ZMYM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane organization (GO:0097090)5.62278248
2regulation of telomere maintenance via telomerase (GO:0032210)5.12080481
3presynaptic membrane assembly (GO:0097105)4.72641714
4maturation of 5.8S rRNA (GO:0000460)4.38546013
5mitotic metaphase plate congression (GO:0007080)4.37108712
6regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.35467954
7nuclear pore organization (GO:0006999)4.08147331
8regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.94807405
9regulation of mitotic spindle checkpoint (GO:1903504)3.94807405
10replication fork processing (GO:0031297)3.92969268
11mitotic sister chromatid cohesion (GO:0007064)3.82580677
12metaphase plate congression (GO:0051310)3.77296515
13DNA ligation (GO:0006266)3.75662961
14mitotic sister chromatid segregation (GO:0000070)3.72826151
15resolution of meiotic recombination intermediates (GO:0000712)3.72391385
16nuclear pore complex assembly (GO:0051292)3.71565087
17purine nucleobase biosynthetic process (GO:0009113)3.68266600
18negative regulation of DNA recombination (GO:0045910)3.66750289
19nucleobase biosynthetic process (GO:0046112)3.66354314
20DNA replication initiation (GO:0006270)3.65605437
21double-strand break repair via nonhomologous end joining (GO:0006303)3.61749073
22non-recombinational repair (GO:0000726)3.61749073
23protein localization to kinetochore (GO:0034501)3.61189567
24protein K6-linked ubiquitination (GO:0085020)3.57203516
25DNA replication checkpoint (GO:0000076)3.51710860
26sister chromatid segregation (GO:0000819)3.48495000
27establishment of chromosome localization (GO:0051303)3.42993314
28maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.40796712
29somatic hypermutation of immunoglobulin genes (GO:0016446)3.40734020
30somatic diversification of immune receptors via somatic mutation (GO:0002566)3.40734020
31ribosome assembly (GO:0042255)3.40462318
32rRNA modification (GO:0000154)3.39762932
33spindle checkpoint (GO:0031577)3.38953051
34establishment of integrated proviral latency (GO:0075713)3.38658774
35negative regulation of chromosome segregation (GO:0051985)3.38114187
36negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.35887998
37negative regulation of sister chromatid segregation (GO:0033046)3.35887998
38negative regulation of mitotic sister chromatid separation (GO:2000816)3.35887998
39negative regulation of mitotic sister chromatid segregation (GO:0033048)3.35887998
40regulation of mitotic spindle organization (GO:0060236)3.34224991
41DNA catabolic process, exonucleolytic (GO:0000738)3.33330712
42mitotic nuclear envelope disassembly (GO:0007077)3.32723541
43mitotic spindle checkpoint (GO:0071174)3.32110011
44mitotic spindle assembly checkpoint (GO:0007094)3.32044302
45spindle assembly checkpoint (GO:0071173)3.31463198
46mitotic G2/M transition checkpoint (GO:0044818)3.29473836
47regulation of helicase activity (GO:0051095)3.29135730
48negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.28235565
49regulation of nuclear cell cycle DNA replication (GO:0033262)3.27718918
50regulation of meiosis I (GO:0060631)3.27530772
51DNA replication-dependent nucleosome assembly (GO:0006335)3.26053605
52DNA replication-dependent nucleosome organization (GO:0034723)3.26053605
53ribosome biogenesis (GO:0042254)3.22333477
54negative regulation of meiosis (GO:0045835)3.22115127
55regulation of DNA endoreduplication (GO:0032875)3.19735185
56rRNA methylation (GO:0031167)3.18149771
57DNA double-strand break processing (GO:0000729)3.16444495
58synapsis (GO:0007129)3.14966994
59chromosome segregation (GO:0007059)3.14036287
60regulation of mitotic sister chromatid separation (GO:0010965)3.13365842
61regulation of mitotic sister chromatid segregation (GO:0033047)3.13365842
62regulation of sister chromatid segregation (GO:0033045)3.13365842
63regulation of mitotic metaphase/anaphase transition (GO:0030071)3.13056955
64DNA topological change (GO:0006265)3.12927632
65regulation of chromosome segregation (GO:0051983)3.12724202
66histone H3-K9 demethylation (GO:0033169)3.12316441
67negative regulation of gene silencing (GO:0060969)3.11310885
68membrane disassembly (GO:0030397)3.08509530
69nuclear envelope disassembly (GO:0051081)3.08509530
70regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.07662599
71regulation of centrosome duplication (GO:0010824)3.06560259
72mitotic recombination (GO:0006312)3.06484857
73chromatin remodeling at centromere (GO:0031055)3.05088627
74IMP biosynthetic process (GO:0006188)3.04036865
75negative regulation of mitosis (GO:0045839)3.03639310
76postreplication repair (GO:0006301)3.03454142
77regulation of telomere maintenance (GO:0032204)3.02339731
78response to X-ray (GO:0010165)3.00709797
79histone-serine phosphorylation (GO:0035404)3.00542072
80regulation of centrosome cycle (GO:0046605)2.98705853
81histone mRNA metabolic process (GO:0008334)2.98237825
82DNA strand elongation involved in DNA replication (GO:0006271)2.97460881
83CENP-A containing nucleosome assembly (GO:0034080)2.97418083
84histone arginine methylation (GO:0034969)2.97128599
85positive regulation of mitotic sister chromatid separation (GO:1901970)2.95969232
86positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.95969232
87positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.95969232
88centriole replication (GO:0007099)2.95428214
89positive regulation of chromosome segregation (GO:0051984)2.94293057
90kinetochore organization (GO:0051383)2.93139279
91peptidyl-arginine omega-N-methylation (GO:0035247)2.91250847
92regulation of transcription from RNA polymerase I promoter (GO:0006356)2.90756210
93protein localization to chromosome (GO:0034502)2.90746636
94microtubule depolymerization (GO:0007019)2.89059316
95nucleus organization (GO:0006997)2.88618314
96DNA synthesis involved in DNA repair (GO:0000731)2.88615250
97intra-S DNA damage checkpoint (GO:0031573)2.88236257
98mitotic chromosome condensation (GO:0007076)2.88168334
99ventricular cardiac muscle cell development (GO:0055015)2.87650632
100regulation of centriole replication (GO:0046599)2.87611883
101attachment of spindle microtubules to kinetochore (GO:0008608)2.85550535
102meiotic chromosome segregation (GO:0045132)2.85001608
103telomere maintenance via semi-conservative replication (GO:0032201)2.84734049
104protein deneddylation (GO:0000338)2.83785994
105negative regulation of DNA-dependent DNA replication (GO:2000104)2.83517989
106DNA unwinding involved in DNA replication (GO:0006268)2.82567918
107ATP-dependent chromatin remodeling (GO:0043044)2.82466020
108pore complex assembly (GO:0046931)2.81881322
109regulation of spindle organization (GO:0090224)2.81821724
110mitochondrial RNA metabolic process (GO:0000959)2.80523786
111DNA strand elongation (GO:0022616)2.79622255
112histone exchange (GO:0043486)2.79040603
113mismatch repair (GO:0006298)2.78548859
114regulation of gene silencing by RNA (GO:0060966)2.75645256
115regulation of posttranscriptional gene silencing (GO:0060147)2.75645256
116regulation of gene silencing by miRNA (GO:0060964)2.75645256
117protein localization to chromosome, centromeric region (GO:0071459)2.74998630
118transcription-coupled nucleotide-excision repair (GO:0006283)2.74810022
119nucleotide-excision repair, DNA gap filling (GO:0006297)2.74077606
120cullin deneddylation (GO:0010388)2.73955137
121histone H3-K36 demethylation (GO:0070544)2.73740566
122transcription elongation from RNA polymerase I promoter (GO:0006362)2.73078552
1237-methylguanosine mRNA capping (GO:0006370)2.72549799
124kinetochore assembly (GO:0051382)2.71887717
125RNA capping (GO:0036260)2.71562206
1267-methylguanosine RNA capping (GO:0009452)2.71562206
127telomere maintenance via recombination (GO:0000722)2.71045687
128spliceosomal complex assembly (GO:0000245)2.70280657
129positive regulation of viral genome replication (GO:0045070)2.70053394
130regulation of chromatin silencing (GO:0031935)2.69606891
131DNA replication-independent nucleosome assembly (GO:0006336)2.69223243
132DNA replication-independent nucleosome organization (GO:0034724)2.69223243
133regulation of mitochondrial translation (GO:0070129)2.68900896
134spindle assembly involved in mitosis (GO:0090307)2.68794915

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.87693742
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.72774030
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.71783957
4MYC_18555785_ChIP-Seq_MESCs_Mouse3.18041227
5* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.90683660
6SALL1_21062744_ChIP-ChIP_HESCs_Human2.87853467
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.50741687
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.46300317
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.39800466
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.36182655
11YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.33786298
12MYC_19030024_ChIP-ChIP_MESCs_Mouse2.31099607
13EZH2_22144423_ChIP-Seq_EOC_Human2.25393925
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.21439044
15MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.18132490
16GBX2_23144817_ChIP-Seq_PC3_Human2.13901031
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.13837583
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.11390496
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.11081373
20POU3F2_20337985_ChIP-ChIP_501MEL_Human2.09629828
21ETS1_20019798_ChIP-Seq_JURKAT_Human2.09417837
22JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.07476595
23THAP11_20581084_ChIP-Seq_MESCs_Mouse2.07176193
24ZNF274_21170338_ChIP-Seq_K562_Hela2.06721732
25KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.06453145
26KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.06453145
27KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.06453145
28POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.03040916
29NANOG_18555785_ChIP-Seq_MESCs_Mouse2.01458977
30E2F1_21310950_ChIP-Seq_MCF-7_Human2.00561637
31AR_21909140_ChIP-Seq_LNCAP_Human1.94211328
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.88811793
33* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.88552855
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.86645511
35GABP_17652178_ChIP-ChIP_JURKAT_Human1.85580756
36MYC_18358816_ChIP-ChIP_MESCs_Mouse1.83228720
37* NELFA_20434984_ChIP-Seq_ESCs_Mouse1.80939750
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.79138086
39BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.78059568
40FUS_26573619_Chip-Seq_HEK293_Human1.76223131
41TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.69286393
42HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.67334259
43SOX2_18555785_ChIP-Seq_MESCs_Mouse1.63609808
44FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.61240007
45SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.60948539
46VDR_22108803_ChIP-Seq_LS180_Human1.60040296
47CREB1_15753290_ChIP-ChIP_HEK293T_Human1.59857529
48YY1_21170310_ChIP-Seq_MESCs_Mouse1.59815120
49CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.58944341
50POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.58605468
51NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.57388241
52NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.56657031
53IGF1R_20145208_ChIP-Seq_DFB_Human1.56381472
54FOXP3_21729870_ChIP-Seq_TREG_Human1.55201858
55VDR_23849224_ChIP-Seq_CD4+_Human1.54430022
56TAF15_26573619_Chip-Seq_HEK293_Human1.53430370
57NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.51622029
58FLI1_27457419_Chip-Seq_LIVER_Mouse1.50661858
59POU5F1_16153702_ChIP-ChIP_HESCs_Human1.50294765
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.49342654
61CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.49263015
62* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.46867885
63NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.43915164
64* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.42884702
65TP63_19390658_ChIP-ChIP_HaCaT_Human1.39754754
66GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38928355
67ELK1_19687146_ChIP-ChIP_HELA_Human1.38568362
68SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.36430330
69P300_19829295_ChIP-Seq_ESCs_Human1.33150640
70ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.32684027
71EWS_26573619_Chip-Seq_HEK293_Human1.31723142
72XRN2_22483619_ChIP-Seq_HELA_Human1.29967495
73* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.29555907
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.27508683
75TTF2_22483619_ChIP-Seq_HELA_Human1.26469476
76ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.26321515
77CIITA_25753668_ChIP-Seq_RAJI_Human1.22962298
78DCP1A_22483619_ChIP-Seq_HELA_Human1.20614547
79RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.19911614
80* GABP_19822575_ChIP-Seq_HepG2_Human1.18814895
81SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.18637792
82RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.17571708
83HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.17460050
84* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.16543284
85HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.16327533
86PCGF2_27294783_Chip-Seq_ESCs_Mouse1.15347144
87EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.15165340
88SOX2_16153702_ChIP-ChIP_HESCs_Human1.13929833
89SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12493641
90NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.09198404
91SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.08075358
92AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.07235846
93SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.04925266
94* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.04654957
95* SRF_21415370_ChIP-Seq_HL-1_Mouse1.04173089
96CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.04142586
97EZH2_27294783_Chip-Seq_NPCs_Mouse1.03084410
98SMAD_19615063_ChIP-ChIP_OVARY_Human1.01999478
99SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.01328732
100IRF1_19129219_ChIP-ChIP_H3396_Human1.00389870
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.00105404
102CTBP2_25329375_ChIP-Seq_LNCAP_Human0.98094934
103PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.97816518
104MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.96343286
105POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.96116541
106* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.96004598
107ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.95815125
108NANOG_21062744_ChIP-ChIP_HESCs_Human0.95727868
109SOX17_20123909_ChIP-Seq_XEN_Mouse0.95535389
110KDM5A_27292631_Chip-Seq_BREAST_Human0.94130527
111ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94077296
112SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.91597447
113MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.91562992
114NANOG_16153702_ChIP-ChIP_HESCs_Human0.91526772
115* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.90204853
116* MYC_18940864_ChIP-ChIP_HL60_Human0.90187622
117SOX9_26525672_Chip-Seq_HEART_Mouse0.88731902
118POU5F1_16518401_ChIP-PET_MESCs_Mouse0.88316886
119TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.87998457
120OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.87878413
121ZFP57_27257070_Chip-Seq_ESCs_Mouse0.87696967
122SMAD3_21741376_ChIP-Seq_EPCs_Human0.87282076
123NANOG_16518401_ChIP-PET_MESCs_Mouse0.86766451
124UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.86378239
125WT1_19549856_ChIP-ChIP_CCG9911_Human0.86364556
126* TCF3_18692474_ChIP-Seq_MEFs_Mouse0.86212270
127CTBP1_25329375_ChIP-Seq_LNCAP_Human0.85759044
128FOXM1_26456572_ChIP-Seq_MCF-7_Human0.85747059
129* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.85553565
130PCGF2_27294783_Chip-Seq_NPCs_Mouse0.84448258
131SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84190914
132IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.83661140
133CBP_20019798_ChIP-Seq_JUKART_Human0.83661140
134GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.83322705
135SUZ12_27294783_Chip-Seq_NPCs_Mouse0.83274544
136NFE2_27457419_Chip-Seq_LIVER_Mouse0.82126328

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.77987103
2MP0003111_abnormal_nucleus_morphology3.69568103
3MP0008057_abnormal_DNA_replication3.53494546
4MP0003693_abnormal_embryo_hatching3.49646780
5MP0008877_abnormal_DNA_methylation3.47404280
6MP0008058_abnormal_DNA_repair3.31831962
7MP0001188_hyperpigmentation3.05712476
8MP0003123_paternal_imprinting2.94611040
9MP0003077_abnormal_cell_cycle2.93119640
10MP0004957_abnormal_blastocyst_morpholog2.89866191
11MP0006292_abnormal_olfactory_placode2.83308081
12MP0003880_abnormal_central_pattern2.77513210
13MP0009697_abnormal_copulation2.41722762
14MP0003787_abnormal_imprinting2.36129947
15MP0003786_premature_aging2.20048592
16MP0005171_absent_coat_pigmentation2.18782849
17MP0008007_abnormal_cellular_replicative2.12312504
18MP0003121_genomic_imprinting2.09542755
19MP0008932_abnormal_embryonic_tissue2.04072245
20MP0004859_abnormal_synaptic_plasticity2.00986888
21MP0003136_yellow_coat_color1.98921711
22MP0002938_white_spotting1.83708132
23MP0001730_embryonic_growth_arrest1.73275578
24MP0003890_abnormal_embryonic-extraembry1.71858308
25MP0000350_abnormal_cell_proliferation1.69509592
26MP0006072_abnormal_retinal_apoptosis1.68047178
27MP0003718_maternal_effect1.65681240
28MP0010352_gastrointestinal_tract_polyps1.63299655
29MP0004133_heterotaxia1.62750566
30MP0002210_abnormal_sex_determination1.61782016
31MP0002160_abnormal_reproductive_system1.60182931
32MP0002102_abnormal_ear_morphology1.59552714
33MP0003635_abnormal_synaptic_transmissio1.59379648
34MP0003567_abnormal_fetal_cardiomyocyte1.53117580
35MP0003119_abnormal_digestive_system1.48801764
36MP0000372_irregular_coat_pigmentation1.46269503
37MP0009745_abnormal_behavioral_response1.46088599
38MP0010307_abnormal_tumor_latency1.41068228
39MP0000647_abnormal_sebaceous_gland1.37538303
40MP0001286_abnormal_eye_development1.36048488
41MP0001929_abnormal_gametogenesis1.34335576
42MP0002653_abnormal_ependyma_morphology1.33592398
43MP0002085_abnormal_embryonic_tissue1.33287793
44MP0000427_abnormal_hair_cycle1.32695918
45MP0002735_abnormal_chemical_nociception1.31699649
46MP0006054_spinal_hemorrhage1.31209252
47MP0001672_abnormal_embryogenesis/_devel1.30187772
48MP0005380_embryogenesis_phenotype1.30187772
49MP0002233_abnormal_nose_morphology1.28923002
50MP0000383_abnormal_hair_follicle1.26956547
51MP0001145_abnormal_male_reproductive1.26391071
52MP0002063_abnormal_learning/memory/cond1.26138084
53MP0010030_abnormal_orbit_morphology1.23561084
54MP0002084_abnormal_developmental_patter1.23127320
55MP0002697_abnormal_eye_size1.22899039
56MP0000653_abnormal_sex_gland1.20376462
57MP0005389_reproductive_system_phenotype1.20310627
58MP0002064_seizures1.18942221
59MP0002572_abnormal_emotion/affect_behav1.18820677
60MP0001697_abnormal_embryo_size1.17618556
61MP0010678_abnormal_skin_adnexa1.16151716
62MP0002111_abnormal_tail_morphology1.15201878
63MP0003195_calcinosis1.14763964
64MP0003937_abnormal_limbs/digits/tail_de1.14634037
65MP0005646_abnormal_pituitary_gland1.14311620
66MP0008995_early_reproductive_senescence1.14021761
67MP0003941_abnormal_skin_development1.13367620
68MP0002396_abnormal_hematopoietic_system1.08141177
69MP0002009_preneoplasia1.07615579
70MP0009672_abnormal_birth_weight1.07105713
71MP0001529_abnormal_vocalization1.07081387
72MP0002080_prenatal_lethality1.05284885
73MP0005084_abnormal_gallbladder_morpholo1.05257498
74MP0000678_abnormal_parathyroid_gland1.05170487
75MP0006035_abnormal_mitochondrial_morpho1.05138972
76MP0000358_abnormal_cell_content/1.03734403
77MP0004197_abnormal_fetal_growth/weight/1.03656476
78MP0002086_abnormal_extraembryonic_tissu1.03522285
79MP0005187_abnormal_penis_morphology1.03017171
80MP0003943_abnormal_hepatobiliary_system1.02857907
81MP0003698_abnormal_male_reproductive1.02042315
82MP0001968_abnormal_touch/_nociception1.00790379
83MP0003861_abnormal_nervous_system1.00636331
84MP0002272_abnormal_nervous_system0.99710595
85MP0002751_abnormal_autonomic_nervous0.99199073
86MP0003984_embryonic_growth_retardation0.99058294
87MP0000516_abnormal_urinary_system0.98726206
88MP0005367_renal/urinary_system_phenotyp0.98726206
89MP0002088_abnormal_embryonic_growth/wei0.94897902
90MP0002736_abnormal_nociception_after0.94893972
91MP0000778_abnormal_nervous_system0.94716130
92MP0003935_abnormal_craniofacial_develop0.92684042
93MP0001177_atelectasis0.92551772
94MP0001919_abnormal_reproductive_system0.91722060
95MP0004270_analgesia0.91587424
96MP0009046_muscle_twitch0.91180532
97MP0001119_abnormal_female_reproductive0.90978185
98MP0003806_abnormal_nucleotide_metabolis0.90436604
99MP0005253_abnormal_eye_physiology0.90026635
100MP0004043_abnormal_pH_regulation0.89177092
101MP0003122_maternal_imprinting0.88098922
102MP0005395_other_phenotype0.87463169
103MP0005408_hypopigmentation0.86430226
104MP0001293_anophthalmia0.86011288
105MP0001299_abnormal_eye_distance/0.85190277
106MP0002234_abnormal_pharynx_morphology0.84917231
107MP0005645_abnormal_hypothalamus_physiol0.84250467
108MP0003950_abnormal_plasma_membrane0.83730085
109MP0004215_abnormal_myocardial_fiber0.83579082
110MP0005391_vision/eye_phenotype0.83463375
111MP0003315_abnormal_perineum_morphology0.82533160
112MP0001440_abnormal_grooming_behavior0.82091454
113MP0000569_abnormal_digit_pigmentation0.81208681
114MP0003938_abnormal_ear_development0.80079923
115MP0005248_abnormal_Harderian_gland0.79887127
116MP0002734_abnormal_mechanical_nocicepti0.79060252
117MP0003755_abnormal_palate_morphology0.78153323
118MP0009703_decreased_birth_body0.77871995
119MP0000432_abnormal_head_morphology0.77406261
120MP0000015_abnormal_ear_pigmentation0.76896378
121MP0000313_abnormal_cell_death0.76589519
122MP0002152_abnormal_brain_morphology0.76212278
123MP0002092_abnormal_eye_morphology0.75770256
124MP0000537_abnormal_urethra_morphology0.74616647
125MP0000428_abnormal_craniofacial_morphol0.74514970
126MP0003699_abnormal_female_reproductive0.74447758
127MP0004264_abnormal_extraembryonic_tissu0.74439297
128MP0003936_abnormal_reproductive_system0.73430349
129MP0004134_abnormal_chest_morphology0.72915039
130MP0006036_abnormal_mitochondrial_physio0.72798929
131MP0002067_abnormal_sensory_capabilities0.72546021
132MP0003283_abnormal_digestive_organ0.72274796
133MP0000049_abnormal_middle_ear0.71988338
134MP0002161_abnormal_fertility/fecundity0.71066357
135MP0002254_reproductive_system_inflammat0.70712935
136MP0009379_abnormal_foot_pigmentation0.70582061
137MP0000631_abnormal_neuroendocrine_gland0.70542367
138MP0000579_abnormal_nail_morphology0.70495725
139MP0008789_abnormal_olfactory_epithelium0.69554154
140MP0008260_abnormal_autophagy0.69466427
141MP0001485_abnormal_pinna_reflex0.67206698
142MP0005384_cellular_phenotype0.66641358
143MP0003385_abnormal_body_wall0.64724031
144MP0005394_taste/olfaction_phenotype0.63325551
145MP0005499_abnormal_olfactory_system0.63325551
146MP0002184_abnormal_innervation0.62534073
147MP0005621_abnormal_cell_physiology0.62297721

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.60617663
2Abnormality of the labia minora (HP:0012880)4.42616830
3Astrocytoma (HP:0009592)4.08775184
4Abnormality of the astrocytes (HP:0100707)4.08775184
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.84074533
6Breast hypoplasia (HP:0003187)3.75344321
7Chromsome breakage (HP:0040012)3.73036955
8Glioma (HP:0009733)3.70307479
9Colon cancer (HP:0003003)3.64876443
10Medulloblastoma (HP:0002885)3.52279463
11Ependymoma (HP:0002888)3.45937959
12Agnosia (HP:0010524)3.06360181
13Neoplasm of the oral cavity (HP:0100649)2.96664661
14Supernumerary spleens (HP:0009799)2.91431972
15Absent radius (HP:0003974)2.68972542
16Patellar aplasia (HP:0006443)2.65357534
17Breast aplasia (HP:0100783)2.64895223
18Meckel diverticulum (HP:0002245)2.64098830
19Neoplasm of the adrenal cortex (HP:0100641)2.63887201
20Focal motor seizures (HP:0011153)2.63681165
21Abnormality of chromosome stability (HP:0003220)2.60694137
22Rhabdomyosarcoma (HP:0002859)2.55874082
23Impulsivity (HP:0100710)2.55747392
24Occipital encephalocele (HP:0002085)2.55425321
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.55353619
26Carpal bone hypoplasia (HP:0001498)2.54004710
27Aplasia involving forearm bones (HP:0009822)2.50483344
28Absent forearm bone (HP:0003953)2.50483344
29Abnormality of the ileum (HP:0001549)2.49232137
30Aplasia/Hypoplasia of the breasts (HP:0010311)2.46152958
31Papillary thyroid carcinoma (HP:0002895)2.45322314
32Aplasia/Hypoplasia of the patella (HP:0006498)2.43636411
33Abnormality of the preputium (HP:0100587)2.43501544
34Abnormality of the renal collecting system (HP:0004742)2.42851028
35Intestinal atresia (HP:0011100)2.41213888
36Absent speech (HP:0001344)2.41026468
37Cortical dysplasia (HP:0002539)2.40011996
38Ectopic kidney (HP:0000086)2.39451408
39Horseshoe kidney (HP:0000085)2.38125328
40Bifid tongue (HP:0010297)2.35482921
41Abnormality of midbrain morphology (HP:0002418)2.34877073
42Molar tooth sign on MRI (HP:0002419)2.34877073
43Cerebral hypomyelination (HP:0006808)2.32764607
44Duplicated collecting system (HP:0000081)2.30774036
45Clubbing of toes (HP:0100760)2.25980455
46Pancreatic cysts (HP:0001737)2.25658524
47Small intestinal stenosis (HP:0012848)2.25199071
48Duodenal stenosis (HP:0100867)2.25199071
49Abnormality of DNA repair (HP:0003254)2.24229380
50Abnormality of the lower motor neuron (HP:0002366)2.16184484
51Chronic hepatic failure (HP:0100626)2.14711106
52Triphalangeal thumb (HP:0001199)2.12894746
53Optic nerve hypoplasia (HP:0000609)2.11016433
54Gastrointestinal atresia (HP:0002589)2.08261110
55Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.08010407
56Abnormality of the carotid arteries (HP:0005344)2.05940692
57Biliary tract neoplasm (HP:0100574)2.05165970
58Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.04146153
59True hermaphroditism (HP:0010459)2.03751564
60Median cleft lip (HP:0000161)2.03496312
61Selective tooth agenesis (HP:0001592)2.02697884
62Sloping forehead (HP:0000340)2.01722887
63Nephroblastoma (Wilms tumor) (HP:0002667)2.01195631
64Oligodactyly (hands) (HP:0001180)1.99950076
65Rough bone trabeculation (HP:0100670)1.99417796
66Irregular epiphyses (HP:0010582)1.99104769
67Aplasia/Hypoplasia of the tibia (HP:0005772)1.96463661
