ZFP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)6.15151843
2proline metabolic process (GO:0006560)4.69278521
3cell migration in hindbrain (GO:0021535)4.47825502
4neuron cell-cell adhesion (GO:0007158)4.38961370
5transcription from mitochondrial promoter (GO:0006390)4.30033501
6epithelial cilium movement (GO:0003351)4.25461181
7response to pheromone (GO:0019236)4.14801363
8synaptic vesicle exocytosis (GO:0016079)4.10814495
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.10347388
10regulation of respiratory gaseous exchange by neurological system process (GO:0002087)4.03076181
11nucleobase catabolic process (GO:0046113)3.98838140
12behavioral response to nicotine (GO:0035095)3.94571008
13oxidative demethylation (GO:0070989)3.89997751
14establishment of mitochondrion localization (GO:0051654)3.86388473
15gamma-aminobutyric acid transport (GO:0015812)3.83556818
16synaptic vesicle endocytosis (GO:0048488)3.80087886
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.78907619
18replication fork processing (GO:0031297)3.75044057
19negative regulation of synaptic transmission, GABAergic (GO:0032229)3.63400876
20regulation of respiratory system process (GO:0044065)3.62387885
21vocalization behavior (GO:0071625)3.61008517
22regulation of cAMP-dependent protein kinase activity (GO:2000479)3.56490029
23negative regulation of JAK-STAT cascade (GO:0046426)3.55276229
24axoneme assembly (GO:0035082)3.54382189
25presynaptic membrane assembly (GO:0097105)3.53455976
26intraciliary transport (GO:0042073)3.51424903
27postsynaptic membrane organization (GO:0001941)3.49909258
28establishment or maintenance of monopolar cell polarity (GO:0061339)3.49779478
29establishment of monopolar cell polarity (GO:0061162)3.49779478
30regulation of protein homooligomerization (GO:0032462)3.47085278
31mitochondrion transport along microtubule (GO:0047497)3.46535305
32establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.46535305
33cilium morphogenesis (GO:0060271)3.46202660
34cellular ketone body metabolic process (GO:0046950)3.44967625
35pyrimidine nucleobase catabolic process (GO:0006208)3.44538624
36central nervous system projection neuron axonogenesis (GO:0021952)3.43137769
37cilium movement (GO:0003341)3.41944967
38spliceosomal tri-snRNP complex assembly (GO:0000244)3.39774167
39presynaptic membrane organization (GO:0097090)3.39746884
40locomotory exploration behavior (GO:0035641)3.39233854
41positive regulation of protein homooligomerization (GO:0032464)3.38489389
42positive regulation of dendritic spine morphogenesis (GO:0061003)3.35671122
43neuromuscular process controlling posture (GO:0050884)3.35184565
44regulation of glutamate receptor signaling pathway (GO:1900449)3.31897047
45retinal cone cell development (GO:0046549)3.30984681
46regulation of short-term neuronal synaptic plasticity (GO:0048172)3.27672189
47regulation of cilium movement (GO:0003352)3.27286501
48negative regulation of protein oligomerization (GO:0032460)3.25513374
49respiratory chain complex IV assembly (GO:0008535)3.24575378
50aggressive behavior (GO:0002118)3.24123321
51positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.23517826
52regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.23185658
53regulation of synaptic vesicle exocytosis (GO:2000300)3.22071771
54protein polyglutamylation (GO:0018095)3.21531530
55nonmotile primary cilium assembly (GO:0035058)3.21008420
56behavioral response to ethanol (GO:0048149)3.20647217
57protein localization to synapse (GO:0035418)3.19920643
58transmission of nerve impulse (GO:0019226)3.19903913
59mitochondrial fragmentation involved in apoptotic process (GO:0043653)3.19460264
60negative regulation of telomere maintenance (GO:0032205)3.16955089
61protein complex biogenesis (GO:0070271)3.15949398
62auditory receptor cell stereocilium organization (GO:0060088)3.14909712
63spinal cord development (GO:0021510)3.14369955
64preassembly of GPI anchor in ER membrane (GO:0016254)3.14103864
65viral mRNA export from host cell nucleus (GO:0046784)3.14004683
66establishment of protein localization to mitochondrial membrane (GO:0090151)3.12753969
67fucose catabolic process (GO:0019317)3.12695128
68L-fucose metabolic process (GO:0042354)3.12695128
69L-fucose catabolic process (GO:0042355)3.12695128
70neuron recognition (GO:0008038)3.12289304
71convergent extension (GO:0060026)3.11471491
72cullin deneddylation (GO:0010388)3.11314034
73platelet dense granule organization (GO:0060155)3.10570706
74retinal ganglion cell axon guidance (GO:0031290)3.09940804
75cilium organization (GO:0044782)3.09477576
76branched-chain amino acid catabolic process (GO:0009083)3.08816060
77DNA strand renaturation (GO:0000733)3.05816382
78ketone body metabolic process (GO:1902224)3.05796524
79positive regulation of synapse assembly (GO:0051965)3.05224604
80cilium assembly (GO:0042384)3.05130156
81regulation of neuronal synaptic plasticity (GO:0048168)3.03082023
82positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.01903072
83positive regulation of amino acid transport (GO:0051957)3.00970453
84embryonic process involved in female pregnancy (GO:0060136)3.00904102
85regulation of respiratory gaseous exchange (GO:0043576)3.00219301
86cellular response to ATP (GO:0071318)3.00099514
87negative regulation of appetite (GO:0032099)2.98426163
88negative regulation of response to food (GO:0032096)2.98426163
89regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.98048826
90establishment of apical/basal cell polarity (GO:0035089)2.97783131
91neuronal action potential propagation (GO:0019227)2.97533135
92glutamate secretion (GO:0014047)2.97302847
93startle response (GO:0001964)2.96150475
94negative regulation of cytosolic calcium ion concentration (GO:0051481)2.94575088
95neuromuscular process (GO:0050905)2.92307204
96cytochrome complex assembly (GO:0017004)2.91506966
97synaptic vesicle docking involved in exocytosis (GO:0016081)2.91254059
98C4-dicarboxylate transport (GO:0015740)2.91129076
99mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.90375611
100mitochondrial respiratory chain complex I assembly (GO:0032981)2.90375611
101NADH dehydrogenase complex assembly (GO:0010257)2.90375611
102positive regulation of developmental pigmentation (GO:0048087)2.89542507
103limb development (GO:0060173)2.88765615
104appendage development (GO:0048736)2.88765615
105DNA double-strand break processing (GO:0000729)2.88186984
106DNA ligation (GO:0006266)2.87515695
107synaptic vesicle maturation (GO:0016188)2.86941104
108regulation of synaptic vesicle transport (GO:1902803)2.85992993
109neurotransmitter secretion (GO:0007269)2.85398879
110axonal fasciculation (GO:0007413)2.85010473
111cerebellar granule cell differentiation (GO:0021707)2.84323656
112neuromuscular process controlling balance (GO:0050885)2.81979921
113synapse assembly (GO:0007416)2.80790659
114cerebral cortex radially oriented cell migration (GO:0021799)2.80599548
115adult walking behavior (GO:0007628)2.80353029
116protein deneddylation (GO:0000338)2.79287535
117dendrite morphogenesis (GO:0048813)2.78921535
118protein-cofactor linkage (GO:0018065)2.78362871
119mitochondrial respiratory chain complex assembly (GO:0033108)2.77122407
120olfactory bulb development (GO:0021772)2.75411541
121establishment of synaptic vesicle localization (GO:0097480)2.75126239
122synaptic vesicle transport (GO:0048489)2.75126239
123DNA integration (GO:0015074)2.75080007
124lateral sprouting from an epithelium (GO:0060601)2.74574878
125regulation of acyl-CoA biosynthetic process (GO:0050812)2.74504053
126inner ear receptor stereocilium organization (GO:0060122)2.74442436
127dendritic spine morphogenesis (GO:0060997)2.73337293
128kidney morphogenesis (GO:0060993)2.73013327
129negative regulation of heart rate (GO:0010459)2.72731985
130seminiferous tubule development (GO:0072520)2.72289907
131negative regulation of transcription regulatory region DNA binding (GO:2000678)2.72119898
132negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.71758579
133mannosylation (GO:0097502)2.71268597
134mechanosensory behavior (GO:0007638)2.70999011
135regulation of glucokinase activity (GO:0033131)2.70794912
136regulation of hexokinase activity (GO:1903299)2.70794912
137protein targeting to vacuole (GO:0006623)2.70745746
138protein targeting to lysosome (GO:0006622)2.70745746
139establishment of protein localization to vacuole (GO:0072666)2.70745746
140exploration behavior (GO:0035640)2.70133992
141synaptic transmission, glutamatergic (GO:0035249)2.70078481
142synapsis (GO:0007129)2.69932896
143single strand break repair (GO:0000012)2.69642005
144negative regulation of Ras GTPase activity (GO:0034261)2.68979021
145maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.68587087
146somatic hypermutation of immunoglobulin genes (GO:0016446)2.67371914
147somatic diversification of immune receptors via somatic mutation (GO:0002566)2.67371914
148protein localization to cilium (GO:0061512)2.67330843
149positive regulation of synaptic transmission, GABAergic (GO:0032230)2.67324662
150neuron-neuron synaptic transmission (GO:0007270)2.66623399
151G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.66513916
152regulation of long-term neuronal synaptic plasticity (GO:0048169)2.65775008
153regulation of glycogen (starch) synthase activity (GO:2000465)2.65756313
154regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.65535345
155ubiquinone metabolic process (GO:0006743)2.64329316
156somite rostral/caudal axis specification (GO:0032525)2.63525771
157cornea development in camera-type eye (GO:0061303)2.63455001
158positive regulation of mitochondrial fission (GO:0090141)2.63452064
159head development (GO:0060322)2.62942967
160nephron tubule morphogenesis (GO:0072078)2.62732794
161nephron epithelium morphogenesis (GO:0072088)2.62732794
162negative regulation of neurotransmitter transport (GO:0051589)2.62514465
163axon ensheathment in central nervous system (GO:0032291)2.62470245
164photoreceptor cell development (GO:0042461)2.59835472
165ubiquinone biosynthetic process (GO:0006744)2.59696762
166cholesterol biosynthetic process (GO:0006695)2.57644767
167neural tube formation (GO:0001841)2.56507964
168somite development (GO:0061053)2.54433617
169regulation of non-canonical Wnt signaling pathway (GO:2000050)2.54169461
170photoreceptor cell maintenance (GO:0045494)2.53429408
171aldehyde catabolic process (GO:0046185)2.52097799
172detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.51770934
173auditory behavior (GO:0031223)2.50446079
174calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.48892880
175regulation of telomere maintenance (GO:0032204)2.46787950
176smoothened signaling pathway (GO:0007224)2.46420157
177neuronal action potential (GO:0019228)2.45206824
178limb bud formation (GO:0060174)2.45069718
179regulation of sulfur metabolic process (GO:0042762)2.44957136
180regulation of cofactor metabolic process (GO:0051193)2.44406007
181regulation of coenzyme metabolic process (GO:0051196)2.44406007
182regulation of microtubule-based movement (GO:0060632)2.44323702
183protein neddylation (GO:0045116)2.44255736
184eye photoreceptor cell development (GO:0042462)2.44184048
185glycerophospholipid catabolic process (GO:0046475)2.44084860
186branched-chain amino acid metabolic process (GO:0009081)2.43917562
187anterograde synaptic vesicle transport (GO:0048490)2.42906915

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.08769403
2* ZNF274_21170338_ChIP-Seq_K562_Hela3.96348302
3GBX2_23144817_ChIP-Seq_PC3_Human3.37070612
4IGF1R_20145208_ChIP-Seq_DFB_Human2.88025050
5ERG_21242973_ChIP-ChIP_JURKAT_Human2.67202805
6RBPJ_22232070_ChIP-Seq_NCS_Mouse2.66150021
7ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.61432750
8POU3F2_20337985_ChIP-ChIP_501MEL_Human2.50347243
9* REST_21632747_ChIP-Seq_MESCs_Mouse2.50206701
10SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.37198174
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.35833860
12TAF15_26573619_Chip-Seq_HEK293_Human2.35464448
