ZNF155

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of DNA methylation (GO:0044030)9.32169739
2regulation of female gonad development (GO:2000194)8.79544602
3piRNA metabolic process (GO:0034587)8.46645848
4regulation of acrosome reaction (GO:0060046)8.02706990
5meiotic cell cycle (GO:0051321)7.56813360
6retinal cone cell development (GO:0046549)7.34965315
7regulation of meiosis I (GO:0060631)7.11067051
8positive regulation of histone H3-K4 methylation (GO:0051571)6.30001759
9regulation of histone H3-K9 methylation (GO:0051570)6.09267127
10DNA methylation involved in gamete generation (GO:0043046)5.96288787
11multicellular organism reproduction (GO:0032504)5.94760012
12oocyte development (GO:0048599)5.84657133
13female gamete generation (GO:0007292)5.57781389
14regulation of cell maturation (GO:1903429)5.38413618
15gene silencing by RNA (GO:0031047)5.14133570
16negative regulation of reproductive process (GO:2000242)4.93916330
17centriole replication (GO:0007099)4.87934060
18negative regulation of histone methylation (GO:0031061)4.79043501
19positive regulation of humoral immune response (GO:0002922)4.75099335
20regulation of steroid hormone secretion (GO:2000831)4.67942345
21DNA replication-dependent nucleosome assembly (GO:0006335)4.51601551
22DNA replication-dependent nucleosome organization (GO:0034723)4.51601551
23protein kinase C signaling (GO:0070528)4.37249706
24positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.29861468
25positive regulation of mitotic metaphase/anaphase transition (GO:0045842)4.20939919
26positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)4.20939919
27positive regulation of mitotic sister chromatid separation (GO:1901970)4.20939919
28protein localization to kinetochore (GO:0034501)4.16275823
29glycine transport (GO:0015816)4.12225072
30protein localization to chromosome, centromeric region (GO:0071459)3.97065918
31synapsis (GO:0007129)3.91454544
32positive regulation of histone methylation (GO:0031062)3.89236269
33positive regulation of gastrulation (GO:2000543)3.86067032
34interkinetic nuclear migration (GO:0022027)3.83552047
35attachment of spindle microtubules to kinetochore (GO:0008608)3.76921010
36reproduction (GO:0000003)3.75971808
37protein localization to chromosome (GO:0034502)3.69974068
38establishment of chromosome localization (GO:0051303)3.66243814
39regulation of histone H3-K4 methylation (GO:0051569)3.60806036
40mitotic metaphase plate congression (GO:0007080)3.60110655
41regulation of spindle organization (GO:0090224)3.59501345
42mitotic chromosome condensation (GO:0007076)3.56110849
43N-terminal protein amino acid acetylation (GO:0006474)3.55387615
44regulation of meiosis (GO:0040020)3.52456801
45positive regulation of reproductive process (GO:2000243)3.48870827
46translesion synthesis (GO:0019985)3.48108958
47primitive streak formation (GO:0090009)3.47697963
48male meiosis (GO:0007140)3.43791433
49binding of sperm to zona pellucida (GO:0007339)3.40886518
50fertilization (GO:0009566)3.40177661
51positive regulation of chromosome segregation (GO:0051984)3.36238707
52regulation of chromatin silencing (GO:0031935)3.34671750
53gene silencing (GO:0016458)3.34156100
54metaphase plate congression (GO:0051310)3.33028272
55centriole assembly (GO:0098534)3.25743572
56regulation of steroid hormone biosynthetic process (GO:0090030)3.24720728
57DNA alkylation (GO:0006305)3.22093705
58DNA methylation (GO:0006306)3.22093705
59cullin deneddylation (GO:0010388)3.21715874
60nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)3.20348575
61CENP-A containing nucleosome assembly (GO:0034080)3.17368486
62phosphorelay signal transduction system (GO:0000160)3.16958936
63neuron fate determination (GO:0048664)3.16954722
64somite rostral/caudal axis specification (GO:0032525)3.16446011
65protein deneddylation (GO:0000338)3.15381439
66stress granule assembly (GO:0034063)3.13941823
67regulation of histone methylation (GO:0031060)3.13705225
68negative regulation of execution phase of apoptosis (GO:1900118)3.13583403
69oogenesis (GO:0048477)3.10239410
70aggressive behavior (GO:0002118)3.09674961
71single fertilization (GO:0007338)3.07455644
72regulation of calcium ion-dependent exocytosis (GO:0017158)3.04618373
73L-amino acid import (GO:0043092)3.02504846
74regulation of reproductive process (GO:2000241)2.98570835
75postreplication repair (GO:0006301)2.97733112
76positive regulation of uterine smooth muscle contraction (GO:0070474)2.95916847
77regulation of meiotic cell cycle (GO:0051445)2.95790978
78base-excision repair, AP site formation (GO:0006285)2.95699600
79negative regulation of histone modification (GO:0031057)2.95509609
80RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.95338300
81hyperosmotic salinity response (GO:0042538)2.91310730
82chromatin remodeling at centromere (GO:0031055)2.90716284
83male meiosis I (GO:0007141)2.90331569
84chromosome organization involved in meiosis (GO:0070192)2.87603030
85pyrimidine dimer repair (GO:0006290)2.87523311
86synaptonemal complex assembly (GO:0007130)2.83513863
87meiotic cell cycle process (GO:1903046)2.77900936
88meiotic nuclear division (GO:0007126)2.77760020
89DNA replication-independent nucleosome organization (GO:0034724)2.77322302
90DNA replication-independent nucleosome assembly (GO:0006336)2.77322302
91mitotic G2/M transition checkpoint (GO:0044818)2.76757820
92androgen receptor signaling pathway (GO:0030521)2.75656684
93sister chromatid cohesion (GO:0007062)2.71853576
94sperm-egg recognition (GO:0035036)2.69380299
95regulation of spindle checkpoint (GO:0090231)2.68264314
96regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.67784767
97epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.64887187
98negative regulation of chromatin modification (GO:1903309)2.64841230
99positive regulation of meiosis (GO:0045836)2.64717274
100histone exchange (GO:0043486)2.64637611

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.28841705
2BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.20359668
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.45204269
4HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.93153624
5GBX2_23144817_ChIP-Seq_PC3_Human2.90570989
6NOTCH1_21737748_ChIP-Seq_TLL_Human2.68067380
7SALL1_21062744_ChIP-ChIP_HESCs_Human2.55771616
8PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.32834991
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.17854460
10ZNF274_21170338_ChIP-Seq_K562_Hela2.17237699
11STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.13563870
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.07729640
13E2F7_22180533_ChIP-Seq_HELA_Human2.01468302
14EZH2_22144423_ChIP-Seq_EOC_Human10.2374134
15KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.97288805
16KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.97288805
17KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.97288805
18PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.87551471
19POU3F2_20337985_ChIP-ChIP_501MEL_Human1.84511156
20E2F4_17652178_ChIP-ChIP_JURKAT_Human1.81532295
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.78603365
22TP63_19390658_ChIP-ChIP_HaCaT_Human1.78288428
23EST1_17652178_ChIP-ChIP_JURKAT_Human1.70683535
24VDR_22108803_ChIP-Seq_LS180_Human1.70249596
25SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59864741
26HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.58601073
27UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.56560658
28WT1_19549856_ChIP-ChIP_CCG9911_Human1.52879074
29FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.52056974
30IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.47685794
31CBP_20019798_ChIP-Seq_JUKART_Human1.47685794
32P300_19829295_ChIP-Seq_ESCs_Human1.45612005
33EWS_26573619_Chip-Seq_HEK293_Human1.45284368
34GABP_17652178_ChIP-ChIP_JURKAT_Human1.42231944
35PADI4_21655091_ChIP-ChIP_MCF-7_Human1.40308010
36AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.37890976
37MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.36924466
38SMAD4_21799915_ChIP-Seq_A2780_Human1.36244171
39TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34710661
40KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.33538738
41FOXP3_21729870_ChIP-Seq_TREG_Human1.33265873
42IRF1_19129219_ChIP-ChIP_H3396_Human1.33258141
43ZFP57_27257070_Chip-Seq_ESCs_Mouse1.32018046
44VDR_23849224_ChIP-Seq_CD4+_Human1.31520714
45TCF4_23295773_ChIP-Seq_U87_Human1.31120421
46SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31059054
47* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.28364248
48* CREB1_15753290_ChIP-ChIP_HEK293T_Human1.28084300
49CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.26598490
50AR_25329375_ChIP-Seq_VCAP_Human1.24990622
51FUS_26573619_Chip-Seq_HEK293_Human1.24951589
52STAT3_23295773_ChIP-Seq_U87_Human1.22434645
53MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21130688
54CTBP2_25329375_ChIP-Seq_LNCAP_Human1.19257260
55TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.18982996
56FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.18539764
57PRDM14_20953172_ChIP-Seq_ESCs_Human1.18249162
58ELK1_19687146_ChIP-ChIP_HELA_Human1.16822507
59SMAD_19615063_ChIP-ChIP_OVARY_Human1.15865362
60PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.13872812
61RUNX2_22187159_ChIP-Seq_PCA_Human1.12606211
62CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11757166
63FLI1_27457419_Chip-Seq_LIVER_Mouse1.11534846
64EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.11407349
65FOXM1_23109430_ChIP-Seq_U2OS_Human1.11224421
66ER_23166858_ChIP-Seq_MCF-7_Human1.09611699
67* NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.08257887
68OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.07868956
69CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.07717687
70MYC_18940864_ChIP-ChIP_HL60_Human1.07318230
71SALL4_22934838_ChIP-ChIP_CD34+_Human1.06701904
72SMAD4_21741376_ChIP-Seq_EPCs_Human1.05038282
73PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.00476510
74CTBP1_25329375_ChIP-Seq_LNCAP_Human0.98903513
75* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98653154
76SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.97442529
77TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97185798
78LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96530427
79POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.95633519
80TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95633519
81SMAD3_21741376_ChIP-Seq_EPCs_Human0.93028572
82EZH2_27294783_Chip-Seq_NPCs_Mouse0.92276724
83FOXM1_26456572_ChIP-Seq_MCF-7_Human0.91960448
84MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.91764202
85TFEB_21752829_ChIP-Seq_HELA_Human0.89171188
86SMRT_27268052_Chip-Seq_Bcells_Human0.88444134
87TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87502853
88TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.86704209
89HTT_18923047_ChIP-ChIP_STHdh_Human0.86372460
90SOX2_19829295_ChIP-Seq_ESCs_Human0.86266311
91NANOG_19829295_ChIP-Seq_ESCs_Human0.86266311
92TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.86183892
93CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.84097849
94AR_21909140_ChIP-Seq_LNCAP_Human0.83196327
95FOXA1_21572438_ChIP-Seq_LNCaP_Human0.82564033
96TAL1_26923725_Chip-Seq_HPCs_Mouse0.82127532
97RNF2_27304074_Chip-Seq_NSC_Mouse0.80927535
98* NANOG_20526341_ChIP-Seq_ESCs_Human0.80781024
99TP53_22573176_ChIP-Seq_HFKS_Human0.80542535
100PCGF2_27294783_Chip-Seq_ESCs_Mouse0.80339503

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003718_maternal_effect8.21520341
2MP0006292_abnormal_olfactory_placode4.78143844
3MP0008877_abnormal_DNA_methylation4.52781671
4MP0008789_abnormal_olfactory_epithelium4.06377572
5MP0008057_abnormal_DNA_replication3.68816173
6MP0005394_taste/olfaction_phenotype3.55286668
7MP0005499_abnormal_olfactory_system3.55286668
8MP0005395_other_phenotype3.48051491
9MP0008058_abnormal_DNA_repair2.99370825
10MP0003890_abnormal_embryonic-extraembry2.61667683
11MP0003880_abnormal_central_pattern2.58478074
12MP0003693_abnormal_embryo_hatching2.52182428
13MP0002138_abnormal_hepatobiliary_system2.45511795
14MP0003699_abnormal_female_reproductive2.30312857
15MP0002139_abnormal_hepatobiliary_system2.20306757
16MP0001929_abnormal_gametogenesis2.16873033
17MP0003077_abnormal_cell_cycle2.15677060
18MP0002234_abnormal_pharynx_morphology2.10753391
19MP0002210_abnormal_sex_determination1.97990990
20MP0010094_abnormal_chromosome_stability1.93788423
21MP0010307_abnormal_tumor_latency1.80808924
22MP0003252_abnormal_bile_duct1.70609123
23MP0002751_abnormal_autonomic_nervous1.68571000
24MP0000653_abnormal_sex_gland1.68260704
25MP0002102_abnormal_ear_morphology1.68011440
26MP0005646_abnormal_pituitary_gland1.59869478
27MP0000631_abnormal_neuroendocrine_gland1.59642273
28MP0003111_abnormal_nucleus_morphology1.56743288
29MP0002233_abnormal_nose_morphology1.53663127
30MP0001119_abnormal_female_reproductive1.49572908
31MP0002161_abnormal_fertility/fecundity1.45402127
32MP0008932_abnormal_embryonic_tissue1.43679101
33MP0003183_abnormal_peptide_metabolism1.38411276
34MP0001984_abnormal_olfaction1.35320061
35MP0001145_abnormal_male_reproductive1.34370258
36MP0003121_genomic_imprinting1.31531247
37MP0001293_anophthalmia1.28048095
38MP0010234_abnormal_vibrissa_follicle1.24569973
39MP0000762_abnormal_tongue_morphology1.17148970
40MP0010030_abnormal_orbit_morphology1.13283023
41MP0005075_abnormal_melanosome_morpholog1.10759005
42MP0002928_abnormal_bile_duct1.07344008
43MP0005410_abnormal_fertilization1.06782746
44MP0003698_abnormal_male_reproductive1.05823173
45MP0002396_abnormal_hematopoietic_system1.02045795
46MP0005423_abnormal_somatic_nervous1.01611187
47MP0001730_embryonic_growth_arrest1.00411080
48MP0003950_abnormal_plasma_membrane0.99661357
49MP0003119_abnormal_digestive_system0.99331078
50MP0002160_abnormal_reproductive_system0.97773843
51MP0000566_synostosis0.95722075
52MP0000427_abnormal_hair_cycle0.90443685
53MP0005360_urolithiasis0.89988938
54MP0003656_abnormal_erythrocyte_physiolo0.89667346
55MP0005085_abnormal_gallbladder_physiolo0.86206669
56MP0009840_abnormal_foam_cell0.85922861
57MP0004142_abnormal_muscle_tone0.83792932
58MP0005380_embryogenesis_phenotype0.83448007
59MP0001672_abnormal_embryogenesis/_devel0.83448007
60MP0005551_abnormal_eye_electrophysiolog0.81184370
61MP0001324_abnormal_eye_pigmentation0.80945955
62MP0005647_abnormal_sex_gland0.80797240
63MP0008995_early_reproductive_senescence0.78220255
64MP0006276_abnormal_autonomic_nervous0.76671750
65MP0005389_reproductive_system_phenotype0.74405416
66MP0000350_abnormal_cell_proliferation0.73930698
67MP0003879_abnormal_hair_cell0.72122495
68MP0000613_abnormal_salivary_gland0.70880827
69MP0003755_abnormal_palate_morphology0.69660143
70MP0002090_abnormal_vision0.68599190
71MP0003935_abnormal_craniofacial_develop0.67471732
72MP0005253_abnormal_eye_physiology0.64504491
73MP0000049_abnormal_middle_ear0.64386763
74MP0000569_abnormal_digit_pigmentation0.63136818
75MP0000647_abnormal_sebaceous_gland0.60731863
76MP0000516_abnormal_urinary_system0.59992442
77MP0005367_renal/urinary_system_phenotyp0.59992442
78MP0001986_abnormal_taste_sensitivity0.59914349
79MP0004043_abnormal_pH_regulation0.59700413
80MP0006072_abnormal_retinal_apoptosis0.57876332
81MP0002095_abnormal_skin_pigmentation0.57197932
82MP0010678_abnormal_skin_adnexa0.57109383
83MP0005174_abnormal_tail_pigmentation0.56295529
84MP0002019_abnormal_tumor_incidence0.53904942
85MP0003221_abnormal_cardiomyocyte_apopto0.53821907
86MP0003786_premature_aging0.52373020
87MP0006035_abnormal_mitochondrial_morpho0.50598175
88MP0000377_abnormal_hair_follicle0.50270454
89MP0001664_abnormal_digestion0.49566497
90MP0002084_abnormal_developmental_patter0.49303763
91MP0006054_spinal_hemorrhage0.48890102
92MP0001188_hyperpigmentation0.48517838
93MP0001529_abnormal_vocalization0.47869383
94MP0002127_abnormal_cardiovascular_syste0.45967355
95MP0000465_gastrointestinal_hemorrhage0.45755696
96MP0005187_abnormal_penis_morphology0.43785394
97MP0000313_abnormal_cell_death0.42131289
98MP0010368_abnormal_lymphatic_system0.41131613
99MP0002272_abnormal_nervous_system0.40345133
100MP0004957_abnormal_blastocyst_morpholog0.40295700

Predicted human phenotypes

RankGene SetZ-score
1Supernumerary spleens (HP:0009799)4.83863962
2Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)4.43758477
3Papillary thyroid carcinoma (HP:0002895)4.32660037
4Anterior segment dysgenesis (HP:0007700)4.30969755
5Facial hemangioma (HP:0000329)3.99922258
6Median cleft lip (HP:0000161)3.92616868
7Oligodactyly (hands) (HP:0001180)3.74035704
8Abnormality of abdominal situs (HP:0011620)3.70041665
9Abdominal situs inversus (HP:0003363)3.70041665
10Aplasia/Hypoplasia of the fovea (HP:0008060)3.66972308
11Hypoplasia of the fovea (HP:0007750)3.66972308
12Lip pit (HP:0100267)3.60894159
13Apathy (HP:0000741)3.56345261
14Abnormal gallbladder physiology (HP:0012438)3.54247114
15Cholecystitis (HP:0001082)3.54247114
16Septo-optic dysplasia (HP:0100842)3.47822385
17Abnormality of the fovea (HP:0000493)3.46204554
18Diminished motivation (HP:0000745)3.36668357
19Impulsivity (HP:0100710)3.31785603
20Short tibia (HP:0005736)3.20625549
21Osteomalacia (HP:0002749)3.19984108
22Chromsome breakage (HP:0040012)3.03065769
23Aplasia/Hypoplasia of the tibia (HP:0005772)2.95854105
24Abnormality of the labia minora (HP:0012880)2.95023112
25Gonadotropin excess (HP:0000837)2.94228255
26Male infertility (HP:0003251)2.94004377
27Abnormal biliary tract physiology (HP:0012439)2.88671859
28Bile duct proliferation (HP:0001408)2.88671859
29Chromosomal breakage induced by crosslinking agents (HP:0003221)2.82541204
30Thyroid carcinoma (HP:0002890)2.79810944
31Capillary hemangiomas (HP:0005306)2.78215655
32Hypophosphatemic rickets (HP:0004912)2.75040933
33Abnormality of midbrain morphology (HP:0002418)2.72675609
34Molar tooth sign on MRI (HP:0002419)2.72675609
35Azoospermia (HP:0000027)2.72480579
36Hyperventilation (HP:0002883)2.70207939
37Medial flaring of the eyebrow (HP:0010747)2.69695560
38Oligodactyly (HP:0012165)2.63711026
39Dysdiadochokinesis (HP:0002075)2.62932823
40Renal cortical cysts (HP:0000803)2.62388968
41Absent septum pellucidum (HP:0001331)2.58444454
42Premature ovarian failure (HP:0008209)2.52066782
43Congenital primary aphakia (HP:0007707)2.50380641
44Lower limb hyperreflexia (HP:0002395)2.48649583
45Hypokinesia (HP:0002375)2.48371861
46Infertility (HP:0000789)2.48265305
47Bifid tongue (HP:0010297)2.46985146
48Posterior subcapsular cataract (HP:0007787)2.41099089
49Gait imbalance (HP:0002141)2.40434659
50Nephrogenic diabetes insipidus (HP:0009806)2.39044890
51Aplasia/Hypoplasia of the tongue (HP:0010295)2.36305742
52Abnormality of the septum pellucidum (HP:0007375)2.35922632
53Metaphyseal irregularity (HP:0003025)2.33917584
54Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.31976904
55Anhidrosis (HP:0000970)2.26504647
56Abnormality of the hip-girdle musculature (HP:0001445)2.25657051
57Abnormality of the musculature of the pelvis (HP:0001469)2.25657051
58Congenital sensorineural hearing impairment (HP:0008527)2.24829492
59Progressive inability to walk (HP:0002505)2.23691136
60Tubulointerstitial nephritis (HP:0001970)2.22251411
61Generalized aminoaciduria (HP:0002909)2.20688884
62Long nose (HP:0003189)2.18050475
63Conical tooth (HP:0000698)2.14483327
64Abnormal spermatogenesis (HP:0008669)2.13192728
65Genital tract atresia (HP:0001827)2.12753466
66Mutism (HP:0002300)2.12104304
67Truncal obesity (HP:0001956)2.06909921
68Urethral obstruction (HP:0000796)2.04494604
69Proximal tubulopathy (HP:0000114)2.03933403
70Pancreatic cysts (HP:0001737)2.03879887
71Nausea (HP:0002018)2.02227417
72Hypergonadotropic hypogonadism (HP:0000815)2.02162346
73Heterotopia (HP:0002282)1.98205068
74Loss of speech (HP:0002371)1.97240078
75Abnormality of chromosome stability (HP:0003220)1.96199758
76Methylmalonic acidemia (HP:0002912)1.95894277
77Medulloblastoma (HP:0002885)1.95343187
78Malnutrition (HP:0004395)1.95003588
79Striae distensae (HP:0001065)1.94072925
80Aplasia/Hypoplasia of the macula (HP:0008059)1.93409078
81Abnormality of the anterior chamber (HP:0000593)1.92584680
82Abnormality of the renal cortex (HP:0011035)1.92406531
83Rhabdomyosarcoma (HP:0002859)1.90084486
84Abnormality of chromosome segregation (HP:0002916)1.88555956
85Postaxial hand polydactyly (HP:0001162)1.86881642
86Broad-based gait (HP:0002136)1.80913584
87Volvulus (HP:0002580)1.80141175
88Neoplasm of the oral cavity (HP:0100649)1.80031871
89Gaze-evoked nystagmus (HP:0000640)1.79476589
90Sensory axonal neuropathy (HP:0003390)1.79347632
91Carpal bone hypoplasia (HP:0001498)1.77788270
92Abnormal lung lobation (HP:0002101)1.76859150
93Preaxial hand polydactyly (HP:0001177)1.76331195
94Abnormality of the phalanges of the hallux (HP:0010057)1.74730386
95Fair hair (HP:0002286)1.73772736
96Narrow forehead (HP:0000341)1.73423548
97Optic nerve hypoplasia (HP:0000609)1.72596627
98Aplasia/Hypoplasia affecting the retina (HP:0008061)1.70802963
99Complete atrioventricular canal defect (HP:0001674)1.70622476
100Maternal diabetes (HP:0009800)1.70185085

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK34.05646203
2ARAF3.43489201
3TRIM283.40050191
4MAP3K43.11683460
5MAP3K133.11650920
6TAOK32.85397485
7NUAK12.79221873
8MAP3K92.76273408
9AKT32.73126177
10MAP2K72.58159174
11STK242.47155349
12BRAF2.39203522
13NEK62.26867184
14CDK192.11251435
15NEK92.07183652
16TTK1.98869929
17ZAK1.98673551
18TNIK1.83303372
19CDC71.77618487
20RAF11.65063689
21NTRK21.62212839
22CDK91.58613320
23SRPK11.54832258
24CDK121.54233693
25MET1.51907652
26CSNK1G31.50167556
27MOS1.48496292
28AURKA1.46850878
29CSNK1G11.41873468
30CSNK1A1L1.36291835
31PRKCI1.33471615
32MAPK131.32891785
33EIF2AK11.22803823
34PLK11.22732175
35DYRK31.21968253
36STK31.21657391
37MST41.14312675
38CSNK1G21.12538949
39PLK31.10194296
40BMPR1B1.09758530
41MAP2K41.04339354
42CCNB11.02662887
43FRK0.98932119
44STK38L0.98786099
45CDK70.97087450
46ACVR1B0.90875335
47PIM10.87730459
48PLK40.83069556
49MELK0.81310866
50TGFBR20.80218194
51MKNK20.76187023
52FLT30.75972353
53ERBB30.74208227
54DMPK0.69543284
55SIK20.67870449
56BCR0.67712266
57ATM0.66811851
58WNK30.63852643
59MAP3K50.63777245
60CSNK1D0.61915110
61TGFBR10.61236465
62CDK80.60474585
63EIF2AK20.60353035
64BRSK20.59687533
65CHEK10.58690349
66KSR10.57830493
67EPHA30.57455804
68KIT0.55067877
69ATR0.54472862
70VRK10.53714822
71CASK0.53348912
72CDK20.53161541
73RPS6KA40.51266303
74BRD40.50778168
75CDK50.48923801
76CHEK20.47864478
77NEK20.47664912
78KSR20.47107287
79PKN10.46801572
80MKNK10.46348978
81IRAK10.42894100
82PLK20.42152071
83PRKG10.40977761
84MAP3K80.39548528
85PINK10.37465515
86CDK10.37409968
87CAMK2A0.37026960
88PAK10.36603770
89EPHA40.36014403
90MARK30.35720342
91TNK20.34894046
92PBK0.34606603
93OXSR10.33363086
94CHUK0.32758466
95LATS10.32721442
96SGK20.32241089
97TIE10.31592936
98BUB10.30826452
99GRK10.30746741
100PRKACA0.26306410

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal transcription factors_Homo sapiens_hsa030225.22033108
2Cell cycle_Homo sapiens_hsa041103.61107180
3Base excision repair_Homo sapiens_hsa034103.55609284
4Mismatch repair_Homo sapiens_hsa034303.38504231
5RNA degradation_Homo sapiens_hsa030182.98726374
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.83742560
7Oocyte meiosis_Homo sapiens_hsa041142.77555863
8Ovarian steroidogenesis_Homo sapiens_hsa049132.58030262
9Caffeine metabolism_Homo sapiens_hsa002322.56850095
10Dorso-ventral axis formation_Homo sapiens_hsa043202.45008463
11Homologous recombination_Homo sapiens_hsa034402.35706062
12Progesterone-mediated oocyte maturation_Homo sapiens_hsa049142.32905289
13Nucleotide excision repair_Homo sapiens_hsa034202.29087942
14Ubiquitin mediated proteolysis_Homo sapiens_hsa041202.23886988
15RNA transport_Homo sapiens_hsa030132.22313632
16Cysteine and methionine metabolism_Homo sapiens_hsa002702.16512014
17Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.15796081
18Non-homologous end-joining_Homo sapiens_hsa034502.02093025
19Fanconi anemia pathway_Homo sapiens_hsa034601.89496357
20DNA replication_Homo sapiens_hsa030301.88111073
21Circadian rhythm_Homo sapiens_hsa047101.84220443
22Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.79707616
23p53 signaling pathway_Homo sapiens_hsa041151.72118884
24Regulation of autophagy_Homo sapiens_hsa041401.66224706
25Selenocompound metabolism_Homo sapiens_hsa004501.51504184
26RNA polymerase_Homo sapiens_hsa030201.31950247
27Fatty acid elongation_Homo sapiens_hsa000621.24751998
28Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.19653227
29Steroid biosynthesis_Homo sapiens_hsa001001.11748417
30Olfactory transduction_Homo sapiens_hsa047401.11679066
31SNARE interactions in vesicular transport_Homo sapiens_hsa041301.09791197
32Herpes simplex infection_Homo sapiens_hsa051681.08093536
33Propanoate metabolism_Homo sapiens_hsa006401.07965294
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.07418845
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.06192983
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.99548274
37mRNA surveillance pathway_Homo sapiens_hsa030150.95967598
38TGF-beta signaling pathway_Homo sapiens_hsa043500.93217074
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.91927894
40ABC transporters_Homo sapiens_hsa020100.91212125
41Maturity onset diabetes of the young_Homo sapiens_hsa049500.87086787
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.87052904
43Purine metabolism_Homo sapiens_hsa002300.83609056
44Phototransduction_Homo sapiens_hsa047440.82224196
45Inositol phosphate metabolism_Homo sapiens_hsa005620.81098765
46Gap junction_Homo sapiens_hsa045400.78547275
47Protein export_Homo sapiens_hsa030600.75204689
48Spliceosome_Homo sapiens_hsa030400.74605563
49FoxO signaling pathway_Homo sapiens_hsa040680.71983403
50Thyroid cancer_Homo sapiens_hsa052160.67942965
51RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.66837663
52NOD-like receptor signaling pathway_Homo sapiens_hsa046210.66256458
53mTOR signaling pathway_Homo sapiens_hsa041500.64095567
54Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64005306
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.58298602
56Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.57995954
57Proteasome_Homo sapiens_hsa030500.51770719
58Taste transduction_Homo sapiens_hsa047420.49786170
59Phagosome_Homo sapiens_hsa041450.47967830
60Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47620286
61Collecting duct acid secretion_Homo sapiens_hsa049660.47541205
62Colorectal cancer_Homo sapiens_hsa052100.44360968
63Long-term depression_Homo sapiens_hsa047300.43094689
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.42664174
65Pyrimidine metabolism_Homo sapiens_hsa002400.41447598
66Folate biosynthesis_Homo sapiens_hsa007900.40386118
67Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.39370253
68Sphingolipid metabolism_Homo sapiens_hsa006000.38973798
69Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.38877309
70Influenza A_Homo sapiens_hsa051640.37196759
71Legionellosis_Homo sapiens_hsa051340.36822526
72Sphingolipid signaling pathway_Homo sapiens_hsa040710.35753227
73Wnt signaling pathway_Homo sapiens_hsa043100.35189197
74Serotonergic synapse_Homo sapiens_hsa047260.30612959
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.28228530
76Viral carcinogenesis_Homo sapiens_hsa052030.28204804
77GABAergic synapse_Homo sapiens_hsa047270.27203979
78Hepatitis B_Homo sapiens_hsa051610.26985677
79Nicotine addiction_Homo sapiens_hsa050330.25852494
80Ras signaling pathway_Homo sapiens_hsa040140.24608189
81Transcriptional misregulation in cancer_Homo sapiens_hsa052020.22707017
82Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.22411345
83Longevity regulating pathway - mammal_Homo sapiens_hsa042110.22212949
84Morphine addiction_Homo sapiens_hsa050320.21821589
85Hippo signaling pathway_Homo sapiens_hsa043900.19673270
86Epstein-Barr virus infection_Homo sapiens_hsa051690.19668387
87Peroxisome_Homo sapiens_hsa041460.18750910
88alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.18110210
89Ether lipid metabolism_Homo sapiens_hsa005650.18084074
90MicroRNAs in cancer_Homo sapiens_hsa052060.16457091
91Rheumatoid arthritis_Homo sapiens_hsa053230.13644013
92Jak-STAT signaling pathway_Homo sapiens_hsa046300.12482633
93HTLV-I infection_Homo sapiens_hsa051660.11585136
94Small cell lung cancer_Homo sapiens_hsa052220.10403449
95Dopaminergic synapse_Homo sapiens_hsa047280.10370192
96Shigellosis_Homo sapiens_hsa051310.10310953
97Osteoclast differentiation_Homo sapiens_hsa043800.09471311
98Butanoate metabolism_Homo sapiens_hsa006500.09213295
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.08929372
100Adherens junction_Homo sapiens_hsa045200.08643148

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