ZFC3H1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1histone H3-K4 trimethylation (GO:0080182)4.85209644
2regulation of histone H3-K27 methylation (GO:0061085)4.67105848
3NIK/NF-kappaB signaling (GO:0038061)4.58201785
4positive regulation of gamma-delta T cell activation (GO:0046645)4.27835153
5definitive hemopoiesis (GO:0060216)4.18604262
6antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.87999441
7monoubiquitinated protein deubiquitination (GO:0035520)3.81710097
8cytoplasmic mRNA processing body assembly (GO:0033962)3.76398464
9regulation of interleukin-12 biosynthetic process (GO:0045075)3.66983077
10histone H3-K4 methylation (GO:0051568)3.66782406
11protein localization to Golgi apparatus (GO:0034067)3.62535784
12phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.60911275
13interkinetic nuclear migration (GO:0022027)3.59003921
14nuclear pore organization (GO:0006999)3.58871735
15negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.57139967
16negative regulation of cell killing (GO:0031342)3.57139967
17pore complex assembly (GO:0046931)3.48050093
18peptidyl-lysine trimethylation (GO:0018023)3.47875344
19growth hormone receptor signaling pathway (GO:0060396)3.45855043
20negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.39162284
21negative regulation of translation, ncRNA-mediated (GO:0040033)3.39162284
22regulation of translation, ncRNA-mediated (GO:0045974)3.39162284
23sperm motility (GO:0030317)3.33519513
24cellular response to ethanol (GO:0071361)3.29392243
25B cell receptor signaling pathway (GO:0050853)3.26685227
26regulation of protein polyubiquitination (GO:1902914)3.25588722
27single strand break repair (GO:0000012)3.21926199
28regulation of gamma-delta T cell activation (GO:0046643)3.19097279
29regulation of gamma-delta T cell differentiation (GO:0045586)3.09028957
30lipid translocation (GO:0034204)3.08662023
31phospholipid translocation (GO:0045332)3.08662023
32negative T cell selection (GO:0043383)3.07028825
33negative thymic T cell selection (GO:0045060)3.05882201
34cilium or flagellum-dependent cell motility (GO:0001539)3.02322200
35cellular response to growth hormone stimulus (GO:0071378)2.99463208
36DNA packaging (GO:0006323)2.98403619
37histone H3-K36 demethylation (GO:0070544)2.98005154
38positive regulation of natural killer cell differentiation (GO:0032825)2.96115161
39regulation of B cell differentiation (GO:0045577)2.94866473
40acrosome reaction (GO:0007340)2.94753109
41response to muramyl dipeptide (GO:0032495)2.94554150
42I-kappaB phosphorylation (GO:0007252)2.94020841
43mitotic sister chromatid cohesion (GO:0007064)2.91182169
44negative regulation of histone methylation (GO:0031061)2.90856954
45T-helper cell differentiation (GO:0042093)2.88511838
46CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.88511838
47cellular extravasation (GO:0045123)2.88257916
48Golgi to endosome transport (GO:0006895)2.87263948
49centrosome duplication (GO:0051298)2.86465240
50positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.86367867
51microtubule nucleation (GO:0007020)2.85613280
52protein K48-linked deubiquitination (GO:0071108)2.85199404
53positive thymic T cell selection (GO:0045059)2.83967964
54cell wall macromolecule catabolic process (GO:0016998)2.83833846
55chromosome condensation (GO:0030261)2.83652781
56regulation of establishment of cell polarity (GO:2000114)2.81613641
57positive regulation of Rab GTPase activity (GO:0032851)2.81578666
58regulation of Rab GTPase activity (GO:0032313)2.81578666
59histone mRNA catabolic process (GO:0071044)2.81101961
60natural killer cell mediated immunity (GO:0002228)2.79245353
61natural killer cell mediated cytotoxicity (GO:0042267)2.79245353
62histone lysine methylation (GO:0034968)2.78425794
63regulation of RNA export from nucleus (GO:0046831)2.77650312
64positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.77234823
65negative regulation of granulocyte differentiation (GO:0030853)2.76822388
66response to interleukin-15 (GO:0070672)2.75523546
67regulation of histone methylation (GO:0031060)2.74132710
68regulation of interferon-beta biosynthetic process (GO:0045357)2.73485585
69RNA destabilization (GO:0050779)2.71954568
70positive regulation of protein import into nucleus, translocation (GO:0033160)2.70421203
71positive regulation of p38MAPK cascade (GO:1900745)2.68325488
72positive T cell selection (GO:0043368)2.68067802
73peptidyl-lysine methylation (GO:0018022)2.67919346
74negative regulation of T cell mediated immunity (GO:0002710)2.67736232
75negative regulation of erythrocyte differentiation (GO:0045647)2.66598684
76regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.66248613
77mast cell activation (GO:0045576)2.65747659
78positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.64590736
79intra-Golgi vesicle-mediated transport (GO:0006891)2.64585642
80B cell homeostasis (GO:0001782)2.61366673
81megakaryocyte development (GO:0035855)2.59321506
82regulation of DNA methylation (GO:0044030)2.57912008
83necrotic cell death (GO:0070265)2.57836533
84retrograde transport, vesicle recycling within Golgi (GO:0000301)2.57743142
