

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.40729330 |
| 2 | proteasome assembly (GO:0043248) | 5.65640183 |
| 3 | protein complex biogenesis (GO:0070271) | 5.48905110 |
| 4 | mitochondrial respiratory chain complex assembly (GO:0033108) | 5.08301796 |
| 5 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.84041040 |
| 6 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.84041040 |
| 7 | termination of RNA polymerase III transcription (GO:0006386) | 4.78900227 |
| 8 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 4.78900227 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 4.58764499 |
| 10 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.50015622 |
| 11 | rRNA modification (GO:0000154) | 4.38842441 |
| 12 | platelet dense granule organization (GO:0060155) | 4.30829127 |
| 13 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.22528976 |
| 14 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.22049211 |
| 15 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.19437112 |
| 16 | 7-methylguanosine mRNA capping (GO:0006370) | 4.18814589 |
| 17 | RNA capping (GO:0036260) | 4.11562609 |
| 18 | 7-methylguanosine RNA capping (GO:0009452) | 4.11562609 |
| 19 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.11186315 |
| 20 | negative regulation of ligase activity (GO:0051352) | 4.11186315 |
| 21 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.09917261 |
| 22 | cytochrome complex assembly (GO:0017004) | 4.09205361 |
| 23 | formation of translation preinitiation complex (GO:0001731) | 4.08730517 |
| 24 | respiratory chain complex IV assembly (GO:0008535) | 4.06942129 |
| 25 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.01738950 |
| 26 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.98657565 |
| 27 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.98361289 |
| 28 | maturation of SSU-rRNA (GO:0030490) | 3.98143049 |
| 29 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.96133390 |
| 30 | mannosylation (GO:0097502) | 3.95365539 |
| 31 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.93810142 |
| 32 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.93810142 |
| 33 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.93810142 |
| 34 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.93359975 |
| 35 | pseudouridine synthesis (GO:0001522) | 3.90311041 |
| 36 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.90029502 |
| 37 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.90029502 |
| 38 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.89844036 |
| 39 | ATP synthesis coupled proton transport (GO:0015986) | 3.85129153 |
| 40 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.85129153 |
| 41 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.85073111 |
| 42 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.85073111 |
| 43 | ribosome biogenesis (GO:0042254) | 3.81547620 |
| 44 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.80016505 |
| 45 | purine nucleobase biosynthetic process (GO:0009113) | 3.78455473 |
| 46 | ribosomal small subunit biogenesis (GO:0042274) | 3.77821868 |
| 47 | base-excision repair, AP site formation (GO:0006285) | 3.77110824 |
| 48 | nucleobase biosynthetic process (GO:0046112) | 3.76026230 |
| 49 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.75843338 |
| 50 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.75695650 |
| 51 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.74466684 |
| 52 | transcription from RNA polymerase I promoter (GO:0006360) | 3.74098440 |
| 53 | telomere maintenance via recombination (GO:0000722) | 3.74026775 |
| 54 | electron transport chain (GO:0022900) | 3.73957024 |
| 55 | peptidyl-histidine modification (GO:0018202) | 3.73952064 |
| 56 | respiratory electron transport chain (GO:0022904) | 3.73912890 |
| 57 | ribosomal large subunit biogenesis (GO:0042273) | 3.72690773 |
| 58 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.69401779 |
| 59 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.66074273 |
| 60 | ubiquinone biosynthetic process (GO:0006744) | 3.57502618 |
| 61 | positive regulation of ligase activity (GO:0051351) | 3.56628787 |
| 62 | DNA strand elongation (GO:0022616) | 3.55886683 |
| 63 | termination of RNA polymerase I transcription (GO:0006363) | 3.55351584 |
| 64 | rRNA processing (GO:0006364) | 3.53618484 |
| 65 | ribosome assembly (GO:0042255) | 3.52911608 |
| 66 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.52455603 |
| 67 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.50545313 |
| 68 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.49198470 |
| 69 | spliceosomal snRNP assembly (GO:0000387) | 3.48962309 |
| 70 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.48812850 |
| 71 | amino acid salvage (GO:0043102) | 3.46984594 |
| 72 | L-methionine salvage (GO:0071267) | 3.46984594 |
| 73 | L-methionine biosynthetic process (GO:0071265) | 3.46984594 |
| 74 | protein-cofactor linkage (GO:0018065) | 3.46579386 |
| 75 | viral transcription (GO:0019083) | 3.44234754 |
| 76 | translation (GO:0006412) | 3.40948295 |
| 77 | rRNA metabolic process (GO:0016072) | 3.39746582 |
| 78 | GDP-mannose metabolic process (GO:0019673) | 3.39392113 |
| 79 | translational termination (GO:0006415) | 3.39308496 |
| 80 | GTP biosynthetic process (GO:0006183) | 3.38843867 |
| 81 | protein targeting to mitochondrion (GO:0006626) | 3.38467638 |
| 82 | cellular component biogenesis (GO:0044085) | 3.38282427 |
| 83 | regulation of mitochondrial translation (GO:0070129) | 3.36377447 |
| 84 | chaperone-mediated protein transport (GO:0072321) | 3.34678311 |
| 85 | tRNA processing (GO:0008033) | 3.34505164 |
| 86 | establishment of protein localization to mitochondrion (GO:0072655) | 3.31088025 |
| 87 | mitotic metaphase plate congression (GO:0007080) | 3.29538853 |
| 88 | rRNA methylation (GO:0031167) | 3.28009272 |
| 89 | DNA replication checkpoint (GO:0000076) | 3.27342717 |
| 90 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.27075451 |
| 91 | protein deneddylation (GO:0000338) | 3.26790467 |
| 92 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.25012480 |
| 93 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.24729416 |
| 94 | metallo-sulfur cluster assembly (GO:0031163) | 3.24563744 |
| 95 | iron-sulfur cluster assembly (GO:0016226) | 3.24563744 |
| 96 | mitotic recombination (GO:0006312) | 3.24473238 |
| 97 | viral mRNA export from host cell nucleus (GO:0046784) | 3.21605500 |
