ZDHHC19

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1axonemal dynein complex assembly (GO:0070286)9.68967260
2spermatid development (GO:0007286)9.64821474
3plasma membrane fusion (GO:0045026)9.62925985
4epithelial cilium movement (GO:0003351)9.49500909
5reproduction (GO:0000003)9.25026461
6cilium or flagellum-dependent cell motility (GO:0001539)9.00671928
7regulation of cilium movement (GO:0003352)8.95357703
8motile cilium assembly (GO:0044458)8.86987052
9response to pheromone (GO:0019236)8.53831683
10cilium movement (GO:0003341)7.86302923
11sperm capacitation (GO:0048240)7.44790553
12single fertilization (GO:0007338)7.30068022
13male meiosis (GO:0007140)7.12880808
14phosphatidylethanolamine biosynthetic process (GO:0006646)7.09079650
15epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)6.88735012
16piRNA metabolic process (GO:0034587)6.88227769
17synaptonemal complex organization (GO:0070193)6.68068811
18spermatogenesis (GO:0007283)6.64490250
19male gamete generation (GO:0048232)6.62479096
20microtubule depolymerization (GO:0007019)6.61752023
21organic cation transport (GO:0015695)6.61178364
22synaptonemal complex assembly (GO:0007130)6.58376730
23rRNA methylation (GO:0031167)6.51432819
24phosphatidylethanolamine metabolic process (GO:0046337)6.48315152
25negative regulation of inclusion body assembly (GO:0090084)6.12356820
26fertilization (GO:0009566)6.08877735
27gamete generation (GO:0007276)6.08296496
28protein targeting to Golgi (GO:0000042)5.93729742
29establishment of protein localization to Golgi (GO:0072600)5.65481574
30antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.63229370
31retrograde transport, vesicle recycling within Golgi (GO:0000301)5.53838101
32rRNA modification (GO:0000154)5.50782981
33calcium ion-dependent exocytosis (GO:0017156)5.50193969
34regulation of Rab GTPase activity (GO:0032313)5.48159910
35positive regulation of Rab GTPase activity (GO:0032851)5.48159910
36centriole replication (GO:0007099)5.39098871
37germ cell development (GO:0007281)5.36509152
38ventricular system development (GO:0021591)5.35154532
39cellular process involved in reproduction in multicellular organism (GO:0022412)5.31293104
40regulation of inclusion body assembly (GO:0090083)5.27667860
41chromosome condensation (GO:0030261)5.17515235
42regulation of microtubule-based movement (GO:0060632)5.15272323
43DNA packaging (GO:0006323)5.03283374
44microtubule severing (GO:0051013)4.99138395
45regulation of transcription involved in cell fate commitment (GO:0060850)4.97995744
46cell recognition (GO:0008037)4.96514069
47male meiosis I (GO:0007141)4.92970201
48chromosome organization involved in meiosis (GO:0070192)4.91026247
49spermatid nucleus differentiation (GO:0007289)4.89769997
50DNA methylation involved in gamete generation (GO:0043046)4.81673315
51cellular ketone body metabolic process (GO:0046950)4.79888905
52single strand break repair (GO:0000012)4.75028845
53multicellular organismal reproductive process (GO:0048609)4.73320012
54regulation of T-helper 2 cell differentiation (GO:0045628)4.54618442
55glycerol ether metabolic process (GO:0006662)4.37702458
56meiotic nuclear division (GO:0007126)4.21160934
57ketone body metabolic process (GO:1902224)4.18863413
58sequestering of actin monomers (GO:0042989)4.14814421
59protein localization to Golgi apparatus (GO:0034067)4.09875270
60regulation of centriole replication (GO:0046599)4.08842045
61ether metabolic process (GO:0018904)4.02725356
62left/right pattern formation (GO:0060972)4.01866856
63protein K11-linked deubiquitination (GO:0035871)3.97313647
64response to acidic pH (GO:0010447)3.94959521
65tooth mineralization (GO:0034505)3.91116020
66seminiferous tubule development (GO:0072520)3.89949606
67meiosis I (GO:0007127)3.88779234
68regulation of somitogenesis (GO:0014807)3.88482407
69multicellular organismal development (GO:0007275)3.86769949
70sexual reproduction (GO:0019953)3.75001377
71leukocyte migration involved in inflammatory response (GO:0002523)3.72242581
72synapsis (GO:0007129)3.69786885
73RNA destabilization (GO:0050779)3.63945125
74negative regulation of Rho protein signal transduction (GO:0035024)3.60827262
75peptidyl-threonine dephosphorylation (GO:0035970)3.58754576
76microtubule polymerization or depolymerization (GO:0031109)3.58202364
77protein localization to cilium (GO:0061512)3.57665605
78homeostasis of number of cells within a tissue (GO:0048873)3.55573289
79cerebral cortex neuron differentiation (GO:0021895)3.51819911
80protein polyglutamylation (GO:0018095)3.51531384
81protein-DNA complex disassembly (GO:0032986)3.50426776
82nucleosome disassembly (GO:0006337)3.50426776
83meiotic cell cycle (GO:0051321)3.47561091
84cellular response to pH (GO:0071467)3.42725701
85regulation of female gonad development (GO:2000194)3.42549795
86musculoskeletal movement (GO:0050881)3.42196660
87multicellular organismal movement (GO:0050879)3.42196660
88leukocyte aggregation (GO:0070486)3.37551751
89regulation of interleukin-13 production (GO:0032656)3.32427666
90regulation of spindle checkpoint (GO:0090231)3.31551104
91negative regulation of gene expression, epigenetic (GO:0045814)3.31370273
92Golgi to endosome transport (GO:0006895)3.29316010
93interferon-gamma secretion (GO:0072643)3.29075032
94chaperone-mediated protein complex assembly (GO:0051131)3.28790548
95positive regulation of type 2 immune response (GO:0002830)3.25606024
96coenzyme catabolic process (GO:0009109)3.25134439
97genitalia morphogenesis (GO:0035112)3.22012943
98membrane protein intracellular domain proteolysis (GO:0031293)3.21491222
99cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.15525374
100cilium organization (GO:0044782)3.13695566
101histone H3-K9 demethylation (GO:0033169)3.12807064
102nucleus organization (GO:0006997)3.05959891
103monoubiquitinated protein deubiquitination (GO:0035520)3.05344749
