ZG16

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal epithelial cell development (GO:0060576)9.65838450
2intestinal cholesterol absorption (GO:0030299)9.50023049
3intestinal absorption (GO:0050892)8.63623786
4low-density lipoprotein particle remodeling (GO:0034374)8.33065980
5lung secretory cell differentiation (GO:0061140)8.29923978
6digestion (GO:0007586)7.67573829
7regulation of guanylate cyclase activity (GO:0031282)7.46433000
8bile acid and bile salt transport (GO:0015721)7.35444795
9regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)7.23019872
10maintenance of gastrointestinal epithelium (GO:0030277)6.21661096
11sulfation (GO:0051923)6.07431323
12hepatocyte apoptotic process (GO:0097284)6.00238996
13glandular epithelial cell differentiation (GO:0002067)5.94455038
14phosphatidylinositol acyl-chain remodeling (GO:0036149)5.92398274
15positive regulation of macrophage derived foam cell differentiation (GO:0010744)5.87212837
16positive regulation of guanylate cyclase activity (GO:0031284)5.69691071
17epoxygenase P450 pathway (GO:0019373)5.67592878
18NADH metabolic process (GO:0006734)5.65635362
19cellular glucuronidation (GO:0052695)5.62723007
20phosphatidylserine acyl-chain remodeling (GO:0036150)5.62694099
21UDP-N-acetylglucosamine metabolic process (GO:0006047)5.53180701
22sulfate transmembrane transport (GO:1902358)5.52834254
23calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)5.51011088
24glucuronate metabolic process (GO:0019585)5.49166266
25uronic acid metabolic process (GO:0006063)5.49166266
26digestive system process (GO:0022600)5.44825011
27lipoprotein transport (GO:0042953)5.32209627
28regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.24963697
29endocrine process (GO:0050886)5.24963697
30regulation of systemic arterial blood pressure by hormone (GO:0001990)5.24963697
31proline biosynthetic process (GO:0006561)5.15206481
32fat-soluble vitamin biosynthetic process (GO:0042362)5.13959194
33regulation of glucose import in response to insulin stimulus (GO:2001273)5.12125576
34phosphatidylglycerol acyl-chain remodeling (GO:0036148)5.04108882
35positive regulation of respiratory burst (GO:0060267)4.85133333
36renal system process involved in regulation of blood volume (GO:0001977)4.83663524
37receptor guanylyl cyclase signaling pathway (GO:0007168)4.75712743
38regulation of systemic arterial blood pressure (GO:0003073)4.63304007
39regulation of cGMP biosynthetic process (GO:0030826)4.63092005
40epithelial structure maintenance (GO:0010669)4.59130444
41O-glycan processing (GO:0016266)4.54884521
42sulfate transport (GO:0008272)4.51582022
43galactose catabolic process (GO:0019388)4.50817697
44positive regulation of cellular response to insulin stimulus (GO:1900078)4.42961703
45positive regulation of pseudopodium assembly (GO:0031274)4.41278169
46phosphatidylserine metabolic process (GO:0006658)4.41220300
47plasma lipoprotein particle remodeling (GO:0034369)4.37458979
48protein-lipid complex remodeling (GO:0034368)4.37458979
49macromolecular complex remodeling (GO:0034367)4.37458979
50hormone catabolic process (GO:0042447)4.36984319
51regulation of vitamin metabolic process (GO:0030656)4.30484726
52drug metabolic process (GO:0017144)4.29982860
53exocrine pancreas development (GO:0031017)4.27880427
54transcytosis (GO:0045056)4.23564560
55primary alcohol catabolic process (GO:0034310)4.23143265
56pyrimidine-containing compound transmembrane transport (GO:0072531)4.22780777
57galactose metabolic process (GO:0006012)4.19438359
58phosphatidylethanolamine acyl-chain remodeling (GO:0036152)4.19260414
59ethanol metabolic process (GO:0006067)4.16619177
60negative regulation of cell fate commitment (GO:0010454)4.15095414
61regulation of norepinephrine secretion (GO:0014061)4.11714912
62bundle of His cell to Purkinje myocyte communication (GO:0086069)4.11486933
63GDP-mannose metabolic process (GO:0019673)4.08208832
64antibacterial humoral response (GO:0019731)4.06871005
65fructose metabolic process (GO:0006000)4.02593160
66protein retention in ER lumen (GO:0006621)3.97757179
67urea cycle (GO:0000050)3.96798744
68regulation of pseudopodium assembly (GO:0031272)3.94789494
69antimicrobial humoral response (GO:0019730)3.91514127
70bile acid metabolic process (GO:0008206)3.89423959
71negative regulation of epidermal cell differentiation (GO:0045605)3.89153457
72oligosaccharide biosynthetic process (GO:0009312)3.87689628
73negative regulation of keratinocyte proliferation (GO:0010839)3.85938141
74regulation of cGMP metabolic process (GO:0030823)3.85140611
75urea metabolic process (GO:0019627)3.78803513
76cysteine metabolic process (GO:0006534)3.78497166
77maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.76239914
78regulation of triglyceride catabolic process (GO:0010896)3.73155428
79glomerular filtration (GO:0003094)3.69583890
80ethanol oxidation (GO:0006069)3.67535874
81adhesion of symbiont to host cell (GO:0044650)3.66802616
82virion attachment to host cell (GO:0019062)3.66802616
83mucosal immune response (GO:0002385)3.66619071
84positive regulation of glycoprotein biosynthetic process (GO:0010560)3.64686971
85lung epithelial cell differentiation (GO:0060487)3.63342501
86very-low-density lipoprotein particle assembly (GO:0034379)3.62813288
87lung cell differentiation (GO:0060479)3.62226826
88sulfur amino acid catabolic process (GO:0000098)3.62206201
89regulation of respiratory burst (GO:0060263)3.60860925
90alditol phosphate metabolic process (GO:0052646)3.59487955
91nucleoside diphosphate biosynthetic process (GO:0009133)3.58286630
92regulation of bile acid biosynthetic process (GO:0070857)3.56599651
93mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.54701121
94plasma lipoprotein particle organization (GO:0071827)3.54643573
95regulation of cholesterol homeostasis (GO:2000188)3.52737487
96cobalamin metabolic process (GO:0009235)3.52311722
97sulfur compound transport (GO:0072348)3.52253041
98proline metabolic process (GO:0006560)3.51978163
99protein-lipid complex subunit organization (GO:0071825)3.51662207
100glycosphingolipid catabolic process (GO:0046479)3.51428676
101fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.51087009
102glycolipid catabolic process (GO:0019377)3.49404839
103peptide hormone processing (GO:0016486)3.48999358
104renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.48878139
105nitrogen cycle metabolic process (GO:0071941)3.46376001
106regulation of keratinocyte proliferation (GO:0010837)3.45685256
107organ or tissue specific immune response (GO:0002251)3.45676478
108positive regulation of epidermal cell differentiation (GO:0045606)3.42587911
109positive regulation of fatty acid beta-oxidation (GO:0032000)3.41750823
110glucocorticoid biosynthetic process (GO:0006704)3.41297783
111plasma lipoprotein particle assembly (GO:0034377)3.40019521
112cGMP-mediated signaling (GO:0019934)3.39881493
113tumor necrosis factor-mediated signaling pathway (GO:0033209)3.39602411
114vitamin transmembrane transport (GO:0035461)3.39392114
115positive regulation of cGMP biosynthetic process (GO:0030828)3.39341882
116thrombin receptor signaling pathway (GO:0070493)3.39340491
117phosphatidylcholine acyl-chain remodeling (GO:0036151)3.38934020
118purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.38216925
1193-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.38216925
120regulation of macrophage derived foam cell differentiation (GO:0010743)3.38108950
121drug transport (GO:0015893)3.38056791
122drug transmembrane transport (GO:0006855)3.37418933
123renal filtration (GO:0097205)3.34360648
124drug catabolic process (GO:0042737)3.30973615
125positive regulation of lipid catabolic process (GO:0050996)3.30654231
126sphingomyelin metabolic process (GO:0006684)3.30161745
127positive regulation of glycoprotein metabolic process (GO:1903020)3.29691075
128regulation of viral entry into host cell (GO:0046596)3.22619937
129alkaloid metabolic process (GO:0009820)3.21031154
130arginine metabolic process (GO:0006525)3.20692038
131leukotriene biosynthetic process (GO:0019370)3.20306480
132cGMP biosynthetic process (GO:0006182)3.18299229
133glycosylceramide metabolic process (GO:0006677)3.17615592
134N-acetylglucosamine metabolic process (GO:0006044)3.16076700
135columnar/cuboidal epithelial cell development (GO:0002066)3.15490334
136nucleotide-sugar metabolic process (GO:0009225)3.14626786
137phospholipid efflux (GO:0033700)3.14166428
138diacylglycerol metabolic process (GO:0046339)3.13165484
139sodium ion homeostasis (GO:0055078)3.11782983
140protein-lipid complex assembly (GO:0065005)3.10840489
141endocrine pancreas development (GO:0031018)3.10820333
142exogenous drug catabolic process (GO:0042738)3.10461230
143adhesion of symbiont to host (GO:0044406)3.09938603
144regulation of hydrogen peroxide metabolic process (GO:0010310)3.09747774
145regulation of cellular extravasation (GO:0002691)3.09358885
146auditory receptor cell differentiation (GO:0042491)3.08643264
147peptide catabolic process (GO:0043171)3.08308798
148phosphatidic acid metabolic process (GO:0046473)3.07764378
149phosphatidic acid biosynthetic process (GO:0006654)3.07764378
150angiotensin maturation (GO:0002003)3.07269783
151energy coupled proton transport, down electrochemical gradient (GO:0015985)3.06677524
152ATP synthesis coupled proton transport (GO:0015986)3.06677524
153lipoprotein metabolic process (GO:0042157)3.06560554
154glycerol metabolic process (GO:0006071)3.06478632
155phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.06413329
156signal peptide processing (GO:0006465)3.03981772
157regulation of protein glycosylation (GO:0060049)3.03932749
158regulation of actin nucleation (GO:0051125)2.98322625
159vitamin transport (GO:0051180)2.98191488
160nucleotide transmembrane transport (GO:1901679)2.97950409
161actin filament depolymerization (GO:0030042)2.97772164
162antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.93102091
163ventricular cardiac muscle cell action potential (GO:0086005)2.90743343
164negative regulation of digestive system process (GO:0060457)2.90711249
165protein O-linked glycosylation (GO:0006493)2.89964111
166homocysteine metabolic process (GO:0050667)2.89476507
167leukocyte tethering or rolling (GO:0050901)2.86768891
168positive regulation of cell fate commitment (GO:0010455)2.85833964
169glucose 6-phosphate metabolic process (GO:0051156)2.85487748
170nucleotide-sugar biosynthetic process (GO:0009226)2.84007041
171negative regulation of epidermis development (GO:0045683)2.78195185
172cardiac conduction (GO:0061337)2.77459387
173vitamin A metabolic process (GO:0006776)2.75822556
174negative regulation of protein tyrosine kinase activity (GO:0061099)2.75145817
175production of molecular mediator involved in inflammatory response (GO:0002532)2.73789820
176phosphatidylglycerol metabolic process (GO:0046471)2.73544560
177amino sugar metabolic process (GO:0006040)2.72867318
178flavonoid metabolic process (GO:0009812)2.72768272
179glutamine family amino acid biosynthetic process (GO:0009084)2.72442002

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.39975692
2CDX2_20551321_ChIP-Seq_CACO-2_Human4.62583209
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.57643248
4THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse4.24001558
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.84365907
6TRIM28_21343339_ChIP-Seq_HEK293_Human3.64942905
7SOX2_27498859_Chip-Seq_STOMACH_Mouse3.30873293
8ESR1_20079471_ChIP-ChIP_T-47D_Human3.27178511
9PPARA_22158963_ChIP-Seq_LIVER_Mouse3.23886602
10CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.02327484
11PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.94361692
12GATA6_25053715_ChIP-Seq_YYC3_Human2.93596540
13* GATA4_25053715_ChIP-Seq_YYC3_Human2.91597229
14SOX2_20726797_ChIP-Seq_SW620_Human2.82842549
15ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse2.77755214
16IRF8_22096565_ChIP-ChIP_GC-B_Human2.65235275
17RXR_22158963_ChIP-Seq_LIVER_Mouse2.61356689
18HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.54743102
19CDX2_19796622_ChIP-Seq_MESCs_Mouse2.20626007
20LXR_22158963_ChIP-Seq_LIVER_Mouse2.17757015
21ESR2_21235772_ChIP-Seq_MCF-7_Human1.99770913
22FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.96365758
23* STAT1_20625510_ChIP-Seq_HELA_Human1.93622547
24ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.90688247
25ERG_21242973_ChIP-ChIP_JURKAT_Human1.88750458
26SRY_22984422_ChIP-ChIP_TESTIS_Rat1.83873804
27AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.83009305
28PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.69379860
29STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.68139598
30TCF4_18268006_ChIP-ChIP_LS174T_Human1.67349048
31BP1_19119308_ChIP-ChIP_Hs578T_Human1.66735857
32RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.66198093
33TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.65253190
34RUNX1_27514584_Chip-Seq_MCF-7_Human1.64471279
35CDX2_22108803_ChIP-Seq_LS180_Human1.55944422
36NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.55019145
37ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.54121629
38RACK7_27058665_Chip-Seq_MCF-7_Human1.53132326
39LXR_22292898_ChIP-Seq_THP-1_Human1.52707510
40SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.51380586
41FOXO3_23340844_ChIP-Seq_DLD1_Human1.49705729
42PPAR_26484153_Chip-Seq_NCI-H1993_Human1.49490907
43KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.48297629
44FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.42462879
45TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.41618494
46KLF5_25053715_ChIP-Seq_YYC3_Human1.38047103
47EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.35789010
48HNF4A_19822575_ChIP-Seq_HepG2_Human1.34017809
49SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.33598910
50MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.33091588
51TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.31538252
52ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.30976791
53KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.29854486
54CTCF_20526341_ChIP-Seq_ESCs_Human1.28610868
55CTCF_27219007_Chip-Seq_Bcells_Human1.25836282
56ATF3_27146783_Chip-Seq_COLON_Human1.22822497
57* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.22073739
58GATA2_19941826_ChIP-Seq_K562_Human1.21501661
59ZNF263_19887448_ChIP-Seq_K562_Human1.21194671
60ESR1_21235772_ChIP-Seq_MCF-7_Human1.21123494
61GATA3_24758297_ChIP-Seq_MCF-7_Human1.19277805
62* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.18807872
63P63_26484246_Chip-Seq_KERATINOCYTES_Human1.16444150
64STAT6_21828071_ChIP-Seq_BEAS2B_Human1.15391537
65PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.13665112
66ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.12580448
67SA1_27219007_Chip-Seq_ERYTHROID_Human1.11711221
68PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.10955682
69POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.10708159
70* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.10213562
71SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09747986
72UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.09161634
73FOXA1_25552417_ChIP-Seq_VCAP_Human1.09096340
74E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.08755477
75GATA1_19941826_ChIP-Seq_K562_Human1.08646250
76SA1_27219007_Chip-Seq_Bcells_Human1.08254518
77GATA1_22025678_ChIP-Seq_K562_Human1.08093783
78RAD21_21589869_ChIP-Seq_MESCs_Mouse1.07982593
79* CEBPB_22108803_ChIP-Seq_LS180_Human1.07778723
80GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06567195
81PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.06346299
82VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.06004151
83BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.03912760
84CLOCK_20551151_ChIP-Seq_293T_Human1.03448916
85DNAJC2_21179169_ChIP-ChIP_NT2_Human1.02555392
86SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.01224488
87TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00357538
88GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.99423232
89SMC4_20622854_ChIP-Seq_HELA_Human0.99405912
90RXR_22108803_ChIP-Seq_LS180_Human0.98803968
91FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.98170976
92CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.97558718
93JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.96989839
94CREB1_26743006_Chip-Seq_LNCaP_Human0.96827952
95RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96348058
96AR_21909140_ChIP-Seq_LNCAP_Human0.96135440
97CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.95202716
98CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.95198683
99NANOG_20526341_ChIP-Seq_ESCs_Human0.94935509
100BCL6_27268052_Chip-Seq_Bcells_Human0.93967713
101NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.93094214
102FOXA2_19822575_ChIP-Seq_HepG2_Human0.92918779
103DROSHA_22980978_ChIP-Seq_HELA_Human0.92698863
104BCAT_22108803_ChIP-Seq_LS180_Human0.91453735
105TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.91077188
106EGR1_19032775_ChIP-ChIP_M12_Human0.90463334
107GATA1_22383799_ChIP-Seq_G1ME_Mouse0.89528299
108FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89422122
109* PHF8_20622854_ChIP-Seq_HELA_Human0.88961223
110P68_20966046_ChIP-Seq_HELA_Human0.88954293
111STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.88329534
112TP63_22573176_ChIP-Seq_HFKS_Human0.88323166
113IRF8_21731497_ChIP-ChIP_J774_Mouse0.87912759
114KAP1_22055183_ChIP-Seq_ESCs_Mouse0.87231700
115CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.87157157
116CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85091717
117SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.84827801
118FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.84605984
119CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.84472064
120E2F1_20622854_ChIP-Seq_HELA_Human0.84253034
121TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.84127919
122* BCOR_27268052_Chip-Seq_Bcells_Human0.83832490
123ELF1_20517297_ChIP-Seq_JURKAT_Human0.83828521
124TET1_21451524_ChIP-Seq_MESCs_Mouse0.83098185
125EGR1_23403033_ChIP-Seq_LIVER_Mouse0.82318795
126NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.82109776
127GATA2_21666600_ChIP-Seq_HMVEC_Human0.81768695
128NR3C1_21868756_ChIP-Seq_MCF10A_Human0.80951518
129TCF3_18692474_ChIP-Seq_MEFs_Mouse0.77807140
130EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.76995019
131CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.75260615
132ZNF217_24962896_ChIP-Seq_MCF-7_Human0.74517541
133VDR_24787735_ChIP-Seq_THP-1_Human0.74212097
134RARG_19884340_ChIP-ChIP_MEFs_Mouse0.73870351
135TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.72018941
136GATA2_22383799_ChIP-Seq_G1ME_Mouse0.71719229

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001666_abnormal_nutrient_absorption6.84450541
2MP0003868_abnormal_feces_composition5.29196507
3MP0005360_urolithiasis5.20729933
4MP0004264_abnormal_extraembryonic_tissu4.35700859
5MP0005365_abnormal_bile_salt3.92319763
6MP0001873_stomach_inflammation3.71352955
7MP0010155_abnormal_intestine_physiology3.69916058
8MP0005085_abnormal_gallbladder_physiolo3.60463760
9MP0000490_abnormal_crypts_of3.47738901
10MP0003866_abnormal_defecation3.36176480
11MP0002139_abnormal_hepatobiliary_system3.14984702
12MP0010234_abnormal_vibrissa_follicle3.10193322
13MP0001663_abnormal_digestive_system2.92384210
14MP0001664_abnormal_digestion2.75442491
15MP0005083_abnormal_biliary_tract2.67330670
16MP0000462_abnormal_digestive_system2.59827992
17MP0005381_digestive/alimentary_phenotyp2.44369557
18MP0003252_abnormal_bile_duct2.42301722
19MP0000477_abnormal_intestine_morphology2.35835191
20MP0005165_increased_susceptibility_to2.25221965
21MP0002277_abnormal_respiratory_mucosa2.23734347
22MP0008875_abnormal_xenobiotic_pharmacok2.16178042
23MP0003705_abnormal_hypodermis_morpholog2.08239909
24MP0005409_darkened_coat_color1.94956887
25MP0005084_abnormal_gallbladder_morpholo1.93381385
26MP0005666_abnormal_adipose_tissue1.92342949
27MP0002876_abnormal_thyroid_physiology1.79605612
28MP0008004_abnormal_stomach_pH1.73256399
29MP0003183_abnormal_peptide_metabolism1.72103034
30MP0005670_abnormal_white_adipose1.67311191
31MP0000465_gastrointestinal_hemorrhage1.66139984
32MP0003806_abnormal_nucleotide_metabolis1.65069796
33MP0000537_abnormal_urethra_morphology1.64265635
34MP0005220_abnormal_exocrine_pancreas1.63719705
35MP0005448_abnormal_energy_balance1.58245573
36MP0003300_gastrointestinal_ulcer1.48969813
37MP0010352_gastrointestinal_tract_polyps1.46700977
38MP0001764_abnormal_homeostasis1.44813528
39MP0005451_abnormal_body_composition1.43173010
40MP0009780_abnormal_chondrocyte_physiolo1.41217862
41MP0004019_abnormal_vitamin_homeostasis1.39554892
42MP0003191_abnormal_cellular_cholesterol1.32515100
43MP0004782_abnormal_surfactant_physiolog1.30752579
44MP0001188_hyperpigmentation1.26847223
45MP0010329_abnormal_lipoprotein_level1.26531696
46MP0006054_spinal_hemorrhage1.22017376
47MP0002138_abnormal_hepatobiliary_system1.21943331
48MP0005375_adipose_tissue_phenotype1.20309049
49MP0002118_abnormal_lipid_homeostasis1.16722622
50MP0000470_abnormal_stomach_morphology1.13014228
51MP0000230_abnormal_systemic_arterial1.12658684
52MP0004858_abnormal_nervous_system1.09842696
53MP0002822_catalepsy1.09417211
54MP0009643_abnormal_urine_homeostasis1.09130972
55MP0003878_abnormal_ear_physiology1.06579984
56MP0005377_hearing/vestibular/ear_phenot1.06579984
57MP0001756_abnormal_urination1.03628923
58MP0005332_abnormal_amino_acid1.03539712
59MP0002693_abnormal_pancreas_physiology1.01894954
60MP0009840_abnormal_foam_cell0.98181385
61MP0001845_abnormal_inflammatory_respons0.97228917
62MP0001849_ear_inflammation0.96794558
63MP0003879_abnormal_hair_cell0.93157955
64MP0004185_abnormal_adipocyte_glucose0.87533660
65MP0002796_impaired_skin_barrier0.84139821
66MP0002166_altered_tumor_susceptibility0.83801563
67MP0009785_altered_susceptibility_to0.82239069
68MP0002971_abnormal_brown_adipose0.80606000
69MP0002009_preneoplasia0.78052103
70MP0001944_abnormal_pancreas_morphology0.77112522
71MP0003724_increased_susceptibility_to0.76197214
72MP0003718_maternal_effect0.75676930
73MP0008872_abnormal_physiological_respon0.75412465
74MP0000538_abnormal_urinary_bladder0.74576508
75MP0005334_abnormal_fat_pad0.72522923
76MP0001765_abnormal_ion_homeostasis0.71547300
77MP0005535_abnormal_body_temperature0.71317469
78MP0005166_decreased_susceptibility_to0.70820266
79MP0000609_abnormal_liver_physiology0.69928300
80MP0002006_tumorigenesis0.68264485
81MP0009115_abnormal_fat_cell0.66319729
82MP0008469_abnormal_protein_level0.64514516
83MP0005025_abnormal_response_to0.63832120
84MP0006082_CNS_inflammation0.63791389
85MP0003959_abnormal_lean_body0.63318370
86MP0003303_peritoneal_inflammation0.61704553
87MP0000604_amyloidosis0.61490438
88MP0005310_abnormal_salivary_gland0.59294203
89MP0003638_abnormal_response/metabolism_0.58864717
90MP0003329_amyloid_beta_deposits0.58337951
91MP0002896_abnormal_bone_mineralization0.58149033
92MP0010678_abnormal_skin_adnexa0.57560041
93MP0005319_abnormal_enzyme/_coenzyme0.57327274
94MP0002089_abnormal_postnatal_growth/wei0.57247798
95MP0003123_paternal_imprinting0.57030839
96MP0001485_abnormal_pinna_reflex0.56388524
97MP0005387_immune_system_phenotype0.55871524
98MP0001790_abnormal_immune_system0.55871524
99MP0003283_abnormal_digestive_organ0.54485821
100MP0010386_abnormal_urinary_bladder0.52924428
101MP0000249_abnormal_blood_vessel0.51939288
102MP0000566_synostosis0.51555201
103MP0003953_abnormal_hormone_level0.50314227
104MP0005058_abnormal_lysosome_morphology0.50101851
105MP0004947_skin_inflammation0.49555946
106MP0005636_abnormal_mineral_homeostasis0.48328056
107MP0002098_abnormal_vibrissa_morphology0.48166449
108MP0004043_abnormal_pH_regulation0.47961414
109MP0003436_decreased_susceptibility_to0.46957310
110MP0002078_abnormal_glucose_homeostasis0.46307167
111MP0000003_abnormal_adipose_tissue0.45711039
112MP0009642_abnormal_blood_homeostasis0.44759802
113MP0000467_abnormal_esophagus_morphology0.44236154
114MP0001501_abnormal_sleep_pattern0.43080437
115MP0002148_abnormal_hypersensitivity_rea0.42562908
116MP0009765_abnormal_xenobiotic_induced0.41567259
117MP0005167_abnormal_blood-brain_barrier0.41344359
118MP0003453_abnormal_keratinocyte_physiol0.40706807
119MP0003828_pulmonary_edema0.40534817
120MP0004484_altered_response_of0.39608828
121MP0005076_abnormal_cell_differentiation0.38123833
122MP0000598_abnormal_liver_morphology0.37706458
123MP0000678_abnormal_parathyroid_gland0.37314515
124MP0004147_increased_porphyrin_level0.36156531
125MP0005584_abnormal_enzyme/coenzyme_acti0.35934814
126MP0002136_abnormal_kidney_physiology0.35812739
127MP0004270_analgesia0.35376439
128MP0005501_abnormal_skin_physiology0.35022643
129MP0009379_abnormal_foot_pigmentation0.34630165
130MP0001216_abnormal_epidermal_layer0.34275981

Predicted human phenotypes

RankGene SetZ-score
1Micronodular cirrhosis (HP:0001413)5.54476278
2Abnormality of renin-angiotensin system (HP:0000847)5.45546690
3Abdominal distention (HP:0003270)5.00923867
4Ileus (HP:0002595)4.97108488
5Right ventricular cardiomyopathy (HP:0011663)4.75700770
6Alkalosis (HP:0001948)4.63895563
7Late onset (HP:0003584)4.43120213
8Fat malabsorption (HP:0002630)4.35485129
9Ketoacidosis (HP:0001993)4.04301893
10Ventricular fibrillation (HP:0001663)4.04129537
11Esophageal varix (HP:0002040)4.03363891
12Abnormality of the vitamin B12 metabolism (HP:0004341)3.97430301
13Congenital sensorineural hearing impairment (HP:0008527)3.96308411
14Syncope (HP:0001279)3.85888692
15Abnormality of glutamine family amino acid metabolism (HP:0010902)3.77563011
16Abnormality of vitamin B metabolism (HP:0004340)3.74684256
17Hyperaldosteronism (HP:0000859)3.72151948
18Abnormality of chloride homeostasis (HP:0011422)3.67077777
19Steatorrhea (HP:0002570)3.53954733
20Prolonged QT interval (HP:0001657)3.49884650
21Widely patent fontanelles and sutures (HP:0004492)3.44057544
22Acanthocytosis (HP:0001927)3.41883623
23Bundle branch block (HP:0011710)3.28077151
24Exocrine pancreatic insufficiency (HP:0001738)3.23301684
25Abnormality of vitamin metabolism (HP:0100508)3.20091109
26Systemic lupus erythematosus (HP:0002725)3.17966660
27Hyperparathyroidism (HP:0000843)3.16825740
28Malnutrition (HP:0004395)3.12648442
29Hypokalemia (HP:0002900)2.99252531
30Pigmentary retinal degeneration (HP:0001146)2.97624159
31Abnormality of sulfur amino acid metabolism (HP:0004339)2.93846422
32Nausea (HP:0002018)2.93439826
33Chronic diarrhea (HP:0002028)2.85295822
34Hypercortisolism (HP:0001578)2.83696733
35Ketosis (HP:0001946)2.82612002
36Hypoglycemic coma (HP:0001325)2.82561940
37Conjugated hyperbilirubinemia (HP:0002908)2.81463801
38Abnormality of the pancreatic islet cells (HP:0006476)2.79848192
39Abnormality of endocrine pancreas physiology (HP:0012093)2.79848192
40Palpitations (HP:0001962)2.79128445
41Hyponatremia (HP:0002902)2.78990837
42Glycosuria (HP:0003076)2.76899304
43Abnormality of urine glucose concentration (HP:0011016)2.76899304
44Gout (HP:0001997)2.75775795
45Hemorrhage of the eye (HP:0011885)2.75388698
46Abnormality of potassium homeostasis (HP:0011042)2.70766367
47Intrahepatic cholestasis (HP:0001406)2.69446373
48Abnormal foot bone ossification (HP:0010675)2.67212866
49Posterior subcapsular cataract (HP:0007787)2.66983112
50Woolly hair (HP:0002224)2.64471969
51Abnormality of monocarboxylic acid metabolism (HP:0010996)2.58808181
52Conjunctival hamartoma (HP:0100780)2.58707002
53Insulin resistance (HP:0000855)2.56252127
54Nephrolithiasis (HP:0000787)2.55221493
55Increased muscle lipid content (HP:0009058)2.53793498
56Generalized aminoaciduria (HP:0002909)2.53404120
57Abnormality of serine family amino acid metabolism (HP:0010894)2.50383479
58Abnormality of glycine metabolism (HP:0010895)2.50383479
59Wide cranial sutures (HP:0010537)2.49388268
60Flattened epiphyses (HP:0003071)2.48521878
61Eczematoid dermatitis (HP:0000976)2.48364281
62Abnormality of aspartate family amino acid metabolism (HP:0010899)2.47593302
63Abnormality of the distal phalanx of the thumb (HP:0009617)2.40287497
64Neonatal short-limb short stature (HP:0008921)2.39501700
65Hyperammonemia (HP:0001987)2.39009018
66Flat capital femoral epiphysis (HP:0003370)2.36863671
67Renal tubular acidosis (HP:0001947)2.34667263
68Protuberant abdomen (HP:0001538)2.34625769
69Pancreatitis (HP:0001733)2.34126154
70Increased intramyocellular lipid droplets (HP:0012240)2.33395237
71Dicarboxylic aciduria (HP:0003215)2.31952789
72Abnormality of dicarboxylic acid metabolism (HP:0010995)2.31952789
73Hypotension (HP:0002615)2.31601724
74Thin bony cortex (HP:0002753)2.31340947
75Bone cyst (HP:0012062)2.30067928
76Focal segmental glomerulosclerosis (HP:0000097)2.27756913
77Hypolipoproteinemia (HP:0010981)2.26612011
78Acute encephalopathy (HP:0006846)2.26224776
79Abnormality of purine metabolism (HP:0004352)2.23227333
80Lethargy (HP:0001254)2.22292511
81Hypobetalipoproteinemia (HP:0003563)2.20845847
82Dehydration (HP:0001944)2.20226667
83Symptomatic seizures (HP:0011145)2.18618994
84Reduced antithrombin III activity (HP:0001976)2.17848123
85Enlarged epiphyses (HP:0010580)2.17742701
86Villous atrophy (HP:0011473)2.17428188
87Abnormality of small intestinal villus morphology (HP:0011472)2.17428188
88Abnormality of proline metabolism (HP:0010907)2.16418208
89Hydroxyprolinuria (HP:0003080)2.16418208
90Confusion (HP:0001289)2.16139900
91Hypophosphatemia (HP:0002148)2.15407313
92Metabolic acidosis (HP:0001942)2.15226109
93Abnormal EKG (HP:0003115)2.14943932
94Hyperactive renin-angiotensin system (HP:0000841)2.14005921
95Hepatic necrosis (HP:0002605)2.13779878
96Pili torti (HP:0003777)2.13318710
97Hyperglycinuria (HP:0003108)2.10798281
98Xanthomatosis (HP:0000991)2.10592829
99Cerebral palsy (HP:0100021)2.09376768
100Visceral angiomatosis (HP:0100761)2.09309753
101Abnormality of the intrinsic pathway (HP:0010989)2.07781895
102Delayed epiphyseal ossification (HP:0002663)2.07453708
103Abnormality of magnesium homeostasis (HP:0004921)2.07402516
104Adrenal overactivity (HP:0002717)2.06673654
105Abnormality of sodium homeostasis (HP:0010931)2.06049717
106Neoplasm of the rectum (HP:0100743)2.05397394
107Abnormal protein glycosylation (HP:0012346)2.04331591
108Abnormal glycosylation (HP:0012345)2.04331591
109Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.04331591
110Abnormal protein N-linked glycosylation (HP:0012347)2.04331591
111Abnormal pancreas size (HP:0012094)2.02248065
112Abnormality of fatty-acid metabolism (HP:0004359)2.01246672
113Multiple lipomas (HP:0001012)2.01162925
114Hyperkalemia (HP:0002153)2.01015221
115Proximal tubulopathy (HP:0000114)2.00258248
116Abnormality of the gastric mucosa (HP:0004295)2.00013150
117Gastrointestinal dysmotility (HP:0002579)1.97902576
118Facial shape deformation (HP:0011334)1.97399683
119Potter facies (HP:0002009)1.97399683
120Abnormal mitochondria in muscle tissue (HP:0008316)1.97351128
121Abnormal tarsal ossification (HP:0008369)1.96965723
122Ventricular arrhythmia (HP:0004308)1.96054492
123Abnormality of aromatic amino acid family metabolism (HP:0004338)1.95768762
124Hyperphosphaturia (HP:0003109)1.95250846
125Megaloblastic anemia (HP:0001889)1.95159600
126Abnormal urine phosphate concentration (HP:0012599)1.94939033
127Petechiae (HP:0000967)1.93745397
128Abnormality of nucleobase metabolism (HP:0010932)1.93511903
129Rectal prolapse (HP:0002035)1.92906061
130Abnormal biliary tract morphology (HP:0012440)1.92255401
131Increased purine levels (HP:0004368)1.91996923
132Hyperuricemia (HP:0002149)1.91996923
133Abnormality of pyrimidine metabolism (HP:0004353)1.91551744
134Abnormality of the costochondral junction (HP:0000919)1.88395389
135Hyperphosphatemia (HP:0002905)1.87701900
136Mitochondrial inheritance (HP:0001427)1.87352707
137Neoplasm of the small intestine (HP:0100833)1.86699668
138Chorioretinal atrophy (HP:0000533)1.86607317
139Decreased circulating renin level (HP:0003351)1.83883127
140Biliary tract neoplasm (HP:0100574)1.82859032
141Pheochromocytoma (HP:0002666)1.82021241
142Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.81805782
143Flat acetabular roof (HP:0003180)1.81670773
144Premature skin wrinkling (HP:0100678)1.81509107
145Hemangiomatosis (HP:0007461)1.81341618
146Myopathic facies (HP:0002058)1.80814523
147Acute necrotizing encephalopathy (HP:0006965)1.79939821
148Renal tubular dysfunction (HP:0000124)1.79847101
149Metabolic alkalosis (HP:0200114)1.79554192
150Abnormal hair laboratory examination (HP:0003328)1.76231874
151Glomerulosclerosis (HP:0000096)1.75603700

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B8.11731745
2FRK6.34938010
3NME15.79096262
4MAP2K24.49074385
5EPHA24.21566253
6RPS6KB23.68921401
7ERN13.30655770
8MST42.67381709
9PTK62.48374673
10MST1R2.42365921
11LMTK22.37550675
12BCKDK2.22508476
13OXSR11.99568075
14TRIB31.96462015
15PIK3CA1.93087145
16MAP2K11.90985290
17MAP2K61.84694628
18TEC1.73638697
19BLK1.73083607
20MAP3K21.71214428
21TESK11.70697979
22TAOK11.70682842
23TESK21.67807333
24PKN21.65491865
25EEF2K1.63297398
26STK241.56949995
27PRKG21.54159590
28MYLK1.50365445
29MAP3K111.50186383
30CAMK2D1.46673107
31EPHA31.46480498
32TAOK31.40626029
33CAMK2B1.40101497
34FGFR41.36580600
35GRK61.30970889
36MAP3K121.22186409
37TNIK1.21348356
38KSR21.19320127
39EPHB21.18009500
40MAPKAPK31.16629229
41TYK21.16067829
42NME21.13647591
43CAMK2G1.13003880
44MAP3K101.08774558
45EPHB11.05393389
46PIM20.99502637
47CASK0.92721208
48MAP3K30.92529068
49PTK20.91363991
50PAK40.91036131
51NLK0.86739207
52LATS10.86656359
53FGFR30.82548340
54MAP3K70.80602565
55ILK0.80572308
56SCYL20.80456456
57MAP3K80.78639269
58EPHA40.76540088
59NUAK10.74690123
60MAP3K10.74333935
61LRRK20.71638452
62PRKCI0.69233169
63MET0.68395209
64FER0.67456559
65ABL20.66968929
66PRKACG0.66093762
67RIPK10.64786329
68DYRK1B0.58994184
69MAPK110.58814477
70CSK0.58058308
71PRPF4B0.57849630
72CDC42BPA0.56732402
73ERBB20.55143219
74LIMK10.50449432
75IRAK10.48053954
76PAK20.46900711
77PDK30.45965310
78PDK40.45965310
79TBK10.45465871
80MAP3K60.45060965
81PDPK10.43614834
82WNK40.42116505
83PRKCQ0.41870536
84CAMKK10.41323402
85RIPK40.40307516
86STK100.40148712
87CDK190.38749170
88MAPKAPK20.38376302
89PAK10.38366492
90PIM10.38326494
91CSNK1A10.38180828
92PDK20.37749485
93BMPR20.36898703
94INSRR0.36739586
95AKT30.36179180
96CAMK10.36020489
97PRKCA0.35964921
98DAPK30.34783219
99RET0.33538205
100ZAP700.33279918
101MAPK150.32496238
102JAK20.31896544
103ADRBK20.31320476
104ITK0.31273100
105MATK0.31211271
106JAK10.30965535
107PDK10.30845854
108SRC0.30394168
109FYN0.30334752
110MAP4K10.29914266
111PAK30.29607581
112STK390.27760934
113PRKAA20.27355274
114YES10.27079130
115EIF2AK30.26438995
116TAOK20.26010207
117IKBKE0.25898822
118CAMK2A0.24404478
119DAPK20.23201971
120PRKCZ0.23051456
121LYN0.22664347
122NEK60.22147185
123PRKCE0.21929046
124MAP2K30.21815043
125PRKCD0.20443849
126BCR0.20267426
127IGF1R0.19894511
128KDR0.19329376
129DDR20.18843364
130GRK10.18628557
131CSNK1G30.17812141
132BMX0.17739692
133PIK3CG0.17632595
134PRKCB0.17071860
135MAP3K140.16612312
136DMPK0.16351631
137RPS6KA20.14501457
138PRKACA0.14376765
139MAPK70.11380454

Predicted pathways (KEGG)

RankGene SetZ-score
1Fat digestion and absorption_Homo sapiens_hsa049755.73927941
2Pancreatic secretion_Homo sapiens_hsa049723.64243865
3Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005333.44211172
4Sulfur metabolism_Homo sapiens_hsa009203.29877164
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.13649667
6Maturity onset diabetes of the young_Homo sapiens_hsa049503.05278630
7Linoleic acid metabolism_Homo sapiens_hsa005913.00628666
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.71185794
9Protein digestion and absorption_Homo sapiens_hsa049742.49427243
10Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.47093490
11Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005122.25738865
12Retinol metabolism_Homo sapiens_hsa008301.99308920
13Histidine metabolism_Homo sapiens_hsa003401.93049848
14Cyanoamino acid metabolism_Homo sapiens_hsa004601.92571394
15Glycerolipid metabolism_Homo sapiens_hsa005611.86593315
16Renin-angiotensin system_Homo sapiens_hsa046141.76650800
17Steroid hormone biosynthesis_Homo sapiens_hsa001401.74361036
18Arachidonic acid metabolism_Homo sapiens_hsa005901.71423677
19Mineral absorption_Homo sapiens_hsa049781.64382229
20Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.62153096
21Pentose and glucuronate interconversions_Homo sapiens_hsa000401.60534564
22Tryptophan metabolism_Homo sapiens_hsa003801.59763884
23Fructose and mannose metabolism_Homo sapiens_hsa000511.57233630
24Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.53522724
25Galactose metabolism_Homo sapiens_hsa000521.52291459
26Ether lipid metabolism_Homo sapiens_hsa005651.52010678
27Bile secretion_Homo sapiens_hsa049761.51408708
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.47703439
29Arginine and proline metabolism_Homo sapiens_hsa003301.45266049
30Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.45101800
31Fatty acid degradation_Homo sapiens_hsa000711.44942480
32Pyruvate metabolism_Homo sapiens_hsa006201.43323567
33Vitamin digestion and absorption_Homo sapiens_hsa049771.40530144
34Folate biosynthesis_Homo sapiens_hsa007901.33674716
35PPAR signaling pathway_Homo sapiens_hsa033201.31922339
36Glutathione metabolism_Homo sapiens_hsa004801.19808840
372-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.19114993
38Oxidative phosphorylation_Homo sapiens_hsa001901.19094038
39Starch and sucrose metabolism_Homo sapiens_hsa005001.16574236
40Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.16059980
41Vibrio cholerae infection_Homo sapiens_hsa051101.14827961
42Parkinsons disease_Homo sapiens_hsa050121.14537435
43Intestinal immune network for IgA production_Homo sapiens_hsa046721.06998985
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.03228979
45Nitrogen metabolism_Homo sapiens_hsa009101.00889890
46Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.99660607
47Carbohydrate digestion and absorption_Homo sapiens_hsa049730.97831507
48Protein export_Homo sapiens_hsa030600.97051274
49beta-Alanine metabolism_Homo sapiens_hsa004100.95598054
50Alzheimers disease_Homo sapiens_hsa050100.93457664
51Arginine biosynthesis_Homo sapiens_hsa002200.89723510
52Asthma_Homo sapiens_hsa053100.88332865
53Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87735106
54Propanoate metabolism_Homo sapiens_hsa006400.84559565
55Pentose phosphate pathway_Homo sapiens_hsa000300.82020815
56Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.81976894
57Carbon metabolism_Homo sapiens_hsa012000.78116662
58Selenocompound metabolism_Homo sapiens_hsa004500.77744073
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.76956138
60Glycerophospholipid metabolism_Homo sapiens_hsa005640.72572023
61Tight junction_Homo sapiens_hsa045300.72514063
62Phenylalanine metabolism_Homo sapiens_hsa003600.72280093
63Hepatitis C_Homo sapiens_hsa051600.70617052
64Sulfur relay system_Homo sapiens_hsa041220.70116451
65Leukocyte transendothelial migration_Homo sapiens_hsa046700.69142674
66Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.68268604
67Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.68141931
68Allograft rejection_Homo sapiens_hsa053300.63519401
69Biosynthesis of amino acids_Homo sapiens_hsa012300.59287557
70Autoimmune thyroid disease_Homo sapiens_hsa053200.59000999
71Caffeine metabolism_Homo sapiens_hsa002320.58061810
72Graft-versus-host disease_Homo sapiens_hsa053320.56907082
73Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.55884925
74Tyrosine metabolism_Homo sapiens_hsa003500.54079640
75Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.53274645
76N-Glycan biosynthesis_Homo sapiens_hsa005100.50861176
77Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.48875419
78Huntingtons disease_Homo sapiens_hsa050160.48370947
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.46525535
80Staphylococcus aureus infection_Homo sapiens_hsa051500.45674461
81Insulin secretion_Homo sapiens_hsa049110.43964767
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43881859
83Type I diabetes mellitus_Homo sapiens_hsa049400.43312043
84Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.42342873
85Butanoate metabolism_Homo sapiens_hsa006500.41576704
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.39962905
87Cardiac muscle contraction_Homo sapiens_hsa042600.38825548
88Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.38596527
89Metabolic pathways_Homo sapiens_hsa011000.38328109
90Chemical carcinogenesis_Homo sapiens_hsa052040.35790509
91Thyroid hormone synthesis_Homo sapiens_hsa049180.33389321
92Thyroid cancer_Homo sapiens_hsa052160.32615804
93Gastric acid secretion_Homo sapiens_hsa049710.27687433
94Cysteine and methionine metabolism_Homo sapiens_hsa002700.26885509
95Insulin resistance_Homo sapiens_hsa049310.25383610
96Bladder cancer_Homo sapiens_hsa052190.24883480
97Influenza A_Homo sapiens_hsa051640.24775792
98Peroxisome_Homo sapiens_hsa041460.21941779
99ABC transporters_Homo sapiens_hsa020100.21616312
100Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21228287
101Fatty acid biosynthesis_Homo sapiens_hsa000610.20396914
102Salmonella infection_Homo sapiens_hsa051320.19614645
103Adipocytokine signaling pathway_Homo sapiens_hsa049200.19433713
104Primary bile acid biosynthesis_Homo sapiens_hsa001200.18729341
105Antigen processing and presentation_Homo sapiens_hsa046120.18119202
106VEGF signaling pathway_Homo sapiens_hsa043700.16586166
107Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.16272958
108Fatty acid metabolism_Homo sapiens_hsa012120.16078406
109Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.15581893
110Steroid biosynthesis_Homo sapiens_hsa001000.13375909
111Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.11953760
112Renin secretion_Homo sapiens_hsa049240.11349453
113Pertussis_Homo sapiens_hsa051330.10401858
114Fatty acid elongation_Homo sapiens_hsa000620.10032226
115Leishmaniasis_Homo sapiens_hsa051400.07841111
116Sphingolipid metabolism_Homo sapiens_hsa006000.07757554
117Drug metabolism - other enzymes_Homo sapiens_hsa009830.07567912
118Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.07136412
119Other glycan degradation_Homo sapiens_hsa005110.04827446
120Amoebiasis_Homo sapiens_hsa051460.04477552
121Cocaine addiction_Homo sapiens_hsa050300.04161753
122Salivary secretion_Homo sapiens_hsa049700.03165714
123African trypanosomiasis_Homo sapiens_hsa051430.02932911
124Glucagon signaling pathway_Homo sapiens_hsa049220.01256580
125Viral myocarditis_Homo sapiens_hsa05416-0.0320468
126Toxoplasmosis_Homo sapiens_hsa05145-0.0317578
127Complement and coagulation cascades_Homo sapiens_hsa04610-0.0117142
128Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142-0.0110108
129Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0069282
130Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040-0.0044721

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