| 98 | purine nucleotide salvage (GO:0032261) | 3.20126236 |
| 99 | translational initiation (GO:0006413) | 3.19953091 |
| 100 | GMP metabolic process (GO:0046037) | 3.19628378 |
| 101 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.19604649 |
| 102 | maturation of 5.8S rRNA (GO:0000460) | 3.19310723 |
| 103 | protein localization to mitochondrion (GO:0070585) | 3.18317642 |
| 104 | regulation of ligase activity (GO:0051340) | 3.18226983 |
| 105 | ubiquinone metabolic process (GO:0006743) | 3.15998792 |
| 106 | cotranslational protein targeting to membrane (GO:0006613) | 3.14766430 |
| 107 | telomere maintenance via telomere lengthening (GO:0010833) | 3.14372002 |
| 108 | DNA replication initiation (GO:0006270) | 3.14095133 |
| 109 | cullin deneddylation (GO:0010388) | 3.13379734 |
| 110 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.12985424 |
| 111 | translational elongation (GO:0006414) | 3.12911479 |
| 112 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.12724182 |
| 113 | adenosine metabolic process (GO:0046085) | 3.12541174 |
| 114 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.12334059 |
| 115 | positive regulation of cell cycle arrest (GO:0071158) | 3.11361499 |
| 116 | protein targeting to ER (GO:0045047) | 3.10463431 |
| 117 | GPI anchor metabolic process (GO:0006505) | 3.10008190 |
| 118 | deoxyribonucleotide catabolic process (GO:0009264) | 3.09964863 |
| 119 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.08825877 |
| 120 | tRNA modification (GO:0006400) | 3.07651066 |
| 121 | cell cycle G1/S phase transition (GO:0044843) | 3.07395710 |
| 122 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.07395710 |
| 123 | protein neddylation (GO:0045116) | 3.06970599 |
| 124 | CENP-A containing nucleosome assembly (GO:0034080) | 3.06189624 |
| 125 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.05024088 |
| 126 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.04523084 |
| 127 | NADH dehydrogenase complex assembly (GO:0010257) | 3.04523084 |
| 128 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.04523084 |
| 129 | C-terminal protein lipidation (GO:0006501) | 3.04445190 |
| 130 | GPI anchor biosynthetic process (GO:0006506) | 3.04096208 |
| 131 | protein localization to endoplasmic reticulum (GO:0070972) | 3.03864369 |
| 132 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 3.03114924 |
| 133 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.02025262 |
| 134 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 2.93601261 |
| 135 | ATP hydrolysis coupled proton transport (GO:0015991) | 2.93601261 |
| 136 | deoxyribose phosphate catabolic process (GO:0046386) | 2.90258867 |
| 137 | intracellular protein transmembrane import (GO:0044743) | 2.90254740 |
| 138 | hydrogen ion transmembrane transport (GO:1902600) | 2.87600972 |
| 139 | mitochondrial RNA metabolic process (GO:0000959) | 2.86439996 |
| 140 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.84003418 |
| 141 | inner mitochondrial membrane organization (GO:0007007) | 2.83896982 |
| 142 | C-terminal protein amino acid modification (GO:0018410) | 2.83101332 |
| 143 | positive regulation of prostaglandin secretion (GO:0032308) | 2.78933326 |
| 144 | proton transport (GO:0015992) | 2.78585172 |
| 145 | behavioral response to nicotine (GO:0035095) | 2.76899063 |
| 146 | L-fucose catabolic process (GO:0042355) | 2.74556123 |
| 147 | fucose catabolic process (GO:0019317) | 2.74556123 |
| 148 | L-fucose metabolic process (GO:0042354) | 2.74556123 |
| 149 | hydrogen transport (GO:0006818) | 2.74295253 |
| 150 | UTP biosynthetic process (GO:0006228) | 2.74292373 |
| 151 | negative regulation of telomere maintenance (GO:0032205) | 2.73435039 |
| 152 | quinone biosynthetic process (GO:1901663) | 2.70273222 |
| 153 | tryptophan catabolic process (GO:0006569) | 2.68508189 |
| 154 | indole-containing compound catabolic process (GO:0042436) | 2.68508189 |
| 155 | indolalkylamine catabolic process (GO:0046218) | 2.68508189 |
| 156 | kynurenine metabolic process (GO:0070189) | 2.68361287 |
| 157 | response to pheromone (GO:0019236) | 2.68152026 |
| 158 | purine-containing compound salvage (GO:0043101) | 2.67782278 |
| 159 | autophagic vacuole fusion (GO:0000046) | 2.64644664 |
| 160 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.63223948 |
| 161 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.60701490 |
| 162 | adaptation of signaling pathway (GO:0023058) | 2.59778658 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.25496231 |
| 2 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.13195416 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.99310327 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.95885319 |
| 5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.82620677 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.79618506 |
| 7 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.61641125 |
| 8 | * NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.59536741 |
| 9 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.59268444 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.45572371 |
| 11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.27070698 |
| 12 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 3.04448007 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.03668333 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.00336427 |
| 15 | * HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.74145742 |
| 16 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.73886760 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.73373335 |
| 18 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.69988643 |
| 19 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.69909850 |
| 20 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.62636611 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.62474655 |
| 22 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.53377704 |
| 23 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.39724937 |
| 24 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.29338795 |
| 25 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.26549586 |
| 26 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.26165603 |
| 27 | * SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.24119604 |
| 28 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.23361818 |
| 29 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.18388933 |
