ZDHHC14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)4.92068479
2axon ensheathment in central nervous system (GO:0032291)4.92068479
3locomotory exploration behavior (GO:0035641)4.53010752
4neuron cell-cell adhesion (GO:0007158)4.49425950
5synaptic vesicle docking involved in exocytosis (GO:0016081)4.43351951
6ionotropic glutamate receptor signaling pathway (GO:0035235)4.41335370
7regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.24493708
8nerve growth factor signaling pathway (GO:0038180)4.12785245
9glutamate receptor signaling pathway (GO:0007215)4.12490014
10neuronal action potential propagation (GO:0019227)4.12183821
11alanine transport (GO:0032328)4.03468259
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.00879570
13C4-dicarboxylate transport (GO:0015740)3.97598518
14regulation of short-term neuronal synaptic plasticity (GO:0048172)3.94363602
15regulation of memory T cell differentiation (GO:0043380)3.88406556
16L-amino acid import (GO:0043092)3.78000933
17protein localization to synapse (GO:0035418)3.73530730
18synaptic vesicle exocytosis (GO:0016079)3.72380707
19transmission of nerve impulse (GO:0019226)3.71996553
20synaptic vesicle maturation (GO:0016188)3.70236450
21adult walking behavior (GO:0007628)3.68059619
22vocalization behavior (GO:0071625)3.54842437
23response to methylmercury (GO:0051597)3.54811382
24regulation of glutamate receptor signaling pathway (GO:1900449)3.54770474
25G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.54532770
26presynaptic membrane assembly (GO:0097105)3.53435484
27potassium ion homeostasis (GO:0055075)3.52423688
28myelination (GO:0042552)3.51731102
29regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.50878505
30synaptic transmission, glutamatergic (GO:0035249)3.50242169
31presynaptic membrane organization (GO:0097090)3.50173295
32ensheathment of neurons (GO:0007272)3.48781686
33axon ensheathment (GO:0008366)3.48781686
34neuron recognition (GO:0008038)3.47602724
35positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.46370178
36potassium ion import (GO:0010107)3.44575392
37regulation of activation of Janus kinase activity (GO:0010533)3.42809320
38regulation of excitatory postsynaptic membrane potential (GO:0060079)3.38672330
39gamma-aminobutyric acid signaling pathway (GO:0007214)3.38397367
40regulation of long-term neuronal synaptic plasticity (GO:0048169)3.29727920
41auditory receptor cell stereocilium organization (GO:0060088)3.29113532
42regulation of dendritic spine morphogenesis (GO:0061001)3.28561027
43serotonin metabolic process (GO:0042428)3.28484723
44behavioral response to nicotine (GO:0035095)3.28123359
45neuron-neuron synaptic transmission (GO:0007270)3.25863377
46regulation of neuronal synaptic plasticity (GO:0048168)3.25493900
47neuromuscular process controlling posture (GO:0050884)3.25166786
48proline transport (GO:0015824)3.24988201
49axonal fasciculation (GO:0007413)3.21243299
50positive regulation of synapse maturation (GO:0090129)3.19984277
51regulation of postsynaptic membrane potential (GO:0060078)3.15246392
52negative regulation of neurotransmitter transport (GO:0051589)3.14979248
53primary amino compound metabolic process (GO:1901160)3.13246045
54exploration behavior (GO:0035640)3.12753883
55long-chain fatty acid biosynthetic process (GO:0042759)3.11751929
56glutamate secretion (GO:0014047)3.11579291
57amino acid import (GO:0043090)3.11458879
58regulation of synaptic vesicle exocytosis (GO:2000300)3.10538211
59cell differentiation in hindbrain (GO:0021533)3.08151046
60dendritic spine morphogenesis (GO:0060997)3.07573070
61long-term memory (GO:0007616)3.06324298
62chemosensory behavior (GO:0007635)3.03879981
63membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.02089436
64gamma-aminobutyric acid transport (GO:0015812)3.02046770
65fucose catabolic process (GO:0019317)3.00673509
66L-fucose metabolic process (GO:0042354)3.00673509
67L-fucose catabolic process (GO:0042355)3.00673509
68regulation of glutamate secretion (GO:0014048)3.00052572
69dendrite morphogenesis (GO:0048813)2.96694905
70neuromuscular synaptic transmission (GO:0007274)2.96070829
71negative regulation of synaptic transmission, GABAergic (GO:0032229)2.94931427
72positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.94495472
73membrane depolarization (GO:0051899)2.93537757
74regulation of dendritic spine development (GO:0060998)2.92493370
75positive regulation of dendritic spine morphogenesis (GO:0061003)2.92463562
76negative regulation of amino acid transport (GO:0051956)2.91023655
77negative regulation of cytosolic calcium ion concentration (GO:0051481)2.90120102
78cellular sodium ion homeostasis (GO:0006883)2.90035134
79adenosine receptor signaling pathway (GO:0001973)2.89577569
80sodium ion export (GO:0071436)2.89044041
81regulation of synaptic transmission, glutamatergic (GO:0051966)2.88438145
82postsynaptic membrane organization (GO:0001941)2.87274374
83regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.86724506
84cellular potassium ion homeostasis (GO:0030007)2.85963247
85neuron remodeling (GO:0016322)2.85050475
86neuromuscular process controlling balance (GO:0050885)2.84711924
