ZFP36L2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.45358211
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.45358211
3ribosomal small subunit assembly (GO:0000028)5.10631866
4positive regulation of gamma-delta T cell activation (GO:0046645)4.97885313
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.97072690
6* definitive hemopoiesis (GO:0060216)4.78692902
7antigen processing and presentation of endogenous antigen (GO:0019883)4.76856285
8Peyers patch development (GO:0048541)4.37103862
9mucosal-associated lymphoid tissue development (GO:0048537)4.37103862
10negative regulation of erythrocyte differentiation (GO:0045647)4.24012561
11viral transcription (GO:0019083)4.19841335
12megakaryocyte development (GO:0035855)4.15338992
13regulation of gamma-delta T cell differentiation (GO:0045586)4.05743752
14positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.96602506
15translational termination (GO:0006415)3.96077971
16positive regulation of B cell differentiation (GO:0045579)3.91235442
17negative regulation of phagocytosis (GO:0050765)3.79300668
18antigen processing and presentation via MHC class Ib (GO:0002475)3.75855754
19regulation of gamma-delta T cell activation (GO:0046643)3.73827769
20aggressive behavior (GO:0002118)3.62380449
21positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.50985683
22mature B cell differentiation involved in immune response (GO:0002313)3.40410610
23regulation of B cell differentiation (GO:0045577)3.40181820
24neutrophil activation involved in immune response (GO:0002283)3.39687233
25regulation of B cell receptor signaling pathway (GO:0050855)3.39445351
26ribosomal small subunit biogenesis (GO:0042274)3.37742199
27tolerance induction (GO:0002507)3.35333947
28translational elongation (GO:0006414)3.33227353
29regulation of alpha-beta T cell proliferation (GO:0046640)3.23198568
30SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.21456750
31positive thymic T cell selection (GO:0045059)3.19833591
32negative regulation of T cell mediated immunity (GO:0002710)3.19792871
33nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.17734905
34negative regulation of innate immune response (GO:0045824)3.16721098
35regulation of granulocyte differentiation (GO:0030852)3.16625887
36detection of bacterium (GO:0016045)3.16448447
37regulation of dendritic cell antigen processing and presentation (GO:0002604)3.15675913
38mature B cell differentiation (GO:0002335)3.14452496
39interferon-gamma production (GO:0032609)3.14047710
40protein targeting to ER (GO:0045047)3.12716396
41negative thymic T cell selection (GO:0045060)3.12631507
42negative T cell selection (GO:0043383)3.12324151
43response to peptidoglycan (GO:0032494)3.11216071
44positive regulation of T cell differentiation in thymus (GO:0033089)3.11092020
45cotranslational protein targeting to membrane (GO:0006613)3.11066234
46leukocyte aggregation (GO:0070486)3.07818667
47T cell homeostasis (GO:0043029)3.06828051
48viral life cycle (GO:0019058)3.06577962
49embryonic hemopoiesis (GO:0035162)3.06535100
50maturation of SSU-rRNA (GO:0030490)3.05123889
51regulation of erythrocyte differentiation (GO:0045646)3.03310112
52negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.02988859
53negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.02278614
54negative regulation of cell killing (GO:0031342)3.02278614
55regulation of germinal center formation (GO:0002634)3.02147520
56thymic T cell selection (GO:0045061)3.01966402
57detection of other organism (GO:0098543)3.01901568
58positive regulation of alpha-beta T cell proliferation (GO:0046641)3.00538972
59establishment of protein localization to endoplasmic reticulum (GO:0072599)2.98429291
60negative regulation of lymphocyte mediated immunity (GO:0002707)2.98185926
61positive regulation of antigen processing and presentation (GO:0002579)2.96948845
62response to muramyl dipeptide (GO:0032495)2.96755888
63negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.95885500
64RNA destabilization (GO:0050779)2.95851570
65regulation of female receptivity (GO:0045924)2.95610141
66lymph node development (GO:0048535)2.95598477
673-UTR-mediated mRNA stabilization (GO:0070935)2.95428099
68regulation of mast cell degranulation (GO:0043304)2.94593328
69regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.94033497
70neutrophil activation (GO:0042119)2.93875169
71response to interleukin-15 (GO:0070672)2.92927231
72B cell receptor signaling pathway (GO:0050853)2.90732105
73cellular response to interleukin-15 (GO:0071350)2.90419673
74protein localization to endoplasmic reticulum (GO:0070972)2.90012173
75regulation of interleukin-12 biosynthetic process (GO:0045075)2.88413705
76negative regulation of stress fiber assembly (GO:0051497)2.87841660
77negative regulation of granulocyte differentiation (GO:0030853)2.87749888
78defense response to protozoan (GO:0042832)2.87626062