| 30 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.15468587 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.10307664 |
| 32 | * GABP_19822575_ChIP-Seq_HepG2_Human | 2.07332849 |
| 33 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.06998353 |
| 34 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.04086447 |
| 35 | * PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.01829762 |
| 36 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.96889620 |
| 37 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.90795380 |
| 38 | VDR_22108803_ChIP-Seq_LS180_Human | 1.89862540 |
| 39 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.87606887 |
| 40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.86905668 |
| 41 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.85865716 |
| 42 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.80082083 |
| 43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.78855593 |
| 44 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.75065306 |
| 45 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.72423343 |
| 46 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.70424940 |
| 47 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.69863411 |
| 48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.67440270 |
| 49 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.62933170 |
| 50 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57679156 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.56604166 |
| 52 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.55791759 |
| 53 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.55676099 |
| 54 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.52572124 |
| 55 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.51897413 |
| 56 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.50602848 |
| 57 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.47303728 |
| 58 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.45186377 |
| 59 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.44911440 |
| 60 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42013265 |
| 61 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.41497598 |
| 62 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.39128357 |
| 63 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.35343982 |
| 64 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.34396325 |
| 65 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.33790654 |
| 66 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.33166397 |
| 67 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.28030222 |
| 68 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.25240535 |
| 69 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.24592764 |
| 70 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.24211655 |
| 71 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.22344189 |
| 72 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.22191187 |
| 73 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.21285763 |
| 74 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.21060101 |
| 75 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.20154890 |
| 76 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.17651938 |
| 77 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.16150542 |
| 78 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.15958867 |
| 79 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.15873345 |
| 80 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15733488 |
| 81 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.14359560 |
| 82 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.11588389 |
| 83 | AR_20517297_ChIP-Seq_VCAP_Human | 1.10723804 |
| 84 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.10082840 |
| 85 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.09976297 |
| 86 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.09651577 |
| 87 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.09367246 |
| 88 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.09306456 |
| 89 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.07337807 |
| 90 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.06609858 |
| 91 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.06006604 |
| 92 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.05153020 |
| 93 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.05153020 |
| 94 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04784014 |
| 95 | ERA_21632823_ChIP-Seq_H3396_Human | 1.04215717 |
| 96 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03821116 |
| 97 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.03609734 |
| 98 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.02464460 |
| 99 | GATA3_26560356_Chip-Seq_TH2_Human | 1.02328404 |
| 100 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99718758 |
| 101 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.99639454 |
| 102 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.98679911 |
| 103 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.98616435 |
| 104 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.97826201 |
| 105 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.95910676 |
| 106 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.95189167 |
| 107 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.94476053 |
| 108 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.94091436 |
| 109 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.93892026 |
| 110 | P300_27268052_Chip-Seq_Bcells_Human | 0.93204936 |
| 111 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.93072691 |
| 112 | EWS_26573619_Chip-Seq_HEK293_Human | 0.92437055 |
| 113 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91236558 |
| 114 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.90496101 |
| 115 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.89590852 |
| 116 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.89106414 |
| 117 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.88184526 |
| 118 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.88060161 |
| 119 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.87872794 |
| 120 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.87731157 |
| 121 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.87597526 |
| 122 | * SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.87142892 |
| 123 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.86960075 |
| 124 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.86718311 |
| 125 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.86103001 |
| 126 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.86011820 |
| 127 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.85927993 |
| 128 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.85841182 |
| 129 | * SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.85398930 |
| 130 | * HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.84346523 |
| 131 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.84199361 |
| 132 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.84191957 |
| 133 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.84004277 |
| 134 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.82842752 |
| 135 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.82547582 |
| 136 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.82289428 |
| 137 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.81074893 |
| 138 | * YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.80334944 |
| 139 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.80143596 |
| 140 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.78829081 |
| 141 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.78018375 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 5.42300293 |
| 2 | MP0004957_abnormal_blastocyst_morpholog | 3.59130755 |
| 3 | MP0003111_abnormal_nucleus_morphology | 3.52543269 |
| 4 | MP0008057_abnormal_DNA_replication | 3.09974855 |
| 5 | MP0010094_abnormal_chromosome_stability | 3.06939815 |
| 6 | MP0003077_abnormal_cell_cycle | 3.04760661 |
| 7 | MP0008058_abnormal_DNA_repair | 2.95888866 |
| 8 | MP0003718_maternal_effect | 2.93779642 |
| 9 | MP0003786_premature_aging | 2.68881885 |
| 10 | MP0003646_muscle_fatigue | 2.68729805 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.47241388 |
| 12 | MP0008007_abnormal_cellular_replicative | 2.39549857 |
| 13 | MP0002736_abnormal_nociception_after | 2.39383982 |
| 14 | MP0005671_abnormal_response_to | 2.35966032 |
| 15 | MP0003186_abnormal_redox_activity | 2.33405422 |
| 16 | MP0008932_abnormal_embryonic_tissue | 2.31699074 |
| 17 | MP0008995_early_reproductive_senescence | 2.29054249 |
| 18 | MP0005646_abnormal_pituitary_gland | 2.29051143 |
| 19 | MP0003195_calcinosis | 2.26813192 |
| 20 | MP0002396_abnormal_hematopoietic_system | 2.26329781 |
| 21 | MP0002132_abnormal_respiratory_system | 2.24191164 |
| 22 | MP0009333_abnormal_splenocyte_physiolog | 2.23830635 |
| 23 | MP0008260_abnormal_autophagy | 2.17666431 |
| 24 | MP0001986_abnormal_taste_sensitivity | 2.13631791 |
| 25 | MP0001968_abnormal_touch/_nociception | 2.11295229 |
| 26 | MP0005084_abnormal_gallbladder_morpholo | 2.11194685 |
| 27 | MP0002102_abnormal_ear_morphology | 2.07913832 |
| 28 | MP0002837_dystrophic_cardiac_calcinosis | 2.06842784 |
| 29 | MP0003763_abnormal_thymus_physiology | 2.06517844 |
| 30 | MP0001835_abnormal_antigen_presentation | 2.03458884 |
| 31 | MP0002653_abnormal_ependyma_morphology | 1.93931353 |
| 32 | MP0003806_abnormal_nucleotide_metabolis | 1.87795305 |
| 33 | MP0008872_abnormal_physiological_respon | 1.86797527 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.83919110 |
| 35 | MP0008875_abnormal_xenobiotic_pharmacok | 1.81887513 |
| 36 | MP0005075_abnormal_melanosome_morpholog | 1.78508540 |
| 37 | MP0003315_abnormal_perineum_morphology | 1.77308249 |
| 38 | MP0002938_white_spotting | 1.72930802 |
| 39 | MP0004142_abnormal_muscle_tone | 1.72124701 |
| 40 | MP0008877_abnormal_DNA_methylation | 1.69511056 |
| 41 | MP0002876_abnormal_thyroid_physiology | 1.56725308 |
| 42 | MP0003011_delayed_dark_adaptation | 1.51027568 |
| 43 | MP0009785_altered_susceptibility_to | 1.50173440 |
| 44 | MP0002163_abnormal_gland_morphology | 1.49917668 |
| 45 | MP0005253_abnormal_eye_physiology | 1.49881747 |
| 46 | MP0004145_abnormal_muscle_electrophysio | 1.45451320 |
| 47 | MP0006036_abnormal_mitochondrial_physio | 1.43612019 |
| 48 | MP0001545_abnormal_hematopoietic_system | 1.38526517 |
| 49 | MP0005397_hematopoietic_system_phenotyp | 1.38526517 |
| 50 | MP0001853_heart_inflammation | 1.38187387 |
| 51 | MP0001529_abnormal_vocalization | 1.37023355 |
| 52 | MP0009764_decreased_sensitivity_to | 1.35737061 |
| 53 | MP0000490_abnormal_crypts_of | 1.34634549 |
| 54 | MP0002277_abnormal_respiratory_mucosa | 1.34015320 |
| 55 | MP0002148_abnormal_hypersensitivity_rea | 1.31687562 |
| 56 | MP0000689_abnormal_spleen_morphology | 1.30775682 |
| 57 | MP0002398_abnormal_bone_marrow | 1.29495701 |
| 58 | MP0009379_abnormal_foot_pigmentation | 1.28652359 |
| 59 | MP0005645_abnormal_hypothalamus_physiol | 1.27914804 |
| 60 | MP0003123_paternal_imprinting | 1.27740292 |
| 61 | MP0002722_abnormal_immune_system | 1.27287180 |
| 62 | MP0006035_abnormal_mitochondrial_morpho | 1.25788814 |
| 63 | MP0005410_abnormal_fertilization | 1.25737549 |
| 64 | MP0001730_embryonic_growth_arrest | 1.24647800 |
| 65 | MP0000372_irregular_coat_pigmentation | 1.23976219 |
| 66 | MP0003941_abnormal_skin_development | 1.23214531 |
| 67 | MP0006072_abnormal_retinal_apoptosis | 1.21071435 |
| 68 | MP0001905_abnormal_dopamine_level | 1.20634687 |
| 69 | MP0004147_increased_porphyrin_level | 1.19748341 |
| 70 | MP0005025_abnormal_response_to | 1.19647921 |
| 71 | MP0000313_abnormal_cell_death | 1.19212353 |
| 72 | MP0001764_abnormal_homeostasis | 1.18914304 |
| 73 | MP0001800_abnormal_humoral_immune | 1.17817862 |
| 74 | MP0004381_abnormal_hair_follicle | 1.17775682 |
| 75 | MP0002420_abnormal_adaptive_immunity | 1.17696564 |
| 76 | MP0002723_abnormal_immune_serum | 1.17449405 |
| 77 | MP0001819_abnormal_immune_cell | 1.16432187 |
| 78 | MP0001542_abnormal_bone_strength | 1.15885029 |
| 79 | MP0003136_yellow_coat_color | 1.14339766 |
| 80 | MP0000716_abnormal_immune_system | 1.14013593 |
| 81 | MP0005332_abnormal_amino_acid | 1.13689375 |
| 82 | MP0005377_hearing/vestibular/ear_phenot | 1.11743541 |
| 83 | MP0003878_abnormal_ear_physiology | 1.11743541 |
| 84 | MP0009046_muscle_twitch | 1.09789283 |
| 85 | MP0002429_abnormal_blood_cell | 1.09464252 |
| 86 | MP0000350_abnormal_cell_proliferation | 1.09247573 |
| 87 | MP0006082_CNS_inflammation | 1.09201803 |
| 88 | MP0002019_abnormal_tumor_incidence | 1.09155120 |
| 89 | MP0001984_abnormal_olfaction | 1.09126198 |
| 90 | MP0005000_abnormal_immune_tolerance | 1.08810812 |
| 91 | MP0004043_abnormal_pH_regulation | 1.07785489 |
| 92 | MP0002452_abnormal_antigen_presenting | 1.07719459 |
| 93 | MP0000015_abnormal_ear_pigmentation | 1.07621911 |
| 94 | MP0002210_abnormal_sex_determination | 1.03425430 |
| 95 | MP0000631_abnormal_neuroendocrine_gland | 1.01659796 |
| 96 | MP0000685_abnormal_immune_system | 1.01411166 |
| 97 | MP0005360_urolithiasis | 1.00325138 |
| 98 | MP0003866_abnormal_defecation | 1.00032820 |
| 99 | MP0000703_abnormal_thymus_morphology | 0.99502532 |
| 100 | MP0006276_abnormal_autonomic_nervous | 0.98834218 |
| 101 | MP0002405_respiratory_system_inflammati | 0.97407149 |
| 102 | MP0005379_endocrine/exocrine_gland_phen | 0.96241489 |
| 103 | MP0005670_abnormal_white_adipose | 0.95873393 |
| 104 | MP0005174_abnormal_tail_pigmentation | 0.95189843 |
| 105 | MP0002095_abnormal_skin_pigmentation | 0.94222741 |
| 106 | MP0000358_abnormal_cell_content/ | 0.93817173 |
| 107 | MP0004133_heterotaxia | 0.90820793 |
| 108 | MP0001929_abnormal_gametogenesis | 0.88163857 |
| 109 | MP0002234_abnormal_pharynx_morphology | 0.87120520 |
| 110 | MP0001145_abnormal_male_reproductive | 0.86858423 |
| 111 | MP0005636_abnormal_mineral_homeostasis | 0.86715678 |
| 112 | MP0000858_altered_metastatic_potential | 0.83967197 |
| 113 | MP0002080_prenatal_lethality | 0.82582606 |
| 114 | MP0005058_abnormal_lysosome_morphology | 0.82277193 |
| 115 | MP0002160_abnormal_reproductive_system | 0.81312195 |
| 116 | MP0005389_reproductive_system_phenotype | 0.80904219 |
| 117 | MP0005171_absent_coat_pigmentation | 0.79660709 |
| 118 | MP0003252_abnormal_bile_duct | 0.79327227 |
| 119 | MP0001324_abnormal_eye_pigmentation | 0.79098527 |
| 120 | MP0001697_abnormal_embryo_size | 0.78938562 |
| 121 | MP0009745_abnormal_behavioral_response | 0.78603816 |
| 122 | MP0003698_abnormal_male_reproductive | 0.77310238 |
| 123 | MP0005395_other_phenotype | 0.77011249 |
| 124 | MP0002419_abnormal_innate_immunity | 0.76970672 |
| 125 | MP0003638_abnormal_response/metabolism_ | 0.75994521 |
| 126 | MP0001661_extended_life_span | 0.75922436 |
| 127 | MP0002638_abnormal_pupillary_reflex | 0.74860952 |
| 128 | MP0005085_abnormal_gallbladder_physiolo | 0.74649258 |
| 129 | MP0005408_hypopigmentation | 0.74389532 |
| 130 | MP0004782_abnormal_surfactant_physiolog | 0.73642446 |
| 131 | MP0001119_abnormal_female_reproductive | 0.73144872 |
| 132 | MP0000653_abnormal_sex_gland | 0.72166996 |
| 133 | MP0008789_abnormal_olfactory_epithelium | 0.71944425 |
| 134 | MP0002733_abnormal_thermal_nociception | 0.71925768 |
| 135 | MP0003724_increased_susceptibility_to | 0.71500045 |
| 136 | MP0000013_abnormal_adipose_tissue | 0.71126554 |
| 137 | MP0002693_abnormal_pancreas_physiology | 0.70459014 |
| 138 | MP0002090_abnormal_vision | 0.69985356 |
| 139 | MP0005083_abnormal_biliary_tract | 0.69229858 |
| 140 | MP0001919_abnormal_reproductive_system | 0.68959438 |
| 141 | MP0002928_abnormal_bile_duct | 0.68723379 |
| 142 | MP0000749_muscle_degeneration | 0.68090880 |
| 143 | MP0001486_abnormal_startle_reflex | 0.67907925 |
| 144 | MP0005451_abnormal_body_composition | 0.67294328 |
| 145 | MP0005386_behavior/neurological_phenoty | 0.66553735 |
| 146 | MP0004924_abnormal_behavior | 0.66553735 |
| 147 | MP0002735_abnormal_chemical_nociception | 0.65155871 |
| 148 | MP0001970_abnormal_pain_threshold | 0.64969080 |
| 149 | MP0000026_abnormal_inner_ear | 0.64399730 |
| 150 | MP0000566_synostosis | 0.64233024 |
| 151 | MP0001790_abnormal_immune_system | 0.63641632 |
| 152 | MP0005387_immune_system_phenotype | 0.63641632 |
| 153 | MP0003656_abnormal_erythrocyte_physiolo | 0.63216743 |
| 154 | MP0000681_abnormal_thyroid_gland | 0.62681393 |
| 155 | MP0009697_abnormal_copulation | 0.61856327 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Cerebral hypomyelination (HP:0006808) | 4.73366243 |
| 2 | Birth length less than 3rd percentile (HP:0003561) | 4.09385509 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.01659955 |
| 4 | Abnormal number of erythroid precursors (HP:0012131) | 4.00570862 |
| 5 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.84909612 |
| 6 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.67447660 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 3.66165599 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.64649672 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.62527437 |
| 10 | Breast hypoplasia (HP:0003187) | 3.59331517 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.52889915 |
| 12 | Rough bone trabeculation (HP:0100670) | 3.42424100 |
| 13 | Carpal bone hypoplasia (HP:0001498) | 3.33213242 |
| 14 | Type I transferrin isoform profile (HP:0003642) | 3.32478921 |
| 15 | Hepatic necrosis (HP:0002605) | 3.26260533 |
| 16 | Increased CSF lactate (HP:0002490) | 3.24389714 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.21474366 |
| 18 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.19241949 |
| 19 | Acute necrotizing encephalopathy (HP:0006965) | 3.13382750 |
| 20 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.12119418 |
| 21 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.12119418 |
| 22 | Increased serum lactate (HP:0002151) | 3.08380516 |
| 23 | Pancreatic cysts (HP:0001737) | 3.02510527 |
| 24 | Exertional dyspnea (HP:0002875) | 3.01718436 |
| 25 | Molar tooth sign on MRI (HP:0002419) | 3.01193961 |
| 26 | Abnormality of midbrain morphology (HP:0002418) | 3.01193961 |
| 27 | Type II lissencephaly (HP:0007260) | 2.93315388 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.90727644 |
| 29 | Oral leukoplakia (HP:0002745) | 2.90289212 |
| 30 | CNS hypomyelination (HP:0003429) | 2.82157683 |
| 31 | Renal Fanconi syndrome (HP:0001994) | 2.82110583 |
| 32 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.81249141 |
| 33 | Constricted visual fields (HP:0001133) | 2.79313886 |
| 34 | Aplastic anemia (HP:0001915) | 2.77415773 |
| 35 | Optic disc pallor (HP:0000543) | 2.74271071 |
| 36 | Reticulocytopenia (HP:0001896) | 2.73278160 |
| 37 | True hermaphroditism (HP:0010459) | 2.72085653 |
| 38 | Respiratory difficulties (HP:0002880) | 2.69847323 |
| 39 | Premature graying of hair (HP:0002216) | 2.68827867 |
| 40 | Progressive microcephaly (HP:0000253) | 2.67270529 |
| 41 | Cerebral edema (HP:0002181) | 2.66774778 |
| 42 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.66460561 |
| 43 | Patellar aplasia (HP:0006443) | 2.59265537 |
| 44 | Increased intramyocellular lipid droplets (HP:0012240) | 2.57987988 |
| 45 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.56003030 |
| 46 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.55520105 |
| 47 | Medial flaring of the eyebrow (HP:0010747) | 2.55386253 |
| 48 | Congenital stationary night blindness (HP:0007642) | 2.54711770 |
| 49 | Sparse eyelashes (HP:0000653) | 2.53374664 |
| 50 | Attenuation of retinal blood vessels (HP:0007843) | 2.53103836 |
| 51 | Generalized aminoaciduria (HP:0002909) | 2.52310822 |
| 52 | Abnormal trabecular bone morphology (HP:0100671) | 2.51797964 |
| 53 | Type 2 muscle fiber atrophy (HP:0003554) | 2.51081260 |
| 54 | Degeneration of anterior horn cells (HP:0002398) | 2.50463793 |
| 55 | Abnormality of the anterior horn cell (HP:0006802) | 2.50463793 |
| 56 | Macrocytic anemia (HP:0001972) | 2.49166633 |
| 57 | Hyperglycinemia (HP:0002154) | 2.45788449 |
| 58 | IgG deficiency (HP:0004315) | 2.42825149 |
| 59 | Progressive macrocephaly (HP:0004481) | 2.39912904 |
| 60 | Lactic acidosis (HP:0003128) | 2.39602384 |
| 61 | Muscle fiber atrophy (HP:0100295) | 2.36955617 |
| 62 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.35640807 |
| 63 | Microretrognathia (HP:0000308) | 2.34459313 |
| 64 | Acute encephalopathy (HP:0006846) | 2.33296456 |
| 65 | IgM deficiency (HP:0002850) | 2.33006659 |
| 66 | Abolished electroretinogram (ERG) (HP:0000550) | 2.26287096 |
| 67 | Exercise intolerance (HP:0003546) | 2.25996655 |
| 68 | Secondary amenorrhea (HP:0000869) | 2.23975231 |
| 69 | Methylmalonic aciduria (HP:0012120) | 2.23703329 |
| 70 | Poor head control (HP:0002421) | 2.22058592 |
| 71 | Lethargy (HP:0001254) | 2.21890337 |
| 72 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.21450221 |
| 73 | Petechiae (HP:0000967) | 2.20992811 |
| 74 | Cleft eyelid (HP:0000625) | 2.19589611 |
| 75 | Abnormality of the umbilical cord (HP:0010881) | 2.19017334 |
| 76 | Pancytopenia (HP:0001876) | 2.17358843 |
| 77 | CNS demyelination (HP:0007305) | 2.16866010 |
| 78 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.16092237 |
| 79 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.16092237 |
| 80 | Abnormal protein glycosylation (HP:0012346) | 2.16092237 |
| 81 | Abnormal glycosylation (HP:0012345) | 2.16092237 |
| 82 | Bone marrow hypocellularity (HP:0005528) | 2.16072556 |
| 83 | Increased muscle lipid content (HP:0009058) | 2.15885248 |
| 84 | Progressive muscle weakness (HP:0003323) | 2.15871749 |
| 85 | Retinal dysplasia (HP:0007973) | 2.15172170 |
| 86 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.13441200 |
| 87 | Stomatitis (HP:0010280) | 2.13347116 |
| 88 | Microvesicular hepatic steatosis (HP:0001414) | 2.12838514 |
| 89 | Multiple enchondromatosis (HP:0005701) | 2.11092860 |
| 90 | Nephronophthisis (HP:0000090) | 2.11061773 |
| 91 | Prolonged neonatal jaundice (HP:0006579) | 2.11053154 |
| 92 | Pallor (HP:0000980) | 2.11001281 |
| 93 | Emotional lability (HP:0000712) | 2.08201891 |
| 94 | Trismus (HP:0000211) | 2.06335668 |
| 95 | Renal cortical cysts (HP:0000803) | 2.05941624 |
| 96 | Premature ovarian failure (HP:0008209) | 2.05517922 |
| 97 | Respiratory failure (HP:0002878) | 2.04728924 |
| 98 | Short tibia (HP:0005736) | 2.04319895 |
| 99 | Hypoplasia of the radius (HP:0002984) | 2.03020012 |
| 100 | Death in infancy (HP:0001522) | 2.02582379 |
| 101 | Dicarboxylic aciduria (HP:0003215) | 2.02098279 |
| 102 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.02098279 |
| 103 | Abnormality of the preputium (HP:0100587) | 2.01904501 |
| 104 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.01362524 |
| 105 | Nephrogenic diabetes insipidus (HP:0009806) | 2.00676917 |
| 106 | Congenital primary aphakia (HP:0007707) | 2.00586121 |
| 107 | Abnormality of the renal cortex (HP:0011035) | 1.99852382 |
| 108 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.98150028 |
| 109 | Glycosuria (HP:0003076) | 1.98033962 |
| 110 | Abnormality of urine glucose concentration (HP:0011016) | 1.98033962 |
| 111 | Ketoacidosis (HP:0001993) | 1.97931230 |
| 112 | Cellular immunodeficiency (HP:0005374) | 1.97758255 |
| 113 | Cerebellar dysplasia (HP:0007033) | 1.96633197 |
| 114 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.96223471 |
| 115 | Absent radius (HP:0003974) | 1.96156447 |
| 116 | Aplasia involving forearm bones (HP:0009822) | 1.95268007 |
| 117 | Absent forearm bone (HP:0003953) | 1.95268007 |
| 118 | Gait imbalance (HP:0002141) | 1.92879996 |
| 119 | Methylmalonic acidemia (HP:0002912) | 1.92049831 |
| 120 | Abnormality of serum amino acid levels (HP:0003112) | 1.91743874 |
| 121 | Delusions (HP:0000746) | 1.90606724 |
| 122 | Abnormality of renal resorption (HP:0011038) | 1.90157648 |
| 123 | Lymphoma (HP:0002665) | 1.90045823 |
| 124 | Hyperalaninemia (HP:0003348) | 1.88711832 |
| 125 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.88711832 |
| 126 | Abnormality of alanine metabolism (HP:0010916) | 1.88711832 |
| 127 | Abnormality of glycolysis (HP:0004366) | 1.88414311 |
| 128 | Increased serum pyruvate (HP:0003542) | 1.88414311 |
| 129 | Split foot (HP:0001839) | 1.87460073 |
| 130 | Tongue fasciculations (HP:0001308) | 1.87337994 |
| 131 | Granulocytopenia (HP:0001913) | 1.86139818 |
| 132 | Abnormal spermatogenesis (HP:0008669) | 1.84977265 |
| 133 | Sclerocornea (HP:0000647) | 1.84603158 |
| 134 | Ketosis (HP:0001946) | 1.83386760 |
| 135 | Reduced antithrombin III activity (HP:0001976) | 1.83214381 |
| 136 | Stenosis of the external auditory canal (HP:0000402) | 1.83087723 |
| 137 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.82293303 |
| 138 | Absent thumb (HP:0009777) | 1.79928104 |
| 139 | Pendular nystagmus (HP:0012043) | 1.78887219 |
| 140 | Abnormality of the ileum (HP:0001549) | 1.78671378 |
| 141 | Inability to walk (HP:0002540) | 1.78286841 |
| 142 | Increased IgM level (HP:0003496) | 1.77784592 |
| 143 | Meckel diverticulum (HP:0002245) | 1.77747425 |
| 144 | Opisthotonus (HP:0002179) | 1.77352498 |
| 145 | Hypomagnesemia (HP:0002917) | 1.76315742 |
| 146 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.74752885 |
| 147 | Concave nail (HP:0001598) | 1.74093471 |
| 148 | Abnormal drinking behavior (HP:0030082) | 1.73221027 |
| 149 | Polydipsia (HP:0001959) | 1.73221027 |
| 150 | Neutropenia (HP:0001875) | 1.69753154 |
| 151 | Decreased central vision (HP:0007663) | 1.69263193 |
| 152 | Leukodystrophy (HP:0002415) | 1.68201445 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 5.23075166 |
| 2 | STK16 | 4.28142973 |
| 3 | WEE1 | 3.62445494 |
| 4 | VRK2 | 3.62021557 |
| 5 | MAP4K2 | 3.47251497 |
| 6 | NME2 | 3.36461810 |
| 7 | EIF2AK1 | 2.82335837 |
| 8 | PLK4 | 2.66498514 |
| 9 | FRK | 2.50477896 |
| 10 | TESK2 | 2.47129635 |
| 11 | NUAK1 | 2.46897077 |
| 12 | IRAK3 | 2.29733657 |
| 13 | TSSK6 | 2.23074916 |
| 14 | PIM2 | 2.19197841 |
| 15 | SRPK1 | 2.17070878 |
| 16 | TAOK3 | 2.10401591 |
| 17 | EIF2AK3 | 2.07928719 |
| 18 | INSRR | 2.03360331 |
| 19 | VRK1 | 2.01868179 |
| 20 | ZAK | 1.77780773 |
| 21 | ARAF | 1.59720818 |
| 22 | GRK1 | 1.58273941 |
| 23 | KDR | 1.57266840 |
| 24 | IRAK4 | 1.55085291 |
| 25 | BRSK2 | 1.54072874 |
| 26 | TRIM28 | 1.53229313 |
| 27 | MST4 | 1.52022258 |
| 28 | TXK | 1.47757194 |
| 29 | ACVR1B | 1.47377503 |
| 30 | CCNB1 | 1.44134075 |
| 31 | PLK1 | 1.42502721 |
| 32 | MAP4K1 | 1.41385058 |
| 33 | NME1 | 1.38639268 |
| 34 | PBK | 1.36860970 |
| 35 | MKNK1 | 1.32727691 |
| 36 | BMPR1B | 1.31529421 |
| 37 | PINK1 | 1.28635856 |
| 38 | BRSK1 | 1.20747813 |
| 39 | WNK3 | 1.20407848 |
| 40 | DYRK3 | 1.19549678 |
| 41 | AKT3 | 1.16880510 |
| 42 | CSNK1A1L | 1.14117812 |
| 43 | MKNK2 | 1.13685568 |
| 44 | PLK3 | 1.12176874 |
| 45 | TTK | 1.11209854 |
| 46 | NEK2 | 1.10558662 |
| 47 | AURKA | 1.09491605 |
| 48 | BRAF | 1.08800588 |
| 49 | TLK1 | 1.08596213 |
| 50 | CSNK1G1 | 1.08432771 |
| 51 | CSNK1G2 | 1.06160850 |
| 52 | EPHA2 | 1.03525725 |
| 53 | TIE1 | 1.01563165 |
| 54 | MAP3K11 | 1.00987081 |
| 55 | AURKB | 1.00210441 |
| 56 | MAP2K7 | 0.99549438 |
| 57 | MAPK13 | 0.95389024 |
| 58 | DYRK2 | 0.93458556 |
| 59 | CDC7 | 0.93116627 |
| 60 | PDK2 | 0.93027297 |
| 61 | TESK1 | 0.92588481 |
| 62 | EIF2AK2 | 0.91016669 |
| 63 | ADRBK1 | 0.88123108 |
| 64 | NEK1 | 0.86153420 |
| 65 | MAP3K12 | 0.84159042 |
| 66 | MAPKAPK3 | 0.83969274 |
| 67 | MUSK | 0.81558808 |
| 68 | MAP3K4 | 0.81164407 |
| 69 | PHKG1 | 0.79922556 |
| 70 | PHKG2 | 0.79922556 |
| 71 | LIMK1 | 0.79539469 |
| 72 | DAPK1 | 0.79157594 |
| 73 | KIT | 0.76799097 |
| 74 | IKBKB | 0.76438630 |
| 75 | PKN1 | 0.76218119 |
| 76 | CDK7 | 0.75901473 |
| 77 | BCKDK | 0.75332664 |
| 78 | PRKCI | 0.74659715 |
| 79 | GRK5 | 0.73225724 |
| 80 | OXSR1 | 0.73159083 |
| 81 | RPS6KB2 | 0.72002081 |
| 82 | CHEK2 | 0.71827785 |
| 83 | CSNK2A1 | 0.69778849 |
| 84 | BLK | 0.69434411 |
| 85 | ATR | 0.68137374 |
| 86 | GRK6 | 0.67890273 |
| 87 | PIM1 | 0.67377584 |
| 88 | IRAK1 | 0.64806814 |
| 89 | PRKCQ | 0.63218688 |
| 90 | IRAK2 | 0.62739992 |
| 91 | RPS6KA5 | 0.61561766 |
| 92 | CDK8 | 0.61552257 |
| 93 | RPS6KA4 | 0.60939505 |
| 94 | PASK | 0.60615420 |
| 95 | GRK7 | 0.60554079 |
| 96 | MYLK | 0.59805045 |
| 97 | NEK6 | 0.59326868 |
| 98 | ADRBK2 | 0.59048917 |
| 99 | PAK1 | 0.58804778 |
| 100 | OBSCN | 0.58663308 |
| 101 | STK24 | 0.56329529 |
| 102 | TBK1 | 0.56292807 |
| 103 | ZAP70 | 0.55916568 |
| 104 | CSNK2A2 | 0.54949729 |
| 105 | CSNK1G3 | 0.54756398 |
| 106 | DAPK3 | 0.52093305 |
| 107 | MAP3K8 | 0.51327127 |
| 108 | MARK3 | 0.51236342 |
| 109 | PAK4 | 0.51042370 |
| 110 | ABL2 | 0.49939812 |
| 111 | PAK3 | 0.49596963 |
| 112 | PTK2B | 0.48798797 |
| 113 | EPHA3 | 0.48197950 |
| 114 | CSNK1A1 | 0.48127722 |
| 115 | IKBKE | 0.47997898 |
| 116 | STK4 | 0.43916761 |
| 117 | PRKCE | 0.43666640 |
| 118 | TEC | 0.42851934 |
| 119 | LYN | 0.42769024 |
| 120 | CDK3 | 0.42349097 |
| 121 | WNK4 | 0.41391501 |
| 122 | CLK1 | 0.39374693 |
| 123 | ITK | 0.39331556 |
| 124 | MAPKAPK5 | 0.39034134 |
| 125 | TNK2 | 0.38889391 |
| 126 | ILK | 0.37881551 |
| 127 | CHEK1 | 0.37538516 |
| 128 | MATK | 0.37056050 |
| 129 | MAP2K6 | 0.37049916 |
| 130 | NEK9 | 0.37044788 |
| 131 | YES1 | 0.36993733 |
| 132 | BTK | 0.36877291 |
| 133 | TAF1 | 0.36224759 |
| 134 | FES | 0.36165662 |
| 135 | TAOK2 | 0.35841890 |
| 136 | CDK19 | 0.34921253 |
| 137 | SYK | 0.34747874 |
| 138 | LCK | 0.34318748 |
| 139 | SIK3 | 0.33689667 |
| 140 | PRKACA | 0.32790391 |
| 141 | CAMK2G | 0.31947138 |
| 142 | BCR | 0.31195414 |
| 143 | PIK3CG | 0.31087959 |
| 144 | MAP2K3 | 0.30921990 |
| 145 | MAP3K3 | 0.30633916 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.89438677 |
| 2 | RNA polymerase_Homo sapiens_hsa03020 | 4.39231590 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 4.06857692 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 3.79430751 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 3.26820781 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.18725775 |
| 7 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.84705494 |
| 8 | Base excision repair_Homo sapiens_hsa03410 | 2.63319289 |
| 9 | Spliceosome_Homo sapiens_hsa03040 | 2.63097019 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.53999260 |
| 11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.48845242 |
| 12 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.31158487 |
| 13 | RNA transport_Homo sapiens_hsa03013 | 2.30822578 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.14246367 |
| 15 | Protein export_Homo sapiens_hsa03060 | 2.08273695 |
| 16 | Parkinsons disease_Homo sapiens_hsa05012 | 2.06741749 |
| 17 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.98603650 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.84474513 |
| 19 | Purine metabolism_Homo sapiens_hsa00230 | 1.75395290 |
| 20 | Huntingtons disease_Homo sapiens_hsa05016 | 1.69553641 |
| 21 | Cell cycle_Homo sapiens_hsa04110 | 1.63415604 |
| 22 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.61318873 |
| 23 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.53358858 |
| 24 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.45039510 |
| 25 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.43434572 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.43427986 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.40135837 |
| 28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.38580079 |
| 29 | Peroxisome_Homo sapiens_hsa04146 | 1.37742928 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.33030409 |
| 31 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.30778320 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.30019841 |
| 33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.28177249 |
| 34 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.27066149 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.26849823 |
| 36 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.25843257 |
| 37 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.25491151 |
| 38 | Alzheimers disease_Homo sapiens_hsa05010 | 1.21234772 |
| 39 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.17407133 |
| 40 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.12645005 |
| 41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.11657232 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.10667968 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.08755628 |
| 44 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.07927222 |
| 45 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.06279235 |
| 46 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.05488931 |
| 47 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.04428077 |
| 48 | Sulfur relay system_Homo sapiens_hsa04122 | 0.97054593 |
| 49 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.96597366 |
| 50 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.93581633 |
| 51 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.92485953 |
| 52 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.91437971 |
| 53 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.89250639 |
| 54 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.88816979 |
| 55 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.87743957 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.87292954 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.86276341 |
| 58 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.86114357 |
| 59 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.84308701 |
| 60 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.82419850 |
| 61 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.80953112 |
| 62 | Allograft rejection_Homo sapiens_hsa05330 | 0.79966177 |
| 63 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.78364587 |
| 64 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.77210115 |
| 65 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.70003461 |
| 66 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.67449683 |
| 67 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.67293915 |
| 68 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.66150677 |
| 69 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.65301399 |
| 70 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65222835 |
| 71 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64732601 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.63150829 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62660123 |
| 74 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61063741 |
| 75 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.60304476 |
| 76 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.59547158 |
| 77 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.57805552 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.57048874 |
| 79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.56530809 |
| 80 | Other glycan degradation_Homo sapiens_hsa00511 | 0.56104551 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.55257575 |
| 82 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.53540779 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52740095 |
| 84 | Phototransduction_Homo sapiens_hsa04744 | 0.52411372 |
| 85 | Measles_Homo sapiens_hsa05162 | 0.47757857 |
| 86 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.46383227 |
| 87 | Galactose metabolism_Homo sapiens_hsa00052 | 0.45431254 |
| 88 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.45266510 |
| 89 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.45102683 |
| 90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43613652 |
| 91 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.42471082 |
| 92 | Asthma_Homo sapiens_hsa05310 | 0.41652860 |
| 93 | Legionellosis_Homo sapiens_hsa05134 | 0.41123677 |
| 94 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.40984222 |
| 95 | Retinol metabolism_Homo sapiens_hsa00830 | 0.40611918 |
| 96 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40333298 |
| 97 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.39756089 |
| 98 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.39484361 |
| 99 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.39268444 |
| 100 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.38456636 |
| 101 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.38386640 |
| 102 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.37388940 |
| 103 | Shigellosis_Homo sapiens_hsa05131 | 0.37138281 |
| 104 | Alcoholism_Homo sapiens_hsa05034 | 0.36711838 |
| 105 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.34914410 |
| 106 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.34025462 |
| 107 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.33927692 |
| 108 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.33632744 |
| 109 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.33535981 |
| 110 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.32930431 |
| 111 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.32445633 |
| 112 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.32300467 |
| 113 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.29816888 |
| 114 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.28638872 |
| 115 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.26918882 |
| 116 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.26631010 |
| 117 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.26498707 |
| 118 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.26159486 |
| 119 | Carbon metabolism_Homo sapiens_hsa01200 | 0.24508187 |
| 120 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.24249845 |
| 121 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.23907636 |
| 122 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.23749471 |
| 123 | Lysosome_Homo sapiens_hsa04142 | 0.23100170 |
| 124 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.22146069 |
| 125 | Apoptosis_Homo sapiens_hsa04210 | 0.21671967 |
| 126 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.19620329 |
| 127 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.19513082 |
| 128 | HTLV-I infection_Homo sapiens_hsa05166 | 0.19225342 |
| 129 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.18311905 |
| 130 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.16288009 |
| 131 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.15759274 |
| 132 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.14911924 |
| 133 | Leishmaniasis_Homo sapiens_hsa05140 | 0.11621287 |
| 134 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.08676725 |
| 135 | Influenza A_Homo sapiens_hsa05164 | 0.08257543 |

