Rank | Gene Set | Z-score |
---|---|---|
1 | cellular protein complex localization (GO:0034629) | 5.34574718 |
2 | protein complex localization (GO:0031503) | 4.61041782 |
3 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 4.60322777 |
4 | DNA unwinding involved in DNA replication (GO:0006268) | 4.03162302 |
5 | apoptotic process involved in morphogenesis (GO:0060561) | 3.97590554 |
6 | adherens junction assembly (GO:0034333) | 3.79382741 |
7 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.79377731 |
8 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.79359864 |
9 | regulation of chromatin binding (GO:0035561) | 3.76098324 |
10 | mitotic chromosome condensation (GO:0007076) | 3.75587049 |
11 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.74650737 |
12 | protein retention in ER lumen (GO:0006621) | 3.71948118 |
13 | heterochromatin organization (GO:0070828) | 3.71297547 |
14 | regulation of translational fidelity (GO:0006450) | 3.62984480 |
15 | proline biosynthetic process (GO:0006561) | 3.60650392 |
16 | Golgi transport vesicle coating (GO:0048200) | 3.55035536 |
17 | COPI coating of Golgi vesicle (GO:0048205) | 3.55035536 |
18 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.54794450 |
19 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.49695578 |
20 | focal adhesion assembly (GO:0048041) | 3.48397075 |
21 | cell-substrate adherens junction assembly (GO:0007045) | 3.48397075 |
22 | activation of Rac GTPase activity (GO:0032863) | 3.43402288 |
23 | nuclear pore complex assembly (GO:0051292) | 3.41679701 |
24 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.41423065 |
25 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.37087440 |
26 | protein localization to endosome (GO:0036010) | 3.35111656 |
27 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 3.32827002 |
28 | regulation of early endosome to late endosome transport (GO:2000641) | 3.19815700 |
29 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 3.17906099 |
30 | regulation of RNA export from nucleus (GO:0046831) | 3.14645101 |
31 | negative regulation of cell size (GO:0045792) | 3.12642836 |
32 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.11611235 |
33 | lymph vessel development (GO:0001945) | 3.07865494 |
34 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.06952625 |
35 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 3.05383010 |
36 | maternal placenta development (GO:0001893) | 3.05128385 |
37 | cell-substrate junction assembly (GO:0007044) | 3.03344625 |
38 | peptidyl-arginine methylation (GO:0018216) | 3.02852454 |
39 | peptidyl-arginine N-methylation (GO:0035246) | 3.02852454 |
40 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 3.01755469 |
41 | histone arginine methylation (GO:0034969) | 3.00419383 |
42 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.96838702 |
43 | DNA replication initiation (GO:0006270) | 2.96150678 |
44 | negative regulation of viral release from host cell (GO:1902187) | 2.90146337 |
45 | protein-DNA complex disassembly (GO:0032986) | 2.89569982 |
46 | nucleosome disassembly (GO:0006337) | 2.89569982 |
47 | peptidyl-lysine dimethylation (GO:0018027) | 2.89517717 |
48 | atrioventricular valve morphogenesis (GO:0003181) | 2.89053341 |
49 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.88621644 |
50 | pentose-phosphate shunt (GO:0006098) | 2.86028821 |
51 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 2.85879740 |
52 | basement membrane organization (GO:0071711) | 2.83248408 |
53 | desmosome organization (GO:0002934) | 2.83091612 |
54 | mRNA stabilization (GO:0048255) | 2.82792136 |
55 | RNA stabilization (GO:0043489) | 2.82792136 |
56 | embryonic process involved in female pregnancy (GO:0060136) | 2.79297942 |
57 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.78197742 |
58 | chromatin assembly (GO:0031497) | 2.76898759 |
59 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.76281037 |
60 | nuclear pore organization (GO:0006999) | 2.73615053 |
61 | epithelial cell-cell adhesion (GO:0090136) | 2.73282819 |
62 | DNA strand elongation (GO:0022616) | 2.72623455 |
63 | ribosomal small subunit biogenesis (GO:0042274) | 2.72445345 |
