ZDHHC7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation by symbiont of host defense response (GO:0052509)4.10772669
2modulation by symbiont of host defense response (GO:0052031)4.10772669
3modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.10772669
4modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.10772669
5positive regulation by organism of defense response of other organism involved in symbiotic interact4.10772669
6modulation by symbiont of host immune response (GO:0052553)4.10772669
7NADH metabolic process (GO:0006734)4.07354946
8folic acid metabolic process (GO:0046655)3.95499595
9pentose-phosphate shunt (GO:0006098)3.93069907
10negative regulation of erythrocyte differentiation (GO:0045647)3.92731918
11vitamin transmembrane transport (GO:0035461)3.89063411
12response to peptidoglycan (GO:0032494)3.87324634
13antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.77532103
14antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.77532103
15pinocytosis (GO:0006907)3.69073305
16negative regulation of cell killing (GO:0031342)3.54407466
17negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.54407466
18response to laminar fluid shear stress (GO:0034616)3.42930762
19CDP-diacylglycerol metabolic process (GO:0046341)3.42577041
20detection of other organism (GO:0098543)3.42525895
21NADPH regeneration (GO:0006740)3.40305704
22purine nucleobase biosynthetic process (GO:0009113)3.35475753
23positive regulation of Cdc42 GTPase activity (GO:0043089)3.34153881
24neutrophil activation involved in immune response (GO:0002283)3.32361392
25regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.31741780
26hypotonic response (GO:0006971)3.29352136
27macrophage activation involved in immune response (GO:0002281)3.22909249
28folic acid transport (GO:0015884)3.21915151
29regulation of leukocyte degranulation (GO:0043300)3.21812818
30positive regulation of triglyceride biosynthetic process (GO:0010867)3.19882782
31antigen processing and presentation of endogenous antigen (GO:0019883)3.19113771
32regulation of spindle organization (GO:0090224)3.17741718
33stress fiber assembly (GO:0043149)3.17575260
34detection of bacterium (GO:0016045)3.14812968
35detection of molecule of bacterial origin (GO:0032490)3.14393435
36glucose catabolic process (GO:0006007)3.11214486
37barbed-end actin filament capping (GO:0051016)3.10806434
38Arp2/3 complex-mediated actin nucleation (GO:0034314)3.08305351
39modified amino acid transport (GO:0072337)3.07673165
40regulation of gamma-delta T cell differentiation (GO:0045586)3.07199265
41histone-serine phosphorylation (GO:0035404)3.06566057
42low-density lipoprotein particle clearance (GO:0034383)3.03856977
43regulation of cholesterol storage (GO:0010885)3.02914182
44negative regulation of cell size (GO:0045792)3.01381253
45regulation of mast cell degranulation (GO:0043304)3.00506896
46detection of external biotic stimulus (GO:0098581)3.00419626
47skin morphogenesis (GO:0043589)3.00385831
48antigen processing and presentation via MHC class Ib (GO:0002475)3.00302137
49response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.95751946
50response to host (GO:0075136)2.95751946
51response to host defenses (GO:0052200)2.95751946
52embryonic process involved in female pregnancy (GO:0060136)2.95012715
53regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.93855631
54positive regulation of triglyceride metabolic process (GO:0090208)2.93694968
55cellular extravasation (GO:0045123)2.93564143
56positive regulation of gamma-delta T cell activation (GO:0046645)2.93066763
57regulation of myeloid leukocyte mediated immunity (GO:0002886)2.92488174
58regulation of response to interferon-gamma (GO:0060330)2.90843796
59regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.90565157
60positive regulation of receptor recycling (GO:0001921)2.88430302
61response to muramyl dipeptide (GO:0032495)2.86304000
62regulation of cholesterol homeostasis (GO:2000188)2.85825027
63focal adhesion assembly (GO:0048041)2.84647692
64cell-substrate adherens junction assembly (GO:0007045)2.84647692
65nucleobase biosynthetic process (GO:0046112)2.84517934
66maternal placenta development (GO:0001893)2.83391723
67purine nucleotide salvage (GO:0032261)2.83240093
68negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.81665138
69negative regulation of innate immune response (GO:0045824)2.81376750
702-oxoglutarate metabolic process (GO:0006103)2.81177123
71regulation of type I interferon-mediated signaling pathway (GO:0060338)2.80446833
72cell-substrate junction assembly (GO:0007044)2.79829713
73regulation of gamma-delta T cell activation (GO:0046643)2.76100175
74epithelial cell differentiation involved in prostate gland development (GO:0060742)2.75452920
75regulation of extracellular matrix disassembly (GO:0010715)2.74919247
76regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.74546137
77positive regulation of leukocyte degranulation (GO:0043302)2.74400539
78CDP-diacylglycerol biosynthetic process (GO:0016024)2.74029603
79positive regulation of extracellular matrix organization (GO:1903055)2.72847686
80positive thymic T cell selection (GO:0045059)2.72015633
81regulation of interferon-beta biosynthetic process (GO:0045357)2.71421788
82basement membrane organization (GO:0071711)2.71006770
83regulation of fatty acid beta-oxidation (GO:0031998)2.70780292
84glycine metabolic process (GO:0006544)2.70217833
85adherens junction assembly (GO:0034333)2.69898000
86UDP-N-acetylglucosamine metabolic process (GO:0006047)2.67296924
87detection of biotic stimulus (GO:0009595)2.66296948
88positive regulation of lamellipodium assembly (GO:0010592)2.65966379
89response to host immune response (GO:0052572)2.65574074
