ZNF205

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein retention in ER lumen (GO:0006621)4.37859406
2regulation of mammary gland epithelial cell proliferation (GO:0033599)4.36461751
3planar cell polarity pathway involved in neural tube closure (GO:0090179)4.25650662
4maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.98076350
5semaphorin-plexin signaling pathway (GO:0071526)3.90702060
6adherens junction assembly (GO:0034333)3.84112649
7regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.75754069
8negative regulation of cell size (GO:0045792)3.75224157
9proline biosynthetic process (GO:0006561)3.70514647
10apoptotic process involved in morphogenesis (GO:0060561)3.67669768
11cell-cell junction maintenance (GO:0045217)3.60243942
12negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.43043772
13Golgi transport vesicle coating (GO:0048200)3.41550902
14COPI coating of Golgi vesicle (GO:0048205)3.41550902
15establishment of apical/basal cell polarity (GO:0035089)3.38729812
16cell-substrate adherens junction assembly (GO:0007045)3.37943632
17focal adhesion assembly (GO:0048041)3.37943632
18epithelial cell-cell adhesion (GO:0090136)3.28365713
19basement membrane organization (GO:0071711)3.28168408
20cytoskeletal anchoring at plasma membrane (GO:0007016)3.26675729
21barbed-end actin filament capping (GO:0051016)3.19665178
22protein localization to endosome (GO:0036010)3.14759184
23regulation of early endosome to late endosome transport (GO:2000641)3.13186503
24heterochromatin organization (GO:0070828)3.10863921
25dichotomous subdivision of an epithelial terminal unit (GO:0060600)3.06258789
26convergent extension (GO:0060026)3.02733713
27retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.98675894
28cell-substrate junction assembly (GO:0007044)2.96327109
29establishment or maintenance of monopolar cell polarity (GO:0061339)2.96304509
30establishment of monopolar cell polarity (GO:0061162)2.96304509
31negative regulation of catenin import into nucleus (GO:0035414)2.95917153
32paraxial mesoderm development (GO:0048339)2.95660649
33respiratory system process (GO:0003016)2.87798778
34maternal placenta development (GO:0001893)2.86707704
35cochlea morphogenesis (GO:0090103)2.85314385
36desmosome organization (GO:0002934)2.83338820
37endothelial cell chemotaxis (GO:0035767)2.81433658
38Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.81114672
39skeletal muscle organ development (GO:0060538)2.76618912
40vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.76527455
41cell migration in hindbrain (GO:0021535)2.76009748
42peptidyl-arginine omega-N-methylation (GO:0035247)2.75130865
43regulation of NFAT protein import into nucleus (GO:0051532)2.74856628
44activation of Rac GTPase activity (GO:0032863)2.72170252
45hemidesmosome assembly (GO:0031581)2.71688176
46proline metabolic process (GO:0006560)2.66523710
47atrioventricular valve morphogenesis (GO:0003181)2.64833750
48diaphragm development (GO:0060539)2.64289485
49apoptotic process involved in development (GO:1902742)2.62390984
50tooth mineralization (GO:0034505)2.59479004
51neural tube development (GO:0021915)2.57310282
52regulation of establishment of planar polarity (GO:0090175)2.57027006
53cell junction maintenance (GO:0034331)2.55816084
54regulation of branching involved in prostate gland morphogenesis (GO:0060687)2.54608808
55protein complex localization (GO:0031503)2.54432540
56vascular endothelial growth factor signaling pathway (GO:0038084)2.53468514
57lymph vessel development (GO:0001945)2.52978190
58embryonic skeletal joint morphogenesis (GO:0060272)2.52001313
59negative regulation of chondrocyte differentiation (GO:0032331)2.48498389
60regulation of glucose import in response to insulin stimulus (GO:2001273)2.47170298
61protein insertion into membrane (GO:0051205)2.46023291
62ribosomal small subunit biogenesis (GO:0042274)2.45161978
63neuron projection extension involved in neuron projection guidance (GO:1902284)2.44369448
64axon extension involved in axon guidance (GO:0048846)2.44369448
65protein maturation by protein folding (GO:0022417)2.43861801
66outflow tract septum morphogenesis (GO:0003148)2.43765165
67establishment or maintenance of apical/basal cell polarity (GO:0035088)2.43442867
68establishment or maintenance of bipolar cell polarity (GO:0061245)2.43442867
69regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.43357356
70mammary gland epithelial cell differentiation (GO:0060644)2.42033876
71camera-type eye morphogenesis (GO:0048593)2.41444652
72branching involved in salivary gland morphogenesis (GO:0060445)2.40589121
73axon extension (GO:0048675)2.40562832
74nucleosome disassembly (GO:0006337)2.40547312
75protein-DNA complex disassembly (GO:0032986)2.40547312
76positive regulation of synapse maturation (GO:0090129)2.40322613
77regulation of apoptotic process involved in morphogenesis (GO:1902337)2.39420593
78regulation of cardioblast differentiation (GO:0051890)2.38776253
79UV protection (GO:0009650)2.36836932
80histone arginine methylation (GO:0034969)2.35818224
81mannose metabolic process (GO:0006013)2.34886215
82endothelial cell morphogenesis (GO:0001886)2.34722670
83muscle cell fate commitment (GO:0042693)2.33933729
84negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.33614967
85negative regulation of microtubule polymerization (GO:0031115)2.32914528
86cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.32073929
87regulation of translational fidelity (GO:0006450)2.31891198
88establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.30481746
89GDP-mannose metabolic process (GO:0019673)2.30226054
90stress fiber assembly (GO:0043149)2.29199903
91protein heterotrimerization (GO:0070208)2.29085310
92activation of MAPKKK activity (GO:0000185)2.27919908
93embryo implantation (GO:0007566)2.27847352
94RNA localization (GO:0006403)2.27808678
95regulation of chromatin binding (GO:0035561)2.27471602
96regulation of cholesterol biosynthetic process (GO:0045540)2.26980132
97peptidyl-arginine methylation (GO:0018216)2.26686685
98peptidyl-arginine N-methylation (GO:0035246)2.26686685
99eye morphogenesis (GO:0048592)2.26656017
100regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.25439495

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.89562620
2TP63_17297297_ChIP-ChIP_HaCaT_Human3.38091524
3RARG_19884340_ChIP-ChIP_MEFs_Mouse2.88229949
4LXR_22292898_ChIP-Seq_THP-1_Human2.86701279
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.49765201
6* ELK3_25401928_ChIP-Seq_HUVEC_Human2.40450181
7RACK7_27058665_Chip-Seq_MCF-7_Human2.34950663
8EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.32856936
9ZNF263_19887448_ChIP-Seq_K562_Human2.31388256
10ERG_21242973_ChIP-ChIP_JURKAT_Human2.20174916
11ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.19397403
12TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.18858038
13PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.14268890
14KDM2B_26808549_Chip-Seq_SUP-B15_Human2.06794434
15VDR_21846776_ChIP-Seq_THP-1_Human2.05026437
16KDM2B_26808549_Chip-Seq_K562_Human2.03947566
17ZFP281_18757296_ChIP-ChIP_E14_Mouse1.96433248
18* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.93011977
19TET1_21451524_ChIP-Seq_MESCs_Mouse1.88152783
20ESR2_21235772_ChIP-Seq_MCF-7_Human1.81056599
21P68_20966046_ChIP-Seq_HELA_Human1.79606244
22UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.77350951
23KDM2B_26808549_Chip-Seq_DND41_Human1.74687545
24DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.73674786
25* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.66686818
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.64381486
27HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.63850156
28STAT6_21828071_ChIP-Seq_BEAS2B_Human1.62735119
29TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.62085747
30CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.60751787
31SRY_22984422_ChIP-ChIP_TESTIS_Rat1.59458355
32WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.59260033
33KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.58950104
34SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.54746523
35CTCF_27219007_Chip-Seq_Bcells_Human1.54506731
36SMC4_20622854_ChIP-Seq_HELA_Human1.52475077
37SA1_27219007_Chip-Seq_ERYTHROID_Human1.52181749
38MYC_22102868_ChIP-Seq_BL_Human1.52174706
39CREB1_26743006_Chip-Seq_LNCaP_Human1.50763612
40NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.47663148
41CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.46729617
42* TP53_22127205_ChIP-Seq_IMR90_Human1.46370870
43ESR1_15608294_ChIP-ChIP_MCF-7_Human1.42873807
44ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.42795048
45CTCF_27219007_Chip-Seq_ERYTHROID_Human1.42231314
46RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.41311283
47P300_27058665_Chip-Seq_ZR-75-30cells_Human1.41236125
48TCF7_22412390_ChIP-Seq_EML_Mouse1.39595182
49NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.37409318
50KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.36222298
51DNAJC2_21179169_ChIP-ChIP_NT2_Human1.35412753
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.32983004
53SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.32220965
54CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.32167531
55* XRN2_22483619_ChIP-Seq_HELA_Human1.32017287
56NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.31127930
57ATF3_27146783_Chip-Seq_COLON_Human1.28614131
58KLF4_18555785_ChIP-Seq_MESCs_Mouse1.28438527
59POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.28246537
60CLOCK_20551151_ChIP-Seq_293T_Human1.28165714
61ZFP281_27345836_Chip-Seq_ESCs_Mouse1.28023241
62TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.27038069
63MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.26419206
64KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.26378689
65TP53_20018659_ChIP-ChIP_R1E_Mouse1.24542701
66MYC_18555785_ChIP-Seq_MESCs_Mouse1.22685064
67KDM2B_26808549_Chip-Seq_JURKAT_Human1.21746986
68CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.20793039
69TET1_21490601_ChIP-Seq_MESCs_Mouse1.18245742
70CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.16594162
71SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.16488884
72ZFX_18555785_ChIP-Seq_MESCs_Mouse1.15401001
73SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.14839863
74ELF1_20517297_ChIP-Seq_JURKAT_Human1.12879965
75MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.11964519
76RARA_24833708_ChIP-Seq_LIVER_Mouse1.11344479
77PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.10853140
78MYC_18358816_ChIP-ChIP_MESCs_Mouse1.08719828
79RUNX1_27514584_Chip-Seq_MCF-7_Human1.07686206
80CTCF_18555785_ChIP-Seq_MESCs_Mouse1.07094408
81SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.06338116
82THAP11_20581084_ChIP-Seq_MESCs_Mouse1.06318097
83FOXM1_23109430_ChIP-Seq_U2OS_Human1.05219060
84FOXP1_21924763_ChIP-Seq_HESCs_Human1.04636653
85KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.04072608
86SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.03885675
87STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.03711948
88ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.02760723
89UBF1/2_26484160_Chip-Seq_HMECs_Human1.02716355
90MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.01866492
91TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01672641
92TRIM28_21343339_ChIP-Seq_HEK293_Human1.01613677
93KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.00957775
94MYC_19079543_ChIP-ChIP_MESCs_Mouse0.99721590
95* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99271106
96BCOR_27268052_Chip-Seq_Bcells_Human0.98857935
97PHF8_20622854_ChIP-Seq_HELA_Human0.98639129
98NCOR1_26117541_ChIP-Seq_K562_Human0.97420715
99TP63_22573176_ChIP-Seq_HFKS_Human0.96994165
100SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.96753417

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003705_abnormal_hypodermis_morpholog4.64975331
2MP0010030_abnormal_orbit_morphology3.46854254
3MP0001849_ear_inflammation2.73074399
4MP0002249_abnormal_larynx_morphology2.68002266
5MP0000537_abnormal_urethra_morphology2.53906490
6MP0004272_abnormal_basement_membrane2.46930276
7MP0004858_abnormal_nervous_system2.41697543
8MP0005058_abnormal_lysosome_morphology2.34371717
9MP0005257_abnormal_intraocular_pressure2.32936517
10MP0000678_abnormal_parathyroid_gland2.32617295
11MP0005623_abnormal_meninges_morphology2.25517396
12MP0008438_abnormal_cutaneous_collagen2.15100128
13MP0000751_myopathy2.05666220
14MP0005451_abnormal_body_composition1.95023302
15MP0004233_abnormal_muscle_weight1.93142859
16MP0005076_abnormal_cell_differentiation1.84217448
17MP0004185_abnormal_adipocyte_glucose1.84053097
18MP0010368_abnormal_lymphatic_system1.83517332
19MP0005409_darkened_coat_color1.75897033
20MP0003566_abnormal_cell_adhesion1.75085971
21MP0002796_impaired_skin_barrier1.74122467
22MP0003123_paternal_imprinting1.73933627
23MP0010234_abnormal_vibrissa_follicle1.70586457
24MP0000003_abnormal_adipose_tissue1.69136225
25MP0000049_abnormal_middle_ear1.65420335
26MP0009053_abnormal_anal_canal1.61939318
27MP0002089_abnormal_postnatal_growth/wei1.60479921
28MP0000733_abnormal_muscle_development1.59524456
29MP0005501_abnormal_skin_physiology1.55076047
30MP0009840_abnormal_foam_cell1.55036470
31MP0002877_abnormal_melanocyte_morpholog1.54853684
32MP0003942_abnormal_urinary_system1.54794839
33MP0000566_synostosis1.54395157
34MP0003453_abnormal_keratinocyte_physiol1.53675704
35MP0000579_abnormal_nail_morphology1.50301238
36MP0000747_muscle_weakness1.41970444
37MP0008260_abnormal_autophagy1.39648689
38MP0000013_abnormal_adipose_tissue1.33050931
39MP0000750_abnormal_muscle_regeneration1.32521330
40MP0001348_abnormal_lacrimal_gland1.32204551
41MP0000534_abnormal_ureter_morphology1.30535476
42MP0009384_cardiac_valve_regurgitation1.30528737
43MP0000759_abnormal_skeletal_muscle1.30038544
44MP0000762_abnormal_tongue_morphology1.27757758
45MP0005375_adipose_tissue_phenotype1.24895210
46MP0003385_abnormal_body_wall1.23252310
47MP0002697_abnormal_eye_size1.18242989
48MP0000467_abnormal_esophagus_morphology1.13363517
49MP0003279_aneurysm1.12263984
50MP0004087_abnormal_muscle_fiber1.11438043
51MP0005508_abnormal_skeleton_morphology1.11428752
52MP0002060_abnormal_skin_morphology1.11316160
53MP0004859_abnormal_synaptic_plasticity1.10917997
54MP0000767_abnormal_smooth_muscle1.09033473
55MP0000462_abnormal_digestive_system1.07303618
56MP0003315_abnormal_perineum_morphology1.06279612
57MP0000749_muscle_degeneration1.06247688
58MP0009250_abnormal_appendicular_skeleto1.06179953
59MP0005330_cardiomyopathy1.04482396
60MP0005666_abnormal_adipose_tissue1.03909069
61MP0002092_abnormal_eye_morphology1.03373792
62MP0009672_abnormal_birth_weight1.02846843
63MP0006138_congestive_heart_failure1.02074109
64MP0005503_abnormal_tendon_morphology1.01415879
65MP0001661_extended_life_span1.01191236
66MP0002932_abnormal_joint_morphology1.00397428
67MP0002116_abnormal_craniofacial_bone0.99846816
68MP0009379_abnormal_foot_pigmentation0.99824312
69MP0002098_abnormal_vibrissa_morphology0.99419739
70MP0003329_amyloid_beta_deposits0.98718750
71MP0010630_abnormal_cardiac_muscle0.97668424
72MP0000681_abnormal_thyroid_gland0.97604307
73MP0001730_embryonic_growth_arrest0.96273930
74MP0005670_abnormal_white_adipose0.95948573
75MP0001299_abnormal_eye_distance/0.94896877
76MP0003091_abnormal_cell_migration0.90579213
77MP0000428_abnormal_craniofacial_morphol0.88607791
78MP0009780_abnormal_chondrocyte_physiolo0.87830726
79MP0002085_abnormal_embryonic_tissue0.86867302
80MP0003879_abnormal_hair_cell0.86519228
81MP0002896_abnormal_bone_mineralization0.85422842
82MP0002114_abnormal_axial_skeleton0.85320816
83MP0003115_abnormal_respiratory_system0.84814061
84MP0002254_reproductive_system_inflammat0.84071892
85MP0003935_abnormal_craniofacial_develop0.83780757
86MP0002269_muscular_atrophy0.83681904
87MP0003634_abnormal_glial_cell0.82707996
88MP0002111_abnormal_tail_morphology0.81543914
89MP0003283_abnormal_digestive_organ0.81434861
90MP0002108_abnormal_muscle_morphology0.80758731
91MP0001340_abnormal_eyelid_morphology0.78619785
92MP0003861_abnormal_nervous_system0.77936299
93MP0003693_abnormal_embryo_hatching0.76723112
94MP0003755_abnormal_palate_morphology0.76529279
95MP0005023_abnormal_wound_healing0.75290025
96MP0008932_abnormal_embryonic_tissue0.74369259
97MP0003941_abnormal_skin_development0.73119456
98MP0002080_prenatal_lethality0.72993456
99MP0001346_abnormal_lacrimal_gland0.71167177
100MP0001958_emphysema0.70886013

Predicted human phenotypes

RankGene SetZ-score
1Ulnar bowing (HP:0003031)3.57666766
2Hyperacusis (HP:0010780)3.48292990
3Premature rupture of membranes (HP:0001788)3.38805259
4Protrusio acetabuli (HP:0003179)3.34659797
5Spinal rigidity (HP:0003306)3.00604122
6Stridor (HP:0010307)2.91797151
7Shallow orbits (HP:0000586)2.87492873
8Achilles tendon contracture (HP:0001771)2.86617401
9Upper limb amyotrophy (HP:0009129)2.76655893
10Distal upper limb amyotrophy (HP:0007149)2.76655893
11Turricephaly (HP:0000262)2.73779471
12Myopathic facies (HP:0002058)2.65216489
13Increased connective tissue (HP:0009025)2.59916492
14Cerebral aneurysm (HP:0004944)2.55156716
15Thin bony cortex (HP:0002753)2.54881460
16Distal lower limb amyotrophy (HP:0008944)2.51833547
17Abnormality of the Achilles tendon (HP:0005109)2.51550363
18Centrally nucleated skeletal muscle fibers (HP:0003687)2.48672343
19Broad distal phalanx of finger (HP:0009836)2.45844246
20Cervical subluxation (HP:0003308)2.32021616
21Mildly elevated creatine phosphokinase (HP:0008180)2.30793174
22Long palpebral fissure (HP:0000637)2.30201460
23Insomnia (HP:0100785)2.29688528
24Vertebral compression fractures (HP:0002953)2.29050451
25Obstructive sleep apnea (HP:0002870)2.26521892
26Mitral regurgitation (HP:0001653)2.23803400
27Distal lower limb muscle weakness (HP:0009053)2.23529505
28Fragile skin (HP:0001030)2.22744445
29Bulbar palsy (HP:0001283)2.22238564
30J-shaped sella turcica (HP:0002680)2.22026561
31Biconcave vertebral bodies (HP:0004586)2.20397615
32Increased variability in muscle fiber diameter (HP:0003557)2.20135510
33Broad face (HP:0000283)2.18984501
34Difficulty climbing stairs (HP:0003551)2.18365825
35Abnormality of the aortic arch (HP:0012303)2.17485928
36Short nail (HP:0001799)2.15484910
37Disproportionate tall stature (HP:0001519)2.13738965
38Hyperthyroidism (HP:0000836)2.12836131
39Hand muscle atrophy (HP:0009130)2.11196607
40Lymphangioma (HP:0100764)2.10594360
41Abnormality of the thoracic spine (HP:0100711)2.09933826
42Abnormality of the umbilical cord (HP:0010881)2.08164324
43Atrophic scars (HP:0001075)2.05035890
44Bowed forearm bones (HP:0003956)2.04615991
45Bowing of the arm (HP:0006488)2.04615991
46Axonal loss (HP:0003447)2.03691727
47Bladder diverticulum (HP:0000015)2.03395850
48Diaphragmatic weakness (HP:0009113)2.02785689
49Thin ribs (HP:0000883)2.01355400
50Genu recurvatum (HP:0002816)2.00645098
51Atelectasis (HP:0100750)1.99185026
52Elbow flexion contracture (HP:0002987)1.98493068
53Lower limb amyotrophy (HP:0007210)1.96188200
54Congenital glaucoma (HP:0001087)1.95031608
55Truncus arteriosus (HP:0001660)1.94066805
56Trismus (HP:0000211)1.92747622
57Generalized amyotrophy (HP:0003700)1.91989949
58Selective tooth agenesis (HP:0001592)1.90043612
59Aplasia/Hypoplasia of the sacrum (HP:0008517)1.89599887
60Coronal craniosynostosis (HP:0004440)1.89142975
61Natal tooth (HP:0000695)1.88765666
62Renal duplication (HP:0000075)1.88681713
63Type 1 muscle fiber predominance (HP:0003803)1.87114805
64Abnormality of skeletal muscle fiber size (HP:0012084)1.85941146
65Pterygium (HP:0001059)1.85717718
66Abnormality of the distal phalanges of the toes (HP:0010182)1.85380549
67Abnormality of the fetal cardiovascular system (HP:0010948)1.84313034
68Abnormal umbilical cord blood vessels (HP:0011403)1.84313034
69Single umbilical artery (HP:0001195)1.84313034
70Thoracic kyphosis (HP:0002942)1.83918935
71Pointed chin (HP:0000307)1.83696494
72Back pain (HP:0003418)1.83053900
73Nuclear cataract (HP:0100018)1.83040471
74Broad metatarsal (HP:0001783)1.83007203
75Abnormality of the phalanges of the hallux (HP:0010057)1.80718149
76Flat acetabular roof (HP:0003180)1.80073568
77Advanced eruption of teeth (HP:0006288)1.79924008
78Abnormality of dentin (HP:0010299)1.79097956
79Blue sclerae (HP:0000592)1.75656234
80Asymmetry of the thorax (HP:0001555)1.74951747
81Hyperparathyroidism (HP:0000843)1.74831576
82Abnormality of the tricuspid valve (HP:0001702)1.74651115
83Ankle contracture (HP:0006466)1.73951541
84Patellar dislocation (HP:0002999)1.73402791
85Round ear (HP:0100830)1.72133537
86Bronchomalacia (HP:0002780)1.69547867
87Hypoventilation (HP:0002791)1.69321269
88Exercise-induced myalgia (HP:0003738)1.69301948
89High anterior hairline (HP:0009890)1.67755727
90Premature skin wrinkling (HP:0100678)1.67299144
91Abnormality of the distal phalanx of the thumb (HP:0009617)1.66470391
92Elfin facies (HP:0004428)1.65619937
93Overriding aorta (HP:0002623)1.64536657
94Aplasia involving bones of the upper limbs (HP:0009823)1.63587446
95Aplasia of the phalanges of the hand (HP:0009802)1.63587446
96Aplasia involving bones of the extremities (HP:0009825)1.63587446
97Hypoplasia of the capital femoral epiphysis (HP:0003090)1.62383034
98Long toe (HP:0010511)1.62214882
99Lumbar hyperlordosis (HP:0002938)1.60156870
100Arnold-Chiari malformation (HP:0002308)1.59067780

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB35.07855208
2SIK13.59180086
3EEF2K3.52024050
4SMG13.14153040
5ICK3.12598653
6IRAK32.95382286
7NME22.76199168
8EPHA22.64416177
9RIPK12.34433007
10EPHB22.16381539
11TTN2.02780088
12PKN21.85947303
13PRKD31.84541424
14LATS21.68029822
15PDGFRA1.60341017
16TESK11.57570677
17MST1R1.52518276
18PTK21.47681036
19NTRK11.45097235
20RPS6KA21.44759741
21PRPF4B1.44721352
22ARAF1.42730176
23MAP3K101.38324619
24PAK41.37434672
25MTOR1.34020232
26ERN11.30996019
27MARK21.16221763
28BRAF1.16068500
29LMTK21.10515828
30CDK121.06142842
31ILK1.05052160
32MET1.02979611
33MAPK151.02586802
34FGFR41.01716797
35PRKD21.01369638
36DDR21.01277325
37KDR0.97517923
38MAP3K110.95909830
39TYRO30.94488915
40PIM20.91348306
41RPS6KL10.89877675
42RPS6KC10.89877675
43TAOK20.89655429
44PTK60.89180056
45NEK20.87673275
46CDC42BPA0.86008185
47RPS6KB20.84561302
48BMX0.81965768
49MUSK0.80925766
50AURKA0.80088821
51IRAK20.79410010
52PRKG20.77581961
53AKT20.76515218
54DAPK30.76077584
55MAP3K60.70989736
56ABL20.69564272
57CDK70.69356305
58SIK20.69292606
59DMPK0.68672968
60BRSK10.66940740
61RPS6KA60.65989312
62PRKCI0.64574211
63PDPK10.64018882
64MAP2K20.63689208
65CAMK1D0.62497230
66LIMK10.59948693
67PHKG10.59448240
68PHKG20.59448240
69PAK20.58810403
70MAP3K90.58628063
71EPHB10.58295296
72MAP3K10.56959685
73MAPKAPK30.56002825
74MAP2K30.55824132
75MAP3K80.53197684
76DYRK1B0.52400745
77TIE10.51531674
78CDK11A0.50773707
79RPS6KA10.49601775
80CAMK2G0.49559266
81PAK10.48226584
82CDK150.46342471
83TESK20.45992120
84DYRK30.45248466
85NME10.42953775
86CDK140.40363024
87STK380.40131106
88MAP3K30.39836226
89CDK180.39283695
90MOS0.37105277
91LRRK20.36629458
92CDK80.34766169
93CHEK20.34259691
94TAOK10.33938015
95HIPK20.32279065
96CAMKK10.32067370
97MAPK110.31589037
98CSNK1G30.31296931
99SIK30.31069276
100CAMK2B0.30852397

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur relay system_Homo sapiens_hsa041223.17167755
2Notch signaling pathway_Homo sapiens_hsa043302.27458966
3Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005322.16282020
4Other glycan degradation_Homo sapiens_hsa005111.99640555
5Bladder cancer_Homo sapiens_hsa052191.92574846
62-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.92219707
7Vitamin B6 metabolism_Homo sapiens_hsa007501.91388627
8Biosynthesis of amino acids_Homo sapiens_hsa012301.86202725
9Central carbon metabolism in cancer_Homo sapiens_hsa052301.84943299
10Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.73160792
11Fructose and mannose metabolism_Homo sapiens_hsa000511.70616659
12Galactose metabolism_Homo sapiens_hsa000521.69255483
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.52801282
14Glycosaminoglycan degradation_Homo sapiens_hsa005311.51654555
15Cyanoamino acid metabolism_Homo sapiens_hsa004601.49795562
16Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.49350471
17Prion diseases_Homo sapiens_hsa050201.47140222
18Pentose phosphate pathway_Homo sapiens_hsa000301.43601377
19Basal cell carcinoma_Homo sapiens_hsa052171.43164317
20ECM-receptor interaction_Homo sapiens_hsa045121.41081163
21Chronic myeloid leukemia_Homo sapiens_hsa052201.39128423
22VEGF signaling pathway_Homo sapiens_hsa043701.36803386
23AMPK signaling pathway_Homo sapiens_hsa041521.35438686
24Focal adhesion_Homo sapiens_hsa045101.31244338
25Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.29954199
26Hippo signaling pathway_Homo sapiens_hsa043901.27056535
27Axon guidance_Homo sapiens_hsa043601.25342947
28Insulin signaling pathway_Homo sapiens_hsa049101.24285647
29Longevity regulating pathway - mammal_Homo sapiens_hsa042111.24080147
30Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.22630392
31Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.22501380
32Arginine biosynthesis_Homo sapiens_hsa002201.19818515
33Endometrial cancer_Homo sapiens_hsa052131.19230448
34Thyroid hormone signaling pathway_Homo sapiens_hsa049191.16562750
35Dilated cardiomyopathy_Homo sapiens_hsa054141.15888162
36Arginine and proline metabolism_Homo sapiens_hsa003301.14317593
37Hedgehog signaling pathway_Homo sapiens_hsa043401.13211589
38Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.10307955
39Glioma_Homo sapiens_hsa052141.08767047
40Vibrio cholerae infection_Homo sapiens_hsa051101.07361225
41Thyroid cancer_Homo sapiens_hsa052161.06106207
42mTOR signaling pathway_Homo sapiens_hsa041501.05725761
43Neurotrophin signaling pathway_Homo sapiens_hsa047221.05323002
44Melanogenesis_Homo sapiens_hsa049161.03126439
45ErbB signaling pathway_Homo sapiens_hsa040121.00155706
46Tight junction_Homo sapiens_hsa045300.99087831
47Proteoglycans in cancer_Homo sapiens_hsa052050.95755174
48Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.95585177
49Carbon metabolism_Homo sapiens_hsa012000.93859747
50Phenylalanine metabolism_Homo sapiens_hsa003600.88252649
51Estrogen signaling pathway_Homo sapiens_hsa049150.88115078
52Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87858526
53Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.87804320
54Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.87493816
55Adherens junction_Homo sapiens_hsa045200.87262926
56Non-small cell lung cancer_Homo sapiens_hsa052230.83804213
57Lysosome_Homo sapiens_hsa041420.82009002
58Acute myeloid leukemia_Homo sapiens_hsa052210.81495175
59MicroRNAs in cancer_Homo sapiens_hsa052060.80079363
60Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.79743409
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.78945489
62Lysine degradation_Homo sapiens_hsa003100.78796387
63Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78705362
64Pancreatic cancer_Homo sapiens_hsa052120.76776138
65Small cell lung cancer_Homo sapiens_hsa052220.76152182
66Base excision repair_Homo sapiens_hsa034100.76053675
67Synaptic vesicle cycle_Homo sapiens_hsa047210.75892115
68Gap junction_Homo sapiens_hsa045400.75243163
69GnRH signaling pathway_Homo sapiens_hsa049120.73183668
70Wnt signaling pathway_Homo sapiens_hsa043100.71733950
71Melanoma_Homo sapiens_hsa052180.71164345
72Renal cell carcinoma_Homo sapiens_hsa052110.70800303
73Endocytosis_Homo sapiens_hsa041440.69770119
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.68136408
75Glucagon signaling pathway_Homo sapiens_hsa049220.67544645
76Amoebiasis_Homo sapiens_hsa051460.65624369
77Phospholipase D signaling pathway_Homo sapiens_hsa040720.62220484
78DNA replication_Homo sapiens_hsa030300.61052632
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58614615
80Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58132188
81Colorectal cancer_Homo sapiens_hsa052100.57995647
82AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57143499
83Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56653609
84Rap1 signaling pathway_Homo sapiens_hsa040150.56324975
85Insulin resistance_Homo sapiens_hsa049310.55459251
86Pathways in cancer_Homo sapiens_hsa052000.55279107
87Choline metabolism in cancer_Homo sapiens_hsa052310.54580662
88Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54568945
89Adipocytokine signaling pathway_Homo sapiens_hsa049200.53294318
90Alcoholism_Homo sapiens_hsa050340.52039747
91Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.50369430
92Prostate cancer_Homo sapiens_hsa052150.49173147
93Apoptosis_Homo sapiens_hsa042100.48770570
94PI3K-Akt signaling pathway_Homo sapiens_hsa041510.48647987
95Sphingolipid signaling pathway_Homo sapiens_hsa040710.47883434
96N-Glycan biosynthesis_Homo sapiens_hsa005100.47242855
97mRNA surveillance pathway_Homo sapiens_hsa030150.46320537
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.43896059
99Inositol phosphate metabolism_Homo sapiens_hsa005620.43441852
100Sphingolipid metabolism_Homo sapiens_hsa006000.40204887

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »