ZFP90

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the zinc finger protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the development of heart failure. Genome wide association studies have identified this gene among ulcerative colitis risk loci. Alternative splicing of this gene results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1auditory behavior (GO:0031223)5.84307507
2response to auditory stimulus (GO:0010996)5.05250822
3nucleobase catabolic process (GO:0046113)4.97646909
4presynaptic membrane assembly (GO:0097105)4.79548076
5regulation of sister chromatid cohesion (GO:0007063)4.59348610
6cell morphogenesis involved in neuron differentiation (GO:0048667)4.58870268
7epithelial cilium movement (GO:0003351)4.47490874
8presynaptic membrane organization (GO:0097090)4.45946700
9neural tube formation (GO:0001841)4.38378807
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.37260217
11postsynaptic membrane organization (GO:0001941)4.19270196
12cellular response to prostaglandin stimulus (GO:0071379)4.12533290
13neuron cell-cell adhesion (GO:0007158)4.12238473
14startle response (GO:0001964)4.07724726
15mechanosensory behavior (GO:0007638)4.03796394
16neuron recognition (GO:0008038)4.03657347
17innervation (GO:0060384)3.96685054
18cilium movement (GO:0003341)3.79590407
19dendritic spine morphogenesis (GO:0060997)3.77119074
20behavioral response to nicotine (GO:0035095)3.76222316
21transmission of nerve impulse (GO:0019226)3.67214090
22mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337)3.61446685
23ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043163.56429373
24antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.39788920
25protein localization to synapse (GO:0035418)3.37227022
26neurotransmitter-gated ion channel clustering (GO:0072578)3.35598011
27central nervous system neuron axonogenesis (GO:0021955)3.33420867
28mesenchymal-epithelial cell signaling (GO:0060638)3.20745189
29retinal ganglion cell axon guidance (GO:0031290)3.20690354
30cilium assembly (GO:0042384)3.19457218
31glial cell proliferation (GO:0014009)3.17568739
32regulation of collateral sprouting (GO:0048670)3.17062912
33negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.16623583
34vocalization behavior (GO:0071625)3.16262312
35synapse assembly (GO:0007416)3.16207202
36cilium organization (GO:0044782)3.15882043
37cilium or flagellum-dependent cell motility (GO:0001539)3.13997686
38cerebral cortex radially oriented cell migration (GO:0021799)3.10582289
39protein localization to cilium (GO:0061512)3.08692556
40axonemal dynein complex assembly (GO:0070286)3.05109937
41cilium morphogenesis (GO:0060271)3.02167825
42regulation of chemokine secretion (GO:0090196)3.00557389
43calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.00509377
44hindbrain development (GO:0030902)2.94907511
45pyrimidine dimer repair (GO:0006290)2.92062718
46nonmotile primary cilium assembly (GO:0035058)2.89922702
47negative regulation of axon guidance (GO:1902668)2.88963850
48ganglion development (GO:0061548)2.88566674
49establishment of nucleus localization (GO:0040023)2.88409463
50cranial nerve development (GO:0021545)2.87061694
51negative regulation of oligodendrocyte differentiation (GO:0048715)2.86456460
52intra-S DNA damage checkpoint (GO:0031573)2.86317886
53establishment of mitochondrion localization (GO:0051654)2.85801107
54neuromuscular synaptic transmission (GO:0007274)2.85609270
55negative regulation of cytosolic calcium ion concentration (GO:0051481)2.84165050
56positive regulation of synapse assembly (GO:0051965)2.83059020
57forebrain neuron differentiation (GO:0021879)2.81312420
58cell migration in hindbrain (GO:0021535)2.78384790
59regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.77610095
60dendrite development (GO:0016358)2.77473328
61dorsal/ventral axis specification (GO:0009950)2.76479074
62gamma-aminobutyric acid transport (GO:0015812)2.73713844
63negative regulation of chondrocyte differentiation (GO:0032331)2.73540234
64olfactory bulb development (GO:0021772)2.73308432
65tongue development (GO:0043586)2.72732007
66regulation of feeding behavior (GO:0060259)2.72219374
67regulation of cilium movement (GO:0003352)2.71935309
68negative chemotaxis (GO:0050919)2.71757852
69glycosphingolipid biosynthetic process (GO:0006688)2.70618802
70dendrite morphogenesis (GO:0048813)2.69789663
71cochlea development (GO:0090102)2.68450398
72axoneme assembly (GO:0035082)2.67235879
73smoothened signaling pathway (GO:0007224)2.65998480
74somite development (GO:0061053)2.65994838
75head development (GO:0060322)2.64917848
76negative regulation of synaptic transmission, GABAergic (GO:0032229)2.62620382
77dentate gyrus development (GO:0021542)2.62340855
78epithelial cell differentiation involved in kidney development (GO:0035850)2.62192237
79cellular component assembly involved in morphogenesis (GO:0010927)2.61564493
80neuron fate determination (GO:0048664)2.60308981
81G-protein coupled receptor internalization (GO:0002031)2.60215522
82motile cilium assembly (GO:0044458)2.60176989
83regulation of short-term neuronal synaptic plasticity (GO:0048172)2.60037509
84spinal cord association neuron differentiation (GO:0021527)2.59460986
85limb development (GO:0060173)2.59278189
86appendage development (GO:0048736)2.59278189
87inositol phosphate catabolic process (GO:0071545)2.59257095
88neuronal ion channel clustering (GO:0045161)2.58934179
89heparin biosynthetic process (GO:0030210)2.58494358
90heparin metabolic process (GO:0030202)2.58494358
91detection of calcium ion (GO:0005513)2.55769074
92histone H3-K9 methylation (GO:0051567)2.54497684
93regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.54474982
94negative regulation of dendrite development (GO:2000171)2.54154545
95axon extension (GO:0048675)2.54036800
96establishment of viral latency (GO:0019043)2.53588143
97cell proliferation in forebrain (GO:0021846)2.53390895