90response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.65574074
91morphogenesis of an endothelium (GO:0003159)2.64316004
92endothelial tube morphogenesis (GO:0061154)2.64316004
93positive regulation of membrane protein ectodomain proteolysis (GO:0051044)2.63984327
94regulation of T-helper 2 cell differentiation (GO:0045628)2.63560220
95regulation of mast cell activation involved in immune response (GO:0033006)2.63147606
96regulation of translational termination (GO:0006449)2.62940198
97cellular response to arsenic-containing substance (GO:0071243)2.62067407
98ribosome assembly (GO:0042255)2.61647923
99protein localization to endosome (GO:0036010)2.60756994
100cellular response to thyroid hormone stimulus (GO:0097067)2.59225613
101positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.58412434
102lipopolysaccharide-mediated signaling pathway (GO:0031663)2.56193087
103pantothenate metabolic process (GO:0015939)2.54947369
104positive regulation of cellular amide metabolic process (GO:0034250)2.54852371
105regulation of regulated secretory pathway (GO:1903305)2.53423215
106mannose metabolic process (GO:0006013)2.52609955
107regulation of macrophage cytokine production (GO:0010935)2.52339490
108biotin metabolic process (GO:0006768)2.52079356
109serine family amino acid catabolic process (GO:0009071)2.50907553
110positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.49800043
111regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.49393155
112lysine catabolic process (GO:0006554)2.49168654
113lysine metabolic process (GO:0006553)2.49168654
114cortical actin cytoskeleton organization (GO:0030866)2.48601856
115antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.48440092
116nucleoside salvage (GO:0043174)2.48086813
117mitotic G1 DNA damage checkpoint (GO:0031571)2.47133482
118nucleotide salvage (GO:0043173)2.45833315
119negative regulation of protein localization to plasma membrane (GO:1903077)2.43928846
120positive regulation of lipid storage (GO:0010884)2.42401105
121negative regulation of interleukin-12 production (GO:0032695)2.42315544
122regulation of mitotic spindle organization (GO:0060236)2.41690338
123positive regulation of blood vessel endothelial cell migration (GO:0043536)2.40808936
124epithelial cell-cell adhesion (GO:0090136)2.39649279
125negative regulation of lipid transport (GO:0032369)2.39127123
126protein localization to kinetochore (GO:0034501)2.37376777
127glycosphingolipid catabolic process (GO:0046479)2.37107629
128regulation of early endosome to late endosome transport (GO:2000641)2.36445948
129regulation of fatty acid oxidation (GO:0046320)2.36246962
130regulation of necroptotic process (GO:0060544)2.36074329
131cellular response to zinc ion (GO:0071294)2.35595949
132modulation by symbiont of host cellular process (GO:0044068)2.34873444
133positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.33698116
134skeletal muscle tissue regeneration (GO:0043403)2.33437063
135galactose catabolic process (GO:0019388)2.33304259
136T cell apoptotic process (GO:0070231)2.32211785
137leukocyte aggregation (GO:0070486)2.32116396
138positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.31488582
139negative regulation of toll-like receptor signaling pathway (GO:0034122)2.31270613
140membrane raft organization (GO:0031579)2.30995332
141tricarboxylic acid cycle (GO:0006099)2.30834955
142apoptotic cell clearance (GO:0043277)2.30712846
143tricarboxylic acid metabolic process (GO:0072350)2.30691790
144vitamin transport (GO:0051180)2.30227584
145mitotic metaphase plate congression (GO:0007080)2.30158180
146positive regulation of mast cell activation (GO:0033005)2.29875582
147negative regulation of fatty acid transport (GO:2000192)2.28232816
1483-UTR-mediated mRNA stabilization (GO:0070935)2.26434427
149regulation of superoxide anion generation (GO:0032928)2.26251311
150positive regulation of regulated secretory pathway (GO:1903307)2.26177727
151cysteine metabolic process (GO:0006534)2.26133805
152mitotic nuclear envelope disassembly (GO:0007077)2.25731470
153positive regulation of lamellipodium organization (GO:1902745)2.25632541
154hyaluronan catabolic process (GO:0030214)2.25541296
155monoubiquitinated protein deubiquitination (GO:0035520)2.25353695
156sarcomere organization (GO:0045214)2.25324313
157Golgi transport vesicle coating (GO:0048200)2.25021844
158COPI coating of Golgi vesicle (GO:0048205)2.25021844
159cytokinetic process (GO:0032506)2.24909111
160regulation of histone phosphorylation (GO:0033127)2.23768501
161positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.23464675
162peptide catabolic process (GO:0043171)2.23014987
163formation of translation preinitiation complex (GO:0001731)2.22923748
164protein localization to chromosome, centromeric region (GO:0071459)2.22866556
165protein retention in ER lumen (GO:0006621)2.22806527
166macrophage activation (GO:0042116)2.21008154
167NIK/NF-kappaB signaling (GO:0038061)2.20650927
168regulation of interleukin-12 biosynthetic process (GO:0045075)2.20472949
169response to thyroid hormone (GO:0097066)2.20093865
170purine nucleobase metabolic process (GO:0006144)2.19953021
171regulation of tight junction assembly (GO:2000810)2.19711666
172respiratory burst (GO:0045730)2.18845838
173regulation of triglyceride catabolic process (GO:0010896)2.18522801
174membrane protein ectodomain proteolysis (GO:0006509)2.18374622
175regulation of lipid kinase activity (GO:0043550)2.18340928
176immunoglobulin mediated immune response (GO:0016064)2.17379009
177negative regulation of necroptotic process (GO:0060546)2.16834506
178cortical cytoskeleton organization (GO:0030865)2.16132905
179JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.16022407
180regulation of extracellular matrix organization (GO:1903053)2.15865370
