP:0005684)1.90966903
103Spinal rigidity (HP:0003306)1.90112586
104Abnormal atrioventricular conduction (HP:0005150)1.89966881
105Abnormal gallbladder morphology (HP:0012437)1.89438708
106Spontaneous abortion (HP:0005268)1.88694468
107Foot dorsiflexor weakness (HP:0009027)1.88642071
108Abnormality of the calf musculature (HP:0001430)1.88165686
109Joint laxity (HP:0001388)1.87576713
110Blue sclerae (HP:0000592)1.87496174
111Abnormal delivery (HP:0001787)1.85827844
112Exercise-induced muscle cramps (HP:0003710)1.85617451
113Lower limb amyotrophy (HP:0007210)1.85143176
114Hip contracture (HP:0003273)1.84454706
115Ulnar deviation of the wrist (HP:0003049)1.84316135
116Lymphangioma (HP:0100764)1.83482904
117Stridor (HP:0010307)1.83436179
118Sudden death (HP:0001699)1.83235559
119Osteolytic defects of the phalanges of the hand (HP:0009771)1.82736192
120Osteolytic defects of the hand bones (HP:0009699)1.82736192
121Generalized amyotrophy (HP:0003700)1.82715594
122Scapular winging (HP:0003691)1.82246807
123Upper limb amyotrophy (HP:0009129)1.82222060
124Distal upper limb amyotrophy (HP:0007149)1.82222060
125Cerebral inclusion bodies (HP:0100314)1.80078648
126Hemorrhage of the eye (HP:0011885)1.78874668
127Spondylolisthesis (HP:0003302)1.78358672
128Hyperacusis (HP:0010780)1.78212388
129Abnormality of the foot musculature (HP:0001436)1.77834614
130Slender build (HP:0001533)1.77098556
131Supranuclear gaze palsy (HP:0000605)1.76987049
132Wrist flexion contracture (HP:0001239)1.76520948
133Camptodactyly of toe (HP:0001836)1.75496046
134Calcaneovalgus deformity (HP:0001848)1.75468743
135Abnormal cartilage morphology (HP:0002763)1.74822977
136Ankle clonus (HP:0011448)1.74218280
137Follicular hyperkeratosis (HP:0007502)1.73995141
138Aneurysm (HP:0002617)1.73852299
139Limb-girdle muscle weakness (HP:0003325)1.73753595
140Axonal loss (HP:0003447)1.73727732
141Heart block (HP:0012722)1.73066326
142Vascular calcification (HP:0004934)1.72998029
143Pulmonary artery stenosis (HP:0004415)1.72896559
144Lipoatrophy (HP:0100578)1.70574046
145Dilatation of the ascending aorta (HP:0005111)1.69972814
146Wide anterior fontanel (HP:0000260)1.68809424
147Soft skin (HP:0000977)1.68195742
148Overgrowth (HP:0001548)1.66815631
149Biconcave vertebral bodies (HP:0004586)1.66463544
150Torticollis (HP:0000473)1.65597990
151Hyperbilirubinemia (HP:0002904)1.65558591
152Abnormality of proline metabolism (HP:0010907)1.64920331
153Hydroxyprolinuria (HP:0003080)1.64920331
154Muscle fiber splitting (HP:0003555)1.64604050
155Striae distensae (HP:0001065)1.64525177
156Neonatal onset (HP:0003623)1.63890568
157Hyperextensible skin (HP:0000974)1.61458783
158Action tremor (HP:0002345)1.60060298

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.18298654
2SIK13.79313807
3MYLK2.71962137
4BCKDK2.62742493
5PDGFRA2.54155908
6MARK12.54110119
7PKN22.47182159
8ERN12.46947566
9TTN2.31709789
10DDR22.23921531
11NTRK32.04212420
12EPHB11.93255628
13FGFR41.92728476
14CAMK1D1.92483149
15RIPK11.89245912
16LATS11.83984593
17FGFR21.79643432
18CAMK1G1.76482379
19PHKG21.72428680
20PHKG11.72428680
21PRPF4B1.65628783
22LATS21.53253561
23DMPK1.50581047
24UHMK11.46291042
25PTK61.45732152
26BMX1.44739499
27PRKD31.40767834
28PAK61.40435156
29LMTK21.35961134
30TESK11.34345838
31NTRK11.34242372
32LIMK11.33222755
33ERBB41.27587252
34MAP2K41.22973702
35ARAF1.18028306
36MAP3K71.15484633
37MET1.15161865
38PAK31.13643310
39RET1.09654472
40TYRO31.09232234
41CAMKK11.08893589
42CAMK11.08658293
43GRK51.08148658
44PIK3CA1.06440129
45PRKCH1.05893460
46CAMK2B1.04946080
47ICK1.03517310
48PDGFRB0.99711390