64 | regulation of translational termination (GO:0006449) | 2.70963069 |
65 | snRNA metabolic process (GO:0016073) | 2.66434424 |
66 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.64646180 |
67 | semaphorin-plexin signaling pathway (GO:0071526) | 2.64005057 |
68 | mitotic sister chromatid segregation (GO:0000070) | 2.63712696 |
69 | hemidesmosome assembly (GO:0031581) | 2.61794341 |
70 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.61487396 |
71 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.61165243 |
72 | trophectodermal cell differentiation (GO:0001829) | 2.59955350 |
73 | apoptotic process involved in development (GO:1902742) | 2.59262711 |
74 | activation of MAPKKK activity (GO:0000185) | 2.56765659 |
75 | glucose catabolic process (GO:0006007) | 2.56733654 |
76 | nuclear envelope reassembly (GO:0031468) | 2.56624605 |
77 | mitotic nuclear envelope reassembly (GO:0007084) | 2.56624605 |
78 | pore complex assembly (GO:0046931) | 2.55053818 |
79 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.51874965 |
80 | trophoblast giant cell differentiation (GO:0060707) | 2.49073324 |
81 | convergent extension (GO:0060026) | 2.48684047 |
82 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.47201971 |
83 | embryonic eye morphogenesis (GO:0048048) | 2.47144295 |
84 | diaphragm development (GO:0060539) | 2.46469539 |
85 | dosage compensation (GO:0007549) | 2.46440799 |
86 | mammary gland epithelial cell differentiation (GO:0060644) | 2.46396128 |
87 | cell-cell junction maintenance (GO:0045217) | 2.45300016 |
88 | positive regulation of histone deacetylation (GO:0031065) | 2.44954890 |
89 | negative regulation of mRNA processing (GO:0050686) | 2.44031092 |
90 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059) | 2.43365669 |
91 | negative regulation of mRNA metabolic process (GO:1903312) | 2.43311949 |
92 | folic acid metabolic process (GO:0046655) | 2.43123018 |
93 | modulation by symbiont of host cellular process (GO:0044068) | 2.42806866 |
94 | L-serine metabolic process (GO:0006563) | 2.42355283 |
95 | protein localization to microtubule (GO:0035372) | 2.42282683 |
96 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 2.41786134 |
97 | negative regulation of fatty acid transport (GO:2000192) | 2.41402197 |
98 | establishment of apical/basal cell polarity (GO:0035089) | 2.41311112 |
99 | G1 DNA damage checkpoint (GO:0044783) | 2.39845932 |
100 | mitotic G1/S transition checkpoint (GO:0044819) | 2.39844080 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.21571802 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.26867725 |
3 | * MYC_22102868_ChIP-Seq_BL_Human | 2.97316516 |
4 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.72158313 |
5 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.45391180 |
6 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.40111248 |
7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.39410867 |
8 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.38027823 |
9 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.35294077 |
10 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.28588075 |
11 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.24270876 |
12 | RACK7_27058665_Chip-Seq_MCF-7_Human | 2.15204421 |
13 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.08120651 |
14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.07489706 |
15 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.04616840 |
16 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.94080882 |
17 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.91867615 |
18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.90934217 |
19 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.89956229 |
20 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.88716410 |
21 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.86405503 |
22 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.85804100 |
23 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.85695216 |
24 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.84164152 |
25 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.76933756 |
26 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.76267721 |
