ZFP14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1central nervous system myelination (GO:0022010)9.22712475
2axon ensheathment in central nervous system (GO:0032291)9.22712475
3fatty acid elongation (GO:0030497)6.30413092
4myelination (GO:0042552)5.55276874
5long-chain fatty acid biosynthetic process (GO:0042759)5.50071373
6axon ensheathment (GO:0008366)5.47617947
7ensheathment of neurons (GO:0007272)5.47617947
8behavioral response to nicotine (GO:0035095)5.20087060
9establishment of mitochondrion localization (GO:0051654)4.76204074
10negative regulation of neurotransmitter transport (GO:0051589)4.72181190
11negative regulation of neurotransmitter secretion (GO:0046929)4.63919456
12pyrimidine nucleobase catabolic process (GO:0006208)4.58678931
13cholesterol biosynthetic process (GO:0006695)4.57537658
14presynaptic membrane organization (GO:0097090)4.48391213
15presynaptic membrane assembly (GO:0097105)4.22277102
16neuron cell-cell adhesion (GO:0007158)4.09652388
17sterol biosynthetic process (GO:0016126)4.05293465
18epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.03909723
19regulation of collateral sprouting (GO:0048670)3.90627235
20negative regulation of protein localization to cell surface (GO:2000009)3.86328229
21nucleobase catabolic process (GO:0046113)3.85555232
22isoprenoid biosynthetic process (GO:0008299)3.83016660
23gamma-aminobutyric acid transport (GO:0015812)3.82077350
24photoreceptor cell differentiation (GO:0046530)3.80616999
25eye photoreceptor cell differentiation (GO:0001754)3.80616999
26auditory behavior (GO:0031223)3.79595359
27neural tube formation (GO:0001841)3.77668449
28L-amino acid import (GO:0043092)3.76194839
29oligodendrocyte differentiation (GO:0048709)3.75633295
30mechanosensory behavior (GO:0007638)3.66605465
31fucose catabolic process (GO:0019317)3.64051150
32L-fucose metabolic process (GO:0042354)3.64051150
33L-fucose catabolic process (GO:0042355)3.64051150
34apical protein localization (GO:0045176)3.61649881
35nonmotile primary cilium assembly (GO:0035058)3.53929139
36glycerophospholipid catabolic process (GO:0046475)3.51486885
37epithelial cilium movement (GO:0003351)3.47212495
38negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.46813174
39positive regulation of action potential (GO:0045760)3.46429691
40transmission of nerve impulse (GO:0019226)3.43643703
41astrocyte development (GO:0014002)3.42869900
42substantia nigra development (GO:0021762)3.38103982
43neuronal action potential propagation (GO:0019227)3.36051817
44myelin maintenance (GO:0043217)3.28604589
45response to pheromone (GO:0019236)3.25201886
46long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.24490440
47neuron recognition (GO:0008038)3.23701477
48postsynaptic membrane organization (GO:0001941)3.22320265
49kidney morphogenesis (GO:0060993)3.22226640
50long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.21837236
51asymmetric protein localization (GO:0008105)3.15558276
52negative regulation of cytosolic calcium ion concentration (GO:0051481)3.13859146
53cerebral cortex radially oriented cell migration (GO:0021799)3.12509789
54response to methylmercury (GO:0051597)3.11602390
55synaptic vesicle exocytosis (GO:0016079)3.09877028
56positive regulation of oligodendrocyte differentiation (GO:0048714)3.07427135
57response to lipoprotein particle (GO:0055094)3.06036723
58regulation of cilium movement (GO:0003352)3.05301952
59axonal fasciculation (GO:0007413)3.04807363
60cilium movement (GO:0003341)3.04370155
61adult walking behavior (GO:0007628)3.03062562
62protein localization to synapse (GO:0035418)3.02530654
63negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.02062544
64protein localization to cilium (GO:0061512)3.01606401
65detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.00545117
66indolalkylamine metabolic process (GO:0006586)3.00201508
67limb bud formation (GO:0060174)2.99607233
68tryptophan catabolic process (GO:0006569)2.98572113
69indole-containing compound catabolic process (GO:0042436)2.98572113
70indolalkylamine catabolic process (GO:0046218)2.98572113
71protein polyglutamylation (GO:0018095)2.98558916
72axoneme assembly (GO:0035082)2.98127062
73neuronal ion channel clustering (GO:0045161)2.97045944
74negative regulation of axonogenesis (GO:0050771)2.96687867
75retinal cone cell development (GO:0046549)2.96422214
76startle response (GO:0001964)2.95326876
77cilium organization (GO:0044782)2.93741342
78membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.92991322
79cilium morphogenesis (GO:0060271)2.87378517
80cilium assembly (GO:0042384)2.87180156
81detection of light stimulus involved in visual perception (GO:0050908)2.83821573
82detection of light stimulus involved in sensory perception (GO:0050962)2.83821573
83creatine metabolic process (GO:0006600)2.83156011
84establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.83146708
85mitochondrion transport along microtubule (GO:0047497)2.83146708
86ionotropic glutamate receptor signaling pathway (GO:0035235)2.83065472
87regulation of action potential (GO:0098900)2.82044306
88behavioral response to ethanol (GO:0048149)2.81235832
89membrane tubulation (GO:0097320)2.81199775
90amino acid import (GO:0043090)2.81072460
91glutamate receptor signaling pathway (GO:0007215)2.80993750
92fatty-acyl-CoA biosynthetic process (GO:0046949)2.80567727
93somite development (GO:0061053)2.80324960
94kynurenine metabolic process (GO:0070189)2.79918265
95neurotransmitter uptake (GO:0001504)2.78948294
96G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.78922096
97intraciliary transport (GO:0042073)2.78042901