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.35275195
14SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.29297797
15GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.23324088
16FLI1_27457419_Chip-Seq_LIVER_Mouse2.22362890
17EZH2_27304074_Chip-Seq_ESCs_Mouse2.20454141
18JARID2_20064375_ChIP-Seq_MESCs_Mouse2.14294830
19* REST_18959480_ChIP-ChIP_MESCs_Mouse2.13685061
20SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.11767300
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.10736310
22JARID2_20075857_ChIP-Seq_MESCs_Mouse2.10606185
23SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.09960568
24EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.04145128
25EWS_26573619_Chip-Seq_HEK293_Human1.97483260
26P300_19829295_ChIP-Seq_ESCs_Human1.96210362
27RARB_27405468_Chip-Seq_BRAIN_Mouse1.95298290
28CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.92158725
29RNF2_18974828_ChIP-Seq_MESCs_Mouse1.90319684
30EZH2_18974828_ChIP-Seq_MESCs_Mouse1.90319684
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.85398892
32PCGF2_27294783_Chip-Seq_ESCs_Mouse1.83547882
33SUZ12_27294783_Chip-Seq_ESCs_Mouse1.81679373
34SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.81348853
35GABP_17652178_ChIP-ChIP_JURKAT_Human1.81125543
36RING1B_27294783_Chip-Seq_NPCs_Mouse1.80401778
37KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.79237884
38AR_21572438_ChIP-Seq_LNCaP_Human1.78795803
39SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.78346904
40RNF2_27304074_Chip-Seq_ESCs_Mouse1.76409511
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.75754174
42EED_16625203_ChIP-ChIP_MESCs_Mouse1.75197266
43NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.75096555
44VDR_22108803_ChIP-Seq_LS180_Human1.72569989
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.70241524
46TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.70119491
47PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.69772336
48CBP_20019798_ChIP-Seq_JUKART_Human1.69499671
49IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.69499671
50ZFP281_18757296_ChIP-ChIP_E14_Mouse1.68715156
51* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.68016645
52POU5F1_16518401_ChIP-PET_MESCs_Mouse1.66568920
53SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.65836698
54RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.65783424
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.65636107
56SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.65054735
57SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.64651473
58MTF2_20144788_ChIP-Seq_MESCs_Mouse1.63771599
59CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.60521685
60PCGF2_27294783_Chip-Seq_NPCs_Mouse1.60505136
61AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.58987578
62EZH2_27294783_Chip-Seq_ESCs_Mouse1.58521036
63SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.57163202
64HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.55305894
65KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.53269680
66KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.53269680
67KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.53269680
68CTBP1_25329375_ChIP-Seq_LNCAP_Human1.53004470
69AR_25329375_ChIP-Seq_VCAP_Human1.52553365
70RNF2_27304074_Chip-Seq_NSC_Mouse1.52487967
71PIAS1_25552417_ChIP-Seq_VCAP_Human1.52249561
72SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.51882482
73DROSHA_22980978_ChIP-Seq_HELA_Human1.51510001
74ER_23166858_ChIP-Seq_MCF-7_Human1.50824545
75SMAD4_21799915_ChIP-Seq_A2780_Human1.49358075
76ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.49102961
77EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.48562551
78NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.46994642
79POU5F1_16153702_ChIP-ChIP_HESCs_Human1.46265432
80TCF3_18692474_ChIP-Seq_MESCs_Mouse1.45463659
81SUZ12_27294783_Chip-Seq_NPCs_Mouse1.44145445
82STAT3_23295773_ChIP-Seq_U87_Human1.42487108
83TP53_20018659_ChIP-ChIP_R1E_Mouse1.40796095
84TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38408019
85BCAT_22108803_ChIP-Seq_LS180_Human1.38353516
86MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.37812951
87THAP11_20581084_ChIP-Seq_MESCs_Mouse1.37489947
88SALL1_21062744_ChIP-ChIP_HESCs_Human1.36583043
89UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.36551506
90PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.34493786
91EST1_17652178_ChIP-ChIP_JURKAT_Human1.34105009
92TP53_22573176_ChIP-Seq_HFKS_Human1.33764265
93TCF4_22108803_ChIP-Seq_LS180_Human1.33085506
94MYC_18940864_ChIP-ChIP_HL60_Human1.33062191
95P53_22127205_ChIP-Seq_FIBROBLAST_Human1.32251306
96* TCF4_23295773_ChIP-Seq_U87_Human1.29205242
97STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.28321588
98NR3C1_21868756_ChIP-Seq_MCF10A_Human1.27730121
99NFE2_27457419_Chip-Seq_LIVER_Mouse1.27654494
100RING1B_27294783_Chip-Seq_ESCs_Mouse1.27164882
101KLF5_20875108_ChIP-Seq_MESCs_Mouse1.27108007
102ELK1_19687146_ChIP-ChIP_HELA_Human1.25825392
103EZH2_27294783_Chip-Seq_NPCs_Mouse1.25583191
104GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.24873182
105* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.24568190
106E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.23522020
107CTBP2_25329375_ChIP-Seq_LNCAP_Human1.22421758
108SOX2_19829295_ChIP-Seq_ESCs_Human1.22074494
109NANOG_19829295_ChIP-Seq_ESCs_Human1.22074494
110NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.21443180
111TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.20006304
112RUNX2_22187159_ChIP-Seq_PCA_Human1.19696733
113NANOG_18555785_Chip-Seq_ESCs_Mouse1.18798764
114RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16916065
115ZFP57_27257070_Chip-Seq_ESCs_Mouse1.16568095
116EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15694218
117ZFP281_27345836_Chip-Seq_ESCs_Mouse1.15011619
118ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.12649923
119ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.11890062
120RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09180435