181pyrimidine nucleoside salvage (GO:0043097)2.15560419
182regulation of defense response to virus by virus (GO:0050690)2.15129523
183positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.13307532

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.19903615
2FOXM1_23109430_ChIP-Seq_U2OS_Human2.86642885
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.78954672
4E2F7_22180533_ChIP-Seq_HELA_Human2.78657019
5MYC_22102868_ChIP-Seq_BL_Human2.74402843
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.54075992
7ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.41135862
8ZNF263_19887448_ChIP-Seq_K562_Human2.21322794
9VDR_21846776_ChIP-Seq_THP-1_Human2.18965072
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.13628365
11STAT6_21828071_ChIP-Seq_BEAS2B_Human2.06940922
12ELK3_25401928_ChIP-Seq_HUVEC_Human2.02697409
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.95161186
14BP1_19119308_ChIP-ChIP_Hs578T_Human1.93317931
15ESR2_21235772_ChIP-Seq_MCF-7_Human1.92472296
16PPARA_22158963_ChIP-Seq_LIVER_Mouse1.91920978
17NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.82320353
18RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.76357386
19MYB_21317192_ChIP-Seq_ERMYB_Mouse1.75165449
20CLOCK_20551151_ChIP-Seq_293T_Human1.73349703
21RXR_22158963_ChIP-Seq_LIVER_Mouse1.70454825
22KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.66484288
23MAF_26560356_Chip-Seq_TH1_Human1.62506675
24KDM2B_26808549_Chip-Seq_DND41_Human1.62453991
25RARG_19884340_ChIP-ChIP_MEFs_Mouse1.60765795
26MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.60649332
27TCF7_22412390_ChIP-Seq_EML_Mouse1.58888308
28BRD4_27068464_Chip-Seq_AML-cells_Mouse1.55642446
29RACK7_27058665_Chip-Seq_MCF-7_Human1.55075396
30E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.53465397
31TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.52980263
32KDM2B_26808549_Chip-Seq_K562_Human1.52335904
33TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.52181879
34LXR_22292898_ChIP-Seq_THP-1_Human1.51791120
35AR_21909140_ChIP-Seq_LNCAP_Human1.50255114
36KDM2B_26808549_Chip-Seq_SUP-B15_Human1.49414790
37CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.49122096
38ATF3_27146783_Chip-Seq_COLON_Human1.49028256
39* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.48268211
40THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.47426088
41* UTX_26944678_Chip-Seq_JUKART_Human1.44979987
42KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.41953660
43KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.40366588
44STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.39982882
45ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.39840709
46* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.39350363
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.38261015
48STAT3_1855785_ChIP-Seq_MESCs_Mouse1.37898878
49VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.35550747
50VDR_24763502_ChIP-Seq_THP-1_Human1.33651672
51IRF8_21731497_ChIP-ChIP_J774_Mouse1.33584223
52KDM2B_26808549_Chip-Seq_JURKAT_Human1.32988559
53KLF4_18555785_ChIP-Seq_MESCs_Mouse1.31103999
54IRF8_22096565_ChIP-ChIP_GC-B_Human1.30273728
55RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.29349605
56ESR1_21235772_ChIP-Seq_MCF-7_Human1.26993518
57BCOR_27268052_Chip-Seq_Bcells_Human1.26651136
58MAF_26560356_Chip-Seq_TH2_Human1.25344055
59CREB1_15753290_ChIP-ChIP_HEK293T_Human1.25141808
60P68_20966046_ChIP-Seq_HELA_Human1.24803116
61WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.24746061
62RUNX1_22412390_ChIP-Seq_EML_Mouse1.23648058
63GATA1_22383799_ChIP-Seq_G1ME_Mouse1.23166251
64STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.22780364
65MYC_18555785_ChIP-Seq_MESCs_Mouse1.22657725
66PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.20631310
67FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.19976800
68KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.19560059
69CTCF_27219007_Chip-Seq_ERYTHROID_Human1.19420369
70ZFP281_18757296_ChIP-ChIP_E14_Mouse1.18655076
71DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17185501
72TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16503138
73SPI1_23127762_ChIP-Seq_K562_Human1.16269956
74P300_27058665_Chip-Seq_ZR-75-30cells_Human1.16261298
75STAT4_19710469_ChIP-ChIP_TH1__Mouse1.16258577
76SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.15713734
77CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15630332
78TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.15531012
79LXR_22158963_ChIP-Seq_LIVER_Mouse1.15330478
80* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.15247501
81NCOR1_26117541_ChIP-Seq_K562_Human1.14671079
82STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.14273619
83SPI1_23547873_ChIP-Seq_NB4_Human1.13493841
84TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.13183221
85BCL6_27268052_Chip-Seq_Bcells_Human1.12880117
86SCL_19346495_ChIP-Seq_HPC-7_Human1.12787957
87RUNX1_27514584_Chip-Seq_MCF-7_Human1.12432106
88MYC_18358816_ChIP-ChIP_MESCs_Mouse1.12127553
89ESR1_20079471_ChIP-ChIP_T-47D_Human1.11981451
90ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.11769674
91MYB_26560356_Chip-Seq_TH2_Human1.11664212
92MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.10907066
93CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10745878
94SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10504459
95SOX2_27498859_Chip-Seq_STOMACH_Mouse1.10199799
96TBX20_22080862_ChIP-Seq_HEART_Mouse1.10031919
97TBX20_22328084_ChIP-Seq_HEART_Mouse1.10031919
98EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.09732263
99MYC_19079543_ChIP-ChIP_MESCs_Mouse1.09141841
100FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.08490442
101SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.08340114
102SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.08340114
103NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.08077084
104UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.07754778
105IRF8_27001747_Chip-Seq_BMDM_Mouse1.07689678
106GATA2_21666600_ChIP-Seq_HMVEC_Human1.07367275
107FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.07262170
108ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.06949886
109* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.06910165
110XRN2_22483619_ChIP-Seq_HELA_Human1.06842681
111* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.06347087
112MYB_26560356_Chip-Seq_TH1_Human1.06023481
113TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.05865007
114* GATA1_19941826_ChIP-Seq_K562_Human1.04169873
115SA1_27219007_Chip-Seq_ERYTHROID_Human1.04093882
116PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.03953150
117GATA1_19941827_ChIP-Seq_MEL_Mouse1.03619738
118ETS1_20019798_ChIP-Seq_JURKAT_Human1.03605376
119FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.03173346
120UBF1/2_26484160_Chip-Seq_HMECs_Human1.02596815
121SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.02552791
122FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.01937604
123KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01661693
124P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01554877
125GATA2_22383799_ChIP-Seq_G1ME_Mouse1.01547759
126CIITA_25753668_ChIP-Seq_RAJI_Human1.01430571
127SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.00970591
128SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.00368186
129CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00141184
130RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.99652148
131* GABP_19822575_ChIP-Seq_HepG2_Human0.99466645
132SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.99334427
133CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.99131470
134ELF1_20517297_ChIP-Seq_JURKAT_Human0.98392373
135PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97645499
136TP63_17297297_ChIP-ChIP_HaCaT_Human0.97345452
137GATA6_25053715_ChIP-Seq_YYC3_Human0.96818965
138PHF8_20622854_ChIP-Seq_HELA_Human0.95880284
139KDM5A_27292631_Chip-Seq_BREAST_Human0.95446391
140CTCF_21964334_Chip-Seq_Bcells_Human0.95395480

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009840_abnormal_foam_cell3.73129980
2MP0003705_abnormal_hypodermis_morpholog2.99646829
3MP0003303_peritoneal_inflammation2.26893518
4MP0005360_urolithiasis2.21869290
5MP0003693_abnormal_embryo_hatching2.17459134
6MP0003172_abnormal_lysosome_physiology2.09697598
7MP0003191_abnormal_cellular_cholesterol2.07639602
8MP0003724_increased_susceptibility_to1.99116950
9MP0001958_emphysema1.94385778
10MP0002877_abnormal_melanocyte_morpholog1.92081377
11MP0003656_abnormal_erythrocyte_physiolo1.90651472
12MP0006082_CNS_inflammation1.87955868
13MP0003091_abnormal_cell_migration1.81761304
14MP0009333_abnormal_splenocyte_physiolog1.80748308
15MP0003436_decreased_susceptibility_to1.73387482
16MP0003300_gastrointestinal_ulcer1.72929476
17MP0005409_darkened_coat_color1.70610158
18MP0004084_abnormal_cardiac_muscle1.69017937
19MP0005451_abnormal_body_composition1.63131989
20MP0003646_muscle_fatigue1.60978509
21MP0004858_abnormal_nervous_system1.58971454
22MP0003279_aneurysm1.58463408
23MP0002396_abnormal_hematopoietic_system1.57396756
24MP0005058_abnormal_lysosome_morphology1.55763470
25MP0009278_abnormal_bone_marrow1.54855340
26MP0004185_abnormal_adipocyte_glucose1.54847880
27MP0010307_abnormal_tumor_latency1.54068925
28MP0002998_abnormal_bone_remodeling1.53900560
29MP0001545_abnormal_hematopoietic_system1.51727205
30MP0005397_hematopoietic_system_phenotyp1.51727205
31MP0008260_abnormal_autophagy1.51598537
32MP0004130_abnormal_muscle_cell1.49454513
33MP0005257_abnormal_intraocular_pressure1.49355732
34MP0010352_gastrointestinal_tract_polyps1.48252687
35MP0000685_abnormal_immune_system1.47057113
36MP0010234_abnormal_vibrissa_follicle1.45492897
37MP0003566_abnormal_cell_adhesion1.44672665
38MP0003221_abnormal_cardiomyocyte_apopto1.41190625
39MP0003453_abnormal_keratinocyte_physiol1.39448257
40MP0004947_skin_inflammation1.37982841
41MP0003111_abnormal_nucleus_morphology1.37375789
42MP0010329_abnormal_lipoprotein_level1.37176819
43MP0004510_myositis1.36147696
44MP0002166_altered_tumor_susceptibility1.31871517
45MP0004233_abnormal_muscle_weight1.31795961
46MP0000609_abnormal_liver_physiology1.31727116
47MP0000750_abnormal_muscle_regeneration1.31621192
48MP0001835_abnormal_antigen_presentation1.30852590
49MP0005377_hearing/vestibular/ear_phenot1.29972444
50MP0003878_abnormal_ear_physiology1.29972444
51MP0001730_embryonic_growth_arrest1.26023656
52MP0005666_abnormal_adipose_tissue1.25876041
53MP0004272_abnormal_basement_membrane1.23146268
54MP0005167_abnormal_blood-brain_barrier1.22253032
55MP0005365_abnormal_bile_salt1.20057242
56MP0005464_abnormal_platelet_physiology1.19814196
57MP0000767_abnormal_smooth_muscle1.19569460
58MP0003183_abnormal_peptide_metabolism1.18487259
59MP0004808_abnormal_hematopoietic_stem1.17996510
60MP0005330_cardiomyopathy1.17487296
61MP0005076_abnormal_cell_differentiation1.17242449
62MP0004883_abnormal_blood_vessel1.17089518
63MP0010155_abnormal_intestine_physiology1.16999506
64MP0000747_muscle_weakness1.14706728
65MP0001666_abnormal_nutrient_absorption1.14398105
66MP0005164_abnormal_response_to1.14277623
67MP0004264_abnormal_extraembryonic_tissu1.14197771
68MP0001800_abnormal_humoral_immune1.13507623
69MP0005275_abnormal_skin_tensile1.13259183
70MP0002452_abnormal_antigen_presenting1.11538967
71MP0005319_abnormal_enzyme/_coenzyme1.11274573
72MP0006054_spinal_hemorrhage1.09239285
73MP0004957_abnormal_blastocyst_morpholog1.09222298
