ZFP64

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)4.45794634
2DNA replication initiation (GO:0006270)4.35744417
3behavioral response to nicotine (GO:0035095)4.35294832
4DNA deamination (GO:0045006)4.31254473
5DNA strand elongation (GO:0022616)4.27134188
6formation of translation preinitiation complex (GO:0001731)4.26175812
7telomere maintenance via semi-conservative replication (GO:0032201)4.24601389
8maturation of SSU-rRNA (GO:0030490)4.04846682
9DNA replication checkpoint (GO:0000076)4.01238591
10ribosomal small subunit assembly (GO:0000028)3.97887008
11nucleobase biosynthetic process (GO:0046112)3.86856390
12ribosome biogenesis (GO:0042254)3.84688335
13telomere maintenance via recombination (GO:0000722)3.70781845
14regulation of posttranscriptional gene silencing (GO:0060147)3.67047967
15regulation of gene silencing by miRNA (GO:0060964)3.67047967
16regulation of gene silencing by RNA (GO:0060966)3.67047967
17ribonucleoprotein complex biogenesis (GO:0022613)3.65187434
18DNA unwinding involved in DNA replication (GO:0006268)3.64083661
19protein localization to kinetochore (GO:0034501)3.59895095
20purine nucleobase biosynthetic process (GO:0009113)3.59673495
21folic acid-containing compound biosynthetic process (GO:0009396)3.58723709
22mitotic metaphase plate congression (GO:0007080)3.57999391
23viral transcription (GO:0019083)3.57140390
24ribosomal small subunit biogenesis (GO:0042274)3.56893345
25somatic diversification of immune receptors via somatic mutation (GO:0002566)3.55747843
26somatic hypermutation of immunoglobulin genes (GO:0016446)3.55747843
27telomere maintenance via telomere lengthening (GO:0010833)3.54249207
28IMP biosynthetic process (GO:0006188)3.49774041
29ribosomal large subunit biogenesis (GO:0042273)3.49143223
30translational termination (GO:0006415)3.47655244
31mitotic recombination (GO:0006312)3.45547356
32respiratory chain complex IV assembly (GO:0008535)3.42053287
33DNA replication-dependent nucleosome organization (GO:0034723)3.38789875
34DNA replication-dependent nucleosome assembly (GO:0006335)3.38789875
35protein complex biogenesis (GO:0070271)3.38140650
36pseudouridine synthesis (GO:0001522)3.37834722
37mitotic nuclear envelope disassembly (GO:0007077)3.37815928
38DNA double-strand break processing (GO:0000729)3.33673446
39mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.33395869
40mitochondrial respiratory chain complex I assembly (GO:0032981)3.33395869
41NADH dehydrogenase complex assembly (GO:0010257)3.33395869
42mitochondrial RNA metabolic process (GO:0000959)3.32709543
43regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.32290073
44platelet dense granule organization (GO:0060155)3.32187139
45ribosome assembly (GO:0042255)3.31980062
46regulation of nuclear cell cycle DNA replication (GO:0033262)3.31497084
47proteasome assembly (GO:0043248)3.30012192
48nucleotide-excision repair, DNA gap filling (GO:0006297)3.29864409
49protein-cofactor linkage (GO:0018065)3.29589120
50mitochondrial respiratory chain complex assembly (GO:0033108)3.28971864
51spliceosomal snRNP assembly (GO:0000387)3.28835871
52rRNA processing (GO:0006364)3.27120886
53translational initiation (GO:0006413)3.26926903
54kinetochore assembly (GO:0051382)3.25248008
55termination of RNA polymerase III transcription (GO:0006386)3.23702190
56transcription elongation from RNA polymerase III promoter (GO:0006385)3.23702190
57kinetochore organization (GO:0051383)3.22545020
58translational elongation (GO:0006414)3.22507018
59metaphase plate congression (GO:0051310)3.21669738
60viral mRNA export from host cell nucleus (GO:0046784)3.19156008
61maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.18185985
62rRNA metabolic process (GO:0016072)3.17353427
63SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.09461914
64regulation of double-strand break repair via homologous recombination (GO:0010569)3.08100845
65rRNA modification (GO:0000154)3.08093602
66transcription-coupled nucleotide-excision repair (GO:0006283)3.07941391
67regulation of helicase activity (GO:0051095)3.07596164
68CENP-A containing nucleosome assembly (GO:0034080)3.05258472
69membrane disassembly (GO:0030397)3.05009910
70nuclear envelope disassembly (GO:0051081)3.05009910
71chromatin remodeling at centromere (GO:0031055)3.04147094
72nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.03978446
73regulation of hippo signaling (GO:0035330)3.02710243
74nuclear pore organization (GO:0006999)3.02434223
75protein localization to chromosome, centromeric region (GO:0071459)3.01855738
76mismatch repair (GO:0006298)3.01040954
77cotranslational protein targeting to membrane (GO:0006613)2.98436695
78protein targeting to ER (GO:0045047)2.98234332
79establishment of chromosome localization (GO:0051303)2.97480727
80peptidyl-histidine modification (GO:0018202)2.95998203
81cytochrome complex assembly (GO:0017004)2.95584934
82replication fork processing (GO:0031297)2.93806715
83deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.90560120
84nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.88972026
85exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.88420657
86kynurenine metabolic process (GO:0070189)2.87516812
87telomere maintenance (GO:0000723)2.87502005
88telomere organization (GO:0032200)2.86803421
89meiotic chromosome segregation (GO:0045132)2.86265652
90DNA duplex unwinding (GO:0032508)2.84251780
91IMP metabolic process (GO:0046040)2.84083439
92DNA geometric change (GO:0032392)2.84030852
93DNA replication-independent nucleosome organization (GO:0034724)2.83262200
94DNA replication-independent nucleosome assembly (GO:0006336)2.83262200
95translation (GO:0006412)2.82122402
96negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.81888641
97viral life cycle (GO:0019058)2.81011400
98behavioral response to ethanol (GO:0048149)2.80878934
99negative regulation of chromosome segregation (GO:0051985)2.80497764