85T cell differentiation involved in immune response (GO:0002292)2.56688868
86alpha-beta T cell differentiation involved in immune response (GO:0002293)2.56688868
87alpha-beta T cell activation involved in immune response (GO:0002287)2.56688868
88negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.56537983
89negative regulation of T-helper cell differentiation (GO:0045623)2.56537983
90protein dealkylation (GO:0008214)2.56314103
91protein demethylation (GO:0006482)2.56314103
92T cell selection (GO:0045058)2.55835502
93nuclear pore complex assembly (GO:0051292)2.55766697
94nucleus organization (GO:0006997)2.55697073
95regulation of histone H3-K9 methylation (GO:0051570)2.55354852
96germinal center formation (GO:0002467)2.53799141
97macrophage activation involved in immune response (GO:0002281)2.53122881
98positive regulation of B cell differentiation (GO:0045579)2.52757322
99histone H3-K9 modification (GO:0061647)2.51962851
100regulation of T cell tolerance induction (GO:0002664)2.51588465
101cell wall macromolecule metabolic process (GO:0044036)2.50809581
102neutrophil activation (GO:0042119)2.50638147
103centriole replication (GO:0007099)2.50357252
104histone H3-K9 methylation (GO:0051567)2.48704246
105thymic T cell selection (GO:0045061)2.48008432
106positive regulation of interferon-alpha production (GO:0032727)2.47233037
107peptidyl-lysine dimethylation (GO:0018027)2.46755327
108histone H3-K9 demethylation (GO:0033169)2.45395268
109poly(A)+ mRNA export from nucleus (GO:0016973)2.44998312
110NLS-bearing protein import into nucleus (GO:0006607)2.44603366
111natural killer cell differentiation (GO:0001779)2.44458069
112histone lysine demethylation (GO:0070076)2.43271078
113positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.42731103
114antigen processing and presentation of endogenous antigen (GO:0019883)2.42226167
115regulation of germinal center formation (GO:0002634)2.41815865
116regulation of necroptotic process (GO:0060544)2.41068252
117striated muscle atrophy (GO:0014891)2.35971289
118CD4-positive, alpha-beta T cell differentiation (GO:0043367)2.33530051
119positive regulation of cellular amide metabolic process (GO:0034250)2.33524743
120early endosome to late endosome transport (GO:0045022)2.32800782
121insulin-like growth factor receptor signaling pathway (GO:0048009)2.32191412
122regulation of integrin activation (GO:0033623)2.31449303
123myeloid dendritic cell activation (GO:0001773)2.31392218
124antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.29042181
125antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.29042181
126granulocyte activation (GO:0036230)2.28736151
127histone demethylation (GO:0016577)2.28137078
128myeloid dendritic cell differentiation (GO:0043011)2.27653062
129phospholipid homeostasis (GO:0055091)2.27232020
130neutrophil mediated immunity (GO:0002446)2.27222460
131muscle atrophy (GO:0014889)2.23958564
132positive regulation by symbiont of host defense response (GO:0052509)2.23052032
133modulation by symbiont of host defense response (GO:0052031)2.23052032
134modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.23052032
135modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.23052032
136positive regulation by organism of defense response of other organism involved in symbiotic interact2.23052032
137modulation by symbiont of host immune response (GO:0052553)2.23052032
138positive regulation of natural killer cell activation (GO:0032816)2.19614216
139positive regulation of histone deacetylation (GO:0031065)2.18546878
140necroptotic process (GO:0070266)2.16224152
141regulation of granulocyte differentiation (GO:0030852)2.15944183
142establishment of protein localization to Golgi (GO:0072600)2.14750662
143regulation of dendritic cell antigen processing and presentation (GO:0002604)2.14516239
144myeloid leukocyte mediated immunity (GO:0002444)2.14011303
145embryonic retina morphogenesis in camera-type eye (GO:0060059)2.13564216
146regulation of RIG-I signaling pathway (GO:0039535)2.13543972
147neutrophil activation involved in immune response (GO:0002283)2.13033237
148negative regulation of alpha-beta T cell activation (GO:0046636)2.11406338
149JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.11235927
150positive regulation of granulocyte differentiation (GO:0030854)2.10992492
151protein targeting to Golgi (GO:0000042)2.10823860
152embryonic hemopoiesis (GO:0035162)2.10300652
153regulation of B cell receptor signaling pathway (GO:0050855)2.08356916
154mature B cell differentiation (GO:0002335)2.07605256
155positive regulation of cholesterol efflux (GO:0010875)2.07588609
156skeletal muscle adaptation (GO:0043501)2.06893199
157positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.06886362

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.59209433
2STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.65220159
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.13416072
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.97268195
5SMAD_19615063_ChIP-ChIP_OVARY_Human2.93332900
6EGR1_19374776_ChIP-ChIP_THP-1_Human2.76810130
7STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.45618908
