ZFAND1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.45695049
2maturation of SSU-rRNA (GO:0030490)4.94907151
3ribosomal small subunit biogenesis (GO:0042274)4.41462614
4mitochondrial respiratory chain complex I assembly (GO:0032981)4.23668499
5NADH dehydrogenase complex assembly (GO:0010257)4.23668499
6mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.23668499
7mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.15275375
8oxidative phosphorylation (GO:0006119)4.14285438
9daunorubicin metabolic process (GO:0044597)4.08841705
10polyketide metabolic process (GO:0030638)4.08841705
11doxorubicin metabolic process (GO:0044598)4.08841705
12viral transcription (GO:0019083)3.97240633
13energy coupled proton transport, down electrochemical gradient (GO:0015985)3.95482415
14ATP synthesis coupled proton transport (GO:0015986)3.95482415
15protein complex biogenesis (GO:0070271)3.93347580
16translational termination (GO:0006415)3.89144695
17ribosome assembly (GO:0042255)3.87243812
18cullin deneddylation (GO:0010388)3.84230379
19respiratory chain complex IV assembly (GO:0008535)3.78397345
20prenylation (GO:0097354)3.75381546
21protein prenylation (GO:0018342)3.75381546
22proteasome assembly (GO:0043248)3.71357427
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.69530114
24mitochondrial respiratory chain complex assembly (GO:0033108)3.65234399
25cotranslational protein targeting to membrane (GO:0006613)3.65047964
26viral mRNA export from host cell nucleus (GO:0046784)3.61276307
27translational elongation (GO:0006414)3.59585509
28mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.57666010
29protein targeting to ER (GO:0045047)3.55812217
30DNA double-strand break processing (GO:0000729)3.55372919
31rRNA modification (GO:0000154)3.53772291
32protein localization to endoplasmic reticulum (GO:0070972)3.47446063
33protein deneddylation (GO:0000338)3.46785338
347-methylguanosine mRNA capping (GO:0006370)3.43184147
35tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.43092893
36RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.43092893
37transcription elongation from RNA polymerase III promoter (GO:0006385)3.43034132
38termination of RNA polymerase III transcription (GO:0006386)3.43034132
39metallo-sulfur cluster assembly (GO:0031163)3.41791092
40iron-sulfur cluster assembly (GO:0016226)3.41791092
41regulation of acyl-CoA biosynthetic process (GO:0050812)3.40398991
42aerobic respiration (GO:0009060)3.39807960
43DNA deamination (GO:0045006)3.39038214
44regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.37153071
45GTP biosynthetic process (GO:0006183)3.34382298
467-methylguanosine RNA capping (GO:0009452)3.33005548
47RNA capping (GO:0036260)3.33005548
48pteridine-containing compound biosynthetic process (GO:0042559)3.32096410
49establishment of protein localization to endoplasmic reticulum (GO:0072599)3.31934559
50respiratory electron transport chain (GO:0022904)3.31292271
51deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.25846338
52dopamine transport (GO:0015872)3.25787098
53cellular component biogenesis (GO:0044085)3.24598240
54rRNA methylation (GO:0031167)3.24361304
55translation (GO:0006412)3.24243513
56regulation of mitochondrial translation (GO:0070129)3.23983411
57ribonucleoprotein complex biogenesis (GO:0022613)3.22891561
58electron transport chain (GO:0022900)3.20728560
59telomere maintenance via semi-conservative replication (GO:0032201)3.20538091
60establishment of protein localization to mitochondrial membrane (GO:0090151)3.20529759
61ribosomal large subunit biogenesis (GO:0042273)3.19630967
62branched-chain amino acid catabolic process (GO:0009083)3.19502215
63pseudouridine synthesis (GO:0001522)3.18931876
64formation of translation preinitiation complex (GO:0001731)3.18812075
65peptidyl-histidine modification (GO:0018202)3.18149687
66viral life cycle (GO:0019058)3.11797536
67CENP-A containing nucleosome assembly (GO:0034080)3.11156956
68transcription-coupled nucleotide-excision repair (GO:0006283)3.10914048
69replication fork processing (GO:0031297)3.10845846
70positive regulation of histone H3-K4 methylation (GO:0051571)3.10364197
71water-soluble vitamin biosynthetic process (GO:0042364)3.09228555
72cellular protein complex disassembly (GO:0043624)3.05282369
73L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.04933551
74exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.04821897
75regulation of centriole replication (GO:0046599)3.03607626
76cellular respiration (GO:0045333)3.03338096
77cytochrome complex assembly (GO:0017004)3.02923558
78chromatin remodeling at centromere (GO:0031055)3.02391194
79guanosine-containing compound biosynthetic process (GO:1901070)3.01370893
80regulation of cofactor metabolic process (GO:0051193)3.00721750
81regulation of coenzyme metabolic process (GO:0051196)3.00721750
82nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.98055716
83positive regulation of respiratory burst (GO:0060267)2.97852360
84translational initiation (GO:0006413)2.97128547
85regulation of sulfur metabolic process (GO:0042762)2.95504454
86GMP metabolic process (GO:0046037)2.93216855
87nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.92665103
88regulation of glucokinase activity (GO:0033131)2.91798344
89regulation of hexokinase activity (GO:1903299)2.91798344