100histone H4-K12 acetylation (GO:0043983)2.80477502
101establishment of protein localization to endoplasmic reticulum (GO:0072599)2.79101521
102protein localization to endoplasmic reticulum (GO:0070972)2.77479957
103mannosylation (GO:0097502)2.77271595
104termination of RNA polymerase I transcription (GO:0006363)2.77261825
105protein K6-linked ubiquitination (GO:0085020)2.77044148
106cellular protein complex disassembly (GO:0043624)2.76993494
107regulation of translation in response to stress (GO:0043555)2.76550271
108tRNA aminoacylation for protein translation (GO:0006418)2.75694781
109maturation of 5.8S rRNA (GO:0000460)2.75359520
110transcription from RNA polymerase I promoter (GO:0006360)2.74855522
111tryptophan catabolic process (GO:0006569)2.74771882
112indole-containing compound catabolic process (GO:0042436)2.74771882
113indolalkylamine catabolic process (GO:0046218)2.74771882
114mitotic sister chromatid segregation (GO:0000070)2.74210537
115base-excision repair (GO:0006284)2.74195554
116negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.73757842
117negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.72757035
118negative regulation of sister chromatid segregation (GO:0033046)2.72757035
119negative regulation of mitotic sister chromatid separation (GO:2000816)2.72757035
120negative regulation of mitotic sister chromatid segregation (GO:0033048)2.72757035
121anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.70778624
122recombinational repair (GO:0000725)2.70252903
123DNA damage response, detection of DNA damage (GO:0042769)2.69685104
124amino acid activation (GO:0043038)2.69139000
125tRNA aminoacylation (GO:0043039)2.69139000
126establishment of integrated proviral latency (GO:0075713)2.68437178
127centriole replication (GO:0007099)2.68202114
128regulation of mitochondrial translation (GO:0070129)2.68191590
129transcription from RNA polymerase III promoter (GO:0006383)2.66716213
130piRNA metabolic process (GO:0034587)2.63347875
131L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.61617948
132double-strand break repair via homologous recombination (GO:0000724)2.60916110
133reciprocal meiotic recombination (GO:0007131)2.60769553
134reciprocal DNA recombination (GO:0035825)2.60769553
135ubiquinone metabolic process (GO:0006743)2.55751854
136transcription from mitochondrial promoter (GO:0006390)2.54361618
137tRNA processing (GO:0008033)2.53982644
138metallo-sulfur cluster assembly (GO:0031163)2.53964642
139iron-sulfur cluster assembly (GO:0016226)2.53964642
140anterograde synaptic vesicle transport (GO:0048490)2.53132794
141DNA methylation involved in gamete generation (GO:0043046)2.52356335
142regulation of centriole replication (GO:0046599)2.52336725
143cornea development in camera-type eye (GO:0061303)2.51933250
144chaperone-mediated protein transport (GO:0072321)2.48952184
145intraciliary transport (GO:0042073)2.48235447
146L-serine metabolic process (GO:0006563)2.48050892
147protein deneddylation (GO:0000338)2.47235146
148water-soluble vitamin biosynthetic process (GO:0042364)2.46988591
149cullin deneddylation (GO:0010388)2.45407538
150tRNA metabolic process (GO:0006399)2.41286837
151neural tube formation (GO:0001841)2.40688403
152preassembly of GPI anchor in ER membrane (GO:0016254)2.38614993
153tryptophan metabolic process (GO:0006568)2.37696624
154tRNA modification (GO:0006400)2.37394204
155nonmotile primary cilium assembly (GO:0035058)2.33289901
156ubiquinone biosynthetic process (GO:0006744)2.32430864
157outer ear morphogenesis (GO:0042473)2.32330459
158protein polyglutamylation (GO:0018095)2.31294583
159DNA catabolic process, exonucleolytic (GO:0000738)2.30594171
160negative regulation of telomere maintenance (GO:0032205)2.27843405
161regulation of glucokinase activity (GO:0033131)2.26624368
162regulation of hexokinase activity (GO:1903299)2.26624368
163gamma-aminobutyric acid transport (GO:0015812)2.26451033
164tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.25858168
165RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.25858168
166regulation of telomere maintenance (GO:0032204)2.25238543
167RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.25209404
168negative regulation of transcription regulatory region DNA binding (GO:2000678)2.24806852
169regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.24403813
170negative regulation of mRNA processing (GO:0050686)2.23346456
171regulation of mitotic spindle checkpoint (GO:1903504)2.21918114
172regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.21918114
173GMP metabolic process (GO:0046037)2.21665051
174histone exchange (GO:0043486)2.21538709
175detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.21423767
176single strand break repair (GO:0000012)2.20192327
177regulation of cilium movement (GO:0003352)2.19571329
178chromatin assembly (GO:0031497)2.19166691
179somite development (GO:0061053)2.18515749
180histone arginine methylation (GO:0034969)2.17663138
181regulation of centrosome cycle (GO:0046605)2.16839224

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.59570335
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.21952875
3ZNF274_21170338_ChIP-Seq_K562_Hela3.34859359
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.34302666
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.30175053
6E2F4_17652178_ChIP-ChIP_JURKAT_Human3.19739365
7MYC_19079543_ChIP-ChIP_MESCs_Mouse3.11826854
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.98696411
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.85375242
10MYC_18358816_ChIP-ChIP_MESCs_Mouse2.83310700
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.82583729
12* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.77977024
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.73288103
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.70286010
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.67636842
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.63148013
17VDR_22108803_ChIP-Seq_LS180_Human2.53401348
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.50723670
19NELFA_20434984_ChIP-Seq_ESCs_Mouse2.37470281
20HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.36202836
21XRN2_22483619_ChIP-Seq_HELA_Human2.28437273
22CREB1_15753290_ChIP-ChIP_HEK293T_Human2.28262222
23IGF1R_20145208_ChIP-Seq_DFB_Human2.26602098
24* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.22865124
25ELF1_17652178_ChIP-ChIP_JURKAT_Human2.22163538
26NANOG_18555785_ChIP-Seq_MESCs_Mouse2.11179581
27E2F1_18555785_ChIP-Seq_MESCs_Mouse2.10101411
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.07018278
29VDR_23849224_ChIP-Seq_CD4+_Human2.03082045
30MYC_18940864_ChIP-ChIP_HL60_Human1.99807069
31SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.99632363
32* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.92237862
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.91688379
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.91233211
35POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.88015009
36* SALL1_21062744_ChIP-ChIP_HESCs_Human1.85666539
37FOXP3_21729870_ChIP-Seq_TREG_Human1.84489680
38* EWS_26573619_Chip-Seq_HEK293_Human1.81177512
39DCP1A_22483619_ChIP-Seq_HELA_Human1.80631390
40EGR1_19374776_ChIP-ChIP_THP-1_Human1.78809142
41KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.77994734
42KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.77994734
43KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.77994734
44* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.77388494
45MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.76783299
46GABP_19822575_ChIP-Seq_HepG2_Human1.75712725
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.72508274
48IRF1_19129219_ChIP-ChIP_H3396_Human1.71695991
49TTF2_22483619_ChIP-Seq_HELA_Human1.71589965
50E2F1_21310950_ChIP-Seq_MCF-7_Human1.71552882
51* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.68892297
52* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.68430706
53GBX2_23144817_ChIP-Seq_PC3_Human1.67003354
54HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.66615524
55* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.66066327
56TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.56959573
57TP63_19390658_ChIP-ChIP_HaCaT_Human1.56000860
58HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.55536215
59MYC_22102868_ChIP-Seq_BL_Human1.54605403
60FUS_26573619_Chip-Seq_HEK293_Human1.52819676
61STAT3_1855785_ChIP-Seq_MESCs_Mouse1.52564045
62CIITA_25753668_ChIP-Seq_RAJI_Human1.52500297
63* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52039302
64* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.51443057
65* YY1_21170310_ChIP-Seq_MESCs_Mouse1.49971755
66AR_21909140_ChIP-Seq_LNCAP_Human1.47732557
67* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.44687263
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.44516469
69ZFP57_27257070_Chip-Seq_ESCs_Mouse1.44224774
70YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.43987912
71* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43917834
72ELK1_19687146_ChIP-ChIP_HELA_Human1.42245232
73PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.41863874
74KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.40666089
75* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40081186
76POU5F1_16153702_ChIP-ChIP_HESCs_Human1.38804097
77E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.38481660
78CBX2_27304074_Chip-Seq_ESCs_Mouse1.37175502
79KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.36394213
80TCF3_18692474_ChIP-Seq_MEFs_Mouse1.36036921
81FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.35690023
82SRF_21415370_ChIP-Seq_HL-1_Mouse1.34743355
83KDM5A_27292631_Chip-Seq_BREAST_Human1.32998283
84NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.31625611
85NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.31329929
86* EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.30872492
87SOX2_16153702_ChIP-ChIP_HESCs_Human1.28487379
88FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.28377262
89HOXB4_20404135_ChIP-ChIP_EML_Mouse1.28182085
90SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.27633399
91EZH2_22144423_ChIP-Seq_EOC_Human1.26019858
92TFEB_21752829_ChIP-Seq_HELA_Human1.23602952
93NOTCH1_21737748_ChIP-Seq_TLL_Human1.20577142
94SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.20373611
95TP53_22573176_ChIP-Seq_HFKS_Human1.19006870
96BMI1_23680149_ChIP-Seq_NPCS_Mouse1.18324092
97ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.18213941
98* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.17840548
99P300_19829295_ChIP-Seq_ESCs_Human1.17491146
100DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.17372180
101ERG_20887958_ChIP-Seq_HPC-7_Mouse1.15344315
102TAF15_26573619_Chip-Seq_HEK293_Human1.14652420
103NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.14214405
104POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12290005
105TCF3_18692474_ChIP-Seq_MESCs_Mouse1.11892201
106SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.11414041
107ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.09173956
108PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.08874941
109RNF2_27304074_Chip-Seq_NSC_Mouse1.08102777
110VDR_21846776_ChIP-Seq_THP-1_Human1.07558992
111FLI1_27457419_Chip-Seq_LIVER_Mouse1.07129348
112MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05348085
113ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.04464862
114* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.03965426
115ER_23166858_ChIP-Seq_MCF-7_Human1.02826063
116CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.02639176
117TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.02168773
118* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.02137238
119* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02103983
120CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01208280
121DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00978178
122* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.00010510
123* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.99992633
124CBP_20019798_ChIP-Seq_JUKART_Human0.99966023
125IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.99966023
126NANOG_16153702_ChIP-ChIP_HESCs_Human0.98326167
127PADI4_21655091_ChIP-ChIP_MCF-7_Human0.96776448
128E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96577958
129TP63_17297297_ChIP-ChIP_HaCaT_Human0.95010138
130ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.94114057
131* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.93885695
132NANOG_21062744_ChIP-ChIP_HESCs_Human0.93222707
133ELK1_22589737_ChIP-Seq_MCF10A_Human0.93216408
134CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.91275961
135NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.90228309
136FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.90169493
137CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.89675104
138GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.88591668
139RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.84559941
140HOXB7_26014856_ChIP-Seq_BT474_Human0.82592635
141FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.81998817
142PCGF2_27294783_Chip-Seq_ESCs_Mouse0.81397938
143SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.80848865
144POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.78471122
145TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78471122
146* AR_20517297_ChIP-Seq_VCAP_Human0.77043227

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.01378182
2MP0004957_abnormal_blastocyst_morpholog4.01937622
3MP0003111_abnormal_nucleus_morphology3.99317121
4MP0010094_abnormal_chromosome_stability3.84770782
5MP0008057_abnormal_DNA_replication3.60368753
6MP0003077_abnormal_cell_cycle3.51099746
7MP0008058_abnormal_DNA_repair3.23538628
8MP0008007_abnormal_cellular_replicative2.73959530
9MP0002102_abnormal_ear_morphology2.72561450
10MP0008932_abnormal_embryonic_tissue2.61149720
11MP0001529_abnormal_vocalization2.47606177
12MP0010352_gastrointestinal_tract_polyps2.42972422
13MP0010030_abnormal_orbit_morphology2.35172976
14MP0003786_premature_aging2.04785462
15MP0000350_abnormal_cell_proliferation2.02777213
16MP0002396_abnormal_hematopoietic_system2.01462172
17MP0002938_white_spotting1.99397469
18MP0000490_abnormal_crypts_of1.91893239
19MP0001730_embryonic_growth_arrest1.90954043
20MP0000566_synostosis1.85395743
21MP0004133_heterotaxia1.82567316
22MP0005645_abnormal_hypothalamus_physiol1.79476683
23MP0006292_abnormal_olfactory_placode1.77609249
24MP0000569_abnormal_digit_pigmentation1.77421955
25MP0010307_abnormal_tumor_latency1.71913869
26MP0002234_abnormal_pharynx_morphology1.58610866
27MP0005551_abnormal_eye_electrophysiolog1.58596225
28MP0005380_embryogenesis_phenotype1.55310556
29MP0001672_abnormal_embryogenesis/_devel1.55310556
30MP0001697_abnormal_embryo_size1.52022942
31MP0002085_abnormal_embryonic_tissue1.51519673
32MP0009333_abnormal_splenocyte_physiolog1.48414608
33MP0000631_abnormal_neuroendocrine_gland1.46471310
34MP0005646_abnormal_pituitary_gland1.44332543
35MP0004142_abnormal_muscle_tone1.42126366
36MP0000372_irregular_coat_pigmentation1.40468927
37MP0002084_abnormal_developmental_patter1.39911172
38MP0002080_prenatal_lethality1.39444115
39MP0004197_abnormal_fetal_growth/weight/1.39250880
40MP0008789_abnormal_olfactory_epithelium1.39113102
41MP0003787_abnormal_imprinting1.37605151
42MP0002653_abnormal_ependyma_morphology1.34981885
43MP0002086_abnormal_extraembryonic_tissu1.34093211
44MP0003984_embryonic_growth_retardation1.33579781
45MP0002233_abnormal_nose_morphology1.33378615
46MP0002019_abnormal_tumor_incidence1.33291141
47MP0002163_abnormal_gland_morphology1.33047803
48MP0003136_yellow_coat_color1.32992318
49MP0000313_abnormal_cell_death1.31316201
50MP0002088_abnormal_embryonic_growth/wei1.31090263
51MP0003806_abnormal_nucleotide_metabolis1.30732554
52MP0002736_abnormal_nociception_after1.29521091
53MP0003941_abnormal_skin_development1.29506887
54MP0003763_abnormal_thymus_physiology1.28035099
55MP0002184_abnormal_innervation1.24908384
56MP0003718_maternal_effect1.24626859
57MP0000647_abnormal_sebaceous_gland1.23211620
58MP0001293_anophthalmia1.22597357
59MP0003119_abnormal_digestive_system1.21637061
60MP0003123_paternal_imprinting1.21519393
61MP0000778_abnormal_nervous_system1.19888442
62MP0000049_abnormal_middle_ear1.19320851
63MP0003942_abnormal_urinary_system1.18294691
64MP0002697_abnormal_eye_size1.17983144
65MP0008872_abnormal_physiological_respon1.15136954
66MP0001188_hyperpigmentation1.15052588
67MP0006035_abnormal_mitochondrial_morpho1.14368069
68MP0002638_abnormal_pupillary_reflex1.13209314
69MP0001984_abnormal_olfaction1.12683993
70MP0001968_abnormal_touch/_nociception1.12643489
71MP0006072_abnormal_retinal_apoptosis1.10670538
72MP0003315_abnormal_perineum_morphology1.10317177
73MP0003938_abnormal_ear_development1.09756636
74MP0000858_altered_metastatic_potential1.09672178
75MP0005174_abnormal_tail_pigmentation1.09636277
76MP0004808_abnormal_hematopoietic_stem1.08803114
77MP0000703_abnormal_thymus_morphology1.06378226
78MP0003861_abnormal_nervous_system1.06215393
79MP0002132_abnormal_respiratory_system1.05162295
80MP0003890_abnormal_embryonic-extraembry1.05004637
81MP0005076_abnormal_cell_differentiation1.04998331
82MP0000427_abnormal_hair_cycle1.04678089
83MP0005075_abnormal_melanosome_morpholog1.04110821
84MP0005187_abnormal_penis_morphology1.04020041
85MP0003385_abnormal_body_wall1.03338891
86MP0005499_abnormal_olfactory_system1.02742689
87MP0005394_taste/olfaction_phenotype1.02742689
88MP0009046_muscle_twitch1.02361870
89MP0002111_abnormal_tail_morphology1.01128002
90MP0005253_abnormal_eye_physiology1.00077198
91MP0004264_abnormal_extraembryonic_tissu1.00066707
92MP0003566_abnormal_cell_adhesion0.98490696
93MP0005023_abnormal_wound_healing0.96889730
94MP0002752_abnormal_somatic_nervous0.95603197
95MP0002722_abnormal_immune_system0.95256536
96MP0002398_abnormal_bone_marrow0.95215303
97MP0003567_abnormal_fetal_cardiomyocyte0.93743887
98MP0002177_abnormal_outer_ear0.93267070
99MP0001485_abnormal_pinna_reflex0.92772614
100MP0008995_early_reproductive_senescence0.92575309
101MP0002095_abnormal_skin_pigmentation0.92370529
102MP0001929_abnormal_gametogenesis0.91179396
103MP0002822_catalepsy0.90650080
104MP0000689_abnormal_spleen_morphology0.90643312
105MP0003283_abnormal_digestive_organ0.90209188
106MP0002272_abnormal_nervous_system0.89666351
107MP0002249_abnormal_larynx_morphology0.89251164
108MP0002557_abnormal_social/conspecific_i0.88773623
109MP0002282_abnormal_trachea_morphology0.88568029
110MP0003698_abnormal_male_reproductive0.87780411
111MP0001270_distended_abdomen0.86765390
112MP0002160_abnormal_reproductive_system0.86614278
113MP0000653_abnormal_sex_gland0.86077903
114MP0000955_abnormal_spinal_cord0.85982314
115MP0000383_abnormal_hair_follicle0.85004040
116MP0005501_abnormal_skin_physiology0.84852866
117MP0001286_abnormal_eye_development0.84212441
118MP0000534_abnormal_ureter_morphology0.84183307
119MP0008877_abnormal_DNA_methylation0.83767448
120MP0005391_vision/eye_phenotype0.83315122
121MP0006276_abnormal_autonomic_nervous0.82626800
122MP0000015_abnormal_ear_pigmentation0.82579482
123MP0002210_abnormal_sex_determination0.82111749
124MP0005397_hematopoietic_system_phenotyp0.81747768
125MP0001545_abnormal_hematopoietic_system0.81747768
126MP0000358_abnormal_cell_content/0.81377178
127MP0001324_abnormal_eye_pigmentation0.81353575
128MP0005195_abnormal_posterior_eye0.80823570
129MP0000026_abnormal_inner_ear0.79896326
130MP0003935_abnormal_craniofacial_develop0.79830731
131MP0000678_abnormal_parathyroid_gland0.76577200
132MP0009053_abnormal_anal_canal0.75790948
133MP0001849_ear_inflammation0.75142711
134MP0000428_abnormal_craniofacial_morphol0.75074508
135MP0000762_abnormal_tongue_morphology0.74443604
136MP0003937_abnormal_limbs/digits/tail_de0.74027349
137MP0002429_abnormal_blood_cell0.73887841
138MP0005389_reproductive_system_phenotype0.73037841
139MP0001919_abnormal_reproductive_system0.72833768
140MP0006054_spinal_hemorrhage0.72810431
141MP0001145_abnormal_male_reproductive0.72623290
142MP0000537_abnormal_urethra_morphology0.72505377
143MP0000477_abnormal_intestine_morphology0.72012647
144MP0005257_abnormal_intraocular_pressure0.71975908
145MP0003186_abnormal_redox_activity0.71496240
146MP0003755_abnormal_palate_morphology0.71289398
147MP0005384_cellular_phenotype0.71183753
148MP0005367_renal/urinary_system_phenotyp0.70785174
149MP0000516_abnormal_urinary_system0.70785174
150MP0002098_abnormal_vibrissa_morphology0.69355786
151MP0001186_pigmentation_phenotype0.68310703
152MP0005621_abnormal_cell_physiology0.68242206
153MP0002075_abnormal_coat/hair_pigmentati0.67917678
154MP0003121_genomic_imprinting0.67267937
155MP0001915_intracranial_hemorrhage0.67251768
156MP0009379_abnormal_foot_pigmentation0.66979990
157MP0002092_abnormal_eye_morphology0.66868531
158MP0002751_abnormal_autonomic_nervous0.65569950
159MP0001119_abnormal_female_reproductive0.65044342

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.65564695
2Reticulocytopenia (HP:0001896)4.18148736
3Chromosomal breakage induced by crosslinking agents (HP:0003221)4.00634036
4Chromsome breakage (HP:0040012)3.84184272
5Breast hypoplasia (HP:0003187)3.71580666
6Selective tooth agenesis (HP:0001592)3.65307261
7Degeneration of anterior horn cells (HP:0002398)3.36470041
8Abnormality of the anterior horn cell (HP:0006802)3.36470041
9Absent radius (HP:0003974)3.36216696
10Carpal bone hypoplasia (HP:0001498)3.36170267
11Pancreatic cysts (HP:0001737)3.35306444
12Medulloblastoma (HP:0002885)3.26392916
13Patellar aplasia (HP:0006443)3.20142488
14Ependymoma (HP:0002888)3.18953952
15Abnormality of cells of the erythroid lineage (HP:0012130)3.17122881
16Aplasia involving forearm bones (HP:0009822)3.16091719
17Absent forearm bone (HP:0003953)3.16091719
18Absent thumb (HP:0009777)3.07728162
19Agnosia (HP:0010524)3.06473970
20Abnormality of midbrain morphology (HP:0002418)3.06367383
21Molar tooth sign on MRI (HP:0002419)3.06367383
22Pancreatic fibrosis (HP:0100732)3.05175899
23Duplicated collecting system (HP:0000081)3.00031610
24Aplasia/Hypoplasia of the patella (HP:0006498)2.98705629
25Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.97021240
26Abnormality of alanine metabolism (HP:0010916)2.97021240
27Hyperalaninemia (HP:0003348)2.97021240
28Colon cancer (HP:0003003)2.96402453
29Abnormal number of erythroid precursors (HP:0012131)2.95313038
30Meckel diverticulum (HP:0002245)2.92636079
31Pendular nystagmus (HP:0012043)2.92140249
32Abnormality of the preputium (HP:0100587)2.89203018
33Type II lissencephaly (HP:0007260)2.88448912
34Abnormality of the ileum (HP:0001549)2.85989952
35True hermaphroditism (HP:0010459)2.83151971
36Lissencephaly (HP:0001339)2.78943111
37Rough bone trabeculation (HP:0100670)2.77534909
38Acute necrotizing encephalopathy (HP:0006965)2.73561989
39Cerebral hypomyelination (HP:0006808)2.70875930
40Abnormal number of incisors (HP:0011064)2.70396838
41Abnormality of chromosome stability (HP:0003220)2.70328392
42Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.69696697
43Oral leukoplakia (HP:0002745)2.68957231
44Hypoplasia of the pons (HP:0012110)2.68546041
45Aplasia/Hypoplasia of the uvula (HP:0010293)2.67779807
46Abnormality of the renal collecting system (HP:0004742)2.64961520
47Medial flaring of the eyebrow (HP:0010747)2.63538322
48Abnormal mitochondria in muscle tissue (HP:0008316)2.61295115
49Trismus (HP:0000211)2.59673936
50Rhabdomyosarcoma (HP:0002859)2.48162811
51Abnormality of the pons (HP:0007361)2.47129989
52Acute encephalopathy (HP:0006846)2.44409017
53Neoplasm of the oral cavity (HP:0100649)2.44338710
54Pallor (HP:0000980)2.42924278
55Chronic hepatic failure (HP:0100626)2.41368455
56Nephronophthisis (HP:0000090)2.41367840
57Small intestinal stenosis (HP:0012848)2.40302215
58Duodenal stenosis (HP:0100867)2.40302215
59Premature graying of hair (HP:0002216)2.40187369
6011 pairs of ribs (HP:0000878)2.39822044
61Abnormality of the labia minora (HP:0012880)2.39815643
62Myelodysplasia (HP:0002863)2.34460106
63Sclerocornea (HP:0000647)2.33964782
64Bone marrow hypocellularity (HP:0005528)2.33193899
65Preaxial hand polydactyly (HP:0001177)2.31194470
66Increased CSF lactate (HP:0002490)2.30713496
67Amaurosis fugax (HP:0100576)2.29376472
68Horseshoe kidney (HP:0000085)2.29003984
69Cystic liver disease (HP:0006706)2.27524029
70Aplastic anemia (HP:0001915)2.26957438
71Ectopic kidney (HP:0000086)2.26879554
72Triphalangeal thumb (HP:0001199)2.26568128
73Mitochondrial inheritance (HP:0001427)2.24537532
74Macrocytic anemia (HP:0001972)2.23798542
75Cerebellar dysplasia (HP:0007033)2.23206531
76Supernumerary spleens (HP:0009799)2.22669292
77Nephrogenic diabetes insipidus (HP:0009806)2.22512041
78Anencephaly (HP:0002323)2.20200811
79Congenital primary aphakia (HP:0007707)2.18780669
80Gait imbalance (HP:0002141)2.18654393
81Aplasia/Hypoplasia of the sacrum (HP:0008517)2.17586083
82Tracheoesophageal fistula (HP:0002575)2.14180132
83Postaxial foot polydactyly (HP:0001830)2.13499138
84Premature ovarian failure (HP:0008209)2.12228657
85Abnormality of the astrocytes (HP:0100707)2.12017978
86Astrocytoma (HP:0009592)2.12017978
87Neoplasm of the pancreas (HP:0002894)2.11902516
88Type I transferrin isoform profile (HP:0003642)2.11725461
89Basal cell carcinoma (HP:0002671)2.11070815
90Progressive macrocephaly (HP:0004481)2.07687239
91Abnormality of the renal medulla (HP:0100957)2.07615310
92Abnormality of abdominal situs (HP:0011620)2.06562917
93Abdominal situs inversus (HP:0003363)2.06562917
94Rib fusion (HP:0000902)2.06098295
95Ureteral duplication (HP:0000073)2.05110017
96Abnormality of the duodenum (HP:0002246)2.03545157
97Microretrognathia (HP:0000308)2.03407311
98Anophthalmia (HP:0000528)2.02506300
99Aplasia/Hypoplasia of the spleen (HP:0010451)2.01158983
100Congenital stationary night blindness (HP:0007642)2.01029457
101Bifid tongue (HP:0010297)2.00262551
102Small hand (HP:0200055)1.99813489
103Abnormality of DNA repair (HP:0003254)1.99807774
104Missing ribs (HP:0000921)1.99748505
105Concave nail (HP:0001598)1.99717258
106Sloping forehead (HP:0000340)1.98683911
107Neoplasm of striated muscle (HP:0009728)1.98037727
108Hepatocellular necrosis (HP:0001404)1.97301322
109Glioma (HP:0009733)1.97000933
110Abnormality of the renal cortex (HP:0011035)1.96858365
111Atresia of the external auditory canal (HP:0000413)1.96719281
112Genital tract atresia (HP:0001827)1.94902645
113Asplenia (HP:0001746)1.94787569
114Increased serum lactate (HP:0002151)1.94725998
115Vaginal atresia (HP:0000148)1.94710342
116Aplasia/hypoplasia of the humerus (HP:0006507)1.94031120
117Optic nerve coloboma (HP:0000588)1.93903356
118Short thumb (HP:0009778)1.93639171
119Impulsivity (HP:0100710)1.93420998
120Slender long bone (HP:0003100)1.92733210
121Dandy-Walker malformation (HP:0001305)1.92126939
122Hepatic necrosis (HP:0002605)1.91914646
123Abnormal trabecular bone morphology (HP:0100671)1.91735728
124Abnormal lung lobation (HP:0002101)1.89978898
125Aplasia/Hypoplasia of the tongue (HP:0010295)1.89362486
126Atrophy/Degeneration involving motor neurons (HP:0007373)1.88804950
127Severe muscular hypotonia (HP:0006829)1.86608752
128Clubbing of toes (HP:0100760)1.86579764
129Oligodactyly (hands) (HP:0001180)1.85936369
130Secondary amenorrhea (HP:0000869)1.85189883
131Proximal placement of thumb (HP:0009623)1.84614293
132Bile duct proliferation (HP:0001408)1.83614050
133Abnormal biliary tract physiology (HP:0012439)1.83614050
134Abnormality of pyrimidine metabolism (HP:0004353)1.82525694
135Deviation of the thumb (HP:0009603)1.82002650
136Duplication of thumb phalanx (HP:0009942)1.81719001
137Stenosis of the external auditory canal (HP:0000402)1.81702420
138Spinal muscular atrophy (HP:0007269)1.80600931
139Esophageal atresia (HP:0002032)1.79173438
140Acute lymphatic leukemia (HP:0006721)1.78721360
141Occipital encephalocele (HP:0002085)1.78660130
142Pachygyria (HP:0001302)1.78632181
143Postaxial hand polydactyly (HP:0001162)1.78406707
144Chorioretinal atrophy (HP:0000533)1.77658109
145IgM deficiency (HP:0002850)1.77433950
146Bilateral microphthalmos (HP:0007633)1.77224337
147Optic nerve hypoplasia (HP:0000609)1.76308930
148Abnormality of the carotid arteries (HP:0005344)1.75725205
149Lymphoma (HP:0002665)1.75664997
150Aplasia/Hypoplasia of the tibia (HP:0005772)1.75525554
151Cellular immunodeficiency (HP:0005374)1.74937802
152Hypoplasia of the capital femoral epiphysis (HP:0003090)1.74785448
153Cerebral edema (HP:0002181)1.74737217
154Hypoplasia of the radius (HP:0002984)1.74444068
155Retinal dysplasia (HP:0007973)1.73979459
156Poor coordination (HP:0002370)1.73728990
157Increased corneal curvature (HP:0100692)1.72821726
158Keratoconus (HP:0000563)1.72821726
159Astigmatism (HP:0000483)1.72170700
160Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.71791711
161Abnormal protein N-linked glycosylation (HP:0012347)1.71791711
162Abnormal protein glycosylation (HP:0012346)1.71791711
163Abnormal glycosylation (HP:0012345)1.71791711
164Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.68692045
165Hypoplastic pelvis (HP:0008839)1.68517208
166Prominent metopic ridge (HP:0005487)1.67598065
167Squamous cell carcinoma (HP:0002860)1.67455960
168Aganglionic megacolon (HP:0002251)1.67288887
169Polymicrogyria (HP:0002126)1.67070735
170Hyperglycinemia (HP:0002154)1.66455074
171Abnormality of the salivary glands (HP:0010286)1.64829599