104negative regulation of skeletal muscle tissue development (GO:0048642)3.05013137
105cilium assembly (GO:0042384)3.04461937
106regulation of ARF GTPase activity (GO:0032312)2.97489756
107negative regulation of histone methylation (GO:0031061)2.97401818
108intraciliary transport (GO:0042073)2.95006627
109cellular component assembly involved in morphogenesis (GO:0010927)2.92477152
110peptide catabolic process (GO:0043171)2.90477604
111meiotic cell cycle process (GO:1903046)2.87765979
112positive regulation of macrophage activation (GO:0043032)2.85603740
113NAD biosynthetic process (GO:0009435)2.82366676
114glycolytic process (GO:0006096)2.80390554
115protein refolding (GO:0042026)2.80121438
116microtubule nucleation (GO:0007020)2.79620250
117cilium morphogenesis (GO:0060271)2.79405270
118mitotic G1 DNA damage checkpoint (GO:0031571)2.78277017
119DNA conformation change (GO:0071103)2.78066536
120regulation of phosphoprotein phosphatase activity (GO:0043666)2.77145192
121negative regulation of mesenchymal cell apoptotic process (GO:2001054)2.75221912
122nucleoside diphosphate phosphorylation (GO:0006165)2.73920052
123polyamine biosynthetic process (GO:0006596)2.71858921
124axoneme assembly (GO:0035082)2.69895312
125polyol catabolic process (GO:0046174)2.65780903
126negative regulation of organelle assembly (GO:1902116)2.58745196
127microtubule-based movement (GO:0007018)2.56001949
128centriole assembly (GO:0098534)2.52872101
129carnitine transport (GO:0015879)2.50955861
130amino-acid betaine transport (GO:0015838)2.50955861
131mitochondrion degradation (GO:0000422)2.46307074
132chromatin silencing (GO:0006342)2.41192296
133regulation of cytokine production involved in inflammatory response (GO:1900015)2.38048711
134peptidyl-glutamic acid modification (GO:0018200)2.36939615
135alditol metabolic process (GO:0019400)2.36593863
136carnitine transmembrane transport (GO:1902603)2.33330828
137histone exchange (GO:0043486)2.28369780
138GTP biosynthetic process (GO:0006183)2.27544204
139mitotic sister chromatid cohesion (GO:0007064)2.27072128
140fructose metabolic process (GO:0006000)2.22167914
141sperm motility (GO:0030317)13.5818695
142cell wall macromolecule metabolic process (GO:0044036)13.5438574
143cell wall macromolecule catabolic process (GO:0016998)13.5438574
144fusion of sperm to egg plasma membrane (GO:0007342)12.5153804
145acrosome reaction (GO:0007340)12.2127071
146sperm-egg recognition (GO:0035036)11.6003290
147acrosome assembly (GO:0001675)11.5118297
148multicellular organism reproduction (GO:0032504)10.8217648
149cell-cell recognition (GO:0009988)10.4562725
150binding of sperm to zona pellucida (GO:0007339)10.3829183

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.35363715
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.25099190
3TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.58357146
4EZH2_22144423_ChIP-Seq_EOC_Human3.84658752
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.76868094
6MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.75278630
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.32676657
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.89621343
9VDR_22108803_ChIP-Seq_LS180_Human2.77450452
10PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.70866954
11ELF1_20517297_ChIP-Seq_JURKAT_Human2.68299398
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.65594531
13VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.50927390
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.41751228
15* BCL6_27268052_Chip-Seq_Bcells_Human2.30611679
16PCGF2_27294783_Chip-Seq_ESCs_Mouse2.28919825
17LXR_22292898_ChIP-Seq_THP-1_Human2.26059552
18* EBNA2_21746931_ChIP-Seq_IB4-LCL_Human2.24394474
19* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human2.20119355
20ERA_21632823_ChIP-Seq_H3396_Human2.17673456
21P68_20966046_ChIP-Seq_HELA_Human2.15661516
22EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.15570453
23* GATA1_26923725_Chip-Seq_HPCs_Mouse2.15400606
24* BCOR_27268052_Chip-Seq_Bcells_Human2.14373486
25E2F1_20622854_ChIP-Seq_HELA_Human2.11302376
26NANOG_20526341_ChIP-Seq_ESCs_Human2.11070249
27RAC3_21632823_ChIP-Seq_H3396_Human2.08437043
28SMC4_20622854_ChIP-Seq_HELA_Human2.05539587
29YY1_22570637_ChIP-Seq_MALME-3M_Human2.04236268
30BP1_19119308_ChIP-ChIP_Hs578T_Human2.02992334
31PHF8_20622854_ChIP-Seq_HELA_Human2.00601355
32CTCF_27219007_Chip-Seq_Bcells_Human1.98235969
33DROSHA_22980978_ChIP-Seq_HELA_Human1.96949191
34STAT6_21828071_ChIP-Seq_BEAS2B_Human1.96790848
35CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.89747060
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.88358930
37CTCF_20526341_ChIP-Seq_ESCs_Human1.84436815
38PCGF2_27294783_Chip-Seq_NPCs_Mouse1.83391346
39STAT1_17558387_ChIP-Seq_HELA_Human1.78926276
40KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.78006736
41KAP1_22055183_ChIP-Seq_ESCs_Mouse1.73936454
42TAF2_19829295_ChIP-Seq_ESCs_Human1.72893372
43SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.71753049
44ELK4_26923725_Chip-Seq_MESODERM_Mouse1.71304045
45THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.71208304
46* P300_27268052_Chip-Seq_Bcells_Human1.70610035
47NFE2_27457419_Chip-Seq_LIVER_Mouse1.69869097
48* TAL1_26923725_Chip-Seq_HPCs_Mouse1.66390453
49TP63_22573176_ChIP-Seq_HFKS_Human1.63838848
50OCT4_20526341_ChIP-Seq_ESCs_Human1.63520283
51SUZ12_27294783_Chip-Seq_NPCs_Mouse1.62375657
52PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.59915594
53SA1_27219007_Chip-Seq_Bcells_Human1.59599239
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58802539
55GATA3_21867929_ChIP-Seq_CD8_Mouse1.58189350
56CBX2_27304074_Chip-Seq_ESCs_Mouse1.57374878
57* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.56018049
58TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.55644855
59* SOX2_22085726_ChIP-Seq_NPCs_Mouse1.51378193