74MP0002398_abnormal_bone_marrow1.09090059
75MP0002419_abnormal_innate_immunity1.09040945
76MP0002060_abnormal_skin_morphology1.08389484
77MP0002796_impaired_skin_barrier1.07794112
78MP0000490_abnormal_crypts_of1.07172866
79MP0001915_intracranial_hemorrhage1.06644756
80MP0000604_amyloidosis1.06133288
81MP0002722_abnormal_immune_system1.05282115
82MP0001819_abnormal_immune_cell1.05027968
83MP0003448_altered_tumor_morphology1.04887848
84MP0000465_gastrointestinal_hemorrhage1.04699827
85MP0001851_eye_inflammation1.04248155
86MP0002420_abnormal_adaptive_immunity1.03700453
87MP0005000_abnormal_immune_tolerance1.03550840
88MP0003329_amyloid_beta_deposits1.03070573
89MP0005025_abnormal_response_to1.02745306
90MP0009643_abnormal_urine_homeostasis1.02256834
91MP0010630_abnormal_cardiac_muscle1.01616896
92MP0003075_altered_response_to1.01363478
93MP0002723_abnormal_immune_serum1.00917829
94MP0001533_abnormal_skeleton_physiology1.00522060
95MP0003866_abnormal_defecation1.00238195
96MP0000689_abnormal_spleen_morphology0.99963576
97MP0009384_cardiac_valve_regurgitation0.99625229
98MP0001845_abnormal_inflammatory_respons0.99420472
99MP0002896_abnormal_bone_mineralization0.99117362
100MP0000858_altered_metastatic_potential0.98424809
101MP0004087_abnormal_muscle_fiber0.98347800
102MP0005390_skeleton_phenotype0.97947622
103MP0002139_abnormal_hepatobiliary_system0.97086824
104MP0008438_abnormal_cutaneous_collagen0.96041980
105MP0003077_abnormal_cell_cycle0.95207891
106MP0003828_pulmonary_edema0.94981159
107MP0009785_altered_susceptibility_to0.94067715
108MP0000716_abnormal_immune_system0.93871348
109MP0001790_abnormal_immune_system0.93428673
110MP0005387_immune_system_phenotype0.93428673
111MP0000733_abnormal_muscle_development0.92862603
112MP0008004_abnormal_stomach_pH0.92603668
113MP0002429_abnormal_blood_cell0.92570468
114MP0002269_muscular_atrophy0.92022289
115MP0002405_respiratory_system_inflammati0.91319467
116MP0002132_abnormal_respiratory_system0.91317268
117MP0005375_adipose_tissue_phenotype0.90433842
118MP0005670_abnormal_white_adipose0.90297437
119MP0008469_abnormal_protein_level0.90012947
120MP0002837_dystrophic_cardiac_calcinosis0.89934040
121MP0005310_abnormal_salivary_gland0.89932001
122MP0004036_abnormal_muscle_relaxation0.89539804
123MP0000751_myopathy0.89445250
124MP0003252_abnormal_bile_duct0.87856898
125MP0001873_stomach_inflammation0.87553193
126MP0001849_ear_inflammation0.87151604
127MP0002148_abnormal_hypersensitivity_rea0.87134578
128MP0003795_abnormal_bone_structure0.86239085
129MP0001542_abnormal_bone_strength0.85646967
130MP0003763_abnormal_thymus_physiology0.85260116
131MP0005332_abnormal_amino_acid0.85094023
132MP0008961_abnormal_basal_metabolism0.85017981
133MP0000343_altered_response_to0.84614791
134MP0005023_abnormal_wound_healing0.84493173
135MP0001756_abnormal_urination0.83713656
136MP0000759_abnormal_skeletal_muscle0.81863545
137MP0001348_abnormal_lacrimal_gland0.80887617
138MP0000678_abnormal_parathyroid_gland0.80167313
139MP0002254_reproductive_system_inflammat0.79644342
140MP0005083_abnormal_biliary_tract0.77242723
141MP0003690_abnormal_glial_cell0.77135479
142MP0003950_abnormal_plasma_membrane0.76505462
143MP0005621_abnormal_cell_physiology0.75357658

Predicted human phenotypes

RankGene SetZ-score
1Polycythemia (HP:0001901)3.86929208
2Bundle branch block (HP:0011710)3.32798200
3Hyperglycinuria (HP:0003108)3.20159072
4Multiple enchondromatosis (HP:0005701)3.17700830
5Muscle fiber splitting (HP:0003555)3.07481784
6Vertebral compression fractures (HP:0002953)3.06024371
7Abnormality of liposaccharide metabolism (HP:0010968)2.88951867
8Abnormality of glycosphingolipid metabolism (HP:0004343)2.88951867
9Abnormality of glycolipid metabolism (HP:0010969)2.88951867
10Atrioventricular block (HP:0001678)2.88381720
11Cerebral aneurysm (HP:0004944)2.85103113
12Gout (HP:0001997)2.84952232
13Pustule (HP:0200039)2.83079598
14Arterial tortuosity (HP:0005116)2.77915186
15Hyperglycinemia (HP:0002154)2.75457798
16Distal lower limb muscle weakness (HP:0009053)2.74730776
17Vascular tortuosity (HP:0004948)2.73775172
18Difficulty climbing stairs (HP:0003551)2.71397442
19Ventricular fibrillation (HP:0001663)2.70925046
20Autoimmune thrombocytopenia (HP:0001973)2.67114348
21Abnormality of glycine metabolism (HP:0010895)2.56931487
22Abnormality of serine family amino acid metabolism (HP:0010894)2.56931487
23Posterior subcapsular cataract (HP:0007787)2.50236413
24Peritonitis (HP:0002586)2.49600971
25Distal lower limb amyotrophy (HP:0008944)2.47228722
26Global brain atrophy (HP:0002283)2.47088314
27Rhabdomyolysis (HP:0003201)2.46960089
28Progressive muscle weakness (HP:0003323)2.45401541
29Heart block (HP:0012722)2.38134359
30Ventricular tachycardia (HP:0004756)2.36491081
31Ankle contracture (HP:0006466)2.35015328
32Asymmetric septal hypertrophy (HP:0001670)2.31889104
33Amyloidosis (HP:0011034)2.31766064
34Increased variability in muscle fiber diameter (HP:0003557)2.31713890
35Abnormality of skeletal muscle fiber size (HP:0012084)2.31641698
36Abnormal atrioventricular conduction (HP:0005150)2.31379120
37Hematochezia (HP:0002573)2.28716574
38Centrally nucleated skeletal muscle fibers (HP:0003687)2.27468495
39Spondylolisthesis (HP:0003302)2.26758891
40Thin bony cortex (HP:0002753)2.24882354
41Osteolytic defects of the phalanges of the hand (HP:0009771)2.24770420
42Osteolytic defects of the hand bones (HP:0009699)2.24770420
43Premature rupture of membranes (HP:0001788)2.24178090
44Type 1 muscle fiber predominance (HP:0003803)2.23992360
45Aortic dissection (HP:0002647)2.23781586
46Syringomyelia (HP:0003396)2.23313550
47Spinal cord lesions (HP:0100561)2.23313550
48Ileus (HP:0002595)2.22577240
49Enlarged penis (HP:0000040)2.21071946