79Arp2/3 complex-mediated actin nucleation (GO:0034314)2.87185009
80angiogenesis involved in wound healing (GO:0060055)2.83588113
81cellular protein complex disassembly (GO:0043624)2.81263054
82cellular response to exogenous dsRNA (GO:0071360)2.81208586
83germ cell migration (GO:0008354)2.80248509
84regulation of antigen processing and presentation (GO:0002577)2.79125676
85negative regulation of leukocyte mediated immunity (GO:0002704)2.78991013
86positive regulation of T cell differentiation (GO:0045582)2.77721753
87negative regulation of bone resorption (GO:0045779)2.77200126
88immunoglobulin mediated immune response (GO:0016064)2.74279270
89myeloid dendritic cell activation (GO:0001773)2.72944650
90positive regulation of B cell activation (GO:0050871)2.71780409
91female mating behavior (GO:0060180)2.71495911
92hepatocyte apoptotic process (GO:0097284)2.71466573
93T cell receptor signaling pathway (GO:0050852)2.70598565
94regulation of mast cell activation involved in immune response (GO:0033006)2.70178662
95regulation of interleukin-2 production (GO:0032663)2.70096445
96actin nucleation (GO:0045010)2.69691448
97positive regulation of alpha-beta T cell differentiation (GO:0046638)2.69503565
98T cell selection (GO:0045058)2.68892809
99positive regulation of histone deacetylation (GO:0031065)2.68849332
100positive regulation of lymphocyte differentiation (GO:0045621)2.68372739
101activated T cell proliferation (GO:0050798)2.67819294
102negative regulation of T-helper cell differentiation (GO:0045623)2.66491013
103negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.66491013
104negative regulation of B cell apoptotic process (GO:0002903)2.66291549
105regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.65944096
106positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.65936376
107lymphocyte homeostasis (GO:0002260)2.65454232
108B cell mediated immunity (GO:0019724)2.63970178
109T cell migration (GO:0072678)2.63854937
110response to protozoan (GO:0001562)2.63364597
111positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.63008734
112regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.62955101
113cellular extravasation (GO:0045123)2.62677434
114positive regulation of alpha-beta T cell activation (GO:0046635)2.62513535
115regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.62485222
116pinocytosis (GO:0006907)2.62159131
117translational initiation (GO:0006413)2.61582674
118regulation of interferon-beta biosynthetic process (GO:0045357)2.60986147
119positive regulation by symbiont of host defense response (GO:0052509)2.60208281
120modulation by symbiont of host defense response (GO:0052031)2.60208281
121modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.60208281
122modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.60208281
123positive regulation by organism of defense response of other organism involved in symbiotic interact2.60208281
124modulation by symbiont of host immune response (GO:0052553)2.60208281
125response to interferon-alpha (GO:0035455)2.60178964
126mast cell activation (GO:0045576)2.58450402
127positive regulation of erythrocyte differentiation (GO:0045648)2.58136158
128negative regulation of interleukin-12 production (GO:0032695)2.57458039
129positive regulation of granulocyte differentiation (GO:0030854)2.56959002
130protein complex disassembly (GO:0043241)2.56753159
131secretory granule organization (GO:0033363)2.56439906
132positive regulation of isotype switching (GO:0045830)2.53515022
133response to laminar fluid shear stress (GO:0034616)2.52934976
134leukocyte homeostasis (GO:0001776)2.52758811
135JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.51279185
136response to type I interferon (GO:0034340)2.51192912
137regulation of T cell receptor signaling pathway (GO:0050856)2.50849567
138positive T cell selection (GO:0043368)2.50414406
139platelet dense granule organization (GO:0060155)2.50339987
140positive regulation of protein deacetylation (GO:0090312)2.49707671
141response to interferon-beta (GO:0035456)2.46537430
142positive regulation of natural killer cell differentiation (GO:0032825)2.45928132
143erythrocyte maturation (GO:0043249)2.44083524
144cellular response to type I interferon (GO:0071357)2.42727066
145type I interferon signaling pathway (GO:0060337)2.42727066
146* nuclear-transcribed mRNA catabolic process (GO:0000956)2.40384616
147antigen receptor-mediated signaling pathway (GO:0050851)2.40195981
148positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.40065757

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.44478526
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.39309097
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human4.07826556
4* SCL_19346495_ChIP-Seq_HPC-7_Human3.90170985
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.67973269
6EGR1_19374776_ChIP-ChIP_THP-1_Human3.63928634
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.28234596
