ZMYM4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)5.03391513
2mitotic sister chromatid cohesion (GO:0007064)4.93179209
3nuclear pore complex assembly (GO:0051292)4.41081164
4nuclear pore organization (GO:0006999)4.38365791
5regulation of RNA export from nucleus (GO:0046831)4.19901373
6cytoplasmic mRNA processing body assembly (GO:0033962)3.92604708
7DNA topological change (GO:0006265)3.60151591
8negative regulation of DNA repair (GO:0045738)3.56578187
9regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.41553900
10negative regulation of histone methylation (GO:0031061)3.41294740
11regulation of nucleobase-containing compound transport (GO:0032239)3.40797450
12glucocorticoid receptor signaling pathway (GO:0042921)3.31976836
13pore complex assembly (GO:0046931)3.28267846
14hippo signaling (GO:0035329)3.21028400
15regulation of DNA endoreduplication (GO:0032875)3.14149791
16regulation of histone H3-K9 methylation (GO:0051570)3.12872978
17DNA unwinding involved in DNA replication (GO:0006268)3.10787590
18paraxial mesoderm development (GO:0048339)3.10274947
19double-strand break repair via nonhomologous end joining (GO:0006303)3.03214537
20non-recombinational repair (GO:0000726)3.03214537
21histone H4-K8 acetylation (GO:0043982)3.00967605
22histone H4-K5 acetylation (GO:0043981)3.00967605
23peptidyl-lysine dimethylation (GO:0018027)3.00826321
24histone H4-K16 acetylation (GO:0043984)2.96176057
25notochord development (GO:0030903)2.91919765
26regulation of sister chromatid cohesion (GO:0007063)2.89937051
27negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.86722768
28negative regulation of translation, ncRNA-mediated (GO:0040033)2.86722768
29regulation of translation, ncRNA-mediated (GO:0045974)2.86722768
30stress granule assembly (GO:0034063)2.84284722
31sister chromatid segregation (GO:0000819)2.82226256
32regulation of centriole replication (GO:0046599)2.80995824
33NLS-bearing protein import into nucleus (GO:0006607)2.79071648
34gene silencing by RNA (GO:0031047)2.79001194
35histone H3-K9 methylation (GO:0051567)2.78111449
36mitotic metaphase plate congression (GO:0007080)2.75532241
37interkinetic nuclear migration (GO:0022027)2.72682161
38positive regulation of mitotic sister chromatid separation (GO:1901970)2.70889705
39positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.70889705
40positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.70889705
41sister chromatid cohesion (GO:0007062)2.69078646
42centriole replication (GO:0007099)2.68878252
43ectodermal placode formation (GO:0060788)2.68706932
44ATP-dependent chromatin remodeling (GO:0043044)2.67228190
45dorsal/ventral axis specification (GO:0009950)2.66686843
46chromatin assembly (GO:0031497)2.64048467
47heterochromatin organization (GO:0070828)2.63890666
48DNA ligation (GO:0006266)2.63562766
49histone H3-K9 demethylation (GO:0033169)2.62148861
50morphogenesis of an epithelial sheet (GO:0002011)2.61348993
51DNA duplex unwinding (GO:0032508)2.59803381
52membrane disassembly (GO:0030397)2.59049377
53nuclear envelope disassembly (GO:0051081)2.59049377
54histone H4-K12 acetylation (GO:0043983)2.58928409
55DNA geometric change (GO:0032392)2.58848011
56metaphase plate congression (GO:0051310)2.58783578
57DNA conformation change (GO:0071103)2.58674114
58body morphogenesis (GO:0010171)2.58595799
59layer formation in cerebral cortex (GO:0021819)2.58399339
60regulation of centrosome cycle (GO:0046605)2.57481203
61corticosteroid receptor signaling pathway (GO:0031958)2.56086718
62regulation of mitotic spindle organization (GO:0060236)2.54930415
63regulation of telomere maintenance (GO:0032204)2.54462650
64protein localization to kinetochore (GO:0034501)2.53044179
65DNA strand elongation involved in DNA replication (GO:0006271)2.52379947
66mRNA stabilization (GO:0048255)2.51791463
67RNA stabilization (GO:0043489)2.51791463
68negative regulation of fibroblast apoptotic process (GO:2000270)2.51677950
69DNA replication initiation (GO:0006270)2.51185156
70regulation of telomere maintenance via telomerase (GO:0032210)2.50846608
71establishment of integrated proviral latency (GO:0075713)2.50176148
72mitotic cytokinesis (GO:0000281)2.47127242
73regulation of translational fidelity (GO:0006450)2.46460782
74mRNA splice site selection (GO:0006376)2.45510008
75histone H3-K4 methylation (GO:0051568)2.45272227
76DNA strand elongation (GO:0022616)2.45250415
77head development (GO:0060322)2.45216289
78centrosome duplication (GO:0051298)2.45087489
79embryonic body morphogenesis (GO:0010172)2.44323626
80embryonic foregut morphogenesis (GO:0048617)2.44280036
81negative regulation of histone modification (GO:0031057)2.44261278
82embryonic retina morphogenesis in camera-type eye (GO:0060059)2.44104544
83histone H2A monoubiquitination (GO:0035518)2.43943907
84spindle checkpoint (GO:0031577)2.43010827
85V(D)J recombination (GO:0033151)2.42551465
86regulation of mitotic sister chromatid separation (GO:0010965)2.42342559
87regulation of mitotic sister chromatid segregation (GO:0033047)2.42342559
88regulation of sister chromatid segregation (GO:0033045)2.42342559
89CENP-A containing nucleosome assembly (GO:0034080)2.40399809
90chromatin remodeling at centromere (GO:0031055)2.40387895
91gene silencing (GO:0016458)2.40242200
92mitotic chromosome condensation (GO:0007076)2.39607603
93histone H3-K36 demethylation (GO:0070544)2.39262110
94DNA replication-independent nucleosome organization (GO:0034724)2.39146275
95DNA replication-independent nucleosome assembly (GO:0006336)2.39146275
96regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.38610641
97regulation of mitotic metaphase/anaphase transition (GO:0030071)2.38610641
98histone lysine methylation (GO:0034968)2.38042429
99nucleus localization (GO:0051647)2.37943991
100establishment of nucleus localization (GO:0040023)2.37930100
101spliceosomal tri-snRNP complex assembly (GO:0000244)2.36805073
102chromosome condensation (GO:0030261)2.35834877
103regulation of posttranscriptional gene silencing (GO:0060147)2.35171366
104regulation of gene silencing by miRNA (GO:0060964)2.35171366
105regulation of gene silencing by RNA (GO:0060966)2.35171366
106monoubiquitinated protein deubiquitination (GO:0035520)2.34875031
107histone H3-K4 trimethylation (GO:0080182)2.34322392
108protein-DNA complex disassembly (GO:0032986)2.34232371
109nucleosome disassembly (GO:0006337)2.34232371
110gastrulation with mouth forming second (GO:0001702)2.34104908
111negative regulation of chromosome segregation (GO:0051985)2.33745419
112negative regulation of DNA-dependent DNA replication (GO:2000104)2.33627025
113regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.33136151
114mitotic spindle checkpoint (GO:0071174)2.33007683
115positive regulation of chromosome segregation (GO:0051984)2.32993446
116histone lysine demethylation (GO:0070076)2.32878328
117negative regulation of chromatin modification (GO:1903309)2.32693412
118negative regulation of mitotic sister chromatid separation (GO:2000816)2.31868636
119negative regulation of sister chromatid segregation (GO:0033046)2.31868636
120negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.31868636
121negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.31868636
122negative regulation of mitotic sister chromatid segregation (GO:0033048)2.31868636
123anterior/posterior axis specification, embryo (GO:0008595)2.31350079
124regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.28942124
125protein localization to chromosome (GO:0034502)2.28136726
126mitotic spindle organization (GO:0007052)2.27773150
127positive regulation of SMAD protein import into nucleus (GO:0060391)2.27621988
128regulation of DNA damage checkpoint (GO:2000001)2.27445410
129negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.27125592
130planar cell polarity pathway involved in neural tube closure (GO:0090179)2.26292603
131DNA packaging (GO:0006323)2.26178267
132positive regulation of dendritic spine morphogenesis (GO:0061003)2.26100409
133DNA replication-dependent nucleosome assembly (GO:0006335)2.25776966
134DNA replication-dependent nucleosome organization (GO:0034723)2.25776966
135DNA double-strand break processing (GO:0000729)2.25597855
136axon extension involved in axon guidance (GO:0048846)2.25236211
137neuron projection extension involved in neuron projection guidance (GO:1902284)2.25236211
138histone exchange (GO:0043486)2.24988729
139mitotic spindle assembly checkpoint (GO:0007094)2.24983333
140histone methylation (GO:0016571)2.24530318
141mitotic sister chromatid segregation (GO:0000070)2.24086176
142positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.24033986
143regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.24033986
144regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.23904091
145establishment of chromosome localization (GO:0051303)2.23479929
146histone H3-K9 modification (GO:0061647)2.22515890
147apical protein localization (GO:0045176)2.22187735
148histone H4 acetylation (GO:0043967)2.22091986
149mitotic nuclear envelope disassembly (GO:0007077)2.19221978
150regulation of centrosome duplication (GO:0010824)2.18482098
151histone demethylation (GO:0016577)2.18462092
152peptidyl-lysine trimethylation (GO:0018023)2.18279344
153protein localization to chromosome, centromeric region (GO:0071459)2.17818239
154regulation of chromosome segregation (GO:0051983)2.16781193

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.39417710
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.05234757
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.77084214
4RBPJ_22232070_ChIP-Seq_NCS_Mouse3.40300361
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.31273792
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.14485274
7EGR1_19374776_ChIP-ChIP_THP-1_Human2.99953208
8ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.82320420
9E2F4_17652178_ChIP-ChIP_JURKAT_Human2.71361661
10TP63_19390658_ChIP-ChIP_HaCaT_Human2.57672714
11GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.48353120
12EZH2_22144423_ChIP-Seq_EOC_Human2.43366516
13HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.41787895
14SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.15906337
15TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.11698230
16ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.85998666
17DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.84813970
18SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.82607241
19BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.81445121
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.79116559
21* PKCTHETA_26484144_Chip-Seq_BREAST_Human1.75534663
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.71294242
23FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.69966488
24FUS_26573619_Chip-Seq_HEK293_Human1.67861492
25MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.65261795
26ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.59608888
27ZFP281_27345836_Chip-Seq_ESCs_Mouse1.57818800
28SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.55964860
29TAF15_26573619_Chip-Seq_HEK293_Human1.54252220
30WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.52541729
31E2F1_21310950_ChIP-Seq_MCF-7_Human1.52060820
32STAT6_21828071_ChIP-Seq_BEAS2B_Human1.50872644
33NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.50437158
34ZFP281_18757296_ChIP-ChIP_E14_Mouse1.42392857
35PIAS1_25552417_ChIP-Seq_VCAP_Human1.41910612
36MYC_18555785_ChIP-Seq_MESCs_Mouse1.41518485
37POU5F1_16153702_ChIP-ChIP_HESCs_Human1.37091814
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.35907460
39SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.35493294
40CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.35162098
41* ISL1_27105846_Chip-Seq_CPCs_Mouse1.34597433
42MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.34570142
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32733017
44FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.32631671
45EWS_26573619_Chip-Seq_HEK293_Human1.32528240
46EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.31728176
47TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.31612547
48TBX3_20139965_ChIP-Seq_ESCs_Mouse1.30147879
49EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.29181565
50OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29083274
51TBX3_20139965_ChIP-Seq_MESCs_Mouse1.29050649
52P300_19829295_ChIP-Seq_ESCs_Human1.27564414
53YAP1_20516196_ChIP-Seq_MESCs_Mouse1.27472907
54YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.27298690
55SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.25851059
56KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.24672034
57KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.24672034
58KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.24672034
59ELK1_19687146_ChIP-ChIP_HELA_Human1.24642202
60POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.24434801
61MYCN_18555785_ChIP-Seq_MESCs_Mouse1.23910640
62SOX2_16153702_ChIP-ChIP_HESCs_Human1.22803365
63ZNF274_21170338_ChIP-Seq_K562_Hela1.22188252
64ESR1_15608294_ChIP-ChIP_MCF-7_Human1.21705232
65SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20232236
66NANOG_21062744_ChIP-ChIP_HESCs_Human1.18840962
67GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18722709
68SOX2_18555785_ChIP-Seq_MESCs_Mouse1.17789181
69TP53_16413492_ChIP-PET_HCT116_Human1.16409307
70GBX2_23144817_ChIP-Seq_PC3_Human1.15222715
71* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13838370
72TCF3_18692474_ChIP-Seq_MESCs_Mouse1.12574447
73NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.12390069
74SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.12052903
75WT1_19549856_ChIP-ChIP_CCG9911_Human1.11569847
76PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11469158
77SALL4_18804426_ChIP-ChIP_XEN_Mouse1.11166273
78RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.10818942
79* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10288196
80STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.10245660
81CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.09569450
82EP300_21415370_ChIP-Seq_HL-1_Mouse1.09396568
83IGF1R_20145208_ChIP-Seq_DFB_Human1.07901902
84TCF4_18268006_ChIP-ChIP_LS174T_Human1.07846859
85RING1B_27294783_Chip-Seq_NPCs_Mouse1.07299038
86STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.07045277
87STAT3_23295773_ChIP-Seq_U87_Human1.06912360
88SMAD3_21741376_ChIP-Seq_EPCs_Human1.06862388
89NANOG_16153702_ChIP-ChIP_HESCs_Human1.05520254
90PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.04432648
91FOXM1_26456572_ChIP-Seq_MCF-7_Human1.04170064
92AR_21572438_ChIP-Seq_LNCaP_Human1.03623888
93CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03405866
94TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03050073
95AR_19668381_ChIP-Seq_PC3_Human1.02504512
96TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.02314455
97TOP2B_26459242_ChIP-Seq_MCF-7_Human1.02086599
98GATA1_26923725_Chip-Seq_HPCs_Mouse1.01365373
99NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.01060708
100BRD4_25478319_ChIP-Seq_HGPS_Human1.00958707
101SOX9_26525672_Chip-Seq_HEART_Mouse0.99344155
102CIITA_25753668_ChIP-Seq_RAJI_Human0.98911418
103RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.97789061
104AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97764552
105ARNT_22903824_ChIP-Seq_MCF-7_Human0.97475388
106MYC_22102868_ChIP-Seq_BL_Human0.95189006
107CBX2_27304074_Chip-Seq_ESCs_Mouse0.95172681
108ZFX_18555785_ChIP-Seq_MESCs_Mouse0.95124148
109* TCF4_23295773_ChIP-Seq_U87_Human0.94970860
110CDX2_19796622_ChIP-Seq_MESCs_Mouse0.94943363
111CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94712394
112SMAD4_21799915_ChIP-Seq_A2780_Human0.94638063
113* CTNNB1_20460455_ChIP-Seq_HCT116_Human0.94046269
114KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.93867083
115SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.93419401
116MYC_19079543_ChIP-ChIP_MESCs_Mouse0.93167361
117POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.92642653
118TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92642653
119AR_21909140_ChIP-Seq_LNCAP_Human0.92108088
120MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91846467
121NANOG_18555785_Chip-Seq_ESCs_Mouse0.91493617
122* CHD1_26751641_Chip-Seq_LNCaP_Human0.90834797
123POU3F2_20337985_ChIP-ChIP_501MEL_Human0.90784141
124POU5F1_16518401_ChIP-PET_MESCs_Mouse0.90184844
125NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.89804309
126WT1_25993318_ChIP-Seq_PODOCYTE_Human0.89040875
127PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.88984857
128SOX17_20123909_ChIP-Seq_XEN_Mouse0.88724359
129CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.87958872
130KDM2B_26808549_Chip-Seq_JURKAT_Human0.87702707
131NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.87573081
132NRF2_20460467_ChIP-Seq_MEFs_Mouse0.87573081
133RNF2_27304074_Chip-Seq_NSC_Mouse0.87175128
134RARB_27405468_Chip-Seq_BRAIN_Mouse0.86833605
135ZNF217_24962896_ChIP-Seq_MCF-7_Human0.86825501
136MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.86600550
137SOX2_21211035_ChIP-Seq_LN229_Gbm0.86395914
138PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.84828611
139AHR_22903824_ChIP-Seq_MCF-7_Human0.83501846
140CTBP2_25329375_ChIP-Seq_LNCAP_Human0.82988457

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003123_paternal_imprinting3.03961215
2MP0003121_genomic_imprinting2.93485004
3MP0003122_maternal_imprinting2.79043085
4MP0000569_abnormal_digit_pigmentation2.62781835
5MP0000537_abnormal_urethra_morphology2.25760114
6MP0003890_abnormal_embryonic-extraembry2.25745096
7MP0008877_abnormal_DNA_methylation2.25113956
8MP0003787_abnormal_imprinting2.24353915
9MP0010030_abnormal_orbit_morphology2.02242365
10MP0008057_abnormal_DNA_replication2.00140955
11MP0010094_abnormal_chromosome_stability1.97456064
12MP0006292_abnormal_olfactory_placode1.90816517
13MP0005076_abnormal_cell_differentiation1.77216374
14MP0003111_abnormal_nucleus_morphology1.77139077
15MP0001293_anophthalmia1.74408642
16MP0005248_abnormal_Harderian_gland1.73660532
17MP0002084_abnormal_developmental_patter1.69748368
18MP0009697_abnormal_copulation1.69525012
19MP0003937_abnormal_limbs/digits/tail_de1.60835359
20MP0005367_renal/urinary_system_phenotyp1.60211072
21MP0000516_abnormal_urinary_system1.60211072
22MP0000428_abnormal_craniofacial_morphol1.58404998
23MP0003385_abnormal_body_wall1.54555429
24MP0003935_abnormal_craniofacial_develop1.54138719
25MP0010352_gastrointestinal_tract_polyps1.53105275
26MP0005623_abnormal_meninges_morphology1.52945740
27MP0002653_abnormal_ependyma_morphology1.52482317
28MP0003119_abnormal_digestive_system1.50329211
29MP0004233_abnormal_muscle_weight1.48551514
30MP0003077_abnormal_cell_cycle1.48402002
31MP0003693_abnormal_embryo_hatching1.46754662
32MP0004859_abnormal_synaptic_plasticity1.46540057
33MP0004272_abnormal_basement_membrane1.45828867
34MP0004197_abnormal_fetal_growth/weight/1.45685044
35MP0002085_abnormal_embryonic_tissue1.44828023
36MP0003861_abnormal_nervous_system1.44427015
37MP0000778_abnormal_nervous_system1.43101259
38MP0009703_decreased_birth_body1.38090113
39MP0006072_abnormal_retinal_apoptosis1.36844639
40MP0005187_abnormal_penis_morphology1.36715546
41MP0010307_abnormal_tumor_latency1.32674585
42MP0003755_abnormal_palate_morphology1.31855534
43MP0002938_white_spotting1.30354914
44MP0000566_synostosis1.28876399
45MP0001672_abnormal_embryogenesis/_devel1.28658609
46MP0005380_embryogenesis_phenotype1.28658609
47MP0003315_abnormal_perineum_morphology1.26943204
48MP0002877_abnormal_melanocyte_morpholog1.26387465
49MP0003942_abnormal_urinary_system1.25589396
50MP0001730_embryonic_growth_arrest1.25158506
51MP0000534_abnormal_ureter_morphology1.20184786
52MP0008007_abnormal_cellular_replicative1.19849453
53MP0003283_abnormal_digestive_organ1.19641178
54MP0001697_abnormal_embryo_size1.19410407
55MP0009053_abnormal_anal_canal1.18449786
56MP0000350_abnormal_cell_proliferation1.18014510
57MP0003984_embryonic_growth_retardation1.17304698
58MP0002932_abnormal_joint_morphology1.17261306
59MP0002088_abnormal_embryonic_growth/wei1.17176087
60MP0000432_abnormal_head_morphology1.17032268
61MP0002116_abnormal_craniofacial_bone1.16694900