49PRKD10.99394525
50CDC42BPA0.99117543
51EPHA30.98193580
52PAK20.97926423
53KSR20.94974678
54EEF2K0.93358713
55PTK20.93285003
56TGFBR20.91898488
57DAPK20.90209852
58FER0.86186519
59PRKAA20.86175917
60EPHA40.85898803
61PIK3CG0.85061946
62WNK10.84288400
63PINK10.84255312
64ROCK20.84025186
65NEK90.82444870
66ROCK10.81830664
67OBSCN0.81682075
68FGFR10.81471721
69MAPK120.80785474
70PKN10.79278475
71EPHB20.78501348
72MOS0.76355769
73SGK30.76212926
74MAPK110.75325822
75PTK2B0.73894236
76AKT30.73876949
77STK380.73487812
78MTOR0.73456845
79JAK10.70008573
80CDK50.69722507
81SGK20.69283859
82TIE10.68862965
83CAMK2G0.68739001
84SGK2230.68706028
85SGK4940.68706028
86PDPK10.66991328
87GSK3A0.66677473
88MAPK40.66650261
89ERBB20.66334133
90RPS6KA20.66177458
91MAP3K60.65701794
92ILK0.63250792
93MAP3K130.61254849
94MINK10.60843522
95LRRK20.60252456
96MAPK100.59558820
97MAP2K10.59423644
98DYRK1B0.56785439
99CAMK2A0.55811163
100CDK60.55196290
101MST1R0.54961984
102PDK40.54622813
103PDK30.54622813
104INSRR0.53662930
105MAPKAPK50.53586846
106FGFR30.53192763
107ABL20.52774358
108STK390.52662827
109MAP3K100.52192631
110NTRK20.50346150
111CDK150.49709134
112MAPK70.49085636
113PRKCZ0.48115304
114PRKG20.47963129
115PRKAA10.46565804
116PRKACG0.46227526
117TAOK10.45717617
118JAK20.45061231
119TRPM70.44542802
120CDK11A0.44044230
121PRKG10.43778266
122MAPKAPK30.43737644
123CAMK40.43670819
124MARK20.43277027
125CDK180.43222319
126PLK20.43070047
127DAPK30.42580029
128SRC0.41756655
129PRKD20.40225732
130CAMK2D0.39130583
131PDK10.37748680

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009105.18271353
2Primary bile acid biosynthesis_Homo sapiens_hsa001203.59830154
3Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.84548932
4Arginine biosynthesis_Homo sapiens_hsa002202.83860936
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.77957685
6Fatty acid degradation_Homo sapiens_hsa000712.45151129
7Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.40567914
8Complement and coagulation cascades_Homo sapiens_hsa046102.35113518
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.27467664
10Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.27338936
11Fatty acid metabolism_Homo sapiens_hsa012122.15908545
12PPAR signaling pathway_Homo sapiens_hsa033202.12650750
13Tryptophan metabolism_Homo sapiens_hsa003802.11626399
14Butanoate metabolism_Homo sapiens_hsa006502.07517110
15Propanoate metabolism_Homo sapiens_hsa006402.07338332
16Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.95593183
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.75490801
18Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.68875706
19Long-term potentiation_Homo sapiens_hsa047201.64007305
20Bile secretion_Homo sapiens_hsa049761.58730172
21Circadian entrainment_Homo sapiens_hsa047131.51330408
22Peroxisome_Homo sapiens_hsa041461.50942051
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.50630601
24Insulin secretion_Homo sapiens_hsa049111.42354207
25Caffeine metabolism_Homo sapiens_hsa002321.42144642
26cGMP-PKG signaling pathway_Homo sapiens_hsa040221.41567543
27Staphylococcus aureus infection_Homo sapiens_hsa051501.40361213
28Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.40042900
29Fatty acid elongation_Homo sapiens_hsa000621.38884325
30Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.38738177
31beta-Alanine metabolism_Homo sapiens_hsa004101.37310535
32Pentose and glucuronate interconversions_Homo sapiens_hsa000401.32705757
33Vascular smooth muscle contraction_Homo sapiens_hsa042701.31943277
34Chemical carcinogenesis_Homo sapiens_hsa052041.30820358