87regulation of voltage-gated calcium channel activity (GO:1901385)2.84390936
88cerebellar Purkinje cell layer development (GO:0021680)2.84373687
89multicellular organismal movement (GO:0050879)2.83691196
90musculoskeletal movement (GO:0050881)2.83691196
91regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.83671266
92positive regulation of dendritic spine development (GO:0060999)2.82074713
93cellular response to nerve growth factor stimulus (GO:1990090)2.82067022
94response to nerve growth factor (GO:1990089)2.82067022
95regulation of synaptic plasticity (GO:0048167)2.81644739
96cerebellar granule cell differentiation (GO:0021707)2.81588959
97cerebellar Purkinje cell differentiation (GO:0021702)2.81212233
98cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.79945065
99membrane depolarization during action potential (GO:0086010)2.79143452
100myelin maintenance (GO:0043217)2.78427080
101regulation of synapse maturation (GO:0090128)2.78283671
102regulation of synaptic vesicle transport (GO:1902803)2.77755474
103erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.77317734
104L-phenylalanine catabolic process (GO:0006559)2.77317734
105cellular potassium ion transport (GO:0071804)2.77195429
106potassium ion transmembrane transport (GO:0071805)2.77195429
107positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.76743031
108positive regulation of cell fate commitment (GO:0010455)2.76573020
109fatty acid elongation (GO:0030497)2.76509711
110negative regulation of neurotransmitter secretion (GO:0046929)2.75696188
111opioid receptor signaling pathway (GO:0038003)2.75624259
112regulation of synapse structural plasticity (GO:0051823)2.75124742
113regulation of neurotransmitter levels (GO:0001505)2.74253213
114neurotransmitter secretion (GO:0007269)2.74118686
115negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.73525709
116positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.72727163
117membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.72179509
118acidic amino acid transport (GO:0015800)2.72051651
119detection of calcium ion (GO:0005513)2.71471052
120nephron epithelium morphogenesis (GO:0072088)2.69852497
121nephron tubule morphogenesis (GO:0072078)2.69852497
122neurofilament cytoskeleton organization (GO:0060052)2.69824638
123negative regulation of protein localization to cell surface (GO:2000009)2.69624806
124positive regulation of membrane potential (GO:0045838)2.67194627
125cellular ketone body metabolic process (GO:0046950)2.67158972
126synaptic vesicle endocytosis (GO:0048488)2.66888415
127glycine transport (GO:0015816)2.66413662
128mating behavior (GO:0007617)2.65664954
129regulation of calcium ion-dependent exocytosis (GO:0017158)2.65253687
130neuronal ion channel clustering (GO:0045161)2.65157728
131regulation of vesicle fusion (GO:0031338)2.65046396
132long-term synaptic potentiation (GO:0060291)2.64444228
133learning (GO:0007612)2.64318022
134regulation of neurotransmitter transport (GO:0051588)2.63653242
135neurotransmitter-gated ion channel clustering (GO:0072578)2.63442236
136regulation of neurotransmitter secretion (GO:0046928)2.63295422
137positive regulation of neurotransmitter transport (GO:0051590)2.62580601
138positive regulation of synapse assembly (GO:0051965)2.62387874
139potassium ion transport (GO:0006813)2.60256069
140negative regulation of peptidyl-threonine phosphorylation (GO:0010801)2.58100333
141membrane hyperpolarization (GO:0060081)2.57817233
142adult locomotory behavior (GO:0008344)2.57407269
143nucleoside transmembrane transport (GO:1901642)2.56965221
144membrane repolarization (GO:0086009)2.56150216
145renal tubule morphogenesis (GO:0061333)2.55872562
146L-glutamate transport (GO:0015813)2.53199988
147activated T cell proliferation (GO:0050798)2.52518558
148neurotransmitter transport (GO:0006836)2.51450681
149inositol phosphate-mediated signaling (GO:0048016)2.50980537
150negative regulation of axonogenesis (GO:0050771)2.50787696
151regulation of sensory perception (GO:0051931)2.50237249
152startle response (GO:0001964)2.48950942
153vesicle transport along microtubule (GO:0047496)2.46948660
154detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.45436315
155detection of temperature stimulus involved in sensory perception (GO:0050961)2.45436315
156positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.45218878
157regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.43908893
158regulation of collateral sprouting (GO:0048670)2.43542678

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.86704874
2GBX2_23144817_ChIP-Seq_PC3_Human3.56742635
3* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.84755249
4* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.82919366
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.71462986
6* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.42254287
7* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.40885844
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.40885844
9* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.38604437
10SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.31674228
11* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.28635015
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.22865615
13RARB_27405468_Chip-Seq_BRAIN_Mouse2.18869883
14GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.17767893
15* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.17458594
16DROSHA_22980978_ChIP-Seq_HELA_Human2.15977066
17IKZF1_21737484_ChIP-ChIP_HCT116_Human2.09207886
18* EZH2_27294783_Chip-Seq_ESCs_Mouse2.08492501
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.07109274
20AR_21572438_ChIP-Seq_LNCaP_Human2.06387531
21TAF15_26573619_Chip-Seq_HEK293_Human2.03529009
22VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.01007717
23SUZ12_27294783_Chip-Seq_ESCs_Mouse2.00297028
24EZH2_27304074_Chip-Seq_ESCs_Mouse2.00144696
25REST_21632747_ChIP-Seq_MESCs_Mouse1.98177909
26* RNF2_27304074_Chip-Seq_ESCs_Mouse1.90834814
27FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.80019981
28* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.77919320
29ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70942644
30IGF1R_20145208_ChIP-Seq_DFB_Human1.58228339
31* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.55829331
32* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.55222008
33SMAD4_21799915_ChIP-Seq_A2780_Human1.51304072
34PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.50236025
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.49690145
36REST_18959480_ChIP-ChIP_MESCs_Mouse1.46413857
37BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.45883096
38OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.45729231
39RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.44800899
40PIAS1_25552417_ChIP-Seq_VCAP_Human1.42774664
41RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.42611033
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.40867577
43MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.40324986
44TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.40193663
45SMAD3_21741376_ChIP-Seq_EPCs_Human1.37965313
46SMAD_19615063_ChIP-ChIP_OVARY_Human1.35918996
47TP53_16413492_ChIP-PET_HCT116_Human1.35812528
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34850602
49P300_19829295_ChIP-Seq_ESCs_Human1.34061687
50CDX2_19796622_ChIP-Seq_MESCs_Mouse1.32173860
51CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30053734
52ER_23166858_ChIP-Seq_MCF-7_Human1.29357093
53GATA1_22025678_ChIP-Seq_K562_Human1.29307938
54NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.28451798
55* STAT3_23295773_ChIP-Seq_U87_Human1.27947595
56* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25116571
57RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.24767932
58POU3F2_20337985_ChIP-ChIP_501MEL_Human1.23444563
59NR3C1_23031785_ChIP-Seq_PC12_Mouse1.22669656
60ZNF217_24962896_ChIP-Seq_MCF-7_Human1.21154082
61BCAT_22108803_ChIP-Seq_LS180_Human1.20824829
62* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.18536420
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.18160459
64BMI1_23680149_ChIP-Seq_NPCS_Mouse1.15980935
65NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.15160975
66* SOX2_21211035_ChIP-Seq_LN229_Gbm1.15078023
67CBX2_27304074_Chip-Seq_ESCs_Mouse1.13675901
68AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13465876
69* TCF4_23295773_ChIP-Seq_U87_Human1.12130299
70P53_22127205_ChIP-Seq_FIBROBLAST_Human1.10504950
71TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09662919
72AR_25329375_ChIP-Seq_VCAP_Human1.09179158
73ARNT_22903824_ChIP-Seq_MCF-7_Human1.07789641
74CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.07304265
75VDR_22108803_ChIP-Seq_LS180_Human1.06907825
76AHR_22903824_ChIP-Seq_MCF-7_Human1.06517605
77ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.05499473
78TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04828206
79POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04828206
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04336304
81HTT_18923047_ChIP-ChIP_STHdh_Human1.03892924
82PRDM14_20953172_ChIP-Seq_ESCs_Human1.03507603
83* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02951148
84RING1B_27294783_Chip-Seq_ESCs_Mouse1.01034839
85ERG_21242973_ChIP-ChIP_JURKAT_Human1.00783111
86ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.99820536
87ZNF274_21170338_ChIP-Seq_K562_Hela0.99614719
88TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99162139
89* AR_19668381_ChIP-Seq_PC3_Human0.98859378
90RUNX2_22187159_ChIP-Seq_PCA_Human0.97073399
91SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96736492
92ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.96667669
93NR3C1_21868756_ChIP-Seq_MCF10A_Human0.95285048
94TP53_18474530_ChIP-ChIP_U2OS_Human0.93808689
95DNAJC2_21179169_ChIP-ChIP_NT2_Human0.93592839
96SMAD3_21741376_ChIP-Seq_HESCs_Human0.93304862
97ETV2_25802403_ChIP-Seq_MESCs_Mouse0.93256817
98* TAF2_19829295_ChIP-Seq_ESCs_Human0.91723314
99TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.91244800
100TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.90580041
101SMAD4_21741376_ChIP-Seq_HESCs_Human0.89503952
102MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.89471669