8* MYC_22102868_ChIP-Seq_BL_Human3.16309206
9TP63_17297297_ChIP-ChIP_HaCaT_Human2.94846914
10MYB_21317192_ChIP-Seq_ERMYB_Mouse2.70746103
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.70349795
12NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.65710521
13* VDR_21846776_ChIP-Seq_THP-1_Human2.60516086
14STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.54690045
15* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.46732173
16MYB_26560356_Chip-Seq_TH2_Human2.40617343
17* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.39431905
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.39103455
19SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.38901901
20* RUNX_20019798_ChIP-Seq_JUKART_Human2.37159314
21* TCF7_22412390_ChIP-Seq_EML_Mouse2.32683112
22BP1_19119308_ChIP-ChIP_Hs578T_Human2.31309796
23SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.30281630
24* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.28453840
25* MAF_26560356_Chip-Seq_TH1_Human2.28104931
26IRF8_21731497_ChIP-ChIP_J774_Mouse2.26037194
27NOTCH1_21737748_ChIP-Seq_TLL_Human2.18231986
28IRF8_27001747_Chip-Seq_BMDM_Mouse2.13840254
29* MYB_26560356_Chip-Seq_TH1_Human2.13213384
30STAT4_19710469_ChIP-ChIP_TH1__Mouse2.11763193
31SPI1_23547873_ChIP-Seq_NB4_Human2.11334583
32* VDR_24763502_ChIP-Seq_THP-1_Human2.09591606
33RUNX1_22412390_ChIP-Seq_EML_Mouse2.06643285
34UTX_26944678_Chip-Seq_JUKART_Human2.02356232
35IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.00897837
36BRD4_27068464_Chip-Seq_AML-cells_Mouse2.00453622
37ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.99513446
38FOXM1_23109430_ChIP-Seq_U2OS_Human1.98679601
39* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.97829481
40NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.73269688
41VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.67620862
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.65135934
43* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.61350786
44FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.60991583
45* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.57748966
46* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.56108671
47RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.53173992
48E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.52811347
49* ELK3_25401928_ChIP-Seq_HUVEC_Human1.51197481
50ELF1_17652178_ChIP-ChIP_JURKAT_Human1.49574839
51TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.49396999
52* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.48355625
53* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.47493879
54GATA2_22383799_ChIP-Seq_G1ME_Mouse1.46684032
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.46446181
56BCL6_27268052_Chip-Seq_Bcells_Human1.44546119
57* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.43451753
58ELF1_20517297_ChIP-Seq_JURKAT_Human1.39615593
59SPI1_23127762_ChIP-Seq_K562_Human1.38814121
60* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.38735168
61* KDM2B_26808549_Chip-Seq_DND41_Human1.38328026
62MAF_26560356_Chip-Seq_TH2_Human1.38309060
63STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.36985083
64* PU_27001747_Chip-Seq_BMDM_Mouse1.32351531
65E2F4_17652178_ChIP-ChIP_JURKAT_Human1.29928687
66LXR_22292898_ChIP-Seq_THP-1_Human1.29245675
67* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.27271883
68SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.25667306
69* LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.25557419
70FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.24852203
71GATA3_27048872_Chip-Seq_THYMUS_Human1.24700529
72PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.24613847
73PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.23633481
74GATA2_21666600_ChIP-Seq_HMVEC_Human1.21850328
75CIITA_25753668_ChIP-Seq_RAJI_Human1.21159654
76VDR_24787735_ChIP-Seq_THP-1_Human1.20686985
77PU.1_20513432_ChIP-Seq_Bcells_Mouse1.19983923
78GATA1_22025678_ChIP-Seq_K562_Human1.18928051
79ERG_20887958_ChIP-Seq_HPC-7_Mouse1.18628820
80* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.18380422
81HOXB4_20404135_ChIP-ChIP_EML_Mouse1.17484450
82* GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.17255947
83* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.16625293
84MYC_18555785_ChIP-Seq_MESCs_Mouse1.12952475
85* NCOR1_26117541_ChIP-Seq_K562_Human1.12615547
86TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11270347
87BCOR_27268052_Chip-Seq_Bcells_Human1.09983165
88* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06241948
89GATA1_19941827_ChIP-Seq_MEL_Mouse1.04883738
90SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04279519
91SA1_27219007_Chip-Seq_ERYTHROID_Human1.03661224
92PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03269512
93CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02514188
94GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02219943
95Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.01147655
96RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.99290486
97VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.98136046
98P68_20966046_ChIP-Seq_HELA_Human0.97186743
99SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.96305952
100SPI1_20517297_ChIP-Seq_HL60_Human0.96244997
101CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.96042842
102KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.96035320
103PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.95532662
104P300_27268052_Chip-Seq_Bcells_Human0.95284896
105* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.95023762
106CTCF_27219007_Chip-Seq_ERYTHROID_Human0.94286963
107CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.93983165
108* CTCF_21964334_ChIP-Seq_BJAB-B_Human0.92772003
109CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92639985
110* KDM2B_26808549_Chip-Seq_JURKAT_Human0.89017844
111CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.88638871
112TP63_19390658_ChIP-ChIP_HaCaT_Human0.87745064
113E2F1_21310950_ChIP-Seq_MCF-7_Human0.87276013
114PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.87181248
115* GATA2_19941826_ChIP-Seq_K562_Human0.86544270
116* ETS1_22383799_ChIP-Seq_G1ME_Mouse0.86161944
117* GATA1_19941826_ChIP-Seq_K562_Human0.85663737
118CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.85329413
119FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.84425367
120SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.83407581
121SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.83407581
122GATA3_26560356_Chip-Seq_TH2_Human0.83387051
123* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.83190689
124VDR_23849224_ChIP-Seq_CD4+_Human0.80099916
125* MYC_19079543_ChIP-ChIP_MESCs_Mouse0.77965538
126FOXP3_21729870_ChIP-Seq_TREG_Human0.77319167
127CLOCK_20551151_ChIP-Seq_293T_Human0.77227647

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002396_abnormal_hematopoietic_system3.23088890
2MP0001835_abnormal_antigen_presentation2.91881761
3MP0003763_abnormal_thymus_physiology2.77638905
4MP0004808_abnormal_hematopoietic_stem2.61619355
5MP0000685_abnormal_immune_system2.48473485
6MP0005671_abnormal_response_to2.46605489
7MP0001800_abnormal_humoral_immune2.38544041
8MP0003300_gastrointestinal_ulcer2.34271764
9MP0003436_decreased_susceptibility_to2.33975531
10MP0005464_abnormal_platelet_physiology2.33657787
11MP0002452_abnormal_antigen_presenting2.19945233
12MP0002166_altered_tumor_susceptibility2.18993439
13MP0005000_abnormal_immune_tolerance2.15943211
14MP0001873_stomach_inflammation2.15451943
15MP0003724_increased_susceptibility_to2.14222801
16MP0001853_heart_inflammation2.12003541
17MP0002420_abnormal_adaptive_immunity2.11641962
18* MP0002398_abnormal_bone_marrow2.11116365
19MP0001819_abnormal_immune_cell2.09601145
20MP0002723_abnormal_immune_serum2.09376104
21MP0001790_abnormal_immune_system2.06763262
22MP0005387_immune_system_phenotype2.06763262
23MP0005025_abnormal_response_to2.03893225
24MP0002419_abnormal_innate_immunity1.93149939
25MP0009785_altered_susceptibility_to1.92302951
26MP0010155_abnormal_intestine_physiology1.89792018
27* MP0005397_hematopoietic_system_phenotyp1.88247065
28* MP0001545_abnormal_hematopoietic_system1.88247065
29MP0010352_gastrointestinal_tract_polyps1.84380731
30MP0002722_abnormal_immune_system1.82881691
31MP0002405_respiratory_system_inflammati1.82578118
32MP0004947_skin_inflammation1.82150686
33* MP0000716_abnormal_immune_system1.81784503
34MP0003303_peritoneal_inflammation1.80664408
35MP0002148_abnormal_hypersensitivity_rea1.80484740
36* MP0000689_abnormal_spleen_morphology1.79051553
37MP0005174_abnormal_tail_pigmentation1.78820603
38MP0000490_abnormal_crypts_of1.77817239
39* MP0000465_gastrointestinal_hemorrhage1.75148448
40MP0002006_tumorigenesis1.73127406
41MP0009333_abnormal_splenocyte_physiolog1.71603999
42MP0000703_abnormal_thymus_morphology1.63640565
43* MP0002429_abnormal_blood_cell1.59364505
44MP0003866_abnormal_defecation1.53223699
45MP0006082_CNS_inflammation1.50809442
46MP0006054_spinal_hemorrhage1.50626793
47MP0001845_abnormal_inflammatory_respons1.40372749
48* MP0009278_abnormal_bone_marrow1.37607921
49MP0001851_eye_inflammation1.34772755
50MP0002933_joint_inflammation1.32415377
51MP0003279_aneurysm1.31954420
52MP0000858_altered_metastatic_potential1.30742034
53MP0003566_abnormal_cell_adhesion1.30119277
54MP0005645_abnormal_hypothalamus_physiol1.29020606
55MP0001533_abnormal_skeleton_physiology1.27907468
56MP0003828_pulmonary_edema1.26435283
57MP0003448_altered_tumor_morphology1.25429773
58MP0003806_abnormal_nucleotide_metabolis1.25235443
59MP0008007_abnormal_cellular_replicative1.24759032
60MP0005023_abnormal_wound_healing1.24240948
61MP0005075_abnormal_melanosome_morpholog1.18930720
62MP0004510_myositis1.17873892
63MP0002009_preneoplasia1.17167408
64MP0002877_abnormal_melanocyte_morpholog1.16480136
