

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of protein glycosylation (GO:0060049) | 9.08262211 |
| 2 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.64816524 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.64389237 |
| 4 | detection of molecule of bacterial origin (GO:0032490) | 5.20537491 |
| 5 | sphingosine metabolic process (GO:0006670) | 5.04705047 |
| 6 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.84957178 |
| 7 | microglial cell activation (GO:0001774) | 4.62236846 |
| 8 | B cell proliferation (GO:0042100) | 4.51088015 |
| 9 | diol metabolic process (GO:0034311) | 4.45379535 |
| 10 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.43207958 |
| 11 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.39929987 |
| 12 | regulation of gamma-delta T cell activation (GO:0046643) | 4.37785384 |
| 13 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.34699215 |
| 14 | negative regulation of cell killing (GO:0031342) | 4.34699215 |
| 15 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.26406144 |
| 16 | B cell receptor signaling pathway (GO:0050853) | 4.16189551 |
| 17 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.08686378 |
| 18 | modulation by symbiont of host immune response (GO:0052553) | 4.08686378 |
| 19 | positive regulation by symbiont of host defense response (GO:0052509) | 4.08686378 |
| 20 | modulation by symbiont of host defense response (GO:0052031) | 4.08686378 |
| 21 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.08686378 |
| 22 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.08686378 |
| 23 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 3.96511816 |
| 24 | positive regulation of interferon-alpha production (GO:0032727) | 3.95890894 |
| 25 | sphingoid metabolic process (GO:0046519) | 3.94576115 |
| 26 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 3.91271171 |
| 27 | regulation of interferon-alpha production (GO:0032647) | 3.87636809 |
| 28 | regulation of histone H3-K27 methylation (GO:0061085) | 3.83458521 |
| 29 | regulation of glycoprotein biosynthetic process (GO:0010559) | 3.80952059 |
| 30 | macrophage activation involved in immune response (GO:0002281) | 3.77837801 |
| 31 | detection of external biotic stimulus (GO:0098581) | 3.72157811 |
| 32 | response to type I interferon (GO:0034340) | 3.71574225 |
| 33 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.67749139 |
| 34 | cellular response to type I interferon (GO:0071357) | 3.67516608 |
| 35 | type I interferon signaling pathway (GO:0060337) | 3.67516608 |
| 36 | peptidyl-lysine trimethylation (GO:0018023) | 3.61720784 |
| 37 | negative regulation of B cell proliferation (GO:0030889) | 3.53505239 |
| 38 | hepatocyte apoptotic process (GO:0097284) | 3.52412609 |
| 39 | cellular response to ethanol (GO:0071361) | 3.48834869 |
| 40 | macrophage activation (GO:0042116) | 3.43708659 |
| 41 | negative regulation of T cell mediated immunity (GO:0002710) | 3.42382532 |
| 42 | negative T cell selection (GO:0043383) | 3.42077829 |
| 43 | cellular response to virus (GO:0098586) | 3.41122818 |
| 44 | negative thymic T cell selection (GO:0045060) | 3.38849951 |
| 45 | myeloid leukocyte mediated immunity (GO:0002444) | 3.37711930 |
| 46 | neutrophil mediated immunity (GO:0002446) | 3.37034952 |
| 47 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.34202634 |
| 48 | positive thymic T cell selection (GO:0045059) | 3.30793153 |
| 49 | negative regulation of interleukin-12 production (GO:0032695) | 3.24761147 |
| 50 | detection of biotic stimulus (GO:0009595) | 3.24593136 |
| 51 | positive T cell selection (GO:0043368) | 3.24117182 |
| 52 | regulation of pigment cell differentiation (GO:0050932) | 3.23744561 |
| 53 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.21453940 |
| 54 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.20125527 |
| 55 | histone H3-K36 demethylation (GO:0070544) | 3.17934040 |
| 56 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.17777607 |
| 57 | response to host immune response (GO:0052572) | 3.17777607 |
| 58 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.16071019 |
| 59 | embryonic process involved in female pregnancy (GO:0060136) | 3.12543584 |
| 60 | positive regulation of developmental pigmentation (GO:0048087) | 3.12069381 |
| 61 | positive regulation of interferon-beta production (GO:0032728) | 3.11523321 |
| 62 | germinal center formation (GO:0002467) | 3.10611726 |
| 63 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.05400376 |
| 64 | necrotic cell death (GO:0070265) | 3.05091737 |
| 65 | negative regulation of complement activation (GO:0045916) | 3.04794277 |
| 66 | histone H3-K9 modification (GO:0061647) | 3.04456371 |
| 67 | detection of other organism (GO:0098543) | 3.03640747 |
| 68 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.03229341 |
| 69 | mature B cell differentiation (GO:0002335) | 3.02253491 |
| 70 | regulation of glycoprotein metabolic process (GO:1903018) | 3.01563751 |
| 71 | lymphocyte proliferation (GO:0046651) | 3.01431265 |
| 72 | regulation of necroptotic process (GO:0060544) | 3.00345399 |
| 73 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.98890071 |
| 74 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.98813153 |
| 75 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.98741495 |
| 76 | negative regulation of B cell mediated immunity (GO:0002713) | 2.98741495 |
| 77 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.98538404 |
| 78 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.95577313 |
| 79 | T cell proliferation (GO:0042098) | 2.95346665 |
| 80 | mononuclear cell proliferation (GO:0032943) | 2.93020449 |
| 81 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.90197470 |
| 82 | negative regulation of glycoprotein metabolic process (GO:1903019) | 2.88752098 |
| 83 | positive regulation of humoral immune response (GO:0002922) | 2.86057715 |
| 84 | histone mRNA catabolic process (GO:0071044) | 2.85955217 |
| 85 | response to host (GO:0075136) | 2.85913985 |
| 86 | response to host defenses (GO:0052200) | 2.85913985 |
| 87 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.85913985 |
| 88 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.84802589 |
| 89 | response to interferon-alpha (GO:0035455) | 2.83939113 |
| 90 | programmed necrotic cell death (GO:0097300) | 2.83343126 |
| 91 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 2.81648622 |
| 92 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 2.81648622 |
| 93 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.81319577 |
| 94 | defense response to protozoan (GO:0042832) | 2.81283636 |
| 95 | regulation of regulatory T cell differentiation (GO:0045589) | 2.80780031 |
| 96 | regulation of odontogenesis of dentin-containing tooth (GO:0042487) | 2.79959173 |
| 97 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.79573926 |
| 98 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.79042743 |
| 99 | negative regulation of adaptive immune response (GO:0002820) | 2.76433793 |
| 100 | protein K11-linked deubiquitination (GO:0035871) | 2.74294105 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.72088063 |
| 2 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 5.90634564 |
| 3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.86438029 |
| 4 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.54005307 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.41745150 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.90271384 |
| 7 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.75171575 |
| 8 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.57578353 |
| 9 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.49191685 |
| 10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.46506248 |
| 11 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.44339183 |
| 12 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.36928914 |
| 13 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.22141682 |
| 14 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.17541524 |
| 15 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.17511954 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.16355165 |
| 17 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.08722307 |
| 18 | MYB_26560356_Chip-Seq_TH2_Human | 1.87076358 |
| 19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.83145729 |
| 20 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.79638610 |
| 21 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.79638610 |
| 22 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.71716269 |
| 23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.69500188 |