27 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.74516476 |
28 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.72027472 |
29 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.70632200 |
30 | KDM2B_26808549_Chip-Seq_K562_Human | 1.67659389 |
31 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.64674796 |
32 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.57419701 |
33 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.53991934 |
34 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.53244318 |
35 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.52324363 |
36 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.48804256 |
37 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.47743687 |
38 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.45829483 |
39 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.44836394 |
40 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.44379233 |
41 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.44141010 |
42 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.43910228 |
43 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.43299969 |
44 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.41530208 |
45 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.40775582 |
46 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.38151818 |
47 | P68_20966046_ChIP-Seq_HELA_Human | 1.36989699 |
48 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.35511953 |
49 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.34484339 |
50 | ATF3_27146783_Chip-Seq_COLON_Human | 1.31309388 |
51 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.29985105 |
52 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.29828740 |
53 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.29811538 |
54 | * NCOR1_26117541_ChIP-Seq_K562_Human | 1.29162473 |
55 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.28619435 |
56 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.27572108 |
57 | MAF_26560356_Chip-Seq_TH1_Human | 1.27551397 |
58 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.26088314 |
59 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.24536948 |
60 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.23843171 |
61 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.23461849 |
62 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.23325699 |
63 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.23196636 |
64 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.22994285 |
65 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.22013396 |
66 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.20846278 |
67 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.20615330 |
68 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.18910323 |
69 | MAF_26560356_Chip-Seq_TH2_Human | 1.16509584 |
70 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.14921904 |
71 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.12762220 |
72 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.12063446 |
73 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.11494462 |
74 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.11455064 |
75 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.11361258 |
76 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.11286433 |
77 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.10732869 |
78 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.09514370 |
79 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.09454420 |
80 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.08988899 |
81 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.08387298 |
82 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.07398655 |
83 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.06119846 |
84 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.06004808 |
85 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.05816390 |
86 | UTX_26944678_Chip-Seq_JUKART_Human | 1.04693734 |
87 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.04499594 |
88 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.04401681 |
89 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03581207 |