172Oligodactyly (HP:0012165)1.63305360
173Tubular atrophy (HP:0000092)1.62638937
174Facial cleft (HP:0002006)1.62214806

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.77422458
2EPHA23.70086856
3WEE13.10732854
4EIF2AK13.09064865
5FRK2.96647221
6CDC72.87105339
7NUAK12.80781577
8VRK22.78057211
9TRIM282.58131098
10MAP4K22.54492957
11SRPK12.47848471
12NME22.42972663
13TTK2.34510550
14BMPR1B2.31270513
15WNK32.23410074
16STK162.23009152
17NME12.18613506
18RPS6KB22.17627923
19BCR2.15962779
20PASK2.13161852
21CDK122.12853563
22TLK12.10710667
23TSSK62.09976054
24PLK42.07754163
25EIF2AK32.03409897
26CDK72.01688734
27NEK21.83467003
28PLK11.81671286
29TESK21.80079309
30VRK11.74809475
31MAP3K101.73931491
32ACVR1B1.69746642
33ATR1.64851788
34PIM21.62078699
35TAF11.61820677
36DYRK31.60372640
37CASK1.51133138
38AURKB1.49747159
39WNK41.47960124
40TNIK1.43216011
41GRK11.43199414
42FLT31.42152050
43STK101.42121816
44SIK21.38843014
45ADRBK21.38022475
46CHEK21.36780455
47CSNK1G31.35206362
48AURKA1.32203055
49MAPKAPK31.29908546
50CSNK1A1L1.29381193
51NEK11.27673285
52BRSK21.25560040
53CSNK1G11.24129581
54PINK11.22519618
55CSNK1G21.20993461
56BCKDK1.20878927
57TGFBR11.20594247
58MAP2K71.20166821
59PLK31.15824363
60ZAK1.15811765
61PAK41.15586273
62EEF2K1.14705142
63MAP3K81.13945908
64MKNK11.13316030
65PIM11.13070847
66MAP3K41.09012740
67CHEK11.08405686
68CDK41.07292972
69LATS11.05067987
70INSRR0.98900404
71RPS6KA40.98869783
72MAP4K10.96802880
73STK390.96510992
74NTRK20.95423009
75PRKCI0.92110393
76CAMK1D0.89646843
77BRD40.86490712
78SCYL20.86216496
79MAPK130.85761431
80PNCK0.85468618
81STK40.84935222
82CDK80.84602305
83CDK20.80223497
84IRAK30.79194939
85MKNK20.78189263
86EIF2AK20.77671746
87CAMK1G0.77388012
88MAP2K30.77377152
89ATM0.74830097
90TAOK30.74743420
91PRKCG0.73076953
92MAP3K110.72832320
93OXSR10.72132282
94CLK10.71380694
95MARK10.71377698
96MAP3K90.70560353
97LIMK10.70375317
98KDR0.69774927
99PAK30.68553447
100DYRK20.67577271
101ALK0.67483783
102RPS6KA50.63439406
103CSNK2A20.61929346
104CCNB10.61878676
105YES10.60278862
106PAK10.60164666
107CSNK2A10.59945730
108MUSK0.59863328
109BTK0.58355049
110ZAP700.57677879
111PRKCE0.57436208
112IKBKB0.56992648
113BRSK10.56895553
114IRAK40.55876556
115PDK20.54947855
116CSNK1A10.54360353
117MST40.54059416
118MINK10.53911827
119EPHA40.53730754
120MET0.52324239
121CDK30.51636015
122CDK10.51122191
123BRAF0.50765057
124AKT20.50686909
125PBK0.50682907
126MAP3K30.49241063
127SIK30.48875503
128MARK30.47947110
129STK38L0.46748080
130AKT30.46546072
131LRRK20.46369843
132TESK10.44687893
133MTOR0.43346454
134STK30.42004695
135JAK30.41068747
136CHUK0.40686271
137ERBB30.40277696
138ADRBK10.39661642
139RPS6KL10.39422558
140RPS6KC10.39422558
141PKN20.38300600
142CSNK1E0.38287077
143RPS6KA60.36638620
144PRKAA10.35361283
145MELK0.34514840
146CDK60.34402729
147NLK0.31637048
148TXK0.29690452
149MAPKAPK20.29143008
150GRK60.28327838
151TAOK20.27629951
152MAP2K20.27586363
153DAPK10.27395554
154MAPK10.26297742

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.61415113
2Mismatch repair_Homo sapiens_hsa034304.25122425
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.54499928
4Ribosome_Homo sapiens_hsa030103.51204954
5Spliceosome_Homo sapiens_hsa030403.14383879
6RNA polymerase_Homo sapiens_hsa030203.08370596
7Base excision repair_Homo sapiens_hsa034103.07068262
8Homologous recombination_Homo sapiens_hsa034403.02689313
9RNA transport_Homo sapiens_hsa030132.85607351
10Proteasome_Homo sapiens_hsa030502.83544498
11Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.75010900
12Nucleotide excision repair_Homo sapiens_hsa034202.73185835
13One carbon pool by folate_Homo sapiens_hsa006702.66015145
14Fanconi anemia pathway_Homo sapiens_hsa034602.44154800
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.38402254
16Cell cycle_Homo sapiens_hsa041102.34941092
17Pyrimidine metabolism_Homo sapiens_hsa002402.31107606
18Oxidative phosphorylation_Homo sapiens_hsa001902.17836685
19Non-homologous end-joining_Homo sapiens_hsa034502.14113987
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.05103474
21Phototransduction_Homo sapiens_hsa047441.89944316
22Basal transcription factors_Homo sapiens_hsa030221.88438869
23Parkinsons disease_Homo sapiens_hsa050121.82314714
24RNA degradation_Homo sapiens_hsa030181.76988800
25p53 signaling pathway_Homo sapiens_hsa041151.73125081
26Nicotine addiction_Homo sapiens_hsa050331.56839099
27mRNA surveillance pathway_Homo sapiens_hsa030151.55631714
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.47723599
29Butanoate metabolism_Homo sapiens_hsa006501.46544171
30Caffeine metabolism_Homo sapiens_hsa002321.37686814
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.35475522
32Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.29936039
33Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.24156794
34Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.23199995
35Purine metabolism_Homo sapiens_hsa002301.17167531
36Steroid biosynthesis_Homo sapiens_hsa001001.15738530
37Epstein-Barr virus infection_Homo sapiens_hsa051691.13854403
38Systemic lupus erythematosus_Homo sapiens_hsa053221.12815011
39Propanoate metabolism_Homo sapiens_hsa006401.11626889
40Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.07646040
41Alzheimers disease_Homo sapiens_hsa050101.03289065
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.98730583
43Viral carcinogenesis_Homo sapiens_hsa052030.97754947
44Pyruvate metabolism_Homo sapiens_hsa006200.96531513
45Folate biosynthesis_Homo sapiens_hsa007900.95220945
46Herpes simplex infection_Homo sapiens_hsa051680.94732069
47Lysine degradation_Homo sapiens_hsa003100.94354736
48Nitrogen metabolism_Homo sapiens_hsa009100.93693436
49Tryptophan metabolism_Homo sapiens_hsa003800.92421496
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.91847398
51Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.91834668
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.91130540
53Basal cell carcinoma_Homo sapiens_hsa052170.90277472
54Protein export_Homo sapiens_hsa030600.87623890
55HTLV-I infection_Homo sapiens_hsa051660.86999681
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.85671951
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.85535480
58Peroxisome_Homo sapiens_hsa041460.83423056
59Cyanoamino acid metabolism_Homo sapiens_hsa004600.82803869
60alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.82466171
61Primary immunodeficiency_Homo sapiens_hsa053400.79485632
62Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.78426755
63Antigen processing and presentation_Homo sapiens_hsa046120.75774160
64Linoleic acid metabolism_Homo sapiens_hsa005910.75291788
65Notch signaling pathway_Homo sapiens_hsa043300.74137740
66Sulfur relay system_Homo sapiens_hsa041220.73808918
67Vitamin B6 metabolism_Homo sapiens_hsa007500.71779024
68Drug metabolism - other enzymes_Homo sapiens_hsa009830.70280862
69Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.69607366
70Hippo signaling pathway_Homo sapiens_hsa043900.68211166
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.67785441
72Fatty acid elongation_Homo sapiens_hsa000620.67727679
73MicroRNAs in cancer_Homo sapiens_hsa052060.66490751
74Fatty acid metabolism_Homo sapiens_hsa012120.66323135
75Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.65168358
76beta-Alanine metabolism_Homo sapiens_hsa004100.64661302
77Steroid hormone biosynthesis_Homo sapiens_hsa001400.63311729
78Thyroid cancer_Homo sapiens_hsa052160.62849538
79Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.62477910
80Legionellosis_Homo sapiens_hsa051340.61532159
81Apoptosis_Homo sapiens_hsa042100.60368737
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.60120719
83Cardiac muscle contraction_Homo sapiens_hsa042600.59724529
84Selenocompound metabolism_Homo sapiens_hsa004500.59106741
85Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58685387
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.56989534
87Fatty acid biosynthesis_Homo sapiens_hsa000610.56734198
88Small cell lung cancer_Homo sapiens_hsa052220.54546500
89Ether lipid metabolism_Homo sapiens_hsa005650.53710777
90Hedgehog signaling pathway_Homo sapiens_hsa043400.53360637
91Measles_Homo sapiens_hsa051620.53020735
92ABC transporters_Homo sapiens_hsa020100.52912992
93Pentose phosphate pathway_Homo sapiens_hsa000300.51985022
94N-Glycan biosynthesis_Homo sapiens_hsa005100.51599499
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.50893271
96Shigellosis_Homo sapiens_hsa051310.49654382
97Bladder cancer_Homo sapiens_hsa052190.49219655
98Biosynthesis of amino acids_Homo sapiens_hsa012300.48879151
99Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.48522330
100Morphine addiction_Homo sapiens_hsa050320.48463665
101Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48238843
102Taste transduction_Homo sapiens_hsa047420.47838102
103Axon guidance_Homo sapiens_hsa043600.46831451
104Glutathione metabolism_Homo sapiens_hsa004800.46012199
105Cysteine and methionine metabolism_Homo sapiens_hsa002700.44925642
106Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43788911
107TGF-beta signaling pathway_Homo sapiens_hsa043500.43774441
108Acute myeloid leukemia_Homo sapiens_hsa052210.43462150
109Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42626354
110Oocyte meiosis_Homo sapiens_hsa041140.42244527
111Colorectal cancer_Homo sapiens_hsa052100.42147173
112Fructose and mannose metabolism_Homo sapiens_hsa000510.40496854
113Other glycan degradation_Homo sapiens_hsa005110.40237496
114Arachidonic acid metabolism_Homo sapiens_hsa005900.40234145
115GABAergic synapse_Homo sapiens_hsa047270.40199739
116Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.39614211
117Galactose metabolism_Homo sapiens_hsa000520.38814651
118Alcoholism_Homo sapiens_hsa050340.37824220
119Pathways in cancer_Homo sapiens_hsa052000.37028696
120Chemical carcinogenesis_Homo sapiens_hsa052040.36613811
121Hepatitis B_Homo sapiens_hsa051610.35800025
122Hematopoietic cell lineage_Homo sapiens_hsa046400.33098300
123Regulation of autophagy_Homo sapiens_hsa041400.33026493
124Retinol metabolism_Homo sapiens_hsa008300.32736174
125Fat digestion and absorption_Homo sapiens_hsa049750.32535138
126Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31539368
127Intestinal immune network for IgA production_Homo sapiens_hsa046720.29902105
128Glutamatergic synapse_Homo sapiens_hsa047240.28850676
129Arginine and proline metabolism_Homo sapiens_hsa003300.27796838
130Influenza A_Homo sapiens_hsa051640.27210669
131Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27085600
132RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.27052563
133Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.26756078
134Wnt signaling pathway_Homo sapiens_hsa043100.23494560
135Adherens junction_Homo sapiens_hsa045200.22190109
136Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.21967959
137Chronic myeloid leukemia_Homo sapiens_hsa052200.20897700
138Prostate cancer_Homo sapiens_hsa052150.20792191
139Huntingtons disease_Homo sapiens_hsa050160.18430926
140Melanoma_Homo sapiens_hsa052180.17906769
141PI3K-Akt signaling pathway_Homo sapiens_hsa041510.17622594
142Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16627936
143NOD-like receptor signaling pathway_Homo sapiens_hsa046210.16486147
144Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.15354753
145Allograft rejection_Homo sapiens_hsa053300.14441212
146Viral myocarditis_Homo sapiens_hsa054160.14328504
147Metabolic pathways_Homo sapiens_hsa011000.14149786
1482-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.14000698
149Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.12727309
150Jak-STAT signaling pathway_Homo sapiens_hsa046300.12459746

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