| 24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.68462097 |
| 25 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.65934424 |
| 26 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.62250264 |
| 27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.59743414 |
| 28 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.58465325 |
| 29 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.55074652 |
| 30 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.51705588 |
| 31 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.51445451 |
| 32 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.50737695 |
| 33 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.50489943 |
| 34 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.49995698 |
| 35 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.48679524 |
| 36 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.48019889 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.40435738 |
| 38 | GATA3_26560356_Chip-Seq_TH2_Human | 1.39997775 |
| 39 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.39314457 |
| 40 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.39203583 |
| 41 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.36640944 |
| 42 | GATA1_22025678_ChIP-Seq_K562_Human | 1.35372404 |
| 43 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.31883394 |
| 44 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.27954945 |
| 45 | MYB_26560356_Chip-Seq_TH1_Human | 1.27075525 |
| 46 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.24507832 |
| 47 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.23092240 |
| 48 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.22846358 |
| 49 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.22812471 |
| 50 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.21499215 |
| 51 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.19169131 |
| 52 | P300_19829295_ChIP-Seq_ESCs_Human | 1.17479095 |
| 53 | SPI1_23127762_ChIP-Seq_K562_Human | 1.16750342 |
| 54 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.15696601 |
| 55 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.15533132 |
| 56 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.14210104 |
| 57 | TP53_16413492_ChIP-PET_HCT116_Human | 1.14127459 |
| 58 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.11893545 |
| 59 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.11891820 |
| 60 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.11658957 |
| 61 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.10111607 |
| 62 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.09997277 |
| 63 | TCF4_23295773_ChIP-Seq_U87_Human | 1.09283828 |
| 64 | STAT3_23295773_ChIP-Seq_U87_Human | 1.08997878 |
| 65 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.08382298 |
| 66 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.07202737 |
| 67 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.06811485 |
| 68 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.06719811 |
| 69 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.06669709 |
| 70 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.05096722 |
| 71 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.05096722 |
| 72 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.04801283 |
| 73 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.04787474 |
| 74 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.04513272 |
| 75 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.04334306 |
| 76 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.03530961 |
| 77 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.02890769 |
| 78 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.00913640 |
| 79 | GATA2_19941826_ChIP-Seq_K562_Human | 0.99084723 |
| 80 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94675113 |
| 81 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94417929 |
| 82 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.93578229 |
| 83 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.93153353 |
| 84 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.92869919 |
| 85 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.92569051 |
| 86 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.92068088 |
| 87 | GATA3_26560356_Chip-Seq_TH1_Human | 0.91667308 |
| 88 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.90277713 |