90somatic hypermutation of immunoglobulin genes (GO:0016446)2.90949964
91somatic diversification of immune receptors via somatic mutation (GO:0002566)2.90949964
92lactate metabolic process (GO:0006089)2.90386193
93purine nucleobase biosynthetic process (GO:0009113)2.90131444
94negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.89869032
95platelet dense granule organization (GO:0060155)2.89488343
96DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.89138834
97UTP biosynthetic process (GO:0006228)2.88987995
98nucleobase biosynthetic process (GO:0046112)2.88448434
99viral protein processing (GO:0019082)2.87186162
100spliceosomal complex assembly (GO:0000245)2.86585663
101signal peptide processing (GO:0006465)2.86529445
102ribosome biogenesis (GO:0042254)2.86413015
103transcription elongation from RNA polymerase I promoter (GO:0006362)2.86368524
104signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.85393301
105signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.85393301
106signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.85393301
107CTP biosynthetic process (GO:0006241)2.84288447
108CTP metabolic process (GO:0046036)2.84288447
109aminoglycoside antibiotic metabolic process (GO:0030647)2.83910035
110intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.83649715
111signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.83649715
112UTP metabolic process (GO:0046051)2.83252604
113termination of RNA polymerase I transcription (GO:0006363)2.83243283
114regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.82988163
115regulation of oxidative phosphorylation (GO:0002082)2.81284816
116organelle disassembly (GO:1903008)2.81075128
117ether lipid metabolic process (GO:0046485)2.80938388
118establishment of integrated proviral latency (GO:0075713)2.80311879
119pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.79583292
120adenosine metabolic process (GO:0046085)2.77499507
121negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.76762642
122keratinocyte development (GO:0003334)2.76472267
123folic acid-containing compound biosynthetic process (GO:0009396)2.76453159
124pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.75310130
125thrombin receptor signaling pathway (GO:0070493)2.74185422
126signal transduction involved in DNA integrity checkpoint (GO:0072401)2.73577090
127signal transduction involved in DNA damage checkpoint (GO:0072422)2.73577090
128protein neddylation (GO:0045116)2.73408150
129amino acid salvage (GO:0043102)2.73343190
130L-methionine salvage (GO:0071267)2.73343190
131L-methionine biosynthetic process (GO:0071265)2.73343190
132telomere maintenance via recombination (GO:0000722)2.72911938
133DNA strand elongation involved in DNA replication (GO:0006271)2.72826163
134erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.72823398
135L-phenylalanine catabolic process (GO:0006559)2.72823398
136erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.71994107
137L-phenylalanine metabolic process (GO:0006558)2.71994107
138ribonucleoprotein complex disassembly (GO:0032988)2.69033966
139protein K11-linked ubiquitination (GO:0070979)2.68576730
140DNA catabolic process, exonucleolytic (GO:0000738)2.67989119
141glycerol ether metabolic process (GO:0006662)2.67661465
142histone exchange (GO:0043486)2.65404615
143reciprocal meiotic recombination (GO:0007131)2.65370859
144reciprocal DNA recombination (GO:0035825)2.65370859
145mismatch repair (GO:0006298)2.64838826
146purine-containing compound salvage (GO:0043101)2.64433150
147regulation of mitotic spindle checkpoint (GO:1903504)2.62404385
148regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.62404385
149maturation of 5.8S rRNA (GO:0000460)2.62241547
150IMP biosynthetic process (GO:0006188)2.61382597
151negative regulation of DNA-dependent DNA replication (GO:2000104)2.60139774
152somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.58744112
153somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.58744112
154isotype switching (GO:0045190)2.58744112
155methionine biosynthetic process (GO:0009086)2.57387403
156regulation of Golgi to plasma membrane protein transport (GO:0042996)2.56400899
157regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.52791846
158tRNA aminoacylation (GO:0043039)2.52043752
159amino acid activation (GO:0043038)2.52043752
160synapsis (GO:0007129)2.49470642
161mitochondrial DNA replication (GO:0006264)2.49251127
162tRNA aminoacylation for protein translation (GO:0006418)2.48796039
163positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.47975164
164ether metabolic process (GO:0018904)2.47428317
165telomere maintenance via telomerase (GO:0007004)2.47402320

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.53342481
2E2F7_22180533_ChIP-Seq_HELA_Human4.26828224
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.99398127
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.81426768
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.65243260
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.61300085
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.53342795
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.35815272
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.25654644
10RBPJ_22232070_ChIP-Seq_NCS_Mouse3.23919073
11CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.09044780
12HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.08702068
13SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.07041262
14ETS1_20019798_ChIP-Seq_JURKAT_Human3.01341176
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.85272038
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.82214855
17SRF_21415370_ChIP-Seq_HL-1_Mouse2.72490292
18MYC_18358816_ChIP-ChIP_MESCs_Mouse2.72065770
19POU3F2_20337985_ChIP-ChIP_501MEL_Human2.69691314
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.63368079
21MYC_19030024_ChIP-ChIP_MESCs_Mouse2.59134543
22PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.50744940
23EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.48527420
24MYC_19079543_ChIP-ChIP_MESCs_Mouse2.42026844
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.39396159
26VDR_23849224_ChIP-Seq_CD4+_Human2.39197952
27FOXP3_21729870_ChIP-Seq_TREG_Human2.35755977
28FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.25685605
29E2F4_17652178_ChIP-ChIP_JURKAT_Human2.21686390
30FLI1_27457419_Chip-Seq_LIVER_Mouse2.21157279
31ZFP42_18358816_ChIP-ChIP_MESCs_Mouse2.16134128
32CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.13621961
33THAP11_20581084_ChIP-Seq_MESCs_Mouse2.12060458
34HOXB4_20404135_ChIP-ChIP_EML_Mouse2.07842477
35FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse2.05836824
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.04370184
37ELK1_19687146_ChIP-ChIP_HELA_Human2.03877191
38EGR1_23403033_ChIP-Seq_LIVER_Mouse2.02785135
39CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.02069918
40VDR_22108803_ChIP-Seq_LS180_Human2.00781350
41NELFA_20434984_ChIP-Seq_ESCs_Mouse1.97532732
42XRN2_22483619_ChIP-Seq_HELA_Human1.95144008
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.94817170
44MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.93965345
45CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.93568861
46IRF1_19129219_ChIP-ChIP_H3396_Human1.92149760
47POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.90559108
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.88074232
49FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.87756792
50SOX2_18555785_ChIP-Seq_MESCs_Mouse1.85331453
51DCP1A_22483619_ChIP-Seq_HELA_Human1.79373056
52POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.78927977
53GBX2_23144817_ChIP-Seq_PC3_Human1.76854380
54CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.67302759
55GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.61345159
56TTF2_22483619_ChIP-Seq_HELA_Human1.60831522
57PADI4_21655091_ChIP-ChIP_MCF-7_Human1.60227313
58IGF1R_20145208_ChIP-Seq_DFB_Human1.59892875
59NANOG_18555785_ChIP-Seq_MESCs_Mouse1.57796181
60PCGF2_27294783_Chip-Seq_ESCs_Mouse1.54351924
61SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.53663195
62MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.51931844
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.51915777
64* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.50452184
65P300_19829295_ChIP-Seq_ESCs_Human1.46705866
66RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.46211303
67ZFP57_27257070_Chip-Seq_ESCs_Mouse1.46138697
68FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.45842342
69NOTCH1_21737748_ChIP-Seq_TLL_Human1.44059678
70AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.43154786
71ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.42830602
72HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.39736007
73GABP_19822575_ChIP-Seq_HepG2_Human1.38499961
74ZNF274_21170338_ChIP-Seq_K562_Hela1.37127938
75ER_23166858_ChIP-Seq_MCF-7_Human1.27389311
76EZH2_27294783_Chip-Seq_NPCs_Mouse1.26469299
77EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26440333
78ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.25023958
79MYCN_18555785_ChIP-Seq_MESCs_Mouse1.24511079
80TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.24040698
81MYC_18940864_ChIP-ChIP_HL60_Human1.21994022
82MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.18627929
83CIITA_25753668_ChIP-Seq_RAJI_Human1.18024990
84SUZ12_27294783_Chip-Seq_NPCs_Mouse1.17752747
85FOXM1_26456572_ChIP-Seq_MCF-7_Human1.16179116
86ZFX_18555785_ChIP-Seq_MESCs_Mouse1.15142062
87SOX17_20123909_ChIP-Seq_XEN_Mouse1.13638658
88NANOG_19829295_ChIP-Seq_ESCs_Human1.13414373
89SOX2_19829295_ChIP-Seq_ESCs_Human1.13414373
90SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12955290
91ELK1_22589737_ChIP-Seq_MCF10A_Human1.11572387
92CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.11364038
93PIAS1_25552417_ChIP-Seq_VCAP_Human1.10621502
94CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10526381
95UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.08971259
96CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.08832486
97TP53_22573176_ChIP-Seq_HFKS_Human1.08243906
98NFE2_27457419_Chip-Seq_LIVER_Mouse1.06532006
99FUS_26573619_Chip-Seq_HEK293_Human1.05383471
100EWS_26573619_Chip-Seq_HEK293_Human1.05090815
101SALL4_22934838_ChIP-ChIP_CD34+_Human1.04220554
102OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.04167524
103KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.03362903
104NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.02701662
105FOXA1_21572438_ChIP-Seq_LNCaP_Human1.02353865
106CBP_20019798_ChIP-Seq_JUKART_Human1.01690381
107IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.01690381
108CDX2_22108803_ChIP-Seq_LS180_Human1.00998597
109CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.00651406
110TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.00581321
111SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.00288573
112FOXA1_25329375_ChIP-Seq_VCAP_Human0.99388302
113FOXA1_27270436_Chip-Seq_PROSTATE_Human0.99388302
114NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.99212537
115KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.99129219
116KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.99129219
117KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.99129219
118SMAD4_21799915_ChIP-Seq_A2780_Human0.98873170
119NANOG_18555785_Chip-Seq_ESCs_Mouse0.98768796
120CRX_20693478_ChIP-Seq_RETINA_Mouse0.97300729
121P53_22387025_ChIP-Seq_ESCs_Mouse0.97212450
122STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96138379
123SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.95475884
124PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.95216488
125KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95105236
126E2F1_21310950_ChIP-Seq_MCF-7_Human0.94595211
127EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.93745853
128E2F1_18555785_Chip-Seq_ESCs_Mouse0.92409227
129AR_20517297_ChIP-Seq_VCAP_Human0.91995275
130CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.91815803
131BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.91141570
132SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.90809154
133* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.90514367
134TCF4_22108803_ChIP-Seq_LS180_Human0.90487240
135GATA1_22025678_ChIP-Seq_K562_Human0.90275171
136* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.87406290
137KDM5A_27292631_Chip-Seq_BREAST_Human0.85354374
138TAF15_26573619_Chip-Seq_HEK293_Human0.85076093
139AR_21909140_ChIP-Seq_LNCAP_Human0.82281120
140HTT_18923047_ChIP-ChIP_STHdh_Human0.78030096
141GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77128596
142POU5F1_16153702_ChIP-ChIP_HESCs_Human0.76431110
143SALL1_21062744_ChIP-ChIP_HESCs_Human0.75219101
144OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73377853
145TCF3_18692474_ChIP-Seq_MEFs_Mouse0.73356646
146FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.71963834
147SCL_19346495_ChIP-Seq_HPC-7_Human0.71901759
148SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.71089080

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis4.13696345
2MP0006292_abnormal_olfactory_placode3.81459652
3MP0009697_abnormal_copulation3.58791188
4MP0005085_abnormal_gallbladder_physiolo3.21579507
5MP0001986_abnormal_taste_sensitivity3.18350705
6MP0005365_abnormal_bile_salt2.82347661
7MP0009379_abnormal_foot_pigmentation2.68537991
8MP0002837_dystrophic_cardiac_calcinosis2.68043684
9MP0008058_abnormal_DNA_repair2.67284459
10MP0008057_abnormal_DNA_replication2.66450117
11MP0005464_abnormal_platelet_physiology2.63606396
12MP0002139_abnormal_hepatobiliary_system2.61598905
13MP0010094_abnormal_chromosome_stability2.51796360
14MP0001764_abnormal_homeostasis2.44996670
15MP0003693_abnormal_embryo_hatching2.39888104
16MP0008875_abnormal_xenobiotic_pharmacok2.38778277
17MP0004957_abnormal_blastocyst_morpholog2.16962053
18MP0010678_abnormal_skin_adnexa2.16157611
19MP0000383_abnormal_hair_follicle2.12877401
20MP0005084_abnormal_gallbladder_morpholo2.09338295
21MP0003941_abnormal_skin_development2.09215293
22MP0002396_abnormal_hematopoietic_system2.09044253
23MP0004133_heterotaxia2.07479501
24MP0002277_abnormal_respiratory_mucosa2.02930374
25MP0003186_abnormal_redox_activity1.95967516
26MP0010386_abnormal_urinary_bladder1.89673617
27MP0002938_white_spotting1.89243073
28MP0008007_abnormal_cellular_replicative1.85509842
29MP0006036_abnormal_mitochondrial_physio1.84916089
30MP0005646_abnormal_pituitary_gland1.82177227
31MP0002876_abnormal_thyroid_physiology1.77386698
32MP0002132_abnormal_respiratory_system1.77195583
33MP0003077_abnormal_cell_cycle1.75047411
34MP0002102_abnormal_ear_morphology1.74148497
35MP0005075_abnormal_melanosome_morpholog1.72772458
36MP0006035_abnormal_mitochondrial_morpho1.69632179
37MP0005360_urolithiasis1.62993476
38MP0003786_premature_aging1.62529888
39MP0000566_synostosis1.56846568
40MP0001188_hyperpigmentation1.55609270
41MP0009780_abnormal_chondrocyte_physiolo1.54041472
42MP0010234_abnormal_vibrissa_follicle1.53739488
43MP0005410_abnormal_fertilization1.52751995
44MP0004215_abnormal_myocardial_fiber1.47097005
45MP0008995_early_reproductive_senescence1.44736978
46MP0002160_abnormal_reproductive_system1.44631197
47MP0005379_endocrine/exocrine_gland_phen1.44123502
48MP0005408_hypopigmentation1.38809686
49MP0005551_abnormal_eye_electrophysiolog1.38138873
50MP0000538_abnormal_urinary_bladder1.36760205
51MP0008932_abnormal_embryonic_tissue1.33316290
52MP0002163_abnormal_gland_morphology1.32457447
53MP0005389_reproductive_system_phenotype1.30461116
54MP0003943_abnormal_hepatobiliary_system1.28560333
55MP0008789_abnormal_olfactory_epithelium1.28515508
56MP0003111_abnormal_nucleus_morphology1.27227722
57MP0005266_abnormal_metabolism1.24969313
58MP0008877_abnormal_DNA_methylation1.24281795
59MP0000358_abnormal_cell_content/1.23711128
60MP0005332_abnormal_amino_acid1.22887241
61MP0002090_abnormal_vision1.17417533
