Rank | Gene Set | Z-score |
---|---|---|
1 | cell wall macromolecule catabolic process (GO:0016998) | 6.30424129 |
2 | cell wall macromolecule metabolic process (GO:0044036) | 5.07386798 |
3 | synapsis (GO:0007129) | 4.90725566 |
4 | DNA double-strand break processing (GO:0000729) | 4.63819843 |
5 | piRNA metabolic process (GO:0034587) | 4.33431811 |
6 | CENP-A containing nucleosome assembly (GO:0034080) | 4.28964010 |
7 | chromatin remodeling at centromere (GO:0031055) | 4.19412373 |
8 | myelin assembly (GO:0032288) | 4.12255819 |
9 | histone exchange (GO:0043486) | 4.08521427 |
10 | male meiosis I (GO:0007141) | 4.07149958 |
11 | proteasome assembly (GO:0043248) | 3.99115614 |
12 | nuclear pore complex assembly (GO:0051292) | 3.99015044 |
13 | regulation of meiosis I (GO:0060631) | 3.84872926 |
14 | resolution of meiotic recombination intermediates (GO:0000712) | 3.84113202 |
15 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.82608123 |
16 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.81332365 |
17 | nuclear pore organization (GO:0006999) | 3.80020976 |
18 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.77997405 |
19 | sister chromatid cohesion (GO:0007062) | 3.75494031 |
20 | regulation of DNA endoreduplication (GO:0032875) | 3.68347066 |
21 | rRNA modification (GO:0000154) | 3.64695217 |
22 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.62761067 |
23 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.62761067 |
24 | meiosis I (GO:0007127) | 3.58836472 |
25 | mitotic sister chromatid cohesion (GO:0007064) | 3.57702065 |
26 | male meiosis (GO:0007140) | 3.54834603 |
27 | rRNA methylation (GO:0031167) | 3.53404232 |
28 | DNA replication checkpoint (GO:0000076) | 3.47927575 |
29 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.46941623 |
30 | DNA replication-independent nucleosome organization (GO:0034724) | 3.46941623 |
31 | meiotic nuclear division (GO:0007126) | 3.46567340 |
32 | DNA methylation involved in gamete generation (GO:0043046) | 3.42652034 |
33 | regulation of MHC class II biosynthetic process (GO:0045346) | 3.41402719 |
34 | ribosome assembly (GO:0042255) | 3.40693317 |
35 | protein localization to kinetochore (GO:0034501) | 3.37696656 |
36 | histone H2A acetylation (GO:0043968) | 3.37601945 |
37 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.32835332 |
38 | mitotic metaphase plate congression (GO:0007080) | 3.32745723 |
39 | centriole replication (GO:0007099) | 3.32440830 |
40 | histone mRNA metabolic process (GO:0008334) | 3.31507389 |
41 | negative regulation of meiosis (GO:0045835) | 3.30217093 |
42 | metaphase plate congression (GO:0051310) | 3.29316782 |
43 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.29042826 |
44 | microtubule anchoring (GO:0034453) | 3.27363923 |
45 | N-terminal protein amino acid acetylation (GO:0006474) | 3.26950990 |
46 | mitotic recombination (GO:0006312) | 3.21768104 |
47 | chromosome organization involved in meiosis (GO:0070192) | 3.21469501 |
48 | negative regulation of DNA recombination (GO:0045910) | 3.21282747 |
49 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.20220376 |
50 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.20220376 |
51 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.14453092 |
52 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.14439146 |
53 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.10572539 |
54 | recombinational repair (GO:0000725) | 3.09053259 |
55 | spindle checkpoint (GO:0031577) | 3.08888663 |
56 | meiotic cell cycle process (GO:1903046) | 3.08779696 |
57 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.05106652 |
58 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.04434249 |
59 | non-recombinational repair (GO:0000726) | 3.04434249 |
60 | DNA synthesis involved in DNA repair (GO:0000731) | 3.03853591 |
61 | double-strand break repair via homologous recombination (GO:0000724) | 3.03143986 |
62 | regulation of centriole replication (GO:0046599) | 3.01777619 |
63 | telomere maintenance via recombination (GO:0000722) | 3.01761260 |
64 | cullin deneddylation (GO:0010388) | 3.00196531 |
65 | histone mRNA catabolic process (GO:0071044) | 2.99838060 |
66 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.99365523 |
67 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.98990761 |
68 | replication fork processing (GO:0031297) | 2.98550400 |
69 | pore complex assembly (GO:0046931) | 2.96936840 |
70 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.94918387 |
71 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.94918387 |
72 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.94918387 |
73 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.94918387 |
74 | negative regulation of sister chromatid segregation (GO:0033046) | 2.94918387 |
75 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.94577545 |
76 | mitotic spindle checkpoint (GO:0071174) | 2.93781049 |
77 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.89228299 |
78 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.88625623 |
79 | negative regulation of chromosome segregation (GO:0051985) | 2.88465221 |
80 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.87664530 |
81 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.87664530 |
82 | regulation of sister chromatid segregation (GO:0033045) | 2.87469570 |
83 | regulation of mitotic sister chromatid separation (GO:0010965) | 2.87469570 |
84 | regulation of mitotic sister chromatid segregation (GO:0033047) | 2.87469570 |
85 | reciprocal DNA recombination (GO:0035825) | 2.87213051 |
86 | reciprocal meiotic recombination (GO:0007131) | 2.87213051 |
87 | DNA-dependent DNA replication (GO:0006261) | 2.86218463 |
88 | establishment of chromosome localization (GO:0051303) | 2.83483443 |
89 | meiotic cell cycle (GO:0051321) | 2.82213093 |
90 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 2.79513127 |
91 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 2.79513127 |
92 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 2.79513127 |
93 | regulation of chromosome segregation (GO:0051983) | 2.78501940 |
94 | mitotic nuclear envelope disassembly (GO:0007077) | 2.76702380 |
95 | mitochondrial DNA replication (GO:0006264) | 2.76215718 |
96 | DNA strand elongation (GO:0022616) | 2.76098218 |
97 | mitotic G2/M transition checkpoint (GO:0044818) | 2.75864598 |
98 | gene silencing by RNA (GO:0031047) | 2.75358055 |
99 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.74427407 |
100 | positive regulation of macrophage activation (GO:0043032) | 2.72985335 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.74727784 |
2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.69684783 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.66952689 |
4 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.65918021 |
5 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.40342934 |
6 | ELK1_19687146_ChIP-ChIP_HELA_Human | 3.16483395 |
7 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.94282624 |
8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.65824353 |
9 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.54636724 |
10 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.52481684 |
11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.49404547 |
12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.42787211 |
13 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.35403044 |
14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.34162389 |
15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.23464414 |
16 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.15210473 |
17 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.15063415 |
18 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.12265774 |
19 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.08839583 |
20 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.08520990 |
21 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.03935110 |
22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.03752496 |
23 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.00021243 |
24 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.99344018 |
25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.88792461 |
26 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.88510158 |
27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.87483913 |
28 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.87177172 |
29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.84661775 |
30 | VDR_22108803_ChIP-Seq_LS180_Human | 1.82692702 |
31 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.74641951 |
32 | FUS_26573619_Chip-Seq_HEK293_Human | 1.73046975 |
33 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.62180731 |
34 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.60063596 |
35 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.54899797 |
36 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.54782173 |
37 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.52347503 |
38 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.51781278 |
39 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.49902731 |
40 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.49060721 |
41 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.48881659 |
42 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.46307940 |
43 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.44637749 |
44 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.38013338 |
45 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.33684456 |
46 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.32819536 |
47 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.31584936 |
48 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.31548373 |
49 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.29974228 |
50 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.28793338 |
51 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.26994376 |
52 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.26427104 |
53 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.23126031 |
54 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.22958447 |
55 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.20627018 |
56 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.20627018 |
57 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.19530551 |
58 | P300_19829295_ChIP-Seq_ESCs_Human | 1.18824001 |
59 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.14262989 |
60 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.12774744 |
61 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.08725856 |
62 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.08280401 |
63 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.07871242 |
64 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.07827077 |
65 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.07146112 |
66 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.06535406 |
67 | * TP53_22573176_ChIP-Seq_HFKS_Human | 1.05205825 |
68 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.03353133 |
69 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.03051689 |
70 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.02798127 |
71 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.01553188 |
72 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.01209728 |
73 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.00310167 |
74 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.00079255 |
75 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99757431 |
76 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.98714295 |
77 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.98693785 |
78 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.98594788 |
79 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.98563637 |
80 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.96785896 |
81 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.95654530 |
82 | * TTF2_22483619_ChIP-Seq_HELA_Human | 0.95491200 |
83 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.95400696 |
84 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.93828772 |
85 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.92314796 |
86 | GATA3_26560356_Chip-Seq_TH2_Human | 0.91380487 |
87 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.90421445 |
88 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.89854418 |
89 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.89833039 |
90 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.89399548 |
91 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.89390115 |
92 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.89329333 |
93 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.87882097 |
94 | * CDX2_22108803_ChIP-Seq_LS180_Human | 0.87614951 |
95 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.87177316 |
96 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.84328870 |
97 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.83517463 |
98 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.82791875 |
99 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.82625388 |
100 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.82433233 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008877_abnormal_DNA_methylation | 5.15511286 |
2 | MP0008058_abnormal_DNA_repair | 4.28471669 |
3 | MP0010094_abnormal_chromosome_stability | 4.01051790 |
4 | MP0008057_abnormal_DNA_replication | 3.64725567 |
5 | MP0008260_abnormal_autophagy | 3.48499501 |
6 | MP0003693_abnormal_embryo_hatching | 3.07742496 |
7 | MP0003890_abnormal_embryonic-extraembry | 3.05082656 |
8 | MP0003077_abnormal_cell_cycle | 2.88477466 |
9 | MP0003718_maternal_effect | 2.82607335 |
10 | MP0008789_abnormal_olfactory_epithelium | 2.67710597 |
11 | MP0003111_abnormal_nucleus_morphology | 2.63080235 |
12 | MP0004957_abnormal_blastocyst_morpholog | 2.46181145 |
13 | MP0003786_premature_aging | 2.26385870 |
14 | MP0006292_abnormal_olfactory_placode | 2.02846570 |
15 | MP0005499_abnormal_olfactory_system | 1.98897254 |
16 | MP0005394_taste/olfaction_phenotype | 1.98897254 |
17 | MP0002102_abnormal_ear_morphology | 1.96873890 |
18 | MP0003806_abnormal_nucleotide_metabolis | 1.92500497 |
19 | MP0006035_abnormal_mitochondrial_morpho | 1.88309185 |
20 | MP0008932_abnormal_embryonic_tissue | 1.88117963 |
21 | MP0002210_abnormal_sex_determination | 1.86305454 |
22 | MP0000372_irregular_coat_pigmentation | 1.85865248 |
23 | MP0003656_abnormal_erythrocyte_physiolo | 1.84942451 |
24 | MP0003567_abnormal_fetal_cardiomyocyte | 1.84548986 |
25 | MP0000569_abnormal_digit_pigmentation | 1.81920886 |
26 | MP0001929_abnormal_gametogenesis | 1.81243316 |
27 | MP0000015_abnormal_ear_pigmentation | 1.71514785 |
28 | MP0001188_hyperpigmentation | 1.66166052 |
29 | MP0003121_genomic_imprinting | 1.63913276 |
30 | MP0008007_abnormal_cellular_replicative | 1.63122665 |
31 | MP0003221_abnormal_cardiomyocyte_apopto | 1.62627527 |
32 | MP0010234_abnormal_vibrissa_follicle | 1.62386668 |
33 | MP0001293_anophthalmia | 1.62085625 |
34 | MP0010307_abnormal_tumor_latency | 1.51051089 |
35 | MP0003787_abnormal_imprinting | 1.50832514 |
36 | MP0009697_abnormal_copulation | 1.50174161 |
37 | MP0001984_abnormal_olfaction | 1.49026773 |
38 | MP0000653_abnormal_sex_gland | 1.41692752 |
39 | MP0002095_abnormal_skin_pigmentation | 1.41330607 |
40 | MP0001145_abnormal_male_reproductive | 1.37347306 |
41 | MP0002938_white_spotting | 1.34235507 |
42 | MP0004147_increased_porphyrin_level | 1.29761161 |
43 | MP0001986_abnormal_taste_sensitivity | 1.26636349 |
44 | MP0000358_abnormal_cell_content/ | 1.18932289 |
45 | MP0001119_abnormal_female_reproductive | 1.17036160 |
46 | MP0010030_abnormal_orbit_morphology | 1.16744029 |
47 | MP0003698_abnormal_male_reproductive | 1.16664333 |
48 | MP0005174_abnormal_tail_pigmentation | 1.15651333 |
49 | MP0002233_abnormal_nose_morphology | 1.13593070 |
50 | MP0002396_abnormal_hematopoietic_system | 1.13586685 |
51 | MP0005075_abnormal_melanosome_morpholog | 1.12808696 |
52 | MP0001672_abnormal_embryogenesis/_devel | 1.08326369 |
53 | MP0005380_embryogenesis_phenotype | 1.08326369 |
54 | MP0006072_abnormal_retinal_apoptosis | 1.08022450 |
55 | MP0001730_embryonic_growth_arrest | 1.06841308 |
56 | MP0003880_abnormal_central_pattern | 1.02228552 |
57 | MP0001697_abnormal_embryo_size | 1.02202101 |
58 | MP0005395_other_phenotype | 1.02061801 |
59 | MP0000350_abnormal_cell_proliferation | 1.00678517 |
60 | MP0000647_abnormal_sebaceous_gland | 0.99713878 |
61 | MP0003724_increased_susceptibility_to | 0.98832793 |
62 | MP0010352_gastrointestinal_tract_polyps | 0.96738395 |
63 | MP0004215_abnormal_myocardial_fiber | 0.96170734 |
64 | MP0006054_spinal_hemorrhage | 0.95622643 |
65 | MP0000703_abnormal_thymus_morphology | 0.95510496 |
66 | MP0000490_abnormal_crypts_of | 0.94919179 |
67 | MP0002160_abnormal_reproductive_system | 0.91858429 |
68 | MP0001324_abnormal_eye_pigmentation | 0.91614006 |
69 | MP0000313_abnormal_cell_death | 0.88174277 |
70 | MP0005389_reproductive_system_phenotype | 0.86976290 |
71 | MP0005253_abnormal_eye_physiology | 0.86924829 |
72 | MP0004197_abnormal_fetal_growth/weight/ | 0.85242689 |
73 | MP0002088_abnormal_embryonic_growth/wei | 0.84951409 |
74 | MP0005410_abnormal_fertilization | 0.84777832 |
75 | MP0005551_abnormal_eye_electrophysiolog | 0.82249503 |
76 | MP0003984_embryonic_growth_retardation | 0.81789100 |
77 | MP0002084_abnormal_developmental_patter | 0.80194441 |
78 | MP0003195_calcinosis | 0.79988065 |
79 | MP0000631_abnormal_neuroendocrine_gland | 0.79486648 |
80 | MP0001919_abnormal_reproductive_system | 0.77952332 |
81 | MP0005367_renal/urinary_system_phenotyp | 0.77558219 |
82 | MP0000516_abnormal_urinary_system | 0.77558219 |
83 | MP0002080_prenatal_lethality | 0.75289824 |
84 | MP0002161_abnormal_fertility/fecundity | 0.75128395 |
85 | MP0003937_abnormal_limbs/digits/tail_de | 0.74685219 |
86 | MP0001727_abnormal_embryo_implantation | 0.73753967 |
87 | MP0003699_abnormal_female_reproductive | 0.72943800 |
88 | MP0000689_abnormal_spleen_morphology | 0.72324378 |
89 | MP0008995_early_reproductive_senescence | 0.71238099 |
90 | MP0005384_cellular_phenotype | 0.70883345 |
91 | MP0002019_abnormal_tumor_incidence | 0.70878208 |
92 | MP0009785_altered_susceptibility_to | 0.70110990 |
93 | MP0002085_abnormal_embryonic_tissue | 0.67750333 |
94 | MP0010678_abnormal_skin_adnexa | 0.67584376 |
95 | MP0002751_abnormal_autonomic_nervous | 0.67426362 |
96 | MP0009703_decreased_birth_body | 0.66340484 |
97 | MP0004134_abnormal_chest_morphology | 0.66295229 |
98 | MP0009764_decreased_sensitivity_to | 0.65331612 |
99 | MP0002277_abnormal_respiratory_mucosa | 0.62666851 |
100 | MP0001835_abnormal_antigen_presentation | 0.62617524 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.03895795 |
2 | Volvulus (HP:0002580) | 3.94227911 |
3 | Chromsome breakage (HP:0040012) | 3.91748869 |
4 | Abnormality of chromosome stability (HP:0003220) | 3.84610064 |
5 | Meckel diverticulum (HP:0002245) | 3.82760529 |
6 | Abnormality of the ileum (HP:0001549) | 3.73781196 |
7 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.66577592 |
8 | Abnormality of the preputium (HP:0100587) | 3.26969440 |
9 | Abnormality of the labia minora (HP:0012880) | 3.20603101 |
10 | Type II lissencephaly (HP:0007260) | 3.13714449 |
11 | Retinal dysplasia (HP:0007973) | 3.10767042 |
12 | Papillary thyroid carcinoma (HP:0002895) | 2.98133743 |
13 | Colon cancer (HP:0003003) | 2.97772672 |
14 | Duodenal stenosis (HP:0100867) | 2.94931328 |
15 | Small intestinal stenosis (HP:0012848) | 2.94931328 |
16 | Molar tooth sign on MRI (HP:0002419) | 2.89293912 |
17 | Abnormality of midbrain morphology (HP:0002418) | 2.89293912 |
18 | Abnormality of DNA repair (HP:0003254) | 2.81173107 |
19 | Pancreatic cysts (HP:0001737) | 2.78969021 |
20 | Abnormality of the duodenum (HP:0002246) | 2.65761403 |
21 | Fair hair (HP:0002286) | 2.57809550 |
22 | Exercise-induced muscle cramps (HP:0003710) | 2.57382935 |
23 | Abnormal lung lobation (HP:0002101) | 2.56718325 |
24 | Bile duct proliferation (HP:0001408) | 2.49852390 |
25 | Abnormal biliary tract physiology (HP:0012439) | 2.49852390 |
26 | Intestinal atresia (HP:0011100) | 2.43334204 |
27 | Clubbing of toes (HP:0100760) | 2.41757806 |
28 | Median cleft lip (HP:0000161) | 2.37017841 |
29 | Abnormality of the carotid arteries (HP:0005344) | 2.36529331 |
30 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.35326970 |
31 | Cerebellar dysplasia (HP:0007033) | 2.34727791 |
32 | Myelodysplasia (HP:0002863) | 2.34608401 |
33 | Sloping forehead (HP:0000340) | 2.33818512 |
34 | Bifid tongue (HP:0010297) | 2.30723211 |
35 | Embryonal renal neoplasm (HP:0011794) | 2.21611418 |
36 | Oligodactyly (hands) (HP:0001180) | 2.18500862 |
37 | Neoplasm of the adrenal cortex (HP:0100641) | 2.16347025 |
38 | Medulloblastoma (HP:0002885) | 2.13410879 |
39 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.09853143 |
40 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.09853143 |
41 | Medial flaring of the eyebrow (HP:0010747) | 2.09286005 |
42 | Short tibia (HP:0005736) | 2.06212647 |
43 | Squamous cell carcinoma (HP:0002860) | 2.05747634 |
44 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.05151655 |
45 | Congenital primary aphakia (HP:0007707) | 2.05121228 |
46 | Overlapping toe (HP:0001845) | 2.02797087 |
47 | Acute necrotizing encephalopathy (HP:0006965) | 2.01238574 |
48 | Pancreatic fibrosis (HP:0100732) | 1.99823085 |
49 | Horseshoe kidney (HP:0000085) | 1.99081382 |
50 | Astigmatism (HP:0000483) | 1.98258765 |
51 | Ectopic kidney (HP:0000086) | 1.94797741 |
52 | Lissencephaly (HP:0001339) | 1.94783509 |
53 | Rhabdomyosarcoma (HP:0002859) | 1.94464988 |
54 | Type I transferrin isoform profile (HP:0003642) | 1.92031943 |
55 | Abnormal spermatogenesis (HP:0008669) | 1.91526348 |
56 | Stomach cancer (HP:0012126) | 1.91499495 |
57 | Acute encephalopathy (HP:0006846) | 1.91029786 |
58 | Microvesicular hepatic steatosis (HP:0001414) | 1.90030017 |
59 | Thyroid carcinoma (HP:0002890) | 1.88311231 |
60 | Azoospermia (HP:0000027) | 1.86918035 |
61 | Stenosis of the external auditory canal (HP:0000402) | 1.86485972 |
62 | Poor coordination (HP:0002370) | 1.86408558 |
63 | Neoplasm of the adrenal gland (HP:0100631) | 1.85124338 |
64 | Increased nuchal translucency (HP:0010880) | 1.84796595 |
65 | Increased hepatocellular lipid droplets (HP:0006565) | 1.83764386 |
66 | Dyschromatopsia (HP:0007641) | 1.83748732 |
67 | Small hand (HP:0200055) | 1.83738417 |
68 | Nephrogenic diabetes insipidus (HP:0009806) | 1.83279918 |
69 | Degeneration of anterior horn cells (HP:0002398) | 1.83106636 |
70 | Abnormality of the anterior horn cell (HP:0006802) | 1.83106636 |
71 | Nephronophthisis (HP:0000090) | 1.82029006 |
72 | Gait imbalance (HP:0002141) | 1.81748235 |
73 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.80778387 |
74 | Abnormality of alanine metabolism (HP:0010916) | 1.80778387 |
75 | Hyperalaninemia (HP:0003348) | 1.80778387 |
76 | Genital tract atresia (HP:0001827) | 1.79292025 |
77 | Septo-optic dysplasia (HP:0100842) | 1.79202837 |
78 | Optic nerve hypoplasia (HP:0000609) | 1.76283989 |
79 | Gastrointestinal atresia (HP:0002589) | 1.75801327 |
80 | Bone marrow hypocellularity (HP:0005528) | 1.75360337 |
81 | Aganglionic megacolon (HP:0002251) | 1.74526377 |
82 | Autoamputation (HP:0001218) | 1.74094385 |
83 | Abnormality of the septum pellucidum (HP:0007375) | 1.73340423 |
84 | Absent thumb (HP:0009777) | 1.72869357 |
85 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.71530112 |
86 | Lipid accumulation in hepatocytes (HP:0006561) | 1.71273126 |
87 | Progressive macrocephaly (HP:0004481) | 1.71145139 |
88 | Amyotrophic lateral sclerosis (HP:0007354) | 1.69326711 |
89 | Absent septum pellucidum (HP:0001331) | 1.69132564 |
90 | Vaginal atresia (HP:0000148) | 1.69023858 |
91 | Dandy-Walker malformation (HP:0001305) | 1.68535907 |
92 | Tubular atrophy (HP:0000092) | 1.68520925 |
93 | Abnormality of macular pigmentation (HP:0008002) | 1.66638847 |
94 | Stomatitis (HP:0010280) | 1.66253253 |
95 | Hypoplastic labia majora (HP:0000059) | 1.66043544 |
96 | Triphalangeal thumb (HP:0001199) | 1.65797774 |
97 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.65520749 |
98 | Chronic hepatic failure (HP:0100626) | 1.65248102 |
99 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.65104435 |
100 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.64301909 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EIF2AK3 | 3.81714522 |
2 | BRSK2 | 3.43954438 |
3 | WEE1 | 2.92925408 |
4 | BUB1 | 2.72593584 |
5 | SRPK1 | 2.71660027 |
6 | TRIM28 | 2.70270483 |
7 | TSSK6 | 2.55715273 |
8 | MST4 | 2.41218333 |
9 | WNK3 | 2.29803810 |
10 | NUAK1 | 2.25096782 |
11 | BMPR1B | 2.22674090 |
12 | STK16 | 2.18573608 |
13 | ZAK | 2.02262602 |
14 | PLK4 | 1.96658228 |
15 | TTK | 1.93416649 |
16 | PLK3 | 1.92917012 |
17 | EIF2AK1 | 1.89083189 |
18 | PBK | 1.88817987 |
19 | CDC7 | 1.77537899 |
20 | MKNK2 | 1.64836162 |
21 | ACVR1B | 1.61705209 |
22 | EPHA4 | 1.59303381 |
23 | CDK19 | 1.53828193 |
24 | MAP3K4 | 1.49641723 |
25 | PLK2 | 1.47020436 |
26 | BRSK1 | 1.46204047 |
27 | PLK1 | 1.43336459 |
28 | MAP3K9 | 1.42569956 |
29 | PDK2 | 1.36466381 |
30 | MAP3K13 | 1.31444159 |
31 | FRK | 1.24524846 |
32 | TAOK3 | 1.24260462 |
33 | STK38L | 1.22769294 |
34 | MKNK1 | 1.19414840 |
35 | ATR | 1.18852320 |
36 | BCR | 1.15197404 |
37 | EIF2AK2 | 1.12397507 |
38 | ARAF | 1.11680645 |
39 | NEK1 | 1.04272349 |
40 | VRK1 | 0.98709116 |
41 | BCKDK | 0.98445750 |
42 | CDK3 | 0.96337081 |
43 | ERBB3 | 0.95225450 |
44 | CSNK1G3 | 0.94293426 |
45 | CSNK1G1 | 0.94006786 |
46 | CAMKK2 | 0.92016195 |
47 | MAP2K7 | 0.88221278 |
48 | BRD4 | 0.86891885 |
49 | CSNK1G2 | 0.86656238 |
50 | ATM | 0.85579649 |
51 | OXSR1 | 0.85472985 |
52 | BRAF | 0.83965022 |
53 | TEC | 0.83705724 |
54 | PNCK | 0.83082109 |
55 | TNIK | 0.82985406 |
56 | RAF1 | 0.81977816 |
57 | STK3 | 0.81152937 |
58 | DYRK2 | 0.71968622 |
59 | CSNK1A1L | 0.70448321 |
60 | NEK6 | 0.69834270 |
61 | FGR | 0.69523510 |
62 | CHEK1 | 0.65832571 |
63 | MAP3K5 | 0.64837652 |
64 | DYRK3 | 0.64046714 |
65 | PRKCE | 0.62116279 |
66 | AURKB | 0.61867148 |
67 | PAK3 | 0.61243981 |
68 | ERBB4 | 0.60354870 |
69 | CCNB1 | 0.59320158 |
70 | NLK | 0.58144404 |
71 | CASK | 0.53790512 |
72 | FER | 0.52137605 |
73 | TXK | 0.51299408 |
74 | MAP4K2 | 0.51097364 |
75 | MAPK13 | 0.50236603 |
76 | CDK7 | 0.48717986 |
77 | KIT | 0.48316380 |
78 | MAP3K14 | 0.47212833 |
79 | STK4 | 0.46585849 |
80 | PIM1 | 0.44599871 |
81 | STK10 | 0.43668987 |
82 | RPS6KA4 | 0.43603497 |
83 | MELK | 0.42028793 |
84 | KSR1 | 0.41526218 |
85 | YES1 | 0.41021132 |
86 | TGFBR1 | 0.40675148 |
87 | RPS6KA5 | 0.39492973 |
88 | TNK2 | 0.37578299 |
89 | CHEK2 | 0.36784875 |
90 | MET | 0.35653271 |
91 | INSRR | 0.33060469 |
92 | MOS | 0.32910380 |
93 | CSNK2A1 | 0.31242472 |
94 | CDK1 | 0.31093463 |
95 | ADRBK2 | 0.29685306 |
96 | CSK | 0.29566509 |
97 | EGFR | 0.27643003 |
98 | LIMK1 | 0.27399910 |
99 | PRKACB | 0.26869892 |
100 | CDK2 | 0.26466451 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 3.74095712 |
2 | Homologous recombination_Homo sapiens_hsa03440 | 3.68308402 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.56381632 |
4 | Mismatch repair_Homo sapiens_hsa03430 | 3.52648621 |
5 | Basal transcription factors_Homo sapiens_hsa03022 | 3.15774357 |
6 | DNA replication_Homo sapiens_hsa03030 | 2.98633172 |
7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.90830385 |
8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.81586144 |
9 | Protein export_Homo sapiens_hsa03060 | 2.55198058 |
10 | RNA degradation_Homo sapiens_hsa03018 | 2.53138565 |
11 | RNA transport_Homo sapiens_hsa03013 | 2.47553737 |
12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.36716256 |
13 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.29843060 |
14 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.28741112 |
15 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.20740798 |
16 | Cell cycle_Homo sapiens_hsa04110 | 2.17445097 |
17 | RNA polymerase_Homo sapiens_hsa03020 | 2.07277622 |
18 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.05631549 |
19 | Spliceosome_Homo sapiens_hsa03040 | 1.84557075 |
20 | Base excision repair_Homo sapiens_hsa03410 | 1.82149193 |
21 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.74674319 |
22 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.74040027 |
23 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.60112803 |
24 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.59886815 |
25 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.58532991 |
26 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.53124044 |
27 | Parkinsons disease_Homo sapiens_hsa05012 | 1.52556825 |
28 | Huntingtons disease_Homo sapiens_hsa05016 | 1.29910866 |
29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.24579685 |
30 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.22416568 |
31 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.12589828 |
32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.08874723 |
33 | Legionellosis_Homo sapiens_hsa05134 | 1.08612367 |
34 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.02143130 |
35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.02080834 |
36 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.99511482 |
37 | Allograft rejection_Homo sapiens_hsa05330 | 0.99224578 |
38 | Asthma_Homo sapiens_hsa05310 | 0.98007603 |
39 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.97208676 |
40 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.97008775 |
41 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.96305501 |
42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.94805378 |
43 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.94509706 |
44 | Purine metabolism_Homo sapiens_hsa00230 | 0.91167789 |
45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.89692834 |
46 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.88348358 |
47 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.85968878 |
48 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.84436144 |
49 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.84366169 |
50 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.83959169 |
51 | Circadian rhythm_Homo sapiens_hsa04710 | 0.78132126 |
52 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.77666458 |
53 | Shigellosis_Homo sapiens_hsa05131 | 0.75113252 |
54 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.71587711 |
55 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.68005794 |
56 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.64438038 |
57 | Phagosome_Homo sapiens_hsa04145 | 0.63191448 |
58 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.62974304 |
59 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.58089540 |
60 | Viral myocarditis_Homo sapiens_hsa05416 | 0.55211861 |
61 | Alzheimers disease_Homo sapiens_hsa05010 | 0.54299975 |
62 | Peroxisome_Homo sapiens_hsa04146 | 0.52346479 |
63 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.49291702 |
64 | Measles_Homo sapiens_hsa05162 | 0.48340463 |
65 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.47101206 |
66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.44761765 |
67 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.42687123 |
68 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.40307862 |
69 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.39902469 |
70 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.38459530 |
71 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.37505623 |
72 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.37384373 |
73 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.37029540 |
74 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.35639423 |
75 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.34730103 |
76 | Phototransduction_Homo sapiens_hsa04744 | 0.34726987 |
77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.33881249 |
78 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.32298271 |
79 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.29707301 |
80 | Influenza A_Homo sapiens_hsa05164 | 0.28667840 |
81 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.26859803 |
82 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24771856 |
83 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.23473754 |
84 | Metabolic pathways_Homo sapiens_hsa01100 | 0.23283260 |
85 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.22415905 |
86 | Tuberculosis_Homo sapiens_hsa05152 | 0.21819037 |
87 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.19685466 |
88 | Adherens junction_Homo sapiens_hsa04520 | 0.19142843 |
89 | Taste transduction_Homo sapiens_hsa04742 | 0.16669133 |
90 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.16571982 |
91 | Apoptosis_Homo sapiens_hsa04210 | 0.15873572 |
92 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.15837502 |
93 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.15718519 |
94 | Alcoholism_Homo sapiens_hsa05034 | 0.15543692 |
95 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.14886042 |
96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.14605123 |
97 | Long-term depression_Homo sapiens_hsa04730 | 0.14351264 |
98 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.14254711 |
99 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.13697046 |
100 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.13427584 |