62MP0000631_abnormal_neuroendocrine_gland1.16558042
63MP0002233_abnormal_nose_morphology1.14959271
64MP0003567_abnormal_fetal_cardiomyocyte1.14715900
65MP0000049_abnormal_middle_ear1.13692851
66MP0002697_abnormal_eye_size1.13635764
67MP0000733_abnormal_muscle_development1.12713367
68MP0002086_abnormal_extraembryonic_tissu1.12149956
69MP0003115_abnormal_respiratory_system1.11010246
70MP0002092_abnormal_eye_morphology1.10642376
71MP0008438_abnormal_cutaneous_collagen1.10196936
72MP0002249_abnormal_larynx_morphology1.08826481
73MP0008058_abnormal_DNA_repair1.08765608
74MP0009672_abnormal_birth_weight1.07005422
75MP0004134_abnormal_chest_morphology1.05917928
76MP0001177_atelectasis1.04810084
77MP0009780_abnormal_chondrocyte_physiolo1.03817238
78MP0004957_abnormal_blastocyst_morpholog1.03404548
79MP0000462_abnormal_digestive_system1.03041113
80MP0008932_abnormal_embryonic_tissue1.02887014
81MP0002152_abnormal_brain_morphology1.01947575
82MP0003705_abnormal_hypodermis_morpholog1.01200462
83MP0002114_abnormal_axial_skeleton1.00915442
84MP0001286_abnormal_eye_development1.00778693
85MP0001299_abnormal_eye_distance/1.00532847
86MP0009250_abnormal_appendicular_skeleto0.98374603
87MP0002111_abnormal_tail_morphology0.97367957
88MP0005503_abnormal_tendon_morphology0.97101053
89MP0010368_abnormal_lymphatic_system0.96770525
90MP0002102_abnormal_ear_morphology0.96277888
91MP0002081_perinatal_lethality0.96236581
92MP0001188_hyperpigmentation0.95295637
93MP0005499_abnormal_olfactory_system0.94155203
94MP0005394_taste/olfaction_phenotype0.94155203
95MP0005391_vision/eye_phenotype0.93838126
96MP0003943_abnormal_hepatobiliary_system0.93047824
97MP0002210_abnormal_sex_determination0.91596211
98MP0002009_preneoplasia0.90751071
99MP0001915_intracranial_hemorrhage0.90257589
100MP0002177_abnormal_outer_ear0.89324439
101MP0002925_abnormal_cardiovascular_devel0.88625982
102MP0004885_abnormal_endolymph0.87531363
103MP0002080_prenatal_lethality0.86517231
104MP0008789_abnormal_olfactory_epithelium0.85935931
105MP0003941_abnormal_skin_development0.83746481
106MP0004811_abnormal_neuron_physiology0.83590740
107MP0000762_abnormal_tongue_morphology0.82579958
108MP0002109_abnormal_limb_morphology0.82441240
109MP0002234_abnormal_pharynx_morphology0.82285252
110MP0001145_abnormal_male_reproductive0.82078739
111MP0002108_abnormal_muscle_morphology0.81921002
112MP0002184_abnormal_innervation0.81817816
113MP0001661_extended_life_span0.80864735
114MP0003938_abnormal_ear_development0.80424619
115MP0003221_abnormal_cardiomyocyte_apopto0.80423013
116MP0004808_abnormal_hematopoietic_stem0.80032041
117MP0002751_abnormal_autonomic_nervous0.79998729
118MP0010630_abnormal_cardiac_muscle0.79934395
119MP0000955_abnormal_spinal_cord0.78679582
120MP0003635_abnormal_synaptic_transmissio0.78586293
121MP0005171_absent_coat_pigmentation0.77934245

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.74252310
2Short 4th metacarpal (HP:0010044)3.57079445
3Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.57079445
4Cortical dysplasia (HP:0002539)3.41498978
5Abnormality of the astrocytes (HP:0100707)2.85476440
6Astrocytoma (HP:0009592)2.85476440
7Neoplasm of the oral cavity (HP:0100649)2.65615008
8Renal duplication (HP:0000075)2.64271846
9Abnormality of the 4th metacarpal (HP:0010012)2.62794507
10Increased nuchal translucency (HP:0010880)2.60480342
11Medulloblastoma (HP:0002885)2.57224646
12Ependymoma (HP:0002888)2.56659922
13Hyperacusis (HP:0010780)2.54034466
14Macroorchidism (HP:0000053)2.52896673
15Abnormal hair whorl (HP:0010721)2.48557024
16Glioma (HP:0009733)2.46063884
17Midline defect of the nose (HP:0004122)2.44367281
18Chromsome breakage (HP:0040012)2.39571072
19Chromosomal breakage induced by crosslinking agents (HP:0003221)2.38610819
20Abnormality of the labia minora (HP:0012880)2.38384526
21Obsessive-compulsive behavior (HP:0000722)2.35782102
22Papillary thyroid carcinoma (HP:0002895)2.30000401
23Renovascular hypertension (HP:0100817)2.25191479
24Trigonocephaly (HP:0000243)2.22800951
25Heterotopia (HP:0002282)2.22565293
26High anterior hairline (HP:0009890)2.20269176
27Embryonal renal neoplasm (HP:0011794)2.16242387
28Cystic hygroma (HP:0000476)2.15940473
29Truncal obesity (HP:0001956)2.15839201
30Termporal pattern (HP:0011008)2.07665483
31Insidious onset (HP:0003587)2.07665483
32Elfin facies (HP:0004428)2.05697655
33Narrow palate (HP:0000189)2.03755191
34Colon cancer (HP:0003003)2.01760480
35Thyroid carcinoma (HP:0002890)2.01331176
36Abnormal number of incisors (HP:0011064)1.98245838
37Supernumerary spleens (HP:0009799)1.98201106
38Shallow orbits (HP:0000586)1.98080886
39Abnormality of the fingertips (HP:0001211)1.97433674
40Abnormality of the ischium (HP:0003174)1.97283722
41Sacral dimple (HP:0000960)1.95983568
42Abnormality of the phalanges of the hallux (HP:0010057)1.95349955
43Supernumerary ribs (HP:0005815)1.94958482
44Gonadotropin excess (HP:0000837)1.94051684
45Acute myeloid leukemia (HP:0004808)1.93972747
46Abnormality of the lower motor neuron (HP:0002366)1.93351832
47Broad thumb (HP:0011304)1.92777394