121SOX2_18555785_ChIP-Seq_MESCs_Mouse1.08538908
122POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.08529418
123FOXA1_25329375_ChIP-Seq_VCAP_Human1.08462878
124FOXA1_27270436_Chip-Seq_PROSTATE_Human1.08462878
125NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.07894640
126PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.06747997
127KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.05471384
128TBX3_20139965_ChIP-Seq_MESCs_Mouse1.05236188
129IRF1_19129219_ChIP-ChIP_H3396_Human1.05095716
130TBX3_20139965_ChIP-Seq_ESCs_Mouse1.04770226
131SMAD4_21741376_ChIP-Seq_EPCs_Human1.04738807
132NANOG_21062744_ChIP-ChIP_HESCs_Human1.04111014
133SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03985474
134TAL1_26923725_Chip-Seq_HPCs_Mouse1.03830161
135P53_22387025_ChIP-Seq_ESCs_Mouse1.03770816
136VDR_23849224_ChIP-Seq_CD4+_Human1.02912175
137TP63_19390658_ChIP-ChIP_HaCaT_Human1.01829902
138TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00815772
139CRX_20693478_ChIP-Seq_RETINA_Mouse1.00749950
140NCOR_22424771_ChIP-Seq_293T_Human1.00738094
141MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00304065
142FUS_26573619_Chip-Seq_HEK293_Human0.99769646
143ESR1_15608294_ChIP-ChIP_MCF-7_Human0.99751623
144FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.99351980
145SRF_21415370_ChIP-Seq_HL-1_Mouse0.99026187
146TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97842168
147PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.97709268
148SMAD3_21741376_ChIP-Seq_EPCs_Human0.96078308
149SUZ12_18555785_Chip-Seq_ESCs_Mouse0.95733543
150HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.95136073
151CTCF_27219007_Chip-Seq_Bcells_Human0.94872165
152FOXA1_21572438_ChIP-Seq_LNCaP_Human0.94706518
153TET1_21490601_ChIP-Seq_MESCs_Mouse0.94588011
154PRDM14_20953172_ChIP-Seq_ESCs_Human0.94554160
155FLI1_21867929_ChIP-Seq_TH2_Mouse0.94045203
156DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.93237272
157TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.92332969
158AR_19668381_ChIP-Seq_PC3_Human0.92065679
159* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.91406289
160SOX9_26525672_Chip-Seq_HEART_Mouse0.90803917
161SOX2_21211035_ChIP-Seq_LN229_Gbm0.89694273
162TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.89119974
163POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.89119974
164HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.88918727
165OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.88476185
166DNAJC2_21179169_ChIP-ChIP_NT2_Human0.88218760
167YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88117651
168IKZF1_21737484_ChIP-ChIP_HCT116_Human0.87846140
169NANOG_18692474_ChIP-Seq_MESCs_Mouse0.87561292
170SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.87020526

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.58678299
2MP0005171_absent_coat_pigmentation3.57543243
3MP0003880_abnormal_central_pattern3.32674450
4MP0003635_abnormal_synaptic_transmissio2.71815569
5MP0009046_muscle_twitch2.59483219
6MP0002063_abnormal_learning/memory/cond2.54531630
7MP0002572_abnormal_emotion/affect_behav2.43460459
8MP0000778_abnormal_nervous_system2.43100619
9MP0004270_analgesia2.42682151
10MP0002064_seizures2.40001958
11MP0002638_abnormal_pupillary_reflex2.39661689
12MP0006072_abnormal_retinal_apoptosis2.34909856
13MP0003195_calcinosis2.34774294
14MP0008057_abnormal_DNA_replication2.23551162
15MP0001968_abnormal_touch/_nociception2.21153644
16MP0005646_abnormal_pituitary_gland2.18415676
17MP0009745_abnormal_behavioral_response2.14521285
18MP0002102_abnormal_ear_morphology2.13298788
19MP0010030_abnormal_orbit_morphology2.11474825
20MP0004233_abnormal_muscle_weight2.07671788
21MP0002272_abnormal_nervous_system2.06151956
22MP0005645_abnormal_hypothalamus_physiol2.02198820
23MP0004142_abnormal_muscle_tone1.98644890
24MP0003890_abnormal_embryonic-extraembry1.95243354
25MP0001986_abnormal_taste_sensitivity1.93438908
26MP0002736_abnormal_nociception_after1.93232534
27MP0002184_abnormal_innervation1.89974041
28MP0002734_abnormal_mechanical_nocicepti1.89590106
29MP0005423_abnormal_somatic_nervous1.89386896
30MP0004133_heterotaxia1.89283556
31MP0003121_genomic_imprinting1.86854986
32MP0001486_abnormal_startle_reflex1.86380518
33MP0001529_abnormal_vocalization1.85945055
34MP0004147_increased_porphyrin_level1.84712534
35MP0002163_abnormal_gland_morphology1.82632775
36MP0002733_abnormal_thermal_nociception1.78028918
37MP0000955_abnormal_spinal_cord1.75535711
38MP0001970_abnormal_pain_threshold1.73881987
39MP0008789_abnormal_olfactory_epithelium1.73343201
40MP0002067_abnormal_sensory_capabilities1.72265154
41MP0002837_dystrophic_cardiac_calcinosis1.71313406
42MP0000372_irregular_coat_pigmentation1.69097542
43MP0005394_taste/olfaction_phenotype1.67106881
44MP0005499_abnormal_olfactory_system1.67106881
45MP0002234_abnormal_pharynx_morphology1.60046134
46MP0003136_yellow_coat_color1.59159161
47MP0003119_abnormal_digestive_system1.58032292
48MP0004811_abnormal_neuron_physiology1.57132023
49MP0001984_abnormal_olfaction1.55439344
50MP0002653_abnormal_ependyma_morphology1.54755200
51MP0003011_delayed_dark_adaptation1.53421454
52MP0002882_abnormal_neuron_morphology1.51817207
53MP0002735_abnormal_chemical_nociception1.48527253
54MP0008875_abnormal_xenobiotic_pharmacok1.44959317
55MP0004924_abnormal_behavior1.44947672
56MP0005386_behavior/neurological_phenoty1.44947672
57MP0005084_abnormal_gallbladder_morpholo1.42657253
58MP0001293_anophthalmia1.41008024
59MP0003283_abnormal_digestive_organ1.40706078
60MP0003123_paternal_imprinting1.40255371
61MP0005248_abnormal_Harderian_gland1.40182307
62MP0001188_hyperpigmentation1.34713671
63MP0002557_abnormal_social/conspecific_i1.34684778
64MP0000631_abnormal_neuroendocrine_gland1.34659021
65MP0002066_abnormal_motor_capabilities/c1.34618529
66MP0004885_abnormal_endolymph1.33826039
67MP0002160_abnormal_reproductive_system1.33468099
68MP0002249_abnormal_larynx_morphology1.32511720