65MP0002060_abnormal_skin_morphology1.13484295
66MP0003191_abnormal_cellular_cholesterol1.12190081
67MP0002019_abnormal_tumor_incidence1.03575990
68MP0008961_abnormal_basal_metabolism1.03297908
69MP0009764_decreased_sensitivity_to1.01447847
70MP0003943_abnormal_hepatobiliary_system0.98041237
71MP0008469_abnormal_protein_level0.97898899
72MP0000383_abnormal_hair_follicle0.97165450
73MP0002998_abnormal_bone_remodeling0.97165392
74MP0003453_abnormal_keratinocyte_physiol0.97048318
75MP0001216_abnormal_epidermal_layer0.96918061
76MP0005076_abnormal_cell_differentiation0.96749369
77MP0008057_abnormal_DNA_replication0.95513862
78MP0010368_abnormal_lymphatic_system0.94736063
79MP0000343_altered_response_to0.94020656
80MP0003172_abnormal_lysosome_physiology0.93023010
81MP0002254_reproductive_system_inflammat0.92390794
82MP0008995_early_reproductive_senescence0.91486953
83MP0002132_abnormal_respiratory_system0.89803020
84MP0010307_abnormal_tumor_latency0.89694038
85MP0000681_abnormal_thyroid_gland0.89658234
86MP0008004_abnormal_stomach_pH0.88149226
87MP0003705_abnormal_hypodermis_morpholog0.87948839
88MP0003693_abnormal_embryo_hatching0.87919373
89MP0003077_abnormal_cell_cycle0.85589058
90MP0004381_abnormal_hair_follicle0.84860545
91MP0001879_abnormal_lymphatic_vessel0.84667745
92MP0001986_abnormal_taste_sensitivity0.83851288
93MP0002095_abnormal_skin_pigmentation0.83676485
94MP0009840_abnormal_foam_cell0.82033552
95MP0005390_skeleton_phenotype0.80402223
96MP0003183_abnormal_peptide_metabolism0.80131169
97MP0001191_abnormal_skin_condition0.79268528
98MP0005310_abnormal_salivary_gland0.78622427
99MP0000477_abnormal_intestine_morphology0.76694027
100* MP0009931_abnormal_skin_appearance0.76299752
101MP0005166_decreased_susceptibility_to0.76064462
102MP0010094_abnormal_chromosome_stability0.74652141
103MP0005058_abnormal_lysosome_morphology0.73108140
104MP0005084_abnormal_gallbladder_morpholo0.72962240
105MP0008260_abnormal_autophagy0.72930697
106MP0003795_abnormal_bone_structure0.72721621
107MP0000767_abnormal_smooth_muscle0.72502835
108MP0001243_abnormal_dermal_layer0.72363487
109MP0009765_abnormal_xenobiotic_induced0.72136065
110MP0003075_altered_response_to0.71873245
111MP0004264_abnormal_extraembryonic_tissu0.71519682
112MP0003656_abnormal_erythrocyte_physiolo0.70604643
113MP0002796_impaired_skin_barrier0.69407316
114MP0001663_abnormal_digestive_system0.68945657
115MP0000249_abnormal_blood_vessel0.65393924
116MP0004883_abnormal_blood_vessel0.65150913
117MP0002928_abnormal_bile_duct0.62817932
118MP0009763_increased_sensitivity_to0.61995714
119MP0010678_abnormal_skin_adnexa0.61985216
120MP0008873_increased_physiological_sensi0.61864006
121MP0003638_abnormal_response/metabolism_0.60733454
122MP0009379_abnormal_foot_pigmentation0.60045481
123MP0005381_digestive/alimentary_phenotyp0.56445689
124MP0005535_abnormal_body_temperature0.54971200
125MP0005164_abnormal_response_to0.52566667
126MP0009643_abnormal_urine_homeostasis0.52563366
127MP0001765_abnormal_ion_homeostasis0.51190566
128MP0001881_abnormal_mammary_gland0.51027499
129MP0002277_abnormal_respiratory_mucosa0.50183130
130MP0005451_abnormal_body_composition0.48941657
131MP0001764_abnormal_homeostasis0.48580090

Predicted human phenotypes

RankGene SetZ-score
1Thrombocytosis (HP:0001894)4.10476308
2IgM deficiency (HP:0002850)4.00295686
3Prolonged bleeding time (HP:0003010)3.99974618
4Myositis (HP:0100614)3.95717420
5Chronic otitis media (HP:0000389)3.80112790
6Elevated erythrocyte sedimentation rate (HP:0003565)3.76217248
7Severe combined immunodeficiency (HP:0004430)3.73282014
8Petechiae (HP:0000967)3.41014345
9Abnormal platelet function (HP:0011869)3.29030571
10Impaired platelet aggregation (HP:0003540)3.29030571
11Recurrent abscess formation (HP:0002722)3.28514502
12Recurrent viral infections (HP:0004429)3.20107941
13Cellulitis (HP:0100658)3.16505602
14Abnormality of cells of the erythroid lineage (HP:0012130)3.13098365
15Spontaneous hematomas (HP:0007420)3.10064800
16Abnormal delayed hypersensitivity skin test (HP:0002963)3.08917439
17Recurrent fungal infections (HP:0002841)3.08824817
18Eczematoid dermatitis (HP:0000976)3.04731752
19Epistaxis (HP:0000421)3.04003434
20Abnormality of the fingertips (HP:0001211)3.00231656
21Abnormal number of erythroid precursors (HP:0012131)3.00009539
22Orchitis (HP:0100796)2.98396977
23Recurrent bacterial skin infections (HP:0005406)2.98046308
24Spinal cord lesions (HP:0100561)2.92256603
25Syringomyelia (HP:0003396)2.92256603
26Seborrheic dermatitis (HP:0001051)2.89139014
27Recurrent bronchitis (HP:0002837)2.87184509
28Panhypogammaglobulinemia (HP:0003139)2.84036089
29Abnormality of T cells (HP:0002843)2.78872476
30Abnormal platelet volume (HP:0011876)2.78522141
31Pustule (HP:0200039)2.78172612
32Inflammation of the large intestine (HP:0002037)2.77359364
33Combined immunodeficiency (HP:0005387)2.75444970
