ZNF209P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cardiac right ventricle morphogenesis (GO:0003215)5.85129359
2positive regulation of male gonad development (GO:2000020)5.10726892
3regulation of hexokinase activity (GO:1903299)4.92895132
4regulation of glucokinase activity (GO:0033131)4.92895132
5negative regulation of metanephros development (GO:0072217)4.85454171
6regulation of male gonad development (GO:2000018)4.79257842
7cobalamin metabolic process (GO:0009235)4.49689015
8negative regulation of acute inflammatory response (GO:0002674)4.43422792
9positive regulation of actin filament depolymerization (GO:0030836)4.37650020
10vitamin transport (GO:0051180)4.29502909
11transepithelial transport (GO:0070633)4.21456497
12regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033393.91570645
13regulation of protein glycosylation (GO:0060049)3.88624255
14fucose catabolic process (GO:0019317)3.77296566
15L-fucose metabolic process (GO:0042354)3.77296566
16L-fucose catabolic process (GO:0042355)3.77296566
17regulation of gonadotropin secretion (GO:0032276)3.77133562
18preassembly of GPI anchor in ER membrane (GO:0016254)3.71787331
19heart field specification (GO:0003128)3.66933711
20secondary heart field specification (GO:0003139)3.66933711
21platelet dense granule organization (GO:0060155)3.46296864
22nitric oxide mediated signal transduction (GO:0007263)3.45015438
23cellular response to follicle-stimulating hormone stimulus (GO:0071372)3.43406072
24cardiac ventricle morphogenesis (GO:0003208)3.43060407
25cellular response to gonadotropin stimulus (GO:0071371)3.41436755
26pancreas development (GO:0031016)3.39516723
27base-excision repair, AP site formation (GO:0006285)3.38676076
28female gonad development (GO:0008585)3.30836158
29Leydig cell differentiation (GO:0033327)3.27194817
30positive regulation of glycolytic process (GO:0045821)3.21862735
31regulation of female gonad development (GO:2000194)3.20138412
32negative regulation of macrophage differentiation (GO:0045650)3.19217537
33regulation of type B pancreatic cell apoptotic process (GO:2000674)3.13779349
34GPI anchor metabolic process (GO:0006505)3.11958956
35negative regulation of neurological system process (GO:0031645)3.09752727
36regulation of cell proliferation involved in kidney development (GO:1901722)3.09430524
37atrial septum morphogenesis (GO:0060413)3.05732114
38epithelial cell differentiation involved in kidney development (GO:0035850)3.05275485
39negative regulation of kidney development (GO:0090185)3.04983545
40mesenchymal to epithelial transition (GO:0060231)3.03203232
41negative regulation of mesenchymal cell apoptotic process (GO:2001054)3.01357801
42response to parathyroid hormone (GO:0071107)3.00317423
43otic vesicle formation (GO:0030916)2.98118985
44DNA deamination (GO:0045006)2.97689787
45GPI anchor biosynthetic process (GO:0006506)2.96650180
46N-terminal protein amino acid acetylation (GO:0006474)2.96531379
47DNA damage response, detection of DNA damage (GO:0042769)2.94750576
48SMAD protein signal transduction (GO:0060395)2.92910421
49glomerulus development (GO:0032835)2.90632551
50columnar/cuboidal epithelial cell differentiation (GO:0002065)2.90238056
51short-term memory (GO:0007614)2.89714051
52negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.88506684
53negative regulation of protein oligomerization (GO:0032460)2.87344926
54oxidative demethylation (GO:0070989)2.87058428
55response to follicle-stimulating hormone (GO:0032354)2.86590103
56chaperone-mediated protein complex assembly (GO:0051131)2.85652751
57regulation of cardioblast proliferation (GO:0003264)2.85516954
