

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | synaptic vesicle maturation (GO:0016188) | 5.62705536 |
| 2 | regulation of synaptic vesicle exocytosis (GO:2000300) | 4.70734920 |
| 3 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.66611907 |
| 4 | glutamate secretion (GO:0014047) | 4.63664442 |
| 5 | synaptic vesicle exocytosis (GO:0016079) | 4.62191813 |
| 6 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.60447863 |
| 7 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.53532200 |
| 8 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.47954418 |
| 9 | neuron cell-cell adhesion (GO:0007158) | 4.44984238 |
| 10 | postsynaptic membrane organization (GO:0001941) | 4.38337101 |
| 11 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.33621777 |
| 12 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.29645866 |
| 13 | neuronal action potential propagation (GO:0019227) | 4.24818448 |
| 14 | regulation of synaptic vesicle transport (GO:1902803) | 4.16081962 |
| 15 | presynaptic membrane assembly (GO:0097105) | 4.11779420 |
| 16 | gamma-aminobutyric acid transport (GO:0015812) | 4.05270265 |
| 17 | presynaptic membrane organization (GO:0097090) | 4.01792940 |
| 18 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 4.00722044 |
| 19 | neurotransmitter secretion (GO:0007269) | 3.97234669 |
| 20 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.96382188 |
| 21 | axonal fasciculation (GO:0007413) | 3.93320360 |
| 22 | vocalization behavior (GO:0071625) | 3.93042776 |
| 23 | protein localization to synapse (GO:0035418) | 3.85566573 |
| 24 | nucleobase catabolic process (GO:0046113) | 3.78778573 |
| 25 | synaptic transmission, glutamatergic (GO:0035249) | 3.77278893 |
| 26 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.72422114 |
| 27 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.71892149 |
| 28 | regulation of synapse structural plasticity (GO:0051823) | 3.71227303 |
| 29 | establishment of mitochondrion localization (GO:0051654) | 3.70405094 |
| 30 | neuron recognition (GO:0008038) | 3.65921188 |
| 31 | locomotory exploration behavior (GO:0035641) | 3.60611713 |
| 32 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.59818846 |
| 33 | dendritic spine morphogenesis (GO:0060997) | 3.59122970 |
| 34 | auditory behavior (GO:0031223) | 3.52162308 |
| 35 | neuron-neuron synaptic transmission (GO:0007270) | 3.49238267 |
| 36 | cerebellar granule cell differentiation (GO:0021707) | 3.46773611 |
| 37 | glutamate receptor signaling pathway (GO:0007215) | 3.44408611 |
| 38 | cellular potassium ion homeostasis (GO:0030007) | 3.41171461 |
| 39 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.40064030 |
| 40 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.39567039 |
| 41 | detection of calcium ion (GO:0005513) | 3.39074782 |
| 42 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 3.38696427 |
| 43 | exploration behavior (GO:0035640) | 3.37245603 |
| 44 | neuronal ion channel clustering (GO:0045161) | 3.34425891 |
| 45 | synapse assembly (GO:0007416) | 3.33284207 |
| 46 | membrane depolarization during action potential (GO:0086010) | 3.28558620 |
| 47 | positive regulation of synapse maturation (GO:0090129) | 3.27892535 |
| 48 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.23320011 |
| 49 | synaptic vesicle endocytosis (GO:0048488) | 3.19597375 |
| 50 | regulation of neurotransmitter secretion (GO:0046928) | 3.16759642 |
| 51 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.12850944 |
| 52 | cell migration in hindbrain (GO:0021535) | 3.12037446 |
| 53 | startle response (GO:0001964) | 3.11451125 |
| 54 | neurotransmitter transport (GO:0006836) | 3.11033186 |
| 55 | dendrite morphogenesis (GO:0048813) | 3.10265782 |
| 56 | proline transport (GO:0015824) | 3.09428689 |
| 57 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 3.09323801 |
| 58 | regulation of vesicle fusion (GO:0031338) | 3.08464538 |
| 59 | response to auditory stimulus (GO:0010996) | 3.07685087 |
| 60 | neuromuscular synaptic transmission (GO:0007274) | 3.04933810 |
| 61 | positive regulation of synapse assembly (GO:0051965) | 3.04276118 |
| 62 | regulation of cell communication by electrical coupling (GO:0010649) | 3.03979619 |
| 63 | regulation of neurotransmitter levels (GO:0001505) | 3.03261731 |
| 64 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.00635717 |
| 65 | transmission of nerve impulse (GO:0019226) | 2.98315968 |
| 66 | regulation of neuronal synaptic plasticity (GO:0048168) | 2.98202567 |
| 67 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.95130392 |
| 68 | positive regulation of dendritic spine development (GO:0060999) | 2.93519836 |
| 69 | regulation of neurotransmitter transport (GO:0051588) | 2.93384122 |
| 70 | regulation of dendritic spine morphogenesis (GO:0061001) | 2.93286225 |
| 71 | regulation of dendritic spine development (GO:0060998) | 2.91815235 |
| 72 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.91279915 |
| 73 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.89389262 |
| 74 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.87895785 |
| 75 | regulation of postsynaptic membrane potential (GO:0060078) | 2.87768114 |
| 76 | regulation of synapse maturation (GO:0090128) | 2.87542453 |
| 77 | urinary tract smooth muscle contraction (GO:0014848) | 2.85178883 |
| 78 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.84907377 |
| 79 | organelle transport along microtubule (GO:0072384) | 2.84881013 |
| 80 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.82462809 |
| 81 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.82090075 |
| 82 | central nervous system projection neuron axonogenesis (GO:0021952) | 2.79038044 |
| 83 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.78677299 |
| 84 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.78221434 |
| 85 | membrane depolarization (GO:0051899) | 2.77682978 |
| 86 | glycosphingolipid biosynthetic process (GO:0006688) | 2.77054884 |
| 87 | positive regulation of membrane potential (GO:0045838) | 2.75966153 |
| 88 | synapse organization (GO:0050808) | 2.75533849 |
| 89 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.74792705 |
| 90 | adult walking behavior (GO:0007628) | 2.74731018 |
| 91 | regulation of synapse assembly (GO:0051963) | 2.73909641 |
| 92 | positive regulation of mitochondrial fission (GO:0090141) | 2.70825824 |
| 93 | regulation of respiratory system process (GO:0044065) | 2.69057994 |
| 94 | mitochondrion transport along microtubule (GO:0047497) | 2.68917874 |
| 95 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.68917874 |
| 96 | sodium ion export (GO:0071436) | 2.68781218 |
| 97 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.68493384 |
| 98 | long-term memory (GO:0007616) | 2.67738896 |
| 99 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.67355112 |
| 100 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 2.67309080 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.27170267 |
| 2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.54445783 |
| 3 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.87794371 |
| 4 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.54098105 |
| 5 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.45227390 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.34852779 |
| 7 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.32984457 |
| 8 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.32553741 |
| 9 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.23558969 |
| 10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.16697292 |
| 11 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.09267973 |
| 12 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.03336967 |
| 13 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.02917250 |
| 14 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.98245657 |
| 15 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.97686765 |
| 16 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.96858938 |
| 17 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.94969628 |
| 18 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.92794344 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.92061798 |
| 20 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.90602280 |
| 21 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.89076054 |
| 22 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.87274596 |
| 23 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.84548043 |
| 24 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.83885885 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.82686719 |
| 26 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.79017726 |
| 27 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.78581235 |
| 28 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.78111395 |
| 29 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.77657397 |
| 30 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.77657397 |
| 31 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.76776453 |
| 32 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.76398185 |
| 33 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.76312458 |
| 34 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.76007547 |
| 35 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.67758596 |
| 36 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.65946314 |
| 37 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.64649036 |
| 38 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.62485880 |
| 39 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.62118831 |
| 40 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.61083706 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.58006008 |
| 42 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.57768124 |
| 43 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.57585747 |
| 44 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.55358549 |
| 45 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.53857920 |
| 46 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.48487442 |
| 47 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.44003269 |
| 48 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.43894843 |
| 49 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.43515658 |
| 50 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.42802641 |
| 51 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.42608443 |
| 52 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.42462645 |
| 53 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.41707517 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.37897475 |
| 55 | STAT3_23295773_ChIP-Seq_U87_Human | 1.36003587 |
| 56 | AR_25329375_ChIP-Seq_VCAP_Human | 1.35587571 |
| 57 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.34201745 |
| 58 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.33173839 |
| 59 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.32755507 |
| 60 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.27750611 |
| 61 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.26712111 |
| 62 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.25796027 |
| 63 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.25210385 |
| 64 | TCF4_23295773_ChIP-Seq_U87_Human | 1.24332329 |
| 65 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.24041772 |
| 66 | VDR_22108803_ChIP-Seq_LS180_Human | 1.23689432 |
| 67 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.22681250 |
| 68 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.22681250 |
| 69 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20240263 |
| 70 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.20238309 |
| 71 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.14914642 |
| 72 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.13478251 |
| 73 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.12463152 |
| 74 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.12290932 |
| 75 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.12290932 |
| 76 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.11670421 |
| 77 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.10583468 |
| 78 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10583468 |
| 79 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.09674770 |
| 80 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.08608917 |
| 81 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.08291917 |
| 82 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.06741765 |
| 83 | AR_19668381_ChIP-Seq_PC3_Human | 1.06682175 |
| 84 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.05801053 |
| 85 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05661514 |
| 86 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.04574448 |
| 87 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.04243198 |
| 88 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04220325 |
| 89 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.03560511 |
| 90 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.02753261 |
| 91 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02352969 |
| 92 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.01991134 |
| 93 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.01324244 |
| 94 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.00675275 |
| 95 | KDM2B_26808549_Chip-Seq_REH_Human | 1.00239888 |
| 96 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.99733158 |
| 97 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.98581926 |
| 98 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.98578840 |
| 99 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.97244970 |
| 100 | JUN_21703547_ChIP-Seq_K562_Human | 0.95743308 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004859_abnormal_synaptic_plasticity | 4.89723589 |
| 2 | MP0003880_abnormal_central_pattern | 4.24361701 |
| 3 | MP0004270_analgesia | 4.04827977 |
| 4 | MP0005423_abnormal_somatic_nervous | 3.38496136 |
| 5 | MP0003635_abnormal_synaptic_transmissio | 3.32451303 |
| 6 | MP0002063_abnormal_learning/memory/cond | 2.81838392 |
| 7 | MP0009046_muscle_twitch | 2.74135867 |
| 8 | MP0009745_abnormal_behavioral_response | 2.73126263 |
| 9 | MP0002064_seizures | 2.71434891 |
| 10 | MP0002822_catalepsy | 2.68976034 |
| 11 | MP0002272_abnormal_nervous_system | 2.67373389 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.39029971 |
| 13 | MP0002734_abnormal_mechanical_nocicepti | 2.37123118 |
| 14 | MP0001486_abnormal_startle_reflex | 2.35858404 |
| 15 | MP0002572_abnormal_emotion/affect_behav | 2.34471948 |
| 16 | MP0002735_abnormal_chemical_nociception | 2.20348776 |
| 17 | MP0006276_abnormal_autonomic_nervous | 2.15849270 |
| 18 | MP0000569_abnormal_digit_pigmentation | 2.14811782 |
| 19 | MP0000778_abnormal_nervous_system | 2.13092979 |
| 20 | MP0001501_abnormal_sleep_pattern | 2.05504208 |
| 21 | MP0001984_abnormal_olfaction | 2.05398683 |
| 22 | MP0003122_maternal_imprinting | 1.99104830 |
| 23 | MP0004145_abnormal_muscle_electrophysio | 1.92523887 |
| 24 | MP0002736_abnormal_nociception_after | 1.82790411 |
| 25 | MP0002067_abnormal_sensory_capabilities | 1.81365749 |
| 26 | MP0001970_abnormal_pain_threshold | 1.77516938 |
| 27 | MP0003787_abnormal_imprinting | 1.75343015 |
| 28 | MP0002733_abnormal_thermal_nociception | 1.70199238 |
| 29 | MP0008569_lethality_at_weaning | 1.70121282 |
| 30 | MP0001529_abnormal_vocalization | 1.69586835 |
| 31 | MP0002638_abnormal_pupillary_reflex | 1.68425802 |
| 32 | MP0004811_abnormal_neuron_physiology | 1.68219160 |
| 33 | MP0004924_abnormal_behavior | 1.67049248 |
| 34 | MP0005386_behavior/neurological_phenoty | 1.67049248 |
| 35 | MP0000751_myopathy | 1.62871252 |
| 36 | MP0004885_abnormal_endolymph | 1.58893661 |
| 37 | MP0001440_abnormal_grooming_behavior | 1.57391323 |
| 38 | MP0003879_abnormal_hair_cell | 1.54701262 |
| 39 | MP0002557_abnormal_social/conspecific_i | 1.53227153 |
| 40 | MP0004142_abnormal_muscle_tone | 1.52365017 |
| 41 | MP0002184_abnormal_innervation | 1.48654581 |
| 42 | MP0002882_abnormal_neuron_morphology | 1.45021274 |
| 43 | MP0010386_abnormal_urinary_bladder | 1.44089220 |
| 44 | MP0000955_abnormal_spinal_cord | 1.43633629 |
| 45 | MP0003633_abnormal_nervous_system | 1.43532883 |
| 46 | MP0001502_abnormal_circadian_rhythm | 1.42519303 |
| 47 | MP0005645_abnormal_hypothalamus_physiol | 1.39107222 |
| 48 | MP0002066_abnormal_motor_capabilities/c | 1.34007080 |
| 49 | MP0001905_abnormal_dopamine_level | 1.26641905 |
| 50 | MP0002909_abnormal_adrenal_gland | 1.26532559 |
| 51 | MP0004130_abnormal_muscle_cell | 1.23750952 |
| 52 | MP0004484_altered_response_of | 1.22517239 |
| 53 | MP0005187_abnormal_penis_morphology | 1.18394123 |
| 54 | MP0003631_nervous_system_phenotype | 1.17396963 |
| 55 | MP0004215_abnormal_myocardial_fiber | 1.16647983 |
| 56 | MP0003690_abnormal_glial_cell | 1.15231667 |
| 57 | MP0003329_amyloid_beta_deposits | 1.15015258 |
| 58 | MP0001986_abnormal_taste_sensitivity | 1.14655355 |
| 59 | MP0009780_abnormal_chondrocyte_physiolo | 1.13323812 |
| 60 | MP0000013_abnormal_adipose_tissue | 1.11747028 |
| 61 | MP0003121_genomic_imprinting | 1.10202883 |
| 62 | MP0005646_abnormal_pituitary_gland | 1.09996277 |
| 63 | MP0000749_muscle_degeneration | 1.08990531 |
| 64 | MP0002229_neurodegeneration | 1.05550847 |
| 65 | MP0005551_abnormal_eye_electrophysiolog | 1.04117132 |
| 66 | MP0003137_abnormal_impulse_conducting | 1.01746078 |
| 67 | MP0005620_abnormal_muscle_contractility | 1.01068072 |
| 68 | MP0002837_dystrophic_cardiac_calcinosis | 1.00980482 |
| 69 | MP0004036_abnormal_muscle_relaxation | 1.00135790 |
| 70 | MP0002152_abnormal_brain_morphology | 0.97692317 |
| 71 | MP0000920_abnormal_myelination | 0.97574441 |
| 72 | MP0002332_abnormal_exercise_endurance | 0.97248898 |
| 73 | MP0001177_atelectasis | 0.94084897 |
| 74 | MP0004742_abnormal_vestibular_system | 0.92346140 |
| 75 | MP0005535_abnormal_body_temperature | 0.89949683 |
| 76 | MP0004085_abnormal_heartbeat | 0.89648848 |
| 77 | MP0002106_abnormal_muscle_physiology | 0.86030482 |
| 78 | MP0004043_abnormal_pH_regulation | 0.85745974 |
| 79 | MP0003646_muscle_fatigue | 0.84465992 |
| 80 | MP0003634_abnormal_glial_cell | 0.83028801 |
| 81 | MP0002752_abnormal_somatic_nervous | 0.82629011 |
| 82 | MP0003632_abnormal_nervous_system | 0.78795335 |
| 83 | MP0001963_abnormal_hearing_physiology | 0.76992543 |
| 84 | MP0008874_decreased_physiological_sensi | 0.76531062 |
| 85 | MP0002069_abnormal_eating/drinking_beha | 0.76373915 |
| 86 | MP0000747_muscle_weakness | 0.76126173 |
| 87 | MP0004084_abnormal_cardiac_muscle | 0.76004194 |
| 88 | MP0001188_hyperpigmentation | 0.74416066 |
| 89 | MP0005253_abnormal_eye_physiology | 0.74384643 |
| 90 | MP0002102_abnormal_ear_morphology | 0.72126349 |
| 91 | MP0004510_myositis | 0.70944596 |
| 92 | MP0005369_muscle_phenotype | 0.70663352 |
| 93 | MP0002972_abnormal_cardiac_muscle | 0.69579998 |
| 94 | MP0001299_abnormal_eye_distance/ | 0.69562592 |
| 95 | MP0000759_abnormal_skeletal_muscle | 0.65925452 |
| 96 | MP0001943_abnormal_respiration | 0.65603424 |
| 97 | MP0001485_abnormal_pinna_reflex | 0.65174545 |
| 98 | MP0005499_abnormal_olfactory_system | 0.63491126 |
| 99 | MP0005394_taste/olfaction_phenotype | 0.63491126 |
| 100 | MP0003221_abnormal_cardiomyocyte_apopto | 0.63254129 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Focal motor seizures (HP:0011153) | 5.48422198 |
| 2 | Myokymia (HP:0002411) | 4.79232450 |
| 3 | Febrile seizures (HP:0002373) | 4.71357834 |
| 4 | Focal seizures (HP:0007359) | 4.65404303 |
| 5 | Atonic seizures (HP:0010819) | 4.38207707 |
| 6 | Epileptic encephalopathy (HP:0200134) | 4.07475656 |
| 7 | Hyperventilation (HP:0002883) | 4.04180846 |
| 8 | Abnormality of the corticospinal tract (HP:0002492) | 3.61780835 |
| 9 | Ankle clonus (HP:0011448) | 3.50174455 |
| 10 | Action tremor (HP:0002345) | 3.45996543 |
| 11 | Drooling (HP:0002307) | 3.43131468 |
| 12 | Urinary urgency (HP:0000012) | 3.36968484 |
| 13 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 3.36644165 |
| 14 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 3.36644165 |
| 15 | Spastic gait (HP:0002064) | 3.34653518 |
| 16 | Generalized tonic-clonic seizures (HP:0002069) | 3.33899654 |
| 17 | Dialeptic seizures (HP:0011146) | 3.33359374 |
| 18 | Absence seizures (HP:0002121) | 3.25844484 |
| 19 | Progressive cerebellar ataxia (HP:0002073) | 3.24104537 |
| 20 | Polyphagia (HP:0002591) | 3.22382443 |
| 21 | Limb dystonia (HP:0002451) | 3.21782622 |
| 22 | Muscle fiber inclusion bodies (HP:0100299) | 3.21525027 |
| 23 | Excessive salivation (HP:0003781) | 3.20751944 |
| 24 | Nemaline bodies (HP:0003798) | 3.15286419 |
| 25 | Amyotrophic lateral sclerosis (HP:0007354) | 3.14899127 |
| 26 | Exercise-induced muscle cramps (HP:0003710) | 3.11325395 |
| 27 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 3.05928115 |
| 28 | Urinary bladder sphincter dysfunction (HP:0002839) | 3.03491323 |
| 29 | Abnormal eating behavior (HP:0100738) | 3.03013111 |
| 30 | Impaired vibration sensation in the lower limbs (HP:0002166) | 3.02487620 |
| 31 | Gait imbalance (HP:0002141) | 3.02044467 |
| 32 | Broad-based gait (HP:0002136) | 2.99499117 |
| 33 | Epileptiform EEG discharges (HP:0011182) | 2.95878407 |
| 34 | Lower limb muscle weakness (HP:0007340) | 2.94583602 |
| 35 | Supranuclear gaze palsy (HP:0000605) | 2.93432705 |
| 36 | Absent speech (HP:0001344) | 2.88434470 |
| 37 | EEG with generalized epileptiform discharges (HP:0011198) | 2.82754583 |
| 38 | Hemiparesis (HP:0001269) | 2.82085016 |
| 39 | Diplopia (HP:0000651) | 2.80057841 |
| 40 | Abnormality of binocular vision (HP:0011514) | 2.80057841 |
| 41 | Mutism (HP:0002300) | 2.71712165 |
| 42 | Hypsarrhythmia (HP:0002521) | 2.63311435 |
| 43 | Postural instability (HP:0002172) | 2.55893623 |
| 44 | Frequent falls (HP:0002359) | 2.54201192 |
| 45 | Papilledema (HP:0001085) | 2.51091704 |
| 46 | Fetal akinesia sequence (HP:0001989) | 2.50804900 |
| 47 | Truncal ataxia (HP:0002078) | 2.45184143 |
| 48 | Medial flaring of the eyebrow (HP:0010747) | 2.44492791 |
| 49 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.43260680 |
| 50 | Failure to thrive in infancy (HP:0001531) | 2.40613321 |
| 51 | Congenital primary aphakia (HP:0007707) | 2.40246341 |
| 52 | Genetic anticipation (HP:0003743) | 2.37758245 |
| 53 | Agitation (HP:0000713) | 2.35185158 |
| 54 | Specific learning disability (HP:0001328) | 2.35172017 |
| 55 | Rimmed vacuoles (HP:0003805) | 2.32791482 |
| 56 | Abnormality of the lower motor neuron (HP:0002366) | 2.30784963 |
| 57 | Type 1 muscle fiber predominance (HP:0003803) | 2.25733180 |
| 58 | Pheochromocytoma (HP:0002666) | 2.25347514 |
| 59 | Bundle branch block (HP:0011710) | 2.24773075 |
| 60 | Nephrogenic diabetes insipidus (HP:0009806) | 2.23804440 |
| 61 | Amblyopia (HP:0000646) | 2.23063367 |
| 62 | Impaired vibratory sensation (HP:0002495) | 2.22164303 |
| 63 | Scanning speech (HP:0002168) | 2.22137141 |
| 64 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.19821450 |
| 65 | Myotonia (HP:0002486) | 2.19741323 |
| 66 | Status epilepticus (HP:0002133) | 2.18881181 |
| 67 | Poor eye contact (HP:0000817) | 2.18508694 |
| 68 | Prolonged QT interval (HP:0001657) | 2.16332506 |
| 69 | Neurofibrillary tangles (HP:0002185) | 2.13763756 |
| 70 | Abnormal EKG (HP:0003115) | 2.12145792 |
| 71 | Spastic tetraplegia (HP:0002510) | 2.11834128 |
| 72 | Clonus (HP:0002169) | 2.10781013 |
| 73 | Akinesia (HP:0002304) | 2.10425178 |
| 74 | Intention tremor (HP:0002080) | 2.09332268 |
| 75 | Hemiplegia (HP:0002301) | 2.09033227 |
| 76 | Calf muscle hypertrophy (HP:0008981) | 2.08840076 |
| 77 | Dysdiadochokinesis (HP:0002075) | 2.02918794 |
| 78 | Inappropriate behavior (HP:0000719) | 2.01443937 |
| 79 | Muscle fiber splitting (HP:0003555) | 2.00571863 |
| 80 | Inability to walk (HP:0002540) | 1.99751388 |
| 81 | Exercise-induced myalgia (HP:0003738) | 1.99253316 |
| 82 | Rapidly progressive (HP:0003678) | 1.99010885 |
| 83 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.98800230 |
| 84 | Depression (HP:0000716) | 1.96148669 |
| 85 | Termporal pattern (HP:0011008) | 1.95961789 |
| 86 | Insidious onset (HP:0003587) | 1.95961789 |
| 87 | Gaze-evoked nystagmus (HP:0000640) | 1.94279491 |
| 88 | EMG: myopathic abnormalities (HP:0003458) | 1.92801225 |
| 89 | Abnormality of salivation (HP:0100755) | 1.92694648 |
| 90 | Peripheral hypomyelination (HP:0007182) | 1.92539459 |
| 91 | Hypoplasia of the corpus callosum (HP:0002079) | 1.92525540 |
| 92 | Abnormality of the calf musculature (HP:0001430) | 1.91830610 |
| 93 | Paraplegia (HP:0010550) | 1.91458017 |
| 94 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.91254891 |
| 95 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.91254891 |
| 96 | Torticollis (HP:0000473) | 1.91089763 |
| 97 | Dysmetria (HP:0001310) | 1.90474266 |
| 98 | Exotropia (HP:0000577) | 1.89371414 |
| 99 | Sudden death (HP:0001699) | 1.88055489 |
| 100 | Syncope (HP:0001279) | 1.85679281 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MARK1 | 5.14224246 |
| 2 | CASK | 4.02522631 |
| 3 | NTRK3 | 2.90640194 |
| 4 | MAP3K4 | 2.71497768 |
| 5 | EPHA4 | 2.64942118 |
| 6 | MAPK13 | 2.40358867 |
| 7 | DAPK2 | 2.40016202 |
| 8 | NTRK2 | 2.29861609 |
| 9 | PHKG2 | 2.24661508 |
| 10 | PHKG1 | 2.24661508 |
| 11 | PINK1 | 2.19495988 |
| 12 | OBSCN | 2.19174205 |
| 13 | PAK6 | 2.05723011 |
| 14 | UHMK1 | 1.95916624 |
| 15 | CAMKK2 | 1.94882390 |
| 16 | MAP2K7 | 1.93080138 |
| 17 | MAP4K2 | 1.88025153 |
| 18 | ERBB3 | 1.83754877 |
| 19 | BCR | 1.80189080 |
| 20 | PAK3 | 1.65198011 |
| 21 | PRKD3 | 1.54074494 |
| 22 | EPHA3 | 1.52112795 |
| 23 | MINK1 | 1.50965522 |
| 24 | WNK3 | 1.47002791 |
| 25 | MAP2K4 | 1.45627818 |
| 26 | CSNK1G2 | 1.36692130 |
| 27 | CAMKK1 | 1.36109865 |
| 28 | CDK5 | 1.26786249 |
| 29 | SIK2 | 1.20928641 |
| 30 | PLK2 | 1.20353966 |
| 31 | SGK223 | 1.18779880 |
| 32 | SGK494 | 1.18779880 |
| 33 | PRKCG | 1.15846837 |
| 34 | CAMK2B | 1.11169235 |
| 35 | SGK2 | 1.10230743 |
| 36 | CAMK2A | 1.07040911 |
| 37 | CSNK1G3 | 1.03170515 |
| 38 | DYRK1A | 1.00309759 |
| 39 | LIMK1 | 0.98456233 |
| 40 | KSR1 | 0.96171435 |
| 41 | CAMK1 | 0.95123083 |
| 42 | TNIK | 0.94652929 |
| 43 | PNCK | 0.94371227 |
| 44 | DYRK2 | 0.94358041 |
| 45 | FRK | 0.92756341 |
| 46 | CSNK1A1L | 0.90121171 |
| 47 | NTRK1 | 0.88977174 |
| 48 | PKN1 | 0.87159308 |
| 49 | MAPK12 | 0.86731656 |
| 50 | CDK19 | 0.85825775 |
| 51 | PRKCE | 0.83192457 |
| 52 | CAMK4 | 0.80025903 |
| 53 | CSNK1G1 | 0.79094922 |
| 54 | CAMK2G | 0.78517948 |
| 55 | GRK5 | 0.76575778 |
| 56 | MAP3K6 | 0.69589158 |
| 57 | MARK2 | 0.68909643 |
| 58 | MAP3K9 | 0.66608546 |
| 59 | CDK14 | 0.66333352 |
| 60 | CAMK2D | 0.64837062 |
| 61 | DYRK1B | 0.64036549 |
| 62 | SGK3 | 0.61188159 |
| 63 | CDK18 | 0.60273551 |
| 64 | DYRK3 | 0.60070047 |
| 65 | KSR2 | 0.59410134 |
| 66 | STK38 | 0.58762256 |
| 67 | CDK15 | 0.57153654 |
| 68 | BRD4 | 0.57041049 |
| 69 | TRIM28 | 0.56847901 |
| 70 | SGK1 | 0.56758103 |
| 71 | PRKG1 | 0.56692567 |
| 72 | STK11 | 0.53023863 |
| 73 | EPHB2 | 0.51349392 |
| 74 | CDK11A | 0.50433957 |
| 75 | ADRBK2 | 0.48852033 |
| 76 | PRKCZ | 0.47914183 |
| 77 | PRKACA | 0.44261990 |
| 78 | TAOK3 | 0.43555807 |
| 79 | RPS6KA3 | 0.43055001 |
| 80 | RET | 0.41723785 |
| 81 | PRKCH | 0.41592814 |
| 82 | PRKAA1 | 0.41249865 |
| 83 | CCNB1 | 0.40809160 |
| 84 | MAPK10 | 0.40053148 |
| 85 | OXSR1 | 0.38528658 |
| 86 | MAP3K12 | 0.36398516 |
| 87 | INSRR | 0.35989582 |
| 88 | MAPK7 | 0.35734965 |
| 89 | FYN | 0.35683555 |
| 90 | CSNK1D | 0.35586054 |
| 91 | ROCK2 | 0.35258139 |
| 92 | PRKACB | 0.33618052 |
| 93 | MAPK4 | 0.31981902 |
| 94 | TYRO3 | 0.31538125 |
| 95 | MAP3K5 | 0.29985883 |
| 96 | DAPK1 | 0.29964479 |
| 97 | FER | 0.26112275 |
| 98 | PTK2B | 0.25988727 |
| 99 | LATS2 | 0.25758979 |
| 100 | ROCK1 | 0.25675012 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Nicotine addiction_Homo sapiens_hsa05033 | 4.17578164 |
| 2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.09791369 |
| 3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.96091768 |
| 4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.69497759 |
| 5 | Circadian entrainment_Homo sapiens_hsa04713 | 2.67639607 |
| 6 | Morphine addiction_Homo sapiens_hsa05032 | 2.53743026 |
| 7 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.45789049 |
| 8 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.40454307 |
| 9 | Insulin secretion_Homo sapiens_hsa04911 | 2.19815356 |
| 10 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.17589638 |
| 11 | Cocaine addiction_Homo sapiens_hsa05030 | 2.04740187 |
| 12 | Long-term potentiation_Homo sapiens_hsa04720 | 2.00574246 |
| 13 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.86671822 |
| 14 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.75924295 |
| 15 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.71708576 |
| 16 | Circadian rhythm_Homo sapiens_hsa04710 | 1.70195269 |
| 17 | Renin secretion_Homo sapiens_hsa04924 | 1.61913218 |
| 18 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.59362495 |
| 19 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.56610760 |
| 20 | Taste transduction_Homo sapiens_hsa04742 | 1.51884857 |
| 21 | Salivary secretion_Homo sapiens_hsa04970 | 1.49882734 |
| 22 | Long-term depression_Homo sapiens_hsa04730 | 1.45517111 |
| 23 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.44935640 |
| 24 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.44089175 |
| 25 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.43368830 |
| 26 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.42916968 |
| 27 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.42476274 |
| 28 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.36225260 |
| 29 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.30461936 |
| 30 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.25730868 |
| 31 | Axon guidance_Homo sapiens_hsa04360 | 1.25459881 |
| 32 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.23552745 |
| 33 | Gap junction_Homo sapiens_hsa04540 | 1.18140731 |
| 34 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.13828583 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.12066740 |
| 36 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.11670514 |
| 37 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.11515355 |
| 38 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.10459143 |
| 39 | Olfactory transduction_Homo sapiens_hsa04740 | 1.10088269 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.08564398 |
| 41 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.05827073 |
| 42 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.03977365 |
| 43 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.02729008 |
| 44 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.98611452 |
| 45 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.97792021 |
| 46 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.95102316 |
| 47 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.91738811 |
| 48 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.89465822 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.89173840 |
| 50 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.87949075 |
| 51 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.86130370 |
| 52 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.84943254 |
| 53 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.83365064 |
| 54 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.78831478 |
| 55 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.78016873 |
| 56 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.77243899 |
| 57 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.76311154 |
| 58 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.72214053 |
| 59 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.64807099 |
| 60 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.62743820 |
| 61 | Melanogenesis_Homo sapiens_hsa04916 | 0.60618216 |
| 62 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.60066557 |
| 63 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.59738669 |
| 64 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.57685313 |
| 65 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.55948387 |
| 66 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.55198842 |
| 67 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.54959276 |
| 68 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.54548581 |
| 69 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.53485203 |
| 70 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.53286787 |
| 71 | Alzheimers disease_Homo sapiens_hsa05010 | 0.52616160 |
| 72 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.50705823 |
| 73 | Glioma_Homo sapiens_hsa05214 | 0.48191504 |
| 74 | Phagosome_Homo sapiens_hsa04145 | 0.48144774 |
| 75 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.45023636 |
| 76 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.43374518 |
| 77 | Endocytosis_Homo sapiens_hsa04144 | 0.42219129 |
| 78 | Alcoholism_Homo sapiens_hsa05034 | 0.42009954 |
| 79 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.41580837 |
| 80 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40863683 |
| 81 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.40346663 |
| 82 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38646962 |
| 83 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.36573350 |
| 84 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.35749272 |
| 85 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.34501282 |
| 86 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.33871503 |
| 87 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.31226782 |
| 88 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.31046006 |
| 89 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.30962806 |
| 90 | ABC transporters_Homo sapiens_hsa02010 | 0.30644871 |
| 91 | Parkinsons disease_Homo sapiens_hsa05012 | 0.29876266 |
| 92 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.29807409 |
| 93 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.29340319 |
| 94 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.26381909 |
| 95 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.25566759 |
| 96 | Salmonella infection_Homo sapiens_hsa05132 | 0.25276325 |
| 97 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.23865845 |
| 98 | Bile secretion_Homo sapiens_hsa04976 | 0.23515455 |
| 99 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.23439865 |
| 100 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.22641142 |