62MP0008872_abnormal_physiological_respon1.17395589
63MP0003718_maternal_effect1.16170584
64MP0001944_abnormal_pancreas_morphology1.15242536
65MP0005253_abnormal_eye_physiology1.15203825
66MP0003195_calcinosis1.15145703
67MP0003252_abnormal_bile_duct1.14416399
68MP0003121_genomic_imprinting1.12986336
69MP0000427_abnormal_hair_cycle1.10575930
70MP0008775_abnormal_heart_ventricle1.10092876
71MP0003283_abnormal_digestive_organ1.09226652
72MP0003656_abnormal_erythrocyte_physiolo1.08898486
73MP0005645_abnormal_hypothalamus_physiol1.07863742
74MP0002693_abnormal_pancreas_physiology1.07293496
75MP0001929_abnormal_gametogenesis1.04496054
76MP0004084_abnormal_cardiac_muscle1.03790148
77MP0002736_abnormal_nociception_after1.03004402
78MP0001666_abnormal_nutrient_absorption1.02079400
79MP0006054_spinal_hemorrhage1.00837417
80MP0008004_abnormal_stomach_pH1.00583438
81MP0003890_abnormal_embryonic-extraembry1.00389847
82MP0000647_abnormal_sebaceous_gland0.98424207
83MP0005220_abnormal_exocrine_pancreas0.98033431
84MP0004085_abnormal_heartbeat0.96351503
85MP0001661_extended_life_span0.95644484
86MP0001697_abnormal_embryo_size0.95574053
87MP0000013_abnormal_adipose_tissue0.95139660
88MP0000653_abnormal_sex_gland0.92653666
89MP0003123_paternal_imprinting0.92602638
90MP0001984_abnormal_olfaction0.91627066
91MP0004147_increased_porphyrin_level0.91364107
92MP0004019_abnormal_vitamin_homeostasis0.91209053
93MP0000678_abnormal_parathyroid_gland0.90987963
94MP0005395_other_phenotype0.90907042
95MP0003011_delayed_dark_adaptation0.90332105
96MP0010352_gastrointestinal_tract_polyps0.89607279
97MP0002210_abnormal_sex_determination0.88615731
98MP0001145_abnormal_male_reproductive0.88144092
99MP0000049_abnormal_middle_ear0.86314615
100MP0001905_abnormal_dopamine_level0.85305050
101MP0005376_homeostasis/metabolism_phenot0.83882005
102MP0002638_abnormal_pupillary_reflex0.83704486
103MP0001286_abnormal_eye_development0.83095746
104MP0000230_abnormal_systemic_arterial0.82756747
105MP0001119_abnormal_female_reproductive0.82370036
106MP0010329_abnormal_lipoprotein_level0.82252353
107MP0003698_abnormal_male_reproductive0.82172517
108MP0004808_abnormal_hematopoietic_stem0.81964522
109MP0005171_absent_coat_pigmentation0.80106376
110MP0000681_abnormal_thyroid_gland0.79850746
111MP0000516_abnormal_urinary_system0.79232231
112MP0005367_renal/urinary_system_phenotyp0.79232231
113MP0001529_abnormal_vocalization0.78953080
114MP0001293_anophthalmia0.78704746
115MP0009046_muscle_twitch0.77793317
116MP0000372_irregular_coat_pigmentation0.77244551
117MP0005319_abnormal_enzyme/_coenzyme0.76719471
118MP0003938_abnormal_ear_development0.74501813
119MP0006072_abnormal_retinal_apoptosis0.73032338
120MP0001919_abnormal_reproductive_system0.72080383
121MP0005409_darkened_coat_color0.71936871
122MP0005499_abnormal_olfactory_system0.71213204
123MP0005394_taste/olfaction_phenotype0.71213204
124MP0003122_maternal_imprinting0.71187843
125MP0002095_abnormal_skin_pigmentation0.70838808
126MP0001485_abnormal_pinna_reflex0.68650836
127MP0003315_abnormal_perineum_morphology0.68282233
128MP0003567_abnormal_fetal_cardiomyocyte0.68176043
129MP0000026_abnormal_inner_ear0.67446472
130MP0003787_abnormal_imprinting0.67150795
131MP0009643_abnormal_urine_homeostasis0.66757968
132MP0005503_abnormal_tendon_morphology0.66397291
133MP0000313_abnormal_cell_death0.66350708
134MP0005636_abnormal_mineral_homeostasis0.65990848
135MP0008961_abnormal_basal_metabolism0.65842845
136MP0004782_abnormal_surfactant_physiolog0.65797236
137MP0001756_abnormal_urination0.65682108
138MP0002751_abnormal_autonomic_nervous0.65128557
139MP0000631_abnormal_neuroendocrine_gland0.64542282
140MP0002009_preneoplasia0.61428827
141MP0001186_pigmentation_phenotype0.61399385
142MP0004036_abnormal_muscle_relaxation0.60379107
143MP0005174_abnormal_tail_pigmentation0.59387167

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.47278453
2Mitochondrial inheritance (HP:0001427)4.28447958
3Hepatocellular necrosis (HP:0001404)4.23150196
4Abnormal mitochondria in muscle tissue (HP:0008316)4.22418872
5Hepatic necrosis (HP:0002605)4.22022727
6Increased CSF lactate (HP:0002490)4.19056343
7Microvesicular hepatic steatosis (HP:0001414)4.01053852
8Acute encephalopathy (HP:0006846)3.94227493
9Progressive macrocephaly (HP:0004481)3.76459917
10Abnormality of cells of the erythroid lineage (HP:0012130)3.48450771
113-Methylglutaconic aciduria (HP:0003535)3.46295735
12Abnormal number of erythroid precursors (HP:0012131)3.44463187
13Cerebral edema (HP:0002181)3.42910497
14Increased hepatocellular lipid droplets (HP:0006565)3.37245483
15Increased serum lactate (HP:0002151)3.29738520
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.28343351
17Aplastic anemia (HP:0001915)3.24893895
18Generalized aminoaciduria (HP:0002909)3.16650620
19Lipid accumulation in hepatocytes (HP:0006561)3.12214813
20Reticulocytopenia (HP:0001896)3.11198506
21Lactic acidosis (HP:0003128)3.08846467
22Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.07106269
23Abnormality of alanine metabolism (HP:0010916)3.07106269
24Hyperalaninemia (HP:0003348)3.07106269
25Type I transferrin isoform profile (HP:0003642)3.03778513
26Renal Fanconi syndrome (HP:0001994)2.99225965
27Increased mean platelet volume (HP:0011877)2.97374652
28Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.92419221
