Rank | Gene Set | Z-score |
---|---|---|
1 | behavioral response to nicotine (GO:0035095) | 4.72707114 |
2 | response to pheromone (GO:0019236) | 4.14865301 |
3 | negative regulation of telomere maintenance (GO:0032205) | 4.06527904 |
4 | protein-cofactor linkage (GO:0018065) | 3.79716747 |
5 | platelet dense granule organization (GO:0060155) | 3.74082940 |
6 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.65342916 |
7 | NADH dehydrogenase complex assembly (GO:0010257) | 3.65342916 |
8 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.65342916 |
9 | protein complex biogenesis (GO:0070271) | 3.60995464 |
10 | otic vesicle formation (GO:0030916) | 3.52698685 |
11 | DNA deamination (GO:0045006) | 3.41039526 |
12 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.38525769 |
13 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.34931066 |
14 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.31079392 |
15 | kidney morphogenesis (GO:0060993) | 3.29154884 |
16 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.19520588 |
17 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.17214853 |
18 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.17214853 |
19 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.17214853 |
20 | regulation of gene silencing by miRNA (GO:0060964) | 3.13617017 |
21 | regulation of gene silencing by RNA (GO:0060966) | 3.13617017 |
22 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.13617017 |
23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.12732379 |
24 | kynurenine metabolic process (GO:0070189) | 3.11993584 |
25 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.10090304 |
26 | sulfation (GO:0051923) | 3.09556308 |
27 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.05211391 |
28 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.03525974 |
29 | ATP synthesis coupled proton transport (GO:0015986) | 3.03525974 |
30 | L-fucose catabolic process (GO:0042355) | 2.98955735 |
31 | fucose catabolic process (GO:0019317) | 2.98955735 |
32 | L-fucose metabolic process (GO:0042354) | 2.98955735 |
33 | replication fork processing (GO:0031297) | 2.97638817 |
34 | epithelial cilium movement (GO:0003351) | 2.96079955 |
35 | cullin deneddylation (GO:0010388) | 2.94948839 |
36 | maturation of 5.8S rRNA (GO:0000460) | 2.94438201 |
37 | tryptophan catabolic process (GO:0006569) | 2.94093712 |
38 | indole-containing compound catabolic process (GO:0042436) | 2.94093712 |
39 | indolalkylamine catabolic process (GO:0046218) | 2.94093712 |
40 | cellular ketone body metabolic process (GO:0046950) | 2.93482754 |
41 | regulation of telomere maintenance (GO:0032204) | 2.91449468 |
42 | indolalkylamine metabolic process (GO:0006586) | 2.89533891 |
43 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.86069814 |
44 | respiratory chain complex IV assembly (GO:0008535) | 2.85472986 |
45 | somite development (GO:0061053) | 2.85011023 |
46 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.83338540 |
47 | nonmotile primary cilium assembly (GO:0035058) | 2.82780543 |
48 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.80122527 |
49 | regulation of helicase activity (GO:0051095) | 2.76019735 |
50 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.75293363 |
51 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.72958521 |
52 | protein deneddylation (GO:0000338) | 2.72695838 |
53 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.72327838 |
54 | photoreceptor cell maintenance (GO:0045494) | 2.70366797 |
55 | glycerophospholipid catabolic process (GO:0046475) | 2.70360133 |
56 | ketone body metabolic process (GO:1902224) | 2.70072522 |
57 | regulation of mesoderm development (GO:2000380) | 2.69301325 |
58 | synapsis (GO:0007129) | 2.65928243 |
59 | retinal cone cell development (GO:0046549) | 2.65222887 |
60 | DNA double-strand break processing (GO:0000729) | 2.64851400 |
61 | regulation of action potential (GO:0098900) | 2.63998433 |
62 | piRNA metabolic process (GO:0034587) | 2.63774026 |
63 | male meiosis I (GO:0007141) | 2.62717787 |
64 | protein neddylation (GO:0045116) | 2.60102503 |
65 | electron transport chain (GO:0022900) | 2.60063329 |
66 | DNA damage response, detection of DNA damage (GO:0042769) | 2.59422001 |
67 | centriole replication (GO:0007099) | 2.58815918 |
68 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.58808005 |
69 | detection of light stimulus involved in visual perception (GO:0050908) | 2.58808005 |
70 | cilium morphogenesis (GO:0060271) | 2.58327869 |
71 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.57108807 |
72 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.57108807 |
73 | protein localization to cilium (GO:0061512) | 2.56678038 |
74 | dopamine transport (GO:0015872) | 2.56591619 |
75 | reciprocal meiotic recombination (GO:0007131) | 2.56512328 |
76 | reciprocal DNA recombination (GO:0035825) | 2.56512328 |
77 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.55807416 |
78 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.55807416 |
79 | reflex (GO:0060004) | 2.54765809 |
80 | respiratory electron transport chain (GO:0022904) | 2.54720857 |
81 | adaptation of signaling pathway (GO:0023058) | 2.53971524 |
82 | single strand break repair (GO:0000012) | 2.53791495 |
83 | recombinational repair (GO:0000725) | 2.52968529 |
84 | cytochrome complex assembly (GO:0017004) | 2.52700109 |
85 | tryptophan metabolic process (GO:0006568) | 2.52281484 |
86 | spinal cord motor neuron differentiation (GO:0021522) | 2.52013268 |
87 | double-strand break repair via homologous recombination (GO:0000724) | 2.49293244 |
88 | resolution of meiotic recombination intermediates (GO:0000712) | 2.49106327 |
89 | peptidyl-histidine modification (GO:0018202) | 2.46351784 |
90 | regulation of meiosis I (GO:0060631) | 2.45624040 |
91 | neuronal action potential (GO:0019228) | 2.45334641 |
92 | axoneme assembly (GO:0035082) | 2.43085909 |
93 | synaptic transmission, cholinergic (GO:0007271) | 2.42957913 |
94 | rRNA catabolic process (GO:0016075) | 2.42824860 |
95 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.41889330 |
96 | regulation of glucokinase activity (GO:0033131) | 2.41709708 |
97 | regulation of hexokinase activity (GO:1903299) | 2.41709708 |
98 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.41463436 |
99 | photoreceptor cell development (GO:0042461) | 2.41419458 |
100 | telomere maintenance via telomerase (GO:0007004) | 2.40948962 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.73481102 |
2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.33939486 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.95576330 |
4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.71813449 |
5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.50200108 |
6 | FUS_26573619_Chip-Seq_HEK293_Human | 2.39833306 |
7 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.39004794 |
8 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.38711760 |
9 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.33498054 |
10 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.32663674 |
11 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.32402954 |
12 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.28155498 |
13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.28154474 |
14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.25067453 |
15 | EWS_26573619_Chip-Seq_HEK293_Human | 2.22793652 |
16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.21850173 |
17 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.18623235 |
18 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.13861527 |
19 | P300_19829295_ChIP-Seq_ESCs_Human | 2.13071083 |
20 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.01442047 |
21 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.00073371 |
22 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.97233298 |
23 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.93949409 |
24 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.87097941 |
25 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.86308247 |
26 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.82256364 |
27 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.78465111 |
28 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.73849439 |
29 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.71008338 |
30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.60920382 |
31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.55749067 |
32 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.54500191 |
33 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.54135629 |
34 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.50606337 |
35 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.50059002 |
36 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.49386338 |
37 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.45662932 |
38 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.45122764 |
39 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.44737619 |
40 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.44644105 |
41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.44485157 |
42 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.42600796 |
43 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.41890445 |
44 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.41890445 |
45 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.41254782 |
46 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.41115009 |
47 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.41017504 |
48 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40748306 |
49 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.39920376 |
50 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.39830326 |
51 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.39738307 |
52 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.39153025 |
53 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.39153025 |
54 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.38977384 |
55 | * TCF4_23295773_ChIP-Seq_U87_Human | 1.38173645 |
56 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.34684037 |
57 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.34307673 |
58 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.33368993 |
59 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.33117827 |
60 | AR_25329375_ChIP-Seq_VCAP_Human | 1.32761355 |
61 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.31285267 |
62 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.31149908 |
63 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.30509663 |
64 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.30509663 |
65 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.27652373 |
66 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.27482459 |
67 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.27014537 |
68 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.27014537 |
69 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.24266502 |
70 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21906014 |
71 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.20753802 |
72 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.19884415 |
73 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.17653816 |
74 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.17075939 |
75 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.14801491 |
76 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.13734813 |
77 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.12877119 |
78 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.08545969 |
79 | NCOR_22424771_ChIP-Seq_293T_Human | 1.07658123 |
80 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.07002548 |
81 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.06530291 |
82 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.06306949 |
83 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.05970877 |
84 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.04656585 |
85 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.04358733 |
86 | AR_20517297_ChIP-Seq_VCAP_Human | 1.03248329 |
87 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02313613 |
88 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.02178195 |
89 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.01466982 |
90 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.99198727 |
91 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.99082900 |
92 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.98967663 |
93 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.97930369 |
94 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.97550737 |
95 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.97381889 |
96 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.96617014 |
97 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.95737820 |
98 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.95175613 |
99 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.94401384 |
100 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.93450504 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008877_abnormal_DNA_methylation | 3.21456252 |
2 | MP0006292_abnormal_olfactory_placode | 2.67938580 |
3 | MP0002837_dystrophic_cardiac_calcinosis | 2.53693583 |
4 | MP0003195_calcinosis | 2.52515124 |
5 | MP0003136_yellow_coat_color | 2.47611864 |
6 | MP0004133_heterotaxia | 2.29108621 |
7 | MP0005551_abnormal_eye_electrophysiolog | 2.23906039 |
8 | MP0002736_abnormal_nociception_after | 2.19917711 |
9 | MP0006072_abnormal_retinal_apoptosis | 2.19852036 |
10 | MP0001968_abnormal_touch/_nociception | 2.11519181 |
11 | MP0009046_muscle_twitch | 2.06760917 |
12 | MP0003880_abnormal_central_pattern | 2.04742823 |
13 | MP0002102_abnormal_ear_morphology | 2.02478372 |
14 | MP0003787_abnormal_imprinting | 1.98101232 |
15 | MP0001986_abnormal_taste_sensitivity | 1.98087642 |
16 | MP0002876_abnormal_thyroid_physiology | 1.92597443 |
17 | MP0002938_white_spotting | 1.85484502 |
18 | MP0002254_reproductive_system_inflammat | 1.84366227 |
19 | MP0003646_muscle_fatigue | 1.83120611 |
20 | MP0003890_abnormal_embryonic-extraembry | 1.82443099 |
21 | MP0005646_abnormal_pituitary_gland | 1.77755613 |
22 | MP0000631_abnormal_neuroendocrine_gland | 1.74184143 |
23 | MP0000569_abnormal_digit_pigmentation | 1.73102001 |
24 | MP0006276_abnormal_autonomic_nervous | 1.65461021 |
25 | MP0001984_abnormal_olfaction | 1.65092024 |
26 | MP0003718_maternal_effect | 1.64695434 |
27 | MP0009745_abnormal_behavioral_response | 1.64164759 |
28 | MP0005253_abnormal_eye_physiology | 1.62114204 |
29 | MP0001485_abnormal_pinna_reflex | 1.60690336 |
30 | MP0008872_abnormal_physiological_respon | 1.56953128 |
31 | MP0002272_abnormal_nervous_system | 1.55706969 |
32 | MP0005645_abnormal_hypothalamus_physiol | 1.54106737 |
33 | MP0004147_increased_porphyrin_level | 1.54059416 |
34 | MP0008995_early_reproductive_senescence | 1.52387550 |
35 | MP0004885_abnormal_endolymph | 1.49266990 |
36 | MP0000427_abnormal_hair_cycle | 1.49215033 |
37 | MP0003011_delayed_dark_adaptation | 1.44652279 |
38 | MP0008058_abnormal_DNA_repair | 1.43695219 |
39 | MP0008875_abnormal_xenobiotic_pharmacok | 1.41766999 |
40 | MP0001486_abnormal_startle_reflex | 1.40638293 |
41 | MP0003283_abnormal_digestive_organ | 1.40306310 |
42 | MP0002638_abnormal_pupillary_reflex | 1.39859724 |
43 | MP0004142_abnormal_muscle_tone | 1.38611991 |
44 | MP0002163_abnormal_gland_morphology | 1.36923587 |
45 | MP0002735_abnormal_chemical_nociception | 1.36697140 |
46 | MP0002277_abnormal_respiratory_mucosa | 1.28545504 |
47 | MP0000372_irregular_coat_pigmentation | 1.28442023 |
48 | MP0001293_anophthalmia | 1.23455649 |
49 | MP0004742_abnormal_vestibular_system | 1.21581339 |
50 | MP0002557_abnormal_social/conspecific_i | 1.19654295 |
51 | MP0002572_abnormal_emotion/affect_behav | 1.15389330 |
52 | MP0005379_endocrine/exocrine_gland_phen | 1.12181876 |
53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.11431881 |
54 | MP0005174_abnormal_tail_pigmentation | 1.10625130 |
55 | MP0002064_seizures | 1.10350869 |
56 | MP0002160_abnormal_reproductive_system | 1.10268429 |
57 | MP0000383_abnormal_hair_follicle | 1.10171050 |
58 | MP0005389_reproductive_system_phenotype | 1.07932089 |
59 | MP0001501_abnormal_sleep_pattern | 1.07681804 |
60 | MP0003121_genomic_imprinting | 1.06874140 |
61 | MP0002734_abnormal_mechanical_nocicepti | 1.06287916 |
62 | MP0004215_abnormal_myocardial_fiber | 1.05409987 |
63 | MP0003937_abnormal_limbs/digits/tail_de | 1.04508974 |
64 | MP0003119_abnormal_digestive_system | 1.03445120 |
65 | MP0001529_abnormal_vocalization | 1.02954868 |
66 | MP0002067_abnormal_sensory_capabilities | 1.02924450 |
67 | MP0005195_abnormal_posterior_eye | 1.01498960 |
68 | MP0000647_abnormal_sebaceous_gland | 1.01275749 |
69 | MP0005410_abnormal_fertilization | 1.01107394 |
70 | MP0002751_abnormal_autonomic_nervous | 1.01053885 |
71 | MP0003635_abnormal_synaptic_transmissio | 0.99536469 |
72 | MP0005075_abnormal_melanosome_morpholog | 0.97622198 |
73 | MP0002210_abnormal_sex_determination | 0.95569419 |
74 | MP0001970_abnormal_pain_threshold | 0.95450622 |
75 | MP0010386_abnormal_urinary_bladder | 0.94125760 |
76 | MP0003698_abnormal_male_reproductive | 0.93835673 |
77 | MP0001929_abnormal_gametogenesis | 0.93602768 |
78 | MP0002733_abnormal_thermal_nociception | 0.92467064 |
79 | MP0005084_abnormal_gallbladder_morpholo | 0.91981081 |
80 | MP0003122_maternal_imprinting | 0.90622246 |
81 | MP0005377_hearing/vestibular/ear_phenot | 0.89624793 |
82 | MP0003878_abnormal_ear_physiology | 0.89624793 |
83 | MP0003938_abnormal_ear_development | 0.89438343 |
84 | MP0001919_abnormal_reproductive_system | 0.89327851 |
85 | MP0002063_abnormal_learning/memory/cond | 0.88402695 |
86 | MP0001324_abnormal_eye_pigmentation | 0.85849179 |
87 | MP0004043_abnormal_pH_regulation | 0.84800872 |
88 | MP0004145_abnormal_muscle_electrophysio | 0.84229366 |
89 | MP0004924_abnormal_behavior | 0.84209425 |
90 | MP0005386_behavior/neurological_phenoty | 0.84209425 |
91 | MP0002653_abnormal_ependyma_morphology | 0.84137432 |
92 | MP0000653_abnormal_sex_gland | 0.84069958 |
93 | MP0002752_abnormal_somatic_nervous | 0.83876492 |
94 | MP0008775_abnormal_heart_ventricle | 0.83739107 |
95 | MP0000778_abnormal_nervous_system | 0.82965707 |
96 | MP0000230_abnormal_systemic_arterial | 0.82323953 |
97 | MP0003137_abnormal_impulse_conducting | 0.81766944 |
98 | MP0001905_abnormal_dopamine_level | 0.80075225 |
99 | MP0001188_hyperpigmentation | 0.79956529 |
100 | MP0005332_abnormal_amino_acid | 0.79561197 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Pancreatic cysts (HP:0001737) | 4.07981114 |
2 | Pancreatic fibrosis (HP:0100732) | 3.85672063 |
3 | Molar tooth sign on MRI (HP:0002419) | 3.68755143 |
4 | Abnormality of midbrain morphology (HP:0002418) | 3.68755143 |
5 | True hermaphroditism (HP:0010459) | 3.66553261 |
6 | Congenital stationary night blindness (HP:0007642) | 3.58681652 |
7 | Nephronophthisis (HP:0000090) | 3.19442591 |
8 | Pendular nystagmus (HP:0012043) | 2.89854024 |
9 | Type II lissencephaly (HP:0007260) | 2.88293526 |
10 | Medial flaring of the eyebrow (HP:0010747) | 2.83092474 |
11 | Chronic hepatic failure (HP:0100626) | 2.80465992 |
12 | Abnormality of the renal medulla (HP:0100957) | 2.77922396 |
13 | Abnormality of the renal cortex (HP:0011035) | 2.72968667 |
14 | Hyperventilation (HP:0002883) | 2.72160194 |
15 | Abnormality of the labia minora (HP:0012880) | 2.66148388 |
16 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.63153923 |
17 | Septo-optic dysplasia (HP:0100842) | 2.62535081 |
18 | Abolished electroretinogram (ERG) (HP:0000550) | 2.61321048 |
19 | Optic nerve hypoplasia (HP:0000609) | 2.60168507 |
20 | Acute necrotizing encephalopathy (HP:0006965) | 2.54333186 |
21 | Cystic liver disease (HP:0006706) | 2.52330807 |
22 | Colon cancer (HP:0003003) | 2.52061068 |
23 | Methylmalonic acidemia (HP:0002912) | 2.48548605 |
24 | Mitochondrial inheritance (HP:0001427) | 2.36542949 |
25 | Increased CSF lactate (HP:0002490) | 2.36090012 |
26 | Sclerocornea (HP:0000647) | 2.33760288 |
27 | Intestinal atresia (HP:0011100) | 2.33135375 |
28 | Gaze-evoked nystagmus (HP:0000640) | 2.26788923 |
29 | Progressive macrocephaly (HP:0004481) | 2.25439338 |
30 | Acute encephalopathy (HP:0006846) | 2.24103144 |
31 | Gait imbalance (HP:0002141) | 2.23006933 |
32 | Bilateral microphthalmos (HP:0007633) | 2.21646532 |
33 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.20447286 |
34 | Abnormality of alanine metabolism (HP:0010916) | 2.20447286 |
35 | Hyperalaninemia (HP:0003348) | 2.20447286 |
36 | Methylmalonic aciduria (HP:0012120) | 2.19904973 |
37 | Genital tract atresia (HP:0001827) | 2.18937872 |
38 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.18720771 |
39 | Vaginal atresia (HP:0000148) | 2.18540332 |
40 | Anencephaly (HP:0002323) | 2.18423077 |
41 | Congenital primary aphakia (HP:0007707) | 2.18166134 |
42 | Abnormal biliary tract physiology (HP:0012439) | 2.12684834 |
43 | Bile duct proliferation (HP:0001408) | 2.12684834 |
44 | Nephrogenic diabetes insipidus (HP:0009806) | 2.12311076 |
45 | Gastrointestinal atresia (HP:0002589) | 2.12262139 |
46 | Tubular atrophy (HP:0000092) | 2.11150732 |
47 | Renal cortical cysts (HP:0000803) | 2.10766068 |
48 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.10756253 |
49 | Inability to walk (HP:0002540) | 2.10594961 |
50 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.10061304 |
51 | Esophageal atresia (HP:0002032) | 2.08976388 |
52 | Attenuation of retinal blood vessels (HP:0007843) | 2.08788833 |
53 | Progressive cerebellar ataxia (HP:0002073) | 2.08002151 |
54 | Cerebellar dysplasia (HP:0007033) | 2.04953503 |
55 | Hyperglycinuria (HP:0003108) | 2.03867858 |
56 | Broad-based gait (HP:0002136) | 2.03156528 |
57 | Abnormality of the ileum (HP:0001549) | 2.01050777 |
58 | Abnormality of the pons (HP:0007361) | 1.99611883 |
59 | Progressive inability to walk (HP:0002505) | 1.99389367 |
60 | Meckel diverticulum (HP:0002245) | 1.97556520 |
61 | Male pseudohermaphroditism (HP:0000037) | 1.97489600 |
62 | Hypoplasia of the pons (HP:0012110) | 1.96938860 |
63 | Hepatocellular necrosis (HP:0001404) | 1.96327882 |
64 | Increased corneal curvature (HP:0100692) | 1.95225165 |
65 | Keratoconus (HP:0000563) | 1.95225165 |
66 | Large for gestational age (HP:0001520) | 1.94416417 |
67 | Lissencephaly (HP:0001339) | 1.92334291 |
68 | Abnormality of macular pigmentation (HP:0008002) | 1.91803753 |
69 | Polydipsia (HP:0001959) | 1.90776118 |
70 | Abnormal drinking behavior (HP:0030082) | 1.90776118 |
71 | Furrowed tongue (HP:0000221) | 1.89756465 |
72 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.88479388 |
73 | Dialeptic seizures (HP:0011146) | 1.88377218 |
74 | Congenital, generalized hypertrichosis (HP:0004540) | 1.86582236 |
75 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.86270616 |
76 | Oligodactyly (hands) (HP:0001180) | 1.85387893 |
77 | Hepatic necrosis (HP:0002605) | 1.84735809 |
78 | Stomach cancer (HP:0012126) | 1.82253902 |
79 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.81777608 |
80 | Congenital hepatic fibrosis (HP:0002612) | 1.79992971 |
81 | Focal seizures (HP:0007359) | 1.79619472 |
82 | Hypomagnesemia (HP:0002917) | 1.77826255 |
83 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.77262988 |
84 | Hypoplasia of the fovea (HP:0007750) | 1.77262988 |
85 | Abnormality of the renal collecting system (HP:0004742) | 1.71899998 |
86 | Optic disc pallor (HP:0000543) | 1.71790046 |
87 | Genetic anticipation (HP:0003743) | 1.71211541 |
88 | Focal motor seizures (HP:0011153) | 1.70538377 |
89 | Dandy-Walker malformation (HP:0001305) | 1.70372125 |
90 | Hypothermia (HP:0002045) | 1.70276430 |
91 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.69530106 |
92 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.68803358 |
93 | Hyperglycinemia (HP:0002154) | 1.66743138 |
94 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.66680931 |
95 | Absent/shortened dynein arms (HP:0200106) | 1.66680931 |
96 | Stenosis of the external auditory canal (HP:0000402) | 1.66462496 |
97 | Febrile seizures (HP:0002373) | 1.66396643 |
98 | Anophthalmia (HP:0000528) | 1.66313462 |
99 | Lipid accumulation in hepatocytes (HP:0006561) | 1.66057677 |
100 | Absent septum pellucidum (HP:0001331) | 1.65573528 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 4.74596475 |
2 | WNK3 | 3.37128166 |
3 | NUAK1 | 2.81114770 |
4 | ZAK | 2.62313377 |
5 | MAP4K2 | 2.56285588 |
6 | ADRBK2 | 2.53322976 |
7 | CASK | 2.47083632 |
8 | BMPR1B | 2.44221002 |
9 | TLK1 | 2.44075887 |
10 | GRK1 | 2.37036572 |
11 | TNIK | 2.28213539 |
12 | PINK1 | 2.19855314 |
13 | ACVR1B | 2.10713990 |
14 | VRK2 | 1.83267651 |
15 | OXSR1 | 1.78379387 |
16 | WNK4 | 1.73700877 |
17 | MAP3K4 | 1.70543334 |
18 | CDK19 | 1.57172834 |
19 | INSRR | 1.53593838 |
20 | FGFR2 | 1.48295218 |
21 | DYRK2 | 1.42864398 |
22 | MAPK13 | 1.41342952 |
23 | MAP2K6 | 1.36128618 |
24 | PNCK | 1.33077702 |
25 | PAK3 | 1.29227555 |
26 | CDC7 | 1.28364203 |
27 | TXK | 1.26770012 |
28 | MST4 | 1.19611466 |
29 | TRIM28 | 1.17009790 |
30 | VRK1 | 1.14795712 |
31 | MKNK2 | 1.14744768 |
32 | BRSK2 | 1.14348055 |
33 | PLK3 | 1.13949267 |
34 | TAF1 | 1.11222741 |
35 | PLK4 | 1.08947855 |
36 | NME1 | 1.08628422 |
37 | TAOK3 | 1.02502034 |
38 | PRKCE | 1.02052746 |
39 | PRKCG | 1.00382542 |
40 | PASK | 0.97401787 |
41 | STK38L | 0.96770817 |
42 | PLK2 | 0.94615962 |
43 | STK39 | 0.89912323 |
44 | MAP2K7 | 0.89582779 |
45 | BCR | 0.88997353 |
46 | TIE1 | 0.88696818 |
47 | STK16 | 0.88631929 |
48 | CSNK1G1 | 0.87788249 |
49 | ADRBK1 | 0.87313027 |
50 | TGFBR1 | 0.86687732 |
51 | DAPK2 | 0.85057368 |
52 | TSSK6 | 0.80588503 |
53 | WEE1 | 0.79791118 |
54 | DYRK3 | 0.79374835 |
55 | NLK | 0.79134003 |
56 | CSNK1G2 | 0.78365808 |
57 | MARK1 | 0.75563853 |
58 | NEK2 | 0.69698833 |
59 | NTRK3 | 0.69593765 |
60 | MKNK1 | 0.67451240 |
61 | PHKG1 | 0.65837452 |
62 | PHKG2 | 0.65837452 |
63 | PLK1 | 0.65672046 |
64 | MUSK | 0.62171612 |
65 | TEC | 0.62025837 |
66 | TAOK2 | 0.61172657 |
67 | PIK3CA | 0.59819560 |
68 | OBSCN | 0.59805666 |
69 | CSNK1G3 | 0.59577225 |
70 | BUB1 | 0.57062396 |
71 | TTK | 0.56304260 |
72 | PKN1 | 0.54089698 |
73 | CHEK2 | 0.53934042 |
74 | MAPKAPK5 | 0.52275138 |
75 | EPHA4 | 0.50612254 |
76 | STK3 | 0.50556678 |
77 | BCKDK | 0.49865480 |
78 | NTRK2 | 0.49750493 |
79 | AKT3 | 0.48250438 |
80 | CAMK2A | 0.47974261 |
81 | CSNK1A1 | 0.47003482 |
82 | STK11 | 0.46555573 |
83 | ATR | 0.46109869 |
84 | ATM | 0.45714907 |
85 | PRKCQ | 0.44602185 |
86 | PRKACA | 0.44075401 |
87 | PBK | 0.41373827 |
88 | PRKACB | 0.39528671 |
89 | SIK2 | 0.39254298 |
90 | PDK2 | 0.38182242 |
91 | RPS6KA5 | 0.37618536 |
92 | CSNK1A1L | 0.37455092 |
93 | PRKG1 | 0.37217243 |
94 | FGFR1 | 0.35000022 |
95 | EIF2AK3 | 0.34909626 |
96 | ITK | 0.34866907 |
97 | DYRK1A | 0.34166672 |
98 | PRKCI | 0.33033506 |
99 | GRK7 | 0.33000439 |
100 | PRKCA | 0.32364123 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.09030182 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 2.50439193 |
3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.40942149 |
4 | Phototransduction_Homo sapiens_hsa04744 | 2.36049274 |
5 | Protein export_Homo sapiens_hsa03060 | 2.31439567 |
6 | Homologous recombination_Homo sapiens_hsa03440 | 2.11722136 |
7 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.10517210 |
8 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.10382847 |
9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.08446383 |
10 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.07013363 |
11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.03619831 |
12 | RNA polymerase_Homo sapiens_hsa03020 | 2.03060036 |
13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.98603771 |
14 | Nicotine addiction_Homo sapiens_hsa05033 | 1.96742794 |
15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.93575105 |
16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.92657422 |
17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.87119403 |
18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.75988822 |
19 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.75462180 |
20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.74808116 |
21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.68895108 |
22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.68733563 |
23 | Ribosome_Homo sapiens_hsa03010 | 1.62437636 |
24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.60233492 |
25 | Alzheimers disease_Homo sapiens_hsa05010 | 1.58720578 |
26 | RNA degradation_Homo sapiens_hsa03018 | 1.55405129 |
27 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.46646940 |
28 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.45011291 |
29 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.35488131 |
30 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.33020510 |
31 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.30658332 |
32 | Taste transduction_Homo sapiens_hsa04742 | 1.28617288 |
33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.28421779 |
34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.28134718 |
35 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.27443335 |
36 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.24146591 |
37 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.22686864 |
38 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.19148261 |
39 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.16595254 |
40 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.14802382 |
41 | Retinol metabolism_Homo sapiens_hsa00830 | 1.13339735 |
42 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.12300516 |
43 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.11332439 |
44 | Proteasome_Homo sapiens_hsa03050 | 1.11192538 |
45 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.09482750 |
46 | Peroxisome_Homo sapiens_hsa04146 | 1.07624634 |
47 | Olfactory transduction_Homo sapiens_hsa04740 | 1.06763239 |
48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.00865082 |
49 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.00490605 |
50 | Mismatch repair_Homo sapiens_hsa03430 | 0.97883291 |
51 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.95048137 |
52 | Morphine addiction_Homo sapiens_hsa05032 | 0.93985959 |
53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.90270351 |
54 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.90177701 |
55 | Purine metabolism_Homo sapiens_hsa00230 | 0.88240189 |
56 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.87931217 |
57 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.86451899 |
58 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.83028313 |
59 | GABAergic synapse_Homo sapiens_hsa04727 | 0.81690346 |
60 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.81240442 |
61 | ABC transporters_Homo sapiens_hsa02010 | 0.80191316 |
62 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.79116457 |
63 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.76712662 |
64 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74837070 |
65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.74120916 |
66 | Insulin secretion_Homo sapiens_hsa04911 | 0.73495372 |
67 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.73363690 |
68 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.73290505 |
69 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.72708870 |
70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71778457 |
71 | Circadian rhythm_Homo sapiens_hsa04710 | 0.69665937 |
72 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68776916 |
73 | Circadian entrainment_Homo sapiens_hsa04713 | 0.68163293 |
74 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.65455194 |
75 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.65177925 |
76 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.63658606 |
77 | RNA transport_Homo sapiens_hsa03013 | 0.61579716 |
78 | Mineral absorption_Homo sapiens_hsa04978 | 0.60918279 |
79 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.60819760 |
80 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.58307148 |
81 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.54937495 |
82 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.53892781 |
83 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.53656056 |
84 | Histidine metabolism_Homo sapiens_hsa00340 | 0.53328451 |
85 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.53128559 |
86 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.52536109 |
87 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.51714734 |
88 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.50283362 |
89 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48736598 |
90 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.48377326 |
91 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.48040810 |
92 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46752781 |
93 | Salivary secretion_Homo sapiens_hsa04970 | 0.43952174 |
94 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.42039367 |
95 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.41500668 |
96 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.41442860 |
97 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.39367308 |
98 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.39078796 |
99 | Cocaine addiction_Homo sapiens_hsa05030 | 0.37199482 |
100 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.36444122 |