| 89 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.89788272 |
| 90 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.89760581 |
| 91 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.89638579 |
| 92 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89300756 |
| 93 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88498107 |
| 94 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.86118497 |
| 95 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.85662969 |
| 96 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.84453177 |
| 97 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.84036504 |
| 98 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.83947481 |
| 99 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.83638771 |
| 100 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.83132917 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000569_abnormal_digit_pigmentation | 6.79223624 |
| 2 | MP0003787_abnormal_imprinting | 3.51729032 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.31031208 |
| 4 | MP0002837_dystrophic_cardiac_calcinosis | 3.25726499 |
| 5 | MP0003724_increased_susceptibility_to | 3.14428380 |
| 6 | MP0004381_abnormal_hair_follicle | 3.11016049 |
| 7 | MP0008260_abnormal_autophagy | 3.08607824 |
| 8 | MP0002653_abnormal_ependyma_morphology | 2.94171578 |
| 9 | MP0005171_absent_coat_pigmentation | 2.66335881 |
| 10 | MP0001800_abnormal_humoral_immune | 2.60540232 |
| 11 | MP0003045_fibrosis | 2.57559129 |
| 12 | MP0008057_abnormal_DNA_replication | 2.56856547 |
| 13 | MP0008877_abnormal_DNA_methylation | 2.40693060 |
| 14 | MP0003763_abnormal_thymus_physiology | 2.28574329 |
| 15 | MP0001790_abnormal_immune_system | 2.19909612 |
| 16 | MP0005387_immune_system_phenotype | 2.19909612 |
| 17 | MP0002452_abnormal_antigen_presenting | 2.14948667 |
| 18 | MP0003646_muscle_fatigue | 2.14891574 |
| 19 | MP0003303_peritoneal_inflammation | 2.12224491 |
| 20 | MP0000685_abnormal_immune_system | 2.09238259 |
| 21 | MP0003890_abnormal_embryonic-extraembry | 2.07020279 |
| 22 | MP0002723_abnormal_immune_serum | 2.06716564 |
| 23 | MP0003136_yellow_coat_color | 2.06394014 |
| 24 | MP0005075_abnormal_melanosome_morpholog | 2.01804709 |
| 25 | MP0009785_altered_susceptibility_to | 1.99305111 |
| 26 | MP0005174_abnormal_tail_pigmentation | 1.90108469 |
| 27 | MP0002420_abnormal_adaptive_immunity | 1.89632686 |
| 28 | MP0005000_abnormal_immune_tolerance | 1.87892437 |
| 29 | MP0001819_abnormal_immune_cell | 1.87707984 |
| 30 | MP0003300_gastrointestinal_ulcer | 1.85499035 |
| 31 | MP0002332_abnormal_exercise_endurance | 1.84247468 |
| 32 | MP0005671_abnormal_response_to | 1.81737869 |
| 33 | MP0003172_abnormal_lysosome_physiology | 1.81509943 |
| 34 | MP0000015_abnormal_ear_pigmentation | 1.72913260 |
| 35 | MP0005025_abnormal_response_to | 1.72106962 |
| 36 | MP0002419_abnormal_innate_immunity | 1.71298130 |
| 37 | MP0003656_abnormal_erythrocyte_physiolo | 1.70147002 |
| 38 | MP0002138_abnormal_hepatobiliary_system | 1.67632321 |
| 39 | MP0000716_abnormal_immune_system | 1.63606486 |
| 40 | MP0002398_abnormal_bone_marrow | 1.59258040 |
| 41 | MP0005451_abnormal_body_composition | 1.58617255 |
| 42 | MP0002166_altered_tumor_susceptibility | 1.50612014 |
| 43 | MP0000427_abnormal_hair_cycle | 1.50443574 |
| 44 | MP0002148_abnormal_hypersensitivity_rea | 1.44035401 |
| 45 | MP0000371_diluted_coat_color | 1.37145629 |
| 46 | MP0000689_abnormal_spleen_morphology | 1.35058957 |
| 47 | MP0003195_calcinosis | 1.33465454 |
| 48 | MP0004883_abnormal_blood_vessel | 1.31644433 |
| 49 | MP0002722_abnormal_immune_system | 1.31319997 |
| 50 | MP0003221_abnormal_cardiomyocyte_apopto | 1.29848786 |
| 51 | MP0003436_decreased_susceptibility_to | 1.28287967 |
| 52 | MP0002429_abnormal_blood_cell | 1.24752956 |
| 53 | MP0006082_CNS_inflammation | 1.22369638 |
| 54 | MP0001845_abnormal_inflammatory_respons | 1.20981633 |
| 55 | MP0000703_abnormal_thymus_morphology | 1.16897270 |
| 56 | MP0005310_abnormal_salivary_gland | 1.15564877 |
| 57 | MP0009764_decreased_sensitivity_to | 1.13663894 |
| 58 | MP0004808_abnormal_hematopoietic_stem | 1.09546326 |
| 59 | MP0000383_abnormal_hair_follicle | 1.05647766 |
| 60 | MP0002006_tumorigenesis | 1.05253089 |
| 61 | MP0002405_respiratory_system_inflammati | 1.04673368 |
| 62 | MP0001186_pigmentation_phenotype | 1.01036137 |
| 63 | MP0003183_abnormal_peptide_metabolism | 1.00000064 |
| 64 | MP0003121_genomic_imprinting | 0.99089957 |
| 65 | MP0002168_other_aberrant_phenotype | 0.98474667 |
| 66 | MP0005464_abnormal_platelet_physiology | 0.97428268 |
| 67 | MP0005164_abnormal_response_to | 0.94442356 |
| 68 | MP0004130_abnormal_muscle_cell | 0.94286663 |
| 69 | MP0003690_abnormal_glial_cell | 0.93150449 |
| 70 | MP0010155_abnormal_intestine_physiology | 0.92825550 |
| 71 | MP0003879_abnormal_hair_cell | 0.91717750 |
| 72 | MP0003866_abnormal_defecation | 0.91188992 |
| 73 | MP0002075_abnormal_coat/hair_pigmentati | 0.91034154 |
| 74 | MP0002095_abnormal_skin_pigmentation | 0.89502696 |
| 75 | MP0004484_altered_response_of | 0.89434768 |
| 76 | MP0006054_spinal_hemorrhage | 0.88034727 |
| 77 | MP0008469_abnormal_protein_level | 0.87738557 |
| 78 | MP0005266_abnormal_metabolism | 0.82427042 |
| 79 | MP0004272_abnormal_basement_membrane | 0.81055401 |
| 80 | MP0008961_abnormal_basal_metabolism | 0.79166680 |
| 81 | MP0005397_hematopoietic_system_phenotyp | 0.78947680 |
| 82 | MP0001545_abnormal_hematopoietic_system | 0.78947680 |
| 83 | MP0010678_abnormal_skin_adnexa | 0.78014480 |
| 84 | MP0009763_increased_sensitivity_to | 0.77914094 |
| 85 | MP0004947_skin_inflammation | 0.77338388 |
| 86 | MP0000858_altered_metastatic_potential | 0.74172816 |
| 87 | MP0005670_abnormal_white_adipose | 0.73659710 |
| 88 | MP0008874_decreased_physiological_sensi | 0.72014231 |
| 89 | MP0005376_homeostasis/metabolism_phenot | 0.70687707 |
| 90 | MP0002396_abnormal_hematopoietic_system | 0.69983941 |
| 91 | MP0001533_abnormal_skeleton_physiology | 0.65433838 |
| 92 | MP0003632_abnormal_nervous_system | 0.63172385 |
| 93 | MP0004147_increased_porphyrin_level | 0.61443574 |
| 94 | MP0002971_abnormal_brown_adipose | 0.59511338 |
| 95 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.58642492 |
| 96 | MP0005621_abnormal_cell_physiology | 0.56602291 |
| 97 | MP0009115_abnormal_fat_cell | 0.55932760 |
| 98 | MP0000604_amyloidosis | 0.55118903 |
| 99 | MP0000465_gastrointestinal_hemorrhage | 0.54265713 |
| 100 | MP0000249_abnormal_blood_vessel | 0.54016826 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Calf muscle hypertrophy (HP:0008981) | 6.08309173 |
| 2 | Type II lissencephaly (HP:0007260) | 5.52028212 |
| 3 | Muscle hypertrophy of the lower extremities (HP:0008968) | 5.33796338 |
| 4 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 5.33484982 |
| 5 | T lymphocytopenia (HP:0005403) | 5.00506936 |
| 6 | Recurrent bacterial skin infections (HP:0005406) | 4.95723286 |
| 7 | Abnormality of T cell number (HP:0011839) | 4.75029766 |
| 8 | Gastrointestinal stroma tumor (HP:0100723) | 4.71422187 |
| 9 | Optic neuritis (HP:0100653) | 4.46907005 |
| 10 | Retrobulbar optic neuritis (HP:0100654) | 4.46907005 |
| 11 | Amelogenesis imperfecta (HP:0000705) | 4.46736265 |
| 12 | Recurrent abscess formation (HP:0002722) | 4.25527509 |
| 13 | Vasculitis (HP:0002633) | 4.16978545 |
| 14 | Spontaneous hematomas (HP:0007420) | 4.10824832 |
| 15 | Orchitis (HP:0100796) | 4.01187079 |
| 16 | Retinal dysplasia (HP:0007973) | 3.78836593 |
| 17 | Myositis (HP:0100614) | 3.78001133 |
| 18 | Recurrent fungal infections (HP:0002841) | 3.55299149 |
| 19 | Eczematoid dermatitis (HP:0000976) | 3.54110660 |
| 20 | Acanthocytosis (HP:0001927) | 3.50292665 |
| 21 | Recurrent cutaneous fungal infections (HP:0011370) | 3.47376688 |
| 22 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.47376688 |
| 23 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.44195680 |
| 24 | Lymphopenia (HP:0001888) | 3.43631758 |
| 25 | Recurrent skin infections (HP:0001581) | 3.34642743 |
| 26 | Poikilocytosis (HP:0004447) | 3.26729712 |
| 27 | Gastrointestinal infarctions (HP:0005244) | 3.25944078 |
| 28 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.16040794 |
| 29 | Keratoconjunctivitis sicca (HP:0001097) | 3.07405597 |
| 30 | Colitis (HP:0002583) | 3.07391351 |
| 31 | Gingivitis (HP:0000230) | 3.05990582 |
| 32 | Conjunctival telangiectasia (HP:0000524) | 3.05055317 |
| 33 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 3.04560153 |
| 34 | Autoimmune hemolytic anemia (HP:0001890) | 2.93998660 |
| 35 | Abnormality of T cells (HP:0002843) | 2.91380474 |
| 36 | Hemoptysis (HP:0002105) | 2.85089636 |
| 37 | Recurrent viral infections (HP:0004429) | 2.82878911 |
| 38 | Keratoconjunctivitis (HP:0001096) | 2.81372011 |
| 39 | Gingival bleeding (HP:0000225) | 2.79243098 |
| 40 | Inflammation of the large intestine (HP:0002037) | 2.78687954 |
| 41 | Hematochezia (HP:0002573) | 2.77823539 |
| 42 | Arterial thrombosis (HP:0004420) | 2.76787564 |
| 43 | Postural instability (HP:0002172) | 2.73847507 |
| 44 | Stomach cancer (HP:0012126) | 2.68690191 |
| 45 | Gangrene (HP:0100758) | 2.65844859 |
| 46 | Peritonitis (HP:0002586) | 2.64366820 |
| 47 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.62944289 |
| 48 | Recurrent bronchitis (HP:0002837) | 2.60481735 |
| 49 | Abnormality of the fingertips (HP:0001211) | 2.57898141 |
| 50 | Meningitis (HP:0001287) | 2.54074296 |
| 51 | Mediastinal lymphadenopathy (HP:0100721) | 2.54059591 |
| 52 | Gastrointestinal inflammation (HP:0004386) | 2.50272013 |
| 53 | Emphysema (HP:0002097) | 2.48362943 |
| 54 | Leukocytosis (HP:0001974) | 2.48030042 |
| 55 | Encephalitis (HP:0002383) | 2.45464814 |
| 56 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.45349582 |
| 57 | Pulmonary embolism (HP:0002204) | 2.40438293 |
| 58 | Thyroiditis (HP:0100646) | 2.37393172 |
| 59 | Restrictive lung disease (HP:0002091) | 2.32852052 |
| 60 | Recurrent sinusitis (HP:0011108) | 2.30788546 |
| 61 | Parakeratosis (HP:0001036) | 2.28576724 |
| 62 | Genetic anticipation (HP:0003743) | 2.22485131 |
| 63 | Abnormality of macrophages (HP:0004311) | 2.22291066 |
| 64 | IgM deficiency (HP:0002850) | 2.22207255 |
| 65 | Acute hepatic failure (HP:0006554) | 2.22021841 |
| 66 | Keratitis (HP:0000491) | 2.20122074 |
| 67 | IgG deficiency (HP:0004315) | 2.18487220 |
| 68 | IgA deficiency (HP:0002720) | 2.18092434 |
| 69 | Focal motor seizures (HP:0011153) | 2.16978592 |
| 70 | Slow saccadic eye movements (HP:0000514) | 2.16388890 |
| 71 | Stomatitis (HP:0010280) | 2.15845289 |
| 72 | Visual hallucinations (HP:0002367) | 2.11500562 |
| 73 | Abnormality of eosinophils (HP:0001879) | 2.09195654 |
| 74 | Chest pain (HP:0100749) | 2.07678017 |
| 75 | Pulmonary infiltrates (HP:0002113) | 2.07223155 |
| 76 | Obstructive lung disease (HP:0006536) | 2.06779802 |
| 77 | Chronic obstructive pulmonary disease (HP:0006510) | 2.06779802 |
| 78 | Transposition of the great arteries (HP:0001669) | 2.06711443 |
| 79 | Abnormal connection of the cardiac segments (HP:0011545) | 2.06711443 |
| 80 | Abnormal ventriculo-arterial connection (HP:0011563) | 2.06711443 |
| 81 | Abnormality of the calf musculature (HP:0001430) | 2.04577634 |
| 82 | Poikiloderma (HP:0001029) | 2.02148203 |
| 83 | Periodontitis (HP:0000704) | 2.01857712 |
| 84 | Leukopenia (HP:0001882) | 1.99997965 |
| 85 | Muscular dystrophy (HP:0003560) | 1.99892047 |
| 86 | Esophageal varix (HP:0002040) | 1.98251535 |
| 87 | Eosinophilia (HP:0001880) | 1.98097974 |
| 88 | Epistaxis (HP:0000421) | 1.96608805 |
| 89 | Anorexia (HP:0002039) | 1.94654980 |
| 90 | Abnormality of DNA repair (HP:0003254) | 1.94631395 |
| 91 | Viral hepatitis (HP:0006562) | 1.94227633 |
| 92 | Lymphoma (HP:0002665) | 1.92431084 |
| 93 | Sepsis (HP:0100806) | 1.91762421 |
| 94 | Autoimmune thrombocytopenia (HP:0001973) | 1.87707969 |
| 95 | Abnormality of T cell physiology (HP:0011840) | 1.86278528 |
| 96 | Portal hypertension (HP:0001409) | 1.85979494 |
| 97 | Porencephaly (HP:0002132) | 1.85953847 |
| 98 | Subacute progressive viral hepatitis (HP:0006572) | 1.82124800 |
| 99 | Entropion (HP:0000621) | 1.80608335 |
| 100 | Ectropion (HP:0000656) | 1.80483457 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK19 | 5.53851590 |
| 2 | LATS1 | 5.04253484 |
| 3 | STK38L | 3.17331335 |
| 4 | FRK | 2.98510379 |
| 5 | RIPK4 | 2.96682181 |
| 6 | IRAK4 | 2.32038150 |
| 7 | LATS2 | 2.21257357 |
| 8 | BLK | 2.19530532 |
| 9 | IKBKE | 2.15441886 |
| 10 | TEC | 2.05513093 |
| 11 | NLK | 2.02803978 |
| 12 | GRK6 | 2.01358093 |
| 13 | TXK | 2.01028086 |
| 14 | ACVR1B | 2.00300245 |
| 15 | JAK3 | 1.86351537 |
| 16 | MAP4K1 | 1.79693973 |
| 17 | FGR | 1.75903478 |
| 18 | MAP3K2 | 1.73335620 |
| 19 | TAOK3 | 1.71155218 |
| 20 | BTK | 1.70171449 |
| 21 | SYK | 1.69584911 |
| 22 | PIK3CG | 1.68605539 |
| 23 | CSK | 1.62069986 |
| 24 | STK38 | 1.61306260 |
| 25 | MAP3K13 | 1.58545819 |
| 26 | ITK | 1.52953622 |
| 27 | BMPR2 | 1.51512910 |
| 28 | TYK2 | 1.48351133 |
| 29 | JAK1 | 1.47661719 |
| 30 | PTK2B | 1.44542069 |
| 31 | GRK5 | 1.41118379 |
| 32 | MELK | 1.36902545 |
| 33 | FES | 1.24382765 |
| 34 | FGFR3 | 1.13429536 |
| 35 | MATK | 1.12551493 |
| 36 | MARK2 | 1.10209517 |
| 37 | KSR2 | 1.09195549 |
| 38 | STK3 | 1.07373908 |
| 39 | MAP3K14 | 1.05677893 |
| 40 | PIM1 | 0.99725354 |
| 41 | PLK2 | 0.98885076 |
| 42 | LYN | 0.94720857 |
| 43 | GRK7 | 0.90372535 |
| 44 | IRAK1 | 0.86148253 |
| 45 | WNK1 | 0.84664044 |
| 46 | PDPK1 | 0.80748745 |
| 47 | HCK | 0.79622253 |
| 48 | MAP3K10 | 0.79084045 |
| 49 | JAK2 | 0.78646471 |
| 50 | ERBB2 | 0.78168426 |
| 51 | IKBKB | 0.76544434 |
| 52 | SGK2 | 0.74179130 |
| 53 | STK4 | 0.73342798 |
| 54 | MAP2K3 | 0.72429190 |
| 55 | FGFR4 | 0.71976863 |
| 56 | MARK3 | 0.71486359 |
| 57 | BMPR1B | 0.69339697 |
| 58 | PRKAA2 | 0.66130282 |
| 59 | MAP3K1 | 0.65804249 |
| 60 | TGFBR2 | 0.64638965 |
| 61 | KIT | 0.63829755 |
| 62 | CHUK | 0.63705791 |
| 63 | IRAK2 | 0.63351258 |
| 64 | LCK | 0.63341154 |
| 65 | MOS | 0.62265643 |
| 66 | MAP2K2 | 0.61852668 |
| 67 | KSR1 | 0.61838038 |
| 68 | MAP2K6 | 0.61251511 |
| 69 | LRRK2 | 0.60930466 |
| 70 | CDK12 | 0.59997219 |
| 71 | MAPK11 | 0.59670950 |
| 72 | DYRK1A | 0.59463604 |
| 73 | ADRBK2 | 0.59369799 |
| 74 | ADRBK1 | 0.58844181 |
| 75 | PDK1 | 0.58418266 |
| 76 | ZAP70 | 0.57394676 |
| 77 | TRPM7 | 0.55536032 |
| 78 | MAP3K7 | 0.54820186 |
| 79 | MAP3K6 | 0.54263597 |
| 80 | RPS6KB1 | 0.52533890 |
| 81 | TBK1 | 0.49253062 |
| 82 | CDC42BPA | 0.49151227 |
| 83 | STK11 | 0.48636508 |
| 84 | EIF2AK2 | 0.48540386 |
| 85 | NEK9 | 0.46254371 |
| 86 | CSF1R | 0.46174688 |
| 87 | SIK3 | 0.41412949 |
| 88 | PRKD1 | 0.39101115 |
| 89 | STK10 | 0.39051334 |
| 90 | EGFR | 0.36334688 |
| 91 | MAPK7 | 0.35798713 |
| 92 | SGK1 | 0.35233605 |
| 93 | RAF1 | 0.34457104 |
| 94 | SGK3 | 0.34177850 |
| 95 | PRKCZ | 0.33245762 |
| 96 | DAPK2 | 0.31335609 |
| 97 | DYRK3 | 0.31151528 |
| 98 | ABL1 | 0.29697912 |
| 99 | SGK223 | 0.29273917 |
| 100 | SGK494 | 0.29273917 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.77314757 |
| 2 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.30362205 |
| 3 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.27951138 |
| 4 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.21532131 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.20859337 |
| 6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.18499649 |
| 7 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.16317678 |
| 8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.07448364 |
| 9 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.99908814 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.98818811 |
| 11 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.98540270 |
| 12 | Allograft rejection_Homo sapiens_hsa05330 | 1.97705894 |
| 13 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.93045219 |
| 14 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.92363070 |
| 15 | Tuberculosis_Homo sapiens_hsa05152 | 1.89322833 |
| 16 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.78693303 |
| 17 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.74881738 |
| 18 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.74692435 |
| 19 | Asthma_Homo sapiens_hsa05310 | 1.74108382 |
| 20 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.68589256 |
| 21 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.67762859 |
| 22 | Measles_Homo sapiens_hsa05162 | 1.64171362 |
| 23 | Influenza A_Homo sapiens_hsa05164 | 1.61580979 |
| 24 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.58617494 |
| 25 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.43781406 |
| 26 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.42450338 |
| 27 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.41329511 |
| 28 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.39395444 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.34904961 |
| 30 | Legionellosis_Homo sapiens_hsa05134 | 1.32914524 |
| 31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.31962371 |
| 32 | Viral myocarditis_Homo sapiens_hsa05416 | 1.29804998 |
| 33 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.26850668 |
| 34 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.24490351 |
| 35 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.19717976 |
| 36 | Hepatitis B_Homo sapiens_hsa05161 | 1.17242010 |
| 37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.12860034 |
| 38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.10816166 |
| 39 | Malaria_Homo sapiens_hsa05144 | 1.10466366 |
| 40 | Phototransduction_Homo sapiens_hsa04744 | 1.10454024 |
| 41 | Hepatitis C_Homo sapiens_hsa05160 | 1.08999070 |
| 42 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.04889164 |
| 43 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.03620477 |
| 44 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.03434971 |
| 45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.01506598 |
| 46 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.99998549 |
| 47 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.98888041 |
| 48 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.93267287 |
| 49 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.91165108 |
| 50 | Platelet activation_Homo sapiens_hsa04611 | 0.90599953 |
| 51 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.88541201 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.85766879 |
| 53 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.81637008 |
| 54 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.79729828 |
| 55 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.79530927 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.78624170 |
| 57 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.77542226 |
| 58 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.72998000 |
| 59 | Pertussis_Homo sapiens_hsa05133 | 0.71496552 |
| 60 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.70238924 |
| 61 | Apoptosis_Homo sapiens_hsa04210 | 0.69978294 |
| 62 | Phagosome_Homo sapiens_hsa04145 | 0.69385384 |
| 63 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.69184240 |
| 64 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.65950343 |
| 65 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64026948 |
| 66 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.63621742 |
| 67 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.62715860 |
| 68 | Endometrial cancer_Homo sapiens_hsa05213 | 0.61581501 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.60631779 |
| 70 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.59133257 |
| 71 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.58200336 |
| 72 | ABC transporters_Homo sapiens_hsa02010 | 0.56806907 |
| 73 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.55972846 |
| 74 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.55715790 |
| 75 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.55402870 |
| 76 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55172154 |
| 77 | HTLV-I infection_Homo sapiens_hsa05166 | 0.55113044 |
| 78 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.54410806 |
| 79 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.53328600 |
| 80 | Lysine degradation_Homo sapiens_hsa00310 | 0.52659711 |
| 81 | Glioma_Homo sapiens_hsa05214 | 0.51306728 |
| 82 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.46911087 |
| 83 | Morphine addiction_Homo sapiens_hsa05032 | 0.46668655 |
| 84 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.45889477 |
| 85 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.45590791 |
| 86 | Nicotine addiction_Homo sapiens_hsa05033 | 0.44217354 |
| 87 | Long-term potentiation_Homo sapiens_hsa04720 | 0.44047785 |
| 88 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.43543392 |
| 89 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.41330649 |
| 90 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.39462983 |
| 91 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.39438486 |
| 92 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.38668006 |
| 93 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.38057155 |
| 94 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.37561857 |
| 95 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.35513345 |
| 96 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.35140019 |
| 97 | Colorectal cancer_Homo sapiens_hsa05210 | 0.34971367 |
| 98 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.34773102 |
| 99 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.33896979 |
| 100 | Thyroid cancer_Homo sapiens_hsa05216 | 0.33237528 |