69MP0002152_abnormal_brain_morphology1.31558257
70MP0000427_abnormal_hair_cycle1.30036315
71MP0006276_abnormal_autonomic_nervous1.29477676
72MP0008569_lethality_at_weaning1.28447680
73MP0005551_abnormal_eye_electrophysiolog1.27592672
74MP0003646_muscle_fatigue1.27479083
75MP0000516_abnormal_urinary_system1.27300395
76MP0005367_renal/urinary_system_phenotyp1.27300395
77MP0001485_abnormal_pinna_reflex1.26222315
78MP0008872_abnormal_physiological_respon1.26125974
79MP0006292_abnormal_olfactory_placode1.25474978
80MP0001440_abnormal_grooming_behavior1.23553076
81MP0003137_abnormal_impulse_conducting1.22924465
82MP0002751_abnormal_autonomic_nervous1.21448954
83MP0005253_abnormal_eye_physiology1.18966675
84MP0002009_preneoplasia1.18901164
85MP0000462_abnormal_digestive_system1.18263458
86MP0003122_maternal_imprinting1.17211755
87MP0002752_abnormal_somatic_nervous1.16250627
88MP0006054_spinal_hemorrhage1.16214856
89MP0004742_abnormal_vestibular_system1.14265467
90MP0001502_abnormal_circadian_rhythm1.13249149
91MP0000049_abnormal_middle_ear1.12167138
92MP0005379_endocrine/exocrine_gland_phen1.11789136
93MP0002876_abnormal_thyroid_physiology1.09932851
94MP0003861_abnormal_nervous_system1.09654545
95MP0002822_catalepsy1.09070215
96MP0001764_abnormal_homeostasis1.08151751
97MP0002282_abnormal_trachea_morphology1.07804267
98MP0000647_abnormal_sebaceous_gland1.06053043
99MP0003634_abnormal_glial_cell1.04614879
100MP0001963_abnormal_hearing_physiology1.03119953
101MP0002233_abnormal_nose_morphology1.02709815
102MP0003938_abnormal_ear_development1.02236990
103MP0008058_abnormal_DNA_repair1.01553746
104MP0003633_abnormal_nervous_system1.01189294
105MP0000026_abnormal_inner_ear1.01062752
106MP0001905_abnormal_dopamine_level1.00790099
107MP0003937_abnormal_limbs/digits/tail_de0.97204732
108MP0005391_vision/eye_phenotype0.96138519
109MP0002909_abnormal_adrenal_gland0.95985034
110MP0005187_abnormal_penis_morphology0.95374442
111MP0008877_abnormal_DNA_methylation0.95111968
112MP0002090_abnormal_vision0.94555488
113MP0005389_reproductive_system_phenotype0.94526410
114MP0003718_maternal_effect0.94437905
115MP0002928_abnormal_bile_duct0.94060752
116MP0003631_nervous_system_phenotype0.93476400
117MP0009780_abnormal_chondrocyte_physiolo0.92631011
118MP0001340_abnormal_eyelid_morphology0.91051561
119MP0002229_neurodegeneration0.89939390
120MP0003172_abnormal_lysosome_physiology0.89050392
121MP0008995_early_reproductive_senescence0.88606153
122MP0002108_abnormal_muscle_morphology0.88487167
123MP0000015_abnormal_ear_pigmentation0.87007431
124MP0001943_abnormal_respiration0.85683068
125MP0002138_abnormal_hepatobiliary_system0.85427238
126MP0004858_abnormal_nervous_system0.84956141
127MP0005174_abnormal_tail_pigmentation0.83634566
128MP0003755_abnormal_palate_morphology0.82792249
129MP0005195_abnormal_posterior_eye0.82178766
130MP0004134_abnormal_chest_morphology0.82067565
131MP0003787_abnormal_imprinting0.80846579
132MP0002938_white_spotting0.78985427
133MP0003385_abnormal_body_wall0.78136371
134MP0002116_abnormal_craniofacial_bone0.77546652
135MP0000639_abnormal_adrenal_gland0.77159799
136MP0004145_abnormal_muscle_electrophysio0.75390004
137MP0010770_preweaning_lethality0.74996708
138MP0002082_postnatal_lethality0.74996708
139MP0009278_abnormal_bone_marrow0.73681227
140MP0010768_mortality/aging0.72596397
141MP0010769_abnormal_survival0.72586683
142MP0001501_abnormal_sleep_pattern0.71937108
143MP0002114_abnormal_axial_skeleton0.71788661

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic fibrosis (HP:0100732)4.74011275
2True hermaphroditism (HP:0010459)4.45989479
3Myokymia (HP:0002411)4.36835027
4Pancreatic cysts (HP:0001737)4.31780807
5Molar tooth sign on MRI (HP:0002419)4.18235623
6Abnormality of midbrain morphology (HP:0002418)4.18235623
7Focal motor seizures (HP:0011153)4.07140722
8Alacrima (HP:0000522)3.70000281
9Atonic seizures (HP:0010819)3.65971130
10Annular pancreas (HP:0001734)3.59127884
11Nephronophthisis (HP:0000090)3.53769493
12Epileptic encephalopathy (HP:0200134)3.48261346
13Febrile seizures (HP:0002373)3.33694514
14Abnormality of the labia minora (HP:0012880)3.33550277
15Anteriorly placed anus (HP:0001545)3.33084066
16Intestinal atresia (HP:0011100)3.30630580
17Concave nail (HP:0001598)3.28149727
18Rectal fistula (HP:0100590)3.21606625
19Rectovaginal fistula (HP:0000143)3.21606625
20Coronal craniosynostosis (HP:0004440)3.11488640
21Gait imbalance (HP:0002141)3.09642169
22Turricephaly (HP:0000262)3.02834702
23Facial hemangioma (HP:0000329)3.00740670
24Focal seizures (HP:0007359)2.98456024
25Decreased lacrimation (HP:0000633)2.97530655
26Cystic liver disease (HP:0006706)2.96656298
27Hyperinsulinemic hypoglycemia (HP:0000825)2.91905677
28Rib fusion (HP:0000902)2.86847786
29Absence seizures (HP:0002121)2.86422231
30Narrow nasal bridge (HP:0000446)2.85844530
31Bile duct proliferation (HP:0001408)2.82824804
32Abnormal biliary tract physiology (HP:0012439)2.82824804
33Abnormality of the renal medulla (HP:0100957)2.81485963
34Pheochromocytoma (HP:0002666)2.78671015
35Intestinal fistula (HP:0100819)2.77687758
36Clumsiness (HP:0002312)2.76521508
37Abolished electroretinogram (ERG) (HP:0000550)2.76200890
38Congenital primary aphakia (HP:0007707)2.75835581
39Hyperventilation (HP:0002883)2.65183657
40Aplasia/Hypoplasia of the tongue (HP:0010295)2.61785073
41Vaginal fistula (HP:0004320)2.60496018
42Hepatic necrosis (HP:0002605)2.59956602
43Dialeptic seizures (HP:0011146)2.57821794
44Chronic hepatic failure (HP:0100626)2.57399156
45Postaxial foot polydactyly (HP:0001830)2.55897600
46Specific learning disability (HP:0001328)2.55715158
47Hypochromic microcytic anemia (HP:0004840)2.55341868
48Poor suck (HP:0002033)2.52012247
49Nephrogenic diabetes insipidus (HP:0009806)2.51160003
50Fetal akinesia sequence (HP:0001989)2.50352381
51Acute encephalopathy (HP:0006846)2.49927677
52Medial flaring of the eyebrow (HP:0010747)2.48923226
53Congenital hepatic fibrosis (HP:0002612)2.48514038
54Congenital stationary night blindness (HP:0007642)2.47355781