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89273073
104ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.88775541
105YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88568975
106CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.88541604
107FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.88440349
108* RNF2_27304074_Chip-Seq_NSC_Mouse0.88379346
109RING1B_27294783_Chip-Seq_NPCs_Mouse0.88366658
110* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88123365
111PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.88112187
112GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.87574196
113NANOG_18555785_Chip-Seq_ESCs_Mouse0.86921161
114EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.86797490
115SMAD4_21741376_ChIP-Seq_EPCs_Human0.86122081
116KDM2B_26808549_Chip-Seq_REH_Human0.85465439
117EP300_21415370_ChIP-Seq_HL-1_Mouse0.84760895
118* SMAD3_21741376_ChIP-Seq_ESCs_Human0.83793312
119WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.83631963
120TCF4_22108803_ChIP-Seq_LS180_Human0.81795490

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.61630596
2MP0003880_abnormal_central_pattern4.67714169
3MP0003635_abnormal_synaptic_transmissio3.55915312
4MP0004270_analgesia3.35069093
5MP0009745_abnormal_behavioral_response3.19393309
6MP0000920_abnormal_myelination3.12242676
7MP0002064_seizures3.10425357
8MP0003195_calcinosis2.91702663
9MP0009046_muscle_twitch2.86581012
10MP0002063_abnormal_learning/memory/cond2.76400293
11MP0002272_abnormal_nervous_system2.76097435
12MP0003690_abnormal_glial_cell2.64665511
13MP0005423_abnormal_somatic_nervous2.58465885
14MP0002735_abnormal_chemical_nociception2.56462894
15MP0001486_abnormal_startle_reflex2.54029615
16MP0001968_abnormal_touch/_nociception2.53831580
17MP0002822_catalepsy2.47627309
18MP0002572_abnormal_emotion/affect_behav2.47300281
19MP0010386_abnormal_urinary_bladder2.39766156
20MP0002734_abnormal_mechanical_nocicepti2.26468779
21MP0003283_abnormal_digestive_organ2.25047776
22MP0001440_abnormal_grooming_behavior2.12790787
23MP0002736_abnormal_nociception_after2.11400449
24MP0005171_absent_coat_pigmentation2.08749091
25MP0003329_amyloid_beta_deposits2.05071384
26MP0008875_abnormal_xenobiotic_pharmacok2.03555599
27MP0000778_abnormal_nervous_system1.95862357
28MP0001970_abnormal_pain_threshold1.95174281
29MP0004742_abnormal_vestibular_system1.92320782
30MP0002067_abnormal_sensory_capabilities1.90054344
31MP0002837_dystrophic_cardiac_calcinosis1.88855027
32MP0008569_lethality_at_weaning1.86314913
33MP0002139_abnormal_hepatobiliary_system1.84532537
34MP0005409_darkened_coat_color1.78584125
35MP0002733_abnormal_thermal_nociception1.77736363
36MP0001501_abnormal_sleep_pattern1.72801377
37MP0001529_abnormal_vocalization1.72254977
38MP0003172_abnormal_lysosome_physiology1.71912145
39MP0004142_abnormal_muscle_tone1.62432589
40MP0004147_increased_porphyrin_level1.58954786
41MP0004885_abnormal_endolymph1.58009554
42MP0003634_abnormal_glial_cell1.57291526
43MP0004145_abnormal_muscle_electrophysio1.56657868
44MP0000955_abnormal_spinal_cord1.54546897
45MP0002229_neurodegeneration1.52704639
46MP0003633_abnormal_nervous_system1.49384001
47MP0001905_abnormal_dopamine_level1.48562802
48MP0003632_abnormal_nervous_system1.48505173
49MP0002184_abnormal_innervation1.46715790
50MP0003631_nervous_system_phenotype1.44934378
51MP0000604_amyloidosis1.44542279
52MP0002638_abnormal_pupillary_reflex1.43668255
53MP0002882_abnormal_neuron_morphology1.41902367
54MP0002066_abnormal_motor_capabilities/c1.40613645
55MP0005085_abnormal_gallbladder_physiolo1.40540539
56MP0005360_urolithiasis1.39062360
57MP0005645_abnormal_hypothalamus_physiol1.38796208
58MP0004924_abnormal_behavior1.37977458
59MP0005386_behavior/neurological_phenoty1.37977458
60MP0002557_abnormal_social/conspecific_i1.36800515
61MP0010329_abnormal_lipoprotein_level1.35798306
62MP0005332_abnormal_amino_acid1.35489766
63MP0004811_abnormal_neuron_physiology1.22261104
64MP0009780_abnormal_chondrocyte_physiolo1.20830971
65MP0005058_abnormal_lysosome_morphology1.18514291
66MP0002138_abnormal_hepatobiliary_system1.16555826
67MP0001485_abnormal_pinna_reflex1.15944612
68MP0003252_abnormal_bile_duct1.15828103
69MP0002090_abnormal_vision1.13940407
70MP0005646_abnormal_pituitary_gland1.12717179
71MP0001944_abnormal_pancreas_morphology1.10302886
72MP0003656_abnormal_erythrocyte_physiolo1.08945060
73MP0005379_endocrine/exocrine_gland_phen1.08795178
74MP0000566_synostosis1.08631851
75MP0006072_abnormal_retinal_apoptosis1.08184889
76MP0005551_abnormal_eye_electrophysiolog1.07793065
77MP0003075_altered_response_to1.03297713
78MP0001963_abnormal_hearing_physiology1.00535056
79MP0003950_abnormal_plasma_membrane1.00194559
80MP0004215_abnormal_myocardial_fiber0.98538873
81MP0002152_abnormal_brain_morphology0.97462685
82MP0001502_abnormal_circadian_rhythm0.96609955
83MP0001986_abnormal_taste_sensitivity0.95020085
84MP0001756_abnormal_urination0.93650478
85MP0004019_abnormal_vitamin_homeostasis0.93443416
86MP0005377_hearing/vestibular/ear_phenot0.93153232
87MP0003878_abnormal_ear_physiology0.93153232
88MP0001984_abnormal_olfaction0.91352680