29Prolonged bleeding time (HP:0003010)2.89215768
30Dyschromatopsia (HP:0007641)2.87461957
31Decreased activity of mitochondrial respiratory chain (HP:0008972)2.85243650
32Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.85243650
33Petechiae (HP:0000967)2.83447633
34Exercise intolerance (HP:0003546)2.72731859
35Hypothermia (HP:0002045)2.68379799
36Menorrhagia (HP:0000132)2.60997591
37Lethargy (HP:0001254)2.59626987
38Congenital, generalized hypertrichosis (HP:0004540)2.57685717
39Increased intramyocellular lipid droplets (HP:0012240)2.56188248
40Abnormality of urine glucose concentration (HP:0011016)2.56110466
41Glycosuria (HP:0003076)2.56110466
42Abnormality of dicarboxylic acid metabolism (HP:0010995)2.55845902
43Dicarboxylic aciduria (HP:0003215)2.55845902
44Methylmalonic acidemia (HP:0002912)2.53730115
45Birth length less than 3rd percentile (HP:0003561)2.51740600
46Medial flaring of the eyebrow (HP:0010747)2.51084947
47Abnormal platelet volume (HP:0011876)2.48038840
48Methylmalonic aciduria (HP:0012120)2.47993867
49Abnormality of glycolysis (HP:0004366)2.47958012
50Increased serum pyruvate (HP:0003542)2.47958012
51Pancreatic cysts (HP:0001737)2.47070715
52Hyperinsulinemic hypoglycemia (HP:0000825)2.46447415
53Reduced antithrombin III activity (HP:0001976)2.43559592
54Oral leukoplakia (HP:0002745)2.41290520
55Respiratory difficulties (HP:0002880)2.39900087
56Respiratory failure (HP:0002878)2.38833904
57Hypoglycemic coma (HP:0001325)2.38053413
58Pancreatic islet-cell hyperplasia (HP:0004510)2.36515043
59Hypobetalipoproteinemia (HP:0003563)2.34482225
6011 pairs of ribs (HP:0000878)2.34256445
61Chronic hepatic failure (HP:0100626)2.28395819
62Macrocytic anemia (HP:0001972)2.28156121
63Abnormality of serum amino acid levels (HP:0003112)2.25667702
64Abnormal hair whorl (HP:0010721)2.25072658
65Increased muscle lipid content (HP:0009058)2.24356575
66Abnormality of the renal cortex (HP:0011035)2.23888900
67Chromsome breakage (HP:0040012)2.23766672
68Hyperglycinemia (HP:0002154)2.22095274
69Type 2 muscle fiber atrophy (HP:0003554)2.22023740
70Renal cortical cysts (HP:0000803)2.21205167
71Biliary tract neoplasm (HP:0100574)2.20715851
72Abnormality of chromosome stability (HP:0003220)2.20504598
73Hyperglycinuria (HP:0003108)2.20438202
74Renal tubular dysfunction (HP:0000124)2.20322697
75Exertional dyspnea (HP:0002875)2.16689491
76Abnormality of the preputium (HP:0100587)2.13260314
77Acanthocytosis (HP:0001927)2.12186701
78Optic disc pallor (HP:0000543)2.12170752
79Papillary thyroid carcinoma (HP:0002895)2.11882234
80Thyroid carcinoma (HP:0002890)2.08791836
81Volvulus (HP:0002580)2.08785666
82Leukodystrophy (HP:0002415)2.06732135
83Hyperglycemia (HP:0003074)2.04957259
84Pancytopenia (HP:0001876)2.03503391
85Congenital primary aphakia (HP:0007707)2.03056380
86Aplasia/Hypoplasia of the uvula (HP:0010293)2.01898853
87Meckel diverticulum (HP:0002245)1.99469588
88Colon cancer (HP:0003003)1.99370562
89Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.98846464
90Abnormal protein N-linked glycosylation (HP:0012347)1.98846464
91Abnormal protein glycosylation (HP:0012346)1.98846464
92Abnormal glycosylation (HP:0012345)1.98846464
93Severe visual impairment (HP:0001141)1.98385594
94Abnormality of pyrimidine metabolism (HP:0004353)1.98382188
95Proximal tubulopathy (HP:0000114)1.97859395
96Abnormality of the heme biosynthetic pathway (HP:0010472)1.96783436
97Myelodysplasia (HP:0002863)1.95615092
98Tongue fasciculations (HP:0001308)1.94657015
99Pancreatic fibrosis (HP:0100732)1.94388877
100Aplasia/Hypoplasia of the fovea (HP:0008060)1.93439805
101Hypoplasia of the fovea (HP:0007750)1.93439805
102Ketoacidosis (HP:0001993)1.93235834
103Abnormality of vitamin B metabolism (HP:0004340)1.92426917
104Aplasia/hypoplasia of the uterus (HP:0008684)1.92029332
105Abnormality of methionine metabolism (HP:0010901)1.91006451
106Chromosomal breakage induced by crosslinking agents (HP:0003221)1.90710719
107Abnormality of glycine metabolism (HP:0010895)1.90344603
108Abnormality of serine family amino acid metabolism (HP:0010894)1.90344603
109Cerebral palsy (HP:0100021)1.89525470
110Nephronophthisis (HP:0000090)1.89298553
111Abnormality of secondary sexual hair (HP:0009888)1.89234557
112Abnormality of the axillary hair (HP:0100134)1.89234557
113Neuroendocrine neoplasm (HP:0100634)1.88932563
114Hyperammonemia (HP:0001987)1.88835054
115Abnormality of aspartate family amino acid metabolism (HP:0010899)1.88445094
116Abnormality of fatty-acid metabolism (HP:0004359)1.88100573
117Ketosis (HP:0001946)1.87832500
118Gait imbalance (HP:0002141)1.87396565
119CNS demyelination (HP:0007305)1.87131945
120Intestinal atresia (HP:0011100)1.86161252
121Abnormality of the ileum (HP:0001549)1.85993190
122Symptomatic seizures (HP:0011145)1.84802905
123Abnormal hemoglobin (HP:0011902)1.84665983
124Breast hypoplasia (HP:0003187)1.84594319
125Nephrogenic diabetes insipidus (HP:0009806)1.84130558
126Abnormality of renal resorption (HP:0011038)1.83446268
127Long foot (HP:0001833)1.82924273
128Molar tooth sign on MRI (HP:0002419)1.81758829
129Abnormality of midbrain morphology (HP:0002418)1.81758829
130Abnormal biliary tract morphology (HP:0012440)1.81613299
131Facial cleft (HP:0002006)1.81382185
132Intrahepatic cholestasis (HP:0001406)1.81185631