98regulation of telomere maintenance (GO:0032204)2.52126801
99mesenchymal cell differentiation (GO:0048762)2.50152675
100adult walking behavior (GO:0007628)2.49585274
101proximal/distal pattern formation (GO:0009954)2.48568960
102regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.47913410
103positive regulation of dendritic spine morphogenesis (GO:0061003)2.47339618
104hippocampus development (GO:0021766)2.47068302
105negative regulation of axonogenesis (GO:0050771)2.46949670
106positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.46335078
107regulation of axon guidance (GO:1902667)2.45298057
108lens morphogenesis in camera-type eye (GO:0002089)2.44602443
109neuron migration (GO:0001764)2.43777755
110sympathetic nervous system development (GO:0048485)2.41709697
111synapse organization (GO:0050808)2.41686437
112protein polyglutamylation (GO:0018095)2.41263148
113behavioral response to ethanol (GO:0048149)2.41029284
114positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.40969633
115brain morphogenesis (GO:0048854)2.40076009
116regulation of dopamine secretion (GO:0014059)2.38507243
117axon extension involved in axon guidance (GO:0048846)2.37412282
118neuron projection extension involved in neuron projection guidance (GO:1902284)2.37412282
119cellular response to vitamin D (GO:0071305)2.34770741
120mesenchymal cell proliferation (GO:0010463)2.32947347
121positive regulation of interleukin-8 secretion (GO:2000484)2.32897972
122positive regulation of chemokine secretion (GO:0090197)2.31187548
123negative regulation of cell killing (GO:0031342)2.30936291
124negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.30936291
125mesenchymal to epithelial transition (GO:0060231)2.30032039
126regulation of somitogenesis (GO:0014807)2.29790594
127limb bud formation (GO:0060174)2.29680081
128regulation of monocyte differentiation (GO:0045655)2.26620384
129spinal cord development (GO:0021510)2.26482156
130regulation of phospholipid biosynthetic process (GO:0071071)2.26404991
131pyrimidine nucleobase catabolic process (GO:0006208)2.24887546
132regulation of helicase activity (GO:0051095)2.24775754
133layer formation in cerebral cortex (GO:0021819)2.23977140
134mitotic spindle assembly checkpoint (GO:0007094)2.22476321
135positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.21861356
136sequestering of actin monomers (GO:0042989)2.21378434
137gastrulation with mouth forming second (GO:0001702)2.20354326
138negative regulation of DNA-dependent DNA replication (GO:2000104)2.20338699
139negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.19016646
140negative regulation of sister chromatid segregation (GO:0033046)2.19016646
141negative regulation of mitotic sister chromatid separation (GO:2000816)2.19016646
142negative regulation of mitotic sister chromatid segregation (GO:0033048)2.19016646
143intraciliary transport (GO:0042073)2.17290439
144response to prostaglandin (GO:0034694)2.16353894
145outer ear morphogenesis (GO:0042473)2.15765403
146embryonic forelimb morphogenesis (GO:0035115)2.15593671
147regulation of interferon-beta biosynthetic process (GO:0045357)2.15095351
148pancreas development (GO:0031016)2.12800630
149embryonic skeletal joint morphogenesis (GO:0060272)2.12476418
150negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.12399858
151phagocytosis, engulfment (GO:0006911)2.12055653
152establishment of integrated proviral latency (GO:0075713)2.11751637
153forebrain morphogenesis (GO:0048853)2.10682867
154negative regulation of microtubule polymerization (GO:0031115)2.10578035
155central nervous system projection neuron axonogenesis (GO:0021952)2.09988373
156cell differentiation in spinal cord (GO:0021515)2.08714939
157interkinetic nuclear migration (GO:0022027)2.08552117
158response to pheromone (GO:0019236)2.08195654
159mitotic spindle checkpoint (GO:0071174)2.07761956
160mesenchymal cell differentiation involved in kidney development (GO:0072161)2.07759161
161mesenchymal cell differentiation involved in renal system development (GO:2001012)2.07759161
162spindle assembly checkpoint (GO:0071173)2.07405917
163negative regulation of chromosome segregation (GO:0051985)2.07245824
164heparan sulfate proteoglycan biosynthetic process (GO:0015012)2.06893079
165neural tube development (GO:0021915)2.05040500
166nerve development (GO:0021675)2.04976806
167forelimb morphogenesis (GO:0035136)2.04111196
168regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.03002887
169regulation of interleukin-8 secretion (GO:2000482)2.02797183
170histamine secretion (GO:0001821)2.02469821
171poly(A)+ mRNA export from nucleus (GO:0016973)2.02463370
172kidney morphogenesis (GO:0060993)2.02345841
173DNA demethylation (GO:0080111)2.02328148
174lens development in camera-type eye (GO:0002088)2.01592439
175immunoglobulin mediated immune response (GO:0016064)2.01084946
176lymphoid progenitor cell differentiation (GO:0002320)1.99907180
177serotonin receptor signaling pathway (GO:0007210)1.97371823
178axonal fasciculation (GO:0007413)1.96897155
179DNA double-strand break processing (GO:0000729)1.95402305
180regulation of Rac GTPase activity (GO:0032314)1.94622437
181axonogenesis (GO:0007409)1.94536721
182lung-associated mesenchyme development (GO:0060484)1.94427370
183microglial cell activation (GO:0001774)1.94115290
184B cell mediated immunity (GO:0019724)1.93884638

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse3.92343365
2EZH2_22144423_ChIP-Seq_EOC_Human3.13791162
3TP63_19390658_ChIP-ChIP_HaCaT_Human2.95905047
4IRF8_21731497_ChIP-ChIP_J774_Mouse2.91945825
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.89189349
6VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.86633562
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.64443539
8E2F7_22180533_ChIP-Seq_HELA_Human2.60111043
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.58509476
10GBX2_23144817_ChIP-Seq_PC3_Human2.42754873
11POU5F1_16153702_ChIP-ChIP_HESCs_Human2.41260235
