ZFP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene belongs to the zinc finger protein family. Some members of this family bind to DNA by zinc-mediated secondary structures called zinc fingers, and are involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.94581614
2nucleobase catabolic process (GO:0046113)4.94382901
3cerebral cortex radially oriented cell migration (GO:0021799)4.47904997
4ribosomal small subunit biogenesis (GO:0042274)4.33378825
5gamma-aminobutyric acid transport (GO:0015812)4.31482675
6positive regulation of mitochondrial fission (GO:0090141)4.24413922
7termination of RNA polymerase III transcription (GO:0006386)4.22527472
8transcription elongation from RNA polymerase III promoter (GO:0006385)4.22527472
9maturation of SSU-rRNA (GO:0030490)4.01123937
10chaperone-mediated protein transport (GO:0072321)3.85351476
11mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.81722376
12presynaptic membrane assembly (GO:0097105)3.78633447
13DNA double-strand break processing (GO:0000729)3.76647653
14proteasome assembly (GO:0043248)3.75531586
15viral transcription (GO:0019083)3.74172479
16ATP synthesis coupled proton transport (GO:0015986)3.70475917
17energy coupled proton transport, down electrochemical gradient (GO:0015985)3.70475917
18ribosomal small subunit assembly (GO:0000028)3.70279282
19presynaptic membrane organization (GO:0097090)3.67511249
20regulation of development, heterochronic (GO:0040034)3.65763628
21forebrain neuron differentiation (GO:0021879)3.64369992
227-methylguanosine RNA capping (GO:0009452)3.61223666
23RNA capping (GO:0036260)3.61223666
247-methylguanosine mRNA capping (GO:0006370)3.60396420
25establishment of mitochondrion localization (GO:0051654)3.59473633
26translational termination (GO:0006415)3.58948353
27establishment of protein localization to mitochondrial membrane (GO:0090151)3.58112357
28cell migration in hindbrain (GO:0021535)3.56987973
29neuron recognition (GO:0008038)3.49030056
30limb bud formation (GO:0060174)3.49000918
31neural tube formation (GO:0001841)3.48477940
32transcription elongation from RNA polymerase I promoter (GO:0006362)3.47268352
33head development (GO:0060322)3.45835011
34DNA deamination (GO:0045006)3.42342593
35termination of RNA polymerase I transcription (GO:0006363)3.38933316
36mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.37172086
37mitochondrial respiratory chain complex I assembly (GO:0032981)3.37172086
38NADH dehydrogenase complex assembly (GO:0010257)3.37172086
39vocalization behavior (GO:0071625)3.34120380
40mannosylation (GO:0097502)3.30934986
41cotranslational protein targeting to membrane (GO:0006613)3.30298265
42mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.28243649
43central nervous system projection neuron axonogenesis (GO:0021952)3.27978560
44protein complex biogenesis (GO:0070271)3.26278080
45GTP biosynthetic process (GO:0006183)3.25759522
46rRNA modification (GO:0000154)3.24920493
47establishment of integrated proviral latency (GO:0075713)3.24846822
48L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.24779244
49protein localization to cilium (GO:0061512)3.24571160
50regulation of timing of cell differentiation (GO:0048505)3.23840708
51SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.22681881
52glycosphingolipid biosynthetic process (GO:0006688)3.20317658
53protein neddylation (GO:0045116)3.19934925
54protein targeting to ER (GO:0045047)3.19562865
55preassembly of GPI anchor in ER membrane (GO:0016254)3.16036287
56rRNA methylation (GO:0031167)3.14662766
57neuron cell-cell adhesion (GO:0007158)3.13611829
58axonal fasciculation (GO:0007413)3.12712403
59somite development (GO:0061053)3.12137958
60hippocampus development (GO:0021766)3.08407958
61olfactory bulb development (GO:0021772)3.07726326
62ribosomal large subunit biogenesis (GO:0042273)3.07545947
63transmission of nerve impulse (GO:0019226)3.05943299
64protein localization to endoplasmic reticulum (GO:0070972)3.05570611
65establishment of protein localization to endoplasmic reticulum (GO:0072599)3.05046329
66neurotransmitter-gated ion channel clustering (GO:0072578)3.05008831
67axon ensheathment in central nervous system (GO:0032291)3.04903467
68central nervous system myelination (GO:0022010)3.04903467
69glial cell proliferation (GO:0014009)3.03393274
70viral protein processing (GO:0019082)3.01444989
71mitochondrial respiratory chain complex assembly (GO:0033108)3.01037396
72cerebral cortex cell migration (GO:0021795)3.01036297
73transcription from RNA polymerase I promoter (GO:0006360)3.00594350
74central nervous system neuron axonogenesis (GO:0021955)2.96990221
75viral life cycle (GO:0019058)2.96802796
76respiratory chain complex IV assembly (GO:0008535)2.96249529
77GPI anchor biosynthetic process (GO:0006506)2.95819744
78establishment of viral latency (GO:0019043)2.94912791
79dendrite morphogenesis (GO:0048813)2.94644206
80cellular protein complex disassembly (GO:0043624)2.89138935
81cilium morphogenesis (GO:0060271)2.88493953
82cullin deneddylation (GO:0010388)2.88274012
83DNA damage response, detection of DNA damage (GO:0042769)2.88010915
84retinal ganglion cell axon guidance (GO:0031290)2.85766277
85maturation of 5.8S rRNA (GO:0000460)2.85381782
86translational elongation (GO:0006414)2.85259003
87ribonucleoprotein complex biogenesis (GO:0022613)2.84978637
88transcription initiation from RNA polymerase I promoter (GO:0006361)2.82270935
89regulation of feeding behavior (GO:0060259)2.82241661
90negative regulation of synaptic transmission, GABAergic (GO:0032229)2.81037187
91nonmotile primary cilium assembly (GO:0035058)2.80935519
92synapse assembly (GO:0007416)2.79838422
93regulation of telomere maintenance (GO:0032204)2.79768848
94cellular component biogenesis (GO:0044085)2.79333865
95C4-dicarboxylate transport (GO:0015740)2.79258891
96transcription-coupled nucleotide-excision repair (GO:0006283)2.78571505
97peptidyl-histidine modification (GO:0018202)2.77866404
98postsynaptic membrane organization (GO:0001941)2.76732182
99synaptic vesicle maturation (GO:0016188)2.76705714
100guanosine-containing compound biosynthetic process (GO:1901070)2.73956584
101nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.72887943
102UTP biosynthetic process (GO:0006228)2.72744195
103rRNA processing (GO:0006364)2.72055804
104sympathetic nervous system development (GO:0048485)2.71727928
105intraciliary transport (GO:0042073)2.70232025
106negative regulation of neurotransmitter transport (GO:0051589)2.69388452
107ionotropic glutamate receptor signaling pathway (GO:0035235)2.69047117
108translational initiation (GO:0006413)2.68432969
109viral mRNA export from host cell nucleus (GO:0046784)2.68089271
110nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.67958997
111intra-S DNA damage checkpoint (GO:0031573)2.67162491
112negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.66831707
113layer formation in cerebral cortex (GO:0021819)2.66220702
114translation (GO:0006412)2.65991948
115epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.65186998
116hindbrain development (GO:0030902)2.64223187
117DNA-templated transcription, elongation (GO:0006354)2.63592077
118microtubule depolymerization (GO:0007019)2.62199825
119negative regulation of dendrite development (GO:2000171)2.61846062
120calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.61790457
121rRNA metabolic process (GO:0016072)2.60998566
122transcription elongation from RNA polymerase II promoter (GO:0006368)2.60130951
123spliceosomal snRNP assembly (GO:0000387)2.59624278
124regulation of mitochondrial fission (GO:0090140)2.59449206
125DNA integration (GO:0015074)2.58619316
126tRNA modification (GO:0006400)2.58102692
127exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.57908660
128DNA ligation (GO:0006266)2.57717413
129G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.56983000
130regulation of growth hormone secretion (GO:0060123)2.56693221
131transcription from RNA polymerase III promoter (GO:0006383)2.56251729
132cholesterol biosynthetic process (GO:0006695)2.55703275
133GPI anchor metabolic process (GO:0006505)2.55526697
134pseudouridine synthesis (GO:0001522)2.54601650
135positive regulation of dendritic spine morphogenesis (GO:0061003)2.54030647
136negative regulation of oligodendrocyte differentiation (GO:0048715)2.53916800
137DNA-templated transcription, termination (GO:0006353)2.53765802
138protein K11-linked deubiquitination (GO:0035871)2.53674480
139regulation of telomere maintenance via telomerase (GO:0032210)2.53436459
140respiratory electron transport chain (GO:0022904)2.52987599
141sequestering of actin monomers (GO:0042989)2.52338470
142RNA methylation (GO:0001510)2.51071522
143protein complex disassembly (GO:0043241)2.50573706
144positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.49971167
145positive regulation of amino acid transport (GO:0051957)2.49085271
146protein deneddylation (GO:0000338)2.48860239
147electron transport chain (GO:0022900)2.47716793
148cerebral cortex neuron differentiation (GO:0021895)2.45697650
149negative regulation of DNA recombination (GO:0045910)2.45484524
150tRNA processing (GO:0008033)2.45068259
151tRNA methylation (GO:0030488)2.43364218
152positive regulation of viral transcription (GO:0050434)2.43271603
153glutamate receptor signaling pathway (GO:0007215)2.43176773
154macromolecular complex disassembly (GO:0032984)2.43167795
155microtubule polymerization or depolymerization (GO:0031109)2.42623932
156glutamate secretion (GO:0014047)2.41919205
157negative regulation of transcription by competitive promoter binding (GO:0010944)2.41867088
158cytochrome complex assembly (GO:0017004)2.41822523
159ephrin receptor signaling pathway (GO:0048013)2.41811055
160protein localization to synapse (GO:0035418)2.41688159
161regulation of helicase activity (GO:0051095)2.41635995
162protein targeting to mitochondrion (GO:0006626)2.41338227
163limb development (GO:0060173)2.41302476
164appendage development (GO:0048736)2.41302476
165regulation of dendritic spine morphogenesis (GO:0061001)2.40416948
166negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.40305919
167mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.39139916
168positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.39139916
169neurotransmitter secretion (GO:0007269)2.38249166
170spliceosomal complex assembly (GO:0000245)2.38064143
171regulation of DNA endoreduplication (GO:0032875)2.38044931
172neuronal stem cell maintenance (GO:0097150)2.37848031
173dopamine transport (GO:0015872)2.37083049
174neuron migration (GO:0001764)2.36851180
175mechanosensory behavior (GO:0007638)2.36355597
176cilium assembly (GO:0042384)2.36308114
177mitochondrion transport along microtubule (GO:0047497)2.36092531
178establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.36092531
179mitochondrial fission (GO:0000266)2.33915540
180synaptic transmission, glutamatergic (GO:0035249)2.33606685
181neuronal action potential propagation (GO:0019227)2.33407550
182response to pheromone (GO:0019236)2.31923687
183positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.31515369
184cilium organization (GO:0044782)2.31325244
185regulation of cilium movement (GO:0003352)2.30009365
186auditory behavior (GO:0031223)2.29989252
187regulation of synaptic vesicle exocytosis (GO:2000300)2.29862226
188negative regulation of telomere maintenance (GO:0032205)2.29086079
189inner ear receptor stereocilium organization (GO:0060122)2.28577140
190neuron fate commitment (GO:0048663)2.28348446
191isoprenoid biosynthetic process (GO:0008299)2.27826882
192negative regulation of axon extension (GO:0030517)2.27552842

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.62022701
2EZH2_22144423_ChIP-Seq_EOC_Human3.47332344
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.45536750
4HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.18161510
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.16371504
6ZNF274_21170338_ChIP-Seq_K562_Hela3.15885237
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.11904103
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.83550740
9* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.76113243
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.71926139
11NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.67314885
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.54023591
13* ETS1_20019798_ChIP-Seq_JURKAT_Human2.52479936
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.49657431
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.46709897
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.45173583
17GBX2_23144817_ChIP-Seq_PC3_Human2.43965005
18ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.33696845
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.29313840
20TAF15_26573619_Chip-Seq_HEK293_Human2.22175020
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.05087067
22ZFP57_27257070_Chip-Seq_ESCs_Mouse1.99509615
23VDR_23849224_ChIP-Seq_CD4+_Human1.98764320
24SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.91494293
25FUS_26573619_Chip-Seq_HEK293_Human1.90426861
26* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.87230196
27PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.83940904
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.79408443
29POU5F1_16153702_ChIP-ChIP_HESCs_Human1.78699821
30VDR_22108803_ChIP-Seq_LS180_Human1.78409978
31* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.74202919
32OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.74138484
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.73001408
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.72389610
35* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.72386314
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.71782038
37* FOXP3_21729870_ChIP-Seq_TREG_Human1.68515485
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.68427137
39BMI1_23680149_ChIP-Seq_NPCS_Mouse1.67870943
40CREB1_15753290_ChIP-ChIP_HEK293T_Human1.67177774
41SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.67016554
42YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.66832481
43AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.64237840
44ELK1_19687146_ChIP-ChIP_HELA_Human1.61912590
45* SRF_21415370_ChIP-Seq_HL-1_Mouse1.59537242
46SMAD4_21799915_ChIP-Seq_A2780_Human1.59479390
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58392964
48PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56416325
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56081794
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.51498305
51CBP_20019798_ChIP-Seq_JUKART_Human1.51197391
52IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.51197391
53POU3F2_20337985_ChIP-ChIP_501MEL_Human1.50118956
54EWS_26573619_Chip-Seq_HEK293_Human1.49662435
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.49516152
56PCGF2_27294783_Chip-Seq_ESCs_Mouse1.49074076
57IRF1_19129219_ChIP-ChIP_H3396_Human1.48306445
58AR_21572438_ChIP-Seq_LNCaP_Human1.47691822
59MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.47682789
60UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.42877082
61ER_23166858_ChIP-Seq_MCF-7_Human1.41307136
62* TTF2_22483619_ChIP-Seq_HELA_Human1.41279755
63E2F4_17652178_ChIP-ChIP_JURKAT_Human1.39924000
64DCP1A_22483619_ChIP-Seq_HELA_Human1.39319602
65RNF2_27304074_Chip-Seq_NSC_Mouse1.39310427
66AR_25329375_ChIP-Seq_VCAP_Human1.38655437
67TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38114397
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.37901097
69STAT3_23295773_ChIP-Seq_U87_Human1.36965082
70PADI4_21655091_ChIP-ChIP_MCF-7_Human1.36763268
71MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36268347
72* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.35590363
73NOTCH1_21737748_ChIP-Seq_TLL_Human1.35280679
74GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.34894260
75PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.34607942
76MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.34186281
77CBX2_27304074_Chip-Seq_ESCs_Mouse1.31443666
78SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.31270169
79CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26502871
80* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.24889234
81TP63_19390658_ChIP-ChIP_HaCaT_Human1.23409904
82BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.22338995
83XRN2_22483619_ChIP-Seq_HELA_Human1.22247437
84RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.21738148
85SOX9_26525672_Chip-Seq_HEART_Mouse1.20724544
86E2F1_18555785_ChIP-Seq_MESCs_Mouse1.19955251
87POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.19505871
88REST_18959480_ChIP-ChIP_MESCs_Mouse1.19272303
89GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17640427
90P300_19829295_ChIP-Seq_ESCs_Human1.17418015
91IGF1R_20145208_ChIP-Seq_DFB_Human1.16844917
92MYC_18940864_ChIP-ChIP_HL60_Human1.16764573
93POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.16384554
94TCF4_23295773_ChIP-Seq_U87_Human1.16125069
95CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16104842
96NR3C1_21868756_ChIP-Seq_MCF10A_Human1.14521478
97KLF5_20875108_ChIP-Seq_MESCs_Mouse1.14467819
98JARID2_20064375_ChIP-Seq_MESCs_Mouse1.13951738
99SOX2_21211035_ChIP-Seq_LN229_Gbm1.13037874
100TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12113458
101ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.11769810
102KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.11356073
103* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.09733352
104RUNX2_22187159_ChIP-Seq_PCA_Human1.09158932
105NANOG_18555785_Chip-Seq_ESCs_Mouse1.07863956
106POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07688312
107TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07688312
108E2F7_22180533_ChIP-Seq_HELA_Human1.06105904
109CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02716048
110SOX2_16153702_ChIP-ChIP_HESCs_Human1.02423431
111RBPJ_22232070_ChIP-Seq_NCS_Mouse1.01374494
112EZH2_27304074_Chip-Seq_ESCs_Mouse1.01067345
113FLI1_21867929_ChIP-Seq_TH2_Mouse1.00008710
114NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.99907672
115STAT3_18555785_Chip-Seq_ESCs_Mouse0.99432692
116SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.98582389
117TCF4_22108803_ChIP-Seq_LS180_Human0.98208551
118BCAT_22108803_ChIP-Seq_LS180_Human0.97814812
119P300_18555785_Chip-Seq_ESCs_Mouse0.97328233
120JUN_21703547_ChIP-Seq_K562_Human0.97241969
121WT1_19549856_ChIP-ChIP_CCG9911_Human0.97216701
122LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97189341
123SUZ12_18555785_Chip-Seq_ESCs_Mouse0.96528969
124EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.96137667
125E2F1_18555785_Chip-Seq_ESCs_Mouse0.94698792
126SUZ12_27294783_Chip-Seq_NPCs_Mouse0.94023131
127MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.93523048
128REST_21632747_ChIP-Seq_MESCs_Mouse0.93363578
129SMAD_19615063_ChIP-ChIP_OVARY_Human0.92966991
130CIITA_25753668_ChIP-Seq_RAJI_Human0.92024942
131P53_22387025_ChIP-Seq_ESCs_Mouse0.91438870
132FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.91267727
133TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.91184650
134TAL1_26923725_Chip-Seq_HPCs_Mouse0.91138850
135GABP_19822575_ChIP-Seq_HepG2_Human0.90548753
136ELK1_22589737_ChIP-Seq_MCF10A_Human0.90174444
137NFE2_27457419_Chip-Seq_LIVER_Mouse0.89555317
138EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.88578811
139LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.88134318
140SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.86691143
141SOX2_18555785_ChIP-Seq_MESCs_Mouse0.86533319
142SALL1_21062744_ChIP-ChIP_HESCs_Human0.86014881
143NMYC_18555785_Chip-Seq_ESCs_Mouse0.86004736
144CMYC_18555785_Chip-Seq_ESCs_Mouse0.85956057
145RUNX1_27457419_Chip-Seq_LIVER_Mouse0.85302068
146MYCN_18555785_ChIP-Seq_MESCs_Mouse0.84828720
147NELFA_20434984_ChIP-Seq_ESCs_Mouse0.83623283
148CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.81785460

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.12430051
2MP0001188_hyperpigmentation3.35133463
3MP0003136_yellow_coat_color3.22988789
4MP0006292_abnormal_olfactory_placode3.02973967
5MP0005394_taste/olfaction_phenotype2.63156404
6MP0005499_abnormal_olfactory_system2.63156404
7MP0001529_abnormal_vocalization2.51290781
8MP0009379_abnormal_foot_pigmentation2.51059971
9MP0008057_abnormal_DNA_replication2.41568602
10MP0002234_abnormal_pharynx_morphology2.32792161
11MP0005171_absent_coat_pigmentation2.30401623
12MP0002638_abnormal_pupillary_reflex2.24525884
13MP0008058_abnormal_DNA_repair2.15636583
14MP0005409_darkened_coat_color2.03037174
15MP0002102_abnormal_ear_morphology2.00751285
16MP0001905_abnormal_dopamine_level1.93600731
17MP0002163_abnormal_gland_morphology1.93299767
18MP0004142_abnormal_muscle_tone1.93118659
19MP0005423_abnormal_somatic_nervous1.92397673
20MP0001968_abnormal_touch/_nociception1.83606437
21MP0002272_abnormal_nervous_system1.82280425
22MP0001986_abnormal_taste_sensitivity1.77141588
23MP0008877_abnormal_DNA_methylation1.73216766
24MP0009745_abnormal_behavioral_response1.68503468
25MP0002064_seizures1.66047895
26MP0004381_abnormal_hair_follicle1.65306225
27MP0002572_abnormal_emotion/affect_behav1.65197809
28MP0006276_abnormal_autonomic_nervous1.63863304
29MP0005075_abnormal_melanosome_morpholog1.63349262
30MP0003635_abnormal_synaptic_transmissio1.60745440
31MP0002233_abnormal_nose_morphology1.60455443
32MP0001486_abnormal_startle_reflex1.58567082
33MP0002736_abnormal_nociception_after1.57946428
34MP0002653_abnormal_ependyma_morphology1.56277870
35MP0005379_endocrine/exocrine_gland_phen1.50723425
36MP0005187_abnormal_penis_morphology1.49029799
37MP0004811_abnormal_neuron_physiology1.47165822
38MP0010094_abnormal_chromosome_stability1.47128410
39MP0000015_abnormal_ear_pigmentation1.44763400
40MP0002735_abnormal_chemical_nociception1.43116080
41MP0005174_abnormal_tail_pigmentation1.41380537
42MP0005646_abnormal_pituitary_gland1.41311617
43MP0003786_premature_aging1.39286915
44MP0006072_abnormal_retinal_apoptosis1.34370529
45MP0002938_white_spotting1.33992087
46MP0002063_abnormal_learning/memory/cond1.32649938
47MP0004859_abnormal_synaptic_plasticity1.30118044
48MP0000566_synostosis1.29232457
49MP0002928_abnormal_bile_duct1.29177666
50MP0002067_abnormal_sensory_capabilities1.28857400
51MP0004134_abnormal_chest_morphology1.28185414
52MP0001485_abnormal_pinna_reflex1.27832380
53MP0001984_abnormal_olfaction1.27332426
54MP0003937_abnormal_limbs/digits/tail_de1.27329023
55MP0009046_muscle_twitch1.26846834
56MP0008995_early_reproductive_senescence1.26055592
57MP0005645_abnormal_hypothalamus_physiol1.25805832
58MP0002095_abnormal_skin_pigmentation1.24764713
59MP0003890_abnormal_embryonic-extraembry1.23858637
60MP0001963_abnormal_hearing_physiology1.23684374
61MP0001177_atelectasis1.22313752
62MP0000778_abnormal_nervous_system1.22211059
63MP0004957_abnormal_blastocyst_morpholog1.21557098
64MP0003861_abnormal_nervous_system1.21444595
65MP0004270_analgesia1.19797354
66MP0003755_abnormal_palate_morphology1.19738720
67MP0003941_abnormal_skin_development1.17801403
68MP0001299_abnormal_eye_distance/1.17313903
69MP0002184_abnormal_innervation1.15849765
70MP0000372_irregular_coat_pigmentation1.13961371
71MP0000569_abnormal_digit_pigmentation1.13124478
72MP0003938_abnormal_ear_development1.12781379
73MP0002152_abnormal_brain_morphology1.12568720
74MP0000647_abnormal_sebaceous_gland1.12540382
75MP0000631_abnormal_neuroendocrine_gland1.11856740
76MP0003385_abnormal_body_wall1.11711647
77MP0004742_abnormal_vestibular_system1.09707500
78MP0005551_abnormal_eye_electrophysiolog1.08624214
79MP0008932_abnormal_embryonic_tissue1.08513851
80MP0001293_anophthalmia1.07680848
81MP0002822_catalepsy1.06262395
82MP0003315_abnormal_perineum_morphology1.06146493
83MP0003122_maternal_imprinting1.05683852
84MP0003221_abnormal_cardiomyocyte_apopto1.04922986
85MP0003119_abnormal_digestive_system1.04547305
86MP0002837_dystrophic_cardiac_calcinosis1.02562146
87MP0005248_abnormal_Harderian_gland1.01894621
88MP0002734_abnormal_mechanical_nocicepti1.01561744
89MP0000026_abnormal_inner_ear1.01120305
90MP0003693_abnormal_embryo_hatching1.00942760
91MP0001970_abnormal_pain_threshold1.00398274
92MP0001286_abnormal_eye_development0.99352095
93MP0005253_abnormal_eye_physiology0.99036671
94MP0008569_lethality_at_weaning0.98589871
95MP0001440_abnormal_grooming_behavior0.98108058
96MP0002752_abnormal_somatic_nervous0.96506206
97MP0001502_abnormal_circadian_rhythm0.96125866
98MP0002557_abnormal_social/conspecific_i0.94702380
99MP0000049_abnormal_middle_ear0.93985527
100MP0000920_abnormal_myelination0.93889415
101MP0004133_heterotaxia0.93861522
102MP0003111_abnormal_nucleus_morphology0.93155699
103MP0002876_abnormal_thyroid_physiology0.92843254
104MP0002751_abnormal_autonomic_nervous0.92041779
105MP0002396_abnormal_hematopoietic_system0.91772391
106MP0003763_abnormal_thymus_physiology0.90469606
107MP0003077_abnormal_cell_cycle0.89579070
108MP0003935_abnormal_craniofacial_develop0.89146721
109MP0004197_abnormal_fetal_growth/weight/0.86559641
110MP0009703_decreased_birth_body0.85936505
111MP0002081_perinatal_lethality0.84923486
112MP0000516_abnormal_urinary_system0.84914819
113MP0005367_renal/urinary_system_phenotyp0.84914819
114MP0005391_vision/eye_phenotype0.84016310
115MP0002882_abnormal_neuron_morphology0.83327271
116MP0002132_abnormal_respiratory_system0.83231700
117MP0002733_abnormal_thermal_nociception0.83032561
118MP0002009_preneoplasia0.81980458
119MP0004145_abnormal_muscle_electrophysio0.81075258
120MP0001501_abnormal_sleep_pattern0.80462240
121MP0003121_genomic_imprinting0.79704374
122MP0005195_abnormal_posterior_eye0.79444508
123MP0002177_abnormal_outer_ear0.79370173
124MP0000955_abnormal_spinal_cord0.77701151
125MP0009697_abnormal_copulation0.77433702
126MP0002210_abnormal_sex_determination0.76809591
127MP0000534_abnormal_ureter_morphology0.75485979
128MP0008007_abnormal_cellular_replicative0.73756899
129MP0003787_abnormal_imprinting0.73744214
130MP0005671_abnormal_response_to0.73688339
131MP0003567_abnormal_fetal_cardiomyocyte0.73277676
132MP0003698_abnormal_male_reproductive0.72911942
133MP0002066_abnormal_motor_capabilities/c0.72270542
134MP0002249_abnormal_larynx_morphology0.70901867
135MP0001943_abnormal_respiration0.70288103
136MP0004924_abnormal_behavior0.69783756
137MP0005386_behavior/neurological_phenoty0.69783756
138MP0002069_abnormal_eating/drinking_beha0.69579600
139MP0008789_abnormal_olfactory_epithelium0.68638647
140MP0002229_neurodegeneration0.67981257

Predicted human phenotypes

RankGene SetZ-score
1Drooling (HP:0002307)3.53766354
2Acute necrotizing encephalopathy (HP:0006965)3.43744044
3Excessive salivation (HP:0003781)3.21886238
4Focal motor seizures (HP:0011153)3.13393530
5Mitochondrial inheritance (HP:0001427)3.04610905
6Reticulocytopenia (HP:0001896)3.03590175
73-Methylglutaconic aciduria (HP:0003535)3.03521205
8Nephrogenic diabetes insipidus (HP:0009806)2.95942014
9Hepatoblastoma (HP:0002884)2.95563194
10Abnormality of cells of the erythroid lineage (HP:0012130)2.90992335
11Cortical dysplasia (HP:0002539)2.88192181
12Abnormal mitochondria in muscle tissue (HP:0008316)2.87179786
13Medial flaring of the eyebrow (HP:0010747)2.81786690
14Progressive macrocephaly (HP:0004481)2.78845203
15Progressive inability to walk (HP:0002505)2.75016447
16Absent speech (HP:0001344)2.73344770
17Gait imbalance (HP:0002141)2.71208790
18Lissencephaly (HP:0001339)2.68040798
19Chronic hepatic failure (HP:0100626)2.65352123
20Congenital primary aphakia (HP:0007707)2.64817668
21Urinary urgency (HP:0000012)2.64150954
22Duplicated collecting system (HP:0000081)2.63873010
23Abnormality of midbrain morphology (HP:0002418)2.61955140
24Molar tooth sign on MRI (HP:0002419)2.61955140
25Abnormality of the renal collecting system (HP:0004742)2.61739594
26Abnormal number of erythroid precursors (HP:0012131)2.58744415
27Increased CSF lactate (HP:0002490)2.54058405
28Split foot (HP:0001839)2.53496003
29Abnormal respiratory motile cilium morphology (HP:0005938)2.51799680
30Abnormal respiratory epithelium morphology (HP:0012253)2.51799680
31Tubulointerstitial nephritis (HP:0001970)2.49472674
32Increased hepatocellular lipid droplets (HP:0006565)2.49129732
33Abnormal hair whorl (HP:0010721)2.45364632
34Cerebral hypomyelination (HP:0006808)2.45156335
35Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.43129571
36Medulloblastoma (HP:0002885)2.39542044
37True hermaphroditism (HP:0010459)2.38882955
38Pachygyria (HP:0001302)2.37425492
39Pancreatic fibrosis (HP:0100732)2.37137941
40Oligodactyly (hands) (HP:0001180)2.36428063
41Hepatocellular necrosis (HP:0001404)2.35719387
42Acute encephalopathy (HP:0006846)2.35295233
43Vaginal atresia (HP:0000148)2.34874492
44Aplasia/Hypoplasia of the tongue (HP:0010295)2.34451810
45Renal Fanconi syndrome (HP:0001994)2.33564271
46Astrocytoma (HP:0009592)2.33208164
47Abnormality of the astrocytes (HP:0100707)2.33208164
48Type I transferrin isoform profile (HP:0003642)2.30309788
49Genital tract atresia (HP:0001827)2.29335681
50Specific learning disability (HP:0001328)2.27795726
51Birth length less than 3rd percentile (HP:0003561)2.27147418
52Pancreatic cysts (HP:0001737)2.24548019
53Chromosomal breakage induced by crosslinking agents (HP:0003221)2.22283819
54Retinal dysplasia (HP:0007973)2.21287455
55Abnormality of DNA repair (HP:0003254)2.20887161
56Chromsome breakage (HP:0040012)2.20769044
57Volvulus (HP:0002580)2.19618118
58Postaxial foot polydactyly (HP:0001830)2.19377098
59Broad-based gait (HP:0002136)2.18870740
60Postaxial hand polydactyly (HP:0001162)2.17484717
61Colon cancer (HP:0003003)2.15053950
62Papillary thyroid carcinoma (HP:0002895)2.15034867
63Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.14480108
64Inability to walk (HP:0002540)2.14081262
65Intestinal atresia (HP:0011100)2.14042783
66Hypothermia (HP:0002045)2.12856293
67Supernumerary spleens (HP:0009799)2.11747372
68Abnormality of the axillary hair (HP:0100134)2.10485528
69Abnormality of secondary sexual hair (HP:0009888)2.10485528
70Duplication of thumb phalanx (HP:0009942)2.10284589
71Renal cortical cysts (HP:0000803)2.10135993
72Neoplasm of the oral cavity (HP:0100649)2.08980182
73Hypsarrhythmia (HP:0002521)2.08030191
74Focal seizures (HP:0007359)2.07826631
75Abnormal ciliary motility (HP:0012262)2.07547213
76Glioma (HP:0009733)2.06647498
77Nephronophthisis (HP:0000090)2.04826991
78Tented upper lip vermilion (HP:0010804)2.04816322
79Peripheral hypomyelination (HP:0007182)2.04466189
80Renal hypoplasia (HP:0000089)2.03901317
81Optic disc pallor (HP:0000543)2.03684083
82Large earlobe (HP:0009748)2.02091405
83Microvesicular hepatic steatosis (HP:0001414)2.01047549
84Abnormality of the metopic suture (HP:0005556)2.00555012
85Poor coordination (HP:0002370)2.00189630
86Macrocytic anemia (HP:0001972)1.99931901
87Irregular epiphyses (HP:0010582)1.98680203
88Hyperglycinemia (HP:0002154)1.97596272
89Hemiparesis (HP:0001269)1.96837006
90Intellectual disability, moderate (HP:0002342)1.96396170
91Anencephaly (HP:0002323)1.96028227
92Ependymoma (HP:0002888)1.95833796
93EEG with generalized epileptiform discharges (HP:0011198)1.95830810
94Thyroid-stimulating hormone excess (HP:0002925)1.95501546
95Respiratory difficulties (HP:0002880)1.95347391
96Abnormality of the columella (HP:0009929)1.94169122
97Epileptic encephalopathy (HP:0200134)1.94125938
98Narrow forehead (HP:0000341)1.93663901
99Atonic seizures (HP:0010819)1.92979731
100Leukodystrophy (HP:0002415)1.92105243
101Micropenis (HP:0000054)1.91580638
102Bifid tongue (HP:0010297)1.90804242
103Decreased testicular size (HP:0008734)1.90688604
104Absent thumb (HP:0009777)1.90682991
105Epileptiform EEG discharges (HP:0011182)1.90227523
106Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.89930806
107Occipital encephalocele (HP:0002085)1.89279266
108Broad foot (HP:0001769)1.89170934
109Febrile seizures (HP:0002373)1.88958466
110Cystic liver disease (HP:0006706)1.88609687
111Exotropia (HP:0000577)1.88533955
112Amyotrophic lateral sclerosis (HP:0007354)1.87352425
113Hyperventilation (HP:0002883)1.84959136
114Aplasia/hypoplasia of the uterus (HP:0008684)1.84168882
115Polyphagia (HP:0002591)1.82583093
116Facial hemangioma (HP:0000329)1.82114881
117Increased serum lactate (HP:0002151)1.81618863
118Aplastic anemia (HP:0001915)1.81211074
119Patchy hypopigmentation of hair (HP:0011365)1.81134043
120Postnatal microcephaly (HP:0005484)1.80978077
121Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.80968756
122Pallor (HP:0000980)1.80822641
123Hypoplasia of the corpus callosum (HP:0002079)1.80255368
124Preaxial hand polydactyly (HP:0001177)1.79530203
125Gastrointestinal atresia (HP:0002589)1.79176225
126Abnormality of the preputium (HP:0100587)1.78818005
127Abnormality of the labia minora (HP:0012880)1.78682393
128Oligodactyly (HP:0012165)1.77646431
129Progressive cerebellar ataxia (HP:0002073)1.77231323
130Sclerocornea (HP:0000647)1.76528586
131Abnormality of the septum pellucidum (HP:0007375)1.76123535
132Protruding tongue (HP:0010808)1.75336868
133Abnormal lung lobation (HP:0002101)1.74866142
134Hemivertebrae (HP:0002937)1.74705363
135Optic nerve hypoplasia (HP:0000609)1.73988050
136Dyskinesia (HP:0100660)1.73935867
137Median cleft lip (HP:0000161)1.73662468
138Thyroid carcinoma (HP:0002890)1.73551956
139Exercise intolerance (HP:0003546)1.73271268
140Exertional dyspnea (HP:0002875)1.72922124
141Spastic tetraplegia (HP:0002510)1.72107724
142Absent septum pellucidum (HP:0001331)1.72100728
143Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.71391884
144Decreased activity of mitochondrial respiratory chain (HP:0008972)1.71391884
145Increased serum pyruvate (HP:0003542)1.71365446
146Partial duplication of thumb phalanx (HP:0009944)1.71302659
147Rhinitis (HP:0012384)1.71222588
148Abnormality of the renal medulla (HP:0100957)1.70779582
149Septo-optic dysplasia (HP:0100842)1.70025296
150Aganglionic megacolon (HP:0002251)1.69808729
151Hypoplasia of the brainstem (HP:0002365)1.69414099
152Aplasia/Hypoplasia of the brainstem (HP:0007362)1.69414099
153Lipid accumulation in hepatocytes (HP:0006561)1.69077833
154Prominent nasal bridge (HP:0000426)1.68849666
155Dandy-Walker malformation (HP:0001305)1.68528449
156Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.68227507
157Abnormal protein N-linked glycosylation (HP:0012347)1.68227507
158Abnormal protein glycosylation (HP:0012346)1.68227507
159Abnormal glycosylation (HP:0012345)1.68227507
160Abnormality of salivation (HP:0100755)1.68097697
161Limb dystonia (HP:0002451)1.68031295
162Abnormal respiratory motile cilium physiology (HP:0012261)1.67900854
163Patellar aplasia (HP:0006443)1.67522606
164Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.66957295
165Type 2 muscle fiber atrophy (HP:0003554)1.66482512
166Concave nail (HP:0001598)1.65991346
167Abnormality of the corticospinal tract (HP:0002492)1.65894263
168Absent radius (HP:0003974)1.65630630
169Scrotal hypoplasia (HP:0000046)1.65623136
170Sensory axonal neuropathy (HP:0003390)1.64739043
171Type II lissencephaly (HP:0007260)1.63711256
172Male pseudohermaphroditism (HP:0000037)1.62788851
173Cupped ear (HP:0000378)1.62786336
174Aplasia involving forearm bones (HP:0009822)1.61527733

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.38264808
2CASK3.77994615
3TRIM283.49749030
4TNIK3.35805791
5MAP4K23.09512015
6MUSK2.52443300
7MAP2K72.40000955
8VRK12.35635984
9MAP3K122.25374433
10AKT32.15561853
11ERBB31.98172617
12MKNK21.97823510
13PNCK1.94602284
14BUB11.84289987
15FRK1.81929673
16EPHA31.73322533
17BMPR1B1.65259970
18CAMKK21.62340874
19CDK191.61043987
20MKNK11.60025773
21SRPK11.58140020
22WEE11.52252955
23MST41.43959161
24EPHA41.43274146
25NME11.42128075
26TLK11.42108285
27TXK1.40118304
28ADRBK21.35301712
29CCNB11.29806405
30RPS6KA41.29326772
31MAPK131.29303840
32MAPK151.28783839
33OXSR11.28616686
34PAK61.24211055
35EIF2AK31.20438839
36NUAK11.18726689
37PLK31.18617991
38PLK21.17011792
39MINK11.14600699
40PRKD31.13623967
41STK391.13595133
42TSSK61.12109483
43SIK21.10850337
44NEK61.07134713
45CSNK1G31.05151272
46CAMK2B1.05004419
47NEK11.04188405
48CLK11.00452336
49PAK31.00164125
50YES10.99458256
51DYRK20.99374888
52ZAK0.97938655
53BRD40.97763832
54ACVR1B0.97364501
55MAP3K40.94753780
56BMPR20.93534507
57BRAF0.91731713
58BRSK20.91245750
59NME20.89050553
60PRKCG0.87669188
61FES0.87345574
62UHMK10.85536443
63MAPKAPK50.83671757
64KIT0.83307954
65DAPK10.82924405
66PLK40.82420194
67MAP2K40.81576614
68NTRK30.79806656
69CDK50.79406516
70BCKDK0.79079478
71CHEK20.79003764
72CDK140.78809104
73CDK180.78169335
74CDK30.76533537
75EIF2AK10.73145246
76CDK11A0.71193985
77BCR0.71003595
78PRPF4B0.70849488
79CDK150.69317245
80CDK80.68094629
81LIMK10.67883728
82CSNK1G10.67761372
83KSR10.67259609
84DYRK30.66935653
85SIK30.66581054
86SGK4940.66227172
87SGK2230.66227172
88GRK50.63356506
89PKN10.62518104
90PLK10.62481943
91CAMK2A0.61946541
92MARK10.58319239
93GRK70.58003944
94CSNK1A1L0.57831234
95RPS6KA50.57289691
96IRAK40.57276544
97MYLK0.57223230
98TTK0.56957264
99EIF2AK20.56516989
100ATR0.56365212
101DYRK1A0.56296228
102CSNK1G20.55697617
103CAMK1G0.55476252
104CAMK2D0.55414824
105TNK20.54243682
106LATS10.53533766
107AURKA0.53251727
108CSNK2A20.52862897
109SGK20.52407052
110STK38L0.52173149
111CAMK2G0.52100218
112NLK0.51066188
113PIK3CG0.51015070
114CSNK1D0.50456030
115CAMK40.49824145
116ATM0.49270384
117LCK0.48369979
118CSNK1A10.48160663
119LYN0.45961416
120FGR0.45243809
121CSNK2A10.44791078
122FGFR20.44517429
123ARAF0.44155889
124RAF10.43754872
125DYRK1B0.43713793
126NTRK20.42047434
127PRKCE0.41694703
128ERBB40.41460276
129TEC0.41298449
130PRKCZ0.40969483
131PBK0.39573885
132PINK10.38873617
133CDC70.38731336
134WNK30.38028174
135PASK0.37345992
136CDK70.37034178
137PRKDC0.36826742
138PRKAA10.36666024
139MAP3K50.36653155
140PRKACB0.36158755
141BRSK10.34284085
142RPS6KB10.34130129
143GRK10.32083143
144DAPK20.29804151
145CHEK10.29778634
146CSNK1E0.29034576

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.09414689
2RNA polymerase_Homo sapiens_hsa030203.75309506
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.21153134
4Oxidative phosphorylation_Homo sapiens_hsa001903.15336750
5Steroid biosynthesis_Homo sapiens_hsa001002.81734223
6Parkinsons disease_Homo sapiens_hsa050122.53287919
7Proteasome_Homo sapiens_hsa030502.51322214
8Homologous recombination_Homo sapiens_hsa034402.41115486
9Mismatch repair_Homo sapiens_hsa034302.38790029
10Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.36001910
11Protein export_Homo sapiens_hsa030602.32630364
12Spliceosome_Homo sapiens_hsa030402.27250544
13Nicotine addiction_Homo sapiens_hsa050332.25266627
14Basal transcription factors_Homo sapiens_hsa030222.23437667
15Butanoate metabolism_Homo sapiens_hsa006502.20422586
16Nucleotide excision repair_Homo sapiens_hsa034202.14726608
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.14645031
18Non-homologous end-joining_Homo sapiens_hsa034502.09506181
19Huntingtons disease_Homo sapiens_hsa050162.07494664
20Alzheimers disease_Homo sapiens_hsa050102.03424404
21DNA replication_Homo sapiens_hsa030302.03117898
22Propanoate metabolism_Homo sapiens_hsa006401.98628805
23Fanconi anemia pathway_Homo sapiens_hsa034601.91171605
24Pyrimidine metabolism_Homo sapiens_hsa002401.91076042
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.68502679
26Phototransduction_Homo sapiens_hsa047441.63146209
27Base excision repair_Homo sapiens_hsa034101.59178156
28Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.57980757
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.50318933
30Purine metabolism_Homo sapiens_hsa002301.43744175
31RNA degradation_Homo sapiens_hsa030181.43435421
32Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42751579
33Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34800963
34Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.34127517
35Primary immunodeficiency_Homo sapiens_hsa053401.30487021
36RNA transport_Homo sapiens_hsa030131.29317552
37Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.27337810
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.25397915
39Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.22942270
40Fatty acid metabolism_Homo sapiens_hsa012121.21750395
41Serotonergic synapse_Homo sapiens_hsa047261.18331417
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.15848747
43Collecting duct acid secretion_Homo sapiens_hsa049661.13364388
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.12914567
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.11045306
46Selenocompound metabolism_Homo sapiens_hsa004501.09667240
47Morphine addiction_Homo sapiens_hsa050321.05167360
48Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.03702099
49Fatty acid biosynthesis_Homo sapiens_hsa000611.03190385
50Amphetamine addiction_Homo sapiens_hsa050311.02202213
51Caffeine metabolism_Homo sapiens_hsa002321.01715957
52Taste transduction_Homo sapiens_hsa047421.01393019
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01382674
54Glutamatergic synapse_Homo sapiens_hsa047240.96419698
55Ether lipid metabolism_Homo sapiens_hsa005650.96399597
56Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.94326248
57Cardiac muscle contraction_Homo sapiens_hsa042600.93463809
58Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.89516454
59mRNA surveillance pathway_Homo sapiens_hsa030150.88635197
60Vitamin B6 metabolism_Homo sapiens_hsa007500.88522103
61Long-term depression_Homo sapiens_hsa047300.86560571
62Olfactory transduction_Homo sapiens_hsa047400.82012262
63SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81963156
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.80510244
65Circadian entrainment_Homo sapiens_hsa047130.79403854
66GABAergic synapse_Homo sapiens_hsa047270.78931128
67Cell cycle_Homo sapiens_hsa041100.78678480
68Hippo signaling pathway_Homo sapiens_hsa043900.77833158
69Autoimmune thyroid disease_Homo sapiens_hsa053200.75635546
70Fatty acid elongation_Homo sapiens_hsa000620.75181303
71Dopaminergic synapse_Homo sapiens_hsa047280.74619717
72Long-term potentiation_Homo sapiens_hsa047200.73414475
73Lysine degradation_Homo sapiens_hsa003100.72850696
74Gap junction_Homo sapiens_hsa045400.72721166
75Sphingolipid metabolism_Homo sapiens_hsa006000.68866678
76Cocaine addiction_Homo sapiens_hsa050300.68416363
77Primary bile acid biosynthesis_Homo sapiens_hsa001200.67865279
78beta-Alanine metabolism_Homo sapiens_hsa004100.64136467
79Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.61910063
80Arachidonic acid metabolism_Homo sapiens_hsa005900.60361913
81Oocyte meiosis_Homo sapiens_hsa041140.59716531
82Alcoholism_Homo sapiens_hsa050340.58874852
83Peroxisome_Homo sapiens_hsa041460.58667545
84Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58543835
85Hedgehog signaling pathway_Homo sapiens_hsa043400.57943847
86Colorectal cancer_Homo sapiens_hsa052100.55879759
87Vibrio cholerae infection_Homo sapiens_hsa051100.55718111
88Calcium signaling pathway_Homo sapiens_hsa040200.55488235
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55158532
90Synaptic vesicle cycle_Homo sapiens_hsa047210.54474667
91Epstein-Barr virus infection_Homo sapiens_hsa051690.53453843
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.52424431
93Allograft rejection_Homo sapiens_hsa053300.52355919
94Rheumatoid arthritis_Homo sapiens_hsa053230.50606729
95Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.50455278
96Regulation of autophagy_Homo sapiens_hsa041400.48302184
97Basal cell carcinoma_Homo sapiens_hsa052170.48091254
98AMPK signaling pathway_Homo sapiens_hsa041520.47548705
99Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45929297
100Linoleic acid metabolism_Homo sapiens_hsa005910.44926715
101Cysteine and methionine metabolism_Homo sapiens_hsa002700.44807052
102Fatty acid degradation_Homo sapiens_hsa000710.41400872
103Metabolic pathways_Homo sapiens_hsa011000.40828033
104Axon guidance_Homo sapiens_hsa043600.40309777
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.40245427
106cAMP signaling pathway_Homo sapiens_hsa040240.39975961
107TGF-beta signaling pathway_Homo sapiens_hsa043500.39694484
108Pyruvate metabolism_Homo sapiens_hsa006200.37564106
109Cholinergic synapse_Homo sapiens_hsa047250.37477068
110Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36942328
111Intestinal immune network for IgA production_Homo sapiens_hsa046720.36732473
112Asthma_Homo sapiens_hsa053100.36219233
113Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.35914658
114Tryptophan metabolism_Homo sapiens_hsa003800.35717533
115Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.35674509
116Hematopoietic cell lineage_Homo sapiens_hsa046400.34022186
117Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.33815611
118Salivary secretion_Homo sapiens_hsa049700.33399911
119Wnt signaling pathway_Homo sapiens_hsa043100.31673173
120T cell receptor signaling pathway_Homo sapiens_hsa046600.31226290
121Sulfur relay system_Homo sapiens_hsa041220.30566193
122Folate biosynthesis_Homo sapiens_hsa007900.29867728
123Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.27948335
124Renin secretion_Homo sapiens_hsa049240.27675887
125Circadian rhythm_Homo sapiens_hsa047100.25720632
126Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.25515093
127p53 signaling pathway_Homo sapiens_hsa041150.25328983
128Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.25303121
129Herpes simplex infection_Homo sapiens_hsa051680.25142810
130alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.23661718
131Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.23592928
132Ras signaling pathway_Homo sapiens_hsa040140.22968202
133Oxytocin signaling pathway_Homo sapiens_hsa049210.22183424
134Vascular smooth muscle contraction_Homo sapiens_hsa042700.22171811
135Insulin secretion_Homo sapiens_hsa049110.20707128
136Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.18598890

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