133Abnormality of aromatic amino acid family metabolism (HP:0004338)1.81092045
134True hermaphroditism (HP:0010459)1.77270057
135Hypoplasia of the uterus (HP:0000013)1.75324558
136Metaphyseal dysplasia (HP:0100255)1.73851763
137Vomiting (HP:0002013)1.73319681
138Hyperlipoproteinemia (HP:0010980)1.72974095
139Palpitations (HP:0001962)1.72803761
140Decreased central vision (HP:0007663)1.71717906
141Muscle fiber atrophy (HP:0100295)1.71397684
142Megaloblastic anemia (HP:0001889)1.71329416
143Abnormal spermatogenesis (HP:0008669)1.69729155
144Abnormality of the pancreatic islet cells (HP:0006476)1.68655032
145Abnormality of endocrine pancreas physiology (HP:0012093)1.68655032
146Abnormality of the pons (HP:0007361)1.68330032
147Hypoglycemic seizures (HP:0002173)1.68162888
148Genital tract atresia (HP:0001827)1.67665015
149Abnormality of the fovea (HP:0000493)1.67084477
150Ovarian neoplasm (HP:0100615)1.65352518
151Tinnitus (HP:0000360)1.62759710

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK3.59720641
2STK163.45161395
3ZAK3.04445139
4INSRR2.99968245
5SRPK12.65701710
6NEK12.37479294
7TRIM282.35902829
8BUB12.31613205
9VRK12.27986927
10TSSK62.21536675
11NUAK12.21105946
12SIK32.21076855
13WEE12.14129133
14BCR2.04415442
15PBK1.99637588
16EIF2AK31.97477993
17CASK1.89500676
18STK31.85537185
19EIF2AK11.84795625
20PASK1.79456614
21FRK1.70376634
22MKNK11.69578191
23TNIK1.64027457
24MYLK1.62909482
25MAP4K21.61758572
26ACVR1B1.60913652
27TGFBR11.59428824
28IRAK31.52072675
29MAP3K121.51855054
30CCNB11.51801798
31STK38L1.45063368
32VRK21.45004895
33CDK81.43961639
34FLT31.40791692
35MAP3K41.39382161
36AKT31.38822866
37BMPR1B1.36465229
38STK391.35772458
39STK241.32016017
40IRAK41.29340357
41RPS6KB21.26910838
42TEC1.25836999
43MAPK151.25088476
44TAF11.24703653
45EIF2AK21.24479471
46NME11.22726170
47PLK31.17355050
48YES11.15291430
49CDK191.12809019
50GRK71.12638762
51BRD41.12473638
52ERBB31.09753693
53CDC71.07373122
54BMPR20.99038954
55NME20.98233720
56TAOK30.97811284
57ATR0.97550897
58BRSK20.95613734
59OBSCN0.95059309
60EPHA20.91519965
61ILK0.86523467
62LATS10.83731698
63WNK40.83048013
64ADRBK20.82241241
65CDK70.81741522
66TLK10.80997584
67PRKCE0.78368023
68MAP2K70.76857921
69MAP2K60.76719218
70PTK2B0.76176378
71AURKB0.74363899
72MST1R0.73763390
73PDK30.73372057
74PDK40.73372057
75PLK40.73007838
76DYRK20.72771068
77PINK10.71327889
78MAPKAPK50.71094752
79SCYL20.70753969
80PLK10.68138072
81BRSK10.66318332
82CSNK2A10.65539168
83EPHA30.64711049
84FER0.64676482
85PAK30.64474102
86IRAK10.62967904
87TXK0.62635464
88NEK90.62594782
89TTK0.62564429
90PIM20.62445299
91BMX0.61239412
92AURKA0.61187589
93CSNK2A20.58521190
94CDK30.58201766
95MST40.56156332
96CSNK1G30.55857677
97TGFBR20.54023221
98DAPK10.53525588
99ATM0.53448874
100RPS6KA40.52232200
101SGK20.50835057
102WNK30.50274306
103TNK20.49198563
104PIK3CG0.48268380
105NEK60.47715072
106FGFR20.47687793
107PHKG20.47304624
108PHKG10.47304624
109DYRK30.46845816
110FGFR10.46282108
111PNCK0.45761034
112TRPM70.45522786
113BTK0.45434477
114PLK20.44937157
115IKBKB0.44930101
116RPS6KA50.44916091
117GRK10.44500945
118CHEK20.43911687
119MKNK20.43467622
120NLK0.42496218
121NTRK30.41735712
122CSNK1G10.41138873
123CSF1R0.40114927
124PRKCG0.38948461
125RPS6KB10.38146421
126STK40.38040279
127MET0.37989395
128MAPK130.37579020
129MUSK0.37403007
130GRK50.36720389
131TIE10.36121553
132CSNK1G20.34828964
133CSNK1A1L0.34799296
134OXSR10.34567579
135MAP3K30.32954225
136PIM10.32891779
137CSNK1E0.32879990
138PRKCI0.25870566

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.91979935
2Proteasome_Homo sapiens_hsa030502.90060026
3RNA polymerase_Homo sapiens_hsa030202.81755716
4Oxidative phosphorylation_Homo sapiens_hsa001902.80213514
5DNA replication_Homo sapiens_hsa030302.77142088
6Mismatch repair_Homo sapiens_hsa034302.68485844
7Parkinsons disease_Homo sapiens_hsa050122.50211736
8Pyrimidine metabolism_Homo sapiens_hsa002402.12185635
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.08691057
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.02718809
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.00183366
12Homologous recombination_Homo sapiens_hsa034401.91204570
13Protein export_Homo sapiens_hsa030601.90684789
14Spliceosome_Homo sapiens_hsa030401.90468442
15Non-homologous end-joining_Homo sapiens_hsa034501.88949300
16Base excision repair_Homo sapiens_hsa034101.88360589
17Propanoate metabolism_Homo sapiens_hsa006401.85000591
18Nucleotide excision repair_Homo sapiens_hsa034201.81976162
19Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.78342563
20One carbon pool by folate_Homo sapiens_hsa006701.76120136
21Huntingtons disease_Homo sapiens_hsa050161.74570372
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.72257708
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.63693124
24Basal transcription factors_Homo sapiens_hsa030221.56842772
25Alzheimers disease_Homo sapiens_hsa050101.56728991
26Fatty acid elongation_Homo sapiens_hsa000621.54864761
27Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.52776184
28Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.50939068
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.49370691
30RNA degradation_Homo sapiens_hsa030181.48933183
31Peroxisome_Homo sapiens_hsa041461.46149293
32Nitrogen metabolism_Homo sapiens_hsa009101.42554760
33Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.42328105
34Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.38014802
35Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.37992528
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.36638032
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.30935636
38Chemical carcinogenesis_Homo sapiens_hsa052041.30920046
39Primary bile acid biosynthesis_Homo sapiens_hsa001201.29607996
40Glutathione metabolism_Homo sapiens_hsa004801.29523373
41Purine metabolism_Homo sapiens_hsa002301.28747316
42RNA transport_Homo sapiens_hsa030131.28632790
43Pyruvate metabolism_Homo sapiens_hsa006201.28054840
44Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.27356648
45Fanconi anemia pathway_Homo sapiens_hsa034601.26487923
46Pentose and glucuronate interconversions_Homo sapiens_hsa000401.24394612
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.22810837
48beta-Alanine metabolism_Homo sapiens_hsa004101.21010765
49Maturity onset diabetes of the young_Homo sapiens_hsa049501.18401540
50Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.17622049
51Carbon metabolism_Homo sapiens_hsa012001.16596515
52Sulfur metabolism_Homo sapiens_hsa009201.16476306
53Cyanoamino acid metabolism_Homo sapiens_hsa004601.15370494
54Phototransduction_Homo sapiens_hsa047441.13633897
55Fatty acid degradation_Homo sapiens_hsa000711.09941813
56Butanoate metabolism_Homo sapiens_hsa006501.08374017
57Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.06987501
58Folate biosynthesis_Homo sapiens_hsa007901.06265167
59Sulfur relay system_Homo sapiens_hsa041221.04907981
60Phenylalanine metabolism_Homo sapiens_hsa003601.04261720
61Cysteine and methionine metabolism_Homo sapiens_hsa002701.01487850
62Tryptophan metabolism_Homo sapiens_hsa003800.99285693
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99156061
64Tyrosine metabolism_Homo sapiens_hsa003500.95711497
65Cell cycle_Homo sapiens_hsa041100.91047041
66Steroid hormone biosynthesis_Homo sapiens_hsa001400.89831576
67Metabolic pathways_Homo sapiens_hsa011000.89654443
68Retinol metabolism_Homo sapiens_hsa008300.89260151
69Biosynthesis of amino acids_Homo sapiens_hsa012300.88813242
70Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87001675
71Circadian rhythm_Homo sapiens_hsa047100.83131620
72Histidine metabolism_Homo sapiens_hsa003400.77596225
73Oocyte meiosis_Homo sapiens_hsa041140.76515461
74Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75499926
75Caffeine metabolism_Homo sapiens_hsa002320.74379470
76Vitamin B6 metabolism_Homo sapiens_hsa007500.73297815
77Arachidonic acid metabolism_Homo sapiens_hsa005900.69627364
78Olfactory transduction_Homo sapiens_hsa047400.68493645
79Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.66985648
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66879476
81Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.62938889
82Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.61655976
83Pentose phosphate pathway_Homo sapiens_hsa000300.60373611
84Collecting duct acid secretion_Homo sapiens_hsa049660.59575005
85Fatty acid metabolism_Homo sapiens_hsa012120.59234111
86Steroid biosynthesis_Homo sapiens_hsa001000.55504998
87Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.54754383
88Platelet activation_Homo sapiens_hsa046110.53962602
89mRNA surveillance pathway_Homo sapiens_hsa030150.53801957
90Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.50330977
91Selenocompound metabolism_Homo sapiens_hsa004500.50188111
92p53 signaling pathway_Homo sapiens_hsa041150.49617043
93Arginine and proline metabolism_Homo sapiens_hsa003300.47778969
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.46793504
95Cardiac muscle contraction_Homo sapiens_hsa042600.45843508
96Serotonergic synapse_Homo sapiens_hsa047260.45252252
97Fructose and mannose metabolism_Homo sapiens_hsa000510.43932040
98Alcoholism_Homo sapiens_hsa050340.42712628
99Ether lipid metabolism_Homo sapiens_hsa005650.41661672
100Linoleic acid metabolism_Homo sapiens_hsa005910.40534257
101Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.40392662
102Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.37106865
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36851164
104N-Glycan biosynthesis_Homo sapiens_hsa005100.36755665
105Vitamin digestion and absorption_Homo sapiens_hsa049770.36198258
106Fat digestion and absorption_Homo sapiens_hsa049750.35244424
107Regulation of autophagy_Homo sapiens_hsa041400.35159824
108Galactose metabolism_Homo sapiens_hsa000520.33877400
109Complement and coagulation cascades_Homo sapiens_hsa046100.33747396
110Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.32615205
111Pancreatic secretion_Homo sapiens_hsa049720.31793747
112Starch and sucrose metabolism_Homo sapiens_hsa005000.31094643
113Epstein-Barr virus infection_Homo sapiens_hsa051690.30187879
114Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.30123957
115Glycerolipid metabolism_Homo sapiens_hsa005610.30078376
116Vibrio cholerae infection_Homo sapiens_hsa051100.27607726
117ABC transporters_Homo sapiens_hsa020100.27371279
118Sphingolipid metabolism_Homo sapiens_hsa006000.25762749
119Systemic lupus erythematosus_Homo sapiens_hsa053220.22784405
120SNARE interactions in vesicular transport_Homo sapiens_hsa041300.21025379

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