55Progressive cerebellar ataxia (HP:0002073)2.47050632
56Postaxial hand polydactyly (HP:0001162)2.42655445
57Hepatocellular necrosis (HP:0001404)2.40873879
58Neuroendocrine neoplasm (HP:0100634)2.40680542
59Abnormality of the aortic arch (HP:0012303)2.40130553
60Increased IgM level (HP:0003496)2.40027366
61Broad-based gait (HP:0002136)2.37928694
62Hyperglycinemia (HP:0002154)2.37694320
63Failure to thrive in infancy (HP:0001531)2.37514016
64Dysdiadochokinesis (HP:0002075)2.36700526
65Anencephaly (HP:0002323)2.35784931
66Thickened helices (HP:0000391)2.34409614
67Pendular nystagmus (HP:0012043)2.33036441
68Hypoglycemic coma (HP:0001325)2.32966698
69Bifid tongue (HP:0010297)2.32474701
70Hemiparesis (HP:0001269)2.30977123
71Narrow forehead (HP:0000341)2.30209606
72Abnormality of the renal cortex (HP:0011035)2.29909149
73Sclerocornea (HP:0000647)2.29369015
74Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.28672234
75Genital tract atresia (HP:0001827)2.28344910
76Acute necrotizing encephalopathy (HP:0006965)2.27915414
773-Methylglutaconic aciduria (HP:0003535)2.26364281
78Vaginal atresia (HP:0000148)2.24333240
79Occipital encephalocele (HP:0002085)2.23890066
80Attenuation of retinal blood vessels (HP:0007843)2.23416668
81Diminished movement (HP:0002374)2.23184644
82Mitochondrial inheritance (HP:0001427)2.22664852
83Visual hallucinations (HP:0002367)2.22612773
84Progressive macrocephaly (HP:0004481)2.21996270
85Colon cancer (HP:0003003)2.21657295
86Epileptiform EEG discharges (HP:0011182)2.20160283
87Supernumerary spleens (HP:0009799)2.20100368
88Hypoglycemic seizures (HP:0002173)2.19907465
89Ankle clonus (HP:0011448)2.19463224
90Akinesia (HP:0002304)2.18477095
91Male pseudohermaphroditism (HP:0000037)2.18132428
92Orthostatic hypotension (HP:0001278)2.17419039
93Abnormal drinking behavior (HP:0030082)2.17268935
94Polydipsia (HP:0001959)2.17268935
95Tongue fasciculations (HP:0001308)2.14449555
96EEG with generalized epileptiform discharges (HP:0011198)2.13604940
97Preaxial hand polydactyly (HP:0001177)2.13415844
98Hypsarrhythmia (HP:0002521)2.12684455
99Increased CSF lactate (HP:0002490)2.12650223
100Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.12425599
101Male infertility (HP:0003251)2.11858634
102Choanal stenosis (HP:0000452)2.11705964
103Tachypnea (HP:0002789)2.11639010
104Broad alveolar ridges (HP:0000187)2.11047401
105Short chin (HP:0000331)2.09129141
106Growth hormone deficiency (HP:0000824)2.08415126
107Gonadotropin excess (HP:0000837)2.06638757
108Limb dystonia (HP:0002451)2.06401354
109Gastrointestinal atresia (HP:0002589)2.06067027
110Hypothermia (HP:0002045)2.05780323
111Abnormality of the lower motor neuron (HP:0002366)2.05016437
112Abnormal rod and cone electroretinograms (HP:0008323)2.04649860
113Renal cortical cysts (HP:0000803)2.04459214
114Poor coordination (HP:0002370)2.03875641
115Abnormality of the parathyroid morphology (HP:0011766)2.02952010
116Action tremor (HP:0002345)2.02610338
117Oculomotor apraxia (HP:0000657)2.02163268
118Hamartoma (HP:0010566)2.01347259
119Short humerus (HP:0005792)2.01046664
120Cerebellar dysplasia (HP:0007033)2.00752449
121Increased hepatocellular lipid droplets (HP:0006565)1.98897207
122Abnormality of macular pigmentation (HP:0008002)1.98078980
123Sleep apnea (HP:0010535)1.98013901
124Neoplasm of the adrenal cortex (HP:0100641)1.96702131
125Oligodactyly (hands) (HP:0001180)1.95780216
126Intention tremor (HP:0002080)1.95093691
127Drooling (HP:0002307)1.95038320
128Neoplasm of the peripheral nervous system (HP:0100007)1.94887078
129Dysmetria (HP:0001310)1.94821892
130Aplasia/hypoplasia of the humerus (HP:0006507)1.94629572
131Degeneration of the lateral corticospinal tracts (HP:0002314)1.94500747
132Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.94500747
133Abnormal mitochondria in muscle tissue (HP:0008316)1.94180861
134Aplasia/Hypoplasia of the tibia (HP:0005772)1.94050322
135Septo-optic dysplasia (HP:0100842)1.93967344
136Obstructive sleep apnea (HP:0002870)1.93450445
137Optic nerve hypoplasia (HP:0000609)1.93006654
138Lipid accumulation in hepatocytes (HP:0006561)1.92074567
139Anophthalmia (HP:0000528)1.91365671
140Bony spicule pigmentary retinopathy (HP:0007737)1.91046407
141Impaired vibration sensation in the lower limbs (HP:0002166)1.88651883
142Choroideremia (HP:0001139)1.88476435
143Astrocytoma (HP:0009592)1.88432127
144Abnormality of the astrocytes (HP:0100707)1.88432127
145Median cleft lip (HP:0000161)1.88353763
146Furrowed tongue (HP:0000221)1.86385707
147Abnormality of the corticospinal tract (HP:0002492)1.86369865
148Generalized tonic-clonic seizures (HP:0002069)1.85544459
149Congenital hip dislocation (HP:0001374)1.84574263
150Large for gestational age (HP:0001520)1.84409695
151Aplasia/Hypoplasia of the spleen (HP:0010451)1.83526048
152Cerebral hypomyelination (HP:0006808)1.82883437
153Aganglionic megacolon (HP:0002251)1.82875222
154Abnormality of the metopic suture (HP:0005556)1.82622380
155Tubular atrophy (HP:0000092)1.82469628
156Gastroesophageal reflux (HP:0002020)1.82120172
157Esotropia (HP:0000565)1.81952148
158Bulbar palsy (HP:0001283)1.81934586
159Dandy-Walker malformation (HP:0001305)1.81505980
160Dysautonomia (HP:0002459)1.80441423
161Thyroiditis (HP:0100646)1.79723985
162Ulnar claw (HP:0001178)1.79553867
163Muscle fibrillation (HP:0010546)1.79498753
164Polyphagia (HP:0002591)1.79431358
165Split foot (HP:0001839)1.78950087
166Pachygyria (HP:0001302)1.78850052
167Short foot (HP:0001773)1.77740751
168Tubulointerstitial nephritis (HP:0001970)1.77592855
169Optic disc pallor (HP:0000543)1.76741627
170Type II lissencephaly (HP:0007260)1.76731283
171Aplasia involving forearm bones (HP:0009822)1.76588615
172Absent forearm bone (HP:0003953)1.76588615
173Absent radius (HP:0003974)1.76445458
174Hyperglycinuria (HP:0003108)1.75071200
175Ectopic anus (HP:0004397)1.74790996
176Increased corneal curvature (HP:0100692)1.74361210
177Keratoconus (HP:0000563)1.74361210
178Short tibia (HP:0005736)1.74334796