48Abnormality of the diencephalon (HP:0010662)1.91968837
49Subacute progressive viral hepatitis (HP:0006572)1.91658924
50Selective tooth agenesis (HP:0001592)1.91165386
51Neoplasm of striated muscle (HP:0009728)1.90619365
52Abnormality of the nasal septum (HP:0000419)1.90338923
53Broad palm (HP:0001169)1.87764133
54Hepatoblastoma (HP:0002884)1.86756430
55Flat cornea (HP:0007720)1.86335196
56Overgrowth (HP:0001548)1.86027840
57Abnormality of chromosome stability (HP:0003220)1.83961112
58Smooth philtrum (HP:0000319)1.83094498
59Hypoplasia of the maxilla (HP:0000327)1.82693215
60Overriding aorta (HP:0002623)1.81326759
61Abnormality of chromosome segregation (HP:0002916)1.81280343
62Proximal placement of thumb (HP:0009623)1.80781242
63Deep philtrum (HP:0002002)1.80638282
64Long eyelashes (HP:0000527)1.79170593
65Bifid tongue (HP:0010297)1.78277703
66Missing ribs (HP:0000921)1.77949773
67Hypoplastic labia majora (HP:0000059)1.77511876
68Relative macrocephaly (HP:0004482)1.75511240
69Facial hemangioma (HP:0000329)1.75368544
70Abnormal lung lobation (HP:0002101)1.74375277
71Rhabdomyosarcoma (HP:0002859)1.73475350
72Deviation of the thumb (HP:0009603)1.73435165
73Increased number of teeth (HP:0011069)1.72779480
74Pointed chin (HP:0000307)1.71126557
75Supernumerary bones of the axial skeleton (HP:0009144)1.69743692
76Broad phalanges of the hand (HP:0009768)1.68329893
77Short humerus (HP:0005792)1.68057334
78Omphalocele (HP:0001539)1.67910871
79Cubitus valgus (HP:0002967)1.67069382
80Neoplasm of the heart (HP:0100544)1.65743576
81Vertebral arch anomaly (HP:0008438)1.64883230
82Low anterior hairline (HP:0000294)1.64789777
83Bowel diverticulosis (HP:0005222)1.64591863
84Curly hair (HP:0002212)1.64302565
85Aqueductal stenosis (HP:0002410)1.64212930
86Attention deficit hyperactivity disorder (HP:0007018)1.64106752
87Sandal gap (HP:0001852)1.63524627
88Cutaneous finger syndactyly (HP:0010554)1.63443064
89Short middle phalanx of the 5th finger (HP:0004220)1.63347210
90Absent frontal sinuses (HP:0002688)1.62848452
91Overlapping toe (HP:0001845)1.62649272
92Patellar dislocation (HP:0002999)1.62410726
93Gastrointestinal carcinoma (HP:0002672)1.62021327
94Malignant gastrointestinal tract tumors (HP:0006749)1.62021327
95Absent eyebrow (HP:0002223)1.61729336
96Prominent nose (HP:0000448)1.60622222
97Abnormality of the calcaneus (HP:0008364)1.60217064
98Aplasia/Hypoplasia of the sternum (HP:0006714)1.59477737
99Abnormality of the labia majora (HP:0012881)1.59116444
100Excessive salivation (HP:0003781)1.58834460
101Drooling (HP:0002307)1.58834460
102Broad finger (HP:0001500)1.58754284
103Megalocornea (HP:0000485)1.58054298
104Hypospadias (HP:0000047)1.57809754
105Urethral obstruction (HP:0000796)1.57609800
106Buphthalmos (HP:0000557)1.57486627
107Fibrous tissue neoplasm (HP:0012316)1.57453695
108Abnormality of dentin (HP:0010299)1.57032688
109Transitional cell carcinoma of the bladder (HP:0006740)1.57011489
110Skull defect (HP:0001362)1.56984403
111Genetic anticipation (HP:0003743)1.56294677
112Spastic diplegia (HP:0001264)1.55769166
113Rib fusion (HP:0000902)1.55766159
114Abnormality of the parathyroid morphology (HP:0011766)1.55230667
115Pulmonic stenosis (HP:0001642)1.54394735
116Tented upper lip vermilion (HP:0010804)1.53838943
117Short philtrum (HP:0000322)1.53490907
118Neoplasm of the small intestine (HP:0100833)1.53081506
119Neoplasm of the adrenal cortex (HP:0100641)1.53011787
120Insomnia (HP:0100785)1.52551326
121Synophrys (HP:0000664)1.51533615
122Hypoplastic ischia (HP:0003175)1.51526071
123Large earlobe (HP:0009748)1.50982845
124Vesicoureteral reflux (HP:0000076)1.50761954
125Calcaneovalgus deformity (HP:0001848)1.50677725
126Ectopic kidney (HP:0000086)1.50446328
127Cutaneous syndactyly (HP:0012725)1.50258172
128Ankyloglossia (HP:0010296)1.50117256
129Short phalanx of the thumb (HP:0009660)1.50050659
130Thin upper lip vermilion (HP:0000219)1.49902355
131Abnormality of the distal phalanx of the thumb (HP:0009617)1.49566905
132Broad phalanx (HP:0006009)1.49258762
133Hypoplastic pelvis (HP:0008839)1.49158870
134Shoulder girdle muscle weakness (HP:0003547)1.49151137
135Preaxial foot polydactyly (HP:0001841)1.48713784
136Benign neoplasm of the central nervous system (HP:0100835)1.48458028
137Fibroma (HP:0010614)1.48387101
138Bladder carcinoma (HP:0002862)1.48349573
139Bladder neoplasm (HP:0009725)1.48349573
140Short middle phalanx of finger (HP:0005819)1.48300130
141Facial cleft (HP:0002006)1.48239994
142Nephroblastoma (Wilms tumor) (HP:0002667)1.47916407
143Anal stenosis (HP:0002025)1.47526929
144Abnormality of the antihelix (HP:0009738)1.46856251
145Intestinal atresia (HP:0011100)1.46499122
146Chin dimple (HP:0010751)1.46298227
147Acute lymphatic leukemia (HP:0006721)1.44846377
148Abnormality involving the epiphyses of the upper limbs (HP:0003839)1.44799764
149Aplasia/Hypoplasia of the uvula (HP:0010293)1.44490132
150Ectopic anus (HP:0004397)1.44348414
151Abnormality of the epiphyses of the hand (HP:0005924)1.42960407
152Uterine leiomyosarcoma (HP:0002891)1.42936248
153Leiomyosarcoma (HP:0100243)1.42936248
154Wide nose (HP:0000445)1.42925868
155Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.42632916
156Neonatal short-limb short stature (HP:0008921)1.42259560
157Cafe-au-lait spot (HP:0000957)1.41762379
158Embryonal neoplasm (HP:0002898)1.40454060

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK123.92377499
2CDC73.62927881
3LATS12.76874454
4STK32.47935711
5BRD42.47095027
6MKNK12.16754832
7BMPR1B2.06923063
8MAP3K42.00494303
9PNCK1.97515325
10ICK1.95460893
11PRKD31.75803127
12CAMK1G1.74094351
13STK38L1.73125661
14NTRK31.72771961
15SRPK11.72262324
16CASK1.71029532
17MARK11.69097146
18TNIK1.67976427
19ALK1.67836724
20NEK21.66438793
21PDGFRA1.59808393
22PLK41.57649156
23CAMK1D1.57338058
24MKNK21.56229362
25TTK1.50933959
26BRSK21.49887012
27SCYL21.49781567
28LATS21.42463722
29TAF11.37839203
30PLK31.34491589
31ATR1.33531896
32CDK61.33462154
33EEF2K1.31211337
34MTOR1.31107390
35FGFR11.28543187
36BCR1.26603855
37CHEK21.26435819
38MAP3K101.26094624
39EIF2AK31.26026351
40KSR11.25219811
41MAP3K91.19489222
42ATM1.18912515
43CHEK11.18828969
44TRIM281.13472137
45CDK91.11523162
46PTK61.09366313
47PKN21.07887156
48RIPK11.07251626
49TYRO31.06236805
50NTRK21.00672271
51CDK40.99668019
52EIF2AK10.99102936
53FGFR20.98339031
54WNK10.97688022
55PASK0.97124144
56CDK20.96255675
57DDR20.94380695
58PLK10.88644311
59ERBB30.88017221
60CDK10.87679728
61PBK0.87123715
62CDK70.86843344
63NTRK10.85184506
64PAK60.84956800
65STK240.83008706
66PLK20.81794105
67SGK30.81146474
68PDGFRB0.81132401
69CSNK1A1L0.80412091
70NEK10.80395823
71MAPK100.78543582
72AKT30.78248264
73MAPK140.77556753
74CSNK1D0.76957920
75MET0.76661825
76FLT30.73918181
77PRKDC0.73863454
78GSK3B0.73594882
79MUSK0.72238058
80CDC42BPA0.70496627
81RET0.69357037
82YES10.68977361
83CSNK1E0.68880859
84CLK10.67811615
85MINK10.66986135
86WNK30.66296407
87MELK0.66252748
88TGFBR10.65811304
89OBSCN0.64421156
90CDK80.64417371
91PAK20.62724014
92ERBB40.62646695
93NEK90.62438498
94SGK20.62321763
95UHMK10.62177128
96WEE10.61429309
97DMPK0.61305179
98RPS6KB10.60517122
99MAP2K40.60281021
100RPS6KB20.60064491
101KSR20.58618962
102SIK20.58267451
103NUAK10.57371225
104INSRR0.57138565
105MAPK80.56740443
106MAP2K70.56081327
107SGK2230.55955134
108SGK4940.55955134
109MAPK130.55839878
110FGFR30.55209783
111ACVR1B0.53648799
112DYRK30.53389742
113RPS6KA20.52788742
114MAP3K60.52354394
115CDK30.52222801
116CSNK1G20.51960137
117RPS6KA40.51387565
118BRAF0.50487872
119MARK20.50357726
120SGK10.49440550
121AKT10.48964219
122HIPK20.48375833
123ERBB20.48150130
124BUB10.47937554
125CSNK1G10.47709592
126TSSK60.47555319
127EPHA40.47279965
128AURKB0.46051296
129CDK180.45716354
130BRSK10.44150434

Predicted pathways (KEGG)

RankGene SetZ-score
1mRNA surveillance pathway_Homo sapiens_hsa030151.96751950
2Cell cycle_Homo sapiens_hsa041101.86996055
3Basal cell carcinoma_Homo sapiens_hsa052171.75735147
4Oocyte meiosis_Homo sapiens_hsa041141.66367748
5Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.66306851
6Hippo signaling pathway_Homo sapiens_hsa043901.59737898
7Colorectal cancer_Homo sapiens_hsa052101.55279248
8Hedgehog signaling pathway_Homo sapiens_hsa043401.53416998
9RNA transport_Homo sapiens_hsa030131.48236663
10Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.47316385
11Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.44535210
12Dorso-ventral axis formation_Homo sapiens_hsa043201.43697727
13MicroRNAs in cancer_Homo sapiens_hsa052061.42573515
14Wnt signaling pathway_Homo sapiens_hsa043101.40082491
15Endometrial cancer_Homo sapiens_hsa052131.37642262
16Fanconi anemia pathway_Homo sapiens_hsa034601.35189137
17Long-term potentiation_Homo sapiens_hsa047201.34880899
18mTOR signaling pathway_Homo sapiens_hsa041501.34359144
19Thyroid hormone signaling pathway_Homo sapiens_hsa049191.33994711
20Adherens junction_Homo sapiens_hsa045201.28714755
21Spliceosome_Homo sapiens_hsa030401.25802169
22Glioma_Homo sapiens_hsa052141.24978132
23Chronic myeloid leukemia_Homo sapiens_hsa052201.24062025
24Alcoholism_Homo sapiens_hsa050341.21529078
25ECM-receptor interaction_Homo sapiens_hsa045121.20681498
26Axon guidance_Homo sapiens_hsa043601.18698795
27TGF-beta signaling pathway_Homo sapiens_hsa043501.18339481
28Nicotine addiction_Homo sapiens_hsa050331.16809525
29Mismatch repair_Homo sapiens_hsa034301.15996278
30Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.14603183
31Melanogenesis_Homo sapiens_hsa049161.12390673
32Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.12215677
33Lysine degradation_Homo sapiens_hsa003101.11516888
34Circadian entrainment_Homo sapiens_hsa047131.11404934
35Estrogen signaling pathway_Homo sapiens_hsa049151.09544185
36ErbB signaling pathway_Homo sapiens_hsa040121.09147643
37Dopaminergic synapse_Homo sapiens_hsa047281.09103199
38Gap junction_Homo sapiens_hsa045401.06397572
39Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.05990137
40Non-small cell lung cancer_Homo sapiens_hsa052231.05509528
41Renin secretion_Homo sapiens_hsa049241.04471516
42Amphetamine addiction_Homo sapiens_hsa050311.02808126
43Long-term depression_Homo sapiens_hsa047301.02387707
44Phototransduction_Homo sapiens_hsa047441.02263775
45Proteoglycans in cancer_Homo sapiens_hsa052051.00909873
46Transcriptional misregulation in cancer_Homo sapiens_hsa052021.00435255
47DNA replication_Homo sapiens_hsa030300.99684341
48Prostate cancer_Homo sapiens_hsa052150.99608229
49Neurotrophin signaling pathway_Homo sapiens_hsa047220.97158846
50Non-homologous end-joining_Homo sapiens_hsa034500.96366496
51Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.96262727
52Steroid biosynthesis_Homo sapiens_hsa001000.96195774
53Type II diabetes mellitus_Homo sapiens_hsa049300.95573407
54Insulin secretion_Homo sapiens_hsa049110.95549759
55Viral carcinogenesis_Homo sapiens_hsa052030.93552454
56Glutamatergic synapse_Homo sapiens_hsa047240.93108829
57Base excision repair_Homo sapiens_hsa034100.92650315
58GnRH signaling pathway_Homo sapiens_hsa049120.92558188
59Morphine addiction_Homo sapiens_hsa050320.92335546
60GABAergic synapse_Homo sapiens_hsa047270.91061931
61Pathways in cancer_Homo sapiens_hsa052000.90764291
62RNA degradation_Homo sapiens_hsa030180.90247318
63Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89677167
64Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.89588308
65Oxytocin signaling pathway_Homo sapiens_hsa049210.89435503
66Olfactory transduction_Homo sapiens_hsa047400.89072496
67Small cell lung cancer_Homo sapiens_hsa052220.88509950
68Aldosterone synthesis and secretion_Homo sapiens_hsa049250.88028897
69Notch signaling pathway_Homo sapiens_hsa043300.87480276
70Phosphatidylinositol signaling system_Homo sapiens_hsa040700.87384817
71HTLV-I infection_Homo sapiens_hsa051660.86354161
72MAPK signaling pathway_Homo sapiens_hsa040100.86114863
73Renal cell carcinoma_Homo sapiens_hsa052110.85947502
74Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.85934714
75Systemic lupus erythematosus_Homo sapiens_hsa053220.85484480
76p53 signaling pathway_Homo sapiens_hsa041150.85102950
77cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84939239
78Thyroid cancer_Homo sapiens_hsa052160.84495083
79Cholinergic synapse_Homo sapiens_hsa047250.84487368
80Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.84460282
81Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.81829918
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.81821678
83Central carbon metabolism in cancer_Homo sapiens_hsa052300.81721480
84Focal adhesion_Homo sapiens_hsa045100.81477295
85Melanoma_Homo sapiens_hsa052180.80877299
86Choline metabolism in cancer_Homo sapiens_hsa052310.79383667
87Selenocompound metabolism_Homo sapiens_hsa004500.79341801
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.78891302
89cAMP signaling pathway_Homo sapiens_hsa040240.78768896
90Pancreatic cancer_Homo sapiens_hsa052120.77439898
91Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.76806062
92Insulin signaling pathway_Homo sapiens_hsa049100.76248600
93Homologous recombination_Homo sapiens_hsa034400.75681613
94Dilated cardiomyopathy_Homo sapiens_hsa054140.74079536
95Nucleotide excision repair_Homo sapiens_hsa034200.73217838
96Rap1 signaling pathway_Homo sapiens_hsa040150.73210259
97FoxO signaling pathway_Homo sapiens_hsa040680.72650857
98Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72460011
99One carbon pool by folate_Homo sapiens_hsa006700.72336563
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.72241404
101Propanoate metabolism_Homo sapiens_hsa006400.72045460
102Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.71778969
103Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.69470449
104Tight junction_Homo sapiens_hsa045300.68999188
105Cocaine addiction_Homo sapiens_hsa050300.68568078
106Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65463629
107Salivary secretion_Homo sapiens_hsa049700.65374578
108AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.65192359
109Inositol phosphate metabolism_Homo sapiens_hsa005620.64437406
110Cysteine and methionine metabolism_Homo sapiens_hsa002700.63603983
111Basal transcription factors_Homo sapiens_hsa030220.63578166
112Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.62905663
113Fatty acid biosynthesis_Homo sapiens_hsa000610.62266285
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.62097354
115Prolactin signaling pathway_Homo sapiens_hsa049170.59690022
116AMPK signaling pathway_Homo sapiens_hsa041520.59212186
117Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.57599797
118Biosynthesis of amino acids_Homo sapiens_hsa012300.54924243
119Circadian rhythm_Homo sapiens_hsa047100.53243127
120Glucagon signaling pathway_Homo sapiens_hsa049220.52268379
121Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.51345854
122Bladder cancer_Homo sapiens_hsa052190.51329429
123Pyruvate metabolism_Homo sapiens_hsa006200.51242261
124Thyroid hormone synthesis_Homo sapiens_hsa049180.46454749
125Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45414351
126Fatty acid metabolism_Homo sapiens_hsa012120.41981221

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