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.34392796
13TAF15_26573619_Chip-Seq_HEK293_Human2.24988679
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.23781728
15JARID2_20064375_ChIP-Seq_MESCs_Mouse2.19238923
16IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.14444128
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.12609161
18CTBP1_25329375_ChIP-Seq_LNCAP_Human2.11725646
19CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.07847465
20EWS_26573619_Chip-Seq_HEK293_Human2.07693290
21PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.04800267
22BP1_19119308_ChIP-ChIP_Hs578T_Human1.97966651
23EED_16625203_ChIP-ChIP_MESCs_Mouse1.97668541
24VDR_22108803_ChIP-Seq_LS180_Human1.93746383
25IRF8_22096565_ChIP-ChIP_GC-B_Human1.93636370
26EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.89424233
27SMAD_19615063_ChIP-ChIP_OVARY_Human1.80505798
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.79741861
29BMI1_23680149_ChIP-Seq_NPCS_Mouse1.79166731
30* REST_21632747_ChIP-Seq_MESCs_Mouse1.77331204
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76311759
32JARID2_20075857_ChIP-Seq_MESCs_Mouse1.75537744
33RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.74572587
34ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.73602361
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73070597
36ER_23166858_ChIP-Seq_MCF-7_Human1.72084244
37SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.71154710
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70540237
39RNF2_27304074_Chip-Seq_ESCs_Mouse1.69855700
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.68813367
41SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.67632831
42GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.67510945
43WT1_19549856_ChIP-ChIP_CCG9911_Human1.67333333
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.67181900
45MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.66970798
46AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.65937854
47SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.65381011
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.60431380
49* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.58500690
50AR_21572438_ChIP-Seq_LNCaP_Human1.58070266
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.56944676
52* SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.56544478
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.56498369
54SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.54551345
55EZH2_18974828_ChIP-Seq_MESCs_Mouse1.54438518
56RNF2_18974828_ChIP-Seq_MESCs_Mouse1.54438518
57STAT3_23295773_ChIP-Seq_U87_Human1.53958933
58CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.53783129
59CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.53110270
60FLI1_27457419_Chip-Seq_LIVER_Mouse1.52715010
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.52308796
62P300_19829295_ChIP-Seq_ESCs_Human1.49390472
63FUS_26573619_Chip-Seq_HEK293_Human1.47580216
64WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.47217477
65STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.45650258
66AR_25329375_ChIP-Seq_VCAP_Human1.43708178
67RNF2_27304074_Chip-Seq_NSC_Mouse1.43074922
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.42517817
69CBP_20019798_ChIP-Seq_JUKART_Human1.42517817
70UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.39678825
71REST_18959480_ChIP-ChIP_MESCs_Mouse1.39634436
72TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.36987151
73BCAT_22108803_ChIP-Seq_LS180_Human1.34516376
74* TCF4_23295773_ChIP-Seq_U87_Human1.33158886
75RUNX2_22187159_ChIP-Seq_PCA_Human1.32201453
76TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.28643600
77NANOG_18555785_Chip-Seq_ESCs_Mouse1.26618019
78IRF8_27001747_Chip-Seq_BMDM_Mouse1.26361325
79KLF5_20875108_ChIP-Seq_MESCs_Mouse1.24662963
80PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22723069
81HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.21019526
82IRF1_19129219_ChIP-ChIP_H3396_Human1.20111165
83SOX2_21211035_ChIP-Seq_LN229_Gbm1.20028014
84NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17840683
85JUN_21703547_ChIP-Seq_K562_Human1.17496310
86TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16484495
87TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.16105524
88GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15262567
89SMAD3_21741376_ChIP-Seq_EPCs_Human1.14996240
90BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.14742461
91EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14455172
92CTBP2_25329375_ChIP-Seq_LNCAP_Human1.13300864
93TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12924700
94POU3F2_20337985_ChIP-ChIP_501MEL_Human1.12329780
95NFIB_24661679_ChIP-Seq_LUNG_Mouse1.11798370
96OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.11332796
97DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.11261762
98STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.10853105
99* FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.10461344
100EZH2_27294783_Chip-Seq_ESCs_Mouse1.09842299
101SOX2_16153702_ChIP-ChIP_HESCs_Human1.09653460
102CDX2_19796622_ChIP-Seq_MESCs_Mouse1.08868835
103KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08573672
104KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.08468172
105P53_22127205_ChIP-Seq_FIBROBLAST_Human1.08210499
106ARNT_22903824_ChIP-Seq_MCF-7_Human1.07942656
107CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07867128
108ZNF274_21170338_ChIP-Seq_K562_Hela1.07293785
109* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05101292
110MTF2_20144788_ChIP-Seq_MESCs_Mouse1.04832093
111TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.04207807
112DROSHA_22980978_ChIP-Seq_HELA_Human1.04168468
113P53_22387025_ChIP-Seq_ESCs_Mouse1.04114312
114PRDM14_20953172_ChIP-Seq_ESCs_Human1.03967256
115NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.03863046
116SUZ12_27294783_Chip-Seq_ESCs_Mouse1.02564990
117IGF1R_20145208_ChIP-Seq_DFB_Human1.02362796
118KDM2B_26808549_Chip-Seq_REH_Human1.01761166
119* TAL1_26923725_Chip-Seq_HPCs_Mouse1.01495877
120SCL_19346495_ChIP-Seq_HPC-7_Human1.01386571
121FLI1_21867929_ChIP-Seq_TH2_Mouse1.01307829
122SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.00605906
123POU3F1_26484290_ChIP-Seq_ESCss_Mouse1.00536842
124KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.99991697
125TCF4_22108803_ChIP-Seq_LS180_Human0.99956767
126SOX9_26525672_Chip-Seq_HEART_Mouse0.99210555
127RING1B_27294783_Chip-Seq_NPCs_Mouse0.99207595
128MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.97715611
129SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.95568867
130SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.94828691
131PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94483606
132SPI1_23547873_ChIP-Seq_NB4_Human0.91233709
133VDR_24787735_ChIP-Seq_THP-1_Human0.90354585
134PKCTHETA_26484144_Chip-Seq_BREAST_Human0.89735491
135IKZF1_21737484_ChIP-ChIP_HCT116_Human0.89603952
136OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.89398330
137MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.88124166
138SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.87874838
139SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.86876288
140MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.86222322
141ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.85925334
142POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.84617396
143TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84617396
144CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.84091607
145ZFP281_18757296_ChIP-ChIP_E14_Mouse0.83557088
146GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83112243
147SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.82719554
148LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82100201
149SMAD4_21799915_ChIP-Seq_A2780_Human0.81479533

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.80213399
2MP0000537_abnormal_urethra_morphology3.29187488
3MP0003121_genomic_imprinting3.02048873
4MP0000569_abnormal_digit_pigmentation2.95725568
5MP0003122_maternal_imprinting2.94890374
6MP0006292_abnormal_olfactory_placode2.74942561
7MP0002822_catalepsy2.57913647
8MP0001529_abnormal_vocalization2.42692591
9MP0008877_abnormal_DNA_methylation2.35693637
10MP0003195_calcinosis2.26940088
11MP0004134_abnormal_chest_morphology2.21952735
12MP0006276_abnormal_autonomic_nervous2.16122732
13MP0002938_white_spotting2.14614993
14MP0010234_abnormal_vibrissa_follicle2.14423510
15MP0006054_spinal_hemorrhage2.14341907
16MP0002736_abnormal_nociception_after2.02002886
17MP0003635_abnormal_synaptic_transmissio2.01453875
18MP0003942_abnormal_urinary_system1.97946742
19MP0005423_abnormal_somatic_nervous1.97338633
20MP0000778_abnormal_nervous_system1.95037953
21MP0004270_analgesia1.83893767
22MP0003385_abnormal_body_wall1.77450343
23MP0005257_abnormal_intraocular_pressure1.73212592
24MP0004133_heterotaxia1.70311311
25MP0008789_abnormal_olfactory_epithelium1.65143525
26MP0001486_abnormal_startle_reflex1.64563579
27MP0002184_abnormal_innervation1.61586585
28MP0005248_abnormal_Harderian_gland1.61165122
29MP0002063_abnormal_learning/memory/cond1.59253019
30MP0002272_abnormal_nervous_system1.57412914
31MP0009745_abnormal_behavioral_response1.52292986
32MP0005645_abnormal_hypothalamus_physiol1.51675755
33MP0002734_abnormal_mechanical_nocicepti1.51012865
34MP0004885_abnormal_endolymph1.48873836
35MP0004859_abnormal_synaptic_plasticity1.47896724
36MP0002572_abnormal_emotion/affect_behav1.47779809
37MP0005367_renal/urinary_system_phenotyp1.43299808
38MP0000516_abnormal_urinary_system1.43299808
39MP0005253_abnormal_eye_physiology1.43165538
40MP0005671_abnormal_response_to1.42024499
41MP0003787_abnormal_imprinting1.41995039
42MP0005551_abnormal_eye_electrophysiolog1.41330641
43MP0008058_abnormal_DNA_repair1.41099685
44MP0004142_abnormal_muscle_tone1.40716394
45MP0002928_abnormal_bile_duct1.39949675
46MP0002064_seizures1.39173574
47MP0002163_abnormal_gland_morphology1.38862112
48MP0002735_abnormal_chemical_nociception1.37001537
49MP0001915_intracranial_hemorrhage1.35955091
50MP0002102_abnormal_ear_morphology1.35396180
51MP0002752_abnormal_somatic_nervous1.31968517
52MP0009046_muscle_twitch1.31336938
53MP0003890_abnormal_embryonic-extraembry1.31025448
54MP0000631_abnormal_neuroendocrine_gland1.30565950
55MP0002882_abnormal_neuron_morphology1.30056669
56MP0001299_abnormal_eye_distance/1.27665430
57MP0002653_abnormal_ependyma_morphology1.27149735
58MP0005646_abnormal_pituitary_gland1.27015875
59MP0002067_abnormal_sensory_capabilities1.26970681
60MP0002282_abnormal_trachea_morphology1.25888921
61MP0002751_abnormal_autonomic_nervous1.25723353
62MP0003315_abnormal_perineum_morphology1.24979175
63MP0003567_abnormal_fetal_cardiomyocyte1.23112046
64MP0001502_abnormal_circadian_rhythm1.22682488
65MP0003755_abnormal_palate_morphology1.21258514
66MP0001968_abnormal_touch/_nociception1.19007687
67MP0010094_abnormal_chromosome_stability1.16639533
68MP0001984_abnormal_olfaction1.16170535
69MP0008007_abnormal_cellular_replicative1.15364214
70MP0003861_abnormal_nervous_system1.15285864
71MP0000428_abnormal_craniofacial_morphol1.14354089
72MP0005076_abnormal_cell_differentiation1.14028412
73MP0001835_abnormal_antigen_presentation1.14012970
74MP0001485_abnormal_pinna_reflex1.13340544
75MP0001905_abnormal_dopamine_level1.13208606
76MP0005386_behavior/neurological_phenoty1.12963191
77MP0004924_abnormal_behavior1.12963191
78MP0000566_synostosis1.12730046
79MP0010030_abnormal_orbit_morphology1.12257071
80MP0005187_abnormal_penis_morphology1.10938396
81MP0002116_abnormal_craniofacial_bone1.10202339
82MP0001970_abnormal_pain_threshold1.08894080
83MP0003937_abnormal_limbs/digits/tail_de1.08278517
84MP0002160_abnormal_reproductive_system1.07898585
85MP0006082_CNS_inflammation1.07436894
86MP0002837_dystrophic_cardiac_calcinosis1.06560964
