ZNF202

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.88228557
2nuclear pore organization (GO:0006999)5.06885326
3DNA unwinding involved in DNA replication (GO:0006268)4.80501890
4mitotic chromosome condensation (GO:0007076)4.59828712
5protein localization to kinetochore (GO:0034501)4.52102001
6establishment of integrated proviral latency (GO:0075713)4.43889129
7regulation of histone H3-K9 methylation (GO:0051570)4.41734643
8mitotic metaphase plate congression (GO:0007080)4.36316473
9pre-miRNA processing (GO:0031054)4.29915913
10pore complex assembly (GO:0046931)4.25968128
11protein localization to chromosome, centromeric region (GO:0071459)4.12696493
12DNA strand elongation involved in DNA replication (GO:0006271)4.12084493
13DNA strand elongation (GO:0022616)4.00040730
14mitotic sister chromatid cohesion (GO:0007064)3.91470044
15regulation of centriole replication (GO:0046599)3.83933899
16ribosome assembly (GO:0042255)3.82513000
17negative regulation of histone methylation (GO:0031061)3.81404084
18mitotic nuclear envelope disassembly (GO:0007077)3.79669834
19establishment of viral latency (GO:0019043)3.76293381
20regulation of helicase activity (GO:0051095)3.75813116
21DNA duplex unwinding (GO:0032508)3.69263573
22negative regulation of chromosome segregation (GO:0051985)3.68515073
23mitotic sister chromatid segregation (GO:0000070)3.65584470
24DNA geometric change (GO:0032392)3.63215188
25nuclear envelope disassembly (GO:0051081)3.62521383
26membrane disassembly (GO:0030397)3.62521383
27sister chromatid segregation (GO:0000819)3.62508781
28protein complex localization (GO:0031503)3.62018240
29telomere maintenance via semi-conservative replication (GO:0032201)3.61153538
30metaphase plate congression (GO:0051310)3.59616160
31negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.57226683
32negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.57226683
33negative regulation of mitotic sister chromatid segregation (GO:0033048)3.57226683
34negative regulation of mitotic sister chromatid separation (GO:2000816)3.57226683
35negative regulation of sister chromatid segregation (GO:0033046)3.57226683
36negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.56056384
37DNA topological change (GO:0006265)3.55192546
38formation of translation preinitiation complex (GO:0001731)3.52194729
39regulation of gene silencing by RNA (GO:0060966)3.49094312
40regulation of posttranscriptional gene silencing (GO:0060147)3.49094312
41regulation of gene silencing by miRNA (GO:0060964)3.49094312
42regulation of DNA methylation (GO:0044030)3.48076152
43DNA replication checkpoint (GO:0000076)3.40696963
44negative regulation of DNA repair (GO:0045738)3.40541183
45heterochromatin organization (GO:0070828)3.37787993
46CENP-A containing nucleosome assembly (GO:0034080)3.37501493
47mitotic spindle checkpoint (GO:0071174)3.34973239
48spliceosomal tri-snRNP complex assembly (GO:0000244)3.34898298
49chromatin remodeling at centromere (GO:0031055)3.33486549
50regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.32640151
51regulation of mitotic metaphase/anaphase transition (GO:0030071)3.32640151
52regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.32067668
53regulation of mitotic spindle checkpoint (GO:1903504)3.32067668
54regulation of translational fidelity (GO:0006450)3.30726747
55DNA replication initiation (GO:0006270)3.28165957
56spindle checkpoint (GO:0031577)3.28015785
57regulation of mitotic sister chromatid separation (GO:0010965)3.27413033
58regulation of mitotic sister chromatid segregation (GO:0033047)3.27413033
59regulation of sister chromatid segregation (GO:0033045)3.27413033
60ribosome biogenesis (GO:0042254)3.27378527
61mitotic spindle assembly checkpoint (GO:0007094)3.25228850
62regulation of chromosome segregation (GO:0051983)3.22665070
63positive regulation of chromosome segregation (GO:0051984)3.21378239
64spindle assembly checkpoint (GO:0071173)3.19160452
65mitotic recombination (GO:0006312)3.17766198
66regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.16998469
67cellular protein complex localization (GO:0034629)3.16783458
68DNA replication-independent nucleosome organization (GO:0034724)3.16571257
69DNA replication-independent nucleosome assembly (GO:0006336)3.16571257
70telomere maintenance via recombination (GO:0000722)3.14118648
71negative regulation of RNA splicing (GO:0033119)3.12714565
72DNA conformation change (GO:0071103)3.11200146
73regulation of spindle checkpoint (GO:0090231)3.08979774
74ATP-dependent chromatin remodeling (GO:0043044)3.08349561
75negative regulation of mRNA processing (GO:0050686)3.07887140
76establishment of chromosome localization (GO:0051303)3.07257689
77negative regulation of mRNA metabolic process (GO:1903312)3.04166668
78regulation of RNA export from nucleus (GO:0046831)3.03308445
79L-serine metabolic process (GO:0006563)2.98277146
80maturation of SSU-rRNA (GO:0030490)2.96336214
81rRNA transcription (GO:0009303)2.94422238
82viral mRNA export from host cell nucleus (GO:0046784)2.93655813
83regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.93483154
84mRNA transport (GO:0051028)2.93134308
85DNA synthesis involved in DNA repair (GO:0000731)2.91303253
86nuclear envelope organization (GO:0006998)2.91281134
87DNA ligation (GO:0006266)2.88754145
88histone exchange (GO:0043486)2.88539503
89ribonucleoprotein complex biogenesis (GO:0022613)2.86405141
90chromatin assembly or disassembly (GO:0006333)2.83476056
91DNA replication-dependent nucleosome assembly (GO:0006335)2.80876599
92DNA replication-dependent nucleosome organization (GO:0034723)2.80876599
93telomere maintenance via telomere lengthening (GO:0010833)2.80467749
94negative regulation of DNA-dependent DNA replication (GO:2000104)2.80182777
95maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.79125250
96N-terminal protein amino acid acetylation (GO:0006474)2.79077154
97chromosome condensation (GO:0030261)2.78020625
98IMP biosynthetic process (GO:0006188)2.77629270
99tRNA aminoacylation for protein translation (GO:0006418)2.76944967
100regulation of nucleobase-containing compound transport (GO:0032239)2.76924242

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.44394921
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.17672297
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.02474501
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.94576518
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.22007335
6HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.00232798
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.92451502
8MYC_19079543_ChIP-ChIP_MESCs_Mouse2.92223117
9MYC_19030024_ChIP-ChIP_MESCs_Mouse2.72177531
10KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.56053103
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.48880927
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.45391292
13KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.43593747
14KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.43593747
15KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.43593747
16MYC_18358816_ChIP-ChIP_MESCs_Mouse2.42496125
17E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.42066391
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.41617214
19MYC_22102868_ChIP-Seq_BL_Human2.40481000
20E2F1_21310950_ChIP-Seq_MCF-7_Human2.25559674
21POU5F1_18555785_ChIP-Seq_MESCs_Mouse2.23601450
22NELFA_20434984_ChIP-Seq_ESCs_Mouse2.22462845
23MYCN_18555785_ChIP-Seq_MESCs_Mouse2.19837282
24EST1_17652178_ChIP-ChIP_JURKAT_Human2.11877891
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.09586820
26MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.07839127
27AR_21909140_ChIP-Seq_LNCAP_Human2.07117438
28THAP11_20581084_ChIP-Seq_MESCs_Mouse2.06509010
29ETS1_20019798_ChIP-Seq_JURKAT_Human2.05547990
30YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.02640770
31JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.92114076
32RBPJ_22232070_ChIP-Seq_NCS_Mouse1.89897845
33DCP1A_22483619_ChIP-Seq_HELA_Human1.88131707
34ZFX_18555785_ChIP-Seq_MESCs_Mouse1.85765475
35* NOTCH1_21737748_ChIP-Seq_TLL_Human1.84482873
36FOXP3_21729870_ChIP-Seq_TREG_Human1.83497767
37XRN2_22483619_ChIP-Seq_HELA_Human1.82599304
38MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.82159651
39GABP_17652178_ChIP-ChIP_JURKAT_Human1.75880668
40PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.73242960
41TTF2_22483619_ChIP-Seq_HELA_Human1.71421044
42CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.69892046
43E2F1_18555785_ChIP-Seq_MESCs_Mouse1.64211925
44* GABP_19822575_ChIP-Seq_HepG2_Human1.58203321
45MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.56232322
46CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.54523903
47NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.51590782
48CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.51558974
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.51113703
50VDR_23849224_ChIP-Seq_CD4+_Human1.50124402
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.49585500
52CIITA_25753668_ChIP-Seq_RAJI_Human1.49053200
53DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.46660779
54STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.44502399
55TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.43987071
56ELK1_19687146_ChIP-ChIP_HELA_Human1.38163192
57NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.37588269
58PADI4_21655091_ChIP-ChIP_MCF-7_Human1.35243620
59CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.35226332
60ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.35156011
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.34923940
62KLF4_18555785_ChIP-Seq_MESCs_Mouse1.34494748
63KDM5A_27292631_Chip-Seq_BREAST_Human1.32105085
64TP63_19390658_ChIP-ChIP_HaCaT_Human1.31974468
65ELF1_17652178_ChIP-ChIP_JURKAT_Human1.30046138
66* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.27786004
67SALL1_21062744_ChIP-ChIP_HESCs_Human1.27698177
68SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.27119256
69HOXB4_20404135_ChIP-ChIP_EML_Mouse1.25801944
70PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.25589683
71SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.22142874
72ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22041184
73ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.16060467
74SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.14917950
75NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.13691361
76POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.11581282
77VDR_21846776_ChIP-Seq_THP-1_Human1.10086712
78* NANOG_16153702_ChIP-ChIP_HESCs_Human1.08553993
79YY1_21170310_ChIP-Seq_MESCs_Mouse1.05851196
80SOX2_16153702_ChIP-ChIP_HESCs_Human1.04539424
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.02003684
82TFEB_21752829_ChIP-Seq_HELA_Human1.01748080
83* CHD1_26751641_Chip-Seq_LNCaP_Human1.00758442
84TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00015331
85SOX2_18555785_ChIP-Seq_MESCs_Mouse0.99449273
86CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.98222199
87GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.97587952
88BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96796794
89NANOG_21062744_ChIP-ChIP_HESCs_Human0.96782733
90SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.96582219
91SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.95537808
92NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.95153478
93DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.90499537
94ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.88932214
95SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.88557936
96POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.87352525
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.86573582
98TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.85320211
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.85227162
100KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.84497125

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.12035675
2MP0008057_abnormal_DNA_replication4.57448643
3MP0010094_abnormal_chromosome_stability4.22503943
4MP0003111_abnormal_nucleus_morphology4.15901415
5MP0004957_abnormal_blastocyst_morpholog3.74860167
6MP0003077_abnormal_cell_cycle3.24068748
7MP0008058_abnormal_DNA_repair3.02776940
8MP0001730_embryonic_growth_arrest2.76825066
9MP0003890_abnormal_embryonic-extraembry2.67628069
10MP0003941_abnormal_skin_development2.57914643
11MP0002396_abnormal_hematopoietic_system2.57319297
12MP0008932_abnormal_embryonic_tissue2.51534622
13MP0008007_abnormal_cellular_replicative2.50850269
14MP0010307_abnormal_tumor_latency2.46921812
15MP0000350_abnormal_cell_proliferation2.37600828
16MP0010352_gastrointestinal_tract_polyps2.29363878
17MP0009672_abnormal_birth_weight2.12848905
18MP0001672_abnormal_embryogenesis/_devel2.02452201
19MP0005380_embryogenesis_phenotype2.02452201
20MP0003718_maternal_effect1.82856092
21MP0003984_embryonic_growth_retardation1.79145742
22MP0004197_abnormal_fetal_growth/weight/1.78118715
23MP0002254_reproductive_system_inflammat1.77691936
24MP0002084_abnormal_developmental_patter1.76905057
25MP0001697_abnormal_embryo_size1.75557587
26MP0002088_abnormal_embryonic_growth/wei1.72400562
27MP0002085_abnormal_embryonic_tissue1.71690747
28MP0002080_prenatal_lethality1.68806137
29MP0008877_abnormal_DNA_methylation1.60141487
30MP0000313_abnormal_cell_death1.56953609
31MP0010030_abnormal_orbit_morphology1.55805833
32MP0008260_abnormal_autophagy1.55695463
33MP0004233_abnormal_muscle_weight1.52731160
34MP0003705_abnormal_hypodermis_morpholog1.50546523
35MP0002086_abnormal_extraembryonic_tissu1.45344332
36MP0000490_abnormal_crypts_of1.42094621
37MP0006292_abnormal_olfactory_placode1.40646253
38MP0000537_abnormal_urethra_morphology1.39042006
39MP0005076_abnormal_cell_differentiation1.36415346
40MP0000428_abnormal_craniofacial_morphol1.35157701
41MP0002009_preneoplasia1.31732087
42MP0001293_anophthalmia1.23084367
43MP0002796_impaired_skin_barrier1.21780785
44MP0009703_decreased_birth_body1.21609942
45MP0002019_abnormal_tumor_incidence1.20008434
46MP0003786_premature_aging1.17822024
47MP0005451_abnormal_body_composition1.16020622
48MP0004185_abnormal_adipocyte_glucose1.14352334
49MP0000703_abnormal_thymus_morphology1.13650994
50MP0003937_abnormal_limbs/digits/tail_de1.12867248
51MP0003763_abnormal_thymus_physiology1.11213259
52MP0002697_abnormal_eye_size1.10610311
53MP0002111_abnormal_tail_morphology1.06003692
54MP0005621_abnormal_cell_physiology1.03685752
55MP0002089_abnormal_postnatal_growth/wei1.03587764
56MP0003115_abnormal_respiratory_system1.00236713
57MP0001286_abnormal_eye_development0.97697904
58MP0002233_abnormal_nose_morphology0.95509274
59MP0005501_abnormal_skin_physiology0.94053861
60MP0001915_intracranial_hemorrhage0.93387018
61MP0003123_paternal_imprinting0.92983456
62MP0001849_ear_inflammation0.92908051
63MP0005384_cellular_phenotype0.92043989
64MP0003567_abnormal_fetal_cardiomyocyte0.91078119
65MP0003861_abnormal_nervous_system0.89408644
66MP0003221_abnormal_cardiomyocyte_apopto0.89112553
67MP0003119_abnormal_digestive_system0.88075922
68MP0009278_abnormal_bone_marrow0.86740754
69MP0000432_abnormal_head_morphology0.86344297
70MP0009697_abnormal_copulation0.84064592
71MP0003453_abnormal_keratinocyte_physiol0.83165902
72MP0004808_abnormal_hematopoietic_stem0.82615371
73MP0000049_abnormal_middle_ear0.80000775
74MP0002210_abnormal_sex_determination0.79900359
75MP0002398_abnormal_bone_marrow0.79506146
76MP0003699_abnormal_female_reproductive0.74510482
77MP0003121_genomic_imprinting0.73245937
78MP0002722_abnormal_immune_system0.72576688
79MP0001145_abnormal_male_reproductive0.71787034
80MP0009053_abnormal_anal_canal0.71120365
81MP0001929_abnormal_gametogenesis0.70814253
82MP0002092_abnormal_eye_morphology0.70465292
83MP0010234_abnormal_vibrissa_follicle0.70426791
84MP0010630_abnormal_cardiac_muscle0.70201790
85MP0006035_abnormal_mitochondrial_morpho0.69103144
86MP0003935_abnormal_craniofacial_develop0.67569133
87MP0000358_abnormal_cell_content/0.67463578
88MP0005394_taste/olfaction_phenotype0.66811479
89MP0005499_abnormal_olfactory_system0.66811479
90MP0004264_abnormal_extraembryonic_tissu0.66731599
91MP0000689_abnormal_spleen_morphology0.65663503
92MP0002925_abnormal_cardiovascular_devel0.64868001
93MP0001299_abnormal_eye_distance/0.64732910
94MP0008770_decreased_survivor_rate0.64010262
95MP0003755_abnormal_palate_morphology0.63801731
96MP0003566_abnormal_cell_adhesion0.62733822
97MP0002081_perinatal_lethality0.62590067
98MP0002114_abnormal_axial_skeleton0.61388253
99MP0000653_abnormal_sex_gland0.59064567
100MP0001340_abnormal_eyelid_morphology0.59053371

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)4.14275901
2Chromsome breakage (HP:0040012)4.00610868
3Colon cancer (HP:0003003)3.80649689
4Nephroblastoma (Wilms tumor) (HP:0002667)3.48379831
5Cortical dysplasia (HP:0002539)3.42017181
6Embryonal renal neoplasm (HP:0011794)3.39329096
7Birth length less than 3rd percentile (HP:0003561)3.29937462
8Abnormality of the labia minora (HP:0012880)3.26399687
9Selective tooth agenesis (HP:0001592)3.12399090
10Abnormality of chromosome stability (HP:0003220)3.07899486
11Meckel diverticulum (HP:0002245)3.00986504
12Abnormality of the preputium (HP:0100587)2.98778728
13Microvesicular hepatic steatosis (HP:0001414)2.81135421
14Increased nuchal translucency (HP:0010880)2.80421067
15Abnormality of the ileum (HP:0001549)2.76355633
16Multiple enchondromatosis (HP:0005701)2.73666996
17Myelodysplasia (HP:0002863)2.65684203
18Abnormal hair whorl (HP:0010721)2.61244050
19Medulloblastoma (HP:0002885)2.61181394
20Abnormal lung lobation (HP:0002101)2.57331415
21Aplasia/Hypoplasia of the uvula (HP:0010293)2.52159861
22Progressive external ophthalmoplegia (HP:0000590)2.50499712
23Reticulocytopenia (HP:0001896)2.50460560
24Abnormality of DNA repair (HP:0003254)2.45133416
25Progressive muscle weakness (HP:0003323)2.41808178
26Absent radius (HP:0003974)2.35836562
27Hepatoblastoma (HP:0002884)2.26296748
28Duodenal stenosis (HP:0100867)2.25573241
29Small intestinal stenosis (HP:0012848)2.25573241
30Shoulder girdle muscle weakness (HP:0003547)2.25400674
31Poikiloderma (HP:0001029)2.25327675
32Absent forearm bone (HP:0003953)2.24776192
33Aplasia involving forearm bones (HP:0009822)2.24776192
34Neoplasm of the adrenal cortex (HP:0100641)2.22482549
35Skull defect (HP:0001362)2.16291623
36Urethral obstruction (HP:0000796)2.15108576
37High anterior hairline (HP:0009890)2.14582319
38Diastasis recti (HP:0001540)2.12811241
39Cafe-au-lait spot (HP:0000957)2.12717453
40Abnormality of the carotid arteries (HP:0005344)2.12451320
41Horseshoe kidney (HP:0000085)2.07711359
42Papillary thyroid carcinoma (HP:0002895)2.04789608
43Ectopic kidney (HP:0000086)2.03179795
44Gastrointestinal carcinoma (HP:0002672)2.01225445
45Malignant gastrointestinal tract tumors (HP:0006749)2.01225445
46Abnormality of the duodenum (HP:0002246)1.99415928
47Hyperacusis (HP:0010780)1.98945888
48Aplastic anemia (HP:0001915)1.98341182
49Abnormal number of incisors (HP:0011064)1.96752511
50Spastic diplegia (HP:0001264)1.96673111
51Capillary hemangiomas (HP:0005306)1.94762482
52Abnormality of the septum pellucidum (HP:0007375)1.93889247
53Deviation of the thumb (HP:0009603)1.93304897
54Proximal placement of thumb (HP:0009623)1.91684043
55Overriding aorta (HP:0002623)1.89753113
56Rhabdomyosarcoma (HP:0002859)1.88615218
57Squamous cell carcinoma (HP:0002860)1.88470669
58Abnormality of cells of the erythroid lineage (HP:0012130)1.88440296
59Embryonal neoplasm (HP:0002898)1.87389706
60Premature ovarian failure (HP:0008209)1.87251467
61Upper limb muscle weakness (HP:0003484)1.87004081
62Sloping forehead (HP:0000340)1.86143046
63Pelvic girdle muscle weakness (HP:0003749)1.84928266
64Intestinal fistula (HP:0100819)1.84621866
65Depressed nasal tip (HP:0000437)1.84516633
66Aplasia/Hypoplasia of the sternum (HP:0006714)1.83812346
67Deep philtrum (HP:0002002)1.83321100
68Basal cell carcinoma (HP:0002671)1.82196207
69Acute lymphatic leukemia (HP:0006721)1.81217426
70Entropion (HP:0000621)1.81026534
71Tracheoesophageal fistula (HP:0002575)1.80564302
72Acute myeloid leukemia (HP:0004808)1.80287223
73Cellular immunodeficiency (HP:0005374)1.79649268
74Rectal fistula (HP:0100590)1.79208432
75Rectovaginal fistula (HP:0000143)1.79208432
76Muscle fiber atrophy (HP:0100295)1.78973541
77Absent thumb (HP:0009777)1.78205822
78Anal stenosis (HP:0002025)1.77764249
79Generalized hypotonia (HP:0001290)1.77357896
80Broad thumb (HP:0011304)1.77082324
81Duplication of thumb phalanx (HP:0009942)1.75344962
82Choanal stenosis (HP:0000452)1.75318714
83Carpal bone hypoplasia (HP:0001498)1.74594831
84Ependymoma (HP:0002888)1.73839816
85Triphalangeal thumb (HP:0001199)1.73639660
86Vaginal fistula (HP:0004320)1.72486751
87Aplasia/Hypoplasia of the sacrum (HP:0008517)1.72338904
88Missing ribs (HP:0000921)1.71652718
89Abnormality of abdominal situs (HP:0011620)1.71349065
90Abdominal situs inversus (HP:0003363)1.71349065
91Atresia of the external auditory canal (HP:0000413)1.71286743
92Type 2 muscle fiber atrophy (HP:0003554)1.71280120
93Overlapping toe (HP:0001845)1.70365201
94Choanal atresia (HP:0000453)1.69374658
95Leiomyosarcoma (HP:0100243)1.66319623
96Uterine leiomyosarcoma (HP:0002891)1.66319623
97Neoplasm of the oral cavity (HP:0100649)1.65515248
98Neoplasm of the colon (HP:0100273)1.62188231
99Sensory axonal neuropathy (HP:0003390)1.61866283
100Thrombocytosis (HP:0001894)1.61691963

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.55720292
2MAP3K103.65176089
3BUB13.60936070
4TTK3.50006729
5MUSK3.27426641
6SRPK13.08265016
7PASK2.85467784
8CDK122.68956456
9TSSK62.44865199
10PLK42.30349725
11MKNK22.30146813
12SMG12.27929925
13BRD42.22518461
14MKNK12.21433461
15TAF12.11811043
16CDK192.03263397
17EEF2K1.89452251
18NME21.79784267
19TESK21.73964496
20EIF2AK11.65931179
21ATR1.55608144
22PLK11.49601762
23EIF2AK31.48340233
24PLK31.43025625
25PRPF4B1.40811012
26CDK71.30668183
27CHEK11.28798809
28ALK1.28091754
29CHEK21.26063759
30CDK41.16488481
31TRIB31.12329996
32VRK21.11861891
33RPS6KB21.10899759
34PIM11.07262315
35RIPK11.03021851
36BRSK21.02378081
37ATM1.01653837
38ICK1.00370921
39TIE10.98497594
40AURKB0.95028932
41MAP3K80.91259004
42STK100.89791040
43TYRO30.89334727
44CDK60.86853641
45AURKA0.83404402
46DYRK30.83290221
47WEE10.82557584
48BRSK10.82206818
49CDK20.81161949
50RAF10.80316260
51STK240.77703468
52NME10.77196998
53EIF2AK20.75606221
54MELK0.75183936
55PDGFRA0.72933293
56LATS10.72726369
57MAP3K140.70927703
58PBK0.69795321
59DMPK0.66177407
60MAP3K130.65709652
61ZAK0.65441349
62CDK10.65270517
63RPS6KA40.65047688
64CDK90.63144135
65NUAK10.62720683
66NEK20.62619664
67PAK40.61853314
68MAP3K90.61230061
69MAP2K30.56000114
70MTOR0.54595649
71FGFR20.53697908
72SCYL20.52081685
73FGFR40.51790619
74NLK0.50389873
75PIM20.49664043
76ERBB40.47970755
77STK30.46354475
78STK40.45338595
79BMX0.44370678
80FGFR10.44007622
81PRKDC0.43089012
82FES0.38841776
83FGR0.38488606
84IKBKE0.37767396
85MAP3K40.36983301
86CDK30.36820951
87CDK80.36510755
88RPS6KA10.36477524
89DYRK1B0.36258055
90CSNK1E0.35675022
91VRK10.34507127
92LATS20.32242640
93MAPK140.31079333
94TGFBR10.30526324
95CSNK2A20.29980222
96CSNK2A10.29960023
97CAMK1D0.28834825
98RPS6KC10.27849344
99RPS6KL10.27849344
100YES10.27787152

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.43034141
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.44605628
3Mismatch repair_Homo sapiens_hsa034303.42756770
4Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.32769102
5Spliceosome_Homo sapiens_hsa030403.14291308
6RNA transport_Homo sapiens_hsa030133.00732623
7Cell cycle_Homo sapiens_hsa041102.94785613
8Base excision repair_Homo sapiens_hsa034102.76550917
9Non-homologous end-joining_Homo sapiens_hsa034502.75694448
10Nucleotide excision repair_Homo sapiens_hsa034202.58653233
11mRNA surveillance pathway_Homo sapiens_hsa030152.33322302
12Basal transcription factors_Homo sapiens_hsa030222.19795115
13Fanconi anemia pathway_Homo sapiens_hsa034602.01677148
14RNA degradation_Homo sapiens_hsa030181.99735237
15Homologous recombination_Homo sapiens_hsa034401.76707405
16Ribosome_Homo sapiens_hsa030101.76702864
17Cysteine and methionine metabolism_Homo sapiens_hsa002701.54555454
18Thyroid cancer_Homo sapiens_hsa052161.43192032
19RNA polymerase_Homo sapiens_hsa030201.39090177
20Colorectal cancer_Homo sapiens_hsa052101.36043216
21Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.33696374
22Selenocompound metabolism_Homo sapiens_hsa004501.29981154
23One carbon pool by folate_Homo sapiens_hsa006701.29933074
24Chronic myeloid leukemia_Homo sapiens_hsa052201.26920631
25Acute myeloid leukemia_Homo sapiens_hsa052211.24865308
26p53 signaling pathway_Homo sapiens_hsa041151.23962480
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.21720355
28MicroRNAs in cancer_Homo sapiens_hsa052061.19591848
29Endometrial cancer_Homo sapiens_hsa052131.13934993
30Pyrimidine metabolism_Homo sapiens_hsa002401.13820973
31Central carbon metabolism in cancer_Homo sapiens_hsa052301.13434069
32Epstein-Barr virus infection_Homo sapiens_hsa051691.07755544
33Herpes simplex infection_Homo sapiens_hsa051681.06003167
34Prostate cancer_Homo sapiens_hsa052151.02322325
35Adherens junction_Homo sapiens_hsa045201.01830611
36Small cell lung cancer_Homo sapiens_hsa052221.01177264
37RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.00618902
38Lysine degradation_Homo sapiens_hsa003100.95554383
39Pancreatic cancer_Homo sapiens_hsa052120.95392646
40Biosynthesis of amino acids_Homo sapiens_hsa012300.95146840
41Viral carcinogenesis_Homo sapiens_hsa052030.94062149
42Oocyte meiosis_Homo sapiens_hsa041140.92537112
43Proteasome_Homo sapiens_hsa030500.91610397
44Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.85447965
45Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.84050256
46HTLV-I infection_Homo sapiens_hsa051660.83647261
47Non-small cell lung cancer_Homo sapiens_hsa052230.82668748
48Hepatitis B_Homo sapiens_hsa051610.72942484
49Purine metabolism_Homo sapiens_hsa002300.71546765
50Shigellosis_Homo sapiens_hsa051310.71477766
51Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.71387650
52Measles_Homo sapiens_hsa051620.70207914
53Wnt signaling pathway_Homo sapiens_hsa043100.68996304
54Bladder cancer_Homo sapiens_hsa052190.68912088
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68091102
56B cell receptor signaling pathway_Homo sapiens_hsa046620.66812831
57Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.66622495
58Apoptosis_Homo sapiens_hsa042100.65933356
59Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.65271621
60Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.65052584
61Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.62533915
62Notch signaling pathway_Homo sapiens_hsa043300.59299208
63Basal cell carcinoma_Homo sapiens_hsa052170.59271426
64Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58916242
65TGF-beta signaling pathway_Homo sapiens_hsa043500.58709535
662-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58694085
67Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58678679
68Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.55875402
69Longevity regulating pathway - mammal_Homo sapiens_hsa042110.55640904
70Renal cell carcinoma_Homo sapiens_hsa052110.54186305
71Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50657689
72Hepatitis C_Homo sapiens_hsa051600.50131295
73ErbB signaling pathway_Homo sapiens_hsa040120.50024497
74Pathways in cancer_Homo sapiens_hsa052000.49716516
75Hippo signaling pathway_Homo sapiens_hsa043900.49476779
76Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49277720
77Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47320645
78Proteoglycans in cancer_Homo sapiens_hsa052050.46356568
79FoxO signaling pathway_Homo sapiens_hsa040680.45995280
80Prolactin signaling pathway_Homo sapiens_hsa049170.45860307
81mTOR signaling pathway_Homo sapiens_hsa041500.45494311
82Primary immunodeficiency_Homo sapiens_hsa053400.44766996
83T cell receptor signaling pathway_Homo sapiens_hsa046600.44199514
84Melanoma_Homo sapiens_hsa052180.43930784
85Neurotrophin signaling pathway_Homo sapiens_hsa047220.43144216
86Sulfur relay system_Homo sapiens_hsa041220.42361846
87Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.41116098
88Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.40391758
89Influenza A_Homo sapiens_hsa051640.39251658
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.38910719
91Folate biosynthesis_Homo sapiens_hsa007900.37959145
92Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.37627262
93Pyruvate metabolism_Homo sapiens_hsa006200.37605814
94NOD-like receptor signaling pathway_Homo sapiens_hsa046210.35235972
95Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33925424
96Inositol phosphate metabolism_Homo sapiens_hsa005620.32572893
97N-Glycan biosynthesis_Homo sapiens_hsa005100.30012006
98NF-kappa B signaling pathway_Homo sapiens_hsa040640.29724698
99Pentose phosphate pathway_Homo sapiens_hsa000300.29540128
100Carbon metabolism_Homo sapiens_hsa012000.28524118

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