

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of memory T cell differentiation (GO:0043380) | 4.11708383 |
| 2 | neural tube formation (GO:0001841) | 4.05324208 |
| 3 | DNA double-strand break processing (GO:0000729) | 4.02776841 |
| 4 | DNA deamination (GO:0045006) | 3.84646225 |
| 5 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.78989550 |
| 6 | regulation of meiosis I (GO:0060631) | 3.77484927 |
| 7 | piRNA metabolic process (GO:0034587) | 3.55630775 |
| 8 | protein polyglutamylation (GO:0018095) | 3.54874924 |
| 9 | regulation of cilium movement (GO:0003352) | 3.49230359 |
| 10 | replication fork processing (GO:0031297) | 3.46525299 |
| 11 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.43392168 |
| 12 | male sex determination (GO:0030238) | 3.41956650 |
| 13 | intraciliary transport (GO:0042073) | 3.36423183 |
| 14 | epithelial cilium movement (GO:0003351) | 3.33611806 |
| 15 | photoreceptor cell maintenance (GO:0045494) | 3.29873402 |
| 16 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.28206565 |
| 17 | histone H3-K4 trimethylation (GO:0080182) | 3.27515641 |
| 18 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.24794788 |
| 19 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.24794788 |
| 20 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.24794788 |
| 21 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.21715473 |
| 22 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.21293739 |
| 23 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.21293739 |
| 24 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 3.20499240 |
| 25 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 3.20499240 |
| 26 | resolution of meiotic recombination intermediates (GO:0000712) | 3.20372287 |
| 27 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.20322269 |
| 28 | establishment of protein localization to Golgi (GO:0072600) | 3.15360848 |
| 29 | negative regulation of telomere maintenance (GO:0032205) | 3.15095321 |
| 30 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.14096038 |
| 31 | detection of light stimulus involved in visual perception (GO:0050908) | 3.14096038 |
| 32 | T-helper cell differentiation (GO:0042093) | 3.13612097 |
| 33 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.13612097 |
| 34 | cullin deneddylation (GO:0010388) | 3.13280779 |
| 35 | platelet dense granule organization (GO:0060155) | 3.12633328 |
| 36 | kidney morphogenesis (GO:0060993) | 3.11699029 |
| 37 | protein prenylation (GO:0018342) | 3.07105166 |
| 38 | prenylation (GO:0097354) | 3.07105166 |
| 39 | cilium morphogenesis (GO:0060271) | 3.06377052 |
| 40 | protein neddylation (GO:0045116) | 3.03061368 |
| 41 | protein targeting to Golgi (GO:0000042) | 3.01803973 |
| 42 | somite development (GO:0061053) | 2.99069742 |
| 43 | behavioral response to nicotine (GO:0035095) | 2.98972957 |
| 44 | protein complex biogenesis (GO:0070271) | 2.98936162 |
| 45 | histone H3-K9 methylation (GO:0051567) | 2.97847896 |
| 46 | rhodopsin mediated signaling pathway (GO:0016056) | 2.97695187 |
| 47 | proteasome assembly (GO:0043248) | 2.97476460 |
| 48 | fucose catabolic process (GO:0019317) | 2.95518009 |
| 49 | L-fucose metabolic process (GO:0042354) | 2.95518009 |
| 50 | L-fucose catabolic process (GO:0042355) | 2.95518009 |
| 51 | cilium organization (GO:0044782) | 2.95191830 |
| 52 | CD4-positive, alpha-beta T cell differentiation (GO:0043367) | 2.91290390 |
| 53 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.90716491 |
| 54 | protein localization to cilium (GO:0061512) | 2.89889037 |
| 55 | cilium assembly (GO:0042384) | 2.87275985 |
| 56 | histone H3-K9 modification (GO:0061647) | 2.86843695 |
| 57 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.84764614 |
| 58 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.84764614 |
| 59 | isotype switching (GO:0045190) | 2.84764614 |
| 60 | retinal cone cell development (GO:0046549) | 2.84141234 |
| 61 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.84032777 |
| 62 | NADH dehydrogenase complex assembly (GO:0010257) | 2.84032777 |
| 63 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.84032777 |
| 64 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.83821329 |
| 65 | positive regulation of meiosis (GO:0045836) | 2.82983790 |
| 66 | adenosine metabolic process (GO:0046085) | 2.81770327 |
| 67 | indolalkylamine metabolic process (GO:0006586) | 2.80828626 |
| 68 | protein localization to Golgi apparatus (GO:0034067) | 2.80601379 |
| 69 | eye photoreceptor cell development (GO:0042462) | 2.80405203 |
| 70 | photoreceptor cell differentiation (GO:0046530) | 2.78852157 |
| 71 | eye photoreceptor cell differentiation (GO:0001754) | 2.78852157 |
| 72 | respiratory chain complex IV assembly (GO:0008535) | 2.78409568 |
| 73 | dentate gyrus development (GO:0021542) | 2.78256929 |
| 74 | nonmotile primary cilium assembly (GO:0035058) | 2.78132615 |
| 75 | retinal rod cell development (GO:0046548) | 2.77295692 |
| 76 | peptidyl-lysine trimethylation (GO:0018023) | 2.77184385 |
| 77 | protein deneddylation (GO:0000338) | 2.76372450 |
| 78 | photoreceptor cell development (GO:0042461) | 2.75171434 |
| 79 | DNA demethylation (GO:0080111) | 2.74355783 |
| 80 | centriole replication (GO:0007099) | 2.74287492 |
| 81 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.71397868 |
| 82 | positive regulation of meiotic cell cycle (GO:0051446) | 2.71165241 |
| 83 | response to pheromone (GO:0019236) | 2.71074331 |
| 84 | desmosome organization (GO:0002934) | 2.69995600 |
| 85 | negative regulation of thymocyte apoptotic process (GO:0070244) | 2.69410717 |
| 86 | regulation of regulatory T cell differentiation (GO:0045589) | 2.68899568 |
| 87 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.68554945 |
| 88 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.67812903 |
| 89 | regulation of male gonad development (GO:2000018) | 2.67148306 |
| 90 | cilium movement (GO:0003341) | 2.66068051 |
| 91 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.65820347 |
| 92 | GPI anchor metabolic process (GO:0006505) | 2.65688888 |
| 93 | recombinational repair (GO:0000725) | 2.65006163 |
| 94 | regulation of telomere maintenance (GO:0032204) | 2.64532237 |
| 95 | positive regulation of cell fate commitment (GO:0010455) | 2.64130836 |
| 96 | double-strand break repair via homologous recombination (GO:0000724) | 2.61676685 |
| 97 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.61453342 |
| 98 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.61126176 |
| 99 | DNA methylation involved in gamete generation (GO:0043046) | 2.61028410 |
| 100 | synapsis (GO:0007129) | 2.60538181 |
| 101 | reciprocal meiotic recombination (GO:0007131) | 2.60236602 |
| 102 | reciprocal DNA recombination (GO:0035825) | 2.60236602 |
| 103 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.60034981 |
| 104 | forebrain neuron differentiation (GO:0021879) | 2.59235215 |
| 105 | protein K11-linked deubiquitination (GO:0035871) | 2.59071473 |
| 106 | regulation of somitogenesis (GO:0014807) | 2.58767901 |
| 107 | kynurenine metabolic process (GO:0070189) | 2.57579996 |
| 108 | regulation of bile acid biosynthetic process (GO:0070857) | 2.57191546 |
| 109 | CD4-positive, alpha-beta T cell activation (GO:0035710) | 2.57150841 |
| 110 | T cell differentiation involved in immune response (GO:0002292) | 2.56742737 |
| 111 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.56742737 |
| 112 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.56742737 |
| 113 | negative regulation of T cell mediated immunity (GO:0002710) | 2.54567888 |
| 114 | protein K48-linked ubiquitination (GO:0070936) | 2.54371162 |
| 115 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.53364676 |
| 116 | ADP metabolic process (GO:0046031) | 2.53074224 |
| 117 | cell differentiation involved in kidney development (GO:0061005) | 2.52940398 |
| 118 | regulation of alternative mRNA splicing, via spliceosome (GO:0000381) | 2.52921129 |
| 119 | inositol phosphate catabolic process (GO:0071545) | 2.52633847 |
| 120 | regulation of feeding behavior (GO:0060259) | 2.47006517 |
| 121 | androgen biosynthetic process (GO:0006702) | 2.46505899 |
| 122 | negative regulation of mast cell activation (GO:0033004) | 2.44404925 |
| 123 | cytochrome complex assembly (GO:0017004) | 2.43913207 |
| 124 | histone mRNA catabolic process (GO:0071044) | 2.43812159 |
| 125 | keratinocyte development (GO:0003334) | 2.43196127 |
| 126 | regulation of collateral sprouting (GO:0048670) | 2.42843534 |
| 127 | lymph vessel development (GO:0001945) | 2.42777790 |
| 128 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.42321716 |
| 129 | anterograde synaptic vesicle transport (GO:0048490) | 2.41926527 |
| 130 | ubiquinone metabolic process (GO:0006743) | 2.41719999 |
| 131 | ubiquinone biosynthetic process (GO:0006744) | 2.40081691 |
| 132 | mesenchymal cell differentiation (GO:0048762) | 2.39307544 |
| 133 | cell differentiation involved in metanephros development (GO:0072202) | 2.38628749 |
| 134 | alpha-beta T cell differentiation (GO:0046632) | 2.37461405 |
| 135 | glucocorticoid biosynthetic process (GO:0006704) | 2.36133879 |
| 136 | histone H3-K4 methylation (GO:0051568) | 2.35340476 |
| 137 | relaxation of smooth muscle (GO:0044557) | 2.35259765 |
| 138 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.34584570 |
| 139 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.34584570 |
| 140 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.33511758 |
| 141 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.33511758 |
| 142 | Sertoli cell development (GO:0060009) | 2.32483114 |
| 143 | limb bud formation (GO:0060174) | 2.32025266 |
| 144 | endocardial cushion morphogenesis (GO:0003203) | 2.29772222 |
| 145 | regulation of phospholipase A2 activity (GO:0032429) | 2.24925298 |
| 146 | pharyngeal system development (GO:0060037) | 2.23988851 |
| 147 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 2.23040023 |
| 148 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.21499461 |
| 149 | presynaptic membrane assembly (GO:0097105) | 2.20568362 |
| 150 | alpha-beta T cell activation (GO:0046631) | 2.20027799 |
| 151 | positive regulation of male gonad development (GO:2000020) | 2.18939427 |
| 152 | positive regulation of respiratory burst (GO:0060267) | 2.17718324 |
| 153 | sex determination (GO:0007530) | 2.16998426 |
| 154 | histamine secretion (GO:0001821) | 2.16887030 |
| 155 | negative regulation of norepinephrine secretion (GO:0010700) | 2.16719015 |
| 156 | negative regulation of protein autophosphorylation (GO:0031953) | 2.16610564 |
| 157 | limb development (GO:0060173) | 2.16526611 |
| 158 | appendage development (GO:0048736) | 2.16526611 |
| 159 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.15626381 |
| 160 | regulation of T cell cytokine production (GO:0002724) | 2.14234005 |
| 161 | cellular response to interleukin-15 (GO:0071350) | 2.13618880 |
| 162 | tonic smooth muscle contraction (GO:0014820) | 2.10891685 |
| 163 | tryptophan metabolic process (GO:0006568) | 2.10092003 |
| 164 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.09832305 |
| 165 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.08260401 |
| 166 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.08260401 |
| 167 | artery smooth muscle contraction (GO:0014824) | 2.08201949 |
| 168 | definitive hemopoiesis (GO:0060216) | 2.06104687 |
| 169 | startle response (GO:0001964) | 2.04967790 |
| 170 | lactate metabolic process (GO:0006089) | 2.04681448 |
| 171 | cornea development in camera-type eye (GO:0061303) | 2.03987405 |
| 172 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.03691935 |
| 173 | T-helper 1 type immune response (GO:0042088) | 2.03420264 |
| 174 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.02503988 |
| 175 | omega-hydroxylase P450 pathway (GO:0097267) | 2.02105341 |
| 176 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.01289731 |
| 177 | axoneme assembly (GO:0035082) | 2.01278768 |
| 178 | hormone catabolic process (GO:0042447) | 2.01231843 |
| 179 | nucleotide transmembrane transport (GO:1901679) | 1.98876922 |
| 180 | indole-containing compound catabolic process (GO:0042436) | 1.97748972 |
| 181 | indolalkylamine catabolic process (GO:0046218) | 1.97748972 |
| 182 | tryptophan catabolic process (GO:0006569) | 1.97748972 |
| 183 | histone lysine methylation (GO:0034968) | 1.97247765 |
| 184 | cellular response to prostaglandin stimulus (GO:0071379) | 1.96833541 |
| 185 | regulation of cardioblast proliferation (GO:0003264) | 1.96324884 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.40349029 |
| 2 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.71374299 |
| 3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.58125273 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.50186067 |
| 5 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.43079018 |
| 6 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.33228740 |
| 7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.31820856 |
| 8 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.25372615 |
| 9 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.18583362 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.17862255 |
| 11 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.16286066 |
| 12 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.15933705 |
| 13 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.15330402 |
| 14 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.11840692 |
| 15 | P300_19829295_ChIP-Seq_ESCs_Human | 1.99802307 |
| 16 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.97508786 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.94896175 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.92164137 |
| 19 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.87952286 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.83781739 |
| 21 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.83244401 |
| 22 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.82853502 |
| 23 | GATA1_22025678_ChIP-Seq_K562_Human | 1.82513278 |
| 24 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.79470781 |
| 25 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.77469222 |
| 26 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.76322416 |
| 27 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.72242857 |
| 28 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.69028380 |
| 29 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.68716122 |
| 30 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.67155312 |
| 31 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.61933623 |
| 32 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.61522469 |
| 33 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.60590769 |
| 34 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.60410596 |
| 35 | FUS_26573619_Chip-Seq_HEK293_Human | 1.60377492 |
| 36 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.59335634 |
| 37 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.56984836 |
| 38 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.56952614 |
| 39 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.56527794 |
| 40 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.56046141 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.56014762 |
| 42 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.55676384 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.55092465 |
| 44 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.55072683 |
| 45 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.54825265 |
| 46 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.52122430 |
| 47 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.51967720 |
| 48 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.51080045 |
| 49 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.49098544 |
| 50 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.49098544 |
| 51 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.48544548 |
| 52 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.48122260 |
| 53 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.46735853 |
| 54 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.45619380 |
| 55 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.43826407 |
| 56 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.43048828 |
| 57 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.42898896 |
| 58 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.42176366 |
| 59 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.41711980 |
| 60 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.40998806 |
| 61 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.40652470 |
| 62 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.40630789 |
| 63 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.40409901 |
| 64 | VDR_22108803_ChIP-Seq_LS180_Human | 1.38783889 |
| 65 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.38737103 |
| 66 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.38627278 |
| 67 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.38259611 |
| 68 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.38091300 |
| 69 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.38090174 |
| 70 | EWS_26573619_Chip-Seq_HEK293_Human | 1.38017769 |
| 71 | * EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.37089545 |
| 72 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.36816784 |
| 73 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.36563598 |
| 74 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35129021 |
| 75 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.35129021 |
| 76 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.34250696 |
| 77 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.31616729 |
| 78 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.31014310 |
| 79 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.30431786 |
| 80 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29490311 |
| 81 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.29281839 |
| 82 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.28677666 |
| 83 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.27892380 |
| 84 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.27890409 |
| 85 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.27533941 |
| 86 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.27493258 |
| 87 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.25757024 |
| 88 | AR_25329375_ChIP-Seq_VCAP_Human | 1.25226732 |
| 89 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.25149129 |
| 90 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.24357524 |
| 91 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.23635100 |
| 92 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.23303066 |
| 93 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.23157203 |
| 94 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.23075936 |
| 95 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.22999534 |
| 96 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.22779498 |
| 97 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.22779498 |
| 98 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.22768788 |
| 99 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.22659329 |
| 100 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.22473896 |
| 101 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.22223404 |
| 102 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.20772012 |
| 103 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.18980792 |
| 104 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.18970450 |
| 105 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.18771980 |
| 106 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.18734748 |
| 107 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.18665802 |
| 108 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.18166280 |
| 109 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.18105469 |
| 110 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.17853820 |
| 111 | STAT3_23295773_ChIP-Seq_U87_Human | 1.17376928 |
| 112 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.17315903 |
| 113 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.16887311 |
| 114 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.16876083 |
| 115 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.16694894 |
| 116 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.14709630 |
| 117 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.14024334 |
| 118 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.13580433 |
| 119 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.13427111 |
| 120 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.13131080 |
| 121 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.12617244 |
| 122 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.12105077 |
| 123 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.12105077 |
| 124 | * TCF4_22108803_ChIP-Seq_LS180_Human | 1.12039876 |
| 125 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12031072 |
| 126 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.11462805 |
| 127 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.11462805 |
| 128 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.11213370 |
| 129 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.10289874 |
| 130 | TCF4_23295773_ChIP-Seq_U87_Human | 1.10161656 |
| 131 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.09910799 |
| 132 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.09474912 |
| 133 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.09214043 |
| 134 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.09037302 |
| 135 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08940130 |
| 136 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.07643361 |
| 137 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.05226445 |
| 138 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.03053114 |
| 139 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.00588041 |
| 140 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.00417848 |
| 141 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.00165417 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 4.12193575 |
| 2 | MP0002009_preneoplasia | 4.12014877 |
| 3 | MP0003787_abnormal_imprinting | 3.62238627 |
| 4 | MP0001188_hyperpigmentation | 3.49284462 |
| 5 | MP0000569_abnormal_digit_pigmentation | 2.98050750 |
| 6 | MP0005551_abnormal_eye_electrophysiolog | 2.95795929 |
| 7 | MP0002102_abnormal_ear_morphology | 2.68962241 |
| 8 | MP0006072_abnormal_retinal_apoptosis | 2.48610783 |
| 9 | MP0006292_abnormal_olfactory_placode | 2.46043201 |
| 10 | MP0001984_abnormal_olfaction | 2.34611991 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.28516455 |
| 12 | MP0005423_abnormal_somatic_nervous | 2.20096759 |
| 13 | MP0002138_abnormal_hepatobiliary_system | 2.11859327 |
| 14 | MP0008058_abnormal_DNA_repair | 2.10247108 |
| 15 | MP0002139_abnormal_hepatobiliary_system | 2.08324676 |
| 16 | MP0004142_abnormal_muscle_tone | 2.05630897 |
| 17 | MP0002166_altered_tumor_susceptibility | 2.01496896 |
| 18 | MP0002837_dystrophic_cardiac_calcinosis | 2.01149215 |
| 19 | MP0002822_catalepsy | 1.98990549 |
| 20 | MP0004147_increased_porphyrin_level | 1.94012839 |
| 21 | MP0001529_abnormal_vocalization | 1.94010754 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.93937025 |
| 23 | MP0003252_abnormal_bile_duct | 1.92373659 |
| 24 | MP0005409_darkened_coat_color | 1.90982105 |
| 25 | MP0005253_abnormal_eye_physiology | 1.86424311 |
| 26 | MP0005085_abnormal_gallbladder_physiolo | 1.84045238 |
| 27 | MP0005365_abnormal_bile_salt | 1.82422880 |
| 28 | MP0003890_abnormal_embryonic-extraembry | 1.79255292 |
| 29 | MP0005646_abnormal_pituitary_gland | 1.77035366 |
| 30 | MP0000372_irregular_coat_pigmentation | 1.76311781 |
| 31 | MP0009697_abnormal_copulation | 1.75482659 |
| 32 | MP0001879_abnormal_lymphatic_vessel | 1.73985353 |
| 33 | MP0001873_stomach_inflammation | 1.73967125 |
| 34 | MP0005379_endocrine/exocrine_gland_phen | 1.73770375 |
| 35 | MP0003868_abnormal_feces_composition | 1.72549092 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.67436777 |
| 37 | MP0004133_heterotaxia | 1.60734070 |
| 38 | MP0001968_abnormal_touch/_nociception | 1.59120517 |
| 39 | MP0003724_increased_susceptibility_to | 1.57540755 |
| 40 | MP0002095_abnormal_skin_pigmentation | 1.56230231 |
| 41 | MP0010368_abnormal_lymphatic_system | 1.56113103 |
| 42 | MP0002277_abnormal_respiratory_mucosa | 1.55678024 |
| 43 | MP0002163_abnormal_gland_morphology | 1.53987116 |
| 44 | MP0002876_abnormal_thyroid_physiology | 1.52930247 |
| 45 | MP0008789_abnormal_olfactory_epithelium | 1.52773859 |
| 46 | MP0000427_abnormal_hair_cycle | 1.52639092 |
| 47 | MP0001485_abnormal_pinna_reflex | 1.50638169 |
| 48 | MP0008995_early_reproductive_senescence | 1.50233842 |
| 49 | MP0002736_abnormal_nociception_after | 1.49673455 |
| 50 | MP0005174_abnormal_tail_pigmentation | 1.48700878 |
| 51 | MP0008872_abnormal_physiological_respon | 1.47212156 |
| 52 | MP0002254_reproductive_system_inflammat | 1.45694439 |
| 53 | MP0001270_distended_abdomen | 1.45548513 |
| 54 | MP0000778_abnormal_nervous_system | 1.44623630 |
| 55 | MP0003011_delayed_dark_adaptation | 1.43908338 |
| 56 | MP0005671_abnormal_response_to | 1.43859519 |
| 57 | MP0001346_abnormal_lacrimal_gland | 1.43365484 |
| 58 | MP0003941_abnormal_skin_development | 1.42871813 |
| 59 | MP0001486_abnormal_startle_reflex | 1.41782091 |
| 60 | MP0009046_muscle_twitch | 1.36054477 |
| 61 | MP0005248_abnormal_Harderian_gland | 1.35883977 |
| 62 | MP0002006_tumorigenesis | 1.33667835 |
| 63 | MP0009745_abnormal_behavioral_response | 1.33225959 |
| 64 | MP0005084_abnormal_gallbladder_morpholo | 1.32328063 |
| 65 | MP0005645_abnormal_hypothalamus_physiol | 1.31960193 |
| 66 | MP0004381_abnormal_hair_follicle | 1.31757013 |
| 67 | MP0002272_abnormal_nervous_system | 1.31625993 |
| 68 | MP0010386_abnormal_urinary_bladder | 1.29749161 |
| 69 | MP0001790_abnormal_immune_system | 1.27483917 |
| 70 | MP0005387_immune_system_phenotype | 1.27483917 |
| 71 | MP0003195_calcinosis | 1.26527341 |
| 72 | MP0005647_abnormal_sex_gland | 1.25140289 |
| 73 | MP0002751_abnormal_autonomic_nervous | 1.23514899 |
| 74 | MP0004215_abnormal_myocardial_fiber | 1.22464972 |
| 75 | MP0002234_abnormal_pharynx_morphology | 1.18094833 |
| 76 | MP0002098_abnormal_vibrissa_morphology | 1.17455582 |
| 77 | MP0005195_abnormal_posterior_eye | 1.15442407 |
| 78 | MP0008877_abnormal_DNA_methylation | 1.13908482 |
| 79 | MP0001835_abnormal_antigen_presentation | 1.13205612 |
| 80 | MP0009780_abnormal_chondrocyte_physiolo | 1.12063123 |
| 81 | MP0001764_abnormal_homeostasis | 1.11915938 |
| 82 | MP0005386_behavior/neurological_phenoty | 1.10877371 |
| 83 | MP0004924_abnormal_behavior | 1.10877371 |
| 84 | MP0004145_abnormal_muscle_electrophysio | 1.09944042 |
| 85 | MP0002557_abnormal_social/conspecific_i | 1.09845523 |
| 86 | MP0003763_abnormal_thymus_physiology | 1.09732134 |
| 87 | MP0004019_abnormal_vitamin_homeostasis | 1.08433544 |
| 88 | MP0002928_abnormal_bile_duct | 1.07358578 |
| 89 | MP0005394_taste/olfaction_phenotype | 1.07085977 |
| 90 | MP0005499_abnormal_olfactory_system | 1.07085977 |
| 91 | MP0004782_abnormal_surfactant_physiolog | 1.06811382 |
| 92 | MP0001929_abnormal_gametogenesis | 1.05500614 |
| 93 | MP0010094_abnormal_chromosome_stability | 1.04975636 |
| 94 | MP0001293_anophthalmia | 1.01935583 |
| 95 | MP0002734_abnormal_mechanical_nocicepti | 1.01728595 |
| 96 | MP0003718_maternal_effect | 1.01403027 |
| 97 | MP0003121_genomic_imprinting | 1.00395129 |
| 98 | MP0001324_abnormal_eye_pigmentation | 1.00341365 |
| 99 | MP0002160_abnormal_reproductive_system | 1.00303403 |
| 100 | MP0001502_abnormal_circadian_rhythm | 0.99467509 |
| 101 | MP0000383_abnormal_hair_follicle | 0.99009900 |
| 102 | MP0000049_abnormal_middle_ear | 0.98460175 |
| 103 | MP0003646_muscle_fatigue | 0.97648351 |
| 104 | MP0005389_reproductive_system_phenotype | 0.95333791 |
| 105 | MP0002210_abnormal_sex_determination | 0.95308997 |
| 106 | MP0000653_abnormal_sex_gland | 0.95145495 |
| 107 | MP0002638_abnormal_pupillary_reflex | 0.94759271 |
| 108 | MP0000647_abnormal_sebaceous_gland | 0.94208708 |
| 109 | MP0002572_abnormal_emotion/affect_behav | 0.93236185 |
| 110 | MP0000631_abnormal_neuroendocrine_gland | 0.92754983 |
| 111 | MP0002090_abnormal_vision | 0.92719775 |
| 112 | MP0001119_abnormal_female_reproductive | 0.92065924 |
| 113 | MP0005391_vision/eye_phenotype | 0.91224406 |
| 114 | MP0003786_premature_aging | 0.91190409 |
| 115 | MP0001286_abnormal_eye_development | 0.90799449 |
| 116 | MP0003698_abnormal_male_reproductive | 0.90346477 |
| 117 | MP0004043_abnormal_pH_regulation | 0.89419093 |
| 118 | MP0009764_decreased_sensitivity_to | 0.88940961 |
| 119 | MP0005187_abnormal_penis_morphology | 0.88061271 |
| 120 | MP0002067_abnormal_sensory_capabilities | 0.85999076 |
| 121 | MP0003567_abnormal_fetal_cardiomyocyte | 0.85493896 |
| 122 | MP0000465_gastrointestinal_hemorrhage | 0.84913148 |
| 123 | MP0001970_abnormal_pain_threshold | 0.83906062 |
| 124 | MP0000579_abnormal_nail_morphology | 0.83878719 |
| 125 | MP0004270_analgesia | 0.82800197 |
| 126 | MP0002933_joint_inflammation | 0.82115137 |
| 127 | MP0006035_abnormal_mitochondrial_morpho | 0.81080482 |
| 128 | MP0002752_abnormal_somatic_nervous | 0.80795361 |
| 129 | MP0001800_abnormal_humoral_immune | 0.80559123 |
| 130 | MP0005310_abnormal_salivary_gland | 0.80336861 |
| 131 | MP0003315_abnormal_perineum_morphology | 0.79232069 |
| 132 | MP0002735_abnormal_chemical_nociception | 0.78160396 |
| 133 | MP0001145_abnormal_male_reproductive | 0.78084652 |
| 134 | MP0001177_atelectasis | 0.77648667 |
| 135 | MP0002938_white_spotting | 0.77065909 |
| 136 | MP0003283_abnormal_digestive_organ | 0.76585687 |
| 137 | MP0000015_abnormal_ear_pigmentation | 0.76573855 |
| 138 | MP0001666_abnormal_nutrient_absorption | 0.75995286 |
| 139 | MP0001501_abnormal_sleep_pattern | 0.75552068 |
| 140 | MP0000613_abnormal_salivary_gland | 0.73745903 |
| 141 | MP0003943_abnormal_hepatobiliary_system | 0.73096520 |
| 142 | MP0006054_spinal_hemorrhage | 0.72827676 |
| 143 | MP0008775_abnormal_heart_ventricle | 0.72746159 |
| 144 | MP0003937_abnormal_limbs/digits/tail_de | 0.72349919 |
| 145 | MP0006036_abnormal_mitochondrial_physio | 0.71970249 |
| 146 | MP0009379_abnormal_foot_pigmentation | 0.71909161 |
| 147 | MP0003136_yellow_coat_color | 0.71560382 |
| 148 | MP0000762_abnormal_tongue_morphology | 0.71082147 |
| 149 | MP0010678_abnormal_skin_adnexa | 0.70320930 |
| 150 | MP0002249_abnormal_larynx_morphology | 0.69690062 |
| 151 | MP0004885_abnormal_endolymph | 0.69578193 |
| 152 | MP0002653_abnormal_ependyma_morphology | 0.69378438 |
| 153 | MP0001851_eye_inflammation | 0.67138249 |
| 154 | MP0003878_abnormal_ear_physiology | 0.67095032 |
| 155 | MP0005377_hearing/vestibular/ear_phenot | 0.67095032 |
| 156 | MP0004134_abnormal_chest_morphology | 0.65779239 |
| 157 | MP0009785_altered_susceptibility_to | 0.64853110 |
| 158 | MP0004742_abnormal_vestibular_system | 0.63434309 |
| 159 | MP0002723_abnormal_immune_serum | 0.62091847 |
| 160 | MP0000026_abnormal_inner_ear | 0.62020215 |
| 161 | MP0003122_maternal_imprinting | 0.61528807 |
| 162 | MP0006276_abnormal_autonomic_nervous | 0.61293439 |
| 163 | MP0003880_abnormal_central_pattern | 0.60142045 |
| 164 | MP0008004_abnormal_stomach_pH | 0.59867886 |
| 165 | MP0008961_abnormal_basal_metabolism | 0.58543560 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Congenital stationary night blindness (HP:0007642) | 4.48007415 |
| 2 | Lip pit (HP:0100267) | 4.09278577 |
| 3 | Thyroiditis (HP:0100646) | 3.44602428 |
| 4 | Nephronophthisis (HP:0000090) | 3.36912247 |
| 5 | Severe combined immunodeficiency (HP:0004430) | 3.34988367 |
| 6 | Abnormality of the fingertips (HP:0001211) | 3.30777358 |
| 7 | B lymphocytopenia (HP:0010976) | 3.18320323 |
| 8 | Decreased central vision (HP:0007663) | 3.05929874 |
| 9 | Abnormality of B cell number (HP:0010975) | 3.00718221 |
| 10 | Conjugated hyperbilirubinemia (HP:0002908) | 2.91166691 |
| 11 | Abolished electroretinogram (ERG) (HP:0000550) | 2.86852419 |
| 12 | Gait imbalance (HP:0002141) | 2.84509445 |
| 13 | Absent eyebrow (HP:0002223) | 2.83920963 |
| 14 | Alveolar cell carcinoma (HP:0006519) | 2.82545087 |
| 15 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.82159337 |
| 16 | Severe visual impairment (HP:0001141) | 2.78566491 |
| 17 | Type II lissencephaly (HP:0007260) | 2.76746115 |
| 18 | Increased corneal curvature (HP:0100692) | 2.76110623 |
| 19 | Keratoconus (HP:0000563) | 2.76110623 |
| 20 | Hypoproteinemia (HP:0003075) | 2.73795524 |
| 21 | Enlarged kidneys (HP:0000105) | 2.67188978 |
| 22 | Protruding tongue (HP:0010808) | 2.65533921 |
| 23 | Vitreoretinal degeneration (HP:0000655) | 2.65438884 |
| 24 | Pigmentary retinal degeneration (HP:0001146) | 2.61253237 |
| 25 | True hermaphroditism (HP:0010459) | 2.61133911 |
| 26 | Abnormal hair whorl (HP:0010721) | 2.59729607 |
| 27 | Combined immunodeficiency (HP:0005387) | 2.53908347 |
| 28 | Abnormality of incisor morphology (HP:0011063) | 2.53355722 |
| 29 | Thyroid-stimulating hormone excess (HP:0002925) | 2.53349405 |
| 30 | Chorioretinal atrophy (HP:0000533) | 2.52614330 |
| 31 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.46980507 |
| 32 | Intestinal atresia (HP:0011100) | 2.43434691 |
| 33 | Progressive inability to walk (HP:0002505) | 2.42964593 |
| 34 | Methylmalonic acidemia (HP:0002912) | 2.42707673 |
| 35 | Chronic hepatic failure (HP:0100626) | 2.38302172 |
| 36 | Genital tract atresia (HP:0001827) | 2.37811667 |
| 37 | Prolonged partial thromboplastin time (HP:0003645) | 2.37381054 |
| 38 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.34329263 |
| 39 | Midline defect of the nose (HP:0004122) | 2.33890863 |
| 40 | Congenital sensorineural hearing impairment (HP:0008527) | 2.33497237 |
| 41 | Bifid tongue (HP:0010297) | 2.32140992 |
| 42 | Panhypogammaglobulinemia (HP:0003139) | 2.31715589 |
| 43 | Median cleft lip (HP:0000161) | 2.31586533 |
| 44 | Hypothermia (HP:0002045) | 2.29409490 |
| 45 | Vaginal atresia (HP:0000148) | 2.28561008 |
| 46 | Abnormality of the columella (HP:0009929) | 2.27324924 |
| 47 | Anal stenosis (HP:0002025) | 2.23179075 |
| 48 | Stomach cancer (HP:0012126) | 2.21400710 |
| 49 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.20322156 |
| 50 | Fair hair (HP:0002286) | 2.17606476 |
| 51 | Tubulointerstitial nephritis (HP:0001970) | 2.17139613 |
| 52 | Colon cancer (HP:0003003) | 2.16812694 |
| 53 | Cystic liver disease (HP:0006706) | 2.15364557 |
| 54 | Abnormality of the nasal septum (HP:0000419) | 2.13679298 |
| 55 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.12528228 |
| 56 | Hyperventilation (HP:0002883) | 2.11645532 |
| 57 | Congenital hepatic fibrosis (HP:0002612) | 2.09497316 |
| 58 | Abnormality of eosinophils (HP:0001879) | 2.07984930 |
| 59 | Renal dysplasia (HP:0000110) | 2.07895416 |
| 60 | Anencephaly (HP:0002323) | 2.06892130 |
| 61 | Attenuation of retinal blood vessels (HP:0007843) | 2.06653632 |
| 62 | Inability to walk (HP:0002540) | 2.06157592 |
| 63 | Sclerocornea (HP:0000647) | 2.04276253 |
| 64 | Abnormality of the lacrimal duct (HP:0011481) | 2.04211920 |
| 65 | Progressive macrocephaly (HP:0004481) | 2.04198312 |
| 66 | Renal cortical cysts (HP:0000803) | 2.03784333 |
| 67 | Pendular nystagmus (HP:0012043) | 2.03455473 |
| 68 | Abnormality of macular pigmentation (HP:0008002) | 2.02936981 |
| 69 | Short tibia (HP:0005736) | 2.02631634 |
| 70 | Biliary tract neoplasm (HP:0100574) | 2.01358692 |
| 71 | Abnormality of chromosome stability (HP:0003220) | 2.00933364 |
| 72 | Male pseudohermaphroditism (HP:0000037) | 1.99473455 |
| 73 | Metaphyseal dysplasia (HP:0100255) | 1.99432493 |
| 74 | Postaxial hand polydactyly (HP:0001162) | 1.99151609 |
| 75 | Exotropia (HP:0000577) | 1.98261826 |
| 76 | IgG deficiency (HP:0004315) | 1.98204734 |
| 77 | Glioma (HP:0009733) | 1.97811496 |
| 78 | Renal hypoplasia (HP:0000089) | 1.96664447 |
| 79 | Hyperkalemia (HP:0002153) | 1.95999415 |
| 80 | Neonatal hypoglycemia (HP:0001998) | 1.95738168 |
| 81 | Increased CSF lactate (HP:0002490) | 1.95718038 |
| 82 | Bifid scrotum (HP:0000048) | 1.95639187 |
| 83 | Hepatic necrosis (HP:0002605) | 1.95152129 |
| 84 | Aplasia cutis congenita (HP:0001057) | 1.95117886 |
| 85 | Acute necrotizing encephalopathy (HP:0006965) | 1.94718407 |
| 86 | Broad-based gait (HP:0002136) | 1.94605863 |
| 87 | Poor coordination (HP:0002370) | 1.93992043 |
| 88 | Mitochondrial inheritance (HP:0001427) | 1.93336975 |
| 89 | Parakeratosis (HP:0001036) | 1.93275159 |
| 90 | Epileptic encephalopathy (HP:0200134) | 1.93241911 |
| 91 | Cupped ear (HP:0000378) | 1.93085046 |
| 92 | Medial flaring of the eyebrow (HP:0010747) | 1.92864718 |
| 93 | Prolonged bleeding time (HP:0003010) | 1.92516581 |
| 94 | Febrile seizures (HP:0002373) | 1.92343914 |
| 95 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.91964136 |
| 96 | Chronic diarrhea (HP:0002028) | 1.91703527 |
| 97 | Agammaglobulinemia (HP:0004432) | 1.91044026 |
| 98 | Ependymoma (HP:0002888) | 1.91017370 |
| 99 | Eosinophilia (HP:0001880) | 1.90989484 |
| 100 | Absent speech (HP:0001344) | 1.90974464 |
| 101 | Molar tooth sign on MRI (HP:0002419) | 1.90201351 |
| 102 | Abnormality of midbrain morphology (HP:0002418) | 1.90201351 |
| 103 | Abnormality of the nasolacrimal system (HP:0000614) | 1.89955755 |
| 104 | Osteomalacia (HP:0002749) | 1.89794368 |
| 105 | Abnormal biliary tract physiology (HP:0012439) | 1.88510105 |
| 106 | Bile duct proliferation (HP:0001408) | 1.88510105 |
| 107 | 3-Methylglutaconic aciduria (HP:0003535) | 1.88432195 |
| 108 | Furrowed tongue (HP:0000221) | 1.88346687 |
| 109 | Nasolacrimal duct obstruction (HP:0000579) | 1.86167488 |
| 110 | Macular degeneration (HP:0000608) | 1.85469351 |
| 111 | Tubular atrophy (HP:0000092) | 1.84044376 |
| 112 | Hypoplasia of the thymus (HP:0000778) | 1.83924494 |
| 113 | Abnormality of secondary sexual hair (HP:0009888) | 1.83577056 |
| 114 | Abnormality of the axillary hair (HP:0100134) | 1.83577056 |
| 115 | Lissencephaly (HP:0001339) | 1.83562432 |
| 116 | IgM deficiency (HP:0002850) | 1.81885664 |
| 117 | Medulloblastoma (HP:0002885) | 1.81176509 |
| 118 | Amelogenesis imperfecta (HP:0000705) | 1.79940230 |
| 119 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.79694194 |
| 120 | Pancreatic cysts (HP:0001737) | 1.79676537 |
| 121 | Gaze-evoked nystagmus (HP:0000640) | 1.79236464 |
| 122 | Acute encephalopathy (HP:0006846) | 1.79209260 |
| 123 | Cerebellar dysplasia (HP:0007033) | 1.78931106 |
| 124 | Fibular hypoplasia (HP:0003038) | 1.78285438 |
| 125 | Septo-optic dysplasia (HP:0100842) | 1.77849453 |
| 126 | Methylmalonic aciduria (HP:0012120) | 1.76802286 |
| 127 | Central scotoma (HP:0000603) | 1.76220610 |
| 128 | Supernumerary spleens (HP:0009799) | 1.76216415 |
| 129 | Abnormality of the renal cortex (HP:0011035) | 1.76002440 |
| 130 | Abnormality of the labia minora (HP:0012880) | 1.75943751 |
| 131 | Volvulus (HP:0002580) | 1.75610117 |
| 132 | Abnormality of the incisor (HP:0000676) | 1.75362670 |
| 133 | Hepatocellular necrosis (HP:0001404) | 1.73080812 |
| 134 | Preaxial hand polydactyly (HP:0001177) | 1.72972691 |
| 135 | Optic nerve hypoplasia (HP:0000609) | 1.72323168 |
| 136 | Pancreatic fibrosis (HP:0100732) | 1.72139781 |
| 137 | Genetic anticipation (HP:0003743) | 1.71882166 |
| 138 | Abnormality of the renal medulla (HP:0100957) | 1.71355118 |
| 139 | Recurrent sinusitis (HP:0011108) | 1.71178153 |
| 140 | Pachygyria (HP:0001302) | 1.70661869 |
| 141 | Narrow forehead (HP:0000341) | 1.70461071 |
| 142 | Abnormality of the pons (HP:0007361) | 1.70408374 |
| 143 | Hypophosphatemic rickets (HP:0004912) | 1.69134408 |
| 144 | Progressive cerebellar ataxia (HP:0002073) | 1.68820981 |
| 145 | Congenital primary aphakia (HP:0007707) | 1.68782816 |
| 146 | Astigmatism (HP:0000483) | 1.68521101 |
| 147 | Overfolded helix (HP:0000396) | 1.68250217 |
| 148 | Abnormal ciliary motility (HP:0012262) | 1.68067293 |
| 149 | Dandy-Walker malformation (HP:0001305) | 1.67000423 |
| 150 | Dyschromatopsia (HP:0007641) | 1.65944918 |
| 151 | Abnormality of the ileum (HP:0001549) | 1.65311381 |
| 152 | Azoospermia (HP:0000027) | 1.64881306 |
| 153 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.64736665 |
| 154 | Abnormality of alanine metabolism (HP:0010916) | 1.64736665 |
| 155 | Hyperalaninemia (HP:0003348) | 1.64736665 |
| 156 | Prostate neoplasm (HP:0100787) | 1.64038355 |
| 157 | Gonadotropin excess (HP:0000837) | 1.63978832 |
| 158 | Amyotrophic lateral sclerosis (HP:0007354) | 1.63884575 |
| 159 | Hypoplasia of the pons (HP:0012110) | 1.63503705 |
| 160 | Drooling (HP:0002307) | 1.63486645 |
| 161 | Type 2 muscle fiber atrophy (HP:0003554) | 1.63289093 |
| 162 | Retrobulbar optic neuritis (HP:0100654) | 1.63201131 |
| 163 | Optic neuritis (HP:0100653) | 1.63201131 |
| 164 | Blue irides (HP:0000635) | 1.63029851 |
| 165 | Meckel diverticulum (HP:0002245) | 1.62997483 |
| 166 | Abnormality of chloride homeostasis (HP:0011422) | 1.61793886 |
| 167 | Nephrogenic diabetes insipidus (HP:0009806) | 1.61156720 |
| 168 | Abnormality of the fibula (HP:0002991) | 1.60407620 |
| 169 | Mixed hearing impairment (HP:0000410) | 1.60166332 |
| 170 | Abnormality of the intervertebral disk (HP:0005108) | 1.59853981 |
| 171 | Postaxial foot polydactyly (HP:0001830) | 1.59575310 |
| 172 | Cutaneous finger syndactyly (HP:0010554) | 1.58634074 |
| 173 | Gingival bleeding (HP:0000225) | 1.58507102 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 3.42146976 |
| 2 | CASK | 3.11357666 |
| 3 | INSRR | 2.60515374 |
| 4 | TXK | 2.24029006 |
| 5 | MAP3K14 | 2.22096038 |
| 6 | BMPR1B | 2.14581565 |
| 7 | IRAK1 | 2.12984263 |
| 8 | MST1R | 2.10162010 |
| 9 | BCR | 2.06593978 |
| 10 | GRK1 | 1.99656663 |
| 11 | TRIM28 | 1.99106816 |
| 12 | EPHA3 | 1.97976900 |
| 13 | NUAK1 | 1.95044003 |
| 14 | MST4 | 1.89292230 |
| 15 | EIF2AK3 | 1.88301601 |
| 16 | PIK3CA | 1.77440201 |
| 17 | TNIK | 1.75820051 |
| 18 | MKNK2 | 1.67900227 |
| 19 | CAMK1G | 1.66485650 |
| 20 | TAOK3 | 1.66272275 |
| 21 | CDK3 | 1.65206116 |
| 22 | AKT3 | 1.62140808 |
| 23 | MAPK15 | 1.61589201 |
| 24 | SGK2 | 1.59745621 |
| 25 | SIK3 | 1.56356285 |
| 26 | ACVR1B | 1.52949856 |
| 27 | TIE1 | 1.51540054 |
| 28 | GRK7 | 1.47501521 |
| 29 | PLK2 | 1.41022509 |
| 30 | FGFR3 | 1.36359987 |
| 31 | IRAK2 | 1.34135907 |
| 32 | LATS1 | 1.32977548 |
| 33 | JAK3 | 1.29160232 |
| 34 | IRAK3 | 1.28450045 |
| 35 | NEK6 | 1.27805619 |
| 36 | MUSK | 1.27442240 |
| 37 | BRD4 | 1.25964781 |
| 38 | CSNK1G2 | 1.24027394 |
| 39 | STK16 | 1.23128069 |
| 40 | WNK3 | 1.22986961 |
| 41 | IKBKE | 1.22455961 |
| 42 | CSNK1G3 | 1.21077825 |
| 43 | CDK8 | 1.20548858 |
| 44 | CAMK1D | 1.19972010 |
| 45 | IRAK4 | 1.18640306 |
| 46 | CSNK1A1L | 1.17564127 |
| 47 | CSNK1G1 | 1.17066723 |
| 48 | FRK | 1.14272936 |
| 49 | SGK223 | 1.13100063 |
| 50 | SGK494 | 1.13100063 |
| 51 | TEC | 1.11465344 |
| 52 | MAP3K12 | 1.08703634 |
| 53 | MAPK7 | 1.04331635 |
| 54 | BMPR2 | 1.03247268 |
| 55 | SGK3 | 1.03123973 |
| 56 | CDK9 | 1.03035368 |
| 57 | TGFBR2 | 1.01438439 |
| 58 | YES1 | 0.99693756 |
| 59 | DYRK2 | 0.98369746 |
| 60 | MKNK1 | 0.97135698 |
| 61 | DYRK1A | 0.96724284 |
| 62 | PINK1 | 0.94981138 |
| 63 | PAK3 | 0.93709462 |
| 64 | ERBB3 | 0.90806760 |
| 65 | VRK1 | 0.90635265 |
| 66 | MAP2K7 | 0.90262088 |
| 67 | ADRBK2 | 0.88645132 |
| 68 | JAK1 | 0.88505175 |
| 69 | BCKDK | 0.87408146 |
| 70 | STK24 | 0.85982661 |
| 71 | PLK3 | 0.85253360 |
| 72 | NME1 | 0.84745522 |
| 73 | PLK4 | 0.82959455 |
| 74 | PRKAA2 | 0.81216733 |
| 75 | DYRK3 | 0.78616618 |
| 76 | EPHA4 | 0.78615259 |
| 77 | WNK1 | 0.76473001 |
| 78 | WNK4 | 0.75528253 |
| 79 | PNCK | 0.74975054 |
| 80 | PKN1 | 0.73522913 |
| 81 | ADRBK1 | 0.72831207 |
| 82 | CHUK | 0.72767553 |
| 83 | CDK12 | 0.70775222 |
| 84 | BTK | 0.70005298 |
| 85 | MARK1 | 0.69788924 |
| 86 | FER | 0.69700580 |
| 87 | FGFR4 | 0.68683280 |
| 88 | MAP4K1 | 0.67047884 |
| 89 | FGFR2 | 0.66147754 |
| 90 | TNK2 | 0.65917784 |
| 91 | TYK2 | 0.65209880 |
| 92 | STK38L | 0.64305192 |
| 93 | NLK | 0.64300198 |
| 94 | WEE1 | 0.61777056 |
| 95 | MARK3 | 0.60973964 |
| 96 | PRKCE | 0.60168834 |
| 97 | ZAK | 0.59459913 |
| 98 | TLK1 | 0.59369115 |
| 99 | IKBKB | 0.58699529 |
| 100 | KIT | 0.55624176 |
| 101 | CAMKK2 | 0.55451859 |
| 102 | EPHB2 | 0.54544454 |
| 103 | STK3 | 0.54536211 |
| 104 | EIF2AK1 | 0.54385778 |
| 105 | PHKG1 | 0.54131631 |
| 106 | PHKG2 | 0.54131631 |
| 107 | PRKCQ | 0.53744458 |
| 108 | PLK1 | 0.53531188 |
| 109 | BRSK2 | 0.53453536 |
| 110 | CDK19 | 0.53416651 |
| 111 | MAP3K2 | 0.53390194 |
| 112 | SGK1 | 0.53075304 |
| 113 | MAPK13 | 0.52186997 |
| 114 | RIPK4 | 0.51786979 |
| 115 | MAPKAPK3 | 0.51749010 |
| 116 | MAP3K5 | 0.51122099 |
| 117 | PRPF4B | 0.49959361 |
| 118 | LCK | 0.49807647 |
| 119 | CLK1 | 0.49484220 |
| 120 | MAPK12 | 0.48494703 |
| 121 | MELK | 0.47969453 |
| 122 | CCNB1 | 0.47548507 |
| 123 | PTK2B | 0.47524516 |
| 124 | HIPK2 | 0.47484840 |
| 125 | OXSR1 | 0.47224429 |
| 126 | ITK | 0.47107432 |
| 127 | PRKCG | 0.47006455 |
| 128 | MAP3K4 | 0.46953236 |
| 129 | CAMK4 | 0.46773553 |
| 130 | ATM | 0.44976221 |
| 131 | PRKG1 | 0.44451064 |
| 132 | CAMK2A | 0.44087122 |
| 133 | TBK1 | 0.43812776 |
| 134 | SIK2 | 0.43414812 |
| 135 | NEK9 | 0.41919636 |
| 136 | TGFBR1 | 0.41708010 |
| 137 | STK39 | 0.40386216 |
| 138 | IGF1R | 0.39653227 |
| 139 | ATR | 0.39454556 |
| 140 | MAP2K6 | 0.39432308 |
| 141 | PDK2 | 0.39208817 |
| 142 | SRPK1 | 0.38890144 |
| 143 | CSNK1A1 | 0.38390235 |
| 144 | MATK | 0.38298833 |
| 145 | CDC7 | 0.37771247 |
| 146 | CSNK1D | 0.37539301 |
| 147 | MAP3K7 | 0.37107856 |
| 148 | SYK | 0.35924223 |
| 149 | OBSCN | 0.35044673 |
| 150 | MINK1 | 0.34722133 |
| 151 | MAP2K4 | 0.34593335 |
| 152 | PIK3CG | 0.34178454 |
| 153 | PRKACA | 0.34087549 |
| 154 | ERBB2 | 0.33092508 |
| 155 | RPS6KA5 | 0.32153631 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Phototransduction_Homo sapiens_hsa04744 | 3.69338030 |
| 2 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.70993916 |
| 3 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.66831898 |
| 4 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.55248176 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 2.39847192 |
| 6 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.36955772 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.33368249 |
| 8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.31528985 |
| 9 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.25691400 |
| 10 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.17316063 |
| 11 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.09463233 |
| 12 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 2.08628620 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.07404367 |
| 14 | Circadian rhythm_Homo sapiens_hsa04710 | 2.06350838 |
| 15 | Proteasome_Homo sapiens_hsa03050 | 2.04214474 |
| 16 | Mismatch repair_Homo sapiens_hsa03430 | 1.93010025 |
| 17 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.90904065 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.88855032 |
| 19 | Parkinsons disease_Homo sapiens_hsa05012 | 1.85632026 |
| 20 | Lysine degradation_Homo sapiens_hsa00310 | 1.82040887 |
| 21 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.81147744 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.77997131 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.73818402 |
| 24 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.73477093 |
| 25 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.68351004 |
| 26 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.67608042 |
| 27 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.64313277 |
| 28 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.63595129 |
| 29 | RNA polymerase_Homo sapiens_hsa03020 | 1.62841979 |
| 30 | Retinol metabolism_Homo sapiens_hsa00830 | 1.55665969 |
| 31 | ABC transporters_Homo sapiens_hsa02010 | 1.54149356 |
| 32 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.47035377 |
| 33 | Nicotine addiction_Homo sapiens_hsa05033 | 1.38220687 |
| 34 | Taste transduction_Homo sapiens_hsa04742 | 1.33482258 |
| 35 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.33342552 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.33038328 |
| 37 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.32883299 |
| 38 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.29624926 |
| 39 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.27621416 |
| 40 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.25908481 |
| 41 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.24545852 |
| 42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.23249266 |
| 43 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.22392629 |
| 44 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.21549951 |
| 45 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.19103873 |
| 46 | Morphine addiction_Homo sapiens_hsa05032 | 1.16245501 |
| 47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.15799533 |
| 48 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.15308390 |
| 49 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.14526755 |
| 50 | Huntingtons disease_Homo sapiens_hsa05016 | 1.12348799 |
| 51 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.10869898 |
| 52 | Alzheimers disease_Homo sapiens_hsa05010 | 1.10009773 |
| 53 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.07765480 |
| 54 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.07578552 |
| 55 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.04849739 |
| 56 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.04721079 |
| 57 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.02887482 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 1.02724038 |
| 59 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.01773535 |
| 60 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.97771955 |
| 61 | Protein export_Homo sapiens_hsa03060 | 0.97458437 |
| 62 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.96922595 |
| 63 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.95719066 |
| 64 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.95444206 |
| 65 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.95223372 |
| 66 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.95213005 |
| 67 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.94978890 |
| 68 | Histidine metabolism_Homo sapiens_hsa00340 | 0.93538590 |
| 69 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.91795252 |
| 70 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.91589358 |
| 71 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.90185303 |
| 72 | Allograft rejection_Homo sapiens_hsa05330 | 0.88747982 |
| 73 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.87481775 |
| 74 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.85395545 |
| 75 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84995035 |
| 76 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.84592336 |
| 77 | Circadian entrainment_Homo sapiens_hsa04713 | 0.83537397 |
| 78 | GABAergic synapse_Homo sapiens_hsa04727 | 0.83343015 |
| 79 | RNA transport_Homo sapiens_hsa03013 | 0.79895715 |
| 80 | Mineral absorption_Homo sapiens_hsa04978 | 0.78440073 |
| 81 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.77362632 |
| 82 | Purine metabolism_Homo sapiens_hsa00230 | 0.76384001 |
| 83 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.76119378 |
| 84 | Measles_Homo sapiens_hsa05162 | 0.74782053 |
| 85 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.74150717 |
| 86 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.72582060 |
| 87 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.71686495 |
| 88 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.71148883 |
| 89 | Renin secretion_Homo sapiens_hsa04924 | 0.70047648 |
| 90 | Olfactory transduction_Homo sapiens_hsa04740 | 0.69502266 |
| 91 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.68877532 |
| 92 | Hepatitis C_Homo sapiens_hsa05160 | 0.67413944 |
| 93 | Leishmaniasis_Homo sapiens_hsa05140 | 0.66769730 |
| 94 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.66716430 |
| 95 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.66023397 |
| 96 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.65929234 |
| 97 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.65344055 |
| 98 | Base excision repair_Homo sapiens_hsa03410 | 0.65308204 |
| 99 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.64904204 |
| 100 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.64818225 |
| 101 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.63772020 |
| 102 | Insulin secretion_Homo sapiens_hsa04911 | 0.63671498 |
| 103 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.62473012 |
| 104 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.61979283 |
| 105 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.61961659 |
| 106 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.61055422 |
| 107 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.60459779 |
| 108 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.59607523 |
| 109 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.57595397 |
| 110 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.56788156 |
| 111 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.56344990 |
| 112 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.55949291 |
| 113 | Prostate cancer_Homo sapiens_hsa05215 | 0.53972561 |
| 114 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.53440989 |
| 115 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.52977377 |
| 116 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.52787717 |
| 117 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.52676754 |
| 118 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52530822 |
| 119 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.51993659 |
| 120 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.51843886 |
| 121 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.51448789 |
| 122 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.51440983 |
| 123 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.50676240 |
| 124 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.50283851 |
| 125 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.49489850 |
| 126 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.48572619 |
| 127 | Influenza A_Homo sapiens_hsa05164 | 0.48511138 |
| 128 | Metabolic pathways_Homo sapiens_hsa01100 | 0.48328777 |
| 129 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.47445214 |
| 130 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.47389059 |
| 131 | Axon guidance_Homo sapiens_hsa04360 | 0.47298377 |
| 132 | Long-term depression_Homo sapiens_hsa04730 | 0.46987178 |
| 133 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.46393382 |
| 134 | Asthma_Homo sapiens_hsa05310 | 0.44872889 |
| 135 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.43420315 |
| 136 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.43009348 |
| 137 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42844885 |
| 138 | Spliceosome_Homo sapiens_hsa03040 | 0.42663412 |
| 139 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.42043131 |
| 140 | Cocaine addiction_Homo sapiens_hsa05030 | 0.41855668 |
| 141 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.39641106 |
| 142 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.39411393 |
| 143 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.39270525 |
| 144 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.38004384 |
| 145 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.31343353 |
| 146 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.28514568 |
| 147 | DNA replication_Homo sapiens_hsa03030 | 0.26162245 |

