Rank | Gene Set | Z-score |
---|---|---|
1 | chromatin remodeling at centromere (GO:0031055) | 4.93567394 |
2 | CENP-A containing nucleosome assembly (GO:0034080) | 4.84938456 |
3 | mitotic sister chromatid cohesion (GO:0007064) | 4.62432264 |
4 | mitotic metaphase plate congression (GO:0007080) | 4.57131874 |
5 | nuclear pore complex assembly (GO:0051292) | 4.55350386 |
6 | protein localization to kinetochore (GO:0034501) | 4.50263221 |
7 | regulation of helicase activity (GO:0051095) | 4.36751615 |
8 | nuclear pore organization (GO:0006999) | 4.34242243 |
9 | establishment of integrated proviral latency (GO:0075713) | 4.31588798 |
10 | histone exchange (GO:0043486) | 4.28175255 |
11 | pre-miRNA processing (GO:0031054) | 4.15897734 |
12 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 4.14562174 |
13 | negative regulation of sister chromatid segregation (GO:0033046) | 4.14562174 |
14 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 4.14562174 |
15 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 4.14562174 |
16 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 4.14562174 |
17 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.12718139 |
18 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.12718139 |
19 | DNA replication-independent nucleosome organization (GO:0034724) | 4.10331967 |
20 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.10331967 |
21 | negative regulation of chromosome segregation (GO:0051985) | 4.05736844 |
22 | metaphase plate congression (GO:0051310) | 4.02759784 |
23 | protein localization to chromosome, centromeric region (GO:0071459) | 3.95369426 |
24 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.87952426 |
25 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.87952426 |
26 | spindle checkpoint (GO:0031577) | 3.87908659 |
27 | mitotic spindle checkpoint (GO:0071174) | 3.86883506 |
28 | DNA replication checkpoint (GO:0000076) | 3.85143881 |
29 | regulation of centriole replication (GO:0046599) | 3.79765345 |
30 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.76989389 |
31 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.76989389 |
32 | regulation of sister chromatid segregation (GO:0033045) | 3.76989389 |
33 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.70185057 |
34 | regulation of histone H3-K9 methylation (GO:0051570) | 3.69895795 |
35 | regulation of gene silencing by RNA (GO:0060966) | 3.68598444 |
36 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.68598444 |
37 | regulation of gene silencing by miRNA (GO:0060964) | 3.68598444 |
38 | mitotic spindle assembly checkpoint (GO:0007094) | 3.66832592 |
39 | synapsis (GO:0007129) | 3.59688321 |
40 | spindle assembly checkpoint (GO:0071173) | 3.59506993 |
41 | regulation of chromosome segregation (GO:0051983) | 3.54969822 |
42 | regulation of meiosis I (GO:0060631) | 3.51429287 |
43 | kinetochore organization (GO:0051383) | 3.47324003 |
44 | mitotic G2/M transition checkpoint (GO:0044818) | 3.45704266 |
45 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.45509426 |
46 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.45509426 |
47 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.45509426 |
48 | establishment of chromosome localization (GO:0051303) | 3.40689824 |
49 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.38494997 |
50 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.38494997 |
51 | DNA double-strand break processing (GO:0000729) | 3.37235992 |
52 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.34811925 |
53 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.34493525 |
54 | regulation of DNA endoreduplication (GO:0032875) | 3.33885216 |
55 | negative regulation of DNA recombination (GO:0045910) | 3.31269736 |
56 | negative regulation of mitosis (GO:0045839) | 3.30325689 |
57 | ATP-dependent chromatin remodeling (GO:0043044) | 3.28518934 |
58 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.26684210 |
59 | ribosome assembly (GO:0042255) | 3.25061153 |
60 | DNA strand elongation (GO:0022616) | 3.24411089 |
61 | pore complex assembly (GO:0046931) | 3.23636075 |
62 | paraxial mesoderm development (GO:0048339) | 3.22192660 |
63 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.21270120 |
64 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.21270120 |
65 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.19379716 |
66 | sister chromatid segregation (GO:0000819) | 3.18265509 |
67 | regulation of DNA methylation (GO:0044030) | 3.16303118 |
68 | mitotic sister chromatid segregation (GO:0000070) | 3.16164663 |
69 | IMP biosynthetic process (GO:0006188) | 3.14270892 |
70 | histone mRNA metabolic process (GO:0008334) | 3.11132187 |
71 | establishment of viral latency (GO:0019043) | 3.11007397 |
72 | protein localization to chromosome (GO:0034502) | 3.10031998 |
73 | DNA synthesis involved in DNA repair (GO:0000731) | 3.08133309 |
74 | DNA damage response, detection of DNA damage (GO:0042769) | 3.07417383 |
75 | mitotic nuclear envelope disassembly (GO:0007077) | 3.06309827 |
76 | response to X-ray (GO:0010165) | 3.05751729 |
77 | sister chromatid cohesion (GO:0007062) | 3.05671893 |
78 | heterochromatin organization (GO:0070828) | 3.05244707 |
79 | kinetochore assembly (GO:0051382) | 3.03547181 |
80 | protein complex localization (GO:0031503) | 3.03332663 |
81 | telomere maintenance via telomerase (GO:0007004) | 3.03045367 |
82 | negative regulation of DNA repair (GO:0045738) | 3.02581201 |
83 | purine nucleobase biosynthetic process (GO:0009113) | 3.02105691 |
84 | negative regulation of nuclear division (GO:0051784) | 3.01442499 |
85 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.98289444 |
86 | non-recombinational repair (GO:0000726) | 2.98289444 |
87 | mitotic chromosome condensation (GO:0007076) | 2.97411092 |
88 | positive regulation of chromosome segregation (GO:0051984) | 2.96340104 |
89 | anterior/posterior axis specification, embryo (GO:0008595) | 2.95198248 |
90 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) | 2.94081337 |
91 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 2.93942037 |
92 | nuclear envelope disassembly (GO:0051081) | 2.91676162 |
93 | membrane disassembly (GO:0030397) | 2.91676162 |
94 | regulation of centrosome cycle (GO:0046605) | 2.90493782 |
95 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.90234693 |
96 | chromatin assembly or disassembly (GO:0006333) | 2.88811060 |
97 | female gonad development (GO:0008585) | 2.88754944 |
98 | cellular protein complex localization (GO:0034629) | 2.88549485 |
99 | DNA ligation (GO:0006266) | 2.87121059 |
100 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.85415808 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.78252082 |
2 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.06678524 |
3 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.89401598 |
4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.72836776 |
5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.46812750 |
6 | * FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.00953274 |
7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.96952084 |
8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.88922180 |
9 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.78457653 |
10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.74974450 |
11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.61643129 |
12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.57805613 |
13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.52326746 |
14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.47925208 |
15 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.46000356 |
16 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.30337963 |
17 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.30337963 |
18 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.30337963 |
19 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.19281452 |
20 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.15181883 |
21 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.08347152 |
22 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.06399539 |
23 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.04761292 |
24 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.98097649 |
25 | EWS_26573619_Chip-Seq_HEK293_Human | 1.96390071 |
26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.93926232 |
27 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.92311136 |
28 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.89570889 |
29 | FUS_26573619_Chip-Seq_HEK293_Human | 1.86847121 |
30 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.83161928 |
31 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.83043195 |
32 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.77607812 |
33 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.76681636 |
34 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.74320345 |
35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.74318274 |
36 | * NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.72160851 |
37 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.69581478 |
38 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.66856367 |
39 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.66133750 |
40 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.61783087 |
41 | * SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.60455983 |
42 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.56204382 |
43 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.55489202 |
44 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.51436351 |
45 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.51302617 |
46 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.49479148 |
47 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.48301791 |
48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.48192279 |
49 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.47257018 |
50 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.45503399 |
51 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.44805597 |
52 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.41608673 |
53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.38937041 |
54 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.37787187 |
55 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.37531495 |
56 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.35852682 |
57 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.32572455 |
58 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.32564580 |
59 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.25998347 |
60 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.25285066 |
61 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.25215401 |
62 | P300_19829295_ChIP-Seq_ESCs_Human | 1.23749758 |
63 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.22966275 |
64 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.20082974 |
65 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.18864562 |
66 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14955350 |
67 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.13240713 |
68 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.13125623 |
69 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.12531556 |
70 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.11609820 |
71 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.09247760 |
72 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.08958045 |
73 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08602655 |
74 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.06301928 |
75 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.06238543 |
76 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.05596399 |
77 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.02192294 |
78 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.00616620 |
79 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.99556910 |
80 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.99367117 |
81 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.99065374 |
82 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.94668372 |
83 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.94004203 |
84 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.93982513 |
85 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.92860894 |
86 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.91227766 |
87 | VDR_22108803_ChIP-Seq_LS180_Human | 0.87791200 |
88 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 0.86518604 |
89 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.82730108 |
90 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.81886984 |
91 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.80202400 |
92 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.79196286 |
93 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.78069107 |
94 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.76584411 |
95 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.76488043 |
96 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.76232784 |
97 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.75963782 |
98 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.75915773 |
99 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.75179155 |
100 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.73437942 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008057_abnormal_DNA_replication | 4.31153482 |
2 | MP0008877_abnormal_DNA_methylation | 4.09817122 |
3 | MP0003941_abnormal_skin_development | 3.74951041 |
4 | MP0003693_abnormal_embryo_hatching | 3.71785192 |
5 | MP0003890_abnormal_embryonic-extraembry | 3.56870902 |
6 | MP0008058_abnormal_DNA_repair | 3.48741376 |
7 | MP0010094_abnormal_chromosome_stability | 3.43985828 |
8 | MP0004957_abnormal_blastocyst_morpholog | 3.43621777 |
9 | MP0006292_abnormal_olfactory_placode | 3.30699368 |
10 | MP0003111_abnormal_nucleus_morphology | 3.03081721 |
11 | MP0003077_abnormal_cell_cycle | 2.87971101 |
12 | MP0003718_maternal_effect | 2.59826701 |
13 | MP0008932_abnormal_embryonic_tissue | 2.43307877 |
14 | MP0008007_abnormal_cellular_replicative | 2.43274550 |
15 | MP0001293_anophthalmia | 2.35730439 |
16 | MP0002254_reproductive_system_inflammat | 1.97779639 |
17 | MP0010352_gastrointestinal_tract_polyps | 1.97426120 |
18 | MP0003937_abnormal_limbs/digits/tail_de | 1.95295035 |
19 | MP0003567_abnormal_fetal_cardiomyocyte | 1.95183766 |
20 | MP0001730_embryonic_growth_arrest | 1.76960702 |
21 | MP0000350_abnormal_cell_proliferation | 1.72868052 |
22 | MP0009672_abnormal_birth_weight | 1.72847257 |
23 | MP0003119_abnormal_digestive_system | 1.70166675 |
24 | MP0001188_hyperpigmentation | 1.70151455 |
25 | MP0002084_abnormal_developmental_patter | 1.63826112 |
26 | MP0003121_genomic_imprinting | 1.63068819 |
27 | MP0001286_abnormal_eye_development | 1.59285142 |
28 | MP0002697_abnormal_eye_size | 1.58800475 |
29 | MP0002085_abnormal_embryonic_tissue | 1.56698824 |
30 | MP0005380_embryogenesis_phenotype | 1.53354207 |
31 | MP0001672_abnormal_embryogenesis/_devel | 1.53354207 |
32 | MP0010030_abnormal_orbit_morphology | 1.48877852 |
33 | MP0009703_decreased_birth_body | 1.47545264 |
34 | MP0001697_abnormal_embryo_size | 1.46593492 |
35 | MP0008789_abnormal_olfactory_epithelium | 1.44483719 |
36 | MP0002233_abnormal_nose_morphology | 1.43842184 |
37 | MP0002210_abnormal_sex_determination | 1.36097217 |
38 | MP0009697_abnormal_copulation | 1.34005103 |
39 | MP0003984_embryonic_growth_retardation | 1.30783779 |
40 | MP0002088_abnormal_embryonic_growth/wei | 1.29458199 |
41 | MP0010307_abnormal_tumor_latency | 1.29136038 |
42 | MP0001529_abnormal_vocalization | 1.28178370 |
43 | MP0003786_premature_aging | 1.24997516 |
44 | MP0001929_abnormal_gametogenesis | 1.24804515 |
45 | MP0005499_abnormal_olfactory_system | 1.22680739 |
46 | MP0005394_taste/olfaction_phenotype | 1.22680739 |
47 | MP0004197_abnormal_fetal_growth/weight/ | 1.22263840 |
48 | MP0000537_abnormal_urethra_morphology | 1.21583214 |
49 | MP0003787_abnormal_imprinting | 1.20614837 |
50 | MP0001145_abnormal_male_reproductive | 1.19038885 |
51 | MP0000049_abnormal_middle_ear | 1.16544744 |
52 | MP0002080_prenatal_lethality | 1.15313050 |
53 | MP0003755_abnormal_palate_morphology | 1.14934425 |
54 | MP0004133_heterotaxia | 1.14127599 |
55 | MP0000653_abnormal_sex_gland | 1.13568586 |
56 | MP0001177_atelectasis | 1.13399089 |
57 | MP0002111_abnormal_tail_morphology | 1.10771821 |
58 | MP0002751_abnormal_autonomic_nervous | 1.10565448 |
59 | MP0002102_abnormal_ear_morphology | 1.09112211 |
60 | MP0003861_abnormal_nervous_system | 1.04927386 |
61 | MP0002086_abnormal_extraembryonic_tissu | 1.02522879 |
62 | MP0001299_abnormal_eye_distance/ | 1.02173221 |
63 | MP0006035_abnormal_mitochondrial_morpho | 1.01552979 |
64 | MP0003221_abnormal_cardiomyocyte_apopto | 0.99743292 |
65 | MP0008995_early_reproductive_senescence | 0.98497768 |
66 | MP0002938_white_spotting | 0.98228315 |
67 | MP0003935_abnormal_craniofacial_develop | 0.97453536 |
68 | MP0000428_abnormal_craniofacial_morphol | 0.96996480 |
69 | MP0000313_abnormal_cell_death | 0.96830163 |
70 | MP0003136_yellow_coat_color | 0.95220504 |
71 | MP0002092_abnormal_eye_morphology | 0.93967597 |
72 | MP0002160_abnormal_reproductive_system | 0.92190509 |
73 | MP0000432_abnormal_head_morphology | 0.91224175 |
74 | MP0003122_maternal_imprinting | 0.91182788 |
75 | MP0000647_abnormal_sebaceous_gland | 0.89307108 |
76 | MP0003315_abnormal_perineum_morphology | 0.88841838 |
77 | MP0001119_abnormal_female_reproductive | 0.87146584 |
78 | MP0002277_abnormal_respiratory_mucosa | 0.85704209 |
79 | MP0000631_abnormal_neuroendocrine_gland | 0.85631784 |
80 | MP0005395_other_phenotype | 0.85233479 |
81 | MP0000579_abnormal_nail_morphology | 0.84849089 |
82 | MP0009250_abnormal_appendicular_skeleto | 0.84449457 |
83 | MP0002396_abnormal_hematopoietic_system | 0.83085177 |
84 | MP0000762_abnormal_tongue_morphology | 0.82369073 |
85 | MP0006072_abnormal_retinal_apoptosis | 0.82074559 |
86 | MP0000778_abnormal_nervous_system | 0.80613201 |
87 | MP0003123_paternal_imprinting | 0.79122043 |
88 | MP0003698_abnormal_male_reproductive | 0.78573462 |
89 | MP0003699_abnormal_female_reproductive | 0.78142936 |
90 | MP0005084_abnormal_gallbladder_morpholo | 0.77531610 |
91 | MP0000516_abnormal_urinary_system | 0.74994309 |
92 | MP0005367_renal/urinary_system_phenotyp | 0.74994309 |
93 | MP0005187_abnormal_penis_morphology | 0.73984648 |
94 | MP0002081_perinatal_lethality | 0.71630728 |
95 | MP0005391_vision/eye_phenotype | 0.71479871 |
96 | MP0003385_abnormal_body_wall | 0.70065564 |
97 | MP0002161_abnormal_fertility/fecundity | 0.69360666 |
98 | MP0001340_abnormal_eyelid_morphology | 0.68317252 |
99 | MP0003115_abnormal_respiratory_system | 0.67480247 |
100 | MP0009053_abnormal_anal_canal | 0.64484383 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Colon cancer (HP:0003003) | 4.39379192 |
2 | Abnormality of the labia minora (HP:0012880) | 4.20651824 |
3 | Septo-optic dysplasia (HP:0100842) | 3.91381049 |
4 | Chromsome breakage (HP:0040012) | 3.84429499 |
5 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.75885488 |
6 | Volvulus (HP:0002580) | 3.72193612 |
7 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.36253224 |
8 | Abnormal lung lobation (HP:0002101) | 3.29858763 |
9 | Abnormality of chromosome stability (HP:0003220) | 3.26111481 |
10 | Embryonal renal neoplasm (HP:0011794) | 3.24255227 |
11 | Medulloblastoma (HP:0002885) | 3.05084838 |
12 | Meckel diverticulum (HP:0002245) | 2.97920621 |
13 | Birth length less than 3rd percentile (HP:0003561) | 2.95731316 |
14 | Abnormality of the septum pellucidum (HP:0007375) | 2.85175555 |
15 | Abnormality of the ileum (HP:0001549) | 2.79634238 |
16 | Rhabdomyosarcoma (HP:0002859) | 2.76746571 |
17 | Absent septum pellucidum (HP:0001331) | 2.67148781 |
18 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.64494986 |
19 | Cortical dysplasia (HP:0002539) | 2.54079636 |
20 | Ependymoma (HP:0002888) | 2.48627543 |
21 | Small intestinal stenosis (HP:0012848) | 2.41410304 |
22 | Duodenal stenosis (HP:0100867) | 2.41410304 |
23 | Supernumerary spleens (HP:0009799) | 2.37250688 |
24 | Abnormality of the duodenum (HP:0002246) | 2.35573230 |
25 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.35518560 |
26 | Shoulder girdle muscle weakness (HP:0003547) | 2.34523642 |
27 | Abnormality of the preputium (HP:0100587) | 2.34083067 |
28 | Abnormality of methionine metabolism (HP:0010901) | 2.31395366 |
29 | Stenosis of the external auditory canal (HP:0000402) | 2.30903949 |
30 | Hepatoblastoma (HP:0002884) | 2.28337060 |
31 | Increased nuchal translucency (HP:0010880) | 2.25935918 |
32 | Absent radius (HP:0003974) | 2.24804589 |
33 | Abnormal hair whorl (HP:0010721) | 2.22995237 |
34 | Ectopic kidney (HP:0000086) | 2.22546591 |
35 | Carpal bone hypoplasia (HP:0001498) | 2.21871870 |
36 | Multiple enchondromatosis (HP:0005701) | 2.21086042 |
37 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.20687520 |
38 | Papillary thyroid carcinoma (HP:0002895) | 2.14240875 |
39 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.11957741 |
40 | Neoplasm of the colon (HP:0100273) | 2.10444056 |
41 | Bilateral microphthalmos (HP:0007633) | 2.09704873 |
42 | Aplasia involving forearm bones (HP:0009822) | 2.08003830 |
43 | Absent forearm bone (HP:0003953) | 2.08003830 |
44 | Oligodactyly (hands) (HP:0001180) | 2.04388505 |
45 | Maternal diabetes (HP:0009800) | 2.04160501 |
46 | Intestinal atresia (HP:0011100) | 2.03076650 |
47 | Glioma (HP:0009733) | 2.02338231 |
48 | Agnosia (HP:0010524) | 2.02005851 |
49 | Biliary tract neoplasm (HP:0100574) | 2.01055729 |
50 | Optic nerve hypoplasia (HP:0000609) | 2.00959364 |
51 | Bifid tongue (HP:0010297) | 2.00636796 |
52 | Breast aplasia (HP:0100783) | 2.00109883 |
53 | Gonadotropin excess (HP:0000837) | 1.97599699 |
54 | Methylmalonic acidemia (HP:0002912) | 1.94266387 |
55 | Myelodysplasia (HP:0002863) | 1.94193790 |
56 | Homocystinuria (HP:0002156) | 1.94151776 |
57 | Abnormality of homocysteine metabolism (HP:0010919) | 1.94151776 |
58 | Sloping forehead (HP:0000340) | 1.94044893 |
59 | Reticulocytopenia (HP:0001896) | 1.90043018 |
60 | Triphalangeal thumb (HP:0001199) | 1.89588217 |
61 | Short middle phalanx of the 5th finger (HP:0004220) | 1.87766194 |
62 | Aqueductal stenosis (HP:0002410) | 1.87493951 |
63 | Abdominal situs inversus (HP:0003363) | 1.86699458 |
64 | Abnormality of abdominal situs (HP:0011620) | 1.86699458 |
65 | Aplastic anemia (HP:0001915) | 1.86347674 |
66 | Spastic diplegia (HP:0001264) | 1.85710297 |
67 | Horseshoe kidney (HP:0000085) | 1.85417496 |
68 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.85414319 |
69 | Median cleft lip (HP:0000161) | 1.84677160 |
70 | Hypoplastic female external genitalia (HP:0012815) | 1.84531061 |
71 | Hyperglycinemia (HP:0002154) | 1.83541274 |
72 | Gastrointestinal carcinoma (HP:0002672) | 1.83028351 |
73 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.83028351 |
74 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.82539136 |
75 | Astrocytoma (HP:0009592) | 1.82092802 |
76 | Abnormality of the astrocytes (HP:0100707) | 1.82092802 |
77 | Esophageal atresia (HP:0002032) | 1.77102479 |
78 | Neoplasm of the oral cavity (HP:0100649) | 1.76590323 |
79 | Neoplasm of the adrenal cortex (HP:0100641) | 1.76561121 |
80 | Hypoglycemic seizures (HP:0002173) | 1.76150798 |
81 | Labial hypoplasia (HP:0000066) | 1.76025617 |
82 | Small hand (HP:0200055) | 1.74601182 |
83 | Proximal placement of thumb (HP:0009623) | 1.74174478 |
84 | Choanal atresia (HP:0000453) | 1.73149369 |
85 | Neoplasm of the small intestine (HP:0100833) | 1.72816885 |
86 | Abnormality of serum amino acid levels (HP:0003112) | 1.72354634 |
87 | Sensory axonal neuropathy (HP:0003390) | 1.71179176 |
88 | Gastrointestinal atresia (HP:0002589) | 1.71063504 |
89 | Facial cleft (HP:0002006) | 1.70121060 |
90 | Cellular immunodeficiency (HP:0005374) | 1.68876299 |
91 | Neoplasm of striated muscle (HP:0009728) | 1.68141004 |
92 | Embryonal neoplasm (HP:0002898) | 1.67051322 |
93 | Hypoplastic labia majora (HP:0000059) | 1.65661594 |
94 | Uterine neoplasm (HP:0010784) | 1.65403356 |
95 | Pelvic girdle muscle weakness (HP:0003749) | 1.64444779 |
96 | Megaloblastic anemia (HP:0001889) | 1.63415685 |
97 | Hypoplastic pelvis (HP:0008839) | 1.63341509 |
98 | Deviation of the thumb (HP:0009603) | 1.63172686 |
99 | Thyroid carcinoma (HP:0002890) | 1.62768403 |
100 | Abnormal number of incisors (HP:0011064) | 1.62033263 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 3.60756535 |
2 | PNCK | 3.34784423 |
3 | BUB1 | 3.14797572 |
4 | TTK | 3.01951253 |
5 | TSSK6 | 2.99923720 |
6 | SRPK1 | 2.92640529 |
7 | MKNK2 | 2.91653561 |
8 | WEE1 | 2.67659439 |
9 | BRSK2 | 2.52426083 |
10 | TNIK | 2.34117396 |
11 | MKNK1 | 2.32909930 |
12 | PLK4 | 2.32348926 |
13 | TAF1 | 2.28630940 |
14 | TRIM28 | 2.22147982 |
15 | PLK3 | 2.21152773 |
16 | PBK | 2.11490434 |
17 | NUAK1 | 2.00757939 |
18 | EIF2AK3 | 1.98004662 |
19 | WNK3 | 1.95912079 |
20 | NEK1 | 1.84675241 |
21 | STK38L | 1.84041761 |
22 | BRD4 | 1.78691927 |
23 | MST4 | 1.75426007 |
24 | CDK19 | 1.65533530 |
25 | PLK1 | 1.62972276 |
26 | DYRK3 | 1.62901392 |
27 | ZAK | 1.62254999 |
28 | MAP3K10 | 1.55286622 |
29 | ERBB4 | 1.50553635 |
30 | VRK2 | 1.43799137 |
31 | STK3 | 1.42637550 |
32 | VRK1 | 1.38746293 |
33 | CASK | 1.37376353 |
34 | BCR | 1.33316247 |
35 | LATS1 | 1.29873312 |
36 | STK16 | 1.26646004 |
37 | NEK2 | 1.20315612 |
38 | CAMK1G | 1.19149255 |
39 | CHEK2 | 1.14516922 |
40 | ACVR1B | 1.10343548 |
41 | DYRK2 | 1.04002783 |
42 | CSNK1G1 | 1.02880670 |
43 | ATR | 1.01233490 |
44 | STK24 | 0.98151386 |
45 | CHEK1 | 0.89182049 |
46 | FGFR1 | 0.88808087 |
47 | ATM | 0.87484492 |
48 | NLK | 0.86941887 |
49 | BMPR1B | 0.85460492 |
50 | EIF2AK2 | 0.85011059 |
51 | ALK | 0.83623626 |
52 | AURKB | 0.83284637 |
53 | MAP3K4 | 0.78547670 |
54 | PASK | 0.77363303 |
55 | CDK3 | 0.76106018 |
56 | NME1 | 0.75773821 |
57 | BRSK1 | 0.75597156 |
58 | CSNK1G2 | 0.72759973 |
59 | YES1 | 0.72603597 |
60 | CDK7 | 0.71876934 |
61 | MAP3K9 | 0.70717569 |
62 | CDK12 | 0.66166154 |
63 | STK4 | 0.63690159 |
64 | CSNK1E | 0.62601330 |
65 | OXSR1 | 0.61847583 |
66 | EIF2AK1 | 0.61688889 |
67 | PLK2 | 0.59389371 |
68 | PDK2 | 0.58825686 |
69 | CDK2 | 0.57192995 |
70 | LATS2 | 0.56508626 |
71 | BRAF | 0.56460099 |
72 | DMPK | 0.56127639 |
73 | KSR1 | 0.55862094 |
74 | RPS6KA4 | 0.54186904 |
75 | CDK1 | 0.52958554 |
76 | FLT3 | 0.52481938 |
77 | MET | 0.51893948 |
78 | RAF1 | 0.50786445 |
79 | CSNK1G3 | 0.49767892 |
80 | MELK | 0.49133749 |
81 | AURKA | 0.49090557 |
82 | PIM1 | 0.47807907 |
83 | ERBB3 | 0.46032029 |
84 | CSNK1A1L | 0.45972504 |
85 | MAP2K7 | 0.45015399 |
86 | CDK6 | 0.43591160 |
87 | CLK1 | 0.43259822 |
88 | AKT3 | 0.42046310 |
89 | CSNK2A2 | 0.40156826 |
90 | CSNK2A1 | 0.38639162 |
91 | DYRK1A | 0.38404268 |
92 | PRKDC | 0.38354458 |
93 | MAP3K8 | 0.33014050 |
94 | MINK1 | 0.32377864 |
95 | EGFR | 0.31949120 |
96 | NEK6 | 0.27037341 |
97 | CDK9 | 0.26118419 |
98 | FGR | 0.24285848 |
99 | MAP4K2 | 0.24163771 |
100 | CAMK1D | 0.21892278 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Mismatch repair_Homo sapiens_hsa03430 | 4.05486438 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.62314372 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.58710664 |
4 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.18261704 |
5 | RNA transport_Homo sapiens_hsa03013 | 3.03477888 |
6 | Cell cycle_Homo sapiens_hsa04110 | 3.02811385 |
7 | Basal transcription factors_Homo sapiens_hsa03022 | 2.89886455 |
8 | Spliceosome_Homo sapiens_hsa03040 | 2.88587673 |
9 | Proteasome_Homo sapiens_hsa03050 | 2.77931737 |
10 | Homologous recombination_Homo sapiens_hsa03440 | 2.77740376 |
11 | RNA polymerase_Homo sapiens_hsa03020 | 2.61861824 |
12 | RNA degradation_Homo sapiens_hsa03018 | 2.53625753 |
13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.40025626 |
14 | Base excision repair_Homo sapiens_hsa03410 | 2.32277308 |
15 | Protein export_Homo sapiens_hsa03060 | 2.26882081 |
16 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.26667162 |
17 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.25064151 |
18 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.17657205 |
19 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.14001577 |
20 | Ribosome_Homo sapiens_hsa03010 | 1.77053204 |
21 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.73641270 |
22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.69994107 |
23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.66055458 |
24 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.63971514 |
25 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.56438185 |
26 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.55746149 |
27 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.53956165 |
28 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.45635898 |
29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.30724801 |
30 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.23356591 |
31 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.19813208 |
32 | Parkinsons disease_Homo sapiens_hsa05012 | 1.09053177 |
33 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.05930029 |
34 | Huntingtons disease_Homo sapiens_hsa05016 | 1.03676480 |
35 | Purine metabolism_Homo sapiens_hsa00230 | 0.99605614 |
36 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.98962785 |
37 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.95828126 |
38 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.94051811 |
39 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.92094758 |
40 | Adherens junction_Homo sapiens_hsa04520 | 0.89873508 |
41 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.89055984 |
42 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.81051240 |
43 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.81031262 |
44 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.78097983 |
45 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.77902160 |
46 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.76608176 |
47 | Thyroid cancer_Homo sapiens_hsa05216 | 0.75898040 |
48 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.72317414 |
49 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.68412728 |
50 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.67890986 |
51 | Colorectal cancer_Homo sapiens_hsa05210 | 0.66733305 |
52 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.63679028 |
53 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.58626993 |
54 | Prostate cancer_Homo sapiens_hsa05215 | 0.56690663 |
55 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.53069401 |
56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51394040 |
57 | Lysine degradation_Homo sapiens_hsa00310 | 0.47160527 |
58 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.43299542 |
59 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.42128056 |
60 | Alzheimers disease_Homo sapiens_hsa05010 | 0.41214181 |
61 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.40629726 |
62 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.40492146 |
63 | Tight junction_Homo sapiens_hsa04530 | 0.40154493 |
64 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.38834226 |
65 | Melanoma_Homo sapiens_hsa05218 | 0.37017659 |
66 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.35766920 |
67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34730396 |
68 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.33074069 |
69 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.32606046 |
70 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.32506187 |
71 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.31976861 |
72 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.31502730 |
73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.31013663 |
74 | Alcoholism_Homo sapiens_hsa05034 | 0.30168327 |
75 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.29682786 |
76 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.28720917 |
77 | Pathways in cancer_Homo sapiens_hsa05200 | 0.28501092 |
78 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.28100846 |
79 | Nicotine addiction_Homo sapiens_hsa05033 | 0.27653387 |
80 | Phototransduction_Homo sapiens_hsa04744 | 0.27135685 |
81 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.26656206 |
82 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.26345239 |
83 | Circadian rhythm_Homo sapiens_hsa04710 | 0.25934205 |
84 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.22984300 |
85 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.22008132 |
86 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.21921698 |
87 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.21808550 |
88 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.20144705 |
89 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.19847151 |
90 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.19745796 |
91 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.19578255 |
92 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.19213039 |
93 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.18947801 |
94 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.18527062 |
95 | Shigellosis_Homo sapiens_hsa05131 | 0.17426171 |
96 | Retinol metabolism_Homo sapiens_hsa00830 | 0.15882025 |
97 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.15206883 |
98 | Endometrial cancer_Homo sapiens_hsa05213 | 0.15153664 |
99 | Taste transduction_Homo sapiens_hsa04742 | 0.15020277 |
100 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.14555415 |