98L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.77625293
99regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.77398123
100ER overload response (GO:0006983)2.77267786
101mannosylation (GO:0097502)2.76627343
102platelet dense granule organization (GO:0060155)2.75392096
103fatty-acyl-CoA metabolic process (GO:0035337)2.75326533
104gamma-aminobutyric acid signaling pathway (GO:0007214)2.74545409
105dendritic spine morphogenesis (GO:0060997)2.74263306
106mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.72853712
107retinal ganglion cell axon guidance (GO:0031290)2.72398066
108protein palmitoylation (GO:0018345)2.72279225
109response to redox state (GO:0051775)2.70824816
110spinal cord motor neuron differentiation (GO:0021522)2.70160594
111neuronal action potential (GO:0019228)2.69361988
112response to auditory stimulus (GO:0010996)2.65891763
113water-soluble vitamin biosynthetic process (GO:0042364)2.65834998
114mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.65805405
115cAMP catabolic process (GO:0006198)2.64492455
116negative regulation of synaptic transmission, GABAergic (GO:0032229)2.64257734
117reflex (GO:0060004)2.62434894
118tryptophan metabolic process (GO:0006568)2.62310471
119negative regulation of translation, ncRNA-mediated (GO:0040033)2.61815067
120regulation of translation, ncRNA-mediated (GO:0045974)2.61815067
121negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.61815067
122regulation of telomere maintenance (GO:0032204)2.61649296
123photoreceptor cell maintenance (GO:0045494)2.61562891
124cilium or flagellum-dependent cell motility (GO:0001539)2.61272357
125amyloid precursor protein metabolic process (GO:0042982)2.61020830
126myelination in peripheral nervous system (GO:0022011)2.59931890
127peripheral nervous system axon ensheathment (GO:0032292)2.59931890
128regulation of synaptic vesicle exocytosis (GO:2000300)2.59481935
129negative regulation of synaptic transmission (GO:0050805)2.58326837
130negative regulation of transcription regulatory region DNA binding (GO:2000678)2.58000165
131membrane assembly (GO:0071709)2.57939248
132protein neddylation (GO:0045116)2.57455965
133regulation of glucokinase activity (GO:0033131)2.56959628
134regulation of hexokinase activity (GO:1903299)2.56959628
135inner ear receptor stereocilium organization (GO:0060122)2.56958578
136response to epinephrine (GO:0071871)2.56320244
137nerve growth factor signaling pathway (GO:0038180)2.55882806
138negative regulation of axon extension (GO:0030517)2.55824632
139synapse assembly (GO:0007416)2.55743079
140nucleotide transmembrane transport (GO:1901679)2.55026117
141negative regulation of telomere maintenance (GO:0032205)2.54996788
142primary amino compound metabolic process (GO:1901160)2.54561269
143neuron-neuron synaptic transmission (GO:0007270)2.54178633
144protein-cofactor linkage (GO:0018065)2.53645599
145neuron remodeling (GO:0016322)2.52924600
146vocalization behavior (GO:0071625)2.52830511
147regulation of catecholamine metabolic process (GO:0042069)2.52486144
148regulation of dopamine metabolic process (GO:0042053)2.52486144
149neural nucleus development (GO:0048857)2.51837977
150protein complex biogenesis (GO:0070271)2.51490631
151positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.51416762
152synaptic transmission, glutamatergic (GO:0035249)2.50081612
153synaptic vesicle maturation (GO:0016188)2.49880311
154synaptic transmission, cholinergic (GO:0007271)2.49730773
155positive regulation of synapse assembly (GO:0051965)2.49178298
156indole-containing compound metabolic process (GO:0042430)2.48730008
157membrane depolarization during action potential (GO:0086010)2.48352722
158glial cell development (GO:0021782)2.48024723
159response to catecholamine (GO:0071869)2.47702088
160response to monoamine (GO:0071867)2.47702088
161peripheral nervous system development (GO:0007422)2.47464118
162dendrite morphogenesis (GO:0048813)2.47209563
163Golgi to endosome transport (GO:0006895)2.47162578
164mitochondrial respiratory chain complex I assembly (GO:0032981)2.46829408
165NADH dehydrogenase complex assembly (GO:0010257)2.46829408
166mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.46829408
167appendage development (GO:0048736)2.46487892
168limb development (GO:0060173)2.46487892
169cornea development in camera-type eye (GO:0061303)2.46174421
170dendrite development (GO:0016358)2.46108948
171spinal cord development (GO:0021510)2.46040679
172head development (GO:0060322)2.45929016
173axon development (GO:0061564)2.45329302
174negative regulation of mast cell activation (GO:0033004)2.45320801
175cerebellar granule cell differentiation (GO:0021707)2.45074041
176photoreceptor cell development (GO:0042461)2.44436524
177serotonin metabolic process (GO:0042428)2.42051398
178sulfation (GO:0051923)2.41726671
179cellular ketone body metabolic process (GO:0046950)2.40822391
180olfactory bulb development (GO:0021772)2.40412553
181glycosphingolipid biosynthetic process (GO:0006688)2.40249330

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.88299576
2EZH2_22144423_ChIP-Seq_EOC_Human3.67255962
3TAF15_26573619_Chip-Seq_HEK293_Human2.72819210
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.61417491
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.58248223
6SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.51599464
7IGF1R_20145208_ChIP-Seq_DFB_Human2.51360604
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.39187491
9ZFP57_27257070_Chip-Seq_ESCs_Mouse2.38327580
10VDR_22108803_ChIP-Seq_LS180_Human2.36108637
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.32169422