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.38163060
9IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.28806577
10VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.26010884
11* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.19291980
12Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.17308606
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.11412178
14IRF8_27001747_Chip-Seq_BMDM_Mouse2.11243989
15GATA1_22025678_ChIP-Seq_K562_Human2.10728978
16RUNX_20019798_ChIP-Seq_JUKART_Human2.08631614
17STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.88969324
18FUS_26573619_Chip-Seq_HEK293_Human1.85560556
19NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.85267621
20FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.81611839
21TP53_16413492_ChIP-PET_HCT116_Human1.78953882
22ZNF217_24962896_ChIP-Seq_MCF-7_Human1.78485894
23SALL1_21062744_ChIP-ChIP_HESCs_Human1.77838057
24POU3F2_20337985_ChIP-ChIP_501MEL_Human1.74590061
25RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.71440837
26IRF8_21731497_ChIP-ChIP_J774_Mouse1.68863516
27MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.68784942
28TP63_19390658_ChIP-ChIP_HaCaT_Human1.66903974
29PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.58833510
30VDR_24787735_ChIP-Seq_THP-1_Human1.57285417
31ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.52128353
32AHR_22903824_ChIP-Seq_MCF-7_Human1.50511559
33SCL_19346495_ChIP-Seq_HPC-7_Human1.49128136
34ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.48281103
35IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48191513
36CBP_20019798_ChIP-Seq_JUKART_Human1.48191513
37* TCF7_22412390_ChIP-Seq_EML_Mouse1.47135390
38ER_23166858_ChIP-Seq_MCF-7_Human1.46777610
39IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.46519213
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.45161586
41GATA2_21666600_ChIP-Seq_HMVEC_Human1.44338345
42GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.42553715
43MYB_21317192_ChIP-Seq_ERMYB_Mouse1.39881601
44FOXO3_23340844_ChIP-Seq_DLD1_Human1.38304041
45AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.35415288
46ARNT_22903824_ChIP-Seq_MCF-7_Human1.32980271
47TP63_17297297_ChIP-ChIP_HaCaT_Human1.31937092
48MYB_26560356_Chip-Seq_TH1_Human1.31927436
49SPI1_23127762_ChIP-Seq_K562_Human1.28847231
50KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.28587792
51GATA3_26560356_Chip-Seq_TH2_Human1.28019870
52RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.27905818
53MYB_26560356_Chip-Seq_TH2_Human1.25961507
54GATA1_19941826_ChIP-Seq_K562_Human1.25839100
55TAF15_26573619_Chip-Seq_HEK293_Human1.22602546
56FOXA2_19822575_ChIP-Seq_HepG2_Human1.22326607
57UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.21747589
58CTNNB1_20460455_ChIP-Seq_HCT116_Human1.20748303
59VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.19425729
60CDX2_19796622_ChIP-Seq_MESCs_Mouse1.19344726
61GATA2_19941826_ChIP-Seq_K562_Human1.19111236
62* PU_27001747_Chip-Seq_BMDM_Mouse1.16249132
63PRDM14_20953172_ChIP-Seq_ESCs_Human1.16119361
64DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15111501
65FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.14464020
66CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.13765764
67BRD4_27068464_Chip-Seq_AML-cells_Mouse1.13724045
68ESR1_21235772_ChIP-Seq_MCF-7_Human1.12808823
69FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.11274400
70TCF4_18268006_ChIP-ChIP_LS174T_Human1.09820867
71PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.09695598
72FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.09502675
73VDR_22108803_ChIP-Seq_LS180_Human1.08321549
74RXR_22108803_ChIP-Seq_LS180_Human1.07272955
75GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07102640
76MAF_26560356_Chip-Seq_TH1_Human1.06655272
77BRD4_25478319_ChIP-Seq_HGPS_Human1.06442512
78SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.05621398
79SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.05621398
80PPAR_26484153_Chip-Seq_NCI-H1993_Human1.04786462
81NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.03819674
82SMRT_27268052_Chip-Seq_Bcells_Human1.03778288
83SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.03408174
84AR_21572438_ChIP-Seq_LNCaP_Human1.02280003
85NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.02262229
86KDM2B_26808549_Chip-Seq_DND41_Human1.01767918
87MYC_22102868_ChIP-Seq_BL_Human1.01253987
88CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99557263
89* TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.99044834
90SPI1_23547873_ChIP-Seq_NB4_Human0.98802888
91DROSHA_22980978_ChIP-Seq_HELA_Human0.98695731
92PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.97915853
93FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.97502286
94TP63_23658742_ChIP-Seq_EP156T_Human0.97411756
95* FLI1_21867929_ChIP-Seq_TH2_Mouse0.97023501
96TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.96415451
97GBX2_23144817_ChIP-Seq_PC3_Human0.95979567
98KDM2B_26808549_Chip-Seq_SUP-B15_Human0.95863057
99MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95349848
100FOXM1_26456572_ChIP-Seq_MCF-7_Human0.95015517
101SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94863605
102KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.94729821
103TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94722163
104POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.94722163
105RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.94124516
106TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.94085281
107STAT3_23295773_ChIP-Seq_U87_Human0.94020373
108VDR_24763502_ChIP-Seq_THP-1_Human0.93700187
109* SOX9_24532713_ChIP-Seq_HFSC_Mouse0.92993166
110* KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.92876268
111GATA3_27048872_Chip-Seq_THYMUS_Human0.92202617
112BP1_19119308_ChIP-ChIP_Hs578T_Human0.92199226
113NFIB_24661679_ChIP-Seq_LUNG_Mouse0.91973032
114CJUN_26792858_Chip-Seq_BT549_Human0.91641289
115TBL1_22424771_ChIP-Seq_293T_Human0.90714690
116CTBP2_25329375_ChIP-Seq_LNCAP_Human0.89803183
117GATA1_19941827_ChIP-Seq_MEL86_Mouse0.89300602
118KDM2B_26808549_Chip-Seq_JURKAT_Human0.88922365
119CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.88824322
120STAT4_19710469_ChIP-ChIP_TH1__Mouse0.88426383
121* ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.88355210
122ISL1_27105846_Chip-Seq_CPCs_Mouse0.87761675
123PCGF2_27294783_Chip-Seq_NPCs_Mouse0.87726215
124* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87154159
125TCF4_23295773_ChIP-Seq_U87_Human0.86479052
126TP53_18474530_ChIP-ChIP_U2OS_Human0.86302892
127ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.86268868
128TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.86068519
129NANOG_18555785_Chip-Seq_ESCs_Mouse0.85205250
130TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.85114905
131E2F1_18555785_Chip-Seq_ESCs_Mouse0.84680192
132E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.84630724
133WT1_25993318_ChIP-Seq_PODOCYTE_Human0.84608674
134SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.83954562
135GATA3_26560356_Chip-Seq_TH1_Human0.83892905
136ESR1_20079471_ChIP-ChIP_T-47D_Human0.83892834
137SMAD4_21799915_ChIP-Seq_A2780_Human0.83257810

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation7.71028482
2MP0002254_reproductive_system_inflammat3.56964464
3MP0005410_abnormal_fertilization3.36639767
4MP0002166_altered_tumor_susceptibility3.24940914
5MP0001835_abnormal_antigen_presentation2.81619395
6MP0003787_abnormal_imprinting2.79240273
7MP0002138_abnormal_hepatobiliary_system2.67048939
8MP0005076_abnormal_cell_differentiation2.58675509
9MP0002009_preneoplasia2.55246891
10MP0002006_tumorigenesis2.40330970
11MP0003300_gastrointestinal_ulcer2.40098986
12MP0008995_early_reproductive_senescence2.32379464
13MP0005174_abnormal_tail_pigmentation2.18750757
14MP0000685_abnormal_immune_system2.16045635
15MP0002396_abnormal_hematopoietic_system2.14816525
16MP0004510_myositis2.12323613
17MP0001873_stomach_inflammation2.03332086
18MP0003045_fibrosis2.01726867
19MP0010352_gastrointestinal_tract_polyps1.98526243
20MP0001800_abnormal_humoral_immune1.93488316
21MP0005671_abnormal_response_to1.84936750
22MP0001790_abnormal_immune_system1.83447146
23MP0005387_immune_system_phenotype1.83447146
24MP0000371_diluted_coat_color1.80339948
25MP0003705_abnormal_hypodermis_morpholog1.78330892
26MP0005451_abnormal_body_composition1.72847242
27MP0003252_abnormal_bile_duct1.71978338
28MP0001348_abnormal_lacrimal_gland1.71856050
29MP0003656_abnormal_erythrocyte_physiolo1.67587125
30MP0004808_abnormal_hematopoietic_stem1.66902714
31MP0003172_abnormal_lysosome_physiology1.66838861
32MP0002452_abnormal_antigen_presenting1.65630989
33MP0003091_abnormal_cell_migration1.59894019
34MP0000015_abnormal_ear_pigmentation1.57048851
35MP0002723_abnormal_immune_serum1.47822180
36MP0002419_abnormal_innate_immunity1.45607259
37MP0010307_abnormal_tumor_latency1.43898599
38MP0003436_decreased_susceptibility_to1.42884040
39MP0003724_increased_susceptibility_to1.42013012
40MP0001819_abnormal_immune_cell1.40560470
41MP0002420_abnormal_adaptive_immunity1.40473668
42MP0008004_abnormal_stomach_pH1.40227109
43MP0001879_abnormal_lymphatic_vessel1.38989905
44MP0002928_abnormal_bile_duct1.38632578
45MP0003303_peritoneal_inflammation1.36170034
46MP0009115_abnormal_fat_cell1.33382751
47MP0002398_abnormal_bone_marrow1.31135804
48MP0003698_abnormal_male_reproductive1.31046101
49MP0005000_abnormal_immune_tolerance1.31038290
50MP0001929_abnormal_gametogenesis1.30416330
51MP0010234_abnormal_vibrissa_follicle1.28419994
52MP0003566_abnormal_cell_adhesion1.28091440
53MP0001851_eye_inflammation1.28017942
54MP0004947_skin_inflammation1.23100966
55MP0004264_abnormal_extraembryonic_tissu1.22457397
56MP0003763_abnormal_thymus_physiology1.21493799
57MP0003183_abnormal_peptide_metabolism1.20719410
58MP0009278_abnormal_bone_marrow1.20469155
59MP0002132_abnormal_respiratory_system1.20161435
60MP0005310_abnormal_salivary_gland1.17964879
61MP0000716_abnormal_immune_system1.17865728
62MP0005397_hematopoietic_system_phenotyp1.17601273
63MP0001545_abnormal_hematopoietic_system1.17601273
64MP0005464_abnormal_platelet_physiology1.15615719
65MP0008877_abnormal_DNA_methylation1.12913877
66MP0010155_abnormal_intestine_physiology1.12560893
67MP0000733_abnormal_muscle_development1.10250698
68MP0002405_respiratory_system_inflammati1.08301963
69MP0000767_abnormal_smooth_muscle1.07529142
70MP0000703_abnormal_thymus_morphology1.05616151
71MP0004883_abnormal_blood_vessel1.04645227
72MP0002998_abnormal_bone_remodeling1.04143906
73MP0000383_abnormal_hair_follicle1.01466822
74MP0008057_abnormal_DNA_replication1.00648427
75MP0010678_abnormal_skin_adnexa1.00512352
76MP0002877_abnormal_melanocyte_morpholog0.99877528
77MP0005025_abnormal_response_to0.97867549
78MP0004381_abnormal_hair_follicle0.97794598
79MP0005058_abnormal_lysosome_morphology0.96235822
80MP0002168_other_aberrant_phenotype0.95668094
81MP0006082_CNS_inflammation0.95516580
82MP0000689_abnormal_spleen_morphology0.94843472
83MP0002722_abnormal_immune_system0.93292299
84MP0002148_abnormal_hypersensitivity_rea0.92888647
85MP0001958_emphysema0.92320254
86MP0002429_abnormal_blood_cell0.88012417
87MP0005164_abnormal_response_to0.87915689
88MP0003943_abnormal_hepatobiliary_system0.86715551
89MP0002933_joint_inflammation0.86323147
90MP0000516_abnormal_urinary_system0.85296745
91MP0005367_renal/urinary_system_phenotyp0.85296745
92MP0003453_abnormal_keratinocyte_physiol0.85235990
93MP0005670_abnormal_white_adipose0.83914857
94MP0002095_abnormal_skin_pigmentation0.83761959
95MP0002075_abnormal_coat/hair_pigmentati0.83597004
96MP0001915_intracranial_hemorrhage0.83349629
97MP0003448_altered_tumor_morphology0.82073631
98MP0004084_abnormal_cardiac_muscle0.81882486
99MP0008961_abnormal_basal_metabolism0.78484928
100MP0001845_abnormal_inflammatory_respons0.77764368
101MP0001243_abnormal_dermal_layer0.75491291
102MP0003221_abnormal_cardiomyocyte_apopto0.75047343
103MP0005379_endocrine/exocrine_gland_phen0.74975961
104MP0005023_abnormal_wound_healing0.74911555
105MP0001784_abnormal_fluid_regulation0.74751612
106MP0000627_abnormal_mammary_gland0.74691042
107MP0001853_heart_inflammation0.74681933
108MP0005257_abnormal_intraocular_pressure0.73658550
109MP0003828_pulmonary_edema0.73531557
110MP0002019_abnormal_tumor_incidence0.73424837
111MP0000470_abnormal_stomach_morphology0.73149895
112MP0003786_premature_aging0.72957116
113MP0002925_abnormal_cardiovascular_devel0.72890054
114MP0005666_abnormal_adipose_tissue0.72457542
115MP0004484_altered_response_of0.72063969
116MP0010368_abnormal_lymphatic_system0.71881729
117MP0008438_abnormal_cutaneous_collagen0.71010294
118MP0003279_aneurysm0.70674767
119MP0002060_abnormal_skin_morphology0.69319990
120MP0009785_altered_susceptibility_to0.68948719
121MP0003121_genomic_imprinting0.68467063
122MP0009384_cardiac_valve_regurgitation0.68391209
123MP0003890_abnormal_embryonic-extraembry0.68308485
124MP0005275_abnormal_skin_tensile0.67641382
125MP0000427_abnormal_hair_cycle0.66963922
126MP0003878_abnormal_ear_physiology0.66677404
127MP0005377_hearing/vestibular/ear_phenot0.66677404
128MP0001881_abnormal_mammary_gland0.66329478
129MP0002277_abnormal_respiratory_mucosa0.65684978
130MP0005621_abnormal_cell_physiology0.65543920
131MP0003984_embryonic_growth_retardation0.65465869
132MP0002088_abnormal_embryonic_growth/wei0.65324843
133MP0001533_abnormal_skeleton_physiology0.64902919
134MP0005375_adipose_tissue_phenotype0.64725944
135MP0003866_abnormal_defecation0.64507086
136MP0009333_abnormal_splenocyte_physiolog0.62849284
137MP0000249_abnormal_blood_vessel0.62721545
138MP0001191_abnormal_skin_condition0.62376220
139MP0002086_abnormal_extraembryonic_tissu0.60875304

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the fingertips (HP:0001211)5.07940098
2Peritonitis (HP:0002586)3.78206064
3Absent frontal sinuses (HP:0002688)3.48466170
4Elevated erythrocyte sedimentation rate (HP:0003565)3.42642144
5Tubulointerstitial nephritis (HP:0001970)3.30123849
6Abnormality of DNA repair (HP:0003254)3.22543291
7Recurrent viral infections (HP:0004429)3.02523123
8Progressive cerebellar ataxia (HP:0002073)3.02157447
9Macroorchidism (HP:0000053)3.00787355
10Recurrent fungal infections (HP:0002841)2.90180872
11Lip pit (HP:0100267)2.89722425
12Narrow palate (HP:0000189)2.86505920
13Volvulus (HP:0002580)2.82409945
14Sandal gap (HP:0001852)2.82124645
15Aortic aneurysm (HP:0004942)2.79828550
16Abnormality of the nasal septum (HP:0000419)2.77011580
17Urethral obstruction (HP:0000796)2.65701588
18Periodontitis (HP:0000704)2.61608879
19Gastrointestinal infarctions (HP:0005244)2.58863328
20Absent/shortened dynein arms (HP:0200106)2.57225842
21Dynein arm defect of respiratory motile cilia (HP:0012255)2.57225842
22Duplicated collecting system (HP:0000081)2.53512456
23Acute myeloid leukemia (HP:0004808)2.51411589
24Abnormality of T cells (HP:0002843)2.49135709
25Chronic hepatic failure (HP:0100626)2.44801945
26Autoimmune thrombocytopenia (HP:0001973)2.42780425
27Hematochezia (HP:0002573)2.40704786
28Hyperkalemia (HP:0002153)2.40307831
29Colitis (HP:0002583)2.38746531
30Long eyelashes (HP:0000527)2.38728068
31Abnormality of the peritoneum (HP:0002585)2.37571000
32Vasculitis (HP:0002633)2.35423101
33Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.33653564
34Spinal cord lesions (HP:0100561)2.33382700
35Syringomyelia (HP:0003396)2.33382700
36Abnormality of the renal collecting system (HP:0004742)2.33095794