50Eczematoid dermatitis (HP:0000976)2.20346671
51Increased connective tissue (HP:0009025)2.20204665
52Abnormality of mucopolysaccharide metabolism (HP:0011020)2.19745460
53Abnormality of polysaccharide metabolism (HP:0011012)2.19745460
54Abnormality of glycosaminoglycan metabolism (HP:0004371)2.19745460
55Gingivitis (HP:0000230)2.19212599
56Abnormal cartilage morphology (HP:0002763)2.17215034
57Abnormality of the nasal mucosa (HP:0000433)2.16523051
58Right ventricular cardiomyopathy (HP:0011663)2.16112885
59Xanthomatosis (HP:0000991)2.12272186
60Achilles tendon contracture (HP:0001771)2.11820394
61Broad face (HP:0000283)2.08772278
62Microretrognathia (HP:0000308)2.08084489
63Myositis (HP:0100614)2.07985216
64Increased cerebral lipofuscin (HP:0011813)2.07920541
65Myocardial infarction (HP:0001658)2.06530707
66Abnormal platelet function (HP:0011869)2.06401447
67Impaired platelet aggregation (HP:0003540)2.06401447
68Disproportionate tall stature (HP:0001519)2.06110594
69Genu recurvatum (HP:0002816)2.05997534
70Myoglobinuria (HP:0002913)2.05726507
71Protrusio acetabuli (HP:0003179)2.05587283
72Abnormality of the Achilles tendon (HP:0005109)2.05568267
73Reduced subcutaneous adipose tissue (HP:0003758)2.05375579
74Loss of speech (HP:0002371)2.04899026
75Severe short stature (HP:0003510)2.02506993
76Fatigue (HP:0012378)1.99672919
77Blue sclerae (HP:0000592)1.98254596
78Entropion (HP:0000621)1.98009947
79Spinal rigidity (HP:0003306)1.97496128
80Exercise-induced muscle cramps (HP:0003710)1.97230838
81Orchitis (HP:0100796)1.97136133
82Rectal prolapse (HP:0002035)1.97001971
83Areflexia of lower limbs (HP:0002522)1.91422418
84Wormian bones (HP:0002645)1.91277559
85Mitral regurgitation (HP:0001653)1.90328073
86Recurrent abscess formation (HP:0002722)1.88970470
87Difficulty running (HP:0009046)1.88905675
88Fragile skin (HP:0001030)1.87905845
89Asymmetry of the thorax (HP:0001555)1.87464558
90Spontaneous hematomas (HP:0007420)1.87462935
91Deep venous thrombosis (HP:0002625)1.86691122
92Sudden death (HP:0001699)1.85997900
93Short nail (HP:0001799)1.85590182
94Petechiae (HP:0000967)1.85479395
95Flat acetabular roof (HP:0003180)1.84463083
96Dysostosis multiplex (HP:0000943)1.83952220
97Hyperacusis (HP:0010780)1.82316421
98Increased serum ferritin (HP:0003281)1.81707417
99Mitral valve prolapse (HP:0001634)1.80842501
100Gastrointestinal infarctions (HP:0005244)1.80692908
101Nasal polyposis (HP:0100582)1.79773921
102Aortic aneurysm (HP:0004942)1.79272873
103Chronic obstructive pulmonary disease (HP:0006510)1.79125482
104Obstructive lung disease (HP:0006536)1.79125482
105Absent frontal sinuses (HP:0002688)1.78563497
106Abnormality of the thoracic spine (HP:0100711)1.78390963
107Recurrent skin infections (HP:0001581)1.77991932
108Abnormality of the acetabulum (HP:0003170)1.76831467
109Abnormality of the distal phalanges of the toes (HP:0010182)1.76266694
110Systemic lupus erythematosus (HP:0002725)1.76068353
111Exercise-induced myalgia (HP:0003738)1.75547102
112Long toe (HP:0010511)1.75485683
113Atrophic scars (HP:0001075)1.75315724
114Abnormality of macrophages (HP:0004311)1.75101727
115Esophageal varix (HP:0002040)1.74193213
116Thoracic kyphosis (HP:0002942)1.74173759
117Cervical subluxation (HP:0003308)1.74104524
118Recurrent bacterial skin infections (HP:0005406)1.73445185
119Interstitial pulmonary disease (HP:0006530)1.73162417
120Ovoid vertebral bodies (HP:0003300)1.73095028
121Myopathic facies (HP:0002058)1.72317364
122Hyporeflexia of lower limbs (HP:0002600)1.72280160
123Purpura (HP:0000979)1.72208385
124Hyperammonemia (HP:0001987)1.72060551
125Papilloma (HP:0012740)1.70614314
126Verrucae (HP:0200043)1.70614314
127Bone pain (HP:0002653)1.70098298
128Recurrent fungal infections (HP:0002841)1.70061886
129Mildly elevated creatine phosphokinase (HP:0008180)1.69511430
130Ulnar deviation of the wrist (HP:0003049)1.69472505
131Upper motor neuron abnormality (HP:0002127)1.69454979
132Abnormality of proline metabolism (HP:0010907)1.69427573
133Hydroxyprolinuria (HP:0003080)1.69427573
134Abnormal ossification of hand bones (HP:0005921)1.69319730
135Abnormality of fatty-acid metabolism (HP:0004359)1.68795273
136Biconcave vertebral bodies (HP:0004586)1.68417709
137Recurrent gram-negative bacterial infections (HP:0005420)1.68393766
138Nausea (HP:0002018)1.68064173
139Frequent falls (HP:0002359)1.66638307
140Mucopolysacchariduria (HP:0008155)1.66585703
141Urinary glycosaminoglycan excretion (HP:0003541)1.66585703
142Abnormality of the peritoneum (HP:0002585)1.66282289
143Cellulitis (HP:0100658)1.65879718
144Malnutrition (HP:0004395)1.65708892
145Thoracolumbar scoliosis (HP:0002944)1.65088399
146Prolonged bleeding time (HP:0003010)1.64895242
147Reticulocytosis (HP:0001923)1.64845018
148Aneurysm (HP:0002617)1.64695931
149Slender build (HP:0001533)1.64374368
150Joint laxity (HP:0001388)1.64297640
151Segmental peripheral demyelination/remyelination (HP:0003481)1.64295920
152Abnormal platelet volume (HP:0011876)1.64070368
153Lipoatrophy (HP:0100578)1.63822638
154Abnormality of purine metabolism (HP:0004352)1.63763731
155Ulnar bowing (HP:0003031)1.63379978
156Abnormality of glutamine family amino acid metabolism (HP:0010902)1.63342329
157Gingival bleeding (HP:0000225)1.62867338
158Recurrent viral infections (HP:0004429)1.62619061
159Dilatation of the ascending aorta (HP:0005111)1.62540619
160Ventricular arrhythmia (HP:0004308)1.61839038
161Polygenic inheritance (HP:0010982)1.61585790
162Subcapsular cataract (HP:0000523)1.61548012
163Distal upper limb amyotrophy (HP:0007149)1.61441302
164Upper limb amyotrophy (HP:0009129)1.61441302
165Prominent nose (HP:0000448)1.61302963
166Hemorrhage of the eye (HP:0011885)1.61119772
167Mitral stenosis (HP:0001718)1.60895406

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB35.33845866
2PKN23.62839013
3PRPF4B2.98850184
4ERN12.93870383
5MAP3K102.51501005
6MAP4K12.46576750
7NEK22.40012505
8TTN2.28649035
9NME22.23669359
10RIPK42.19243635
11EPHB12.14683469
12SMG12.14203415
13MAP3K132.12828604
14RPS6KA42.11485325
15MAP2K32.06945754
16EEF2K2.06001874
17NEK11.93665944
18BUB11.93469891
19TAOK11.83933224
20ICK1.76875122
21IRAK31.73792603
22STK101.73221587
23LRRK21.65624757
24LMTK21.57612729
25MAP3K31.53689541
26CDK121.53136534
27MAP3K111.50741306
28TAOK31.48439334
29TYK21.45500401
30ZAP701.43970537
31EPHA21.42729670
32IRAK41.40972339
33FGFR41.38242628
34PTK61.35135792
35MAP3K141.34920947
36TBK11.33838183
37KSR21.30020976
38GRK61.20882423
39CDK41.20519488
40MAP3K81.19037007
41SIK11.17353587
42EIF2AK11.16300337
43CDC42BPA1.15732489
44KDR1.15242601
45RIPK11.15188937
46PRKD21.11028759
47ARAF1.10195501
48BCKDK1.08953443
49SCYL21.07613989
50TESK21.06069007
51MAP3K61.05312841
52ACVR1B1.05293362
53BRSK21.04433601
54DMPK1.01306765
55LATS21.00971114
56MAP2K21.00160271
57PDK30.99446642
58PDK40.99446642
59PAK40.98999949
60FGR0.98606925
61MARK30.98452308
62MAPK110.97289506
63MARK20.96884183
64NEK90.94678674
65BRSK10.89640753
66PIM20.86931702
67MOS0.86243892
68MAP3K20.85353046
69WEE10.84468133
70RPS6KA20.83646045
71PTK20.83339195
72FLT30.80656189
73BLK0.78800839
74FGFR30.77965678
75TGFBR20.77614857
76STK30.77335157
77ALK0.77135360
78STK380.76100243
79JAK30.73172909
80RET0.73112612
81ILK0.71472332
82FES0.70351382
83PDGFRA0.69055121
84PDGFRB0.69049937
85CSF1R0.68807807
86JAK20.68582235
87TESK10.68406916
88RAF10.66523724
89DDR20.66184534
90JAK10.63222892
91MAPKAPK30.62279866
92MAPK70.62039424
93ITK0.61680665
94CAMKK10.61626666
95DYRK1B0.61512386
96RPS6KL10.61476838
97RPS6KC10.61476838
98IRAK20.60216466
99KSR10.59654621
100TRPM70.56539519
101SGK30.56382174
102PDPK10.56327159
103PIM10.55443818
104MAPK120.55382513
105DYRK30.55320675
106MAP3K90.55051647
107WNK10.54772371
108MTOR0.51640025
109STK40.51209763
110PRKG20.51204288
111MAP3K50.50965528
112BMX0.50939938
113SIK30.50415905
114MYLK0.49863251
115AURKB0.49641165
116CAMK1D0.49276927
117PRKAA10.49271135
118PAK10.49192532
119PDK10.48964618
120CSK0.48753829
121YES10.48341531
122MST1R0.45476894
123LATS10.45236622
124BTK0.44937876
125MAP3K70.44743265
126PDK20.44546617
127MAPKAPK20.44291464
128PIK3CG0.43762689
129TAOK20.42793480
130MAP2K10.42498498
131MET0.42436849
132NEK60.41105395
133BRAF0.40981914
134PAK20.39490621
135CDK60.37967936
136TTK0.36989221
137MELK0.36870560
138PRKD10.36515690
139CAMKK20.36132351
140RPS6KA10.35283011
141IKBKE0.34728167
142STK240.34210661
143HCK0.33218882
144PLK10.32462713
145MAP3K10.32431518

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007503.64857454
22-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.40497068
3Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.31543006
4Pentose phosphate pathway_Homo sapiens_hsa000302.20946095
5Sulfur relay system_Homo sapiens_hsa041222.14786768
6Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.04036094
7Folate biosynthesis_Homo sapiens_hsa007902.02526213
8Carbon metabolism_Homo sapiens_hsa012001.74642906
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.73762261
10Caffeine metabolism_Homo sapiens_hsa002321.64778957
11Fatty acid degradation_Homo sapiens_hsa000711.57239325
12Biosynthesis of amino acids_Homo sapiens_hsa012301.56740730
13Fat digestion and absorption_Homo sapiens_hsa049751.53545363
14Vitamin digestion and absorption_Homo sapiens_hsa049771.50012872
15Drug metabolism - other enzymes_Homo sapiens_hsa009831.48950423
16Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.48010382
17Renal cell carcinoma_Homo sapiens_hsa052111.41076098
18Amoebiasis_Homo sapiens_hsa051461.36285168
19PPAR signaling pathway_Homo sapiens_hsa033201.32932072
20Adipocytokine signaling pathway_Homo sapiens_hsa049201.31545906
21Chronic myeloid leukemia_Homo sapiens_hsa052201.30871806
22Lysosome_Homo sapiens_hsa041421.27015448
23Focal adhesion_Homo sapiens_hsa045101.26331897
24Insulin resistance_Homo sapiens_hsa049311.25060527
25B cell receptor signaling pathway_Homo sapiens_hsa046621.22782780
26Notch signaling pathway_Homo sapiens_hsa043301.21112526
27Leishmaniasis_Homo sapiens_hsa051401.19641290
28Malaria_Homo sapiens_hsa051441.18892733
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.15859622
30Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.14714472
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.13697834
32Osteoclast differentiation_Homo sapiens_hsa043801.13505217
33mTOR signaling pathway_Homo sapiens_hsa041501.12807086
34Glycerolipid metabolism_Homo sapiens_hsa005611.12701885
35Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.10863302
36Glycerophospholipid metabolism_Homo sapiens_hsa005641.10278435
37Acute myeloid leukemia_Homo sapiens_hsa052211.07963000
38Regulation of autophagy_Homo sapiens_hsa041401.07711641
39Hepatitis C_Homo sapiens_hsa051601.07607226
40Phagosome_Homo sapiens_hsa041451.07125223
41Legionellosis_Homo sapiens_hsa051341.06931722
42TNF signaling pathway_Homo sapiens_hsa046681.05655341
43Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.04879885
44Apoptosis_Homo sapiens_hsa042101.03819638
45VEGF signaling pathway_Homo sapiens_hsa043701.03436818
46Staphylococcus aureus infection_Homo sapiens_hsa051501.02467334
47Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.02322192
48Galactose metabolism_Homo sapiens_hsa000521.01627342
49Cell cycle_Homo sapiens_hsa041101.01431432
50Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.01298924
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.99967340
52Leukocyte transendothelial migration_Homo sapiens_hsa046700.99253673
53Toxoplasmosis_Homo sapiens_hsa051450.99148352