90 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02230200 |
91 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.01082603 |
92 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.00719399 |
93 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.99870457 |
94 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.99841928 |
95 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.98872081 |
96 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.98157423 |
97 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.97148805 |
98 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.97067197 |
99 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.95874901 |
100 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.95230582 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 5.21978632 |
2 | MP0005076_abnormal_cell_differentiation | 2.84657915 |
3 | MP0002877_abnormal_melanocyte_morpholog | 2.56638591 |
4 | MP0004185_abnormal_adipocyte_glucose | 2.55415836 |
5 | MP0005451_abnormal_body_composition | 2.54930292 |
6 | MP0003111_abnormal_nucleus_morphology | 2.29274642 |
7 | MP0002249_abnormal_larynx_morphology | 2.26878669 |
8 | MP0000678_abnormal_parathyroid_gland | 2.20671091 |
9 | MP0005623_abnormal_meninges_morphology | 2.20157487 |
10 | MP0008438_abnormal_cutaneous_collagen | 2.15731552 |
11 | MP0000537_abnormal_urethra_morphology | 2.12384895 |
12 | MP0001849_ear_inflammation | 2.10550334 |
13 | MP0003693_abnormal_embryo_hatching | 2.09557677 |
14 | MP0004858_abnormal_nervous_system | 2.00639419 |
15 | MP0005409_darkened_coat_color | 1.98068290 |
16 | MP0010234_abnormal_vibrissa_follicle | 1.93090062 |
17 | MP0003453_abnormal_keratinocyte_physiol | 1.91496427 |
18 | MP0010352_gastrointestinal_tract_polyps | 1.89376338 |
19 | MP0010030_abnormal_orbit_morphology | 1.89058867 |
20 | MP0003566_abnormal_cell_adhesion | 1.87311459 |
21 | MP0002796_impaired_skin_barrier | 1.85462987 |
22 | MP0005058_abnormal_lysosome_morphology | 1.83253888 |
23 | MP0001730_embryonic_growth_arrest | 1.75469680 |
24 | MP0009053_abnormal_anal_canal | 1.67527047 |
25 | MP0001346_abnormal_lacrimal_gland | 1.60738451 |
26 | MP0004272_abnormal_basement_membrane | 1.60362024 |
27 | MP0004957_abnormal_blastocyst_morpholog | 1.56241511 |
28 | MP0005501_abnormal_skin_physiology | 1.55689892 |
29 | MP0003077_abnormal_cell_cycle | 1.52650550 |
30 | MP0009278_abnormal_bone_marrow | 1.52351548 |
31 | MP0004233_abnormal_muscle_weight | 1.50297188 |
32 | MP0000350_abnormal_cell_proliferation | 1.46929128 |
33 | MP0005666_abnormal_adipose_tissue | 1.43889630 |
34 | MP0000733_abnormal_muscle_development | 1.42783793 |
35 | MP0000003_abnormal_adipose_tissue | 1.40226500 |
36 | MP0009672_abnormal_birth_weight | 1.39168144 |
37 | MP0003942_abnormal_urinary_system | 1.34349389 |
38 | MP0002089_abnormal_postnatal_growth/wei | 1.33957360 |
39 | MP0005375_adipose_tissue_phenotype | 1.33038323 |
40 | MP0008260_abnormal_autophagy | 1.28969217 |
41 | MP0002060_abnormal_skin_morphology | 1.28602164 |
42 | MP0003091_abnormal_cell_migration | 1.28151533 |
43 | MP0002009_preneoplasia | 1.26459050 |
44 | MP0010094_abnormal_chromosome_stability | 1.26085180 |
45 | MP0008932_abnormal_embryonic_tissue | 1.22918633 |
46 | MP0002396_abnormal_hematopoietic_system | 1.22041733 |
47 | MP0009840_abnormal_foam_cell | 1.21987920 |
48 | MP0000566_synostosis | 1.18620158 |
49 | MP0001672_abnormal_embryogenesis/_devel | 1.17028611 |
50 | MP0005380_embryogenesis_phenotype | 1.17028611 |
51 | MP0002080_prenatal_lethality | 1.16811259 |
52 | MP0003984_embryonic_growth_retardation | 1.15882728 |
53 | MP0002697_abnormal_eye_size | 1.13090797 |
54 | MP0002085_abnormal_embryonic_tissue | 1.12575663 |
55 | MP0004808_abnormal_hematopoietic_stem | 1.12289162 |
56 | MP0002086_abnormal_extraembryonic_tissu | 1.11741730 |
57 | MP0000579_abnormal_nail_morphology | 1.10789965 |
58 | MP0002088_abnormal_embryonic_growth/wei | 1.08574741 |
59 | MP0009333_abnormal_splenocyte_physiolog | 1.08452095 |
60 | MP0001216_abnormal_epidermal_layer | 1.06996626 |
61 | MP0005257_abnormal_intraocular_pressure | 1.06831766 |
62 | MP0001348_abnormal_lacrimal_gland | 1.04186476 |
63 | MP0000490_abnormal_crypts_of | 1.03988672 |
64 | MP0003303_peritoneal_inflammation | 1.01786241 |
65 | MP0003115_abnormal_respiratory_system | 1.00065741 |
66 | MP0002098_abnormal_vibrissa_morphology | 0.99788893 |
67 | MP0004947_skin_inflammation | 0.99495005 |
68 | MP0009931_abnormal_skin_appearance | 0.97993638 |
69 | MP0001697_abnormal_embryo_size | 0.96355159 |
70 | MP0010307_abnormal_tumor_latency | 0.95960609 |
71 | MP0003941_abnormal_skin_development | 0.95408880 |
72 | MP0000313_abnormal_cell_death | 0.95113168 |
73 | MP0005621_abnormal_cell_physiology | 0.93297340 |
74 | MP0003315_abnormal_perineum_morphology | 0.92726993 |
75 | MP0004264_abnormal_extraembryonic_tissu | 0.92133408 |
76 | MP0002092_abnormal_eye_morphology | 0.91615229 |
77 | MP0000428_abnormal_craniofacial_morphol | 0.91562389 |
78 | MP0000762_abnormal_tongue_morphology | 0.89962771 |
79 | MP0001915_intracranial_hemorrhage | 0.89728745 |
80 | MP0010630_abnormal_cardiac_muscle | 0.89669599 |
81 | MP0000858_altered_metastatic_potential | 0.89587924 |
82 | MP0000534_abnormal_ureter_morphology | 0.89303616 |
83 | MP0002084_abnormal_developmental_patter | 0.88104998 |
84 | MP0000467_abnormal_esophagus_morphology | 0.87524357 |
85 | MP0000759_abnormal_skeletal_muscle | 0.87191435 |
86 | MP0003123_paternal_imprinting | 0.83630878 |
87 | MP0005023_abnormal_wound_healing | 0.82233594 |
88 | MP0008007_abnormal_cellular_replicative | 0.81592664 |
89 | MP0000767_abnormal_smooth_muscle | 0.80599879 |
90 | MP0004197_abnormal_fetal_growth/weight/ | 0.79440422 |
91 | MP0003279_aneurysm | 0.79118727 |
92 | MP0002925_abnormal_cardiovascular_devel | 0.77840999 |
93 | MP0005508_abnormal_skeleton_morphology | 0.77637336 |
94 | MP0000377_abnormal_hair_follicle | 0.77538352 |
95 | MP0009384_cardiac_valve_regurgitation | 0.77091303 |
96 | MP0000681_abnormal_thyroid_gland | 0.75684473 |
97 | MP0003385_abnormal_body_wall | 0.73941965 |
98 | MP0002114_abnormal_axial_skeleton | 0.73380419 |
99 | MP0003172_abnormal_lysosome_physiology | 0.73312531 |
100 | MP0001340_abnormal_eyelid_morphology | 0.69775150 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Hyperacusis (HP:0010780) | 3.83233793 |
2 | Ulnar bowing (HP:0003031) | 3.02803808 |
3 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.80236627 |
4 | Disproportionate tall stature (HP:0001519) | 2.74101755 |
5 | Protrusio acetabuli (HP:0003179) | 2.73476869 |
6 | Broad distal phalanx of finger (HP:0009836) | 2.71700274 |
7 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.64963680 |
8 | Achilles tendon contracture (HP:0001771) | 2.58074188 |
9 | Distal lower limb amyotrophy (HP:0008944) | 2.54698091 |
10 | Septate vagina (HP:0001153) | 2.47068189 |
11 | Increased connective tissue (HP:0009025) | 2.45844898 |
12 | Broad face (HP:0000283) | 2.44278082 |
13 | Long palpebral fissure (HP:0000637) | 2.44142776 |
14 | Premature rupture of membranes (HP:0001788) | 2.43422414 |
15 | Insomnia (HP:0100785) | 2.40458064 |
16 | Progressive muscle weakness (HP:0003323) | 2.39188459 |
17 | Biconcave vertebral bodies (HP:0004586) | 2.38645143 |
18 | Asymmetry of the thorax (HP:0001555) | 2.37171763 |
19 | Cerebral aneurysm (HP:0004944) | 2.36446193 |
20 | Obstructive sleep apnea (HP:0002870) | 2.34693008 |
21 | Shallow orbits (HP:0000586) | 2.34043571 |
22 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.33435459 |
23 | Trismus (HP:0000211) | 2.32530165 |
24 | Vertebral compression fractures (HP:0002953) | 2.30877640 |
25 | Truncus arteriosus (HP:0001660) | 2.23068718 |
26 | Selective tooth agenesis (HP:0001592) | 2.22072256 |
27 | Abnormality of the Achilles tendon (HP:0005109) | 2.21617686 |
28 | Distal upper limb amyotrophy (HP:0007149) | 2.20561647 |
29 | Upper limb amyotrophy (HP:0009129) | 2.20561647 |
30 | Nonimmune hydrops fetalis (HP:0001790) | 2.13303630 |
31 | Fragile skin (HP:0001030) | 2.13150198 |
32 | Abnormality of the fingertips (HP:0001211) | 2.12502761 |
33 | High anterior hairline (HP:0009890) | 2.06720746 |
34 | Patellar dislocation (HP:0002999) | 2.04755119 |
35 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.04710865 |
36 | Thin bony cortex (HP:0002753) | 2.02477629 |
37 | Abnormality of the thoracic spine (HP:0100711) | 2.02427953 |
38 | Abnormality of the umbilical cord (HP:0010881) | 2.00541841 |
39 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.00430246 |
40 | Single umbilical artery (HP:0001195) | 2.00430246 |
41 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.00430246 |
42 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.99206075 |
43 | Ankyloglossia (HP:0010296) | 1.98580246 |
44 | Bowel incontinence (HP:0002607) | 1.97825465 |
45 | Hypercalcemia (HP:0003072) | 1.96922544 |
46 | Advanced eruption of teeth (HP:0006288) | 1.96715581 |
47 | Spinal cord lesions (HP:0100561) | 1.96100152 |
48 | Syringomyelia (HP:0003396) | 1.96100152 |
49 | Overriding aorta (HP:0002623) | 1.95477088 |
50 | Breast hypoplasia (HP:0003187) | 1.94290211 |
51 | Abnormal large intestine physiology (HP:0012700) | 1.91419853 |
52 | Pointed chin (HP:0000307) | 1.89593827 |
53 | Abnormality of the aortic arch (HP:0012303) | 1.89140916 |
54 | Elfin facies (HP:0004428) | 1.88513587 |
55 | Genu recurvatum (HP:0002816) | 1.87753384 |
56 | Natal tooth (HP:0000695) | 1.87562191 |
57 | Dysmetric saccades (HP:0000641) | 1.85583573 |
58 | Stridor (HP:0010307) | 1.85549239 |
59 | Increased variability in muscle fiber diameter (HP:0003557) | 1.85274080 |
60 | Flat acetabular roof (HP:0003180) | 1.85163440 |
61 | Germ cell neoplasia (HP:0100728) | 1.84892153 |
62 | Mitral regurgitation (HP:0001653) | 1.83846756 |
63 | Abnormality of the calcaneus (HP:0008364) | 1.83823490 |
64 | Hyperparathyroidism (HP:0000843) | 1.82473013 |
65 | Premature skin wrinkling (HP:0100678) | 1.81315761 |
66 | Short nail (HP:0001799) | 1.80561702 |
67 | Spinal rigidity (HP:0003306) | 1.80531036 |
68 | Abnormal connection of the cardiac segments (HP:0011545) | 1.78700203 |
69 | Abnormal ventriculo-arterial connection (HP:0011563) | 1.78700203 |
70 | Transposition of the great arteries (HP:0001669) | 1.78700203 |
71 | Hypertensive crisis (HP:0100735) | 1.78398197 |
72 | Arnold-Chiari malformation (HP:0002308) | 1.77433649 |
73 | Renal duplication (HP:0000075) | 1.77028536 |
74 | Abnormality of oral frenula (HP:0000190) | 1.71635083 |
75 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.71432652 |
76 | Deep palmar crease (HP:0006191) | 1.69870900 |
77 | Blue sclerae (HP:0000592) | 1.69582545 |
78 | Lower limb amyotrophy (HP:0007210) | 1.69031035 |
79 | Bladder diverticulum (HP:0000015) | 1.68592596 |
80 | Deviation of the thumb (HP:0009603) | 1.66927791 |
81 | Distal lower limb muscle weakness (HP:0009053) | 1.66229362 |
82 | Myopathic facies (HP:0002058) | 1.65877948 |
83 | Generalized amyotrophy (HP:0003700) | 1.65591102 |
84 | Sparse lateral eyebrow (HP:0005338) | 1.65347290 |
85 | J-shaped sella turcica (HP:0002680) | 1.64985757 |
86 | Abnormality of the columella (HP:0009929) | 1.63978431 |
87 | Pseudobulbar signs (HP:0002200) | 1.63101285 |
88 | Hand muscle atrophy (HP:0009130) | 1.63082016 |
89 | Cholecystitis (HP:0001082) | 1.62420522 |
90 | Abnormal gallbladder physiology (HP:0012438) | 1.62420522 |
91 | Metaphyseal cupping (HP:0003021) | 1.61338650 |
92 | Long eyelashes (HP:0000527) | 1.60546308 |
93 | Cervical subluxation (HP:0003308) | 1.60341855 |
94 | Mitral valve prolapse (HP:0001634) | 1.60156631 |
95 | Atrophic scars (HP:0001075) | 1.59688858 |
96 | Increased nuchal translucency (HP:0010880) | 1.59686272 |
97 | Abnormality of the salivary glands (HP:0010286) | 1.58954287 |
98 | Elbow flexion contracture (HP:0002987) | 1.58566576 |
99 | Short clavicles (HP:0000894) | 1.58261510 |
100 | Multiple enchondromatosis (HP:0005701) | 1.57370835 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 5.12477417 |
2 | SMG1 | 4.74317405 |
3 | EEF2K | 3.98513364 |
4 | CDK12 | 3.19179792 |
5 | ICK | 3.15815741 |
6 | PRPF4B | 3.03730603 |
7 | SIK1 | 3.00989853 |
8 | IRAK3 | 2.96233010 |
9 | MAP3K10 | 2.59126227 |
10 | NME2 | 2.24073676 |
11 | ERN1 | 1.97652312 |
12 | RIPK1 | 1.96924021 |
13 | EPHA2 | 1.78933773 |
14 | PKN2 | 1.62590234 |
15 | VRK2 | 1.59433721 |
16 | TTN | 1.50373962 |
17 | PDGFRA | 1.36820792 |
18 | TAOK2 | 1.35147373 |
19 | MTOR | 1.32984303 |
20 | MAP2K3 | 1.23778538 |
21 | FGFR4 | 1.16140825 |
22 | PAK4 | 1.15691187 |
23 | CDK7 | 1.12390993 |
24 | MAP3K8 | 1.09812273 |
25 | CAMK1D | 1.09663903 |
26 | ARAF | 1.08856613 |
27 | BRAF | 1.02813025 |
28 | KSR2 | 1.00588610 |
29 | MARK2 | 0.99759897 |
30 | RPS6KB2 | 0.98289797 |
31 | CDC7 | 0.97512001 |
32 | PTK6 | 0.97286396 |
33 | MST1R | 0.95990140 |
34 | CHEK2 | 0.93839667 |
35 | PRKD3 | 0.92951821 |
36 | LATS2 | 0.90449580 |
37 | CDK4 | 0.90241859 |
38 | RPS6KC1 | 0.89953819 |
39 | RPS6KL1 | 0.89953819 |
40 | BUB1 | 0.89702776 |
41 | TYRO3 | 0.86639006 |
42 | MAP3K11 | 0.86192613 |
43 | RPS6KA2 | 0.86065811 |
44 | PIM2 | 0.85685974 |
45 | IRAK2 | 0.84510078 |
46 | BRD4 | 0.83045703 |
47 | IRAK4 | 0.79930451 |
48 | PTK2 | 0.79375435 |
49 | HIPK2 | 0.79062756 |
50 | TAOK1 | 0.78148090 |
51 | MAP3K13 | 0.77375969 |
52 | CAMK1G | 0.75629134 |
53 | PRKD2 | 0.74983208 |
54 | CLK1 | 0.73376958 |
55 | MAP3K1 | 0.72750954 |
56 | KDR | 0.70703557 |
57 | MAPK11 | 0.68231081 |
58 | RPS6KA6 | 0.65298799 |
59 | AURKA | 0.64226385 |
60 | MAP3K3 | 0.63857717 |
61 | TAF1 | 0.63421720 |
62 | BMX | 0.62140952 |
63 | CDC42BPA | 0.61710094 |
64 | MAP2K2 | 0.60225082 |
65 | PDPK1 | 0.54495604 |
66 | CHEK1 | 0.53330859 |
67 | TTK | 0.52065631 |
68 | NTRK1 | 0.51239361 |
69 | TESK2 | 0.50146978 |
70 | DDR2 | 0.49439675 |
71 | CDK6 | 0.49413993 |
72 | BLK | 0.49294792 |
73 | LMTK2 | 0.49227251 |
74 | RPS6KA1 | 0.47788111 |
75 | NEK2 | 0.44762465 |
76 | AKT2 | 0.44581677 |
77 | ILK | 0.43480408 |
78 | STK4 | 0.42993628 |
79 | LRRK2 | 0.42014863 |
80 | CDK9 | 0.41217884 |
81 | PDGFRB | 0.40287353 |
82 | MAP3K9 | 0.39261287 |
83 | CDK8 | 0.38437200 |
84 | SIK2 | 0.38387447 |
85 | ALK | 0.38133428 |
86 | RAF1 | 0.37608692 |
87 | EPHB2 | 0.37285624 |
88 | CDK2 | 0.36587630 |
89 | TBK1 | 0.36367552 |
90 | ATR | 0.35912462 |
91 | MAP3K6 | 0.35261446 |
92 | DMPK | 0.35106235 |
93 | MET | 0.34253715 |
94 | TESK1 | 0.33507538 |
95 | EPHB1 | 0.31321304 |
96 | PAK2 | 0.30507640 |
97 | CDK1 | 0.29801066 |
98 | EIF2AK2 | 0.29495587 |
99 | DAPK3 | 0.29108588 |
100 | SGK3 | 0.27301117 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 2.48850809 |
2 | DNA replication_Homo sapiens_hsa03030 | 2.40252468 |
3 | Bladder cancer_Homo sapiens_hsa05219 | 2.29766810 |
4 | Notch signaling pathway_Homo sapiens_hsa04330 | 2.18741079 |
5 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 2.15592238 |
6 | Sulfur relay system_Homo sapiens_hsa04122 | 2.11462638 |
7 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.98875818 |
8 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.93870506 |
9 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.87480079 |
10 | Other glycan degradation_Homo sapiens_hsa00511 | 1.77286278 |
11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.76805002 |
12 | Thyroid cancer_Homo sapiens_hsa05216 | 1.74694775 |
13 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.61840752 |
14 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.58821191 |
15 | Endometrial cancer_Homo sapiens_hsa05213 | 1.58158879 |
16 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.52358114 |
17 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.48603788 |
18 | Base excision repair_Homo sapiens_hsa03410 | 1.36019841 |
19 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.36003770 |
20 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.35390508 |
21 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.35307993 |
22 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.34680106 |
23 | Glioma_Homo sapiens_hsa05214 | 1.34476925 |
24 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.33997950 |
25 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.33018905 |
26 | Cell cycle_Homo sapiens_hsa04110 | 1.29825880 |
27 | Prion diseases_Homo sapiens_hsa05020 | 1.28692291 |
28 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.26903371 |
29 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.26299084 |
30 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.25686260 |
31 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 1.25026021 |
32 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.23043070 |
33 | Lysine degradation_Homo sapiens_hsa00310 | 1.22672572 |
34 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.21329862 |
35 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.20816151 |
36 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.19923684 |
37 | Prostate cancer_Homo sapiens_hsa05215 | 1.16654162 |
38 | Colorectal cancer_Homo sapiens_hsa05210 | 1.12133731 |
39 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 1.10311355 |
40 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.09439302 |
41 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.04399540 |
42 | Spliceosome_Homo sapiens_hsa03040 | 1.04237005 |
43 | Apoptosis_Homo sapiens_hsa04210 | 1.03924651 |
44 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.03166719 |
45 | Galactose metabolism_Homo sapiens_hsa00052 | 1.01398500 |
46 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.00688994 |
47 | Hepatitis B_Homo sapiens_hsa05161 | 0.99830355 |
48 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.99758768 |
49 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.99309315 |
50 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.99002567 |
51 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.98985920 |
52 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.98350770 |
53 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.94049307 |
54 | HTLV-I infection_Homo sapiens_hsa05166 | 0.93869669 |
55 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.91228438 |
56 | Focal adhesion_Homo sapiens_hsa04510 | 0.89508416 |
57 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.88558343 |
58 | Adherens junction_Homo sapiens_hsa04520 | 0.88303599 |
59 | Hepatitis C_Homo sapiens_hsa05160 | 0.87931041 |
60 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84804586 |
61 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.84376533 |
62 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.83255218 |
63 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.79794363 |
64 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.77930789 |
65 | Carbon metabolism_Homo sapiens_hsa01200 | 0.74770096 |
66 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.74355452 |
67 | Alcoholism_Homo sapiens_hsa05034 | 0.73773594 |
68 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.73434214 |
69 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.72258742 |
70 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.71086680 |
71 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.70922034 |
72 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.70226346 |
73 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.69696677 |
74 | Melanoma_Homo sapiens_hsa05218 | 0.68661179 |
75 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.68591661 |
76 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.68084402 |
77 | Mismatch repair_Homo sapiens_hsa03430 | 0.67772837 |
78 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.67459733 |
79 | Insulin resistance_Homo sapiens_hsa04931 | 0.66857878 |
80 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.66276975 |
81 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.65876282 |
82 | Influenza A_Homo sapiens_hsa05164 | 0.64550096 |
83 | RNA transport_Homo sapiens_hsa03013 | 0.61200147 |
84 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.61196937 |
85 | Pathways in cancer_Homo sapiens_hsa05200 | 0.61122235 |
86 | Shigellosis_Homo sapiens_hsa05131 | 0.60726368 |
87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.59756651 |
88 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.59707424 |
89 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.58744504 |
90 | Amoebiasis_Homo sapiens_hsa05146 | 0.58587090 |
91 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.55358354 |
92 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.54302856 |
93 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.54257857 |
94 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.54002166 |
95 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.53606354 |
96 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.52883080 |
97 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.52335921 |
98 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.51883932 |
99 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.51022242 |
100 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.50583568 |