68Esophageal atresia (HP:0002032)1.95889784
69Increased nuchal translucency (HP:0010880)1.95327021
70Neoplasm of the adrenal gland (HP:0100631)1.95008996
71Absent thumb (HP:0009777)1.94152280
72Ovarian neoplasm (HP:0100615)1.93711546
73Atonic seizures (HP:0010819)1.93067656
74Abnormality of methionine metabolism (HP:0010901)1.92512380
75Stomach cancer (HP:0012126)1.92428452
76Pancreatic islet-cell hyperplasia (HP:0004510)1.91558573
77Nephronophthisis (HP:0000090)1.90394346
78Embryonal renal neoplasm (HP:0011794)1.90277129
79Myelodysplasia (HP:0002863)1.90099205
80Short tibia (HP:0005736)1.89702996
81Neoplasm of striated muscle (HP:0009728)1.89437254
82Aplasia/Hypoplasia of the sternum (HP:0006714)1.89065266
83Microvesicular hepatic steatosis (HP:0001414)1.88717463
84Abnormality of the duodenum (HP:0002246)1.87445055
85Neoplasm of the small intestine (HP:0100833)1.87043422
86Preaxial hand polydactyly (HP:0001177)1.86419205
87Malignant neoplasm of the central nervous system (HP:0100836)1.85659505
88Nervous tissue neoplasm (HP:0030060)1.85492070
89Neuroectodermal neoplasm (HP:0030061)1.85492070
90Neuroepithelial neoplasm (HP:0030063)1.85492070
91Shawl scrotum (HP:0000049)1.85299644
92Decreased circulating renin level (HP:0003351)1.85286440
93Abnormal lung lobation (HP:0002101)1.85276189
94Hypoplasia of the capital femoral epiphysis (HP:0003090)1.85271593
95Abnormality of alanine metabolism (HP:0010916)1.84882337
96Hyperalaninemia (HP:0003348)1.84882337
97Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.84882337
98Abnormal biliary tract morphology (HP:0012440)1.84846970
99Epileptic encephalopathy (HP:0200134)1.83555724
100Breast carcinoma (HP:0003002)1.83250456
101Freckling (HP:0001480)1.82252946
102Hypogonadotrophic hypogonadism (HP:0000044)1.81348049
103Volvulus (HP:0002580)1.80620733
104Stenosis of the external auditory canal (HP:0000402)1.80449421
105Bile duct proliferation (HP:0001408)1.80156274
106Abnormal biliary tract physiology (HP:0012439)1.80156274
107Small hand (HP:0200055)1.80107288
108Tented upper lip vermilion (HP:0010804)1.79549791
109Pancreatic fibrosis (HP:0100732)1.78492618
110Abnormality of cochlea (HP:0000375)1.75123053
111Atresia of the external auditory canal (HP:0000413)1.74260292
112Abnormal hair whorl (HP:0010721)1.73860186
113Neuroblastoma (HP:0003006)1.73810101
114Primitive neuroectodermal tumor (HP:0030065)1.73810101
115Neuroblastic tumors (HP:0004376)1.73810101
116Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.73810101
117Dandy-Walker malformation (HP:0001305)1.73020058
118Septo-optic dysplasia (HP:0100842)1.72678092
119Abnormality of aspartate family amino acid metabolism (HP:0010899)1.72458783
120Impaired vibration sensation in the lower limbs (HP:0002166)1.72174369
121Abnormality of chromosome segregation (HP:0002916)1.72012077
122Aplasia/hypoplasia of the humerus (HP:0006507)1.71166759
123Cafe-au-lait spot (HP:0000957)1.71060124
124Abnormality of the clitoris (HP:0000056)1.71036409
125Bone marrow hypocellularity (HP:0005528)1.71035513
126Embryonal neoplasm (HP:0002898)1.70676859
127Abnormality of serum amino acid levels (HP:0003112)1.70659373
128Increased hepatocellular lipid droplets (HP:0006565)1.67346368
129Acute encephalopathy (HP:0006846)1.66771272
130Abnormality of the anterior horn cell (HP:0006802)1.65858227
131Degeneration of anterior horn cells (HP:0002398)1.65858227
132Febrile seizures (HP:0002373)1.65641660
133Neoplasm of the colon (HP:0100273)1.65549732
134Astigmatism (HP:0000483)1.65251009
135Rectovaginal fistula (HP:0000143)1.64467529
136Rectal fistula (HP:0100590)1.64467529
137Intestinal fistula (HP:0100819)1.64351650
138Anal atresia (HP:0002023)1.62778243
139Adrenal hypoplasia (HP:0000835)1.62601825
140Hyperactive renin-angiotensin system (HP:0000841)1.62463146
141Postaxial foot polydactyly (HP:0001830)1.61101269
142Progressive inability to walk (HP:0002505)1.60703517
143Spinal muscular atrophy (HP:0007269)1.60697519
144Absent epiphyses (HP:0010577)1.60609354
145Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.60609354
146Oligohydramnios (HP:0001562)1.59780037
147Choanal atresia (HP:0000453)1.59255974
148Medial flaring of the eyebrow (HP:0010747)1.58892017
149Oculomotor apraxia (HP:0000657)1.58673013
150Aplasia/Hypoplasia of the tongue (HP:0010295)1.58411731
151Genital tract atresia (HP:0001827)1.56459597
152Acute necrotizing encephalopathy (HP:0006965)1.56258781
153Abnormal umbilical cord blood vessels (HP:0011403)1.54833727
154Single umbilical artery (HP:0001195)1.54833727
155Abnormality of the fetal cardiovascular system (HP:0010948)1.54833727
156Abnormality of the renal medulla (HP:0100957)1.54633240
157Lipid accumulation in hepatocytes (HP:0006561)1.54578653
158Abnormal auditory evoked potentials (HP:0006958)1.54106453

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRPF4B3.96253598
2AKT33.67881107
3BUB13.47625114
4TSSK62.90986798
5NTRK32.85534941
6CDC72.84985070
7CASK2.84795394
8PNCK2.81697707
9PBK2.81695532
10WEE12.72022040
11TNIK2.67491886
12MST42.55616701
13TRIM282.50414436
14TTK2.46219357
15SRPK12.11767989
16CDK122.08017170
17MKNK22.06525285
18EIF2AK31.91854698
19EIF2AK11.88810603
20PLK31.81250755
21TAF11.79408176
22WNK31.77256953
23LATS11.75605752
24ZAK1.72735441
25BMPR1B1.69289775
26PLK11.60654158
27EPHA21.57721268
28BRAF1.55663726
29PLK41.51541355
30NEK21.49965464
31FRK1.49006835
32CHEK21.44260556
33MKNK11.36386340
34BCR1.35143246
35BRD41.34272827
36MAP3K41.33081042
37ERBB31.29119726
38MAP2K71.28939927
39STK38L1.26916959
40ATR1.20505128
41SGK21.19117351
42NEK11.16598689
43AURKA1.14414934
44CHEK11.08832512
45ERBB41.08310488
46EPHA41.06736615
47MAP3K61.04427238
48BRSK21.04163827
49ACVR1B1.03757169
50BRSK11.02838910
51VRK21.02510393
52PLK21.02398092
53STK161.02062413
54CDK70.93151456
55VRK10.91911258
56CCNB10.90341954
57PASK0.88542262
58KSR10.84460478
59AURKB0.83537680
60SIK30.81689752
61IRAK30.80832305
62STK390.80037525
63CDK80.79633952
64DAPK10.79092891
65CSNK1A1L0.78076184
66PRKCI0.76400149
67FLT30.74330640
68ATM0.74310406
69ALK0.73630917
70RPS6KA40.73263192
71CDK20.71137690
72YES10.70721644
73TLK10.70476243
74SGK30.68350078
75NUAK10.68098931
76NLK0.67624666
77RPS6KB20.67422420
78CSNK1G20.66331091
79SGK4940.65900589
80SGK2230.65900589
81CDK10.65192492
82CSNK1G30.65128580
83MAPK130.63126119
84LATS20.62206224
85MELK0.61290077
86GRK10.60695086
87PINK10.60582694
88MAP4K20.59499198
89FGFR10.59048267
90DYRK30.58856751
91FES0.56612172
92CSNK1E0.54824585
93STK40.54698197
94TYRO30.53030024
95TGFBR10.52861489
96EIF2AK20.51691349
97MET0.51469272
98CDK30.50522798
99PRKCG0.50029456
100CSNK1G10.50013674
101MINK10.48946062
102SCYL20.48530092
103CDK190.48371207
104CDK90.44526282
105FER0.43436231
106OXSR10.43078847
107WNK40.40841632
108MST1R0.40751071
109CLK10.40741392
110CSNK1D0.40640574
111PDK30.40410970
112PDK40.40410970
113RPS6KB10.39401371
114PRKCE0.38851334
115STK100.38609267
116PDK20.38600734
117CDK40.38374833
118CDK60.38247117
119MAP3K120.37920641
120GSK3B0.35633854
121CAMKK20.34483701
122CSNK2A20.34288310
123NME10.33981190
124MAP3K90.33477381
125CSNK2A10.32896070
126NEK90.32472228
127PRKDC0.31614335
128MAP2K40.30073516
129STK30.29324872
130DYRK1A0.28374097
131MAP3K80.27862632
132DYRK20.27109661
133CSNK1A10.27080086
134STK240.23357498

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034303.90034461
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.82525213
3DNA replication_Homo sapiens_hsa030303.52635816
4RNA transport_Homo sapiens_hsa030133.04816563
5Nucleotide excision repair_Homo sapiens_hsa034202.91344841
6RNA polymerase_Homo sapiens_hsa030202.80349542
7Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.77235163
8Spliceosome_Homo sapiens_hsa030402.64612480
9Fanconi anemia pathway_Homo sapiens_hsa034602.63774798
10Homologous recombination_Homo sapiens_hsa034402.60773112
11Cell cycle_Homo sapiens_hsa041102.57794308
12Protein export_Homo sapiens_hsa030602.45134682
13Base excision repair_Homo sapiens_hsa034102.43320350
14Nicotine addiction_Homo sapiens_hsa050332.32920421
15One carbon pool by folate_Homo sapiens_hsa006702.26966608
16Propanoate metabolism_Homo sapiens_hsa006402.24258719
17Proteasome_Homo sapiens_hsa030502.14600547
18RNA degradation_Homo sapiens_hsa030182.07163588
19Basal transcription factors_Homo sapiens_hsa030222.05634409
20mRNA surveillance pathway_Homo sapiens_hsa030151.88170890
21Non-homologous end-joining_Homo sapiens_hsa034501.81275466
22Oocyte meiosis_Homo sapiens_hsa041141.71420481
23Pyrimidine metabolism_Homo sapiens_hsa002401.64679394
24Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.59780732
25Vitamin B6 metabolism_Homo sapiens_hsa007501.56091092
26Fatty acid elongation_Homo sapiens_hsa000621.47047928
27Steroid biosynthesis_Homo sapiens_hsa001001.41257264
28Pyruvate metabolism_Homo sapiens_hsa006201.39844837
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.39475905
30Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.39437218
31Purine metabolism_Homo sapiens_hsa002301.28499246
32Long-term potentiation_Homo sapiens_hsa047201.26318932
33Synaptic vesicle cycle_Homo sapiens_hsa047211.25814567
34Amphetamine addiction_Homo sapiens_hsa050311.22937987
35Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.22913528
36p53 signaling pathway_Homo sapiens_hsa041151.19706179
37Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.15747632
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15073202
39Taste transduction_Homo sapiens_hsa047421.13036967
40Circadian entrainment_Homo sapiens_hsa047131.10138043
41Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.07426048
42Glutamatergic synapse_Homo sapiens_hsa047241.04677869
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.03824392
44Long-term depression_Homo sapiens_hsa047300.97227333
452-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.96393036
46Regulation of autophagy_Homo sapiens_hsa041400.94137398
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.88111170
48Alcoholism_Homo sapiens_hsa050340.87037309
49Epstein-Barr virus infection_Homo sapiens_hsa051690.85367131
50Circadian rhythm_Homo sapiens_hsa047100.83022582
51Collecting duct acid secretion_Homo sapiens_hsa049660.81506800
52Cysteine and methionine metabolism_Homo sapiens_hsa002700.78691339
53Parkinsons disease_Homo sapiens_hsa050120.78012487
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.77861266
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.77413881
56Butanoate metabolism_Homo sapiens_hsa006500.76862654
57Folate biosynthesis_Homo sapiens_hsa007900.75390974
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.74079827
59Systemic lupus erythematosus_Homo sapiens_hsa053220.73380103
60Huntingtons disease_Homo sapiens_hsa050160.73277316
61Selenocompound metabolism_Homo sapiens_hsa004500.71754023
62Thyroid cancer_Homo sapiens_hsa052160.71637435
63Oxidative phosphorylation_Homo sapiens_hsa001900.70398159
64Morphine addiction_Homo sapiens_hsa050320.70193339
65Colorectal cancer_Homo sapiens_hsa052100.69976111
66Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.69799871
67Glutathione metabolism_Homo sapiens_hsa004800.68838662
68Primary bile acid biosynthesis_Homo sapiens_hsa001200.65905581
69Wnt signaling pathway_Homo sapiens_hsa043100.65178164
70Dopaminergic synapse_Homo sapiens_hsa047280.63100776
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62988298
72GABAergic synapse_Homo sapiens_hsa047270.62743247
73Endometrial cancer_Homo sapiens_hsa052130.62156439
74Fatty acid metabolism_Homo sapiens_hsa012120.61812569
75Hippo signaling pathway_Homo sapiens_hsa043900.60858869
76Ribosome_Homo sapiens_hsa030100.60581344
77Lysine degradation_Homo sapiens_hsa003100.59588969
78Carbon metabolism_Homo sapiens_hsa012000.59547614
79Viral carcinogenesis_Homo sapiens_hsa052030.58945489
80Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.56752745
81Basal cell carcinoma_Homo sapiens_hsa052170.56484221
82Metabolic pathways_Homo sapiens_hsa011000.55897585
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.55361794
84Fructose and mannose metabolism_Homo sapiens_hsa000510.55141125
85Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.54927334
86Serotonergic synapse_Homo sapiens_hsa047260.54819093
87Phosphatidylinositol signaling system_Homo sapiens_hsa040700.53492241
88Olfactory transduction_Homo sapiens_hsa047400.53407516
89N-Glycan biosynthesis_Homo sapiens_hsa005100.52585425
90Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.51008421
91HTLV-I infection_Homo sapiens_hsa051660.50012781
92Peroxisome_Homo sapiens_hsa041460.45694995
93Cocaine addiction_Homo sapiens_hsa050300.45351715
94Nitrogen metabolism_Homo sapiens_hsa009100.43054309
95Gap junction_Homo sapiens_hsa045400.42948679
96MicroRNAs in cancer_Homo sapiens_hsa052060.42552529
97Vibrio cholerae infection_Homo sapiens_hsa051100.42467202
98Inositol phosphate metabolism_Homo sapiens_hsa005620.42389959
99TGF-beta signaling pathway_Homo sapiens_hsa043500.41673199
100ErbB signaling pathway_Homo sapiens_hsa040120.40809164
101Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39856959
102Sulfur metabolism_Homo sapiens_hsa009200.39713989
103Fatty acid degradation_Homo sapiens_hsa000710.39237424
104Caffeine metabolism_Homo sapiens_hsa002320.38972081
105Calcium signaling pathway_Homo sapiens_hsa040200.38203126
106Oxytocin signaling pathway_Homo sapiens_hsa049210.38109811
107Insulin secretion_Homo sapiens_hsa049110.38064852
108Hedgehog signaling pathway_Homo sapiens_hsa043400.37573133
109MAPK signaling pathway_Homo sapiens_hsa040100.37551415
110Estrogen signaling pathway_Homo sapiens_hsa049150.37449738
111Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.36650689
112Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.35867714
113Phototransduction_Homo sapiens_hsa047440.35216059
114Dorso-ventral axis formation_Homo sapiens_hsa043200.35080658
115beta-Alanine metabolism_Homo sapiens_hsa004100.34563120
116mTOR signaling pathway_Homo sapiens_hsa041500.34512413
117Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.31489909
118Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.31163668
119Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.30379063
120Retinol metabolism_Homo sapiens_hsa008300.30327124
121Tryptophan metabolism_Homo sapiens_hsa003800.29402591
122Biosynthesis of amino acids_Homo sapiens_hsa012300.28535567
123GnRH signaling pathway_Homo sapiens_hsa049120.27514062
124Ether lipid metabolism_Homo sapiens_hsa005650.27011644
125Axon guidance_Homo sapiens_hsa043600.26596043
126Herpes simplex infection_Homo sapiens_hsa051680.26374045
127Vitamin digestion and absorption_Homo sapiens_hsa049770.25971813
128Tight junction_Homo sapiens_hsa045300.24343071
129FoxO signaling pathway_Homo sapiens_hsa040680.24097904
130Renin secretion_Homo sapiens_hsa049240.23503227
131Steroid hormone biosynthesis_Homo sapiens_hsa001400.22991035
132Melanoma_Homo sapiens_hsa052180.22782543
133Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.22606821
134Alzheimers disease_Homo sapiens_hsa050100.22472995
135Choline metabolism in cancer_Homo sapiens_hsa052310.22254243
136Thyroid hormone signaling pathway_Homo sapiens_hsa049190.22183524
137Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.20781985
138Salivary secretion_Homo sapiens_hsa049700.20754508
139Drug metabolism - other enzymes_Homo sapiens_hsa009830.20522189
140cAMP signaling pathway_Homo sapiens_hsa040240.20193886
141Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.20071372
142Small cell lung cancer_Homo sapiens_hsa052220.19910342
143Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.19569731
144Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.19466186
145Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.18897464
146Adherens junction_Homo sapiens_hsa045200.18575171

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