54Regulation of actin cytoskeleton_Homo sapiens_hsa048100.98439466
55Viral myocarditis_Homo sapiens_hsa054160.98405452
56Central carbon metabolism in cancer_Homo sapiens_hsa052300.97207909
57Endocytosis_Homo sapiens_hsa041440.96756145
58Fructose and mannose metabolism_Homo sapiens_hsa000510.95309321
59Chemokine signaling pathway_Homo sapiens_hsa040620.95013634
60Adherens junction_Homo sapiens_hsa045200.94331272
61Phospholipase D signaling pathway_Homo sapiens_hsa040720.94257427
62Small cell lung cancer_Homo sapiens_hsa052220.94143917
63Salmonella infection_Homo sapiens_hsa051320.94138684
64GnRH signaling pathway_Homo sapiens_hsa049120.94072947
65Arginine biosynthesis_Homo sapiens_hsa002200.94038324
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.92978945
67p53 signaling pathway_Homo sapiens_hsa041150.91879309
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.91540076
69Nitrogen metabolism_Homo sapiens_hsa009100.90860228
70Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.90656424
71Glioma_Homo sapiens_hsa052140.89895888
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89820247
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.89274337
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.89139472
75Cysteine and methionine metabolism_Homo sapiens_hsa002700.88931577
76Pertussis_Homo sapiens_hsa051330.88375490
77Renin-angiotensin system_Homo sapiens_hsa046140.87539705
78Prion diseases_Homo sapiens_hsa050200.86741680
79RNA transport_Homo sapiens_hsa030130.86718271
80HIF-1 signaling pathway_Homo sapiens_hsa040660.86535811
81Insulin signaling pathway_Homo sapiens_hsa049100.85414597
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.84582131
83Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.84156757
84ErbB signaling pathway_Homo sapiens_hsa040120.84024873
85Tuberculosis_Homo sapiens_hsa051520.83946829
86Choline metabolism in cancer_Homo sapiens_hsa052310.83285840
87Prostate cancer_Homo sapiens_hsa052150.83230937
88Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.82765251
89ECM-receptor interaction_Homo sapiens_hsa045120.82644200
90Starch and sucrose metabolism_Homo sapiens_hsa005000.81615190
91Shigellosis_Homo sapiens_hsa051310.80157049
92Antigen processing and presentation_Homo sapiens_hsa046120.80109814
93Non-small cell lung cancer_Homo sapiens_hsa052230.79326472
94Fatty acid metabolism_Homo sapiens_hsa012120.77408467
95Inositol phosphate metabolism_Homo sapiens_hsa005620.76932861
96Glycosaminoglycan degradation_Homo sapiens_hsa005310.75959037
97NOD-like receptor signaling pathway_Homo sapiens_hsa046210.75503335
98FoxO signaling pathway_Homo sapiens_hsa040680.74913928
99RNA polymerase_Homo sapiens_hsa030200.74360928
100Thyroid cancer_Homo sapiens_hsa052160.74085002
101Phosphatidylinositol signaling system_Homo sapiens_hsa040700.73432441
102AMPK signaling pathway_Homo sapiens_hsa041520.72037423
103Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.71782083
104Colorectal cancer_Homo sapiens_hsa052100.71709467
105Other glycan degradation_Homo sapiens_hsa005110.71680863
106Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.71501555
107Estrogen signaling pathway_Homo sapiens_hsa049150.70190761
108Longevity regulating pathway - mammal_Homo sapiens_hsa042110.69713691
109MicroRNAs in cancer_Homo sapiens_hsa052060.69011364
110Pentose and glucuronate interconversions_Homo sapiens_hsa000400.67037626
111Jak-STAT signaling pathway_Homo sapiens_hsa046300.66725906
112Viral carcinogenesis_Homo sapiens_hsa052030.65829300
113Platelet activation_Homo sapiens_hsa046110.65686477
114Bile secretion_Homo sapiens_hsa049760.65597701
115Neurotrophin signaling pathway_Homo sapiens_hsa047220.65588670
116Pancreatic cancer_Homo sapiens_hsa052120.64665950
117Cyanoamino acid metabolism_Homo sapiens_hsa004600.64435145
118Mineral absorption_Homo sapiens_hsa049780.63972854
119Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63039951
120HTLV-I infection_Homo sapiens_hsa051660.63012668
121Hepatitis B_Homo sapiens_hsa051610.62754801
122Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.62726432
123Measles_Homo sapiens_hsa051620.61816457
124Hematopoietic cell lineage_Homo sapiens_hsa046400.61358624
125Primary immunodeficiency_Homo sapiens_hsa053400.60402258
126Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.60400727
127Toll-like receptor signaling pathway_Homo sapiens_hsa046200.59970911
128Endometrial cancer_Homo sapiens_hsa052130.59079598
129Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58795290
130Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.58258392
131Rap1 signaling pathway_Homo sapiens_hsa040150.57803699
132RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.57675613
133Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57573053
134Complement and coagulation cascades_Homo sapiens_hsa046100.57036569
135Propanoate metabolism_Homo sapiens_hsa006400.56963584
136T cell receptor signaling pathway_Homo sapiens_hsa046600.56778672
137Herpes simplex infection_Homo sapiens_hsa051680.55958390
138Pyrimidine metabolism_Homo sapiens_hsa002400.55445798
139Dilated cardiomyopathy_Homo sapiens_hsa054140.55397768
140DNA replication_Homo sapiens_hsa030300.54912200
141Selenocompound metabolism_Homo sapiens_hsa004500.53419615
142Epstein-Barr virus infection_Homo sapiens_hsa051690.53367861
143Pathways in cancer_Homo sapiens_hsa052000.52946648
144Proteoglycans in cancer_Homo sapiens_hsa052050.51152233
145AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.50720068
146Influenza A_Homo sapiens_hsa051640.49648181
147NF-kappa B signaling pathway_Homo sapiens_hsa040640.49557294
148Bladder cancer_Homo sapiens_hsa052190.49299379
149Prolactin signaling pathway_Homo sapiens_hsa049170.48124103

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