37Chronic diarrhea (HP:0002028)2.32132394
38Autoimmune hemolytic anemia (HP:0001890)2.30126490
39Myocardial infarction (HP:0001658)2.29759250
40Menstrual irregularities (HP:0000858)2.29614345
41Osteolytic defects of the phalanges of the hand (HP:0009771)2.24293251
42Osteolytic defects of the hand bones (HP:0009699)2.24293251
43Cone-rod dystrophy (HP:0000548)2.23593150
44Chronic mucocutaneous candidiasis (HP:0002728)2.21543750
45Recurrent cutaneous fungal infections (HP:0011370)2.21543750
46Recurrent bacterial skin infections (HP:0005406)2.20846168
47Thyroiditis (HP:0100646)2.18296197
48Anal stenosis (HP:0002025)2.17792494
49Ectopic kidney (HP:0000086)2.16714028
50Chest pain (HP:0100749)2.15360268
51Cerebral aneurysm (HP:0004944)2.13570035
52Fatigue (HP:0012378)2.11450367
53Gingival bleeding (HP:0000225)2.11362905
54Enlarged epiphyses (HP:0010580)2.11012138
55Myositis (HP:0100614)2.09344811
56Inflammation of the large intestine (HP:0002037)2.08908413
57Granulocytopenia (HP:0001913)2.07008321
58Arterial thrombosis (HP:0004420)2.04593818
59Abnormality of the frontal sinuses (HP:0002687)2.04294986
60Spondylolisthesis (HP:0003302)2.03596030
61Low anterior hairline (HP:0000294)2.03192704
62Prolonged bleeding time (HP:0003010)2.00559336
63Abnormality of T cell number (HP:0011839)2.00402109
64Neoplasm of the tracheobronchial system (HP:0100552)2.00092820
65Stomach cancer (HP:0012126)1.99419765
66Panhypogammaglobulinemia (HP:0003139)1.98503383
67T lymphocytopenia (HP:0005403)1.98246933
68Acute hepatic failure (HP:0006554)1.96663251
69Depressed nasal tip (HP:0000437)1.96656494
70Slow saccadic eye movements (HP:0000514)1.96104811
71Recurrent abscess formation (HP:0002722)1.95464442
72Recurrent bronchitis (HP:0002837)1.94498852
73Orchitis (HP:0100796)1.93626392
74Eczematoid dermatitis (HP:0000976)1.93289502
75Limited elbow extension (HP:0001377)1.93015327
76Abnormal delayed hypersensitivity skin test (HP:0002963)1.92747352
77Heterotopia (HP:0002282)1.91724151
78Deep philtrum (HP:0002002)1.91718753
79Gingivitis (HP:0000230)1.90332304
80Hypoplastic ischia (HP:0003175)1.89981351
81Gastrointestinal inflammation (HP:0004386)1.88751554
82Agammaglobulinemia (HP:0004432)1.88481609
83Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.88299004
84Eosinophilia (HP:0001880)1.88174962
85Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.87844011
86Genetic anticipation (HP:0003743)1.87675468
87Acute lymphatic leukemia (HP:0006721)1.86884539
88Subacute progressive viral hepatitis (HP:0006572)1.86710111
89Hypoplasia of the thymus (HP:0000778)1.84463162
90Meningitis (HP:0001287)1.84260631
91Abnormality of T cell physiology (HP:0011840)1.83024716
92Distal lower limb amyotrophy (HP:0008944)1.82456025
93B lymphocytopenia (HP:0010976)1.81075432
94Abnormality of B cell number (HP:0010975)1.81075432
95Mitral valve prolapse (HP:0001634)1.80152449
96Stomatitis (HP:0010280)1.79662426
97Thyroid carcinoma (HP:0002890)1.79461793
98Recurrent pneumonia (HP:0006532)1.78808619
99Abnormality of incisor morphology (HP:0011063)1.78327284
100Abnormality of the hepatic vasculature (HP:0006707)1.78282806
101Portal hypertension (HP:0001409)1.77535022
102Abnormality of eosinophils (HP:0001879)1.76791219
103Overgrowth (HP:0001548)1.76115260
104Abnormality of macrophages (HP:0004311)1.75601251
105Mediastinal lymphadenopathy (HP:0100721)1.71994123
106Papillary thyroid carcinoma (HP:0002895)1.71638954
107Protruding tongue (HP:0010808)1.71230438
108Chromsome breakage (HP:0040012)1.71150599
109Pulmonary infiltrates (HP:0002113)1.70761099
110Dislocated radial head (HP:0003083)1.70142027
111Abnormality of pyrimidine metabolism (HP:0004353)1.69922373
112Recurrent skin infections (HP:0001581)1.69897751
113Thick nail (HP:0001805)1.69712376
114Neoplasm of the adrenal cortex (HP:0100641)1.69678788
115Abnormality of the ischium (HP:0003174)1.69615816
116Curly hair (HP:0002212)1.69202541
117Hemoptysis (HP:0002105)1.68943928
118Keratoconjunctivitis sicca (HP:0001097)1.68609138
119Clubbing of toes (HP:0100760)1.68487998
120Abnormality of chromosome stability (HP:0003220)1.68110738
121Lower limb amyotrophy (HP:0007210)1.67755404
122Prominent nose (HP:0000448)1.67528968
123Abnormality of the thoracic spine (HP:0100711)1.67275889
124Aplasia/Hypoplasia of the thymus (HP:0010515)1.66317427
125Aneurysm (HP:0002617)1.65866530
126Thick eyebrow (HP:0000574)1.65413971
127Pigmentary retinal degeneration (HP:0001146)1.62880574
128Short 4th metacarpal (HP:0010044)1.62434401
129Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.62434401
130Viral hepatitis (HP:0006562)1.61441308
131Chromosomal breakage induced by crosslinking agents (HP:0003221)1.60680118
132Tapered finger (HP:0001182)1.58941334
133Aqueductal stenosis (HP:0002410)1.58777186
134Hypochromic microcytic anemia (HP:0004840)1.58713070
135Increased IgE level (HP:0003212)1.58498596
136Abnormality of the radial head (HP:0003995)1.58108434
137Trigonocephaly (HP:0000243)1.57672298
138Esophageal varix (HP:0002040)1.57458256
139Submucous cleft hard palate (HP:0000176)1.55896201
140Smooth philtrum (HP:0000319)1.54405383
141Prostate neoplasm (HP:0100787)1.54114220
142Cutis marmorata (HP:0000965)1.54069322
143Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.53915300
144Persistence of primary teeth (HP:0006335)1.53457908
145Retrobulbar optic neuritis (HP:0100654)1.51981208
146Optic neuritis (HP:0100653)1.51981208
147Oligodontia (HP:0000677)1.51924374
148Disproportionate tall stature (HP:0001519)1.51729565
149Obsessive-compulsive behavior (HP:0000722)1.51457362
150Truncal obesity (HP:0001956)1.51452538
151Leukocytosis (HP:0001974)1.51062087

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.57702631
2MAP3K143.54169006
3PLK42.45221442
4JAK32.36718481
5CAMK1D2.28966662
6MAP3K132.23883345
7JAK12.15792642
8CAMK1G2.12990552
9TYK22.09150056
10NUAK12.02247683
11LATS12.00249957
12FGFR31.97718596
13TAOK31.93535202
14FRK1.91789035
15BRD41.87845907
16CHUK1.86483864
17PIK3CG1.80612653
18SIK21.80592866
19SGK31.73093545
20SIK11.66109410
21IKBKB1.62916526
22SGK21.58764073
23IKBKE1.54738180
24KIT1.46659150
25PTK61.45343179
26INSRR1.44785953
27RIPK11.44230946
28PRPF4B1.43185905
29RIPK41.41195773
30MAP4K11.39265145
31BLK1.38732953
32PRKAA21.35099492
33FGFR41.29972324
34MAP3K21.29581668
35BMPR21.27184470
36BRSK21.25370832
37TRPM71.25266536
38STK31.18718651
39CDK61.18642435
40EPHA31.16820850
41DMPK1.16141105
42MAP3K71.15180407
43MAP3K101.14121880
44ACVR1B1.11444279
45BMPR1B1.10838058
46TTN1.09974606
47TBK11.09819813
48WNK11.09816592
49FGFR21.07566541
50PDK11.07196219
51TXK1.06551110
52CSF1R1.04592036
53MTOR1.04057216
54TGFBR21.03559765
55STK381.01780240
56PDGFRB0.99808612
57EEF2K0.99387344
58NEK90.98827012
59HCK0.97510470
60IRAK40.96903126
61SGK10.95635357
62STK38L0.92580243
63ITK0.90010849
64TEC0.87868763
65EPHB10.82625976
66JAK20.82102822
67CDK90.81423976
68ERBB30.80022316
69KSR20.78618589
70NEK60.77291629
71MAP3K60.77234468
72TYRO30.73733220
73ZAK0.73002006
74RAF10.71704687
75LCK0.71616692
76NLK0.71463634
77CSK0.71298553
78PLK20.69524585
79MAP2K30.68943617
80ATR0.68042818
81ZAP700.67013710
82IRAK30.66922213
83MKNK20.65027567
84MELK0.64829202
85STK40.64096458
86PIM10.62562413
87SYK0.62098148
88PRKCQ0.61524875
89PKN20.61259891
90STK100.61125531
91IRAK10.60539470
92PDPK10.60369920
93RPS6KA40.60293838
94CDC42BPA0.59757315
95MARK20.59750094
96DAPK20.59655169
97FLT30.57164719
98SIK30.57094343
99PIK3CA0.57004129
100MAPK70.56019843
101SGK4940.55576172
102SGK2230.55576172
103DDR20.55333001
104LYN0.54507138
105PRKCH0.54496044
106RET0.54243158
107STK240.54188413
108PDGFRA0.52013651
109PTK20.51955002
110EGFR0.51461693
111PRKAA10.50416859
112CAMK40.50388070
113ATM0.50258172
114AKT10.49360296
115AKT30.49151020
116PNCK0.48532435
117MARK30.47940943
118HIPK20.47940717
119MAPK100.47435242
120BTK0.47397998
121ERBB20.46998014
122PKN10.46564271
123YES10.45402262
124MATK0.45046186
125RPS6KB20.44794847
126ABL10.44539319
127INSR0.44127893
128CDK30.42955538
129MAP3K10.42802076
130CDK40.42764926
131CHEK10.41985554
132MAPK10.41921906
133PTK2B0.41769805
134FES0.39320939
135MAPK110.39071902
136CAMKK20.36038972

Predicted pathways (KEGG)

RankGene SetZ-score
1NF-kappa B signaling pathway_Homo sapiens_hsa040642.23926133
2Lysine degradation_Homo sapiens_hsa003101.76020966
3Osteoclast differentiation_Homo sapiens_hsa043801.69754492
4Primary immunodeficiency_Homo sapiens_hsa053401.60015523
5NOD-like receptor signaling pathway_Homo sapiens_hsa046211.57507717
6B cell receptor signaling pathway_Homo sapiens_hsa046621.56564465
7Type I diabetes mellitus_Homo sapiens_hsa049401.52016813
8Measles_Homo sapiens_hsa051621.51604742
9Toll-like receptor signaling pathway_Homo sapiens_hsa046201.47726340
10Toxoplasmosis_Homo sapiens_hsa051451.45694445
11Leishmaniasis_Homo sapiens_hsa051401.45094075
12TNF signaling pathway_Homo sapiens_hsa046681.43978961
13Chronic myeloid leukemia_Homo sapiens_hsa052201.39715069
14Small cell lung cancer_Homo sapiens_hsa052221.38377217
15Phosphatidylinositol signaling system_Homo sapiens_hsa040701.33085176
16Fatty acid biosynthesis_Homo sapiens_hsa000611.30590896
17Asthma_Homo sapiens_hsa053101.29979292
18Intestinal immune network for IgA production_Homo sapiens_hsa046721.27004713
19RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.26583418
20T cell receptor signaling pathway_Homo sapiens_hsa046601.25321409
21Influenza A_Homo sapiens_hsa051641.24832053
22Jak-STAT signaling pathway_Homo sapiens_hsa046301.23454701
23Type II diabetes mellitus_Homo sapiens_hsa049301.21064839
24Transcriptional misregulation in cancer_Homo sapiens_hsa052021.19390390
25Acute myeloid leukemia_Homo sapiens_hsa052211.14759477
26Adherens junction_Homo sapiens_hsa045201.14562452
27Insulin resistance_Homo sapiens_hsa049311.13245716
28Chemokine signaling pathway_Homo sapiens_hsa040621.12949779
29MicroRNAs in cancer_Homo sapiens_hsa052061.12457977
30Hematopoietic cell lineage_Homo sapiens_hsa046401.11830022
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.11229362
32Herpes simplex infection_Homo sapiens_hsa051681.11170804
33Allograft rejection_Homo sapiens_hsa053301.10579383
34Pancreatic cancer_Homo sapiens_hsa052121.09639796
35Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.09096944
36Thyroid hormone signaling pathway_Homo sapiens_hsa049191.03929908
37VEGF signaling pathway_Homo sapiens_hsa043701.03911027
38AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.01658895
39Tuberculosis_Homo sapiens_hsa051521.01616401
40Inositol phosphate metabolism_Homo sapiens_hsa005621.01547551
41mTOR signaling pathway_Homo sapiens_hsa041500.98804898
42Hepatitis B_Homo sapiens_hsa051610.96988085
43Dorso-ventral axis formation_Homo sapiens_hsa043200.96646866
44Apoptosis_Homo sapiens_hsa042100.96413104
45Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.96372599
46Platelet activation_Homo sapiens_hsa046110.95679558
47Proteoglycans in cancer_Homo sapiens_hsa052050.95193584
48Hepatitis C_Homo sapiens_hsa051600.92323218
49Renal cell carcinoma_Homo sapiens_hsa052110.90904575
50Viral myocarditis_Homo sapiens_hsa054160.90120390
51Prostate cancer_Homo sapiens_hsa052150.89157949
52FoxO signaling pathway_Homo sapiens_hsa040680.88540961
53Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.88262673
54ABC transporters_Homo sapiens_hsa020100.87119260
55Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.86611700
56Leukocyte transendothelial migration_Homo sapiens_hsa046700.85650343
57Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.84178956
58Prolactin signaling pathway_Homo sapiens_hsa049170.83450729
59Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82993132
60Focal adhesion_Homo sapiens_hsa045100.81491013
61Carbohydrate digestion and absorption_Homo sapiens_hsa049730.81230915
62Neurotrophin signaling pathway_Homo sapiens_hsa047220.79899839
63Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79111693
64Non-small cell lung cancer_Homo sapiens_hsa052230.78288864
65Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.78218761
66Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.76588425
67Staphylococcus aureus infection_Homo sapiens_hsa051500.76300339
68Olfactory transduction_Homo sapiens_hsa047400.76250194
69Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.76110902
70Caffeine metabolism_Homo sapiens_hsa002320.75353169
71Endometrial cancer_Homo sapiens_hsa052130.75287537
72Legionellosis_Homo sapiens_hsa051340.74620400
73Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.74256056
74TGF-beta signaling pathway_Homo sapiens_hsa043500.74111245
75Longevity regulating pathway - mammal_Homo sapiens_hsa042110.73208938
76Sphingolipid signaling pathway_Homo sapiens_hsa040710.72526095
77Notch signaling pathway_Homo sapiens_hsa043300.72051625
78Amoebiasis_Homo sapiens_hsa051460.71919390
79Adipocytokine signaling pathway_Homo sapiens_hsa049200.71539674
80Graft-versus-host disease_Homo sapiens_hsa053320.70961172
81MAPK signaling pathway_Homo sapiens_hsa040100.70740531
82mRNA surveillance pathway_Homo sapiens_hsa030150.70705915
83Choline metabolism in cancer_Homo sapiens_hsa052310.69721009
84Long-term potentiation_Homo sapiens_hsa047200.69714941
85HTLV-I infection_Homo sapiens_hsa051660.69475222
86ECM-receptor interaction_Homo sapiens_hsa045120.68490095
87Glioma_Homo sapiens_hsa052140.66886765
88Antigen processing and presentation_Homo sapiens_hsa046120.66754488
89SNARE interactions in vesicular transport_Homo sapiens_hsa041300.65419472
90Malaria_Homo sapiens_hsa051440.64204785
91African trypanosomiasis_Homo sapiens_hsa051430.63940448
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.63503763
93Pathways in cancer_Homo sapiens_hsa052000.62846138
94GnRH signaling pathway_Homo sapiens_hsa049120.62413020
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.62132637
96Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.61743550
97Regulation of actin cytoskeleton_Homo sapiens_hsa048100.61123489
98Phospholipase D signaling pathway_Homo sapiens_hsa040720.60824784
99Colorectal cancer_Homo sapiens_hsa052100.59636604
100Renin secretion_Homo sapiens_hsa049240.59441504
101Glycerophospholipid metabolism_Homo sapiens_hsa005640.58360838
102ErbB signaling pathway_Homo sapiens_hsa040120.58011578
103Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57850879
104Autoimmune thyroid disease_Homo sapiens_hsa053200.57626816
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.57382866
106Estrogen signaling pathway_Homo sapiens_hsa049150.56639666
107Viral carcinogenesis_Homo sapiens_hsa052030.54339211
108Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.53950814
109Thyroid cancer_Homo sapiens_hsa052160.53587024
110Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.53479410
111Shigellosis_Homo sapiens_hsa051310.53393954
112Rap1 signaling pathway_Homo sapiens_hsa040150.53094703
113Salivary secretion_Homo sapiens_hsa049700.52993934
114Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.52769340
115cAMP signaling pathway_Homo sapiens_hsa040240.51812902
116Pertussis_Homo sapiens_hsa051330.51722044
117Phototransduction_Homo sapiens_hsa047440.50955121
118Circadian rhythm_Homo sapiens_hsa047100.50805966
119Long-term depression_Homo sapiens_hsa047300.50650692
120Non-homologous end-joining_Homo sapiens_hsa034500.49794168
121Aldosterone synthesis and secretion_Homo sapiens_hsa049250.49545760
122cGMP-PKG signaling pathway_Homo sapiens_hsa040220.49042152
123HIF-1 signaling pathway_Homo sapiens_hsa040660.48618105

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