87MP0005499_abnormal_olfactory_system1.06419453
88MP0005394_taste/olfaction_phenotype1.06419453
89MP0000733_abnormal_muscle_development1.04835207
90MP0002638_abnormal_pupillary_reflex1.04240310
91MP0004808_abnormal_hematopoietic_stem1.02497349
92MP0003938_abnormal_ear_development1.02004577
93MP0005195_abnormal_posterior_eye1.01290038
94MP0008961_abnormal_basal_metabolism1.01210481
95MP0005409_darkened_coat_color1.01184426
96MP0004811_abnormal_neuron_physiology0.98850442
97MP0008057_abnormal_DNA_replication0.98012826
98MP0002733_abnormal_thermal_nociception0.97192328
99MP0010368_abnormal_lymphatic_system0.96251885
100MP0005391_vision/eye_phenotype0.94767292
101MP0003943_abnormal_hepatobiliary_system0.93670278
102MP0001286_abnormal_eye_development0.91417583
103MP0008260_abnormal_autophagy0.90598795
104MP0003119_abnormal_digestive_system0.89915130
105MP0003436_decreased_susceptibility_to0.89407551
106MP0009250_abnormal_appendicular_skeleto0.89005121
107MP0006072_abnormal_retinal_apoptosis0.88837105
108MP0003136_yellow_coat_color0.87880367
109MP0000955_abnormal_spinal_cord0.86620316
110MP0003935_abnormal_craniofacial_develop0.85219626
111MP0003303_peritoneal_inflammation0.84842081
112MP0002557_abnormal_social/conspecific_i0.84740296
113MP0000049_abnormal_middle_ear0.84198240
114MP0001879_abnormal_lymphatic_vessel0.83272601
115MP0003077_abnormal_cell_cycle0.83151472
116MP0001177_atelectasis0.82471837
117MP0009703_decreased_birth_body0.82307173
118MP0005000_abnormal_immune_tolerance0.81953710
119MP0002877_abnormal_melanocyte_morpholog0.81476824
120MP0001270_distended_abdomen0.81415086
121MP0000026_abnormal_inner_ear0.81089823
122MP0001293_anophthalmia0.80719330
123MP0002234_abnormal_pharynx_morphology0.80536029
124MP0005171_absent_coat_pigmentation0.79728387
125MP0005379_endocrine/exocrine_gland_phen0.79340458
126MP0002066_abnormal_motor_capabilities/c0.79196127
127MP0002095_abnormal_skin_pigmentation0.78710455
128MP0003123_paternal_imprinting0.77803682
129MP0002177_abnormal_outer_ear0.76913217
130MP0001188_hyperpigmentation0.76803517
131MP0001963_abnormal_hearing_physiology0.76647075
132MP0001849_ear_inflammation0.76620136
133MP0003283_abnormal_digestive_organ0.76570010
134MP0003115_abnormal_respiratory_system0.76187092
135MP0002081_perinatal_lethality0.75822768
136MP0002152_abnormal_brain_morphology0.75798270
137MP0010386_abnormal_urinary_bladder0.75692160
138MP0000534_abnormal_ureter_morphology0.75465137
139MP0002148_abnormal_hypersensitivity_rea0.75218505
140MP0005174_abnormal_tail_pigmentation0.75026208
141MP0000015_abnormal_ear_pigmentation0.75020747
142MP0005197_abnormal_uvea_morphology0.74913609
143MP0002233_abnormal_nose_morphology0.74713746
144MP0003698_abnormal_male_reproductive0.74452076
145MP0000767_abnormal_smooth_muscle0.74177217
146MP0000432_abnormal_head_morphology0.72465524
147MP0008932_abnormal_embryonic_tissue0.72300456

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.46381532
2Aqueductal stenosis (HP:0002410)3.39885920
3Increased nuchal translucency (HP:0010880)3.29835979
4Abnormality of midbrain morphology (HP:0002418)3.28722184
5Molar tooth sign on MRI (HP:0002419)3.28722184
6Proximal placement of thumb (HP:0009623)3.14612432
7Nephronophthisis (HP:0000090)3.02086004
8Deviation of the thumb (HP:0009603)2.89642951
9Focal motor seizures (HP:0011153)2.89143159
10Subacute progressive viral hepatitis (HP:0006572)2.84178048
11Drooling (HP:0002307)2.81436892
12Large earlobe (HP:0009748)2.81378003
13Hyperacusis (HP:0010780)2.80605171
14Gait imbalance (HP:0002141)2.71613160
15High anterior hairline (HP:0009890)2.70852974
16Postaxial hand polydactyly (HP:0001162)2.70350830
17Focal seizures (HP:0007359)2.65186640
18Abnormal respiratory motile cilium morphology (HP:0005938)2.63708614
19Abnormal respiratory epithelium morphology (HP:0012253)2.63708614
20True hermaphroditism (HP:0010459)2.63237920
21Excessive salivation (HP:0003781)2.58126298
22Abnormal ciliary motility (HP:0012262)2.57472291
23Absent speech (HP:0001344)2.49583284
24Esophageal atresia (HP:0002032)2.48139245
25Febrile seizures (HP:0002373)2.46055770
26Abnormality of the renal medulla (HP:0100957)2.45594210
27Renal duplication (HP:0000075)2.44984023
28Retinal dysplasia (HP:0007973)2.44199819
29Abnormality of the fetal cardiovascular system (HP:0010948)2.39997118
30Abnormal umbilical cord blood vessels (HP:0011403)2.39997118
31Single umbilical artery (HP:0001195)2.39997118
32Morphological abnormality of the middle ear (HP:0008609)2.39083397
33Meckel diverticulum (HP:0002245)2.37283560
34Abnormality of the labia minora (HP:0012880)2.37222660
35Congenital primary aphakia (HP:0007707)2.34644644
36Cystic liver disease (HP:0006706)2.32064014
37Pancreatic fibrosis (HP:0100732)2.28841642
38Supernumerary spleens (HP:0009799)2.28333307
39Hyperventilation (HP:0002883)2.27820085
40Absent/shortened dynein arms (HP:0200106)2.26680501
41Dynein arm defect of respiratory motile cilia (HP:0012255)2.26680501
42Abnormal respiratory motile cilium physiology (HP:0012261)2.25015758
43Progressive cerebellar ataxia (HP:0002073)2.23912293
44Aplasia/Hypoplasia of the uvula (HP:0010293)2.23048128
45Trigonocephaly (HP:0000243)2.22075689
46Specific learning disability (HP:0001328)2.21599961
47Polyphagia (HP:0002591)2.20769142
48Abnormality of the ileum (HP:0001549)2.19799114
49Large eyes (HP:0001090)2.18803054
50Severe Myopia (HP:0011003)2.17436669
51Atonic seizures (HP:0010819)2.17338669
52Elfin facies (HP:0004428)2.14928064
53Bowel diverticulosis (HP:0005222)2.13847155
54Hemiparesis (HP:0001269)2.13466435
55Narrow forehead (HP:0000341)2.13172388
56Occipital encephalocele (HP:0002085)2.11517701
57Lissencephaly (HP:0001339)2.10912152
58Male pseudohermaphroditism (HP:0000037)2.09088446
59Broad foot (HP:0001769)2.08572759
60Amyotrophic lateral sclerosis (HP:0007354)2.08191624
61Optic nerve hypoplasia (HP:0000609)2.07846965
62Obsessive-compulsive behavior (HP:0000722)2.07655781
63Absent radius (HP:0003974)2.05449354
64Germ cell neoplasia (HP:0100728)2.05178734
65Medial flaring of the eyebrow (HP:0010747)2.04995526
66Gastrointestinal atresia (HP:0002589)2.04733169
67Nephrogenic diabetes insipidus (HP:0009806)2.04613044
68Short foot (HP:0001773)2.03893378
69Hypoplasia of the pons (HP:0012110)2.03551012
70Papilledema (HP:0001085)2.02804833
71Preaxial hand polydactyly (HP:0001177)2.02123419
72Hypothermia (HP:0002045)2.00938538
73Midline defect of the nose (HP:0004122)2.00880158
74Congenital hepatic fibrosis (HP:0002612)2.00636356
75Abnormality of the aortic arch (HP:0012303)2.00577741
76Sclerocornea (HP:0000647)2.00080444
77Abnormality of the carotid arteries (HP:0005344)1.99391574
78Pachygyria (HP:0001302)1.98848338
79Viral hepatitis (HP:0006562)1.98282080
80Neoplasm of the adrenal cortex (HP:0100641)1.98044426
81Median cleft lip (HP:0000161)1.96335424
82Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.96072371
83Vaginal atresia (HP:0000148)1.95976971
84Urethral obstruction (HP:0000796)1.95387314
85Abnormal drinking behavior (HP:0030082)1.94470667
86Polydipsia (HP:0001959)1.94470667
87Myokymia (HP:0002411)1.94047883
88Aplasia/Hypoplasia of the sternum (HP:0006714)1.93194156
89Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.92320884
90Aplasia involving forearm bones (HP:0009822)1.92077464
91Absent forearm bone (HP:0003953)1.92077464
92Genital tract atresia (HP:0001827)1.91621177
93Chromosomal breakage induced by crosslinking agents (HP:0003221)1.91401663
94Recurrent abscess formation (HP:0002722)1.91047815
95Limb dystonia (HP:0002451)1.90326421
96Abnormality of chromosome stability (HP:0003220)1.89957183
97Chronic hepatic failure (HP:0100626)1.89139225
98Tented upper lip vermilion (HP:0010804)1.88515527
99Abnormal sex determination (HP:0012244)1.87730422
100Sex reversal (HP:0012245)1.87730422
101Poor coordination (HP:0002370)1.87703098
102Abnormality of the corticospinal tract (HP:0002492)1.87342460
103Abnormality of the duodenum (HP:0002246)1.86474423
104Small intestinal stenosis (HP:0012848)1.86293020
105Duodenal stenosis (HP:0100867)1.86293020
106Wrist flexion contracture (HP:0001239)1.85372072
107Low anterior hairline (HP:0000294)1.85288003
108Anencephaly (HP:0002323)1.85234958
109Protruding tongue (HP:0010808)1.85115900
110Oligodactyly (hands) (HP:0001180)1.83944552
111Abnormality of the pubic bones (HP:0003172)1.83910721
112Intestinal atresia (HP:0011100)1.83639543
113Cutaneous syndactyly (HP:0012725)1.83555920
114Tubulointerstitial nephritis (HP:0001970)1.83372761
115Dental crowding (HP:0000678)1.82421268
116Optic nerve coloboma (HP:0000588)1.81964932
117Aplasia/Hypoplasia of the tongue (HP:0010295)1.81641212
118Cutaneous finger syndactyly (HP:0010554)1.81050282
119Broad-based gait (HP:0002136)1.81000089
120Agnosia (HP:0010524)1.80904293
121Type II lissencephaly (HP:0007260)1.79852933
122Hypoplastic iliac wings (HP:0002866)1.78196319
123Micropenis (HP:0000054)1.77748430
124Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.77359807
125Ectopic kidney (HP:0000086)1.77286702
126Flat cornea (HP:0007720)1.76909729
127Shallow orbits (HP:0000586)1.76232411
128Anophthalmia (HP:0000528)1.75993363
129Overriding aorta (HP:0002623)1.75846178
130Vitreoretinal degeneration (HP:0000655)1.75098465
131Abnormality of the preputium (HP:0100587)1.74005365
132Abnormality of DNA repair (HP:0003254)1.73972303
133Hyperglycinemia (HP:0002154)1.73689646
134Congenital stationary night blindness (HP:0007642)1.72945930
135Shawl scrotum (HP:0000049)1.72730390
136Pancreatic cysts (HP:0001737)1.72282721
137Renovascular hypertension (HP:0100817)1.72265943
138Holoprosencephaly (HP:0001360)1.72183811
139Renal dysplasia (HP:0000110)1.72092716
140Aganglionic megacolon (HP:0002251)1.71954856
141Cutis marmorata (HP:0000965)1.71932060
142Nephroblastoma (Wilms tumor) (HP:0002667)1.71519323
143Amblyopia (HP:0000646)1.70768070
144Adrenal hypoplasia (HP:0000835)1.69330929
145Abnormality of the phalanges of the hallux (HP:0010057)1.69154586
146Hypomagnesemia (HP:0002917)1.68975710
147Intestinal fistula (HP:0100819)1.68771964
148Short philtrum (HP:0000322)1.67952085
149Bilateral microphthalmos (HP:0007633)1.67861844
150Rhinitis (HP:0012384)1.67825282
151Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.67676473
152Short 4th metacarpal (HP:0010044)1.67676473
153Abnormality of the renal cortex (HP:0011035)1.67459150
154Dialeptic seizures (HP:0011146)1.67157228
155Abdominal situs inversus (HP:0003363)1.67076768
156Abnormality of abdominal situs (HP:0011620)1.67076768
157Abnormal number of incisors (HP:0011064)1.66854761
158Abnormality of salivation (HP:0100755)1.66744772
159Clubbing of toes (HP:0100760)1.66584907
160Thyroiditis (HP:0100646)1.66171436
161Aplasia/Hypoplasia of the lens (HP:0008063)1.64881302
162Heterochromia iridis (HP:0001100)1.64224745
163Round face (HP:0000311)1.63381503
164Postaxial foot polydactyly (HP:0001830)1.62420161
165Breast carcinoma (HP:0003002)1.61889623
166Colon cancer (HP:0003003)1.61588387
167Triphalangeal thumb (HP:0001199)1.61264134
168Duplication of thumb phalanx (HP:0009942)1.60781925
169Embryonal renal neoplasm (HP:0011794)1.59756773
170Agitation (HP:0000713)1.58562787
171Hepatoblastoma (HP:0002884)1.58471509
172Rectovaginal fistula (HP:0000143)1.57980175
173Rectal fistula (HP:0100590)1.57980175
174Striae distensae (HP:0001065)1.57286573
175Renal hypoplasia (HP:0000089)1.57268618

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.63929217
2NTRK23.79129386
3MAPK133.35103439
4MAPKAPK33.17681174
5PINK12.97903936
6WNK32.78430266
7MARK12.71463988
8TGFBR22.49752209
9EPHA42.44831183
10ERBB32.43756046
11MAP3K122.35010267
12PAK42.14261052
13SIK22.05709756
14CSNK1A1L2.01095999
15TAOK21.88071892
16CSNK1G31.85081107
17NEK11.79870712
18INSRR1.73447116
19MAPKAPK51.71408844
20TRIM281.69768712
21TLK11.65538927
22MAP4K21.64800790
23NTRK31.63071620
24TRPM71.62207704
25ACVR1B1.60770191
26DYRK21.59003861
27PRPF4B1.54313945
28SGK2231.48832187
29SGK4941.48832187
30EPHB21.47338273
31ZAK1.45692562
32MKNK11.44198702
33SGK21.44103305
34SRPK11.39565787
35UHMK11.34034362
36ADRBK21.32416266
37YES11.23924694
38KIT1.23858148
39CSNK1G21.23677950
40EIF2AK21.23641488
41MKNK21.22194446
42GRK71.19001908
43CDK61.13533516
44CSF1R1.12400056
45CSNK1G11.11463776
46PRKCG1.10862734
47PNCK1.04324925
48CDK31.03565042
49CAMK1G1.01682128
50MAP2K40.96825407
51TGFBR10.96752473
52NLK0.95091542
53MAPK150.94200844
54CLK10.93622937
55DYRK30.91531118
56EPHA30.90961538
57DYRK1A0.90729133
58LIMK10.90425458
59TNIK0.90090177
60ERBB20.90025462
61PTK60.89378821
62FER0.88469312
63TXK0.87638696
64GRK10.86809818
65RPS6KB20.86410724
66CHUK0.83221816
67PRKCE0.82555252
68PRKD30.82423741
69FGFR20.80736606
70MARK30.80512463
71ATR0.79327569
72RPS6KA20.75537162
73LATS10.73852991
74STK38L0.72881213
75DYRK1B0.72546748
76IRAK20.71212285
77MAP3K90.70309094
78STK30.69857559
79IKBKE0.69415634
80CASK0.68531149
81MAP3K110.66152005
82SGK30.66004222
83SIK30.64846333
84BMPR1B0.64666295
85PASK0.64166997
86CAMK40.64144578
87PKN20.64023361
88BTK0.63948929
89DAPK20.62665440
90MAP3K70.61989492
91TYK20.61488250
92BLK0.60995602
93KSR10.60794024
94NUAK10.60132454
95IRAK40.59858534
96PRKCQ0.59269007
97STK110.59048324
98BCKDK0.58554202
99FRK0.58508902
100MAP2K70.58446910
101SGK10.58092177
102BRD40.57578692
103TESK20.57534179
104CAMK1D0.57444872
105PAK60.57154543
106PRKCZ0.55876883
107BCR0.55321091
108MINK10.55058313
109PIK3CA0.53408103
110PAK30.52782343
111NEK20.52676820
112MOS0.52637134
113TBK10.52393953
114CSNK1D0.51430869
115FLT30.51292710
116TIE10.50952602
117CAMK2A0.50533180
118TYRO30.50405143
119ITK0.49910129
120RPS6KB10.49647959
121CSNK1A10.49498568
122PLK20.48614796
123CAMKK20.48232982
124PKN10.48044384
125OBSCN0.48019948
126IRAK10.47627888
127MARK20.47541365
128ATM0.47288563
129MAP3K130.46061273
130MAP3K140.46026920
131PHKG20.45803599
132PHKG10.45803599
133STK160.45683213
134TTK0.45581937
135CDK50.44049583
136BMPR20.43472563
137ADRBK10.43422402
138PRKG10.43087426
139MAP3K40.41840880
140WNK40.41438169
141CDK140.41397975
142VRK10.38981342
143CDC42BPA0.38277432
144ICK0.37095659
145MAPK120.35926695
146PRKACA0.35590285
147LCK0.34968742
148DAPK10.34187126
149FGFR30.33580641
150CAMK10.33170564
151RIPK40.32663940
152CDK190.32123947
153PRKCH0.32084739
154CAMK2B0.30879288
155CAMKK10.30505788
156FGFR10.28712662
157STK390.27969220

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.93924723
2Butanoate metabolism_Homo sapiens_hsa006502.36276118
3GABAergic synapse_Homo sapiens_hsa047272.08952175
4Phototransduction_Homo sapiens_hsa047441.97727484
5Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.95819005
6Fanconi anemia pathway_Homo sapiens_hsa034601.91725876
7Steroid biosynthesis_Homo sapiens_hsa001001.88753427
8Taste transduction_Homo sapiens_hsa047421.73089950
9Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.70257111
10Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.70092651
11Glutamatergic synapse_Homo sapiens_hsa047241.69250431
12Cocaine addiction_Homo sapiens_hsa050301.67468308
13Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.64874722
14Propanoate metabolism_Homo sapiens_hsa006401.61992397
15Non-homologous end-joining_Homo sapiens_hsa034501.60399818
16DNA replication_Homo sapiens_hsa030301.60200373
17Insulin secretion_Homo sapiens_hsa049111.59238303
18Mismatch repair_Homo sapiens_hsa034301.58810986
19Colorectal cancer_Homo sapiens_hsa052101.56536984
20Regulation of autophagy_Homo sapiens_hsa041401.55115078
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.51240719
22Axon guidance_Homo sapiens_hsa043601.50628820
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.48330684
24Base excision repair_Homo sapiens_hsa034101.44741991
25Amphetamine addiction_Homo sapiens_hsa050311.41850137
26Spliceosome_Homo sapiens_hsa030401.37092034
27Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.35624338
28Long-term depression_Homo sapiens_hsa047301.30633712
29Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.25993190
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.25724304
31Toll-like receptor signaling pathway_Homo sapiens_hsa046201.24982579
32Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.23558681
33Leishmaniasis_Homo sapiens_hsa051401.23425379
34Glycosaminoglycan degradation_Homo sapiens_hsa005311.18758789
35Cell cycle_Homo sapiens_hsa041101.18142586
36Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.12051867
37Viral myocarditis_Homo sapiens_hsa054161.09744286
38Endometrial cancer_Homo sapiens_hsa052131.09535187
39Notch signaling pathway_Homo sapiens_hsa043301.09513232
40Basal cell carcinoma_Homo sapiens_hsa052171.08599714
41Primary immunodeficiency_Homo sapiens_hsa053401.06302783
42Salivary secretion_Homo sapiens_hsa049701.05894760
43Transcriptional misregulation in cancer_Homo sapiens_hsa052021.04158278
44Oxytocin signaling pathway_Homo sapiens_hsa049211.03037553
45Circadian entrainment_Homo sapiens_hsa047131.02470846
46Nicotine addiction_Homo sapiens_hsa050331.02233506
47Basal transcription factors_Homo sapiens_hsa030221.01557969
48Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00484199
49Measles_Homo sapiens_hsa051620.99384488
50NF-kappa B signaling pathway_Homo sapiens_hsa040640.98000124
51Dorso-ventral axis formation_Homo sapiens_hsa043200.97935195
52B cell receptor signaling pathway_Homo sapiens_hsa046620.97352679
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.94653365
54Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.94413437
55Protein export_Homo sapiens_hsa030600.94194930
56Thyroid cancer_Homo sapiens_hsa052160.94144879
57Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.94091682
58HTLV-I infection_Homo sapiens_hsa051660.93969583
59Pertussis_Homo sapiens_hsa051330.93968995
60MicroRNAs in cancer_Homo sapiens_hsa052060.93503880
61Morphine addiction_Homo sapiens_hsa050320.92307435
62Intestinal immune network for IgA production_Homo sapiens_hsa046720.91851511
63Nitrogen metabolism_Homo sapiens_hsa009100.91511340
64Osteoclast differentiation_Homo sapiens_hsa043800.91459941
65Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.91296922
66Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.91087739
67Allograft rejection_Homo sapiens_hsa053300.90930316
68Gastric acid secretion_Homo sapiens_hsa049710.90647772
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.90402609
70Adherens junction_Homo sapiens_hsa045200.89826096
71Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.89674570
72Chemokine signaling pathway_Homo sapiens_hsa040620.88849965
73Gap junction_Homo sapiens_hsa045400.88233183
74Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.88157784
75cAMP signaling pathway_Homo sapiens_hsa040240.87329229
76Chronic myeloid leukemia_Homo sapiens_hsa052200.87232468
77Herpes simplex infection_Homo sapiens_hsa051680.86304285
78Hepatitis B_Homo sapiens_hsa051610.84882133
79Serotonergic synapse_Homo sapiens_hsa047260.84383089
80Circadian rhythm_Homo sapiens_hsa047100.84335780
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.83506606
82Prion diseases_Homo sapiens_hsa050200.83387974
83TGF-beta signaling pathway_Homo sapiens_hsa043500.82094588
84Calcium signaling pathway_Homo sapiens_hsa040200.81917447
85African trypanosomiasis_Homo sapiens_hsa051430.81416825
86Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.80340597
87Hematopoietic cell lineage_Homo sapiens_hsa046400.80000256
88Renin secretion_Homo sapiens_hsa049240.79885196
89T cell receptor signaling pathway_Homo sapiens_hsa046600.79676442
90Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79603469
91mRNA surveillance pathway_Homo sapiens_hsa030150.78668363
92Homologous recombination_Homo sapiens_hsa034400.78333064
93Type II diabetes mellitus_Homo sapiens_hsa049300.78185472
94Influenza A_Homo sapiens_hsa051640.77289968
95Oocyte meiosis_Homo sapiens_hsa041140.76320513
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.76286908
97Salmonella infection_Homo sapiens_hsa051320.76120914
98Rap1 signaling pathway_Homo sapiens_hsa040150.75278160
99Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75257600
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.74767651
101Hippo signaling pathway_Homo sapiens_hsa043900.74754484
102Peroxisome_Homo sapiens_hsa041460.73841902
103Aldosterone synthesis and secretion_Homo sapiens_hsa049250.72477609
104Olfactory transduction_Homo sapiens_hsa047400.72433487
105Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.72309450
106Wnt signaling pathway_Homo sapiens_hsa043100.72008107
107Ether lipid metabolism_Homo sapiens_hsa005650.71584326
108Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71270362
109Nucleotide excision repair_Homo sapiens_hsa034200.70802525
110ErbB signaling pathway_Homo sapiens_hsa040120.70697544
111Pancreatic cancer_Homo sapiens_hsa052120.70662997
112Ras signaling pathway_Homo sapiens_hsa040140.70490890
113Legionellosis_Homo sapiens_hsa051340.70251380
114Alcoholism_Homo sapiens_hsa050340.70194689
115cGMP-PKG signaling pathway_Homo sapiens_hsa040220.69973157
116Synaptic vesicle cycle_Homo sapiens_hsa047210.69056431
117Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.68881440
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.68596702
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.68252413
120Tuberculosis_Homo sapiens_hsa051520.67910879
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.67516197
122Glioma_Homo sapiens_hsa052140.67258176
123Melanoma_Homo sapiens_hsa052180.66998269
124Epstein-Barr virus infection_Homo sapiens_hsa051690.66857872
125Prostate cancer_Homo sapiens_hsa052150.66771852
126Phagosome_Homo sapiens_hsa041450.66440898
127Pathways in cancer_Homo sapiens_hsa052000.65497114
128Hedgehog signaling pathway_Homo sapiens_hsa043400.65307448
129RNA degradation_Homo sapiens_hsa030180.64692191
130Shigellosis_Homo sapiens_hsa051310.64573381
131Dopaminergic synapse_Homo sapiens_hsa047280.62815852
132Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.62651858
133Inositol phosphate metabolism_Homo sapiens_hsa005620.62181618
134Melanogenesis_Homo sapiens_hsa049160.61826049
135Toxoplasmosis_Homo sapiens_hsa051450.61814684
136Malaria_Homo sapiens_hsa051440.61333993
137Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.60846468
138Antigen processing and presentation_Homo sapiens_hsa046120.60781144
139Apoptosis_Homo sapiens_hsa042100.60232821
140Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.60097621
141Cholinergic synapse_Homo sapiens_hsa047250.59924738
142Asthma_Homo sapiens_hsa053100.59877760
143Graft-versus-host disease_Homo sapiens_hsa053320.59440430
144Lysine degradation_Homo sapiens_hsa003100.57291595
145MAPK signaling pathway_Homo sapiens_hsa040100.57155832
146Choline metabolism in cancer_Homo sapiens_hsa052310.56836897
147Cardiac muscle contraction_Homo sapiens_hsa042600.55991940
148Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.55336277
149Long-term potentiation_Homo sapiens_hsa047200.54584338
150Dilated cardiomyopathy_Homo sapiens_hsa054140.54500627
151Linoleic acid metabolism_Homo sapiens_hsa005910.53298341
152Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52497042
153Fatty acid metabolism_Homo sapiens_hsa012120.50823716
154Vascular smooth muscle contraction_Homo sapiens_hsa042700.50047004
155beta-Alanine metabolism_Homo sapiens_hsa004100.49733259
156ABC transporters_Homo sapiens_hsa020100.49263538
157Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.48639204
158FoxO signaling pathway_Homo sapiens_hsa040680.47693886
159mTOR signaling pathway_Homo sapiens_hsa041500.47482722
160alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46000081
161Glycerolipid metabolism_Homo sapiens_hsa005610.43907293
162Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.43760271
163Glycerophospholipid metabolism_Homo sapiens_hsa005640.43721890

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »