ZMYND11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1locomotory exploration behavior (GO:0035641)4.71912601
2synaptic vesicle maturation (GO:0016188)4.55726626
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.54466238
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.30972345
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.29497570
6vocalization behavior (GO:0071625)4.20461386
7layer formation in cerebral cortex (GO:0021819)4.18723240
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.05544724
9synaptic vesicle exocytosis (GO:0016079)3.91002854
10regulation of glutamate receptor signaling pathway (GO:1900449)3.81392283
11dendritic spine morphogenesis (GO:0060997)3.74719704
12regulation of synaptic vesicle exocytosis (GO:2000300)3.74519674
13glutamate secretion (GO:0014047)3.73184996
14synaptic vesicle docking involved in exocytosis (GO:0016081)3.73027329
15regulation of synapse structural plasticity (GO:0051823)3.61020484
16ionotropic glutamate receptor signaling pathway (GO:0035235)3.54055457
17exploration behavior (GO:0035640)3.50625286
18protein localization to synapse (GO:0035418)3.49527512
19activation of protein kinase A activity (GO:0034199)3.45573670
20membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.41840792
21cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.36092957
22cellular potassium ion homeostasis (GO:0030007)3.34481513
23positive regulation of synapse maturation (GO:0090129)3.30384185
24neurotransmitter secretion (GO:0007269)3.30226158
25neurotransmitter-gated ion channel clustering (GO:0072578)3.29721453
26regulation of synaptic vesicle transport (GO:1902803)3.23760207
27sodium ion export (GO:0071436)3.23055877
28neuron cell-cell adhesion (GO:0007158)3.22893883
29glutamate receptor signaling pathway (GO:0007215)3.22531017
30regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.21098590
31dendrite morphogenesis (GO:0048813)3.21033216
32regulation of neuronal synaptic plasticity (GO:0048168)3.20652312
33cell communication by electrical coupling (GO:0010644)3.20558018
34regulation of long-term neuronal synaptic plasticity (GO:0048169)3.16306427
35neuron recognition (GO:0008038)3.15222015
36regulation of dendritic spine morphogenesis (GO:0061001)3.08865698
37long-term memory (GO:0007616)3.06843968
38synaptic transmission, glutamatergic (GO:0035249)3.01969780
39axonal fasciculation (GO:0007413)2.98515750
40neuronal action potential propagation (GO:0019227)2.95814623
41regulation of excitatory postsynaptic membrane potential (GO:0060079)2.95092629
42cerebellar Purkinje cell differentiation (GO:0021702)2.92655405
43proline transport (GO:0015824)2.90157383
44establishment of nucleus localization (GO:0040023)2.88425998
45embryonic retina morphogenesis in camera-type eye (GO:0060059)2.84401981
46neuron-neuron synaptic transmission (GO:0007270)2.82686820
47regulation of postsynaptic membrane potential (GO:0060078)2.80208157
48membrane depolarization during action potential (GO:0086010)2.78788694
49macroautophagy (GO:0016236)2.78633327
50positive regulation of vascular permeability (GO:0043117)2.78591486
51gamma-aminobutyric acid transport (GO:0015812)2.77893206
52potassium ion import (GO:0010107)2.77199321
53neuromuscular process controlling balance (GO:0050885)2.76981122
54regulation of ARF protein signal transduction (GO:0032012)2.75908925
55positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.75822723
56auditory behavior (GO:0031223)2.72867566
57positive regulation of membrane potential (GO:0045838)2.72620041
58cell communication involved in cardiac conduction (GO:0086065)2.72471585
59G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.72112673
60positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.71349837
61prepulse inhibition (GO:0060134)2.69949731
62vesicle transport along microtubule (GO:0047496)2.69482657
63regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.68674411
64regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68324620
65cerebellar granule cell differentiation (GO:0021707)2.66961214
66regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.66334936
67regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.66232379
68dendritic spine organization (GO:0097061)2.65974858
69long-term synaptic potentiation (GO:0060291)2.65820579
70negative regulation of cytosolic calcium ion concentration (GO:0051481)2.65106737
71regulation of synaptic plasticity (GO:0048167)2.63672684
72cytoskeletal anchoring at plasma membrane (GO:0007016)2.60112286
73regulation of synaptic transmission, glutamatergic (GO:0051966)2.59622625
74synaptic vesicle endocytosis (GO:0048488)2.59339650
75regulation of dendritic spine development (GO:0060998)2.58347068
76regulation of vesicle fusion (GO:0031338)2.56740820
77negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.56663938
78neurotransmitter transport (GO:0006836)2.56344274
79detection of calcium ion (GO:0005513)2.56178219
80innervation (GO:0060384)2.55860102
81positive regulation of potassium ion transmembrane transport (GO:1901381)2.54808736
82membrane depolarization (GO:0051899)2.54526432
83postsynaptic membrane organization (GO:0001941)2.54392271
84G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.54285532
85neuronal ion channel clustering (GO:0045161)2.53883331
86negative regulation of cell size (GO:0045792)2.53710255
87membrane repolarization (GO:0086009)2.53326930
88positive regulation of synaptic transmission, GABAergic (GO:0032230)2.53325228
89nerve growth factor signaling pathway (GO:0038180)2.52630115
90positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.52165722
91synapse organization (GO:0050808)2.52004163
92positive regulation of dendritic spine morphogenesis (GO:0061003)2.51529387
93regulation of membrane repolarization (GO:0060306)2.51482210
94positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.51179206
95suckling behavior (GO:0001967)2.50625594
96transmission of nerve impulse (GO:0019226)2.49733903
97regulation of neurotransmitter secretion (GO:0046928)2.48536587
98membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.48000692
99regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.47677570
100potassium ion homeostasis (GO:0055075)2.47315010
101regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.47236691
102regulation of cell communication by electrical coupling (GO:0010649)2.45105658
103regulation of cAMP-dependent protein kinase activity (GO:2000479)2.44409037
104cell migration in hindbrain (GO:0021535)2.44244491
105gamma-aminobutyric acid signaling pathway (GO:0007214)2.44088301
106organelle transport along microtubule (GO:0072384)2.43573276
107negative regulation of dendrite morphogenesis (GO:0050774)2.42760060
108response to parathyroid hormone (GO:0071107)2.32945772
109regulation of clathrin-mediated endocytosis (GO:2000369)2.32202853
110apical protein localization (GO:0045176)2.30144517
111negative regulation of neurotransmitter secretion (GO:0046929)2.28992145
112astrocyte development (GO:0014002)2.27308911
113cardiac myofibril assembly (GO:0055003)2.26301672
114Golgi to plasma membrane protein transport (GO:0043001)2.26234848
115presynaptic membrane assembly (GO:0097105)2.25450279
116cellular response to catecholamine stimulus (GO:0071870)2.25446468
117cellular response to monoamine stimulus (GO:0071868)2.25446468
118regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.25324144
119positive regulation of nitric-oxide synthase activity (GO:0051000)2.24404305
120cellular sodium ion homeostasis (GO:0006883)2.23395360
121endocardial cushion development (GO:0003197)2.20253849
122positive regulation of glucose import (GO:0046326)2.19522967
123peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.18552012
124presynaptic membrane organization (GO:0097090)2.18074381
125Golgi to plasma membrane transport (GO:0006893)2.17724950
126positive regulation of calcium ion transmembrane transporter activity (GO:1901021)2.16736294
127regulation of cardiac muscle cell contraction (GO:0086004)2.15711084
128regulation of actin filament-based movement (GO:1903115)2.15568844
129membrane assembly (GO:0071709)2.15478035
130positive regulation of dendritic spine development (GO:0060999)2.14879756
131regulation of axon extension involved in axon guidance (GO:0048841)2.14710183
132response to monoamine (GO:0071867)2.12057056
133response to catecholamine (GO:0071869)2.12057056
134actomyosin structure organization (GO:0031032)2.11125943
135insulin-like growth factor receptor signaling pathway (GO:0048009)2.10834660
136neuromuscular junction development (GO:0007528)2.10079177
137positive regulation of dendrite development (GO:1900006)2.09910569
138cerebellar Purkinje cell layer development (GO:0021680)2.09345854
139positive regulation of glucose transport (GO:0010828)2.08265171
140embryonic camera-type eye morphogenesis (GO:0048596)2.06744634
141cardiac muscle contraction (GO:0060048)2.04789797
142regulation of skeletal muscle cell differentiation (GO:2001014)2.00332917
143myoblast fusion (GO:0007520)1.99360663
144skin morphogenesis (GO:0043589)1.98413057
145regulation of calcineurin-NFAT signaling cascade (GO:0070884)1.97978094
146astrocyte differentiation (GO:0048708)1.97698833
147carnitine shuttle (GO:0006853)1.96950615
148positive regulation of actin filament depolymerization (GO:0030836)1.96456926

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.96959022
2SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.78367502
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.70233461
4GBX2_23144817_ChIP-Seq_PC3_Human2.65139055
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.63872494
6RNF2_18974828_ChIP-Seq_MESCs_Mouse2.58528076
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.58528076
8DROSHA_22980978_ChIP-Seq_HELA_Human2.45987734
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.34325917
10SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.34041357
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.33446144
12* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.32258106
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.26097952
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.25164785
15* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.21241461
16* RARB_27405468_Chip-Seq_BRAIN_Mouse2.17203109
17EED_16625203_ChIP-ChIP_MESCs_Mouse2.10532751
18EZH2_27294783_Chip-Seq_ESCs_Mouse2.08172128
19SUZ12_27294783_Chip-Seq_ESCs_Mouse2.04223831
20RNF2_27304074_Chip-Seq_ESCs_Mouse2.02713905
21* REST_21632747_ChIP-Seq_MESCs_Mouse1.94085812
22ESR2_21235772_ChIP-Seq_MCF-7_Human1.83688789
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.79435565
24AR_21572438_ChIP-Seq_LNCaP_Human1.78999684
25EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.73918461
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.66523994
27MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.64558661
28ESR1_21235772_ChIP-Seq_MCF-7_Human1.64164570
29IKZF1_21737484_ChIP-ChIP_HCT116_Human1.60443721
30REST_18959480_ChIP-ChIP_MESCs_Mouse1.60052227
31TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.55849691
32WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.48733423
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.45173855
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.42295946
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.42177919
36WT1_25993318_ChIP-Seq_PODOCYTE_Human1.39650078
37* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.39558410
38NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.39248906
39NRF2_20460467_ChIP-Seq_MEFs_Mouse1.39248906
40SMAD4_21799915_ChIP-Seq_A2780_Human1.38266637
41ZNF274_21170338_ChIP-Seq_K562_Hela1.36949067
42TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.34754386
43RING1B_27294783_Chip-Seq_ESCs_Mouse1.34709075
44RBPJ_22232070_ChIP-Seq_NCS_Mouse1.34216883
45ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.34136124
46WT1_19549856_ChIP-ChIP_CCG9911_Human1.33689805
47EP300_21415370_ChIP-Seq_HL-1_Mouse1.33106421
48NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.32883830
49* KDM2B_26808549_Chip-Seq_K562_Human1.32027138
50PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.31282854
51AHR_22903824_ChIP-Seq_MCF-7_Human1.30602915
52ARNT_22903824_ChIP-Seq_MCF-7_Human1.30477527
53SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30427597
54FOXM1_26456572_ChIP-Seq_MCF-7_Human1.30325470
55CDX2_19796622_ChIP-Seq_MESCs_Mouse1.30040703
56ZFP57_27257070_Chip-Seq_ESCs_Mouse1.29758813
57NR3C1_23031785_ChIP-Seq_PC12_Mouse1.29717903
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.27899461
59* SOX2_21211035_ChIP-Seq_LN229_Gbm1.27273081
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.25900076
61CLOCK_20551151_ChIP-Seq_293T_Human1.25579341
62ERG_21242973_ChIP-ChIP_JURKAT_Human1.25100349
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23793150
64RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.23413081
65DNAJC2_21179169_ChIP-ChIP_NT2_Human1.22337007
66TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.21761121
67AR_19668381_ChIP-Seq_PC3_Human1.20747460
68TP63_17297297_ChIP-ChIP_HaCaT_Human1.19979557
69EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.19775881
70PIAS1_25552417_ChIP-Seq_VCAP_Human1.19081249
71TAF15_26573619_Chip-Seq_HEK293_Human1.17138576
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.16337658
73NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.16228984
74POU3F2_20337985_ChIP-ChIP_501MEL_Human1.15979265
75* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.15448370
76SMAD3_21741376_ChIP-Seq_EPCs_Human1.14795635
77TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.14568492
78ZFP281_18757296_ChIP-ChIP_E14_Mouse1.13084571
79VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.12763618
80TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12534432
81DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.11915960
82EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.10741283
83CBX2_27304074_Chip-Seq_ESCs_Mouse1.10280755
84CJUN_26792858_Chip-Seq_BT549_Human1.10227986
85SOX9_24532713_ChIP-Seq_HFSC_Mouse1.10189185
86NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.09830222
87AR_25329375_ChIP-Seq_VCAP_Human1.09025633
88CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08934023
89TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.07923914
90* TBX20_22328084_ChIP-Seq_HEART_Mouse1.06861090
91* TBX20_22080862_ChIP-Seq_HEART_Mouse1.06861090
92NANOG_18555785_Chip-Seq_ESCs_Mouse1.05997090
93TP53_16413492_ChIP-PET_HCT116_Human1.05302363
94* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.05224049
95SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.04412551
96OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.03868304
97PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03703700
98STAT3_23295773_ChIP-Seq_U87_Human1.03487376
99ESR1_20079471_ChIP-ChIP_T-47D_Human1.02838858
100* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.02335779
101LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01974552
102P300_19829295_ChIP-Seq_ESCs_Human1.01947717
103* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.01340311
104AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.00919617
105ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.00812125
106SMAD4_21741376_ChIP-Seq_HESCs_Human1.00343731
107* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.00295467
108SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00163533
109TOP2B_26459242_ChIP-Seq_MCF-7_Human1.00025892
110SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.99925244
111FOXA2_19822575_ChIP-Seq_HepG2_Human0.99159005
112NR3C1_21868756_ChIP-Seq_MCF10A_Human0.98785741
113GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.98174085
114FOXO3_23340844_ChIP-Seq_DLD1_Human0.97715996
115* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.95916833
116ZFP281_27345836_Chip-Seq_ESCs_Mouse0.95795123
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.95502587
118TP53_18474530_ChIP-ChIP_U2OS_Human0.94340945
119SMAD3_21741376_ChIP-Seq_HESCs_Human0.94153459
120* NFIB_24661679_ChIP-Seq_LUNG_Mouse0.94055980
121CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.93746065
122TCF4_23295773_ChIP-Seq_U87_Human0.92531630
123P53_22127205_ChIP-Seq_FIBROBLAST_Human0.92506312
124* MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91765858
125SMAD3_21741376_ChIP-Seq_ESCs_Human0.90872406
126BCAT_22108803_ChIP-Seq_LS180_Human0.90772247
127ISL1_27105846_Chip-Seq_CPCs_Mouse0.89411559
128CTNNB1_20460455_ChIP-Seq_HCT116_Human0.89255329
129* KDM2B_26808549_Chip-Seq_JURKAT_Human0.88454811
130TRIM28_21343339_ChIP-Seq_HEK293_Human0.88129800
131STAT6_21828071_ChIP-Seq_BEAS2B_Human0.85753930
132RXR_22108803_ChIP-Seq_LS180_Human0.85066355
133RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.84550367

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.70781064
2MP0003880_abnormal_central_pattern3.85868175
3MP0003635_abnormal_synaptic_transmissio3.56385979
4MP0009780_abnormal_chondrocyte_physiolo2.91756475
5MP0004270_analgesia2.91094192
6MP0002063_abnormal_learning/memory/cond2.82641785
7MP0009745_abnormal_behavioral_response2.68617427
8MP0002064_seizures2.47065459
9MP0005423_abnormal_somatic_nervous2.39752195
10MP0000751_myopathy2.35784223
11MP0008438_abnormal_cutaneous_collagen2.32678073
12MP0002572_abnormal_emotion/affect_behav2.25641216
13MP0009046_muscle_twitch2.24530017
14MP0002822_catalepsy2.20851270
15MP0002837_dystrophic_cardiac_calcinosis2.18204922
16MP0001968_abnormal_touch/_nociception2.14030739
17MP0003705_abnormal_hypodermis_morpholog2.12950316
18MP0002909_abnormal_adrenal_gland2.10212391
19MP0001958_emphysema2.08410702
20MP0001486_abnormal_startle_reflex2.05525712
21MP0002272_abnormal_nervous_system1.98939630
22MP0008569_lethality_at_weaning1.90504318
23MP0002734_abnormal_mechanical_nocicepti1.89911287
24MP0000778_abnormal_nervous_system1.88568872
25MP0005275_abnormal_skin_tensile1.77768730
26MP0005409_darkened_coat_color1.69750142
27MP0004145_abnormal_muscle_electrophysio1.68571892
28MP0002067_abnormal_sensory_capabilities1.66898775
29MP0002877_abnormal_melanocyte_morpholog1.66593208
30MP0001501_abnormal_sleep_pattern1.63875202
31MP0000569_abnormal_digit_pigmentation1.59714449
32MP0002184_abnormal_innervation1.58569586
33MP0003787_abnormal_imprinting1.58203291
34MP0004858_abnormal_nervous_system1.57599164
35MP0005503_abnormal_tendon_morphology1.55928994
36MP0004885_abnormal_endolymph1.55085621
37MP0002736_abnormal_nociception_after1.53189686
38MP0004811_abnormal_neuron_physiology1.52407157
39MP0005386_behavior/neurological_phenoty1.51325072
40MP0004924_abnormal_behavior1.51325072
41MP0001440_abnormal_grooming_behavior1.50762313
42MP0004215_abnormal_myocardial_fiber1.50241539
43MP0002735_abnormal_chemical_nociception1.48975182
44MP0002557_abnormal_social/conspecific_i1.48310410
45MP0000462_abnormal_digestive_system1.46294282
46MP0003329_amyloid_beta_deposits1.45753860
47MP0002234_abnormal_pharynx_morphology1.44238107
48MP0008961_abnormal_basal_metabolism1.43961080
49MP0003091_abnormal_cell_migration1.42242788
50MP0009384_cardiac_valve_regurgitation1.39917233
51MP0002896_abnormal_bone_mineralization1.38878063
52MP0002733_abnormal_thermal_nociception1.36325713
53MP0000013_abnormal_adipose_tissue1.35525863
54MP0001970_abnormal_pain_threshold1.34029056
55MP0000955_abnormal_spinal_cord1.33740931
56MP0003122_maternal_imprinting1.31867253
57MP0004085_abnormal_heartbeat1.31048696
58MP0010368_abnormal_lymphatic_system1.30499940
59MP0004130_abnormal_muscle_cell1.30469457
60MP0004272_abnormal_basement_membrane1.30260863
61MP0002882_abnormal_neuron_morphology1.28145747
62MP0004036_abnormal_muscle_relaxation1.27372285
63MP0001984_abnormal_olfaction1.25668415
64MP0005257_abnormal_intraocular_pressure1.24725792
65MP0010678_abnormal_skin_adnexa1.22202407
66MP0003633_abnormal_nervous_system1.21426012
67MP0003123_paternal_imprinting1.19680681
68MP0004084_abnormal_cardiac_muscle1.19233407
69MP0002066_abnormal_motor_capabilities/c1.17992867
70MP0001502_abnormal_circadian_rhythm1.17921322
71MP0003879_abnormal_hair_cell1.17438911
72MP0003137_abnormal_impulse_conducting1.16850005
73MP0000383_abnormal_hair_follicle1.15351426
74MP0005623_abnormal_meninges_morphology1.14734979
75MP0001299_abnormal_eye_distance/1.12620602
76MP0004233_abnormal_muscle_weight1.12566620
77MP0001879_abnormal_lymphatic_vessel1.09451448
78MP0005187_abnormal_penis_morphology1.08833280
79MP0003279_aneurysm1.07894217
80MP0002108_abnormal_muscle_morphology1.07155963
81MP0003868_abnormal_feces_composition1.06554026
82MP0002009_preneoplasia1.06365847
83MP0000566_synostosis1.04865085
84MP0003566_abnormal_cell_adhesion1.04069263
85MP0005248_abnormal_Harderian_gland1.04037045
86MP0002152_abnormal_brain_morphology1.03605780
87MP0000534_abnormal_ureter_morphology1.02733701
88MP0004484_altered_response_of1.02583854
89MP0003632_abnormal_nervous_system1.02108972
90MP0005620_abnormal_muscle_contractility1.00222563
91MP0005646_abnormal_pituitary_gland0.99888691
92MP0000733_abnormal_muscle_development0.99794629
93MP0003283_abnormal_digestive_organ0.99161499
94MP0005645_abnormal_hypothalamus_physiol0.96879390
95MP0006276_abnormal_autonomic_nervous0.96854270
96MP0004087_abnormal_muscle_fiber0.95993754
97MP0000762_abnormal_tongue_morphology0.93437479
98MP0003631_nervous_system_phenotype0.92259051
99MP0002127_abnormal_cardiovascular_syste0.92101465
100MP0001177_atelectasis0.91789887
101MP0000747_muscle_weakness0.91706182
102MP0010234_abnormal_vibrissa_follicle0.90963863
103MP0010352_gastrointestinal_tract_polyps0.89981535
104MP0005551_abnormal_eye_electrophysiolog0.89326791
105MP0003045_fibrosis0.87857722
106MP0000537_abnormal_urethra_morphology0.87624569
107MP0000003_abnormal_adipose_tissue0.86271116
108MP0005394_taste/olfaction_phenotype0.86090829
109MP0005499_abnormal_olfactory_system0.86090829
110MP0004510_myositis0.85584120
111MP0003942_abnormal_urinary_system0.85518232
112MP0005595_abnormal_vascular_smooth0.85112244
113MP0002069_abnormal_eating/drinking_beha0.85033917
114MP0002972_abnormal_cardiac_muscle0.84791711
115MP0006072_abnormal_retinal_apoptosis0.84610553
116MP0005375_adipose_tissue_phenotype0.83782353
117MP0003634_abnormal_glial_cell0.82143281
118MP0002971_abnormal_brown_adipose0.81403549
119MP0000428_abnormal_craniofacial_morphol0.78312779
120MP0002090_abnormal_vision0.78119010
121MP0000767_abnormal_smooth_muscle0.74751569
122MP0000749_muscle_degeneration0.73459694
123MP0008874_decreased_physiological_sensi0.72292440
124MP0000759_abnormal_skeletal_muscle0.72189994
125MP0005167_abnormal_blood-brain_barrier0.70409204
126MP0002229_neurodegeneration0.70404935
127MP0003690_abnormal_glial_cell0.70148204
128MP0005535_abnormal_body_temperature0.70061401
129MP0002106_abnormal_muscle_physiology0.69632926
130MP0003646_muscle_fatigue0.69162639
131MP0006138_congestive_heart_failure0.68993794
132MP0004043_abnormal_pH_regulation0.66622897
133MP0000631_abnormal_neuroendocrine_gland0.66231202
134MP0000920_abnormal_myelination0.66086058
135MP0001943_abnormal_respiration0.65733866
136MP0005330_cardiomyopathy0.65311658
137MP0005369_muscle_phenotype0.65055225
138MP0010386_abnormal_urinary_bladder0.63158339

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.89420012
2Myokymia (HP:0002411)4.32902047
3Focal seizures (HP:0007359)4.08349305
4Visual hallucinations (HP:0002367)3.98828658
5Action tremor (HP:0002345)3.38157429
6Epileptic encephalopathy (HP:0200134)3.33182215
7Progressive cerebellar ataxia (HP:0002073)3.21971098
8Atonic seizures (HP:0010819)3.01147115
9Vascular tortuosity (HP:0004948)2.99115620
10Absence seizures (HP:0002121)2.98133948
11Broad-based gait (HP:0002136)2.96338326
12Protrusio acetabuli (HP:0003179)2.93215183
13Depression (HP:0000716)2.88802997
14Hyporeflexia of lower limbs (HP:0002600)2.86582770
15Supranuclear gaze palsy (HP:0000605)2.77025352
16Genetic anticipation (HP:0003743)2.76020594
17Febrile seizures (HP:0002373)2.73977889
18Poor eye contact (HP:0000817)2.71956580
19Megalencephaly (HP:0001355)2.69807674
20Papillary thyroid carcinoma (HP:0002895)2.69505549
21Generalized tonic-clonic seizures (HP:0002069)2.68913553
22Sudden death (HP:0001699)2.68100104
23Dysmetric saccades (HP:0000641)2.66630022
24Exercise-induced myalgia (HP:0003738)2.66453842
25Dysdiadochokinesis (HP:0002075)2.64427255
26Impaired social interactions (HP:0000735)2.62530137
27Abnormal social behavior (HP:0012433)2.62530137
28Drooling (HP:0002307)2.61312099
29Excessive salivation (HP:0003781)2.61312099
30Dialeptic seizures (HP:0011146)2.53969023
31Prolonged QT interval (HP:0001657)2.49311170
32Bundle branch block (HP:0011710)2.47916527
33Anxiety (HP:0000739)2.46308317
34Hyperventilation (HP:0002883)2.44827625
35Ventricular fibrillation (HP:0001663)2.42323674
36Papilledema (HP:0001085)2.42256676
37Ankle clonus (HP:0011448)2.38457191
38Truncal ataxia (HP:0002078)2.38016002
39Premature rupture of membranes (HP:0001788)2.37561287
40Gaze-evoked nystagmus (HP:0000640)2.37003500
41Impaired vibration sensation in the lower limbs (HP:0002166)2.36542936
42Amblyopia (HP:0000646)2.34850152
43Dysmetria (HP:0001310)2.34160907
44Macroorchidism (HP:0000053)2.33097643
45Striae distensae (HP:0001065)2.29753009
46Asymmetry of the thorax (HP:0001555)2.29742268
47Hyperphosphatemia (HP:0002905)2.28984466
48Aortic dissection (HP:0002647)2.28766786
49Agitation (HP:0000713)2.27305616
50Atrioventricular block (HP:0001678)2.27005198
51Termporal pattern (HP:0011008)2.25625136
52Insidious onset (HP:0003587)2.25625136
53Aortic aneurysm (HP:0004942)2.25533268
54Urinary bladder sphincter dysfunction (HP:0002839)2.24744220
55Urinary urgency (HP:0000012)2.24738195
56Subaortic stenosis (HP:0001682)2.24321603
57Abnormality of the left ventricular outflow tract (HP:0011103)2.24321603
58Type 1 muscle fiber predominance (HP:0003803)2.23070654
59Atrial fibrillation (HP:0005110)2.22965748
60Primary atrial arrhythmia (HP:0001692)2.22637973
61Hemiplegia (HP:0002301)2.20435010
62Cerebral inclusion bodies (HP:0100314)2.16369681
63Heart block (HP:0012722)2.15824593
64Abnormal atrioventricular conduction (HP:0005150)2.14491977
65Syncope (HP:0001279)2.14378563
66Overgrowth (HP:0001548)2.13673500
67Right ventricular cardiomyopathy (HP:0011663)2.13339299
68Lower limb amyotrophy (HP:0007210)2.11694881
69Germ cell neoplasia (HP:0100728)2.10518092
70Scanning speech (HP:0002168)2.10265613
71Mutism (HP:0002300)2.09816935
72Abnormality of the calf musculature (HP:0001430)2.09432041
73Abnormality of calcium-phosphate metabolism (HP:0100530)2.08572109
74Postural instability (HP:0002172)2.08145768
75Testicular neoplasm (HP:0010788)2.07673024
76Intention tremor (HP:0002080)2.07295655
77Increased variability in muscle fiber diameter (HP:0003557)2.05735701
78Abnormal EKG (HP:0003115)2.05639550
79Stereotypic behavior (HP:0000733)2.05171724
80Neoplasm of the heart (HP:0100544)2.04846189
81Torticollis (HP:0000473)2.04737410
82Supraventricular tachycardia (HP:0004755)2.03765954
83Obstructive sleep apnea (HP:0002870)2.02339131
84Vertebral arch anomaly (HP:0008438)2.02292015
85Supraventricular arrhythmia (HP:0005115)2.01532926
86Calf muscle hypertrophy (HP:0008981)2.00668925
87Insomnia (HP:0100785)2.00100199
88Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.99518688
89Atrophic scars (HP:0001075)1.97440859
90Epileptiform EEG discharges (HP:0011182)1.97011250
91Neurofibrillary tangles (HP:0002185)1.95676083
92Neonatal short-limb short stature (HP:0008921)1.95662403
93Abnormality of the lower motor neuron (HP:0002366)1.95548297
94EEG with generalized epileptiform discharges (HP:0011198)1.94966367
95Fetal akinesia sequence (HP:0001989)1.94824362
96Pointed chin (HP:0000307)1.94449861
97Lower limb asymmetry (HP:0100559)1.94234906
98Exostoses (HP:0100777)1.93205365
99Hemiparesis (HP:0001269)1.92170591
100Broad metatarsal (HP:0001783)1.92068848
101Mitral stenosis (HP:0001718)1.90690600
102Akinesia (HP:0002304)1.90564327
103Buphthalmos (HP:0000557)1.90237638
104Hypoventilation (HP:0002791)1.90187408
105Muscle hypertrophy of the lower extremities (HP:0008968)1.90011468
106Failure to thrive in infancy (HP:0001531)1.88202462
107Wormian bones (HP:0002645)1.87059563
108Impaired smooth pursuit (HP:0007772)1.86030156
109Rapidly progressive (HP:0003678)1.85891700
110Abnormal eating behavior (HP:0100738)1.84968869
111Difficulty running (HP:0009046)1.82983350
112Asymmetric septal hypertrophy (HP:0001670)1.82781748
113Osteolytic defects of the hand bones (HP:0009699)1.82408927
114Osteolytic defects of the phalanges of the hand (HP:0009771)1.82408927
115Pheochromocytoma (HP:0002666)1.82361925
116Hypsarrhythmia (HP:0002521)1.82190757
117Shallow orbits (HP:0000586)1.82166563
118Absent frontal sinuses (HP:0002688)1.82030719
119Mildly elevated creatine phosphokinase (HP:0008180)1.81363620
120Male infertility (HP:0003251)1.81273256
121Fragile skin (HP:0001030)1.80478789
122Postural tremor (HP:0002174)1.80458790
123Atrioventricular canal defect (HP:0006695)1.79950982
124Cerebral aneurysm (HP:0004944)1.79645402
125Arterial tortuosity (HP:0005116)1.79607176
126Aplasia involving bones of the extremities (HP:0009825)1.78734897
127Aplasia involving bones of the upper limbs (HP:0009823)1.78734897
128Aplasia of the phalanges of the hand (HP:0009802)1.78734897
129Focal dystonia (HP:0004373)1.77924755
130Blue irides (HP:0000635)1.77771730
131Central scotoma (HP:0000603)1.77732385
132Relative macrocephaly (HP:0004482)1.77103891
133Abnormality of the corticospinal tract (HP:0002492)1.77031640
134Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.76511057
135Lower limb muscle weakness (HP:0007340)1.74662933
136Inappropriate behavior (HP:0000719)1.73592473
137Exotropia (HP:0000577)1.72995593
138Thickened helices (HP:0000391)1.72282838
139Spastic gait (HP:0002064)1.72041177
140Abnormality of salivation (HP:0100755)1.71985247
141Hyperacusis (HP:0010780)1.70670299
142Aqueductal stenosis (HP:0002410)1.70078786
143Growth hormone excess (HP:0000845)1.69830337
144Progressive inability to walk (HP:0002505)1.69554984
145Bladder diverticulum (HP:0000015)1.69356122
146Abnormality of binocular vision (HP:0011514)1.68997419
147Cubitus valgus (HP:0002967)1.68990460
148Hyperextensible skin (HP:0000974)1.68785473
149Abnormality of the ischium (HP:0003174)1.68715313
150Ventricular tachycardia (HP:0004756)1.68318279
151EMG: myopathic abnormalities (HP:0003458)1.67927893
152Abnormality of skeletal muscle fiber size (HP:0012084)1.67606767
153Turricephaly (HP:0000262)1.66411262
154Hypoglycemic seizures (HP:0002173)1.66311994
155Pulmonic stenosis (HP:0001642)1.63008118
156Thyroid carcinoma (HP:0002890)1.62139812
157Menstrual irregularities (HP:0000858)1.62046994
158Spinal rigidity (HP:0003306)1.61848824
159Increased circulating renin level (HP:0000848)1.59555483
160Osteoarthritis (HP:0002758)1.58720093
161Mitral valve prolapse (HP:0001634)1.57659820
162Aneurysm (HP:0002617)1.57642003
163Complete atrioventricular canal defect (HP:0001674)1.56999312
164Bradycardia (HP:0001662)1.56882958

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK33.44629189
2EPHA43.35142870
3MARK13.06114307
4SCYL23.01310164
5MAP3K92.80088452
6MAP3K42.47310778
7DAPK22.22316141
8PRKD32.19122302
9LATS12.16278992
10PAK61.99557766
11MINK11.93740937
12PHKG11.89016885
13PHKG21.89016885
14NTRK21.87932622
15SIK21.85917314
16KSR21.74131623
17MAP2K41.65996856
18RIPK11.64240316
19MAP2K71.61484755
20TRIB31.60269652
21CAMKK11.59424366
22TRPM71.53164651
23PIK3CA1.48040777
24DMPK1.47141908
25KSR11.46614763
26MYLK1.43076467
27CDK51.34367022
28MAPK131.34261492
29CAMK1G1.33967800
30PAK31.31801572
31NEK91.31775301
32TYRO31.31068801
33LMTK21.29406825
34TESK11.27996929
35STK381.27879881
36PRKCH1.23920387
37NTRK11.22119942
38PKN21.20509938
39PRKG21.20257012
40FGFR21.18867397
41UHMK11.16774741
42AKT31.16763766
43RET1.15735054
44MAP3K71.13984597
45MARK21.09941975
46OBSCN1.09045871
47PAK21.07133628
48PDGFRA1.06071672
49TTN1.04936987
50PTK2B1.04082838
51PTK21.02173985
52RIPK41.01022199
53STK111.00232575
54MAP3K20.99285084
55FES0.96146737
56SGK2230.96024290
57SGK4940.96024290
58NEK60.94656228
59SGK30.93055589
60WNK10.91039432
61PRPF4B0.90032983
62CAMK10.87954088
63PNCK0.87048233
64STK390.86601775
65STK38L0.86578784
66CAMK2G0.86219986
67ERBB30.85987364
68TNIK0.84889937
69SGK20.83154510
70PLK20.83035014
71DAPK10.82434629
72MET0.81713264
73CAMK2A0.80972802
74CAMKK20.79590880
75CDC42BPA0.76651638
76PDPK10.76634325
77PDK10.75221870
78CASK0.74149807
79SGK10.73955665
80PRKCG0.72992328
81RPS6KB10.72428170
82DYRK1A0.72221185
83FER0.71882558
84MAP3K130.71615984
85TAOK10.71477918
86CAMK40.69848762
87FGFR40.68835868
88CSNK1G20.68554955
89DDR20.66595616
90GRK50.66525488
91PINK10.66097708
92PRKD10.65651931
93MAP3K120.65046816
94MAP3K60.64863927
95MAPK100.64840499
96LIMK10.64462164
97CAMK2B0.64229877
98EPHB10.63699301
99ALK0.63652871
100MAPK120.63112271
101JAK10.62544619
102PRKD20.62145792
103PTK60.59734577
104ILK0.59588108
105CDK190.59299824
106CDK140.58967244
107WNK40.58446557
108CDK150.58247417
109FYN0.57819943
110CDK180.56343371
111SIK10.55738584
112RPS6KA30.54289258
113EPHA30.53985722
114INSRR0.53850352
115FGFR30.53782556
116FLT30.53488491
117HIPK20.53225821
118MTOR0.53028909
119PRKCZ0.52402258
120TIE10.51907162
121ROCK10.51798524
122RPS6KA20.51533075
123PRKCE0.51167271
124LATS20.51078914
125MAP3K10.51015745
126PDGFRB0.50951997
127CAMK2D0.50735022
128CAMK1D0.50387449
129MAP2K10.49653632
130OXSR10.49155188
131ROCK20.49076152
132RPS6KB20.48382299
133FGFR10.48102004
134ICK0.47857079
135MAPK70.45896786
136BRD40.45363859

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050332.55364586
2Circadian entrainment_Homo sapiens_hsa047132.29567852
3Long-term potentiation_Homo sapiens_hsa047202.21248382
4Olfactory transduction_Homo sapiens_hsa047402.18636067
5GABAergic synapse_Homo sapiens_hsa047272.16219514
6Synaptic vesicle cycle_Homo sapiens_hsa047212.10640695
7Glutamatergic synapse_Homo sapiens_hsa047242.09645718
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.09041245
9Morphine addiction_Homo sapiens_hsa050322.03236587
10Amphetamine addiction_Homo sapiens_hsa050311.94699192
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.84938759
12Insulin secretion_Homo sapiens_hsa049111.82690952
13Dopaminergic synapse_Homo sapiens_hsa047281.80995148
14Salivary secretion_Homo sapiens_hsa049701.78401251
15Aldosterone synthesis and secretion_Homo sapiens_hsa049251.76990424
16Gastric acid secretion_Homo sapiens_hsa049711.71870215
17Renin secretion_Homo sapiens_hsa049241.71821456
18Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.71137651
19Cholinergic synapse_Homo sapiens_hsa047251.69107810
20Oxytocin signaling pathway_Homo sapiens_hsa049211.57072748
21Vitamin B6 metabolism_Homo sapiens_hsa007501.49448902
22Cocaine addiction_Homo sapiens_hsa050301.44350604
23Long-term depression_Homo sapiens_hsa047301.41762633
24Type II diabetes mellitus_Homo sapiens_hsa049301.39974634
25Dilated cardiomyopathy_Homo sapiens_hsa054141.39008355
26Taste transduction_Homo sapiens_hsa047421.38800094
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.35733821
28Calcium signaling pathway_Homo sapiens_hsa040201.35638595
29Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.34004363
30GnRH signaling pathway_Homo sapiens_hsa049121.33193072
31Gap junction_Homo sapiens_hsa045401.26533472
32cGMP-PKG signaling pathway_Homo sapiens_hsa040221.24640007
33cAMP signaling pathway_Homo sapiens_hsa040241.23498926
34Nitrogen metabolism_Homo sapiens_hsa009101.22495993
35ECM-receptor interaction_Homo sapiens_hsa045121.22061097
36Axon guidance_Homo sapiens_hsa043601.21739673
37Estrogen signaling pathway_Homo sapiens_hsa049151.20400576
38Serotonergic synapse_Homo sapiens_hsa047261.20202007
39Glioma_Homo sapiens_hsa052141.17928036
40Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.16119040
41Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.10953197
42Dorso-ventral axis formation_Homo sapiens_hsa043201.10930802
43Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.10879066
44Melanogenesis_Homo sapiens_hsa049161.05278420
45Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.04656747
46Adherens junction_Homo sapiens_hsa045201.03010641
47Phosphatidylinositol signaling system_Homo sapiens_hsa040701.02096848
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.01755463
49Vascular smooth muscle contraction_Homo sapiens_hsa042700.99291119
50Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.99077722
51ErbB signaling pathway_Homo sapiens_hsa040120.98116224
52Cardiac muscle contraction_Homo sapiens_hsa042600.97925141
53AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.91331168
54Pancreatic secretion_Homo sapiens_hsa049720.90884748
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.88068715
56Glucagon signaling pathway_Homo sapiens_hsa049220.86178461
57Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.85819265
58Amoebiasis_Homo sapiens_hsa051460.85353411
59Protein digestion and absorption_Homo sapiens_hsa049740.83160733
60Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82530533
61Endometrial cancer_Homo sapiens_hsa052130.80514308
62Renal cell carcinoma_Homo sapiens_hsa052110.79473656
63VEGF signaling pathway_Homo sapiens_hsa043700.79389793
64Hippo signaling pathway_Homo sapiens_hsa043900.78566836
65Chronic myeloid leukemia_Homo sapiens_hsa052200.78397959
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.77859646
67Thyroid hormone synthesis_Homo sapiens_hsa049180.77092010
68Histidine metabolism_Homo sapiens_hsa003400.75716234
69MAPK signaling pathway_Homo sapiens_hsa040100.75167414
70Neurotrophin signaling pathway_Homo sapiens_hsa047220.75163026
71Choline metabolism in cancer_Homo sapiens_hsa052310.74192407
72mTOR signaling pathway_Homo sapiens_hsa041500.73272005
73Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.72675661
74Rap1 signaling pathway_Homo sapiens_hsa040150.70105739
75Prolactin signaling pathway_Homo sapiens_hsa049170.70016556
76Circadian rhythm_Homo sapiens_hsa047100.68233214
77Insulin signaling pathway_Homo sapiens_hsa049100.67628364
78Non-small cell lung cancer_Homo sapiens_hsa052230.66644699
79Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.66153476
80Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63284208
81Collecting duct acid secretion_Homo sapiens_hsa049660.62581116
82Longevity regulating pathway - mammal_Homo sapiens_hsa042110.61970083
83Focal adhesion_Homo sapiens_hsa045100.61250608
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61083555
85Ras signaling pathway_Homo sapiens_hsa040140.60045626
86Wnt signaling pathway_Homo sapiens_hsa043100.59366280
87Melanoma_Homo sapiens_hsa052180.58414414
88Phototransduction_Homo sapiens_hsa047440.58200051
89Bile secretion_Homo sapiens_hsa049760.57327290
90Leukocyte transendothelial migration_Homo sapiens_hsa046700.55882917
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.55880720
92TGF-beta signaling pathway_Homo sapiens_hsa043500.55761538
93Insulin resistance_Homo sapiens_hsa049310.54156379
94Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.52856043
95Prostate cancer_Homo sapiens_hsa052150.52822309
96Thyroid cancer_Homo sapiens_hsa052160.52169762
97Colorectal cancer_Homo sapiens_hsa052100.51741466
98Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.50679204
99Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49647801
100Endocytosis_Homo sapiens_hsa041440.49237625
101Platelet activation_Homo sapiens_hsa046110.49200476
102Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.48349225
103Vibrio cholerae infection_Homo sapiens_hsa051100.48221383
104Proteoglycans in cancer_Homo sapiens_hsa052050.48091049
105Sphingolipid signaling pathway_Homo sapiens_hsa040710.47172028
106Oocyte meiosis_Homo sapiens_hsa041140.45171997
107AMPK signaling pathway_Homo sapiens_hsa041520.45079674
108Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.43395475
109Prion diseases_Homo sapiens_hsa050200.43310130
110Hedgehog signaling pathway_Homo sapiens_hsa043400.42939524
111Inositol phosphate metabolism_Homo sapiens_hsa005620.42928896
112Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.42868747
113Butanoate metabolism_Homo sapiens_hsa006500.42189708
114Ovarian steroidogenesis_Homo sapiens_hsa049130.40915772
115Central carbon metabolism in cancer_Homo sapiens_hsa052300.40569697
116Adipocytokine signaling pathway_Homo sapiens_hsa049200.40553085
117Regulation of actin cytoskeleton_Homo sapiens_hsa048100.39507154
118Tight junction_Homo sapiens_hsa045300.39214800

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