179Symptomatic seizures (HP:0011145)1.73966932
180Absent speech (HP:0001344)1.73155581

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK4.91158640
2FRK4.02124986
3MAPK153.53266186
4CASK3.38869232
5UHMK13.02528778
6MAP3K62.96751444
7DDR22.95287839
8NUAK12.71368649
9PINK12.67624944
10TYRO32.60427583
11MARK12.54443047
12DAPK12.33957759
13NTRK32.27424203
14FGR2.22671236
15MAP4K22.21387152
16YES12.06961713
17ZAK1.94987807
18GRK11.90850029
19PHKG21.88829297
20PHKG11.88829297
21NTRK21.84880845
22PRPF4B1.74094764
23MAP3K91.72626247
24MATK1.72377105
25MAP3K41.69878166
26AKT31.68675788
27TRIM281.67331859
28WNK41.63485150
29DYRK21.53384212
30MAP2K71.46403761
31TNIK1.40997377
32BCKDK1.40849696
33PAK31.39606820
34MST41.36584751
35CSNK1A1L1.33031711
36MINK11.32238402
37EPHA41.29065922
38TAOK31.28966247
39ERBB31.27207981
40MAP3K111.26165512
41LATS21.25516961
42NLK1.24033133
43FLT31.22098546
44CDK191.19997628
45WNK31.15587814
46PDGFRA1.15260682
47PRKD31.14453002
48PLK31.12845287
49PRKD21.11470259
50DYRK31.09317381
51MAPK131.09262343
52CAMK2B1.08072623
53VRK21.07401198
54OXSR11.05865079
55PBK1.05788273
56CDK51.01496957
57STK161.00694902
58VRK10.99201550
59ACVR1B0.97648292
60INSRR0.97498546
61DYRK1B0.97182502
62PKN20.96384549
63PAK60.95860826
64CAMK2A0.92479278
65CAMKK20.91967554
66MKNK10.91685355
67BCR0.89163339
68TSSK60.88065099
69BRSK20.85533916
70CDC42BPA0.84266619
71DAPK20.84151647
72CDK180.78770506
73CDK70.77027393
74PIM20.76854462
75CDK150.76405506
76MAP3K120.76340885
77CAMK2G0.75968399
78BMX0.75463056
79TLK10.75237399
80SRPK10.74240573
81SGK4940.73809818
82SGK2230.73809818
83BRD40.72180265
84CDK140.69193379
85GSK3A0.67947554
86CDK11A0.67853125
87RPS6KC10.67000143
88RPS6KL10.67000143
89PRKCG0.66843498
90STK38L0.63979426
91STK30.63126953
92CSK0.61588794
93BMPR1B0.60534546
94PLK40.60471193
95PKN10.60292757
96CAMK2D0.59730874
97MAP2K40.58807116
98KSR10.58571996
99OBSCN0.58187995
100NEK10.58137393
101EIF2AK30.57185774
102STK390.55826282
103FER0.55117973
104TIE10.54490082
105CSNK1G20.54199071
106SGK10.53803970
107CDK80.53597582
108RPS6KB10.52879705
109TXK0.52512404
110LIMK10.50702237
111RPS6KA60.50137660
112PRKCZ0.47625090
113CDC70.47353942
114GRK50.47267523
115CDK30.47210170
116HIPK20.46450540
117TNK20.45678303
118PRKAA10.45543359
119CSNK1A10.44414388
120MAPK100.43891594
121MUSK0.43631463
122EIF2AK10.43208138
123PLK10.42666296
124PDK20.42402399
125CSNK1G10.41911775
126MAPKAPK50.41826192
127NTRK10.40636277
128DYRK1A0.39664271
129PRKCQ0.39505615
130CSNK1G30.38457349
131RPS6KA30.38186684
132CAMK10.38109089
133TGFBR10.37990057
134PRKCE0.37790105
135ATM0.36445797
136FGFR20.36405742
137ADRBK20.35643611
138PRKCI0.35372521
139RPS6KA10.35351746
140PTK2B0.34672103
141STK110.34433722
142PLK20.34118838
143SIK30.34030749
144EPHB20.32800842
145SGK20.32725711
146MKNK20.31952045
147PRKACA0.31912510
148ERBB40.31535422
149BUB10.30784642
150CHEK20.30737733
151GSK3B0.29460894
152ROCK20.28162223
153ADRBK10.27777092
154PNCK0.27704433
155MARK20.26740438

Predicted pathways (KEGG)

RankGene SetZ-score
1Taurine and hypotaurine metabolism_Homo sapiens_hsa004304.06451078
2Nicotine addiction_Homo sapiens_hsa050333.40100888
3Fatty acid biosynthesis_Homo sapiens_hsa000613.18045378
4Synaptic vesicle cycle_Homo sapiens_hsa047212.79364645
5Propanoate metabolism_Homo sapiens_hsa006402.58633543
6GABAergic synapse_Homo sapiens_hsa047272.58531180
7Protein export_Homo sapiens_hsa030602.45246778
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.39989176
9Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.19555643
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.12477366
11Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.04987849
12Morphine addiction_Homo sapiens_hsa050322.04108293
13Olfactory transduction_Homo sapiens_hsa047402.03082623
14Glutamatergic synapse_Homo sapiens_hsa047241.97234454
15Nitrogen metabolism_Homo sapiens_hsa009101.90782182
16Dopaminergic synapse_Homo sapiens_hsa047281.89975451
17Circadian rhythm_Homo sapiens_hsa047101.81585539
18Circadian entrainment_Homo sapiens_hsa047131.79980025
19Hedgehog signaling pathway_Homo sapiens_hsa043401.77049258
20Amphetamine addiction_Homo sapiens_hsa050311.75710872
21Linoleic acid metabolism_Homo sapiens_hsa005911.74735770
22Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.74516169
23Mismatch repair_Homo sapiens_hsa034301.70018009
24Collecting duct acid secretion_Homo sapiens_hsa049661.66642144
25Basal transcription factors_Homo sapiens_hsa030221.65580365
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.61345650
27Phototransduction_Homo sapiens_hsa047441.61108911
28Serotonergic synapse_Homo sapiens_hsa047261.60155248
29Taste transduction_Homo sapiens_hsa047421.50690216
30Axon guidance_Homo sapiens_hsa043601.49909125
31Non-homologous end-joining_Homo sapiens_hsa034501.48124712
32Long-term depression_Homo sapiens_hsa047301.47442541
33Homologous recombination_Homo sapiens_hsa034401.47026065
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.41168150
35Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.37666314
36Gap junction_Homo sapiens_hsa045401.37576141
37Hippo signaling pathway_Homo sapiens_hsa043901.36498866
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.36048881
39Tryptophan metabolism_Homo sapiens_hsa003801.35270945
40Base excision repair_Homo sapiens_hsa034101.34874965
41Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.34561080
42Peroxisome_Homo sapiens_hsa041461.33904844
43Regulation of autophagy_Homo sapiens_hsa041401.33642125
44Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.32558996
45Long-term potentiation_Homo sapiens_hsa047201.31495145
46Insulin secretion_Homo sapiens_hsa049111.31307418
47Oocyte meiosis_Homo sapiens_hsa041141.31143114
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.29738273
49Oxidative phosphorylation_Homo sapiens_hsa001901.27776264
50mTOR signaling pathway_Homo sapiens_hsa041501.25765363
51Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.25391422
52Fatty acid elongation_Homo sapiens_hsa000621.24773180