58regulation of secondary heart field cardioblast proliferation (GO:0003266)2.85516954
59cholesterol biosynthetic process (GO:0006695)2.84712858
60pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.81208731
61cardiac chamber morphogenesis (GO:0003206)2.80566465
62epithelial cell fate commitment (GO:0072148)2.80390533
63negative regulation of complement activation (GO:0045916)2.80101964
64somite rostral/caudal axis specification (GO:0032525)2.76703940
65fusion of sperm to egg plasma membrane (GO:0007342)2.75787105
66outflow tract septum morphogenesis (GO:0003148)2.74779482
67protein-chromophore linkage (GO:0018298)2.72080456
68negative regulation of glycoprotein metabolic process (GO:1903019)2.70554476
69regulation of glomerulus development (GO:0090192)2.70126579
70endocrine pancreas development (GO:0031018)2.69804676
71response to gonadotropin (GO:0034698)2.68761096
72sperm capacitation (GO:0048240)2.67768228
73arginine catabolic process (GO:0006527)2.66497801
74protein-cofactor linkage (GO:0018065)2.64035213
75cornea development in camera-type eye (GO:0061303)2.63795439
76sterol biosynthetic process (GO:0016126)2.62475219
77endoderm formation (GO:0001706)2.62064310
78specification of organ identity (GO:0010092)2.62055593
79short-chain fatty acid metabolic process (GO:0046459)2.60517170
80branched-chain amino acid catabolic process (GO:0009083)2.59158319
81pituitary gland development (GO:0021983)2.58074712
82secondary metabolite biosynthetic process (GO:0044550)2.57321242
83retinal ganglion cell axon guidance (GO:0031290)2.56551757
84histone H4-K12 acetylation (GO:0043983)2.56242634
85positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.55587211
86eye photoreceptor cell differentiation (GO:0001754)2.54437794
87photoreceptor cell differentiation (GO:0046530)2.54437794
88transcytosis (GO:0045056)2.54011985
89sex determination (GO:0007530)2.53691492
90embryonic axis specification (GO:0000578)2.53667778
91C-terminal protein lipidation (GO:0006501)2.52755658
92seminiferous tubule development (GO:0072520)2.48895406
93positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.48583602
94response to misfolded protein (GO:0051788)2.47966030
95kidney morphogenesis (GO:0060993)2.47802699
96smooth muscle tissue development (GO:0048745)2.47733879
97positive regulation of heart growth (GO:0060421)2.44306836
98positive regulation of insulin secretion (GO:0032024)2.44128824
99artery smooth muscle contraction (GO:0014824)2.44083725
100regulation of glycoprotein metabolic process (GO:1903018)2.43888479

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GLI1_17442700_ChIP-ChIP_MESCs_Mouse4.86308460
2GBX2_23144817_ChIP-Seq_PC3_Human3.47801834
3ZNF274_21170338_ChIP-Seq_K562_Hela3.35325297
4IGF1R_20145208_ChIP-Seq_DFB_Human3.32651998
5VDR_22108803_ChIP-Seq_LS180_Human2.83638957
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.64152395
7KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.55547319
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.43307082
9POU3F2_20337985_ChIP-ChIP_501MEL_Human2.42984069
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.41869007
11FUS_26573619_Chip-Seq_HEK293_Human2.36062515
12TAF15_26573619_Chip-Seq_HEK293_Human2.11386762
13P300_19829295_ChIP-Seq_ESCs_Human2.10375276
14AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.06598315
15EWS_26573619_Chip-Seq_HEK293_Human2.04002765
16CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02865471
17BCAT_22108803_ChIP-Seq_LS180_Human1.97647970
18CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.92921841
19PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.88652607
20PIAS1_25552417_ChIP-Seq_VCAP_Human1.73930957
21IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.61801338
22CBP_20019798_ChIP-Seq_JUKART_Human1.61801338
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.61059964
24SALL1_21062744_ChIP-ChIP_HESCs_Human1.60691582
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.59510677
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.58264039
27UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.57532661
28ARNT_22903824_ChIP-Seq_MCF-7_Human1.54399776
29AHR_22903824_ChIP-Seq_MCF-7_Human1.54308730
30TOP2B_26459242_ChIP-Seq_MCF-7_Human1.52256083
31SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.49006600
32BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48824389
33TP53_22573176_ChIP-Seq_HFKS_Human1.47642125
34SOX2_19829295_ChIP-Seq_ESCs_Human1.47060990
35NANOG_19829295_ChIP-Seq_ESCs_Human1.47060990
36SMAD4_21799915_ChIP-Seq_A2780_Human1.46412196
37PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.45550951
38ER_23166858_ChIP-Seq_MCF-7_Human1.45439392
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.44178771
40CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41203923
41NR3C1_21868756_ChIP-Seq_MCF10A_Human1.40685002
42CTBP1_25329375_ChIP-Seq_LNCAP_Human1.40534452
43ESR1_21235772_ChIP-Seq_MCF-7_Human1.39737564
44SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.39319538
45TCF4_23295773_ChIP-Seq_U87_Human1.36145169
46FLI1_27457419_Chip-Seq_LIVER_Mouse1.35883956
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.35485129
48EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.35344374
49FOXA1_25329375_ChIP-Seq_VCAP_Human1.34459232
50FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34459232
51FOXA1_21572438_ChIP-Seq_LNCaP_Human1.33067939
52EZH2_27294783_Chip-Seq_NPCs_Mouse1.32033252
53AUTS2_25519132_ChIP-Seq_293T-REX_Human1.31465092
54MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.31328536
55SUZ12_27294783_Chip-Seq_NPCs_Mouse1.28664510
56AR_20517297_ChIP-Seq_VCAP_Human1.27542812
57RNF2_27304074_Chip-Seq_NSC_Mouse1.27268418
58POU5F1_16153702_ChIP-ChIP_HESCs_Human1.26383772
59PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26190480
60BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.26177588
61NFE2_27457419_Chip-Seq_LIVER_Mouse1.25314584
62OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25015975
63SMAD3_21741376_ChIP-Seq_EPCs_Human1.24088860
64NANOG_18555785_Chip-Seq_ESCs_Mouse1.23453848
65KLF5_20875108_ChIP-Seq_MESCs_Mouse1.22927944
66EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.20578936
67ELK1_19687146_ChIP-ChIP_HELA_Human1.20481098
68P53_22387025_ChIP-Seq_ESCs_Mouse1.20052999
69FOXM1_26456572_ChIP-Seq_MCF-7_Human1.19771790
70SMAD4_21741376_ChIP-Seq_EPCs_Human1.18705995
71GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.17243536
72NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.16428566
73RUNX2_22187159_ChIP-Seq_PCA_Human1.16105684
74TCF4_22108803_ChIP-Seq_LS180_Human1.16062298
75STAT3_23295773_ChIP-Seq_U87_Human1.15806266
76FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.11571731
77MYC_18940864_ChIP-ChIP_HL60_Human1.10507543
78AR_25329375_ChIP-Seq_VCAP_Human1.09958790
79PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08977072
80TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.08880576
81MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.08762475
82RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.08537459
83HTT_18923047_ChIP-ChIP_STHdh_Human1.07596531
84CDX2_22108803_ChIP-Seq_LS180_Human1.06783889
85ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05919588
86EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.05692176
87POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04594142
88TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04594142
89CBX2_27304074_Chip-Seq_ESCs_Mouse1.04267696
90GABP_17652178_ChIP-ChIP_JURKAT_Human1.04047015
91STAT3_18555785_Chip-Seq_ESCs_Mouse1.03559076
92TCF4_18268006_ChIP-ChIP_LS174T_Human1.03454183
93FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.02049346
94EST1_17652178_ChIP-ChIP_JURKAT_Human1.01929947
95NCOR_22424771_ChIP-Seq_293T_Human1.01771708
96EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01514617
97MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01179196
98SRF_21415370_ChIP-Seq_HL-1_Mouse1.01119446
99HOXB7_26014856_ChIP-Seq_BT474_Human1.01051720
100CMYC_18555785_Chip-Seq_ESCs_Mouse0.97623230

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002163_abnormal_gland_morphology4.99302792
2MP0005379_endocrine/exocrine_gland_phen3.75411946
3MP0003123_paternal_imprinting3.57356448
4MP0008995_early_reproductive_senescence3.42377266
5MP0005220_abnormal_exocrine_pancreas3.14862342
6MP0002876_abnormal_thyroid_physiology3.04213888
7MP0008877_abnormal_DNA_methylation2.89420908
8MP0003121_genomic_imprinting2.89016011
9MP0005646_abnormal_pituitary_gland2.79305015
10MP0003195_calcinosis2.68750566
11MP0000516_abnormal_urinary_system2.49485859
12MP0005367_renal/urinary_system_phenotyp2.49485859
13MP0003787_abnormal_imprinting2.44316693
14MP0002132_abnormal_respiratory_system2.33039781
15MP0005410_abnormal_fertilization2.32363789
16MP0005645_abnormal_hypothalamus_physiol2.19431021
17MP0002277_abnormal_respiratory_mucosa2.18448985
18MP0003122_maternal_imprinting2.05515407
19MP0003283_abnormal_digestive_organ1.95013075
20MP0009780_abnormal_chondrocyte_physiolo1.94901555
21MP0008872_abnormal_physiological_respon1.93015308
22MP0000537_abnormal_urethra_morphology1.87857145
23MP0005389_reproductive_system_phenotype1.86031182
24MP0003880_abnormal_central_pattern1.85648673
25MP0001919_abnormal_reproductive_system1.84512136
26MP0008875_abnormal_xenobiotic_pharmacok1.82315484
27MP0006072_abnormal_retinal_apoptosis1.80351842
28MP0003950_abnormal_plasma_membrane1.79300362
29MP0010386_abnormal_urinary_bladder1.75544696
30MP0000427_abnormal_hair_cycle1.65054653
31MP0000631_abnormal_neuroendocrine_gland1.53550183
32MP0004133_heterotaxia1.48803266
33MP0003300_gastrointestinal_ulcer1.47317718
34MP0002928_abnormal_bile_duct1.47274931
35MP0002160_abnormal_reproductive_system1.45104832
36MP0003786_premature_aging1.44308537
37MP0003011_delayed_dark_adaptation1.39887892
38MP0000639_abnormal_adrenal_gland1.38784196
39MP0000462_abnormal_digestive_system1.38385972
40MP0005551_abnormal_eye_electrophysiolog1.37801675
41MP0000538_abnormal_urinary_bladder1.34002688
42MP0003943_abnormal_hepatobiliary_system1.33785863
43MP0006276_abnormal_autonomic_nervous1.30806095
44MP0003119_abnormal_digestive_system1.20811022
45MP0001984_abnormal_olfaction1.18756409
46MP0006292_abnormal_olfactory_placode1.16143296
47MP0001188_hyperpigmentation1.13485378
48MP0001501_abnormal_sleep_pattern1.12392245
49MP0002751_abnormal_autonomic_nervous1.08871949
50MP0002653_abnormal_ependyma_morphology1.06252358
51MP0001661_extended_life_span1.06015045
52MP0000613_abnormal_salivary_gland1.04969321
53MP0003656_abnormal_erythrocyte_physiolo1.04530741
54MP0003890_abnormal_embryonic-extraembry1.00900215
55MP0009697_abnormal_copulation0.99446540
56MP0005395_other_phenotype0.99187665
57MP0003315_abnormal_perineum_morphology0.98747737
58MP0001177_atelectasis0.98415048
59MP0002127_abnormal_cardiovascular_syste0.95592042
60MP0001764_abnormal_homeostasis0.95324441
61MP0001944_abnormal_pancreas_morphology0.95222878
62MP0001119_abnormal_female_reproductive0.93778286
63MP0004043_abnormal_pH_regulation0.90448050
64MP0009046_muscle_twitch0.89076757
65MP0009745_abnormal_behavioral_response0.89043064
66MP0002089_abnormal_postnatal_growth/wei0.88592009
67MP0004270_analgesia0.88410971
68MP0001270_distended_abdomen0.87143702
69MP0005253_abnormal_eye_physiology0.84035982
70MP0002837_dystrophic_cardiac_calcinosis0.82059465
71MP0003936_abnormal_reproductive_system0.82028653
72MP0002272_abnormal_nervous_system0.81051621
73MP0002210_abnormal_sex_determination0.78887666
74MP0002168_other_aberrant_phenotype0.78796154
75MP0004085_abnormal_heartbeat0.76769707
76MP0001929_abnormal_gametogenesis0.76765309
77MP0001145_abnormal_male_reproductive0.75000599
78MP0000653_abnormal_sex_gland0.74993328
79MP0001502_abnormal_circadian_rhythm0.74557918
80MP0004019_abnormal_vitamin_homeostasis0.74420362
81MP0002138_abnormal_hepatobiliary_system0.74221171
82MP0005386_behavior/neurological_phenoty0.73303131
83MP0004924_abnormal_behavior0.73303131
84MP0003698_abnormal_male_reproductive0.71560424
85MP0001664_abnormal_digestion0.70221993
86MP0004084_abnormal_cardiac_muscle0.69214526
87MP0005636_abnormal_mineral_homeostasis0.68992528
88MP0005075_abnormal_melanosome_morpholog0.67624745
89MP0000383_abnormal_hair_follicle0.63954031
90MP0001765_abnormal_ion_homeostasis0.62374570
91MP0000681_abnormal_thyroid_gland0.62094516
92MP0002938_white_spotting0.61869334
93MP0004381_abnormal_hair_follicle0.61326530
94MP0002638_abnormal_pupillary_reflex0.61220562
95MP0004142_abnormal_muscle_tone0.58776503
96MP0001529_abnormal_vocalization0.58762777
97MP0002233_abnormal_nose_morphology0.58502740
98MP0002557_abnormal_social/conspecific_i0.58300399
99MP0005195_abnormal_posterior_eye0.57945036
100MP0004782_abnormal_surfactant_physiolog0.56762759

Predicted human phenotypes

RankGene SetZ-score
1Gonadal dysgenesis (HP:0000133)4.70055417
2Male infertility (HP:0003251)4.67578927
3Testicular neoplasm (HP:0010788)3.83830613
4Abnormal pancreas size (HP:0012094)3.76367919
5Type II lissencephaly (HP:0007260)3.74089948
6True hermaphroditism (HP:0010459)3.62686686
7Large for gestational age (HP:0001520)3.61634016
83-Methylglutaconic aciduria (HP:0003535)3.45072714
9Renal cortical cysts (HP:0000803)3.42389569
10Azoospermia (HP:0000027)3.32560652
11Hypoplastic left heart (HP:0004383)3.22786986
12Retinal dysplasia (HP:0007973)3.17960876
13Male pseudohermaphroditism (HP:0000037)3.14083149
14Tongue fasciculations (HP:0001308)3.11004165
15Hypomagnesemia (HP:0002917)3.01665928
16Abnormality of the renal cortex (HP:0011035)2.91503084
17Abnormality of the pons (HP:0007361)2.89512082
18Rectal prolapse (HP:0002035)2.85149722
19Exocrine pancreatic insufficiency (HP:0001738)2.83869556
20Transposition of the great arteries (HP:0001669)2.70224052
21Abnormal connection of the cardiac segments (HP:0011545)2.70224052
22Abnormal ventriculo-arterial connection (HP:0011563)2.70224052
23Ileus (HP:0002595)2.66776378
24Renal salt wasting (HP:0000127)2.61635082
25Duplicated collecting system (HP:0000081)2.60452223
26Dry hair (HP:0011359)2.57916619
27Sex reversal (HP:0012245)2.57234413
28Abnormal sex determination (HP:0012244)2.57234413
29Muscle fibrillation (HP:0010546)2.56547225
30Medial flaring of the eyebrow (HP:0010747)2.54190016
31Stridor (HP:0010307)2.52969349
32Pancreatic cysts (HP:0001737)2.49947374
33Degeneration of the lateral corticospinal tracts (HP:0002314)2.48924884
34Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.48924884
35Hypoplastic heart (HP:0001961)2.44876216
36Irregular vertebral endplates (HP:0003301)2.44840166
37Abnormality of the renal collecting system (HP:0004742)2.43984575
38Abnormal spermatogenesis (HP:0008669)2.43572043
39Abolished electroretinogram (ERG) (HP:0000550)2.42928073
40Facial diplegia (HP:0001349)2.41674103
41Methylmalonic acidemia (HP:0002912)2.37962293
42Tubulointerstitial nephritis (HP:0001970)2.35618703
43Hypsarrhythmia (HP:0002521)2.34943494
44Widely spaced teeth (HP:0000687)2.31984317
45Unilateral renal agenesis (HP:0000122)2.30033734
46Gait imbalance (HP:0002141)2.27838980
47Abnormality of the pancreatic islet cells (HP:0006476)2.26718427
48Abnormality of endocrine pancreas physiology (HP:0012093)2.26718427
49EEG with generalized epileptiform discharges (HP:0011198)2.25149177
50Abnormality of midbrain morphology (HP:0002418)2.24551752
51Molar tooth sign on MRI (HP:0002419)2.24551752
52Congenital primary aphakia (HP:0007707)2.23927583
53Poor suck (HP:0002033)2.23645124
54Mesangial abnormality (HP:0001966)2.22817621
55Abnormality of magnesium homeostasis (HP:0004921)2.22713972
56Atrioventricular canal defect (HP:0006695)2.20426448
57Epileptiform EEG discharges (HP:0011182)2.20001190
58Ankle clonus (HP:0011448)2.16679320
59Abnormality of the labia minora (HP:0012880)2.14494842
60Cortical visual impairment (HP:0100704)2.10207851
61Abnormality of the right ventricle (HP:0001707)2.07258350
62Degeneration of anterior horn cells (HP:0002398)2.06541224
63Abnormality of the anterior horn cell (HP:0006802)2.06541224
64Nephrogenic diabetes insipidus (HP:0009806)2.06146599
65Abnormality of chloride homeostasis (HP:0011422)2.05477138
66Abnormality of the vertebral endplates (HP:0005106)2.04197774
67Barrel-shaped chest (HP:0001552)2.03930742
68Abnormality of the corticospinal tract (HP:0002492)2.00873932
69Dyskinesia (HP:0100660)2.00312805
70Diaphragmatic weakness (HP:0009113)2.00149719
71Epileptic encephalopathy (HP:0200134)1.99317736
72Pancreatic fibrosis (HP:0100732)1.94733017
73Inability to walk (HP:0002540)1.93348236
74Tachypnea (HP:0002789)1.92078461
75Narrow forehead (HP:0000341)1.90949599
76Complete atrioventricular canal defect (HP:0001674)1.90712421
77Cystic liver disease (HP:0006706)1.89334671
78Abnormal biliary tract morphology (HP:0012440)1.89210991
79Chronic hepatic failure (HP:0100626)1.88334564
80Absent eyebrow (HP:0002223)1.87722217
81Adrenal hypoplasia (HP:0000835)1.85522048
82Lissencephaly (HP:0001339)1.84937230
83Ketoacidosis (HP:0001993)1.84179670
84Hypothermia (HP:0002045)1.84107226
85Clumsiness (HP:0002312)1.82569993
86Abnormality of the vocal cords (HP:0008777)1.78085450
87Scrotal hypoplasia (HP:0000046)1.75736363
88Infertility (HP:0000789)1.72544049
89Anomalous pulmonary venous return (HP:0010772)1.71382282
90Curly hair (HP:0002212)1.71317164
91Megaloblastic anemia (HP:0001889)1.70825391
92Hyperglycinuria (HP:0003108)1.69200684
93Neoplasm of the adrenal cortex (HP:0100641)1.69160818
94Esotropia (HP:0000565)1.68910148
95Alopecia of scalp (HP:0002293)1.68859450
96Absent septum pellucidum (HP:0001331)1.66914294
97Diminished movement (HP:0002374)1.66909386
98Ureteral duplication (HP:0000073)1.66820595
99Febrile seizures (HP:0002373)1.66620383
100Vaginal atresia (HP:0000148)1.65645588

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LMTK28.56368263
2MAP4K25.10248779
3TNIK3.48249737
4FRK3.32540444
5EIF2AK32.89190514
6MST42.68720441
7WNK32.30876153
8PRKG22.25202651
9PASK2.21408969
10DAPK22.17592770
11PINK12.15671386
12AKT31.91034753
13BCR1.83969919
14CDK191.71469756
15TRIM281.69846856
16PAK31.69468603
17NUAK11.63478878
18OXSR11.39649806
19MARK11.31479220
20MAPK131.29882041
21PHKG11.26108561
22PHKG21.26108561
23STK31.20071021
24FGFR21.15578406
25BRD41.14504736
26ZAK1.14212517
27PLK31.14179124
28ERBB31.09490714
29TAOK31.07195503
30NEK11.03127114
31SIK31.01584472
32CSNK1G21.00341172
33PRKCE0.99556529
34CSNK1G30.96711169
35BRSK20.96513231
36ACVR1B0.95636059
37CAMKK20.91542650
38STK390.86711764
39CSNK1G10.80208270
40TNK20.79930403
41CSNK1A1L0.79828564
42DAPK10.76692965
43STK160.73728360
44MAP3K40.71265643
45NLK0.71013188
46GRK10.70851102
47FER0.69580028
48INSRR0.68460755
49SGK20.66446793
50VRK10.65764474
51WNK40.64050718
52PRKAA10.64041000
53PRKG10.63927175
54PAK60.62818952
55ROCK10.61079904
56MAP2K70.60510395
57MINK10.57987346
58ADRBK20.55231196
59NTRK30.55125290
60MAPKAPK30.48129350
61ATM0.47886208
62BRAF0.47249514
63CSNK1A10.45021492
64STK110.44468012
65MKNK20.43610085
66NTRK20.43303645
67PRKCI0.40608800
68MYLK0.36729143
69MATK0.36669693
70YES10.36431488
71PRKACA0.36422158
72PRKCG0.36112802
73PRKACG0.35774873
74SGK4940.35551146
75SGK2230.35551146
76TIE10.35305160
77PRKAA20.34574777
78PIK3CA0.32075206
79BCKDK0.31698673
80RPS6KA20.31436730
81CASK0.30991535
82CAMK2D0.30733990
83MKNK10.29761796
84IKBKB0.29749530
85EIF2AK20.29649044
86PTK2B0.28349125
87DYRK30.25888688
88TESK20.25677625
89KSR10.24452891
90PRKCQ0.24437124
91BUB10.24297726
92PRKDC0.24160950
93PLK10.23828180
94CHUK0.22891640
95ATR0.22434614
96MAP3K120.21965684
97PRKCA0.21840354
98CSNK1D0.21563989
99PTK20.21533636
100CAMK2A0.21369038

Predicted pathways (KEGG)

RankGene SetZ-score
1Caffeine metabolism_Homo sapiens_hsa002323.76173175
2Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005633.30370049
3Maturity onset diabetes of the young_Homo sapiens_hsa049503.21854839
4Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.64944337
5Sulfur metabolism_Homo sapiens_hsa009202.61501047
6Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.53874285
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.44427689
8Protein export_Homo sapiens_hsa030602.38806807
9Steroid biosynthesis_Homo sapiens_hsa001002.30202582
10Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.29712847
11Propanoate metabolism_Homo sapiens_hsa006402.25686204
12Butanoate metabolism_Homo sapiens_hsa006502.07029552
13Vitamin digestion and absorption_Homo sapiens_hsa049772.02442245
14Fatty acid elongation_Homo sapiens_hsa000621.95717200
15Circadian rhythm_Homo sapiens_hsa047101.87257390
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.84812325
17Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.79479227
18Selenocompound metabolism_Homo sapiens_hsa004501.63625650
19ABC transporters_Homo sapiens_hsa020101.63375619
20Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.57390196
21Phototransduction_Homo sapiens_hsa047441.47988169
22Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.44413140
23Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.41213426
24Nicotine addiction_Homo sapiens_hsa050331.40800708
25Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.35814350
26SNARE interactions in vesicular transport_Homo sapiens_hsa041301.33335734
27Linoleic acid metabolism_Homo sapiens_hsa005911.32725038
28Regulation of autophagy_Homo sapiens_hsa041401.24511159
29Insulin secretion_Homo sapiens_hsa049111.21031532
30beta-Alanine metabolism_Homo sapiens_hsa004101.20955838
31Peroxisome_Homo sapiens_hsa041461.20461293
32Ether lipid metabolism_Homo sapiens_hsa005651.20369757
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.13151763
34Fatty acid metabolism_Homo sapiens_hsa012121.08978301
35Non-homologous end-joining_Homo sapiens_hsa034501.06250245
36Basal transcription factors_Homo sapiens_hsa030221.05927390
37Nitrogen metabolism_Homo sapiens_hsa009101.03246012
38Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.03121866
39Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.02242026
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.00920478
41Chemical carcinogenesis_Homo sapiens_hsa052041.00715175
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.99353156
43Retinol metabolism_Homo sapiens_hsa008300.98791552
44Collecting duct acid secretion_Homo sapiens_hsa049660.97952758
45Amphetamine addiction_Homo sapiens_hsa050310.97298781
46Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.97206139
47Steroid hormone biosynthesis_Homo sapiens_hsa001400.91477592
48Dopaminergic synapse_Homo sapiens_hsa047280.89947905
49Arginine and proline metabolism_Homo sapiens_hsa003300.89133013
50alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.88655353
51Vibrio cholerae infection_Homo sapiens_hsa051100.87172024
52Olfactory transduction_Homo sapiens_hsa047400.83005760
53GABAergic synapse_Homo sapiens_hsa047270.82629920
54Taste transduction_Homo sapiens_hsa047420.81241645
55Tryptophan metabolism_Homo sapiens_hsa003800.80470957
56Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.72509509
57RNA degradation_Homo sapiens_hsa030180.70246562
58Pancreatic secretion_Homo sapiens_hsa049720.70072287
59Bile secretion_Homo sapiens_hsa049760.70040207
60Drug metabolism - other enzymes_Homo sapiens_hsa009830.69917366
61Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.68804687
62Sphingolipid metabolism_Homo sapiens_hsa006000.68512461
63Fructose and mannose metabolism_Homo sapiens_hsa000510.66357923
64Type I diabetes mellitus_Homo sapiens_hsa049400.65727678
65Metabolic pathways_Homo sapiens_hsa011000.65235408
66Oocyte meiosis_Homo sapiens_hsa041140.65179424
67Glutathione metabolism_Homo sapiens_hsa004800.64855359
68Type II diabetes mellitus_Homo sapiens_hsa049300.64488570
69Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.63201373
70Circadian entrainment_Homo sapiens_hsa047130.61289199
71Long-term depression_Homo sapiens_hsa047300.60917225
72Serotonergic synapse_Homo sapiens_hsa047260.60849501
73Fanconi anemia pathway_Homo sapiens_hsa034600.59326226
74Gastric acid secretion_Homo sapiens_hsa049710.58867104
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.57560808
76TGF-beta signaling pathway_Homo sapiens_hsa043500.56857000
77Salivary secretion_Homo sapiens_hsa049700.55885911
78mRNA surveillance pathway_Homo sapiens_hsa030150.55270633
79RNA polymerase_Homo sapiens_hsa030200.54519557
80cAMP signaling pathway_Homo sapiens_hsa040240.53551620
81Ovarian steroidogenesis_Homo sapiens_hsa049130.52884844
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.51525989
83Morphine addiction_Homo sapiens_hsa050320.51176104
84Homologous recombination_Homo sapiens_hsa034400.50640411
85Oxidative phosphorylation_Homo sapiens_hsa001900.50446335
86N-Glycan biosynthesis_Homo sapiens_hsa005100.49337710
87Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.44948190
88Fatty acid degradation_Homo sapiens_hsa000710.44389757
89Vitamin B6 metabolism_Homo sapiens_hsa007500.42389211
90Complement and coagulation cascades_Homo sapiens_hsa046100.41643409
91Glutamatergic synapse_Homo sapiens_hsa047240.41481174
92mTOR signaling pathway_Homo sapiens_hsa041500.40288553
93Pyruvate metabolism_Homo sapiens_hsa006200.39487704
94Synaptic vesicle cycle_Homo sapiens_hsa047210.39257121
95Glycerolipid metabolism_Homo sapiens_hsa005610.36655111
96Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.36447821
97Vascular smooth muscle contraction_Homo sapiens_hsa042700.33982057
98Arachidonic acid metabolism_Homo sapiens_hsa005900.33884394
99AMPK signaling pathway_Homo sapiens_hsa041520.33770893
100Pyrimidine metabolism_Homo sapiens_hsa002400.32782546

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