34T lymphocytopenia (HP:0005403)2.73830222
35Acute myeloid leukemia (HP:0004808)2.73558477
36Increased IgM level (HP:0003496)2.73240037
37Abnormality of T cell physiology (HP:0011840)2.71500450
38Stomach cancer (HP:0012126)2.70733918
39Hypergammaglobulinemia (HP:0010702)2.70094038
40Gastrointestinal inflammation (HP:0004386)2.70022389
41Urticaria (HP:0001025)2.70010557
42Verrucae (HP:0200043)2.68302159
43Papilloma (HP:0012740)2.68302159
44Hypertensive crisis (HP:0100735)2.68278736
45Reticulocytopenia (HP:0001896)2.67562989
46Arterial thrombosis (HP:0004420)2.66949649
47Increased IgE level (HP:0003212)2.66776567
48Meningitis (HP:0001287)2.65559165
49Recurrent gram-negative bacterial infections (HP:0005420)2.65053259
50Nasal polyposis (HP:0100582)2.63818387
51Episodic fever (HP:0001954)2.60562238
52Abnormality of the nasal mucosa (HP:0000433)2.59884567
53Gingival bleeding (HP:0000225)2.57056260
54Abnormality of T cell number (HP:0011839)2.55003009
55Gastrointestinal infarctions (HP:0005244)2.53251607
56Optic neuritis (HP:0100653)2.52842289
57Retrobulbar optic neuritis (HP:0100654)2.52842289
58Hematochezia (HP:0002573)2.51400207
59Autoimmune thrombocytopenia (HP:0001973)2.46071309
60Prostate neoplasm (HP:0100787)2.43102717
61Periodontitis (HP:0000704)2.39870655
62Colitis (HP:0002583)2.36694716
63Interstitial pulmonary disease (HP:0006530)2.34987261
64Agammaglobulinemia (HP:0004432)2.34448602
65Chest pain (HP:0100749)2.34392780
66Aplasia/Hypoplasia of the thymus (HP:0010515)2.33592466
67Vasculitis (HP:0002633)2.33582296
68Recurrent cutaneous fungal infections (HP:0011370)2.33408510
69Chronic mucocutaneous candidiasis (HP:0002728)2.33408510
70Increased mean platelet volume (HP:0011877)2.31147332
71Recurrent skin infections (HP:0001581)2.27718197
72Thyroiditis (HP:0100646)2.25509908
73Leukocytosis (HP:0001974)2.22325716
74Menorrhagia (HP:0000132)2.20970197
75Metaphyseal dysplasia (HP:0100255)2.20946442
76Increased serum ferritin (HP:0003281)2.19298960
77Abnormality of the prostate (HP:0008775)2.19106537
78Osteolytic defects of the hand bones (HP:0009699)2.18525562
79Osteolytic defects of the phalanges of the hand (HP:0009771)2.18525562
80Abnormality of iron homeostasis (HP:0011031)2.17844655
81Gingivitis (HP:0000230)2.17056057
82Sepsis (HP:0100806)2.15722990
83Aplastic anemia (HP:0001915)2.15644642
84Chronic obstructive pulmonary disease (HP:0006510)2.14837706
85Obstructive lung disease (HP:0006536)2.14837706
86Spondylolisthesis (HP:0003302)2.13938396
87Mediastinal lymphadenopathy (HP:0100721)2.12711006
88Lymphopenia (HP:0001888)2.12186188
89Encephalitis (HP:0002383)2.11355600
90Skin rash (HP:0000988)2.11065338
91Pallor (HP:0000980)2.10906270
92Increased density of long bones (HP:0006392)2.06147812
93Joint swelling (HP:0001386)2.02923110
94Abnormality of cells of the lymphoid lineage (HP:0012140)2.02902452
95Abnormality of the heme biosynthetic pathway (HP:0010472)2.02847704
96Aortic aneurysm (HP:0004942)2.02719060
97Purpura (HP:0000979)2.02105853
98Skin ulcer (HP:0200042)2.00381725
99Hemoptysis (HP:0002105)1.99436550
100Abnormality of the pleura (HP:0002103)1.99196372
101Keratoconjunctivitis sicca (HP:0001097)1.99130539
102Increased neuronal autofluorescent lipopigment (HP:0002074)1.98649774
103Chronic diarrhea (HP:0002028)1.95921181
104Amaurosis fugax (HP:0100576)1.95604772
105B lymphocytopenia (HP:0010976)1.94567156
106Abnormality of B cell number (HP:0010975)1.94567156
107Bruising susceptibility (HP:0000978)1.94230043
108Increased cerebral lipofuscin (HP:0011813)1.93613965
109Alveolar cell carcinoma (HP:0006519)1.93019441
110Lymphoma (HP:0002665)1.92608670
111Growth hormone excess (HP:0000845)1.92186225
112Abnormality of male internal genitalia (HP:0000022)1.91959726
113Myelodysplasia (HP:0002863)1.91935680
114Acute lymphatic leukemia (HP:0006721)1.90025916
115IgG deficiency (HP:0004315)1.89903996
116Pulmonary infiltrates (HP:0002113)1.89328804
117IgA deficiency (HP:0002720)1.88152163
118Abnormality of the columella (HP:0009929)1.86663388
119Vacuolated lymphocytes (HP:0001922)1.86031285
120Abnormality of eosinophils (HP:0001879)1.85623146
121Osteomyelitis (HP:0002754)1.85429382
122Vertigo (HP:0002321)1.85057633
123Granulocytopenia (HP:0001913)1.82991767
124Abnormality of macrophages (HP:0004311)1.81728219
125Fatigue (HP:0012378)1.80731436
126Eosinophilia (HP:0001880)1.80251254
12711 pairs of ribs (HP:0000878)1.78045462
128Keratoconjunctivitis (HP:0001096)1.76088875
129Pulmonary embolism (HP:0002204)1.75826841
130Autoimmune hemolytic anemia (HP:0001890)1.75685011
131Stomatitis (HP:0010280)1.74763491

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.12257754
2EEF2K3.39757195
3TGFBR22.65217833
4TXK2.57759460
5MAP2K32.38654098
6STK102.36653180
7KIT2.24766109
8JAK32.23256885
9MAP3K112.18491573
10BTK2.09881154
11ZAP701.96801515
12TEC1.93192879
13PRPF4B1.92617468
14PKN21.88862442
15TRIB31.83384258
16SCYL21.80931094
17MAP3K131.80758346
18TYK21.76460933
19TGFBR11.63644766
20NME21.61771949
21ITK1.59655284
22LRRK21.57117118
23RPS6KA41.55318459
24IRAK41.52744048
25TBK11.52361262
26ERN11.51290564
27IKBKE1.51129371
28BLK1.50990744
29CSF1R1.49874467
30MAP3K101.49454964
31RPS6KB21.49147813
32IRAK31.45592795
33RIPK41.43894385
34TESK21.42921133
35FLT31.42177165
36MAP3K141.37714106
37TRPM71.31784599
38PIM11.31432942
39GRK61.30336528
40IKBKB1.29024113
41FGFR31.27691613
42BCKDK1.25534823
43HCK1.23110383
44SYK1.19481657
45LCK1.15879563
46MAP3K31.15435218
47NLK1.15104862
48CDK61.09638792
49CLK11.08995390
50DYRK1B1.07893488
51MAPK71.07734599
52MAP3K11.05398895
53EPHB11.05311392
54TNK21.03959340
55FGFR41.03155668
56TAOK31.01772765
57MAPKAPK31.00765240
58MATK1.00367655
59CSK0.99087143
60CHUK0.98562047
61PTK60.94981177
62CDK120.93941097
63NUAK10.93876845
64TIE10.92622964
65PIM20.90327583
66JAK10.88655910
67HIPK20.87281217
68TAOK20.85562547
69SIK30.84574506
70CDK40.84046255
71PRKCQ0.81310461
72RPS6KA60.78769385
73MAPKAPK50.78072015
74MST40.77442800
75VRK20.76587769
76JAK20.73989170
77LYN0.73944514
78CAMK1D0.73408588
79FES0.72615794
80CDK90.72134490
81MAPK120.68015171
82MKNK10.67468105
83PASK0.67058720
84RPS6KC10.66750294
85RPS6KL10.66750294
86PRKD20.66065364
87PAK40.65178439
88NEK90.64122486
89MAPK40.63947421
90MAP2K20.61261698
91MAP3K60.61237784
92SMG10.60302772
93MAPKAPK20.59316667
94STK40.57938134
95TTN0.52961824
96STK240.52615759
97MAPK150.51528924
98MAP3K80.51260043
99NEK20.51178511
100CDK70.50979142
101SIK10.50587626
102MAP4K20.50566785
103RIPK10.50473928
104TSSK60.49143430
105BMPR20.48932404
106TAOK10.47735058
107MAP3K70.44213201
108DYRK30.43739428
109EPHA30.43232616
110CDK80.43177266
111IRAK10.42296186
112MARK20.42002027
113MAPK30.41943859
114KDR0.41640019
115PDK10.40932458
116PAK20.40882738
117RPS6KA50.39796487
118STK30.39651462
119MARK30.39351850
120MAP2K60.39200023
121SIK20.38460169
122PIK3CG0.37805735
123MKNK20.37728271
124PDGFRB0.37170589
125PIK3CA0.36997494
126FYN0.36870171
127MAPK110.36752081
128STK380.36290013
129PRKCD0.35512141
130MELK0.34608558
131PRKD10.30611315
132RPS6KA20.29876377
133ABL10.28822044
134PRKG20.25684817
135IGF1R0.24397555

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.83419003
2Ribosome_Homo sapiens_hsa030102.54255515
3Leishmaniasis_Homo sapiens_hsa051402.48293799
4B cell receptor signaling pathway_Homo sapiens_hsa046622.23153346
5Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.16147141
6Osteoclast differentiation_Homo sapiens_hsa043802.14759014
7Antigen processing and presentation_Homo sapiens_hsa046122.09262504
8Measles_Homo sapiens_hsa051622.04744346
9NF-kappa B signaling pathway_Homo sapiens_hsa040641.99485756
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.96789571
11Hematopoietic cell lineage_Homo sapiens_hsa046401.95700504
12Type I diabetes mellitus_Homo sapiens_hsa049401.93009510
13Acute myeloid leukemia_Homo sapiens_hsa052211.69585863
14T cell receptor signaling pathway_Homo sapiens_hsa046601.69049375
15Jak-STAT signaling pathway_Homo sapiens_hsa046301.68848273
16DNA replication_Homo sapiens_hsa030301.65522537
17Toxoplasmosis_Homo sapiens_hsa051451.63526707
18Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.62357968
19Platelet activation_Homo sapiens_hsa046111.59579383
20Chronic myeloid leukemia_Homo sapiens_hsa052201.58468930
21Herpes simplex infection_Homo sapiens_hsa051681.57554166
22Transcriptional misregulation in cancer_Homo sapiens_hsa052021.57172858
23Toll-like receptor signaling pathway_Homo sapiens_hsa046201.49204232
24RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.44141981
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.43164087
26Shigellosis_Homo sapiens_hsa051311.41226567
27Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.40280151
28Leukocyte transendothelial migration_Homo sapiens_hsa046701.38958632
29Hepatitis B_Homo sapiens_hsa051611.37915652
30Staphylococcus aureus infection_Homo sapiens_hsa051501.37483627
31NOD-like receptor signaling pathway_Homo sapiens_hsa046211.32657430
32Malaria_Homo sapiens_hsa051441.31935157
33AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.31704539
34Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.29701358
35Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.29213997
36Pertussis_Homo sapiens_hsa051331.26868411
37Base excision repair_Homo sapiens_hsa034101.26105189
38TNF signaling pathway_Homo sapiens_hsa046681.22979883
39Influenza A_Homo sapiens_hsa051641.21680018
40Apoptosis_Homo sapiens_hsa042101.19713564
41Legionellosis_Homo sapiens_hsa051341.19307291
42Small cell lung cancer_Homo sapiens_hsa052221.18215966
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.12049872
44Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.11690845
45HTLV-I infection_Homo sapiens_hsa051661.09617987
46Other glycan degradation_Homo sapiens_hsa005111.08793548
47Chemokine signaling pathway_Homo sapiens_hsa040621.03612714
48Mismatch repair_Homo sapiens_hsa034301.02923685
49Pancreatic cancer_Homo sapiens_hsa052121.02803567
50Tuberculosis_Homo sapiens_hsa051521.00433100
51Glycosaminoglycan degradation_Homo sapiens_hsa005311.00310089
52Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.99715966
53Spliceosome_Homo sapiens_hsa030400.97190772
54Rheumatoid arthritis_Homo sapiens_hsa053230.96517744
55Notch signaling pathway_Homo sapiens_hsa043300.96206028
56Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.95227955
57Allograft rejection_Homo sapiens_hsa053300.94739772
58p53 signaling pathway_Homo sapiens_hsa041150.94273292
59Glycerophospholipid metabolism_Homo sapiens_hsa005640.93544274
60Viral myocarditis_Homo sapiens_hsa054160.88075714
61Non-small cell lung cancer_Homo sapiens_hsa052230.85948864
62Caffeine metabolism_Homo sapiens_hsa002320.85906277
63Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.84138673
64Prolactin signaling pathway_Homo sapiens_hsa049170.83885601
65Cell cycle_Homo sapiens_hsa041100.81965196
66Viral carcinogenesis_Homo sapiens_hsa052030.81651718
67Salmonella infection_Homo sapiens_hsa051320.81092855
68Non-homologous end-joining_Homo sapiens_hsa034500.80894154
69Epstein-Barr virus infection_Homo sapiens_hsa051690.80608872
70MicroRNAs in cancer_Homo sapiens_hsa052060.80475166
71Hepatitis C_Homo sapiens_hsa051600.80332275
72Colorectal cancer_Homo sapiens_hsa052100.79662221
73SNARE interactions in vesicular transport_Homo sapiens_hsa041300.78984173
74Graft-versus-host disease_Homo sapiens_hsa053320.78181948
75Neurotrophin signaling pathway_Homo sapiens_hsa047220.77626382
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75254317
77Arachidonic acid metabolism_Homo sapiens_hsa005900.75032790
78Pentose phosphate pathway_Homo sapiens_hsa000300.74686720
79Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.73007760
80Proteoglycans in cancer_Homo sapiens_hsa052050.71885675
81Asthma_Homo sapiens_hsa053100.70937435
82Thyroid cancer_Homo sapiens_hsa052160.69143541
83Focal adhesion_Homo sapiens_hsa045100.68792598
84Inositol phosphate metabolism_Homo sapiens_hsa005620.68270061
85RNA degradation_Homo sapiens_hsa030180.65917474
86Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65217677
87Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.63661311
88Pathways in cancer_Homo sapiens_hsa052000.63030573
89African trypanosomiasis_Homo sapiens_hsa051430.62863101
90Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62222633
91Phosphatidylinositol signaling system_Homo sapiens_hsa040700.61083108
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.60428859
93ECM-receptor interaction_Homo sapiens_hsa045120.59517372
94VEGF signaling pathway_Homo sapiens_hsa043700.58966524
95Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58909385
96Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.58867162
97Homologous recombination_Homo sapiens_hsa034400.57131718
98Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.56827343
99FoxO signaling pathway_Homo sapiens_hsa040680.56658671
100Autoimmune thyroid disease_Homo sapiens_hsa053200.55967793
101Nucleotide excision repair_Homo sapiens_hsa034200.55940642
102Regulation of actin cytoskeleton_Homo sapiens_hsa048100.54568044
103Amoebiasis_Homo sapiens_hsa051460.51695045
104Renin secretion_Homo sapiens_hsa049240.51485485
105Regulation of autophagy_Homo sapiens_hsa041400.50725597
106Prostate cancer_Homo sapiens_hsa052150.50264030
107HIF-1 signaling pathway_Homo sapiens_hsa040660.45645098
108MAPK signaling pathway_Homo sapiens_hsa040100.44928877
109Sphingolipid signaling pathway_Homo sapiens_hsa040710.43839328
110PI3K-Akt signaling pathway_Homo sapiens_hsa041510.42521052
111Adherens junction_Homo sapiens_hsa045200.41023164
112Insulin resistance_Homo sapiens_hsa049310.40847467
113Lysosome_Homo sapiens_hsa041420.40794297
114Choline metabolism in cancer_Homo sapiens_hsa052310.40048344
115Endometrial cancer_Homo sapiens_hsa052130.39495158
116Rap1 signaling pathway_Homo sapiens_hsa040150.38534424
117Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37022294
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36189829
119TGF-beta signaling pathway_Homo sapiens_hsa043500.36046945
120Endocytosis_Homo sapiens_hsa041440.35940598
121Fanconi anemia pathway_Homo sapiens_hsa034600.35355229
122Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.34955417
123Lysine degradation_Homo sapiens_hsa003100.34810789
124Phospholipase D signaling pathway_Homo sapiens_hsa040720.34787843
125Glycerolipid metabolism_Homo sapiens_hsa005610.29711987
126Adipocytokine signaling pathway_Homo sapiens_hsa049200.28818149
127mTOR signaling pathway_Homo sapiens_hsa041500.23211479
128Peroxisome_Homo sapiens_hsa041460.22799610
129Phagosome_Homo sapiens_hsa041450.19988037
130Linoleic acid metabolism_Homo sapiens_hsa005910.19476812
131Drug metabolism - other enzymes_Homo sapiens_hsa009830.17616403

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