12MTF2_20144788_ChIP-Seq_MESCs_Mouse2.10805587
13RNF2_18974828_ChIP-Seq_MESCs_Mouse2.06339064
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.06339064
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.05645350
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.05320111
17OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.04767625
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.04091635
19SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.03856909
20SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.01760718
21SALL1_21062744_ChIP-ChIP_HESCs_Human2.01332599
22AR_21572438_ChIP-Seq_LNCaP_Human2.00477670
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.99308979
24EED_16625203_ChIP-ChIP_MESCs_Mouse1.98513702
25HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97974001
26CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.96239458
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.95113736
28EZH2_27294783_Chip-Seq_ESCs_Mouse1.94265058
29POU3F2_20337985_ChIP-ChIP_501MEL_Human1.93049163
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.92636612
31JARID2_20075857_ChIP-Seq_MESCs_Mouse1.91160285
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.89523933
33RNF2_27304074_Chip-Seq_ESCs_Mouse1.84988252
34ER_23166858_ChIP-Seq_MCF-7_Human1.81333046
35VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.77795402
36ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77278192
37P300_19829295_ChIP-Seq_ESCs_Human1.77269083
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.74696597
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.73789272
40SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.62472765
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.61169606
42CBX2_27304074_Chip-Seq_ESCs_Mouse1.61150109
43FUS_26573619_Chip-Seq_HEK293_Human1.60898910
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.60271405
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.58813569
46BCAT_22108803_ChIP-Seq_LS180_Human1.58785611
47TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.58647221
48REST_21632747_ChIP-Seq_MESCs_Mouse1.57424662
49DROSHA_22980978_ChIP-Seq_HELA_Human1.55758539
50* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.55525105
51* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.55525105
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.55211393
53HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.51817266
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50356398
55CBP_20019798_ChIP-Seq_JUKART_Human1.50356398
56PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.46917342
57SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.45804169
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44779717
59SMAD4_21799915_ChIP-Seq_A2780_Human1.44115715
60CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42164179
61RARB_27405468_Chip-Seq_BRAIN_Mouse1.41881040
62TOP2B_26459242_ChIP-Seq_MCF-7_Human1.41880952
63RNF2_27304074_Chip-Seq_NSC_Mouse1.40724740
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.39153145
65STAT3_23295773_ChIP-Seq_U87_Human1.34892910
66REST_18959480_ChIP-ChIP_MESCs_Mouse1.31941269
67PCGF2_27294783_Chip-Seq_NPCs_Mouse1.31265814
68TP53_22573176_ChIP-Seq_HFKS_Human1.29309419
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28601112
70TCF4_22108803_ChIP-Seq_LS180_Human1.28449351
71EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.28141964
72CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.27323608
73SUZ12_27294783_Chip-Seq_NPCs_Mouse1.26977137
74IRF1_19129219_ChIP-ChIP_H3396_Human1.26860214
75TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.25476457
76AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24510026
77TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23751911
78TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23597617
79* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.23535035
80SOX2_21211035_ChIP-Seq_LN229_Gbm1.22734205
81UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.22224763
82POU5F1_16153702_ChIP-ChIP_HESCs_Human1.21800212
83NANOG_18555785_Chip-Seq_ESCs_Mouse1.21785464
84KLF5_20875108_ChIP-Seq_MESCs_Mouse1.21283797
85E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.20565975
86GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20537702
87FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.19988027
88P53_22127205_ChIP-Seq_FIBROBLAST_Human1.18892160
89EZH2_27294783_Chip-Seq_NPCs_Mouse1.18550657
90FLI1_21867929_ChIP-Seq_TH2_Mouse1.18524139
91NFE2_27457419_Chip-Seq_LIVER_Mouse1.16036549
92PRDM14_20953172_ChIP-Seq_ESCs_Human1.15989184
93ARNT_22903824_ChIP-Seq_MCF-7_Human1.15389241
94TAL1_26923725_Chip-Seq_HPCs_Mouse1.14884739
95NOTCH1_21737748_ChIP-Seq_TLL_Human1.14438019
96CMYC_18555785_Chip-Seq_ESCs_Mouse1.13947280
97TCF4_23295773_ChIP-Seq_U87_Human1.13423286
98WT1_19549856_ChIP-ChIP_CCG9911_Human1.12856034
99MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.11756208
100AR_25329375_ChIP-Seq_VCAP_Human1.10342896
101SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10182475
102NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.09920383
103TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.09832798
104EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09633086
105MYC_18940864_ChIP-ChIP_HL60_Human1.09110044
106RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08797837
107SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.05664080
108KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05173749
109E2F1_18555785_Chip-Seq_ESCs_Mouse1.04933105
110MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04853795
111CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04710757
112NR3C1_21868756_ChIP-Seq_MCF10A_Human1.04696091
113NR3C1_23031785_ChIP-Seq_PC12_Mouse1.04641331
114CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.04503530
115SMAD4_21741376_ChIP-Seq_EPCs_Human1.02082593
116RUNX2_22187159_ChIP-Seq_PCA_Human1.01606120
117FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00567497
118FOXA1_25329375_ChIP-Seq_VCAP_Human1.00567497
119SOX9_26525672_Chip-Seq_HEART_Mouse1.00398657
120NRF2_20460467_ChIP-Seq_MEFs_Mouse1.00375478
121NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.00375478
122RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00325215
123* ETV2_25802403_ChIP-Seq_MESCs_Mouse0.99711117
124P300_18555785_Chip-Seq_ESCs_Mouse0.99164407
125ZNF217_24962896_ChIP-Seq_MCF-7_Human0.98552664
126FOXA1_21572438_ChIP-Seq_LNCaP_Human0.98441389
127P53_22387025_ChIP-Seq_ESCs_Mouse0.98002729
128PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97166863
129AHR_22903824_ChIP-Seq_MCF-7_Human0.97154008
130HTT_18923047_ChIP-ChIP_STHdh_Human0.96970457
131EP300_21415370_ChIP-Seq_HL-1_Mouse0.96786045
132EWS_26573619_Chip-Seq_HEK293_Human0.95824405
133CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.94755507
134ZNF274_21170338_ChIP-Seq_K562_Hela0.94042901
135LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93145034
136SOX2_19829295_ChIP-Seq_ESCs_Human0.93100481
137NANOG_19829295_ChIP-Seq_ESCs_Human0.93100481
138PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92958620
139WT1_25993318_ChIP-Seq_PODOCYTE_Human0.92827754

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.06439359
2MP0000920_abnormal_myelination4.03557074
3MP0004270_analgesia3.72285755
4MP0004859_abnormal_synaptic_plasticity3.48639904
5MP0001529_abnormal_vocalization3.38720030
6MP0003950_abnormal_plasma_membrane2.78324540
7MP0008877_abnormal_DNA_methylation2.75193848
8MP0000569_abnormal_digit_pigmentation2.70368462
9MP0003635_abnormal_synaptic_transmissio2.65598293
10MP0002064_seizures2.62994751
11MP0001486_abnormal_startle_reflex2.62344334
12MP0002272_abnormal_nervous_system2.62311026
13MP0005409_darkened_coat_color2.55016697
14MP0003329_amyloid_beta_deposits2.43887865
15MP0001905_abnormal_dopamine_level2.36585462
16MP0009745_abnormal_behavioral_response2.30669022
17MP0000778_abnormal_nervous_system2.30136937
18MP0006292_abnormal_olfactory_placode2.20654704
19MP0003690_abnormal_glial_cell2.17298254
20MP0004142_abnormal_muscle_tone2.12020323
21MP0002102_abnormal_ear_morphology2.10502672
22MP0009046_muscle_twitch2.08517478
23MP0002063_abnormal_learning/memory/cond2.05377855
24MP0005423_abnormal_somatic_nervous2.04919341
25MP0002572_abnormal_emotion/affect_behav2.04118455
26MP0003136_yellow_coat_color2.02276002
27MP0002734_abnormal_mechanical_nocicepti1.99961763
28MP0004742_abnormal_vestibular_system1.96595014
29MP0003634_abnormal_glial_cell1.94994460
30MP0002638_abnormal_pupillary_reflex1.94823308
31MP0005171_absent_coat_pigmentation1.94775177
32MP0002653_abnormal_ependyma_morphology1.85834192
33MP0004133_heterotaxia1.82038161
34MP0004885_abnormal_endolymph1.79719250
35MP0001968_abnormal_touch/_nociception1.75068031
36MP0003121_genomic_imprinting1.73658721
37MP0005551_abnormal_eye_electrophysiolog1.72885812
38MP0008569_lethality_at_weaning1.65966154
39MP0002229_neurodegeneration1.65415024
40MP0005646_abnormal_pituitary_gland1.63054794
41MP0002067_abnormal_sensory_capabilities1.61690240
42MP0000955_abnormal_spinal_cord1.60605122
43MP0000566_synostosis1.59295158
44MP0004924_abnormal_behavior1.56107119
45MP0005386_behavior/neurological_phenoty1.56107119
46MP0003632_abnormal_nervous_system1.55577029
47MP0002882_abnormal_neuron_morphology1.48819892
48MP0001485_abnormal_pinna_reflex1.46476165
49MP0001970_abnormal_pain_threshold1.43772399
50MP0002736_abnormal_nociception_after1.41836418
51MP0003890_abnormal_embryonic-extraembry1.41699314
52MP0001440_abnormal_grooming_behavior1.41297051
53MP0002066_abnormal_motor_capabilities/c1.37329225
54MP0002733_abnormal_thermal_nociception1.35943143
55MP0001986_abnormal_taste_sensitivity1.35173024
56MP0004043_abnormal_pH_regulation1.34683562
57MP0005645_abnormal_hypothalamus_physiol1.34197428
58MP0003122_maternal_imprinting1.33066308
59MP0003631_nervous_system_phenotype1.31971081
60MP0004134_abnormal_chest_morphology1.31851523
61MP0003011_delayed_dark_adaptation1.30571563
62MP0008872_abnormal_physiological_respon1.30473652
63MP0000427_abnormal_hair_cycle1.29939998
64MP0002735_abnormal_chemical_nociception1.28784269
65MP0006276_abnormal_autonomic_nervous1.28661612
66MP0000462_abnormal_digestive_system1.26723399
67MP0008789_abnormal_olfactory_epithelium1.22265507
68MP0001293_anophthalmia1.19232934
69MP0003633_abnormal_nervous_system1.19212415
70MP0009780_abnormal_chondrocyte_physiolo1.18641995
71MP0005410_abnormal_fertilization1.18208146
72MP0002184_abnormal_innervation1.18076194
73MP0002822_catalepsy1.17345957
74MP0002928_abnormal_bile_duct1.16397326
75MP0005174_abnormal_tail_pigmentation1.16327665
76MP0006072_abnormal_retinal_apoptosis1.15822489
77MP0002557_abnormal_social/conspecific_i1.15620000
78MP0002751_abnormal_autonomic_nervous1.14381252
79MP0004145_abnormal_muscle_electrophysio1.12964740
80MP0003787_abnormal_imprinting1.11413266
81MP0000604_amyloidosis1.11072580
82MP0003119_abnormal_digestive_system1.10269958
83MP0002752_abnormal_somatic_nervous1.09678790
84MP0010678_abnormal_skin_adnexa1.09037092
85MP0005394_taste/olfaction_phenotype1.07996988
86MP0005499_abnormal_olfactory_system1.07996988
87MP0002909_abnormal_adrenal_gland1.07002591
88MP0000631_abnormal_neuroendocrine_gland1.06407937
89MP0000383_abnormal_hair_follicle1.05941191
90MP0002152_abnormal_brain_morphology1.04825681
91MP0008875_abnormal_xenobiotic_pharmacok1.04078191
92MP0001963_abnormal_hearing_physiology1.03986692
93MP0003646_muscle_fatigue1.03971287
94MP0001501_abnormal_sleep_pattern1.03794806
95MP0005084_abnormal_gallbladder_morpholo1.03750089
96MP0001502_abnormal_circadian_rhythm1.00261141
97MP0004147_increased_porphyrin_level0.97600326
98MP0004811_abnormal_neuron_physiology0.97254164
99MP0003137_abnormal_impulse_conducting0.96914482
100MP0003878_abnormal_ear_physiology0.96858960
101MP0005377_hearing/vestibular/ear_phenot0.96858960
102MP0005195_abnormal_posterior_eye0.96588324
103MP0002160_abnormal_reproductive_system0.95314695
104MP0002876_abnormal_thyroid_physiology0.94227513
105MP0005253_abnormal_eye_physiology0.93616881
106MP0004381_abnormal_hair_follicle0.92871179
107MP0004215_abnormal_myocardial_fiber0.91496927
108MP0000751_myopathy0.89897967
109MP0002234_abnormal_pharynx_morphology0.89546128
110MP0001984_abnormal_olfaction0.89378341
111MP0005389_reproductive_system_phenotype0.88668405
112MP0005391_vision/eye_phenotype0.88652519
113MP0001177_atelectasis0.87236101
114MP0004036_abnormal_muscle_relaxation0.87055220
115MP0002233_abnormal_nose_morphology0.86985555
116MP0001919_abnormal_reproductive_system0.86316011
117MP0010386_abnormal_urinary_bladder0.83012964
118MP0001299_abnormal_eye_distance/0.82605904
119MP0000049_abnormal_middle_ear0.81843275
120MP0005187_abnormal_penis_morphology0.81715913
121MP0000372_irregular_coat_pigmentation0.80812830
122MP0001346_abnormal_lacrimal_gland0.79288895
123MP0008260_abnormal_autophagy0.78908627
124MP0001188_hyperpigmentation0.78094899
125MP0002090_abnormal_vision0.77456140
126MP0000537_abnormal_urethra_morphology0.77051931
127MP0000026_abnormal_inner_ear0.76694283
128MP0000647_abnormal_sebaceous_gland0.75481272
129MP0005623_abnormal_meninges_morphology0.72372821
130MP0003938_abnormal_ear_development0.71203644
131MP0003195_calcinosis0.71141541
132MP0003937_abnormal_limbs/digits/tail_de0.67743294
133MP0002069_abnormal_eating/drinking_beha0.67356637
134MP0004085_abnormal_heartbeat0.66420238
135MP0002938_white_spotting0.64455634
136MP0001661_extended_life_span0.64067391
137MP0000747_muscle_weakness0.62052621
138MP0002837_dystrophic_cardiac_calcinosis0.60825719
139MP0003861_abnormal_nervous_system0.60605573

Predicted human phenotypes

RankGene SetZ-score
1Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.67867502
2Degeneration of the lateral corticospinal tracts (HP:0002314)6.67867502
3Neurofibrillary tangles (HP:0002185)5.58487566
4Abnormality of the corticospinal tract (HP:0002492)5.22241221
5Parakeratosis (HP:0001036)4.42034011
6Pancreatic cysts (HP:0001737)4.35484130
7True hermaphroditism (HP:0010459)4.10366744
8Cerebral inclusion bodies (HP:0100314)4.08763603
9Pancreatic fibrosis (HP:0100732)4.07264979
10Molar tooth sign on MRI (HP:0002419)4.01674892
11Abnormality of midbrain morphology (HP:0002418)4.01674892
12Spastic gait (HP:0002064)3.80756838
13Supranuclear gaze palsy (HP:0000605)3.70554317
14Focal motor seizures (HP:0011153)3.63157725
15Nephronophthisis (HP:0000090)3.60013825
16Increased serum pyruvate (HP:0003542)3.56557287
17Abnormality of glycolysis (HP:0004366)3.56557287
18Myokymia (HP:0002411)3.28591062
19Retinal dysplasia (HP:0007973)3.26569460
20Insidious onset (HP:0003587)3.22985495
21Termporal pattern (HP:0011008)3.22985495
22Abnormality of the renal medulla (HP:0100957)3.19490612
23Pheochromocytoma (HP:0002666)3.19000190
24Peripheral hypomyelination (HP:0007182)3.12630524
25Scanning speech (HP:0002168)3.11673595
26Truncal ataxia (HP:0002078)3.10208517
27Sensory axonal neuropathy (HP:0003390)3.05526192
28Cerebral hypomyelination (HP:0006808)3.02033772
29Dysmetria (HP:0001310)3.00021446
30Epileptic encephalopathy (HP:0200134)2.97900232
31Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.97823057
32Abnormality of the renal cortex (HP:0011035)2.94890791
33Congenital primary aphakia (HP:0007707)2.93443505
34Congenital stationary night blindness (HP:0007642)2.85736580
35Chronic hepatic failure (HP:0100626)2.84164210
36Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.83614186
37Hyperventilation (HP:0002883)2.81680336
38Methylmalonic acidemia (HP:0002912)2.77474574
39Neuroendocrine neoplasm (HP:0100634)2.76600617
40Ankle clonus (HP:0011448)2.74182490
41Leukodystrophy (HP:0002415)2.72637036
42Cystic liver disease (HP:0006706)2.69550270
43Intention tremor (HP:0002080)2.65839606
44Akinesia (HP:0002304)2.65689332
45Nephrogenic diabetes insipidus (HP:0009806)2.65243194
46Lower limb muscle weakness (HP:0007340)2.64361270
47Lissencephaly (HP:0001339)2.60029703
48Acute necrotizing encephalopathy (HP:0006965)2.53088655
49Onion bulb formation (HP:0003383)2.52202240
50Clumsiness (HP:0002312)2.51073712
51Atonic seizures (HP:0010819)2.42454099
52Partial agenesis of the corpus callosum (HP:0001338)2.42185884
53Genetic anticipation (HP:0003743)2.42146916
54Febrile seizures (HP:0002373)2.41589422
55Sclerocornea (HP:0000647)2.41397383
56Anteriorly placed anus (HP:0001545)2.40886341
57Tubular atrophy (HP:0000092)2.38684176
58Alacrima (HP:0000522)2.38170372
59Bile duct proliferation (HP:0001408)2.37544696
60Abnormal biliary tract physiology (HP:0012439)2.37544696
61Absent/shortened dynein arms (HP:0200106)2.35231694
62Dynein arm defect of respiratory motile cilia (HP:0012255)2.35231694
63Abolished electroretinogram (ERG) (HP:0000550)2.34957788
64Poor coordination (HP:0002370)2.30360127
65Polydipsia (HP:0001959)2.27173971
66Abnormal drinking behavior (HP:0030082)2.27173971
67Thickened helices (HP:0000391)2.27091732
68Anencephaly (HP:0002323)2.24089527
69Abnormality of the labia minora (HP:0012880)2.22365518
70Drooling (HP:0002307)2.22158711
71Focal seizures (HP:0007359)2.21196201
72Optic nerve hypoplasia (HP:0000609)2.20579803
73Inability to walk (HP:0002540)2.20513054
74Abnormal mitochondria in muscle tissue (HP:0008316)2.20104013
75Absent septum pellucidum (HP:0001331)2.19906267
76Morphological abnormality of the pyramidal tract (HP:0002062)2.19780849
77Abnormal rod and cone electroretinograms (HP:0008323)2.19471667
78Hypoplastic pelvis (HP:0008839)2.19392380
79Myelomeningocele (HP:0002475)2.17315539
80Generalized myoclonic seizures (HP:0002123)2.16815675
81Aplasia/Hypoplasia of the tongue (HP:0010295)2.16708947
82Cerebral hemorrhage (HP:0001342)2.16238142
83Renal cortical cysts (HP:0000803)2.15997332
84Hemiparesis (HP:0001269)2.15027366
85Pachygyria (HP:0001302)2.13495584
86Type II lissencephaly (HP:0007260)2.11995313
87Intestinal atresia (HP:0011100)2.11820062
88Congenital ichthyosiform erythroderma (HP:0007431)2.11432273
89Urinary urgency (HP:0000012)2.11391088
90Muscle hypertrophy of the lower extremities (HP:0008968)2.11162838
91Humeroradial synostosis (HP:0003041)2.11038954
92Synostosis involving the elbow (HP:0003938)2.11038954
93Attenuation of retinal blood vessels (HP:0007843)2.10843439
94Protruding tongue (HP:0010808)2.09352426
95Abnormal ciliary motility (HP:0012262)2.09060048
96Progressive macrocephaly (HP:0004481)2.08831839
97Pendular nystagmus (HP:0012043)2.08425639
98Progressive cerebellar ataxia (HP:0002073)2.07879009
99Cerebellar dysplasia (HP:0007033)2.07463667
100Limb dystonia (HP:0002451)2.06447966
101Abnormal auditory evoked potentials (HP:0006958)2.06169560
102Congenital hepatic fibrosis (HP:0002612)2.06019489
103Broad-based gait (HP:0002136)2.05013052
104Large for gestational age (HP:0001520)2.04488424
105CNS hypomyelination (HP:0003429)2.04429250
106Volvulus (HP:0002580)2.03839075
107Hyperalaninemia (HP:0003348)2.03281454
108Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.03281454
109Abnormality of alanine metabolism (HP:0010916)2.03281454
110Postaxial foot polydactyly (HP:0001830)2.03106652
111Slow saccadic eye movements (HP:0000514)2.01971597
112Postaxial hand polydactyly (HP:0001162)2.01557713
113Agitation (HP:0000713)2.01518610
114Excessive salivation (HP:0003781)2.00611097
115Dysdiadochokinesis (HP:0002075)2.00368561
116Aplasia/Hypoplasia of the tibia (HP:0005772)2.00034497
117Aplasia involving bones of the extremities (HP:0009825)1.99727681
118Aplasia involving bones of the upper limbs (HP:0009823)1.99727681
119Aplasia of the phalanges of the hand (HP:0009802)1.99727681
120Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.99721538
121Stridor (HP:0010307)1.99603929
122Acute encephalopathy (HP:0006846)1.99503175
123Abnormality of the septum pellucidum (HP:0007375)1.98877771
124Autoamputation (HP:0001218)1.98170518
125Male pseudohermaphroditism (HP:0000037)1.97630955
126Abnormal respiratory motile cilium morphology (HP:0005938)1.97335043
127Abnormal respiratory epithelium morphology (HP:0012253)1.97335043
128Decreased lacrimation (HP:0000633)1.95338638
129Abnormality of the phalanges of the 2nd finger (HP:0009541)1.94987175
130Mitochondrial inheritance (HP:0001427)1.94231605
131Septo-optic dysplasia (HP:0100842)1.93804998
132Specific learning disability (HP:0001328)1.93647792
133Vaginal atresia (HP:0000148)1.93529666
134Furrowed tongue (HP:0000221)1.93112135
135Postnatal microcephaly (HP:0005484)1.93097898
136Hypothermia (HP:0002045)1.92585072
137Megalencephaly (HP:0001355)1.92045141
138Progressive inability to walk (HP:0002505)1.91871874
139Renal Fanconi syndrome (HP:0001994)1.91080603
1403-Methylglutaconic aciduria (HP:0003535)1.90854189
141Narrow forehead (HP:0000341)1.90047990
142Congenital, generalized hypertrichosis (HP:0004540)1.89627346
143Oligodactyly (hands) (HP:0001180)1.89246113
144Gait imbalance (HP:0002141)1.89186401
145Absent rod-and cone-mediated responses on ERG (HP:0007688)1.87497714
146Genital tract atresia (HP:0001827)1.87184429
147Gaze-evoked nystagmus (HP:0000640)1.86566530
148Polyuria (HP:0000103)1.86215542
149Colon cancer (HP:0003003)1.84441616
150Anophthalmia (HP:0000528)1.83810802
151Clonus (HP:0002169)1.83800235
152Occipital encephalocele (HP:0002085)1.83047455
153Optic disc pallor (HP:0000543)1.81914321
154Urinary bladder sphincter dysfunction (HP:0002839)1.80506445
155Keratoconus (HP:0000563)1.80380291
156Increased corneal curvature (HP:0100692)1.80380291
157Blue irides (HP:0000635)1.79818622
158Polyphagia (HP:0002591)1.79728606
159Abnormal respiratory motile cilium physiology (HP:0012261)1.79498443
160Medial flaring of the eyebrow (HP:0010747)1.79470949
161Steppage gait (HP:0003376)1.79076793
162Premature skin wrinkling (HP:0100678)1.78695137
163Split foot (HP:0001839)1.78603718
164Fair hair (HP:0002286)1.78449827
165Increased circulating renin level (HP:0000848)1.78159745
166Cupped ear (HP:0000378)1.77435580
167Supernumerary spleens (HP:0009799)1.77133286
168Widely spaced teeth (HP:0000687)1.76821387
169Preaxial hand polydactyly (HP:0001177)1.75393727
170Spastic paraplegia (HP:0001258)1.75224407
171Esophageal atresia (HP:0002032)1.74584185
172Stomach cancer (HP:0012126)1.74356240
173Neuronal loss in central nervous system (HP:0002529)1.73796828
174Impaired vibration sensation in the lower limbs (HP:0002166)1.73112661
175Dandy-Walker malformation (HP:0001305)1.73017765
176Paraplegia (HP:0010550)1.72102880
177Anxiety (HP:0000739)1.71539906
178Patellar aplasia (HP:0006443)1.71329314
179Dialeptic seizures (HP:0011146)1.69960902
180Absent speech (HP:0001344)1.69492736
181Abnormal hair whorl (HP:0010721)1.68509528

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.94817150
2STK394.51216897
3OXSR13.62336084
4CASK2.98849728
5EPHB12.75110862
6MAP4K22.62928059
7BCR2.61093268
8UHMK12.53462223
9PKN12.35392229
10MARK12.28404762
11ADRBK22.26698836
12TNIK2.24255807
13PINK12.16685827
14CDK192.15134132
15ACVR1B2.08395395
16ZAK2.05181834
17PNCK1.99849543
18GRK11.88281901
19NUAK11.85352218
20MAPKAPK51.77953398
21WNK41.76289572
22CSNK1G31.68410947
23CAMK2B1.67745092
24MKNK21.66005810
25CSNK1A1L1.59728104
26SGK4941.59702480
27SGK2231.59702480
28EPHA41.59128056
29FGFR21.58948961
30NTRK21.58876154
31INSRR1.55478331
32LIMK11.50895684
33TAOK31.44539685
34CSNK1G21.44180528
35PRPF4B1.42317361
36ROCK21.41182069
37MET1.40963990
38WNK11.39994446
39CLK11.38358297
40PAK61.37363357
41NTRK31.37055460
42CAMKK21.34560636
43CSNK1G11.30849983
44DYRK21.29953527
45PBK1.28643539
46MAPK131.26657520
47MAPK151.24791631
48NEK61.22630292
49TIE11.22485569
50CAMK2D1.20432767
51NTRK11.19525128
52PAK31.11098784
53MUSK1.09263283
54CAMK2A1.09232704
55TLK11.08971025
56WNK31.07754770
57MAP2K71.06970133
58CDK51.06936462
59TGFBR11.05138464
60PHKG11.03477833
61PHKG21.03477833
62MARK21.03257574
63FGR1.02576790
64TRIM280.99895633
65MKNK10.98945989
66STK38L0.96018136
67CAMK2G0.94804910
68MST40.90513604
69BMPR1B0.88831539
70MAP3K40.88623950
71TYRO30.87665348
72PRKCE0.86487320
73MELK0.85620547
74TNK20.85022507
75SGK20.84138480
76ERBB30.83717671
77MINK10.82696384
78MAP2K40.80958103
79ADRBK10.80956834
80CAMK1G0.79094964
81CDK140.77862530
82TXK0.73343266
83GRK70.73290198
84PRKD10.70548699
85HIPK20.69902046
86PRKG10.69225772
87CDK150.67334011
88CDK180.67096034
89BMPR20.66014779
90VRK10.64855205
91PRKCQ0.63095289
92ICK0.62372642
93PLK20.61969133
94DYRK1A0.61102674
95FES0.60989533
96DYRK30.58376868
97CAMK10.57865977
98CDK11A0.56845033
99PRKCH0.56224700
100TESK20.55544888
101EIF2AK30.53936934
102IRAK10.52719176
103FYN0.52329175
104OBSCN0.51973963
105TEC0.51299344
106DMPK0.50895643
107PRKCZ0.50661444
108EPHA30.48889705
109MAP3K90.48543684
110BRSK20.47693154
111PRKCG0.47515437
112ERBB40.46078864
113SIK20.45163030
114PRKACB0.45000045
115STK110.44571681
116GSK3A0.44193436
117PTK2B0.43864767
118NLK0.43762928
119CAMKK10.43580368
120GRK50.43265601
121CSNK1A10.42633385
122PRKACA0.41927811
123SGK10.41822302
124STK160.41124393
125EPHB20.40514370
126PDGFRB0.40385335
127ARAF0.40237531
128RPS6KA50.39801480
129PIK3CA0.38859683
130PLK30.38846408
131CAMK40.38718168
132IRAK20.38420924
133AKT30.38193744
134ERBB20.37775330
135CDK30.37038241
136CAMK1D0.36550464
137CSNK1D0.36415400
138DAPK20.36089758
139BCKDK0.35608027
140PLK40.34819133
141BRD40.34632931
142MAPK100.34026277
143SRPK10.33710151
144ATM0.29329857
145NME10.27719724

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009004.83291244
2Steroid biosynthesis_Homo sapiens_hsa001003.90023730
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.69617141
4Fatty acid elongation_Homo sapiens_hsa000623.33001490
5Oxidative phosphorylation_Homo sapiens_hsa001902.38680931
6Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.33135938
7Ether lipid metabolism_Homo sapiens_hsa005652.32795340
8Nicotine addiction_Homo sapiens_hsa050332.22500424
9GABAergic synapse_Homo sapiens_hsa047272.16028968
10Nitrogen metabolism_Homo sapiens_hsa009102.12117975
11Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.04801656
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.03821508
13Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.98576012
14Glutamatergic synapse_Homo sapiens_hsa047241.97327280
15Parkinsons disease_Homo sapiens_hsa050121.94022597
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.90319383
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.84700387
18Butanoate metabolism_Homo sapiens_hsa006501.81333256
19Morphine addiction_Homo sapiens_hsa050321.79283396
20Alzheimers disease_Homo sapiens_hsa050101.77492427
21Axon guidance_Homo sapiens_hsa043601.76358649
22Basal transcription factors_Homo sapiens_hsa030221.75137516
23Serotonergic synapse_Homo sapiens_hsa047261.71183900
24Caffeine metabolism_Homo sapiens_hsa002321.71065105
25Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.66463505
26Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.66196479
27Collecting duct acid secretion_Homo sapiens_hsa049661.60178755
28Circadian entrainment_Homo sapiens_hsa047131.53795898
29Synaptic vesicle cycle_Homo sapiens_hsa047211.48583525
30Tryptophan metabolism_Homo sapiens_hsa003801.47215176
31Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.45832622
32Selenocompound metabolism_Homo sapiens_hsa004501.45473222
33Long-term depression_Homo sapiens_hsa047301.42605381
34Protein export_Homo sapiens_hsa030601.41805156
35Cardiac muscle contraction_Homo sapiens_hsa042601.36539137
36Phototransduction_Homo sapiens_hsa047441.36529302
37Dopaminergic synapse_Homo sapiens_hsa047281.33116566
38RNA polymerase_Homo sapiens_hsa030201.28849869
39Fanconi anemia pathway_Homo sapiens_hsa034601.28562868
40RNA degradation_Homo sapiens_hsa030181.27124029
41Vibrio cholerae infection_Homo sapiens_hsa051101.20976715
42Cocaine addiction_Homo sapiens_hsa050301.20266110
43Sphingolipid metabolism_Homo sapiens_hsa006001.19655936
44Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.15555701
45Vitamin B6 metabolism_Homo sapiens_hsa007501.14124210
46Sulfur metabolism_Homo sapiens_hsa009201.12276358
47Linoleic acid metabolism_Homo sapiens_hsa005911.11977301
48Primary bile acid biosynthesis_Homo sapiens_hsa001201.10160395
49SNARE interactions in vesicular transport_Homo sapiens_hsa041301.09999186
50Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.09296624
51Amphetamine addiction_Homo sapiens_hsa050311.08797227
52Cholinergic synapse_Homo sapiens_hsa047251.08660720
53Renin secretion_Homo sapiens_hsa049241.06807447
54Peroxisome_Homo sapiens_hsa041461.06022029
55Salivary secretion_Homo sapiens_hsa049701.05805928
56ABC transporters_Homo sapiens_hsa020101.04585886
57alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.04168257
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04078363
59Taste transduction_Homo sapiens_hsa047421.01481633
60Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.01222746
61Long-term potentiation_Homo sapiens_hsa047201.00940299
62Steroid hormone biosynthesis_Homo sapiens_hsa001400.99626461
63Homologous recombination_Homo sapiens_hsa034400.98056049
64Huntingtons disease_Homo sapiens_hsa050160.95049225
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.94837999
66Renal cell carcinoma_Homo sapiens_hsa052110.94712114
67Gastric acid secretion_Homo sapiens_hsa049710.93626392
68Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.93605467
69Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.93463428
70Circadian rhythm_Homo sapiens_hsa047100.88069611
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.87140735
72Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.86946279
73Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.86333790
74Olfactory transduction_Homo sapiens_hsa047400.86123426
75Chemical carcinogenesis_Homo sapiens_hsa052040.84337379
76Insulin secretion_Homo sapiens_hsa049110.84187309
77Histidine metabolism_Homo sapiens_hsa003400.80910979
78Retinol metabolism_Homo sapiens_hsa008300.80531520
79beta-Alanine metabolism_Homo sapiens_hsa004100.77030824
80Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77026556
81Oxytocin signaling pathway_Homo sapiens_hsa049210.73687251
82Basal cell carcinoma_Homo sapiens_hsa052170.72646321
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.72635209
84Ras signaling pathway_Homo sapiens_hsa040140.68344629
85ErbB signaling pathway_Homo sapiens_hsa040120.66493329
86Calcium signaling pathway_Homo sapiens_hsa040200.65444879
87Gap junction_Homo sapiens_hsa045400.65248137
88Rheumatoid arthritis_Homo sapiens_hsa053230.61009171
89Non-homologous end-joining_Homo sapiens_hsa034500.60816970
90Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60289247
91Fatty acid metabolism_Homo sapiens_hsa012120.59915344
92Glycerolipid metabolism_Homo sapiens_hsa005610.59093707
93Dilated cardiomyopathy_Homo sapiens_hsa054140.58647460
94Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.57433680
95cAMP signaling pathway_Homo sapiens_hsa040240.57298044
96Tight junction_Homo sapiens_hsa045300.57235007
97Propanoate metabolism_Homo sapiens_hsa006400.56203767
98Arachidonic acid metabolism_Homo sapiens_hsa005900.55768599
99Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.55584310
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.54101092
101Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.53825753
102Pancreatic secretion_Homo sapiens_hsa049720.53652428
103cGMP-PKG signaling pathway_Homo sapiens_hsa040220.49698906
104Aldosterone synthesis and secretion_Homo sapiens_hsa049250.49357559
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48681019
106Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.48351020
107Ovarian steroidogenesis_Homo sapiens_hsa049130.45868037
108Endocytosis_Homo sapiens_hsa041440.45749194
109Melanogenesis_Homo sapiens_hsa049160.44785812
110Metabolic pathways_Homo sapiens_hsa011000.42764825
111Phagosome_Homo sapiens_hsa041450.42484340
112Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.42182801
113Hedgehog signaling pathway_Homo sapiens_hsa043400.41405948
114Alcoholism_Homo sapiens_hsa050340.41171129
115One carbon pool by folate_Homo sapiens_hsa006700.40804067
116Choline metabolism in cancer_Homo sapiens_hsa052310.40666886
117Phospholipase D signaling pathway_Homo sapiens_hsa040720.40505861
118Arginine and proline metabolism_Homo sapiens_hsa003300.39890932
119Purine metabolism_Homo sapiens_hsa002300.38827451
120Fatty acid biosynthesis_Homo sapiens_hsa000610.38097896
121MAPK signaling pathway_Homo sapiens_hsa040100.37824395
122Pentose and glucuronate interconversions_Homo sapiens_hsa000400.37646554
123Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.36618544
124Hippo signaling pathway_Homo sapiens_hsa043900.34565214
125Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.34536977
126Fat digestion and absorption_Homo sapiens_hsa049750.33237269
127Intestinal immune network for IgA production_Homo sapiens_hsa046720.33225335
128Ribosome_Homo sapiens_hsa030100.33104053
129Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.32343759
130Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.31887881
131Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30498285
132GnRH signaling pathway_Homo sapiens_hsa049120.30342422
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.30016601
134Lysine degradation_Homo sapiens_hsa003100.29817318
135Dorso-ventral axis formation_Homo sapiens_hsa043200.28973265
136Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.28384474
137Pyruvate metabolism_Homo sapiens_hsa006200.28358702
138Wnt signaling pathway_Homo sapiens_hsa043100.28353935
139Prion diseases_Homo sapiens_hsa050200.28080958
140TGF-beta signaling pathway_Homo sapiens_hsa043500.27872929
141Regulation of autophagy_Homo sapiens_hsa041400.27325208
142Thyroid hormone synthesis_Homo sapiens_hsa049180.26433021

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