35Amphetamine addiction_Homo sapiens_hsa050311.30771383
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.29488046
37Fatty acid biosynthesis_Homo sapiens_hsa000611.28066079
38Glutamatergic synapse_Homo sapiens_hsa047241.27605052
39Histidine metabolism_Homo sapiens_hsa003401.24886597
40Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.24775359
41Oxytocin signaling pathway_Homo sapiens_hsa049211.24706836
42Cocaine addiction_Homo sapiens_hsa050301.21111137
43Synaptic vesicle cycle_Homo sapiens_hsa047211.18907564
44Pyruvate metabolism_Homo sapiens_hsa006201.16995144
45Gap junction_Homo sapiens_hsa045401.16220886
46Estrogen signaling pathway_Homo sapiens_hsa049151.14473191
47cAMP signaling pathway_Homo sapiens_hsa040241.14301770
48Melanogenesis_Homo sapiens_hsa049161.13292720
49GnRH signaling pathway_Homo sapiens_hsa049121.12597721
50Calcium signaling pathway_Homo sapiens_hsa040201.10708890
51Morphine addiction_Homo sapiens_hsa050321.10250921
52Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.07767530
53Starch and sucrose metabolism_Homo sapiens_hsa005001.07244665
54Retinol metabolism_Homo sapiens_hsa008301.06454132
55Carbon metabolism_Homo sapiens_hsa012001.04556956
56Salivary secretion_Homo sapiens_hsa049701.04478076
57Phenylalanine metabolism_Homo sapiens_hsa003601.01720326
58Cholinergic synapse_Homo sapiens_hsa047251.01462106
59Steroid biosynthesis_Homo sapiens_hsa001001.01256523
60Dopaminergic synapse_Homo sapiens_hsa047280.98758120
61Biosynthesis of amino acids_Homo sapiens_hsa012300.98623424
62AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.97902819
63Sulfur metabolism_Homo sapiens_hsa009200.93829677
64Tyrosine metabolism_Homo sapiens_hsa003500.92411896
65Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.91337593
66Lysine degradation_Homo sapiens_hsa003100.90067657
67Thyroid hormone signaling pathway_Homo sapiens_hsa049190.89986929
68Regulation of actin cytoskeleton_Homo sapiens_hsa048100.87973259
69Axon guidance_Homo sapiens_hsa043600.86394793
70Glycosaminoglycan degradation_Homo sapiens_hsa005310.85329096
71Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.84381605
72Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84376347
73Rap1 signaling pathway_Homo sapiens_hsa040150.83908724
74Fat digestion and absorption_Homo sapiens_hsa049750.83887106
75Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.83853985
76ABC transporters_Homo sapiens_hsa020100.83025427
77Vitamin B6 metabolism_Homo sapiens_hsa007500.81645376
78Nicotine addiction_Homo sapiens_hsa050330.81632210
79Adherens junction_Homo sapiens_hsa045200.81597124
80Arginine and proline metabolism_Homo sapiens_hsa003300.81495770
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.80258899
82Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.76696576
83Circadian rhythm_Homo sapiens_hsa047100.74678733
84Drug metabolism - other enzymes_Homo sapiens_hsa009830.73653825
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.73105321
86Tight junction_Homo sapiens_hsa045300.72225514
87Selenocompound metabolism_Homo sapiens_hsa004500.71755489
88Cardiac muscle contraction_Homo sapiens_hsa042600.69270262
89PI3K-Akt signaling pathway_Homo sapiens_hsa041510.69058732
90Glycerolipid metabolism_Homo sapiens_hsa005610.68351012
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66777214
92Cysteine and methionine metabolism_Homo sapiens_hsa002700.66545626
93Hippo signaling pathway_Homo sapiens_hsa043900.66044467
94ECM-receptor interaction_Homo sapiens_hsa045120.65514547
95Ras signaling pathway_Homo sapiens_hsa040140.65196298
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.65031406
97VEGF signaling pathway_Homo sapiens_hsa043700.64937912
98Prion diseases_Homo sapiens_hsa050200.64932578
99MAPK signaling pathway_Homo sapiens_hsa040100.64912276
100ErbB signaling pathway_Homo sapiens_hsa040120.64395667
101Melanoma_Homo sapiens_hsa052180.63896656
102Pancreatic secretion_Homo sapiens_hsa049720.62238236
103Notch signaling pathway_Homo sapiens_hsa043300.60940542
104Chronic myeloid leukemia_Homo sapiens_hsa052200.60073355
105Renal cell carcinoma_Homo sapiens_hsa052110.59721998
106Long-term depression_Homo sapiens_hsa047300.59721018
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.59649809
108Insulin resistance_Homo sapiens_hsa049310.57658369
109Choline metabolism in cancer_Homo sapiens_hsa052310.57310890
110Endocytosis_Homo sapiens_hsa041440.57013200
111Phosphatidylinositol signaling system_Homo sapiens_hsa040700.55429426
112Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.54804089
113mTOR signaling pathway_Homo sapiens_hsa041500.54345411
114Endometrial cancer_Homo sapiens_hsa052130.53543952
115Wnt signaling pathway_Homo sapiens_hsa043100.53030457
116Dilated cardiomyopathy_Homo sapiens_hsa054140.52874823
117Focal adhesion_Homo sapiens_hsa045100.49672951
118Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.48955243
119AMPK signaling pathway_Homo sapiens_hsa041520.44893272
120Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42136187
121Glucagon signaling pathway_Homo sapiens_hsa049220.41492204
122Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.39672191
123Amoebiasis_Homo sapiens_hsa051460.38088161
124Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.37532250
125Sulfur relay system_Homo sapiens_hsa041220.37091364
126Proteoglycans in cancer_Homo sapiens_hsa052050.32598893
127Vitamin digestion and absorption_Homo sapiens_hsa049770.30800134
128Insulin signaling pathway_Homo sapiens_hsa049100.30727060
129Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.27019860
130Glioma_Homo sapiens_hsa052140.25897091
131Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.24386392
132Ovarian steroidogenesis_Homo sapiens_hsa049130.23903315
133Protein digestion and absorption_Homo sapiens_hsa049740.23614613
134Folate biosynthesis_Homo sapiens_hsa007900.23253148
135Cyanoamino acid metabolism_Homo sapiens_hsa004600.23024457
136Central carbon metabolism in cancer_Homo sapiens_hsa052300.22354612
137GABAergic synapse_Homo sapiens_hsa047270.21530355
138Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.20163010
139Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.20067539
140Longevity regulating pathway - mammal_Homo sapiens_hsa042110.20007808
141Aldosterone synthesis and secretion_Homo sapiens_hsa049250.19416760
142Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.17205401
143Bladder cancer_Homo sapiens_hsa052190.16259158
144Glycerophospholipid metabolism_Homo sapiens_hsa005640.15134625
145Dorso-ventral axis formation_Homo sapiens_hsa043200.14837410
146Pentose phosphate pathway_Homo sapiens_hsa000300.14604912
147Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.13923677
148Thyroid hormone synthesis_Homo sapiens_hsa049180.13737158
149Renin secretion_Homo sapiens_hsa049240.13675918
150Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.13393216
151Phospholipase D signaling pathway_Homo sapiens_hsa040720.13144813
152Gastric acid secretion_Homo sapiens_hsa049710.12854393
153Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.12611738
154Type II diabetes mellitus_Homo sapiens_hsa049300.11896938

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »