ZDHHC17

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)5.63744328
2synaptic vesicle maturation (GO:0016188)5.34651373
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.04402713
4locomotory exploration behavior (GO:0035641)4.97727241
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.90497834
6synaptic vesicle exocytosis (GO:0016079)4.87643986
7neuronal action potential propagation (GO:0019227)4.72898214
8regulation of synaptic vesicle exocytosis (GO:2000300)4.64340337
9glutamate secretion (GO:0014047)4.56001274
10neuron cell-cell adhesion (GO:0007158)4.53627608
11vocalization behavior (GO:0071625)4.52362370
12regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.26690098
13pyrimidine nucleobase catabolic process (GO:0006208)4.23056714
14ionotropic glutamate receptor signaling pathway (GO:0035235)4.21902288
15synaptic vesicle docking involved in exocytosis (GO:0016081)4.18912521
16regulation of synaptic vesicle transport (GO:1902803)4.05727123
17neurotransmitter secretion (GO:0007269)4.05344285
18gamma-aminobutyric acid transport (GO:0015812)4.02052100
19protein localization to synapse (GO:0035418)4.01473720
20regulation of glutamate receptor signaling pathway (GO:1900449)3.95582205
21glutamate receptor signaling pathway (GO:0007215)3.91404216
22synaptic transmission, glutamatergic (GO:0035249)3.90947256
23neural tube formation (GO:0001841)3.88672380
24regulation of neuronal synaptic plasticity (GO:0048168)3.85889233
25neuron-neuron synaptic transmission (GO:0007270)3.82941556
26cellular potassium ion homeostasis (GO:0030007)3.81027090
27exploration behavior (GO:0035640)3.74206654
28regulation of long-term neuronal synaptic plasticity (GO:0048169)3.72054509
29membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.68767179
30layer formation in cerebral cortex (GO:0021819)3.65732809
31regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.64440425
32long-term memory (GO:0007616)3.58209271
33neurotransmitter-gated ion channel clustering (GO:0072578)3.57097795
34regulation of synapse structural plasticity (GO:0051823)3.55993111
35cerebellar Purkinje cell differentiation (GO:0021702)3.54676075
36regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.50622438
37transmission of nerve impulse (GO:0019226)3.47124847
38establishment of nucleus localization (GO:0040023)3.45978556
39sodium ion export (GO:0071436)3.44845896
40neurotransmitter transport (GO:0006836)3.43711138
41regulation of excitatory postsynaptic membrane potential (GO:0060079)3.43034918
42cerebellar granule cell differentiation (GO:0021707)3.42358683
43dendritic spine morphogenesis (GO:0060997)3.40943047
44central nervous system projection neuron axonogenesis (GO:0021952)3.37555604
45positive regulation of membrane potential (GO:0045838)3.35899322
46positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.33723564
47neuromuscular process controlling posture (GO:0050884)3.32797024
48neuron recognition (GO:0008038)3.30163483
49regulation of postsynaptic membrane potential (GO:0060078)3.29742521
50L-amino acid import (GO:0043092)3.28274603
51presynaptic membrane assembly (GO:0097105)3.28242198
52negative regulation of synaptic transmission, GABAergic (GO:0032229)3.27979944
53gamma-aminobutyric acid signaling pathway (GO:0007214)3.27673084
54nucleobase catabolic process (GO:0046113)3.26821191
55regulation of neurotransmitter secretion (GO:0046928)3.26644013
56G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.25202945
57adult walking behavior (GO:0007628)3.25199931
58neurotransmitter uptake (GO:0001504)3.22788198
59dendrite morphogenesis (GO:0048813)3.22483253
60presynaptic membrane organization (GO:0097090)3.21049701
61regulation of voltage-gated calcium channel activity (GO:1901385)3.20207391
62long-term synaptic potentiation (GO:0060291)3.18833577
63axonal fasciculation (GO:0007413)3.18522516
64prepulse inhibition (GO:0060134)3.17607657
65membrane hyperpolarization (GO:0060081)3.17017830
66positive regulation of synapse maturation (GO:0090129)3.13217688
67negative regulation of neurotransmitter secretion (GO:0046929)3.12635457
68regulation of synaptic transmission, glutamatergic (GO:0051966)3.12530201
69membrane depolarization during action potential (GO:0086010)3.12025384
70olfactory bulb development (GO:0021772)3.12010648
71regulation of synaptic plasticity (GO:0048167)3.11446408
72regulation of neurotransmitter levels (GO:0001505)3.11208128
73synaptic vesicle endocytosis (GO:0048488)3.10855231
74neuromuscular process controlling balance (GO:0050885)3.10254608
75activation of protein kinase A activity (GO:0034199)3.09560122
76regulation of neurotransmitter transport (GO:0051588)3.08187323
77proline transport (GO:0015824)3.08016471
78regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.07051873
79cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.06256490
80glycine transport (GO:0015816)3.04555516
81auditory behavior (GO:0031223)3.04074244
82nerve growth factor signaling pathway (GO:0038180)3.03926956
83positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.03722821
84regulation of dendritic spine morphogenesis (GO:0061001)3.03666341
85synapse assembly (GO:0007416)3.01605483
86potassium ion import (GO:0010107)3.01228396
87central nervous system neuron axonogenesis (GO:0021955)3.01020826
88neuronal ion channel clustering (GO:0045161)3.00821089
89membrane depolarization (GO:0051899)2.98641908
90negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.95848562
91cyclic nucleotide catabolic process (GO:0009214)2.95517006
92mechanosensory behavior (GO:0007638)2.95259476
93negative regulation of cytosolic calcium ion concentration (GO:0051481)2.93408049
94postsynaptic membrane organization (GO:0001941)2.93240289
95axon ensheathment in central nervous system (GO:0032291)2.92835467
96central nervous system myelination (GO:0022010)2.92835467
97response to auditory stimulus (GO:0010996)2.92514307
98positive regulation of synaptic transmission, GABAergic (GO:0032230)2.92053843
99cell communication by electrical coupling (GO:0010644)2.89982404
100positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.89670775
101cAMP catabolic process (GO:0006198)2.89185643
102positive regulation of dendritic spine morphogenesis (GO:0061003)2.88950838
103vesicle transport along microtubule (GO:0047496)2.87742960
104regulation of vesicle fusion (GO:0031338)2.86281096
105regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.85891766
106establishment of protein localization to Golgi (GO:0072600)2.85780957
107mating behavior (GO:0007617)2.85757931
108phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.85391702
109innervation (GO:0060384)2.85046520
110negative regulation of neurotransmitter transport (GO:0051589)2.84339363
111positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.83565947
112response to histamine (GO:0034776)2.80241708
113nucleus localization (GO:0051647)2.79443986
114potassium ion homeostasis (GO:0055075)2.79314974
115learning (GO:0007612)2.78732709
116synaptic transmission (GO:0007268)2.78669930
117protein targeting to Golgi (GO:0000042)2.78431447
118synapse organization (GO:0050808)2.77805606
119positive regulation of neurotransmitter transport (GO:0051590)2.76856998
120neuromuscular process (GO:0050905)2.75947701
121microtubule anchoring (GO:0034453)2.75360891
122protein K11-linked deubiquitination (GO:0035871)2.70481297
123startle response (GO:0001964)2.70444173
124calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.66321495
125cell differentiation in hindbrain (GO:0021533)2.64318478
126cerebral cortex radially oriented cell migration (GO:0021799)2.63854017
127retrograde transport, vesicle recycling within Golgi (GO:0000301)2.63705879
128activated T cell proliferation (GO:0050798)2.62088769
129suckling behavior (GO:0001967)2.62035806
130regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.60996635
131establishment of mitochondrion localization (GO:0051654)2.54711254
132axonogenesis (GO:0007409)2.53323094
133negative regulation of oligodendrocyte differentiation (GO:0048715)2.52861512
134monoubiquitinated protein deubiquitination (GO:0035520)2.51003637
135organelle transport along microtubule (GO:0072384)2.48928341
136retinal cone cell development (GO:0046549)2.48901898
137cytoplasmic mRNA processing body assembly (GO:0033962)2.46997270
138regulation of dendritic spine development (GO:0060998)2.46396133
139Golgi to endosome transport (GO:0006895)2.45776904
140regulation of Rac protein signal transduction (GO:0035020)2.44770103

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.90968765
2GBX2_23144817_ChIP-Seq_PC3_Human3.68496345
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.00744223
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.00067980
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.89185783
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.77851835
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.71922862
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.60354690
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.60354690
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.47698594
11MTF2_20144788_ChIP-Seq_MESCs_Mouse2.47486412
12SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.46413290
13DROSHA_22980978_ChIP-Seq_HELA_Human2.44705846
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.42314041
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.40897168
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40468087
17REST_21632747_ChIP-Seq_MESCs_Mouse2.39444410
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.38036628
19RARB_27405468_Chip-Seq_BRAIN_Mouse2.37643369
20EED_16625203_ChIP-ChIP_MESCs_Mouse2.16748255
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.15773752
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.14128153
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.09870826
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.09809666
25BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.04892123
26AR_21572438_ChIP-Seq_LNCaP_Human1.94062188
27REST_18959480_ChIP-ChIP_MESCs_Mouse1.92004720
28TAF15_26573619_Chip-Seq_HEK293_Human1.84286040
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.79919981
30* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.79314757
31GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.77980044
32CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.76342766
33IKZF1_21737484_ChIP-ChIP_HCT116_Human1.75401101
34* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.73080188
35* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66958655
36* SMAD4_21799915_ChIP-Seq_A2780_Human1.66917704
37* EWS_26573619_Chip-Seq_HEK293_Human1.63281194
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.63140861
39MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.60166476
40NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.59744518
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.59369648
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53685868
43POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.46353650
44EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45349878
45P300_19829295_ChIP-Seq_ESCs_Human1.45182817
46PCGF2_27294783_Chip-Seq_ESCs_Mouse1.45106404
47SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.44195910
48SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41809284
49OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41241376
50SMAD_19615063_ChIP-ChIP_OVARY_Human1.41210427
51PIAS1_25552417_ChIP-Seq_VCAP_Human1.41090481
52GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40231416
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.39721694
54PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.35589957
55FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.35547372
56ZNF274_21170338_ChIP-Seq_K562_Hela1.35120245
57CDX2_19796622_ChIP-Seq_MESCs_Mouse1.33650550
58EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.33172466
59RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.32970366
60STAT3_23295773_ChIP-Seq_U87_Human1.32214092
61* SOX2_21211035_ChIP-Seq_LN229_Gbm1.32121708
62* FLI1_21867929_ChIP-Seq_TH2_Mouse1.30151761
63SUZ12_27294783_Chip-Seq_NPCs_Mouse1.29802164
64NR3C1_23031785_ChIP-Seq_PC12_Mouse1.28735300
65AR_25329375_ChIP-Seq_VCAP_Human1.27811079
66EZH2_27294783_Chip-Seq_NPCs_Mouse1.27713644
67POU3F2_20337985_ChIP-ChIP_501MEL_Human1.27113661
68E2F1_18555785_Chip-Seq_ESCs_Mouse1.26039786
69PCGF2_27294783_Chip-Seq_NPCs_Mouse1.25470752
70P53_22387025_ChIP-Seq_ESCs_Mouse1.25339961
71CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24425609
72ERG_21242973_ChIP-ChIP_JURKAT_Human1.22946275
73CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.22898857
74WT1_19549856_ChIP-ChIP_CCG9911_Human1.22887801
75VDR_22108803_ChIP-Seq_LS180_Human1.22641956
76CMYC_18555785_Chip-Seq_ESCs_Mouse1.22115682
77* RING1B_27294783_Chip-Seq_ESCs_Mouse1.21987339
78* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.21974440
79* CBP_20019798_ChIP-Seq_JUKART_Human1.21974440
80CBX2_27304074_Chip-Seq_ESCs_Mouse1.21510757
81AR_19668381_ChIP-Seq_PC3_Human1.21369292
82BCAT_22108803_ChIP-Seq_LS180_Human1.21346809
83IGF1R_20145208_ChIP-Seq_DFB_Human1.21232704
84WT1_25993318_ChIP-Seq_PODOCYTE_Human1.20275630
85* NRF2_20460467_ChIP-Seq_MEFs_Mouse1.19676472
86* NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.19676472
87LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18377592
88ZNF217_24962896_ChIP-Seq_MCF-7_Human1.18218147
89KDM2B_26808549_Chip-Seq_REH_Human1.17819811
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17670794
91STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17579180
92TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16905976
93TCF4_23295773_ChIP-Seq_U87_Human1.16542656
94TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.14918433
95ARNT_22903824_ChIP-Seq_MCF-7_Human1.13956220
96* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13126301
97* TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.12924289
98* P53_22127205_ChIP-Seq_FIBROBLAST_Human1.12393583
99PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.12309502
100SUZ12_18555785_Chip-Seq_ESCs_Mouse1.11907237
101BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11583482
102RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11135779
103VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.10416925
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.09673723
105AHR_22903824_ChIP-Seq_MCF-7_Human1.09281098
106NFE2_27457419_Chip-Seq_LIVER_Mouse1.08996380
107EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.08302369
108RING1B_27294783_Chip-Seq_NPCs_Mouse1.07809149
109TP53_16413492_ChIP-PET_HCT116_Human1.07691773
110TAL1_26923725_Chip-Seq_HPCs_Mouse1.06869859
111YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06575338
112SOX9_26525672_Chip-Seq_HEART_Mouse1.04562473
113DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03765124
114WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.03446608
115TCF4_22108803_ChIP-Seq_LS180_Human1.02899792
116STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.02479056
117* JUN_21703547_ChIP-Seq_K562_Human1.02212889
118RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.02211803
119FUS_26573619_Chip-Seq_HEK293_Human1.01208408
120CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00869912
121RUNX2_22187159_ChIP-Seq_PCA_Human1.00637104
122* KLF5_20875108_ChIP-Seq_MESCs_Mouse1.00375343
123MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98924788
124RNF2_27304074_Chip-Seq_NSC_Mouse0.98416461
125TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98060729
126PRDM14_20953172_ChIP-Seq_ESCs_Human0.97669488
127TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97630476
128SMAD4_21741376_ChIP-Seq_HESCs_Human0.97184668
129* NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97004641
130TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.95577457
131ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.95536353
132ER_23166858_ChIP-Seq_MCF-7_Human0.95352161
133SMAD3_21741376_ChIP-Seq_ESCs_Human0.93590950
134UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.92529642
135SMAD3_21741376_ChIP-Seq_HESCs_Human0.92099493
136TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91693064
137TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.91661737
138RXR_22108803_ChIP-Seq_LS180_Human0.90512261
139KDM2B_26808549_Chip-Seq_K562_Human0.90411324
140TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.90286421
141NANOG_18555785_Chip-Seq_ESCs_Mouse0.88317649
142TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85746671

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.73945482
2MP0003880_abnormal_central_pattern4.44577499
3MP0003635_abnormal_synaptic_transmissio3.84292800
4MP0004270_analgesia3.72125610
5MP0009046_muscle_twitch3.35098075
6MP0009745_abnormal_behavioral_response3.20939532
7MP0002064_seizures3.14936388
8MP0002063_abnormal_learning/memory/cond3.00029421
9MP0001968_abnormal_touch/_nociception2.88614204
10MP0002272_abnormal_nervous_system2.80348982
11MP0005423_abnormal_somatic_nervous2.79363529
12MP0001486_abnormal_startle_reflex2.76270695
13MP0002822_catalepsy2.74875775
14MP0002572_abnormal_emotion/affect_behav2.61823560
15MP0002734_abnormal_mechanical_nocicepti2.57918094
16MP0008877_abnormal_DNA_methylation2.33392849
17MP0002735_abnormal_chemical_nociception2.21689450
18MP0008569_lethality_at_weaning2.20805175
19MP0002009_preneoplasia2.18798601
20MP0002736_abnormal_nociception_after2.18467828
21MP0002067_abnormal_sensory_capabilities2.07137823
22MP0008057_abnormal_DNA_replication2.02566662
23MP0001970_abnormal_pain_threshold1.96183234
24MP0001501_abnormal_sleep_pattern1.96162055
25MP0003121_genomic_imprinting1.94683640
26MP0002733_abnormal_thermal_nociception1.94562095
27MP0005551_abnormal_eye_electrophysiolog1.94085155
28MP0001440_abnormal_grooming_behavior1.92400757
29MP0000778_abnormal_nervous_system1.83025936
30MP0003329_amyloid_beta_deposits1.82909063
31MP0004885_abnormal_endolymph1.79759860
32MP0004924_abnormal_behavior1.78642024
33MP0005386_behavior/neurological_phenoty1.78642024
34MP0009780_abnormal_chondrocyte_physiolo1.71474379
35MP0000920_abnormal_myelination1.70774643
36MP0002184_abnormal_innervation1.69978731
37MP0000955_abnormal_spinal_cord1.66390625
38MP0005248_abnormal_Harderian_gland1.64329205
39MP0005646_abnormal_pituitary_gland1.64190308
40MP0004811_abnormal_neuron_physiology1.64113369
41MP0002557_abnormal_social/conspecific_i1.62716461
42MP0002882_abnormal_neuron_morphology1.56693312
43MP0006276_abnormal_autonomic_nervous1.56412779
44MP0002909_abnormal_adrenal_gland1.53640980
45MP0003633_abnormal_nervous_system1.53073239
46MP0002102_abnormal_ear_morphology1.50780035
47MP0001984_abnormal_olfaction1.50096535
48MP0004142_abnormal_muscle_tone1.48425820
49MP0003690_abnormal_glial_cell1.45628020
50MP0002066_abnormal_motor_capabilities/c1.43190932
51MP0002229_neurodegeneration1.37330305
52MP0003221_abnormal_cardiomyocyte_apopto1.34888398
53MP0004858_abnormal_nervous_system1.34462944
54MP0001905_abnormal_dopamine_level1.33043567
55MP0001529_abnormal_vocalization1.32386471
56MP0003631_nervous_system_phenotype1.32167749
57MP0001502_abnormal_circadian_rhythm1.29432232
58MP0004145_abnormal_muscle_electrophysio1.27786362
59MP0003890_abnormal_embryonic-extraembry1.26234572
60MP0003634_abnormal_glial_cell1.24750025
61MP0003787_abnormal_imprinting1.24486288
62MP0003122_maternal_imprinting1.23194655
63MP0005409_darkened_coat_color1.23117529
64MP0005645_abnormal_hypothalamus_physiol1.21641300
65MP0004742_abnormal_vestibular_system1.19539991
66MP0001188_hyperpigmentation1.16500383
67MP0006072_abnormal_retinal_apoptosis1.15095940
68MP0002152_abnormal_brain_morphology1.10949539
69MP0008995_early_reproductive_senescence1.08839313
70MP0003879_abnormal_hair_cell1.08256615
71MP0003632_abnormal_nervous_system1.08044263
72MP0002090_abnormal_vision1.04910107
73MP0000751_myopathy1.03097262
74MP0002751_abnormal_autonomic_nervous1.02468813
75MP0005253_abnormal_eye_physiology1.01324262
76MP0002752_abnormal_somatic_nervous0.99521453
77MP0001177_atelectasis0.98293492
78MP0005499_abnormal_olfactory_system0.97359945
79MP0005391_vision/eye_phenotype0.95174435
80MP0001299_abnormal_eye_distance/0.94660740
81MP0004043_abnormal_pH_regulation0.87184293
82MP0004085_abnormal_heartbeat0.86748139
83MP0001963_abnormal_hearing_physiology0.86515826
84MP0004215_abnormal_myocardial_fiber0.85222954
85MP0003567_abnormal_fetal_cardiomyocyte0.85106809
86MP0000631_abnormal_neuroendocrine_gland0.84932680
87MP0000013_abnormal_adipose_tissue0.83649742
88MP0008872_abnormal_physiological_respon0.83236567
89MP0008874_decreased_physiological_sensi0.82300124
90MP0002069_abnormal_eating/drinking_beha0.81721501
91MP0003136_yellow_coat_color0.81144862
92MP0008789_abnormal_olfactory_epithelium0.79118264
93MP0005171_absent_coat_pigmentation0.77987041
94MP0010386_abnormal_urinary_bladder0.77789915
95MP0002233_abnormal_nose_morphology0.73947049
96MP0001485_abnormal_pinna_reflex0.73681099
97MP0003938_abnormal_ear_development0.72087451
98MP0000604_amyloidosis0.71444079
99MP0005388_respiratory_system_phenotype0.71116289
100MP0002133_abnormal_respiratory_system0.71116289
101MP0003385_abnormal_body_wall0.70652679
102MP0002638_abnormal_pupillary_reflex0.70171558
103MP0000427_abnormal_hair_cycle0.70142397
104MP0005195_abnormal_posterior_eye0.69704405
105MP0000026_abnormal_inner_ear0.69430828
106MP0000569_abnormal_digit_pigmentation0.69123656
107MP0005535_abnormal_body_temperature0.67930806
108MP0005167_abnormal_blood-brain_barrier0.67600396
109MP0001293_anophthalmia0.66554146
110MP0005187_abnormal_penis_morphology0.65759642
111MP0001986_abnormal_taste_sensitivity0.64660476
112MP0000747_muscle_weakness0.64229763
113MP0003137_abnormal_impulse_conducting0.64204589
114MP0001943_abnormal_respiration0.62254807
115MP0005623_abnormal_meninges_morphology0.62009779
116MP0002837_dystrophic_cardiac_calcinosis0.61893643
117MP0004147_increased_porphyrin_level0.60099954
118MP0008961_abnormal_basal_metabolism0.58843306
119MP0004484_altered_response_of0.58128842
120MP0010769_abnormal_survival0.57722028
121MP0002082_postnatal_lethality0.56427873
122MP0010770_preweaning_lethality0.56427873
123MP0003861_abnormal_nervous_system0.54923683
124MP0005394_taste/olfaction_phenotype0.54296114

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.64155922
2Myokymia (HP:0002411)6.05039762
3Focal seizures (HP:0007359)5.17167906
4Epileptic encephalopathy (HP:0200134)4.60820411
5Action tremor (HP:0002345)4.53408597
6Progressive cerebellar ataxia (HP:0002073)4.49216839
7Febrile seizures (HP:0002373)4.34800276
8Visual hallucinations (HP:0002367)4.32331620
9Atonic seizures (HP:0010819)4.30589883
10Gaze-evoked nystagmus (HP:0000640)3.68690941
11Absence seizures (HP:0002121)3.60036359
12Broad-based gait (HP:0002136)3.48469737
13Supranuclear gaze palsy (HP:0000605)3.47463895
14Dialeptic seizures (HP:0011146)3.42839990
15Truncal ataxia (HP:0002078)3.34622229
16Ankle clonus (HP:0011448)3.32004962
17Dysmetria (HP:0001310)3.30268683
18Amyotrophic lateral sclerosis (HP:0007354)3.27390568
19Generalized tonic-clonic seizures (HP:0002069)3.23797103
20Scanning speech (HP:0002168)3.23317815
21Dysdiadochokinesis (HP:0002075)3.21701400
22Depression (HP:0000716)3.00196632
23Papillary thyroid carcinoma (HP:0002895)2.96586178
24Poor eye contact (HP:0000817)2.94135936
25Abnormality of the corticospinal tract (HP:0002492)2.91290390
26Spastic gait (HP:0002064)2.91264237
27Urinary bladder sphincter dysfunction (HP:0002839)2.87970585
28Anxiety (HP:0000739)2.86083869
29Intention tremor (HP:0002080)2.84969658
30Neurofibrillary tangles (HP:0002185)2.82897437
31Impaired vibration sensation in the lower limbs (HP:0002166)2.80374734
32Congenital stationary night blindness (HP:0007642)2.80009232
33Termporal pattern (HP:0011008)2.78271904
34Insidious onset (HP:0003587)2.78271904
35Hyperventilation (HP:0002883)2.77169944
36Pheochromocytoma (HP:0002666)2.76027052
37Impaired social interactions (HP:0000735)2.69601144
38Abnormal social behavior (HP:0012433)2.69601144
39Postural instability (HP:0002172)2.65753570
40Abnormal eating behavior (HP:0100738)2.61183778
41Hemiparesis (HP:0001269)2.60407777
42Excessive salivation (HP:0003781)2.58887991
43Drooling (HP:0002307)2.58887991
44Central scotoma (HP:0000603)2.56976681
45Degeneration of the lateral corticospinal tracts (HP:0002314)2.56947375
46Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.56947375
47Genetic anticipation (HP:0003743)2.54691543
48Mutism (HP:0002300)2.52416379
49Impaired smooth pursuit (HP:0007772)2.50106738
50Urinary urgency (HP:0000012)2.49892018
51Progressive inability to walk (HP:0002505)2.45983670
52Chronic hepatic failure (HP:0100626)2.43611561
53Cerebral inclusion bodies (HP:0100314)2.36464785
54Abnormality of ocular smooth pursuit (HP:0000617)2.32252851
55Dysmetric saccades (HP:0000641)2.32084350
56Abnormality of salivation (HP:0100755)2.32007369
57Neuroendocrine neoplasm (HP:0100634)2.30037076
58Volvulus (HP:0002580)2.26875984
59Abnormality of binocular vision (HP:0011514)2.25692136
60Diplopia (HP:0000651)2.25692136
61Hemiplegia (HP:0002301)2.24919615
62Lower limb muscle weakness (HP:0007340)2.23734304
63Polyphagia (HP:0002591)2.23146898
64Stereotypic behavior (HP:0000733)2.21447801
65Postural tremor (HP:0002174)2.20921310
66Abnormality of macular pigmentation (HP:0008002)2.20867337
67Megalencephaly (HP:0001355)2.20391445
68Epileptiform EEG discharges (HP:0011182)2.17366706
69Peripheral hypomyelination (HP:0007182)2.15806343
70Agitation (HP:0000713)2.15022309
71Absent speech (HP:0001344)2.14498644
72Torticollis (HP:0000473)2.14013917
73EEG with generalized epileptiform discharges (HP:0011198)2.13659789
74Pancreatic fibrosis (HP:0100732)2.13619845
75Thickened helices (HP:0000391)2.13324764
76Amblyopia (HP:0000646)2.13097336
77Papilledema (HP:0001085)2.11180992
78Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.10273548
79Short 4th metacarpal (HP:0010044)2.10273548
80Bradykinesia (HP:0002067)2.10177434
81Blue irides (HP:0000635)2.09676374
82Hepatoblastoma (HP:0002884)2.09274772
83Limb dystonia (HP:0002451)2.08755794
84Protruding tongue (HP:0010808)2.07915904
85Nephronophthisis (HP:0000090)2.07322803
86Thyroid carcinoma (HP:0002890)2.06917706
87Hypsarrhythmia (HP:0002521)2.04244639
88Vitreoretinal degeneration (HP:0000655)2.04207021
89Gait ataxia (HP:0002066)2.03269668
90Spastic paraplegia (HP:0001258)2.01916262
91Genital tract atresia (HP:0001827)1.99958093
92Paraplegia (HP:0010550)1.99172035
93Abnormality of the lower motor neuron (HP:0002366)1.98927602
94Pancreatic cysts (HP:0001737)1.98702735
95Focal dystonia (HP:0004373)1.98662987
96Abnormality of saccadic eye movements (HP:0000570)1.98063880
97Split foot (HP:0001839)1.98058027
98Inappropriate behavior (HP:0000719)1.96982681
99Clonus (HP:0002169)1.96664048
100Truncal obesity (HP:0001956)1.95650904
101Intestinal atresia (HP:0011100)1.93673113
102Onion bulb formation (HP:0003383)1.93157579
103Impaired vibratory sensation (HP:0002495)1.91447891
104Neuronal loss in central nervous system (HP:0002529)1.91306030
105Macroorchidism (HP:0000053)1.90799261
106Status epilepticus (HP:0002133)1.90177547
107Prolonged QT interval (HP:0001657)1.89998898
108Nephrogenic diabetes insipidus (HP:0009806)1.89735950
109Congenital primary aphakia (HP:0007707)1.89625853
110Menstrual irregularities (HP:0000858)1.88532297
111Generalized myoclonic seizures (HP:0002123)1.88190210
112Hypoplasia of the corpus callosum (HP:0002079)1.87539770
113Vaginal atresia (HP:0000148)1.87098696
114Abnormality of the renal medulla (HP:0100957)1.86000963
115Psychosis (HP:0000709)1.86000077
116Retinal dysplasia (HP:0007973)1.84967370
117Medial flaring of the eyebrow (HP:0010747)1.84542807
118Hip dysplasia (HP:0001385)1.83094761
119Specific learning disability (HP:0001328)1.82474696
120Incomplete penetrance (HP:0003829)1.81683756
121Heterotopia (HP:0002282)1.81439847
122Aplasia involving bones of the extremities (HP:0009825)1.81139248
123Aplasia involving bones of the upper limbs (HP:0009823)1.81139248
124Aplasia of the phalanges of the hand (HP:0009802)1.81139248
125Scotoma (HP:0000575)1.80841470
126Rigidity (HP:0002063)1.80777536
127Exotropia (HP:0000577)1.80659876
128Clumsiness (HP:0002312)1.78711113
129Widely spaced teeth (HP:0000687)1.78005141
130Morphological abnormality of the pyramidal tract (HP:0002062)1.77845484
131Poor coordination (HP:0002370)1.77745087
132Aqueductal stenosis (HP:0002410)1.77039250
133Abnormality of midbrain morphology (HP:0002418)1.76984880
134Molar tooth sign on MRI (HP:0002419)1.76984880
135Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.76889257
136Abnormality of the labia minora (HP:0012880)1.76620185
137Gait imbalance (HP:0002141)1.75056586
138Failure to thrive in infancy (HP:0001531)1.73525445
139Oligodactyly (hands) (HP:0001180)1.73254951
140Stomach cancer (HP:0012126)1.73112563
141True hermaphroditism (HP:0010459)1.72846718
142Thyroiditis (HP:0100646)1.72736176
143Cortical dysplasia (HP:0002539)1.72491487
144Inability to walk (HP:0002540)1.71279849
145Dyskinesia (HP:0100660)1.70958879
146Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.69301436
147Lissencephaly (HP:0001339)1.68127316
148Narrow forehead (HP:0000341)1.67456128
149Difficulty running (HP:0009046)1.66231176
150Postaxial hand polydactyly (HP:0001162)1.65155180
151Cutaneous finger syndactyly (HP:0010554)1.64844901
152Optic nerve hypoplasia (HP:0000609)1.62590202
153Cystic hygroma (HP:0000476)1.62437992

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.83991658
2EPHA43.43808703
3MAP3K93.05946314
4MAP3K42.79243599
5MARK12.63926751
6TNIK2.46243736
7MINK12.36009798
8BRD42.34456459
9EPHA32.25484351
10MAP2K72.19437776
11PAK62.10886806
12CASK2.05961227
13FRK2.05143176
14DAPK21.95738923
15NTRK21.87930852
16NTRK11.81146238
17KSR21.79812213
18CDK191.74850389
19PRKD31.70789702
20CAMKK11.69919459
21OXSR11.67396334
22WNK11.65784293
23MAP2K41.63646458
24ERBB31.60913588
25CDK51.60297387
26STK391.53272268
27AKT31.48537032
28CAMKK21.46639761
29PRPF4B1.46026576
30SGK2231.43398032
31SGK4941.43398032
32MAP3K61.43375049
33MKNK21.38358172
34RIPK41.37775904
35PNCK1.32024527
36PLK21.31838214
37MAPK131.29903394
38UHMK11.26409509
39PHKG11.25145422
40PHKG21.25145422
41GRK51.25031702
42KSR11.23674093
43MAP3K121.20897238
44STK381.19632728
45TRIM281.17577204
46STK38L1.13907644
47MAP3K21.13734452
48LMTK21.12715553
49YES11.11330011
50TYRO31.10959489
51MAP3K131.09687677
52TAOK31.09006789
53MKNK11.08833013
54PRKCH1.08400015
55FES1.05108541
56PRKCG1.04391395
57FGFR21.04081229
58CAMK2A1.00896732
59CSNK1G21.00125251
60DYRK30.98986996
61PINK10.96492099
62SGK20.95919853
63RET0.95400661
64STK110.92971710
65CAMK2B0.92731967
66SIK20.90749599
67ARAF0.90515678
68CAMK10.87520721
69DYRK1B0.86754797
70WNK40.84646079
71NEK60.84562755
72MAPKAPK50.84083652
73CDK180.83533815
74TNK20.83405917
75CDK150.82857301
76SGK30.82594311
77MAP4K20.81835272
78CDK140.81094848
79PKN10.80776073
80DAPK10.79286779
81SGK10.74664002
82PDK10.73794410
83DYRK1A0.73576373
84PAK30.72738055
85FGFR30.72603938
86PDPK10.71607495
87CSNK1A1L0.69866103
88DYRK20.69793661
89CAMK2D0.69032644
90CDK11A0.68832292
91ACVR1B0.68111703
92PTK2B0.67149442
93WNK30.66616689
94CAMK1G0.66178848
95MARK20.65820829
96CSNK1G30.64818330
97PRKCE0.63884302
98ROCK20.63567524
99CSNK1G10.62535982
100JAK20.59932984
101CDK30.58878462
102RPS6KA40.58179288
103CAMK2G0.57487843
104ALK0.55741016
105BCR0.55434812
106MAP3K70.55124018
107ERBB20.54977927
108CDC42BPA0.54657761
109RPS6KA30.54641529
110FYN0.53319064
111MAPK100.52152394
112NEK90.51967133
113TAOK20.51790616
114MUSK0.51694952
115MAP3K10.51332364
116INSRR0.50819473
117BMPR1B0.50683872
118SRPK10.48838661
119ICK0.48810210
120RIPK10.48605652
121LATS10.47047228
122BMPR20.46820717
123MAP3K50.46411117
124CSNK1D0.45346061
125CDK60.44721115
126FGFR10.44286561
127DMPK0.44228386
128PRKCZ0.43997517
129RAF10.42929205
130CAMK40.42370347
131FGR0.42021249
132MAPK70.41971320
133PDGFRB0.40395030
134PRKACB0.39586789
135OBSCN0.35934637
136PRKAA10.35367600
137PRKG10.35231960
138RPS6KB10.35191941

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.35713003
2Synaptic vesicle cycle_Homo sapiens_hsa047213.02890621
3GABAergic synapse_Homo sapiens_hsa047272.70877319
4Circadian entrainment_Homo sapiens_hsa047132.62376201
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.60828533
6Glutamatergic synapse_Homo sapiens_hsa047242.59957895
7Morphine addiction_Homo sapiens_hsa050322.48538398
8Olfactory transduction_Homo sapiens_hsa047402.47941413
9Long-term potentiation_Homo sapiens_hsa047202.41123622
10Amphetamine addiction_Homo sapiens_hsa050312.16191358
11Salivary secretion_Homo sapiens_hsa049702.12310256
12Dopaminergic synapse_Homo sapiens_hsa047282.08285282
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.07045546
14Insulin secretion_Homo sapiens_hsa049112.00313362
15Phototransduction_Homo sapiens_hsa047441.99521287
16Cholinergic synapse_Homo sapiens_hsa047251.90642536
17Long-term depression_Homo sapiens_hsa047301.85238342
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.81235439
19Gastric acid secretion_Homo sapiens_hsa049711.79390385
20Taste transduction_Homo sapiens_hsa047421.71119894
21Serotonergic synapse_Homo sapiens_hsa047261.70862437
22Renin secretion_Homo sapiens_hsa049241.68201578
23Cocaine addiction_Homo sapiens_hsa050301.65166606
24Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.60411571
25Oxytocin signaling pathway_Homo sapiens_hsa049211.53696038
26Calcium signaling pathway_Homo sapiens_hsa040201.49134843
27GnRH signaling pathway_Homo sapiens_hsa049121.40141846
28Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.38619410
29Gap junction_Homo sapiens_hsa045401.36878718
30Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.29782396
31cAMP signaling pathway_Homo sapiens_hsa040241.28704648
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.27576604
33Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23187131
34Collecting duct acid secretion_Homo sapiens_hsa049661.16688972
35Axon guidance_Homo sapiens_hsa043601.14661992
36Phosphatidylinositol signaling system_Homo sapiens_hsa040701.13030352
37Type II diabetes mellitus_Homo sapiens_hsa049301.11998311
38Dorso-ventral axis formation_Homo sapiens_hsa043201.08991882
39Fatty acid biosynthesis_Homo sapiens_hsa000611.06434283
40cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05630183
41Colorectal cancer_Homo sapiens_hsa052101.05207795
42Estrogen signaling pathway_Homo sapiens_hsa049151.02561962
43Nitrogen metabolism_Homo sapiens_hsa009101.02435758
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.02284291
45Vascular smooth muscle contraction_Homo sapiens_hsa042701.00032842
46Regulation of autophagy_Homo sapiens_hsa041400.99378589
47FoxO signaling pathway_Homo sapiens_hsa040680.97825799
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97681423
49Glioma_Homo sapiens_hsa052140.97468285
50Pancreatic secretion_Homo sapiens_hsa049720.96200482
51ErbB signaling pathway_Homo sapiens_hsa040120.96127444
52Melanogenesis_Homo sapiens_hsa049160.93555719
53Phospholipase D signaling pathway_Homo sapiens_hsa040720.93178105
54Cardiac muscle contraction_Homo sapiens_hsa042600.90538324
55Prolactin signaling pathway_Homo sapiens_hsa049170.88931731
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84287236
57Vibrio cholerae infection_Homo sapiens_hsa051100.83601035
58Dilated cardiomyopathy_Homo sapiens_hsa054140.83516349
59Thyroid hormone synthesis_Homo sapiens_hsa049180.75436171
60Choline metabolism in cancer_Homo sapiens_hsa052310.75185912
61MAPK signaling pathway_Homo sapiens_hsa040100.74978548
62Hedgehog signaling pathway_Homo sapiens_hsa043400.74741214
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.74062405
64Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.72954733
65Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70556892
66Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69371703
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.68393833
68Oocyte meiosis_Homo sapiens_hsa041140.66048242
69Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64896848
70Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.64810255
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.64605972
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64503503
73Circadian rhythm_Homo sapiens_hsa047100.62723032
74Sphingolipid signaling pathway_Homo sapiens_hsa040710.62395787
75Ras signaling pathway_Homo sapiens_hsa040140.62118126
76AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61369223
77SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60725639
78Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.60182603
79Renal cell carcinoma_Homo sapiens_hsa052110.58307593
80Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.56985279
81Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.56605427
82Rap1 signaling pathway_Homo sapiens_hsa040150.56485825
83Alcoholism_Homo sapiens_hsa050340.56012366
84Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.55395568
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.55346323
86Endocytosis_Homo sapiens_hsa041440.52562277
87T cell receptor signaling pathway_Homo sapiens_hsa046600.51240566
88Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51132452
89Hippo signaling pathway_Homo sapiens_hsa043900.50981472
90Ovarian steroidogenesis_Homo sapiens_hsa049130.50248511
91Inositol phosphate metabolism_Homo sapiens_hsa005620.50140832
92Wnt signaling pathway_Homo sapiens_hsa043100.49302335
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49286090
94VEGF signaling pathway_Homo sapiens_hsa043700.49222574
95NOD-like receptor signaling pathway_Homo sapiens_hsa046210.49136737
96Endometrial cancer_Homo sapiens_hsa052130.46046751
97Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.45571407
98Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.45430270
99mRNA surveillance pathway_Homo sapiens_hsa030150.45372538
100Non-homologous end-joining_Homo sapiens_hsa034500.45275422
101MicroRNAs in cancer_Homo sapiens_hsa052060.45129143
102Adherens junction_Homo sapiens_hsa045200.44443794
103Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.43726492
104Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.43107299
105mTOR signaling pathway_Homo sapiens_hsa041500.42861214
106Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.42740256
107Glucagon signaling pathway_Homo sapiens_hsa049220.42322831
108Bile secretion_Homo sapiens_hsa049760.39820602
109Osteoclast differentiation_Homo sapiens_hsa043800.39152181
110Non-small cell lung cancer_Homo sapiens_hsa052230.39020899
111Pancreatic cancer_Homo sapiens_hsa052120.38623917
112Jak-STAT signaling pathway_Homo sapiens_hsa046300.38397140
113Chemokine signaling pathway_Homo sapiens_hsa040620.37113699
114Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36208172
115Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.35663332
116Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.35461975
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.34893056
118Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.32450954
119Platelet activation_Homo sapiens_hsa046110.32399300
120Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31408439
121Insulin signaling pathway_Homo sapiens_hsa049100.31371088
122African trypanosomiasis_Homo sapiens_hsa051430.31338890
123Type I diabetes mellitus_Homo sapiens_hsa049400.30842333
124Ether lipid metabolism_Homo sapiens_hsa005650.30522402

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