53Wnt signaling pathway_Homo sapiens_hsa043101.19802407
54mRNA surveillance pathway_Homo sapiens_hsa030151.19387127
55ErbB signaling pathway_Homo sapiens_hsa040121.18904916
56Cholinergic synapse_Homo sapiens_hsa047251.18687717
57Caffeine metabolism_Homo sapiens_hsa002321.18287471
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.16361010
59Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.15197431
60Chemical carcinogenesis_Homo sapiens_hsa052041.14627641
61Selenocompound metabolism_Homo sapiens_hsa004501.13748157
62Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12327675
63Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.10139455
64Cocaine addiction_Homo sapiens_hsa050301.09647960
65Steroid hormone biosynthesis_Homo sapiens_hsa001401.08241117
66Cardiac muscle contraction_Homo sapiens_hsa042601.08050937
67RNA degradation_Homo sapiens_hsa030181.07139985
68Vibrio cholerae infection_Homo sapiens_hsa051101.07018157
69RNA polymerase_Homo sapiens_hsa030201.06612983
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.02779448
71Primary bile acid biosynthesis_Homo sapiens_hsa001201.01822040
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.00815470
73Parkinsons disease_Homo sapiens_hsa050120.99277676
74Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99209375
75Basal cell carcinoma_Homo sapiens_hsa052170.98847436
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96279376
77Salivary secretion_Homo sapiens_hsa049700.94798887
78Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.92414939
79Choline metabolism in cancer_Homo sapiens_hsa052310.87908991
80Fat digestion and absorption_Homo sapiens_hsa049750.87665705
81Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.87537029
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.86659830
83Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.86467671
84Oxytocin signaling pathway_Homo sapiens_hsa049210.86177653
85beta-Alanine metabolism_Homo sapiens_hsa004100.85658110
86Renin secretion_Homo sapiens_hsa049240.85612720
87Fatty acid degradation_Homo sapiens_hsa000710.84526468
88Butanoate metabolism_Homo sapiens_hsa006500.84419240
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.84251875
90Fatty acid metabolism_Homo sapiens_hsa012120.83934984
91Notch signaling pathway_Homo sapiens_hsa043300.83081969
92Arginine and proline metabolism_Homo sapiens_hsa003300.81913046
93Retinol metabolism_Homo sapiens_hsa008300.81870099
94Calcium signaling pathway_Homo sapiens_hsa040200.77955507
95Colorectal cancer_Homo sapiens_hsa052100.77671225
96Pyruvate metabolism_Homo sapiens_hsa006200.77248108
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76622094
98Proteasome_Homo sapiens_hsa030500.75713264
99Ovarian steroidogenesis_Homo sapiens_hsa049130.75712933
100GnRH signaling pathway_Homo sapiens_hsa049120.74436202
101Aldosterone synthesis and secretion_Homo sapiens_hsa049250.74065049
102Alzheimers disease_Homo sapiens_hsa050100.73198543
103Melanogenesis_Homo sapiens_hsa049160.72864978
104Maturity onset diabetes of the young_Homo sapiens_hsa049500.72578922
105Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.72560018
106Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.71978356
107Metabolic pathways_Homo sapiens_hsa011000.70800153
108Cysteine and methionine metabolism_Homo sapiens_hsa002700.68791212
109Steroid biosynthesis_Homo sapiens_hsa001000.67027480
110Tight junction_Homo sapiens_hsa045300.66978192
111Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66067591
112ABC transporters_Homo sapiens_hsa020100.64488038
113One carbon pool by folate_Homo sapiens_hsa006700.64071576
114Glutathione metabolism_Homo sapiens_hsa004800.63873633
115Gastric acid secretion_Homo sapiens_hsa049710.63477390
116Biosynthesis of amino acids_Homo sapiens_hsa012300.62225060
117Huntingtons disease_Homo sapiens_hsa050160.61088880
118Estrogen signaling pathway_Homo sapiens_hsa049150.60133095
119MAPK signaling pathway_Homo sapiens_hsa040100.59986979
120Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58789393
121TGF-beta signaling pathway_Homo sapiens_hsa043500.57818157
122Ether lipid metabolism_Homo sapiens_hsa005650.56595432
123Dorso-ventral axis formation_Homo sapiens_hsa043200.56530338
124Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.56477089
125Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55869666
126Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.55205114
127Purine metabolism_Homo sapiens_hsa002300.53451257
128Arachidonic acid metabolism_Homo sapiens_hsa005900.52701922
129cAMP signaling pathway_Homo sapiens_hsa040240.51546452
130Alcoholism_Homo sapiens_hsa050340.50532533
131Glycerolipid metabolism_Homo sapiens_hsa005610.50205477
132Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49976087
133Sulfur metabolism_Homo sapiens_hsa009200.49294965
134Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.45938728
135Ras signaling pathway_Homo sapiens_hsa040140.45578183
136Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.44474642
137Spliceosome_Homo sapiens_hsa030400.43017065
138Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.42903014
139Endocytosis_Homo sapiens_hsa041440.41807472
140Nucleotide excision repair_Homo sapiens_hsa034200.41101774
141Glioma_Homo sapiens_hsa052140.40316118
142Endometrial cancer_Homo sapiens_hsa052130.39261704
143Insulin signaling pathway_Homo sapiens_hsa049100.38777363
144Folate biosynthesis_Homo sapiens_hsa007900.35803052
145Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.34321809
146Thyroid hormone synthesis_Homo sapiens_hsa049180.32969247
147Lysine degradation_Homo sapiens_hsa003100.32300924
148Fanconi anemia pathway_Homo sapiens_hsa034600.31624222
149AMPK signaling pathway_Homo sapiens_hsa041520.31615587
150Type II diabetes mellitus_Homo sapiens_hsa049300.31208294
151Glucagon signaling pathway_Homo sapiens_hsa049220.30632559
152Adherens junction_Homo sapiens_hsa045200.30258247
153Renal cell carcinoma_Homo sapiens_hsa052110.28260445

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