89MP0005410_abnormal_fertilization0.91291086
90MP0005636_abnormal_mineral_homeostasis0.90633141
91MP0008874_decreased_physiological_sensi0.89487230
92MP0003879_abnormal_hair_cell0.87460031
93MP0002909_abnormal_adrenal_gland0.87368776
94MP0006276_abnormal_autonomic_nervous0.87271544
95MP0006082_CNS_inflammation0.86927618
96MP0001765_abnormal_ion_homeostasis0.86658887
97MP0005365_abnormal_bile_salt0.86454485
98MP0001299_abnormal_eye_distance/0.85720716
99MP0000631_abnormal_neuroendocrine_gland0.85691803
100MP0002752_abnormal_somatic_nervous0.84477507
101MP0003045_fibrosis0.83415496
102MP0004510_myositis0.82844758
103MP0004133_heterotaxia0.82730627
104MP0003787_abnormal_imprinting0.82388248
105MP0008260_abnormal_autophagy0.82182631
106MP0003191_abnormal_cellular_cholesterol0.82158504
107MP0000569_abnormal_digit_pigmentation0.79985436
108MP0002693_abnormal_pancreas_physiology0.79485690
109MP0000026_abnormal_inner_ear0.79297019
110MP0005220_abnormal_exocrine_pancreas0.77985308
111MP0000015_abnormal_ear_pigmentation0.77056865
112MP0000013_abnormal_adipose_tissue0.75777384
113MP0004858_abnormal_nervous_system0.75661950
114MP0005448_abnormal_energy_balance0.73953685
115MP0002069_abnormal_eating/drinking_beha0.73867491
116MP0001177_atelectasis0.72455149
117MP0008872_abnormal_physiological_respon0.71401035
118MP0005253_abnormal_eye_physiology0.71345859
119MP0002876_abnormal_thyroid_physiology0.71315850
120MP0000230_abnormal_systemic_arterial0.69513502
121MP0003011_delayed_dark_adaptation0.68775219
122MP0005535_abnormal_body_temperature0.68139561
123MP0001664_abnormal_digestion0.67550333
124MP0001188_hyperpigmentation0.67040819
125MP0005167_abnormal_blood-brain_barrier0.66246525
126MP0000747_muscle_weakness0.65711560
127MP0004085_abnormal_heartbeat0.65545431
128MP0005310_abnormal_salivary_gland0.63319412
129MP0004043_abnormal_pH_regulation0.62546182
130MP0001851_eye_inflammation0.61440461
131MP0003183_abnormal_peptide_metabolism0.60630170
132MP0003136_yellow_coat_color0.58588228
133MP0003137_abnormal_impulse_conducting0.55862837
134MP0003303_peritoneal_inflammation0.55466914
135MP0004185_abnormal_adipocyte_glucose0.54808238
136MP0002295_abnormal_pulmonary_circulatio0.53174564

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.28237666
2Myokymia (HP:0002411)6.08058653
3Neurofibrillary tangles (HP:0002185)5.04327474
4Supranuclear gaze palsy (HP:0000605)4.71661304
5Focal seizures (HP:0007359)4.48259539
6Dysmetria (HP:0001310)4.16391007
7Cerebral inclusion bodies (HP:0100314)4.11822796
8Degeneration of the lateral corticospinal tracts (HP:0002314)4.09931449
9Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)4.09931449
10Atonic seizures (HP:0010819)3.93342702
11Dysdiadochokinesis (HP:0002075)3.63089364
12Epileptic encephalopathy (HP:0200134)3.58864204
13Abnormality of the corticospinal tract (HP:0002492)3.58382054
14Progressive cerebellar ataxia (HP:0002073)3.55519974
15Visual hallucinations (HP:0002367)3.53815387
16Peripheral hypomyelination (HP:0007182)3.42102403
17Scanning speech (HP:0002168)3.37470736
18Gaze-evoked nystagmus (HP:0000640)3.34341302
19Action tremor (HP:0002345)3.30970969
20Broad-based gait (HP:0002136)3.27415089
21Intention tremor (HP:0002080)3.25180030
22Febrile seizures (HP:0002373)3.18059894
23Dialeptic seizures (HP:0011146)3.16344447
24Progressive inability to walk (HP:0002505)3.14112599
25Generalized tonic-clonic seizures (HP:0002069)3.10290709
26Spastic gait (HP:0002064)3.07417939
27Absence seizures (HP:0002121)3.00880330
28Onion bulb formation (HP:0003383)3.00046403
29Insidious onset (HP:0003587)2.95742436
30Termporal pattern (HP:0011008)2.95742436
31Dysmetric saccades (HP:0000641)2.93314924
32Postural instability (HP:0002172)2.92933045
33Ankle clonus (HP:0011448)2.88342805
34Absent speech (HP:0001344)2.80599939
35Abnormal drinking behavior (HP:0030082)2.77832179
36Polydipsia (HP:0001959)2.77832179
37Truncal ataxia (HP:0002078)2.66481712
38Mutism (HP:0002300)2.64371628
39Abnormality of aromatic amino acid family metabolism (HP:0004338)2.60470231
40Hyperventilation (HP:0002883)2.59192752
41Diplopia (HP:0000651)2.58056632
42Abnormality of binocular vision (HP:0011514)2.58056632
43J-shaped sella turcica (HP:0002680)2.52876720
44Slow saccadic eye movements (HP:0000514)2.52705141
45Psychosis (HP:0000709)2.51421275
46Impaired smooth pursuit (HP:0007772)2.50572287
47Confusion (HP:0001289)2.50516289
48Status epilepticus (HP:0002133)2.48383394
49Depression (HP:0000716)2.46874349
50Excessive salivation (HP:0003781)2.44238538
51Drooling (HP:0002307)2.44238538
52Exotropia (HP:0000577)2.43876253
53Neuronal loss in central nervous system (HP:0002529)2.40143781
54Clumsiness (HP:0002312)2.38020709
55Sensory axonal neuropathy (HP:0003390)2.37888810
56Epileptiform EEG discharges (HP:0011182)2.35335744
57Large for gestational age (HP:0001520)2.34917282
58Aplasia involving bones of the extremities (HP:0009825)2.34792275
59Aplasia involving bones of the upper limbs (HP:0009823)2.34792275
60Aplasia of the phalanges of the hand (HP:0009802)2.34792275
61Congenital stationary night blindness (HP:0007642)2.34689619
62Lower limb muscle weakness (HP:0007340)2.34561501
63Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.33803079
64Anxiety (HP:0000739)2.33587132
65Obstructive sleep apnea (HP:0002870)2.29897399
66Hemiparesis (HP:0001269)2.28251667
67Congenital sensorineural hearing impairment (HP:0008527)2.28103937
68Postural tremor (HP:0002174)2.25982052
69Blue irides (HP:0000635)2.22864938
70Abnormal eating behavior (HP:0100738)2.22398813
71Urinary bladder sphincter dysfunction (HP:0002839)2.22224435
72Akinesia (HP:0002304)2.20208499
73Prolonged QT interval (HP:0001657)2.18992676
74Generalized myoclonic seizures (HP:0002123)2.18113052
75Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.17882692
76Abnormality of glycosphingolipid metabolism (HP:0004343)2.17344433
77Abnormality of glycolipid metabolism (HP:0010969)2.17344433
78Abnormality of liposaccharide metabolism (HP:0010968)2.17344433
79Hyperlipoproteinemia (HP:0010980)2.17228732
80Limb dystonia (HP:0002451)2.15978154
81EEG with generalized epileptiform discharges (HP:0011198)2.15218893
82Decreased subcutaneous fat (HP:0001002)2.14232991
83Impaired vibration sensation in the lower limbs (HP:0002166)2.13831529
84Metabolic alkalosis (HP:0200114)2.11857622
85Abnormality of ocular smooth pursuit (HP:0000617)2.11681266
86Increased circulating renin level (HP:0000848)2.10458712
87Parakeratosis (HP:0001036)2.08842004
88Axonal loss (HP:0003447)2.07238421
89Syncope (HP:0001279)2.07021833
90Lower limb asymmetry (HP:0100559)2.05777447
91Abnormality of renin-angiotensin system (HP:0000847)2.04462763
92Dysostosis multiplex (HP:0000943)2.02100937
93Abnormality of salivation (HP:0100755)2.01711116
94Ketoacidosis (HP:0001993)2.01024670
95Urinary urgency (HP:0000012)2.00949510
96Increased cerebral lipofuscin (HP:0011813)1.99390794
97Focal dystonia (HP:0004373)1.98648128
98Ventricular fibrillation (HP:0001663)1.98086409
99Polyuria (HP:0000103)1.96192223
100Widely spaced teeth (HP:0000687)1.95871108
101Hypomagnesemia (HP:0002917)1.94497822
102Morphological abnormality of the pyramidal tract (HP:0002062)1.93443143
103Thickened helices (HP:0000391)1.91748833
104Decreased circulating renin level (HP:0003351)1.90685164
105Spastic tetraparesis (HP:0001285)1.90663837
106Retinal dysplasia (HP:0007973)1.90385453
107Gait ataxia (HP:0002066)1.88312750
108Horizontal nystagmus (HP:0000666)1.87901851
109Inability to walk (HP:0002540)1.86360807
110Hypsarrhythmia (HP:0002521)1.85609196
111Clonus (HP:0002169)1.84876103
112Bulbous nose (HP:0000414)1.84510277
113Abnormality of saccadic eye movements (HP:0000570)1.84480811
114Torticollis (HP:0000473)1.83449335
115Urinary incontinence (HP:0000020)1.83150883
116Abnormal EKG (HP:0003115)1.83106805
117Poor eye contact (HP:0000817)1.82695406
118Abnormality of magnesium homeostasis (HP:0004921)1.82606918
119Genetic anticipation (HP:0003743)1.80787465
120Rapidly progressive (HP:0003678)1.80102636
121Abnormal social behavior (HP:0012433)1.78891648
122Impaired social interactions (HP:0000735)1.78891648
123Abnormal urine output (HP:0012590)1.78360117
124Increased neuronal autofluorescent lipopigment (HP:0002074)1.77238849
125Lower limb amyotrophy (HP:0007210)1.76473212
126Conical tooth (HP:0000698)1.76468729
127Bowel incontinence (HP:0002607)1.74901739
128Hypothermia (HP:0002045)1.74197895
129Mask-like facies (HP:0000298)1.74138081
130Hemiplegia (HP:0002301)1.74103935
131Conjugated hyperbilirubinemia (HP:0002908)1.74096535
132Stereotypic behavior (HP:0000733)1.73215033
133Sleep apnea (HP:0010535)1.72960041
134Bradykinesia (HP:0002067)1.72951549
135Rigidity (HP:0002063)1.70943156
136Amblyopia (HP:0000646)1.70645938
137Xanthomatosis (HP:0000991)1.69969928
138Cerebral hemorrhage (HP:0001342)1.69728638
139Megalencephaly (HP:0001355)1.68372835
140Abnormal large intestine physiology (HP:0012700)1.68261518
141Anosmia (HP:0000458)1.67192067
142Agitation (HP:0000713)1.66641747
143Pheochromocytoma (HP:0002666)1.66148211
144Hyperaldosteronism (HP:0000859)1.64853158
145Type II lissencephaly (HP:0007260)1.63742480
146Glomerulonephritis (HP:0000099)1.62538548
147Impaired vibratory sensation (HP:0002495)1.61177883
148Decreased central vision (HP:0007663)1.60216720
149Hyperthyroidism (HP:0000836)1.59128334
150Keratoconus (HP:0000563)1.58870026
151Increased corneal curvature (HP:0100692)1.58870026
152Abnormality of the renal cortex (HP:0011035)1.58068996
153Abnormality of renal excretion (HP:0011036)1.55546221
154Fragile nails (HP:0001808)1.54827491

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.32442114
2EPHA43.76629624
3NTRK33.33564678
4STK393.12046061
5PRPF4B2.73574870
6ADRBK22.51468040
7INSRR2.48845818
8OXSR12.48256836
9EPHB12.41333616
10RIPK42.35218330
11CASK2.34755322
12WNK32.34508454
13MAP3K92.16731377
14FES2.03300897
15TNIK2.01151559
16NTRK11.99164245
17CAMKK21.93311719
18GRK11.89924581
19DAPK21.72691692
20MAP3K41.71625788
21PKN11.67001503
22PAK61.66113524
23PINK11.63192642
24KSR21.59507491
25TIE11.54890198
26TYRO31.51203173
27WNK11.50175478
28MAP3K131.47691020
29CAMK2B1.47277630
30ERN11.39909113
31EPHA31.39235204
32MARK11.38787300
33CDK51.37577018
34PRKD31.34107018
35ARAF1.33522044
36MAP2K71.32408072
37CDK191.29042805
38MINK11.27688850
39MAPKAPK51.25943975
40CAMKK11.25341759
41BRD41.22932554
42BMPR21.21938618
43PNCK1.21786079
44GRK71.21660485
45GRK51.21603078
46NTRK21.20921478
47WNK41.18889903
48UHMK11.16108181
49ADRBK11.11347607
50MAP3K21.08550948
51CAMK2A1.07261453
52MAPK131.06677358
53SGK4941.02732184
54SGK2231.02732184
55PDPK11.01128128
56MAPK151.00839976
57STK111.00191616
58FGR0.98355141
59SGK20.97792844
60MAP2K40.96337974
61MARK20.95857456
62NEK60.94732017
63CSNK1G20.94229957
64BMPR1B0.93990486
65KSR10.92674339
66MAP2K60.92284732
67SIK20.90316463
68PLK20.89653546
69CAMK2D0.86570276
70PHKG10.85181330
71PHKG20.85181330
72PRKCZ0.84538579
73TXK0.84110774
74PRKD20.83150204
75BCR0.82366303
76PRKCG0.82333596
77PRKCQ0.79223265
78PDK10.77403489
79CSNK1G30.76053627
80PTK60.75756709
81PTK2B0.75752178
82CSNK1A1L0.75133963
83CDK140.74924777
84CDK150.72248183
85ITK0.71942673
86CAMK2G0.71883132
87SGK10.71852914
88PRKD10.71031615
89PRKCA0.70657165
90FYN0.69694097
91MAP2K10.69581207
92PRKG20.69058588
93CDK180.69055134
94ICK0.68484190
95CAMK1G0.67841725
96PRKCE0.65944332
97MAP3K10.64106056
98CDK11A0.63447450
99ROCK20.63108997
100ACVR1B0.62894867
101PRKACA0.61341774
102MAPKAPK30.61304777
103MOS0.60852597
104DAPK10.58609434
105TLK10.58308186
106PDGFRB0.57578505
107PAK30.57274599
108CAMK40.56572751
109DMPK0.55886584
110CAMK10.55406959
111PRKG10.54479016
112FGFR20.54268630
113PRKCH0.53928565
114CSNK1A10.53775766
115STK380.53591491
116TNK20.53358454
117RET0.52308179
118CDK30.52064110
119MAPK120.51754980
120AKT30.51178986
121LMTK20.49125225
122FGFR30.48986048
123DYRK1A0.48279474
124TRPM70.48217630
125PRKCB0.47716310
126PRKAA20.47023576
127PRKACG0.45110873
128PRKAA10.44308912
129CSNK1G10.44093981
130MAP2K20.43657188
131RPS6KA30.43273924
132RAF10.42463455
133TAOK10.41662006
134MAP3K120.41456680
135MAPK70.40050959
136PASK0.39054209
137CSNK1D0.39040083
138MAP3K70.38858919
139SGK30.37771311
140HIPK20.37481084

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.93800844
2Glutamatergic synapse_Homo sapiens_hsa047242.84298874
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.81098222
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.42405577
5Olfactory transduction_Homo sapiens_hsa047402.41433243
6Morphine addiction_Homo sapiens_hsa050322.39207970
7Long-term potentiation_Homo sapiens_hsa047202.36080898
8Synaptic vesicle cycle_Homo sapiens_hsa047212.27270200
9GABAergic synapse_Homo sapiens_hsa047272.24956851
10Circadian entrainment_Homo sapiens_hsa047132.13585629
11Amphetamine addiction_Homo sapiens_hsa050312.04261846
12Salivary secretion_Homo sapiens_hsa049701.96075949
13Long-term depression_Homo sapiens_hsa047301.81712765
14Dopaminergic synapse_Homo sapiens_hsa047281.79746351
15Serotonergic synapse_Homo sapiens_hsa047261.76730069
16Renin secretion_Homo sapiens_hsa049241.75035200
17Collecting duct acid secretion_Homo sapiens_hsa049661.74663277
18Cholinergic synapse_Homo sapiens_hsa047251.72618857
19Taste transduction_Homo sapiens_hsa047421.61006816
20Butanoate metabolism_Homo sapiens_hsa006501.59068219
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.58584808
22Vitamin B6 metabolism_Homo sapiens_hsa007501.55864132
23Gastric acid secretion_Homo sapiens_hsa049711.53787884
24Axon guidance_Homo sapiens_hsa043601.51841159
25Primary bile acid biosynthesis_Homo sapiens_hsa001201.47354605
26Oxytocin signaling pathway_Homo sapiens_hsa049211.46874990
27Bile secretion_Homo sapiens_hsa049761.45967877
28Ether lipid metabolism_Homo sapiens_hsa005651.43628578
29Cocaine addiction_Homo sapiens_hsa050301.42411823
30Calcium signaling pathway_Homo sapiens_hsa040201.38804629
31Insulin secretion_Homo sapiens_hsa049111.34943020
32Histidine metabolism_Homo sapiens_hsa003401.34242619
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.32467408
34Aldosterone synthesis and secretion_Homo sapiens_hsa049251.28525429
35Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.23305208
36ABC transporters_Homo sapiens_hsa020101.19569742
37Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.19548835
38GnRH signaling pathway_Homo sapiens_hsa049121.19519280
39Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17872884
40Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.17228013
41Phospholipase D signaling pathway_Homo sapiens_hsa040721.14542494
42Type II diabetes mellitus_Homo sapiens_hsa049301.12556707
43Tryptophan metabolism_Homo sapiens_hsa003801.10449738
44Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.10438882
45cAMP signaling pathway_Homo sapiens_hsa040241.10143978
46Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.07611896
47Gap junction_Homo sapiens_hsa045401.07467906
48Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.07284790
49Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04147554
50Vibrio cholerae infection_Homo sapiens_hsa051101.03783380
51Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.03305681
52Choline metabolism in cancer_Homo sapiens_hsa052311.02812106
53Pancreatic secretion_Homo sapiens_hsa049721.02014264
54ErbB signaling pathway_Homo sapiens_hsa040121.00671589
55Vascular smooth muscle contraction_Homo sapiens_hsa042701.00041346
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.96659869
57cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95272092
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.94323608
59Glioma_Homo sapiens_hsa052140.93814847
60Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.93283975
61Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.93201413
62Retinol metabolism_Homo sapiens_hsa008300.92521193
63Sulfur metabolism_Homo sapiens_hsa009200.91586860
64Dorso-ventral axis formation_Homo sapiens_hsa043200.88513454
65Sphingolipid signaling pathway_Homo sapiens_hsa040710.88177308
66Arginine biosynthesis_Homo sapiens_hsa002200.88038750
67Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.87748217
68beta-Alanine metabolism_Homo sapiens_hsa004100.86606932
69Linoleic acid metabolism_Homo sapiens_hsa005910.84613366
70Lysosome_Homo sapiens_hsa041420.82405842
71MAPK signaling pathway_Homo sapiens_hsa040100.81570875
72Steroid hormone biosynthesis_Homo sapiens_hsa001400.81219832
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81163133
74Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.79507360
75Renal cell carcinoma_Homo sapiens_hsa052110.78844039
76Phototransduction_Homo sapiens_hsa047440.77708953
77Mineral absorption_Homo sapiens_hsa049780.76961093
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.76665935
79Cardiac muscle contraction_Homo sapiens_hsa042600.76605689
80Estrogen signaling pathway_Homo sapiens_hsa049150.76294592
81VEGF signaling pathway_Homo sapiens_hsa043700.75824806
82Ras signaling pathway_Homo sapiens_hsa040140.75767499
83Prion diseases_Homo sapiens_hsa050200.74733586
84Chemokine signaling pathway_Homo sapiens_hsa040620.74170976
85Endocytosis_Homo sapiens_hsa041440.72742055
86Circadian rhythm_Homo sapiens_hsa047100.72527210
87Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.71787933
88Sphingolipid metabolism_Homo sapiens_hsa006000.71163494
89B cell receptor signaling pathway_Homo sapiens_hsa046620.70835078
90Complement and coagulation cascades_Homo sapiens_hsa046100.70490900
91Chemical carcinogenesis_Homo sapiens_hsa052040.70229014
92Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67847750
93Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.67839950
94Arginine and proline metabolism_Homo sapiens_hsa003300.66998680
95Rheumatoid arthritis_Homo sapiens_hsa053230.64478736
96Glycerolipid metabolism_Homo sapiens_hsa005610.63111015
97Fatty acid elongation_Homo sapiens_hsa000620.62721924
98Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.61874312
99Alzheimers disease_Homo sapiens_hsa050100.61421182
100Melanogenesis_Homo sapiens_hsa049160.60408560
101Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.60262904
102PPAR signaling pathway_Homo sapiens_hsa033200.59417228
103Dilated cardiomyopathy_Homo sapiens_hsa054140.59129302
104Parkinsons disease_Homo sapiens_hsa050120.57394248
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56137457
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.56047421
107Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.55364871
108Steroid biosynthesis_Homo sapiens_hsa001000.54970423
109Pentose and glucuronate interconversions_Homo sapiens_hsa000400.54407560
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.53524326
111Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.53067749
112Carbohydrate digestion and absorption_Homo sapiens_hsa049730.53004145
113Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.51730538
114African trypanosomiasis_Homo sapiens_hsa051430.50818533
115Osteoclast differentiation_Homo sapiens_hsa043800.49750758
116Thyroid hormone synthesis_Homo sapiens_hsa049180.49252848
117Glycosaminoglycan degradation_Homo sapiens_hsa005310.49183780
118Rap1 signaling pathway_Homo sapiens_hsa040150.47343202
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47072140
120Glucagon signaling pathway_Homo sapiens_hsa049220.46913111
121Caffeine metabolism_Homo sapiens_hsa002320.46886052
122Inositol phosphate metabolism_Homo sapiens_hsa005620.46111822
123Fatty acid degradation_Homo sapiens_hsa000710.45879068
124Alcoholism_Homo sapiens_hsa050340.45531562
125Nitrogen metabolism_Homo sapiens_hsa009100.45388087
126Regulation of actin cytoskeleton_Homo sapiens_hsa048100.44963807
127Phagosome_Homo sapiens_hsa041450.44325937
128Non-small cell lung cancer_Homo sapiens_hsa052230.44105561
129Platelet activation_Homo sapiens_hsa046110.44078196
130T cell receptor signaling pathway_Homo sapiens_hsa046600.42550307
131Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.42478107
132Peroxisome_Homo sapiens_hsa041460.41634440
133Oxidative phosphorylation_Homo sapiens_hsa001900.40051734
134Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.39352870
135SNARE interactions in vesicular transport_Homo sapiens_hsa041300.38489741
136Ovarian steroidogenesis_Homo sapiens_hsa049130.37613396
137Fat digestion and absorption_Homo sapiens_hsa049750.35636440
138Salmonella infection_Homo sapiens_hsa051320.34419802
139Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.30581480
140Protein digestion and absorption_Homo sapiens_hsa049740.28368260

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