60SA1_27219007_Chip-Seq_ERYTHROID_Human1.51262794
61TDRD3_21172665_ChIP-Seq_MCF-7_Human1.51184938
62KDM2B_26808549_Chip-Seq_REH_Human1.50319621
63WDR5_24793694_ChIP-Seq_LNCAP_Human1.49871096
64SPI1_20517297_ChIP-Seq_HL60_Human1.49558427
65RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.48401300
66FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48156012
67TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.48147536
68* P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.46822354
69ETV2_25802403_ChIP-Seq_MESCs_Mouse1.45848302
70ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.45278514
71PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.45239508
72ZNF274_21170338_ChIP-Seq_K562_Hela1.44084468
73RUNX_20019798_ChIP-Seq_JUKART_Human1.43975694
74CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43335329
75* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.40433440
76CEBPB_22108803_ChIP-Seq_LS180_Human1.39377292
77GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.38656646
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.36787430
79OCT4_18555785_Chip-Seq_ESCs_Mouse1.35885337
80AUTS2_25519132_ChIP-Seq_293T-REX_Human1.35176532
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.34797492
82CBP_20019798_ChIP-Seq_JUKART_Human1.34797492
83ZFP57_27257070_Chip-Seq_ESCs_Mouse1.33907100
84CRX_20693478_ChIP-Seq_RETINA_Mouse1.33188620
85GATA3_21867929_ChIP-Seq_TH1_Mouse1.31468116
86P53_22387025_ChIP-Seq_ESCs_Mouse1.30980476
87RBPJ_21746931_ChIP-Seq_IB4_Human1.30150622
88CMYC_18555785_Chip-Seq_ESCs_Mouse1.29316653
89OCT4_19829295_ChIP-Seq_ESCs_Human1.28710331
90KLF4_18555785_Chip-Seq_ESCs_Mouse1.28638532
91PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.28223125
92POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.25584701
93TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25584701
94EZH2_27294783_Chip-Seq_NPCs_Mouse1.25148742
95LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.24081278
96* GF1_26923725_Chip-Seq_HPCs_Mouse1.24011203
97FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.23964291
98CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23706308
99EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23151956
100HNFA_21074721_ChIP-Seq_CACO-2_Human1.22777685
101P300_18555785_Chip-Seq_ESCs_Mouse1.22262823
102STAT3_18555785_Chip-Seq_ESCs_Mouse1.21505200
103CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.21449546
104* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20977140
105SPI1_23127762_ChIP-Seq_K562_Human1.20001080
106ESRRB_18555785_Chip-Seq_ESCs_Mouse1.19926188
107CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.18927920
108SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.18917353
109UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.18815494
110STAT1_20625510_ChIP-Seq_HELA_Human1.18540754
111SPI1_26923725_Chip-Seq_HPCs_Mouse1.18470368
112GATA1_19941826_ChIP-Seq_K562_Human1.18284916
113CBX2_22325352_ChIP-Seq_293T-Rex_Human1.18230012
114SUZ12_18555785_Chip-Seq_ESCs_Mouse1.17512792
115GATA3_21878914_ChIP-Seq_MCF-7_Human1.17400473
116EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.17187905
117VDR_24787735_ChIP-Seq_THP-1_Human1.17180481
118FLI1_21867929_ChIP-Seq_TH2_Mouse1.16675207
119SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.16293486
120RNF2_27304074_Chip-Seq_NSC_Mouse1.15657677
121ETV1_20927104_ChIP-Seq_GIST48_Human1.15293837
122CTCF_21964334_Chip-Seq_Bcells_Human1.14609707
123DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.14251512
124* P53_21459846_ChIP-Seq_SAOS-2_Human1.13551842
125OCT4_21477851_ChIP-Seq_ESCs_Mouse1.13353019
126* SMRT_27268052_Chip-Seq_Bcells_Human1.13036561
127EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12948376
128PU1_27457419_Chip-Seq_LIVER_Mouse1.12208171
129E2F1_18555785_Chip-Seq_ESCs_Mouse1.12026434
130PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.11984166
131GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10834015
132BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human1.10743514
133SOX2_18555785_Chip-Seq_ESCs_Mouse1.10314334
134* KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.10230126
135TET1_21451524_ChIP-Seq_MESCs_Mouse1.10000717
136FOXH1_21741376_ChIP-Seq_ESCs_Human1.09927041
137PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09688864
138MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.09652466
139CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.09342341
140* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.09109937
141REST_21632747_ChIP-Seq_MESCs_Mouse1.09068141
142KLF4_19829295_ChIP-Seq_ESCs_Human1.08662460
143SMAD3_21741376_ChIP-Seq_ESCs_Human1.07510542
144ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.07096802
145* RAD21_21589869_ChIP-Seq_MESCs_Mouse1.06358209
146CTCF_18555785_Chip-Seq_ESCs_Mouse1.06342301
147GATA6_21074721_ChIP-Seq_CACO-2_Human1.06264175
148ESET_19884257_ChIP-Seq_ESCs_Mouse1.04751597
149LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse1.02688332
150NMYC_18555785_Chip-Seq_ESCs_Mouse1.02380348
151SUZ12_27294783_Chip-Seq_ESCs_Mouse1.01962123
152SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.01774215
153SMAD1_18555785_Chip-Seq_ESCs_Mouse1.01650826
154GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.01381728
155ZFX_18555785_Chip-Seq_ESCs_Mouse1.00480052
156CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00070780
157CSB_26484114_Chip-Seq_FIBROBLAST_Human0.99729713
158* RUNX1_26923725_Chip-Seq_HPCs_Mouse0.99445083
159RUNX1_27457419_Chip-Seq_LIVER_Mouse0.99419468
160RXRA_24833708_ChIP-Seq_LIVER_Mouse0.98059779
161* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.97129103
162* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.97060265
163ERG_20517297_ChIP-Seq_VCAP_Human0.96405572
164STAT3_18555785_ChIP-Seq_MESCs_Mouse0.96304759
165NFYB_21822215_ChIP-Seq_K562_Human0.96259543
166SOX11_22085726_ChIP-Seq_ESNs_Mouse0.95783229
167PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.95745391
168EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.95565736
169CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94952099
170MYC_19829295_ChIP-Seq_ESCs_Human0.94779386
171IKZF1_21737484_ChIP-ChIP_HCT116_Human0.93937588
172ARNT_22903824_ChIP-Seq_MCF-7_Human0.93566999
173PHF8_20622853_ChIP-Seq_HELA_Human0.93285932
174NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.93187893
175OCT1_27270436_Chip-Seq_PROSTATE_Human0.92882960
176MAF_26560356_Chip-Seq_TH2_Human0.92283008
177RUNX1_27514584_Chip-Seq_MCF-7_Human0.91904134

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.85378766
2MP0001929_abnormal_gametogenesis5.34820605
3MP0008877_abnormal_DNA_methylation3.78252267
4MP0002210_abnormal_sex_determination3.37078804
5MP0002161_abnormal_fertility/fecundity3.09769815
6MP0000678_abnormal_parathyroid_gland2.91822960
7MP0001145_abnormal_male_reproductive2.85668237
8MP0005670_abnormal_white_adipose2.51813765
9MP0000653_abnormal_sex_gland2.47585762
10MP0002160_abnormal_reproductive_system2.18858268
11MP0005410_abnormal_fertilization16.0907394
12MP0003718_maternal_effect1.91873959
13MP0002822_catalepsy1.91856791
14MP0003646_muscle_fatigue1.83952292
15MP0005310_abnormal_salivary_gland1.75418286
16MP0008058_abnormal_DNA_repair1.71711432
17MP0005623_abnormal_meninges_morphology1.63224605
18MP0002653_abnormal_ependyma_morphology1.57328090
19MP0002282_abnormal_trachea_morphology1.56915925
20MP0001485_abnormal_pinna_reflex1.40746788
21MP0002249_abnormal_larynx_morphology1.35965909
22MP0003436_decreased_susceptibility_to1.20429062
23MP0008995_early_reproductive_senescence1.20109207
24MP0009785_altered_susceptibility_to1.18681247
25MP0005389_reproductive_system_phenotype1.17783493
26MP0003724_increased_susceptibility_to1.14799940
27MP0002127_abnormal_cardiovascular_syste1.10732849
28MP0005647_abnormal_sex_gland1.08320636
29MP0002419_abnormal_innate_immunity1.06595631
30MP0009053_abnormal_anal_canal1.04812938
31MP0002163_abnormal_gland_morphology1.03206556
32MP0001486_abnormal_startle_reflex1.01290536
33MP0005423_abnormal_somatic_nervous0.99923169
34MP0004859_abnormal_synaptic_plasticity0.97316824
35MP0005025_abnormal_response_to0.95988387
36MP0001984_abnormal_olfaction0.95407291
37MP0003879_abnormal_hair_cell0.94303876
38MP0002735_abnormal_chemical_nociception0.91819178
39MP0005083_abnormal_biliary_tract0.91658481
40MP0010094_abnormal_chromosome_stability0.91512307
41MP0002132_abnormal_respiratory_system0.90615208
42MP0005395_other_phenotype0.89361270
43MP0005451_abnormal_body_composition0.89277245
44MP0008057_abnormal_DNA_replication0.86373698
45MP0001963_abnormal_hearing_physiology0.86079096
46MP0003115_abnormal_respiratory_system0.84786853
47MP0000569_abnormal_digit_pigmentation0.83151424
48MP0009697_abnormal_copulation0.82981994
49MP0009046_muscle_twitch0.82295285
50MP0009764_decreased_sensitivity_to0.81692930
51MP0001533_abnormal_skeleton_physiology0.79320035
52MP0003303_peritoneal_inflammation0.77532681
53MP0000681_abnormal_thyroid_gland0.77195073
54MP0004133_heterotaxia0.76706673
55MP0001293_anophthalmia0.73663711
56MP0003786_premature_aging0.73049851
57MP0002723_abnormal_immune_serum0.72853445
58MP0002229_neurodegeneration0.72243505
59MP0008569_lethality_at_weaning0.70904029
60MP0004233_abnormal_muscle_weight0.70522305
61MP0003111_abnormal_nucleus_morphology0.69103472
62MP0003787_abnormal_imprinting0.66144598
63MP0005375_adipose_tissue_phenotype0.65948473
64MP0001765_abnormal_ion_homeostasis0.64215061
65MP0001348_abnormal_lacrimal_gland0.63814629
66MP0009278_abnormal_bone_marrow0.63025543
67MP0001800_abnormal_humoral_immune0.62947189
68MP0005166_decreased_susceptibility_to0.61758794
69MP0005535_abnormal_body_temperature0.61004814
70MP0000026_abnormal_inner_ear0.60952142
71MP0005171_absent_coat_pigmentation0.60792169
72MP0002452_abnormal_antigen_presenting0.59981530
73MP0001873_stomach_inflammation0.59593500
74MP0001905_abnormal_dopamine_level0.59545491
75MP0005000_abnormal_immune_tolerance0.56986739
76MP0003077_abnormal_cell_cycle0.55613914
77MP0000955_abnormal_spinal_cord0.55488349
78MP0001835_abnormal_antigen_presentation0.55147075
79MP0008469_abnormal_protein_level0.54989743
80MP0001790_abnormal_immune_system0.54100812
81MP0005387_immune_system_phenotype0.54100812
82MP0002420_abnormal_adaptive_immunity0.54077927
83MP0002736_abnormal_nociception_after0.53916461
84MP0003828_pulmonary_edema0.53739847
85MP0005248_abnormal_Harderian_gland0.53733071
86MP0001819_abnormal_immune_cell0.53554924
87MP0000249_abnormal_blood_vessel0.52280184
88MP0004484_altered_response_of0.51928954
89MP0001119_abnormal_female_reproductive0.51882283
90MP0001666_abnormal_nutrient_absorption0.51192300
91MP0003172_abnormal_lysosome_physiology0.51012528
92MP0009765_abnormal_xenobiotic_induced0.50952529
93MP0003942_abnormal_urinary_system0.50733418
94MP0002102_abnormal_ear_morphology0.50580205
95MP0002928_abnormal_bile_duct0.50267742
96MP0002733_abnormal_thermal_nociception0.49816253
97MP0005084_abnormal_gallbladder_morpholo0.49537817
98MP0005319_abnormal_enzyme/_coenzyme0.49241177
99MP0005379_endocrine/exocrine_gland_phen0.48534399
100MP0006054_spinal_hemorrhage0.48294500
101MP0005167_abnormal_blood-brain_barrier0.47168527
102MP0000049_abnormal_middle_ear0.46757100
103MP0005367_renal/urinary_system_phenotyp0.46610069
104MP0000516_abnormal_urinary_system0.46610069
105MP0003878_abnormal_ear_physiology0.46473801
106MP0005377_hearing/vestibular/ear_phenot0.46473801
107MP0002067_abnormal_sensory_capabilities0.46245482
108MP0003011_delayed_dark_adaptation0.45737301
109MP0004134_abnormal_chest_morphology0.45315058
110MP0005253_abnormal_eye_physiology0.45171286
111MP0005397_hematopoietic_system_phenotyp0.43888881
112MP0001545_abnormal_hematopoietic_system0.43888881
113MP0002722_abnormal_immune_system0.43716969
114MP0005671_abnormal_response_to0.43707480
115MP0006082_CNS_inflammation0.43136111
116MP0010329_abnormal_lipoprotein_level0.42780740
117MP0001324_abnormal_eye_pigmentation0.41180955
118MP0000685_abnormal_immune_system0.41139692
119MP0002254_reproductive_system_inflammat0.41031629
120MP0001764_abnormal_homeostasis0.40202792
121MP0004036_abnormal_muscle_relaxation0.39558796
122MP0003699_abnormal_female_reproductive0.38857860
123MP0004019_abnormal_vitamin_homeostasis0.36810476
124MP0004742_abnormal_vestibular_system0.36523007
125MP0002405_respiratory_system_inflammati0.35974494
126MP0001346_abnormal_lacrimal_gland0.35678089
127MP0002269_muscular_atrophy0.35267901
128MP0000566_synostosis0.35243323
129MP0005636_abnormal_mineral_homeostasis0.35109359
130MP0001270_distended_abdomen0.28169799
131MP0003943_abnormal_hepatobiliary_system0.27761667
132MP0002295_abnormal_pulmonary_circulatio0.27570008
133MP0000372_irregular_coat_pigmentation0.26926670
134MP0002138_abnormal_hepatobiliary_system0.26331031
135MP0003283_abnormal_digestive_organ0.26240415
136MP0005391_vision/eye_phenotype0.26159829
137MP0000015_abnormal_ear_pigmentation0.26141399
138MP0003936_abnormal_reproductive_system0.25640551
139MP0005388_respiratory_system_phenotype0.25421227
140MP0002133_abnormal_respiratory_system0.25421227
141MP0002148_abnormal_hypersensitivity_rea0.25213028
142MP0001986_abnormal_taste_sensitivity0.24999946
143MP0004510_myositis0.24857243
144MP0002234_abnormal_pharynx_morphology0.24713778
145MP0005551_abnormal_eye_electrophysiolog0.24419340
146MP0005174_abnormal_tail_pigmentation0.22524582
147MP0000534_abnormal_ureter_morphology0.21581439
148MP0001502_abnormal_circadian_rhythm0.21543546
149MP0005666_abnormal_adipose_tissue0.21443085
150MP0006036_abnormal_mitochondrial_physio0.20929368
151MP0000462_abnormal_digestive_system0.20846720
152MP0009250_abnormal_appendicular_skeleto0.20696715
153MP0000313_abnormal_cell_death0.20164609
154MP0000537_abnormal_urethra_morphology0.19562079
155MP0009115_abnormal_fat_cell0.18908765
156MP0000920_abnormal_myelination0.18822548
157MP0000470_abnormal_stomach_morphology0.18788234
158MP0003948_abnormal_gas_homeostasis0.18320043
159MP0001968_abnormal_touch/_nociception0.18058970
160MP0008007_abnormal_cellular_replicative0.17590574

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)8.61491930
2Abnormal respiratory motile cilium morphology (HP:0005938)8.41353772
3Abnormal respiratory epithelium morphology (HP:0012253)8.41353772
4Severe visual impairment (HP:0001141)8.01774391
5Rhinitis (HP:0012384)7.04016648
6Abnormal ciliary motility (HP:0012262)6.84565722
7Infertility (HP:0000789)6.22883512
8Chronic bronchitis (HP:0004469)6.15575007
9Nasal polyposis (HP:0100582)5.60079718
10Asymmetric septal hypertrophy (HP:0001670)5.34108844
11Bony spicule pigmentary retinopathy (HP:0007737)4.93878271
12Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.84522567
13Nephronophthisis (HP:0000090)4.69126366
14Resting tremor (HP:0002322)4.52857173
15Attenuation of retinal blood vessels (HP:0007843)4.52322536
16Abnormality of the nasal mucosa (HP:0000433)4.44470907
17Male infertility (HP:0003251)4.12543109
18Bronchiectasis (HP:0002110)4.11167936
19Abnormal rod and cone electroretinograms (HP:0008323)4.09019297
20Bronchitis (HP:0012387)4.07161357
21Hyperkalemia (HP:0002153)3.98322470
22Facial shape deformation (HP:0011334)3.89887836
23Potter facies (HP:0002009)3.89887836
24Abnormal spermatogenesis (HP:0008669)3.85142991
25Aplasia/Hypoplasia of the earlobes (HP:0009906)3.61066826
26Abnormality of macular pigmentation (HP:0008002)3.58290803
27Abnormality of the renal medulla (HP:0100957)3.55268213
28Cone-rod dystrophy (HP:0000548)3.52360345
29Hypoplasia of the thymus (HP:0000778)3.42773258
30Hypoplastic ischia (HP:0003175)3.35885129
31Abnormality of the costochondral junction (HP:0000919)3.23056718
32Enlarged epiphyses (HP:0010580)3.20639427
33Osteomalacia (HP:0002749)3.20321311
34Postural instability (HP:0002172)3.19635878
35Tubulointerstitial nephritis (HP:0001970)3.18655649
36Recurrent otitis media (HP:0000403)2.98915423
37Recurrent sinusitis (HP:0011108)2.94364791
38Molar tooth sign on MRI (HP:0002419)2.88935953
39Abnormality of midbrain morphology (HP:0002418)2.88935953
40Hypoalphalipoproteinemia (HP:0003233)2.87035612
41Abnormality of the ischium (HP:0003174)2.85625020
42Impulsivity (HP:0100710)2.79955088
43Medial flaring of the eyebrow (HP:0010747)2.79180856
44Widely patent fontanelles and sutures (HP:0004492)2.78386625
45Recurrent pneumonia (HP:0006532)2.70742081
46Generalized aminoaciduria (HP:0002909)2.68579539
47Recurrent bronchitis (HP:0002837)2.68218923
48Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.64348638
49Tubular atrophy (HP:0000092)2.62448709
50Postaxial foot polydactyly (HP:0001830)2.62134200
51Abnormality of the aortic arch (HP:0012303)2.60720990
52Abnormal urine output (HP:0012590)2.60533283
53Amelogenesis imperfecta (HP:0000705)2.59798638
54Tubulointerstitial abnormality (HP:0001969)2.56881050
55Gingivitis (HP:0000230)2.56420149
56Tetany (HP:0001281)2.55133110
57Gastrointestinal infarctions (HP:0005244)2.51042310
58Abnormality of the parathyroid morphology (HP:0011766)2.50480633
59Progressive sensorineural hearing impairment (HP:0000408)2.49399475
60Azoospermia (HP:0000027)2.48162159
61Hypoplastic left heart (HP:0004383)2.47249660
62Unilateral renal agenesis (HP:0000122)2.46275825
63Obstructive lung disease (HP:0006536)2.40219381
64Chronic obstructive pulmonary disease (HP:0006510)2.40219381
65Truncal obesity (HP:0001956)2.38322041
66Pancreatic fibrosis (HP:0100732)2.36813730
67True hermaphroditism (HP:0010459)2.35465166
68Abnormality of macrophages (HP:0004311)2.35446091
69Hypochromic microcytic anemia (HP:0004840)2.31290018
70Decreased central vision (HP:0007663)2.31092358
71Portal hypertension (HP:0001409)2.27412975
72Double outlet right ventricle (HP:0001719)2.27233499
73Congenital malformation of the right heart (HP:0011723)2.27233499
74Epiphyseal dysplasia (HP:0002656)2.26753493
75Congenital hepatic fibrosis (HP:0002612)2.25037329
76Abnormality of dental color (HP:0011073)2.24657519
77Hypoplastic heart (HP:0001961)2.22455628
78Bile duct proliferation (HP:0001408)2.22169260
79Abnormal biliary tract physiology (HP:0012439)2.22169260
80Abnormality of potassium homeostasis (HP:0011042)2.21742715
81Recurrent abscess formation (HP:0002722)2.17840530
82Spastic paraparesis (HP:0002313)2.17270941
83Ventricular tachycardia (HP:0004756)2.16238625
84Dyschromatopsia (HP:0007641)2.12940433
85Abnormality of the renal cortex (HP:0011035)2.12606200
86Occipital encephalocele (HP:0002085)2.11573180
87Recurrent bacterial skin infections (HP:0005406)2.10781420
88Menstrual irregularities (HP:0000858)2.10772706
89Abnormality of the hepatic vasculature (HP:0006707)2.06536212
90Recurrent gram-negative bacterial infections (HP:0005420)2.05998434
91Hypoplasia of the capital femoral epiphysis (HP:0003090)2.05412954
92Hypophosphatemic rickets (HP:0004912)2.04586297
93Hyperthyroidism (HP:0000836)2.03027618
94Aplasia/Hypoplasia of the thymus (HP:0010515)2.03020597
95Vertebral clefting (HP:0008428)2.01947131
96Renal Fanconi syndrome (HP:0001994)2.01506080
97Spastic tetraparesis (HP:0001285)2.01498891
98Respiratory insufficiency due to defective ciliary clearance (HP:0200073)12.4764959
99Absent/shortened dynein arms (HP:0200106)12.0799397
100Dynein arm defect of respiratory motile cilia (HP:0012255)12.0799397
101Tubulointerstitial fibrosis (HP:0005576)1.99679551
102Aplasia/Hypoplasia of the sacrum (HP:0008517)1.97500104
103Progressive cerebellar ataxia (HP:0002073)1.97253635
104Absent epiphyses (HP:0010577)1.96417141
105Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.96417141
106Polyuria (HP:0000103)1.95085291
107Renal dysplasia (HP:0000110)1.91709406
108Cerebellar dysplasia (HP:0007033)1.91276632
109Hyponatremia (HP:0002902)1.91011315
110Flattened epiphyses (HP:0003071)1.90772775
111Cholecystitis (HP:0001082)1.87812117
112Abnormal gallbladder physiology (HP:0012438)1.87812117
113Peripheral hypomyelination (HP:0007182)1.87344007
114Peritonitis (HP:0002586)1.86850989
115Cystic liver disease (HP:0006706)1.86786745
116Insulin-resistant diabetes mellitus (HP:0000831)1.86123736
117Gonadotropin excess (HP:0000837)1.86024189
118Facial cleft (HP:0002006)1.83255170
119Stage 5 chronic kidney disease (HP:0003774)1.81039628
120Abnormal drinking behavior (HP:0030082)1.80087867
121Polydipsia (HP:0001959)1.80087867
122Eczematoid dermatitis (HP:0000976)1.79709910
123Postaxial hand polydactyly (HP:0001162)1.79636193
124Bowel incontinence (HP:0002607)1.79086433
125Abnormality of dentin (HP:0010299)1.78143696
126Fibular hypoplasia (HP:0003038)1.74902341
127Abnormal ventriculo-arterial connection (HP:0011563)1.74390122
128Transposition of the great arteries (HP:0001669)1.74390122
129Abnormal connection of the cardiac segments (HP:0011545)1.74390122
130Choroideremia (HP:0001139)1.66415592
131Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.66140111
132Short ribs (HP:0000773)1.65943443
133Abnormality of renal excretion (HP:0011036)1.63925028
134Taurodontia (HP:0000679)1.63190145
135Abnormality of permanent molar morphology (HP:0011071)1.63190145
136Abnormality of the dental root (HP:0006486)1.63190145
137Pancreatic cysts (HP:0001737)1.62528877
138Abnormality of the dental pulp (HP:0006479)1.58537534
139Absent frontal sinuses (HP:0002688)1.57738918
140Aplasia/Hypoplasia of the tongue (HP:0010295)1.57391006
141Optic nerve hypoplasia (HP:0000609)1.55599646
142Abnormality of molar morphology (HP:0011070)1.55096194
143Abnormality of molar (HP:0011077)1.55096194
144Bell-shaped thorax (HP:0001591)1.54980890
145Congenital primary aphakia (HP:0007707)1.54880263
146Oculomotor apraxia (HP:0000657)1.54346864
147Short thorax (HP:0010306)1.53899165
148Aplasia/Hypoplasia of the lens (HP:0008063)1.51993803
149Chronic hepatic failure (HP:0100626)1.51983145
150Retinal dysplasia (HP:0007973)1.51552907
151Gait imbalance (HP:0002141)1.50718094
152Retinal atrophy (HP:0001105)1.50327634
153Nephroblastoma (Wilms tumor) (HP:0002667)1.50055953
154Nephropathy (HP:0000112)1.49273407
155Supernumerary spleens (HP:0009799)1.48899026
156Broad distal phalanx of finger (HP:0009836)1.48484080
157Pachygyria (HP:0001302)1.45199197
158Lissencephaly (HP:0001339)1.44956786
159Decreased electroretinogram (ERG) amplitude (HP:0000654)1.44301207
160Median cleft lip (HP:0000161)1.42569415
161Hemorrhage of the eye (HP:0011885)1.41633309
162Vaginal atresia (HP:0000148)1.40421821
163Preaxial hand polydactyly (HP:0001177)1.36722062
164Easy fatigability (HP:0003388)1.36524197
165Embryonal renal neoplasm (HP:0011794)1.36449484
166Genital tract atresia (HP:0001827)1.36193129
167Neurofibrillary tangles (HP:0002185)1.34074317

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK37.34228438
2PDK47.34228438
3TESK16.94620880
4PRKD35.13359586
5DDR24.76753957
6PDK24.70783136
7ICK4.20849281
8PLK22.50277389
9PTK2B2.46509969
10INSRR2.43422866
11STK392.42195434
12WNK42.35214505
13BRD42.18183564
14MAP4K22.18027552
15CAMK1G2.13510450
16STK381.84862432
17MAP3K111.73689306
18STK38L1.66847004
19PNCK1.65197137
20KSR21.47699352
21NEK21.46919965
22CDK71.44276914
23TESK21.39819628
24DYRK31.25070791
25DYRK1B1.18877894
26SIK21.18395822
27MST1R1.15508967
28JAK31.03374461
29CDK121.01874341
30BLK0.94054937
31MAP3K10.92600477
32RPS6KA20.91205197
33GRK60.89777893
34PDK10.89386530
35TTK0.88207185
36STK30.86978681
37WNK10.83823063
38MAP3K80.83327849
39RPS6KA10.80724385
40PINK10.80414491
41MAPKAPK50.80153360
42CSK0.79977698
43CAMK1D0.77966965
44CHEK20.74195137
45IRAK40.71693124
46PASK0.69198311
47MAP3K20.68752018
48RPS6KC10.68175164
49RPS6KL10.68175164
50MAP3K30.65729937
51MAP2K20.62190478
52UHMK10.61733477
53IRAK10.60937383
54PRKAA20.58594602
55CDK40.58354253
56CASK0.58236310
57MAP2K60.58079591
58RPS6KA60.58070960
59NEK60.57646424
60LMTK20.56777972
61ERN10.56302735
62EEF2K0.55234305
63CDK190.54773536
64MAP2K30.54632021
65WEE10.54221873
66STK240.53211886
67MAPK150.53198707
68CAMK10.52477137
69ATR0.51395526
70ZAK0.49623061
71ROCK10.48808181
72MAP3K90.48747186
73PAK40.48440775
74STK160.47278642
75PRKCG0.46406930
76CCNB10.46005294
77ADRBK20.44272911
78FES0.43551681
79CDK20.43430106
80MAPK10.43096661
81PBK0.42981232
82JAK20.41278215
83BRSK20.40579822
84MAP3K140.39717261
85PDPK10.37821578
86GSK3B0.37778559
87MAP2K70.37244204
88PAK10.37135358
89CDC70.35602102
90OBSCN0.35537962
91PLK40.35371059
92CHEK10.34689447
93MAPK80.33891810
94PRKG20.33145286
95HCK0.33106918
96SYK0.33010618
97CDK10.32993610
98YES10.32039440
99RPS6KB10.31862739
100ACVR1B0.31416143
101ATM0.30894511
102CSF1R0.30229855
103IRAK20.30160679
104SGK10.30011723
105PLK10.29858066
106WNK30.29821262
107BTK0.29027649
108FGR0.28708799
109MYLK0.28576082
110PIM10.28227596
111RIPK40.27697439
112RIPK10.27501163
113IKBKB0.27365451
114ARAF0.25209483
115MUSK0.25177177
116CAMK40.25167810
117BRSK10.24762053
118PRKCQ0.23906427
119PRKCB0.23332694
120MTOR0.23056971
121SGK20.22807446
122KIT0.22802302
123CSNK2A10.22323506
124SRPK10.21612318
125NTRK20.20697077
126TAOK10.20634046
127CDK30.20084727
128IKBKE0.19797290
129TXK0.19116825
130TYRO30.18927462
131MAPK140.18681974
132GRK10.18605711
133LYN0.18577570
134BRAF0.18514022
135OXSR10.18344094
136TNIK0.18173325
137MARK30.17665334
138LATS20.17497987
139MARK10.16853904
140PAK20.16145291
141PIK3CG0.16138150
142AKT30.16079481
143MAPK100.16062016
144AKT10.16005882
145MAPK110.15867228
146EIF2AK20.15206044
147SGK4940.14862797
148SGK2230.14862797
149TAF10.14797184
150CAMK2A0.14758733
151BMPR20.13891729
152PRKCZ0.13476964
153MAP3K70.13187434
154CLK10.13168690
155MINK10.12563362
156PRKG10.12430102
157MARK20.11847274
158PRKD20.09925790
159TNK20.09904540
160PRKCD0.09466393
161PRKAA10.08030367
162BMPR1B0.07509665
163MAP4K10.07259744
164PKN10.06987551
165ZAP700.06931482
166PRKACG0.06521259
167PRKACA0.05999865

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000726.70753342
2Fatty acid biosynthesis_Homo sapiens_hsa000614.10934090
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.83202141
4Linoleic acid metabolism_Homo sapiens_hsa005913.59350297
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.55052414
6Olfactory transduction_Homo sapiens_hsa047402.94805446
7Pyruvate metabolism_Homo sapiens_hsa006202.88874504
8Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.86020629
9Vitamin B6 metabolism_Homo sapiens_hsa007502.86016543
10Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.62802383
11Basal transcription factors_Homo sapiens_hsa030222.58798805
12Fanconi anemia pathway_Homo sapiens_hsa034602.50862416
13Selenocompound metabolism_Homo sapiens_hsa004502.49716943
14Propanoate metabolism_Homo sapiens_hsa006402.05656133
15Ether lipid metabolism_Homo sapiens_hsa005651.98740478
16Type I diabetes mellitus_Homo sapiens_hsa049401.89389238
17Glucagon signaling pathway_Homo sapiens_hsa049221.86804131
18Carbohydrate digestion and absorption_Homo sapiens_hsa049731.86539414
19Butanoate metabolism_Homo sapiens_hsa006501.86245574
20Type II diabetes mellitus_Homo sapiens_hsa049301.75426981
21Fructose and mannose metabolism_Homo sapiens_hsa000511.72791868
22Glycerophospholipid metabolism_Homo sapiens_hsa005641.71469713
23Arachidonic acid metabolism_Homo sapiens_hsa005901.69065435
24Pentose phosphate pathway_Homo sapiens_hsa000301.66810398
25Purine metabolism_Homo sapiens_hsa002301.64562812
26Mineral absorption_Homo sapiens_hsa049781.61370361
27Huntingtons disease_Homo sapiens_hsa050161.58674806
28Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.53569784
29Glutathione metabolism_Homo sapiens_hsa004801.53535573
30Glycerolipid metabolism_Homo sapiens_hsa005611.53148829
31Collecting duct acid secretion_Homo sapiens_hsa049661.51937354
32Viral myocarditis_Homo sapiens_hsa054161.50099583
33Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.49785942
34Osteoclast differentiation_Homo sapiens_hsa043801.41589974
35Leishmaniasis_Homo sapiens_hsa051401.38189290
36Cardiac muscle contraction_Homo sapiens_hsa042601.35138209
37Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.34549214
38Acute myeloid leukemia_Homo sapiens_hsa052211.29850452
39Oocyte meiosis_Homo sapiens_hsa041141.27434844
40Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.21579145
41PPAR signaling pathway_Homo sapiens_hsa033201.18164777
42Fat digestion and absorption_Homo sapiens_hsa049751.15930923
43Staphylococcus aureus infection_Homo sapiens_hsa051501.15179378
44Dorso-ventral axis formation_Homo sapiens_hsa043201.14976900
45Influenza A_Homo sapiens_hsa051641.14801742
46Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.13134906
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.11989254
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.10931974
49Pyrimidine metabolism_Homo sapiens_hsa002401.09013413
50Amphetamine addiction_Homo sapiens_hsa050311.07585933
51Proteasome_Homo sapiens_hsa030501.06752210
52Taste transduction_Homo sapiens_hsa047421.05053798
53Phenylalanine metabolism_Homo sapiens_hsa003601.04888614
54B cell receptor signaling pathway_Homo sapiens_hsa046621.04057509
55Antigen processing and presentation_Homo sapiens_hsa046121.01138411
56Sulfur metabolism_Homo sapiens_hsa009200.99033634
57Fatty acid metabolism_Homo sapiens_hsa012120.97502027
58Glycosaminoglycan degradation_Homo sapiens_hsa005310.96936808
59Renin secretion_Homo sapiens_hsa049240.93672356
60Carbon metabolism_Homo sapiens_hsa012000.93382466
61Hedgehog signaling pathway_Homo sapiens_hsa043400.90334368
62Autoimmune thyroid disease_Homo sapiens_hsa053200.85869213
63Legionellosis_Homo sapiens_hsa051340.84595771
64Fatty acid degradation_Homo sapiens_hsa000710.84522455
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.82770465
66Homologous recombination_Homo sapiens_hsa034400.82387839
67Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.78361989
68Chemical carcinogenesis_Homo sapiens_hsa052040.77763012
69DNA replication_Homo sapiens_hsa030300.75957013
70Chemokine signaling pathway_Homo sapiens_hsa040620.75415589
71Arginine and proline metabolism_Homo sapiens_hsa003300.73586502
72Renin-angiotensin system_Homo sapiens_hsa046140.69723825
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.69658979
74RNA transport_Homo sapiens_hsa030130.68807988
75Herpes simplex infection_Homo sapiens_hsa051680.68175868
76Systemic lupus erythematosus_Homo sapiens_hsa053220.67638686
77Protein digestion and absorption_Homo sapiens_hsa049740.65743226
78Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.64883613
79Base excision repair_Homo sapiens_hsa034100.63553615
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.62798231
81Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62390906
82Jak-STAT signaling pathway_Homo sapiens_hsa046300.60175676
83mRNA surveillance pathway_Homo sapiens_hsa030150.59551339
84Metabolic pathways_Homo sapiens_hsa011000.58821932
85Morphine addiction_Homo sapiens_hsa050320.58110310
86Primary bile acid biosynthesis_Homo sapiens_hsa001200.57250513
87Intestinal immune network for IgA production_Homo sapiens_hsa046720.57204974
88Sphingolipid metabolism_Homo sapiens_hsa006000.56552454
89Tuberculosis_Homo sapiens_hsa051520.56051271
90Allograft rejection_Homo sapiens_hsa053300.55100409
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.54991195
92VEGF signaling pathway_Homo sapiens_hsa043700.54913231
93ABC transporters_Homo sapiens_hsa020100.54850999
94Oxidative phosphorylation_Homo sapiens_hsa001900.53816073
95Toxoplasmosis_Homo sapiens_hsa051450.53309207
96Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51886858
97Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.50458637
98MAPK signaling pathway_Homo sapiens_hsa040100.50106340
99Biosynthesis of amino acids_Homo sapiens_hsa012300.48254256
100Arginine biosynthesis_Homo sapiens_hsa002200.47484613
101Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.47108414
102cAMP signaling pathway_Homo sapiens_hsa040240.45841768
103Viral carcinogenesis_Homo sapiens_hsa052030.45284761
104Graft-versus-host disease_Homo sapiens_hsa053320.43930827
105Parkinsons disease_Homo sapiens_hsa050120.43367724
106Inositol phosphate metabolism_Homo sapiens_hsa005620.42832530
107Histidine metabolism_Homo sapiens_hsa003400.42345651
108Measles_Homo sapiens_hsa051620.41762083
109Estrogen signaling pathway_Homo sapiens_hsa049150.41229356
110Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.40847989
111Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40583658
112cGMP-PKG signaling pathway_Homo sapiens_hsa040220.40329365
113Vascular smooth muscle contraction_Homo sapiens_hsa042700.39202135
114Rheumatoid arthritis_Homo sapiens_hsa053230.38777773
115Prolactin signaling pathway_Homo sapiens_hsa049170.37908434
116Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.37028438
117Nucleotide excision repair_Homo sapiens_hsa034200.36931208
118Salivary secretion_Homo sapiens_hsa049700.36642235
119Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.36037416
120Synaptic vesicle cycle_Homo sapiens_hsa047210.35901001
121Epstein-Barr virus infection_Homo sapiens_hsa051690.35166694
122Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.34924436
123Cell cycle_Homo sapiens_hsa041100.34667193
124Malaria_Homo sapiens_hsa051440.34271991
125Gastric acid secretion_Homo sapiens_hsa049710.34081498
126Adipocytokine signaling pathway_Homo sapiens_hsa049200.33511263
127Alcoholism_Homo sapiens_hsa050340.33450089
128Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.33251367
129Hematopoietic cell lineage_Homo sapiens_hsa046400.32448833
130Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31812155
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30981813
132Vitamin digestion and absorption_Homo sapiens_hsa049770.30617949
133Thyroid hormone synthesis_Homo sapiens_hsa049180.30202461
134Tyrosine metabolism_Homo sapiens_hsa003500.30023452
135HIF-1 signaling pathway_Homo sapiens_hsa040660.30001513
136Non-homologous end-joining_Homo sapiens_hsa034500.29754049
137Phototransduction_Homo sapiens_hsa047440.29033978
138Basal cell carcinoma_Homo sapiens_hsa052170.28654782
139Insulin secretion_Homo sapiens_hsa049110.28611659
140Circadian entrainment_Homo sapiens_hsa047130.27849304
141Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.27082847
142Calcium signaling pathway_Homo sapiens_hsa040200.26062311
143Endocytosis_Homo sapiens_hsa041440.24402199
144RNA degradation_Homo sapiens_hsa030180.24087812
145Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.23293541
146RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.22947179
147Retinol metabolism_Homo sapiens_hsa008300.22353379
148Steroid biosynthesis_Homo sapiens_hsa001000.22279275
149Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.20925926
150Platelet activation_Homo sapiens_hsa046110.20031278
151Insulin signaling pathway_Homo sapiens_hsa049100.19904610
152Sphingolipid signaling pathway_Homo sapiens_hsa040710.19761822
153Toll-like receptor signaling pathway_Homo sapiens_hsa046200.18997138
154Insulin resistance_Homo sapiens_hsa049310.18955916
155Pentose and glucuronate interconversions_Homo sapiens_hsa000400.17545928
156Phagosome_Homo sapiens_hsa041450.17521452
157Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.16419010
158Primary immunodeficiency_Homo sapiens_hsa053400.15780735
159Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.15434541

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