ZNF32

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein complex biogenesis (GO:0070271)4.07974659
2positive regulation of mitochondrial fission (GO:0090141)3.88332601
3mitochondrial respiratory chain complex assembly (GO:0033108)3.87638938
4mitochondrial respiratory chain complex I assembly (GO:0032981)3.86977994
5NADH dehydrogenase complex assembly (GO:0010257)3.86977994
6mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.86977994
7pyrimidine nucleobase catabolic process (GO:0006208)3.71871460
8metallo-sulfur cluster assembly (GO:0031163)3.61679161
9iron-sulfur cluster assembly (GO:0016226)3.61679161
10inositol phosphate catabolic process (GO:0071545)3.55553914
11intraciliary transport (GO:0042073)3.54840247
12ubiquinone biosynthetic process (GO:0006744)3.47124299
13respiratory chain complex IV assembly (GO:0008535)3.43810436
14protein polyglutamylation (GO:0018095)3.37253966
15mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.37113413
16gamma-aminobutyric acid transport (GO:0015812)3.31294738
17water-soluble vitamin biosynthetic process (GO:0042364)3.30835832
18peptidyl-histidine modification (GO:0018202)3.30426783
19cullin deneddylation (GO:0010388)3.23915590
20ubiquinone metabolic process (GO:0006743)3.21363638
21anterograde synaptic vesicle transport (GO:0048490)3.18988467
22mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.18735732
23nonmotile primary cilium assembly (GO:0035058)3.15815159
24peroxisome fission (GO:0016559)3.12382890
25platelet dense granule organization (GO:0060155)3.11884035
26response to pheromone (GO:0019236)3.11058187
27chaperone-mediated protein transport (GO:0072321)3.09371767
28establishment of mitochondrion localization (GO:0051654)3.07565239
29nucleobase catabolic process (GO:0046113)3.06379927
30presynaptic membrane assembly (GO:0097105)3.02839725
31cytochrome complex assembly (GO:0017004)2.95890755
32regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.94029270
33postsynaptic membrane organization (GO:0001941)2.93882427
34regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.93085417
35respiratory electron transport chain (GO:0022904)2.89564726
36electron transport chain (GO:0022900)2.89089227
37RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.88652396
38tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.88652396
39negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.86795975
40negative regulation of cytosolic calcium ion concentration (GO:0051481)2.84351808
41regulation of cilium movement (GO:0003352)2.82387509
42protein deneddylation (GO:0000338)2.81454589
43branched-chain amino acid catabolic process (GO:0009083)2.79811148
44behavioral response to nicotine (GO:0035095)2.78607946
45negative regulation of synaptic transmission, GABAergic (GO:0032229)2.77740790
46quinone biosynthetic process (GO:1901663)2.77649315
47protein neddylation (GO:0045116)2.77558724
48ATP synthesis coupled proton transport (GO:0015986)2.77250737
49energy coupled proton transport, down electrochemical gradient (GO:0015985)2.77250737
50regulation of mitochondrial translation (GO:0070129)2.77148295
51regulation of cofactor metabolic process (GO:0051193)2.76606280
52regulation of coenzyme metabolic process (GO:0051196)2.76606280
53short-chain fatty acid metabolic process (GO:0046459)2.75380902
54L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.74337970
55presynaptic membrane organization (GO:0097090)2.73855317
56positive regulation of TOR signaling (GO:0032008)2.69430957
57regulation of acyl-CoA biosynthetic process (GO:0050812)2.69032600
58regulation of glucokinase activity (GO:0033131)2.66799006
59regulation of hexokinase activity (GO:1903299)2.66799006
60protein localization to cilium (GO:0061512)2.66537879
61proteasome assembly (GO:0043248)2.66232196
62base-excision repair, AP site formation (GO:0006285)2.65420208
63regulation of short-term neuronal synaptic plasticity (GO:0048172)2.64668447
64epithelial cilium movement (GO:0003351)2.63272823
65histone H2A acetylation (GO:0043968)2.63237944
66synaptic vesicle maturation (GO:0016188)2.62861702
67neuromuscular synaptic transmission (GO:0007274)2.61789343
68positive regulation of amino acid transport (GO:0051957)2.61714086
69synaptic transmission, cholinergic (GO:0007271)2.60943651
70neuron cell-cell adhesion (GO:0007158)2.59165809
71positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.59155189
72GMP metabolic process (GO:0046037)2.58325681
73piRNA metabolic process (GO:0034587)2.56784756
74vascular smooth muscle contraction (GO:0014829)2.55193014
75aldehyde catabolic process (GO:0046185)2.52901418
76membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.52477478
77anterograde axon cargo transport (GO:0008089)2.49324474
78single strand break repair (GO:0000012)2.48540611
79positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.47974503
80hyperosmotic salinity response (GO:0042538)2.47218951
81negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.46246014
82negative regulation of calcium ion transmembrane transport (GO:1903170)2.46246014
83oxidative phosphorylation (GO:0006119)2.43081680
84branched-chain amino acid metabolic process (GO:0009081)2.42268631
85pteridine-containing compound biosynthetic process (GO:0042559)2.42182361
86regulation of feeding behavior (GO:0060259)2.41864611
87establishment of protein localization to mitochondrial membrane (GO:0090151)2.41286918
88positive regulation of protein depolymerization (GO:1901881)2.40514691
89ATP hydrolysis coupled proton transport (GO:0015991)2.40468304
90energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)2.40468304
91ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.40138862
92dendritic spine morphogenesis (GO:0060997)2.39559506
93seminiferous tubule development (GO:0072520)2.39533020
94hydrogen ion transmembrane transport (GO:1902600)2.39173325
95acrosome reaction (GO:0007340)2.38330109
96negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.38021389
97muscle filament sliding (GO:0030049)2.35685825
98actin-myosin filament sliding (GO:0033275)2.35685825
99polyol catabolic process (GO:0046174)2.35369993
100L-methionine biosynthetic process (GO:0071265)2.34960427

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.13525535
2IGF1R_20145208_ChIP-Seq_DFB_Human3.18512381
3ZNF274_21170338_ChIP-Seq_K562_Hela3.12233869
4EZH2_22144423_ChIP-Seq_EOC_Human2.96984728
5GBX2_23144817_ChIP-Seq_PC3_Human2.90858574
6GABP_17652178_ChIP-ChIP_JURKAT_Human2.84912620
7NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.72779106
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.72270907
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.61836140
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.53277982
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.47207028
12ZFP57_27257070_Chip-Seq_ESCs_Mouse2.25832901
13NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.18664384
14FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.11714955
15POU3F2_20337985_ChIP-ChIP_501MEL_Human2.07273705
16* ETS1_20019798_ChIP-Seq_JURKAT_Human1.96461630
17CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.89280041
18FUS_26573619_Chip-Seq_HEK293_Human1.88733295
19TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.88358605
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.82577870
21HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.82531556
22CTBP2_25329375_ChIP-Seq_LNCAP_Human1.81373704
23SRF_21415370_ChIP-Seq_HL-1_Mouse1.80226578
24VDR_22108803_ChIP-Seq_LS180_Human1.70733556
25CBX2_27304074_Chip-Seq_ESCs_Mouse1.70581817
26* P300_19829295_ChIP-Seq_ESCs_Human1.67301587
27CTBP1_25329375_ChIP-Seq_LNCAP_Human1.64042330
28VDR_23849224_ChIP-Seq_CD4+_Human1.59681927
29RBPJ_22232070_ChIP-Seq_NCS_Mouse1.58156097
30SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51693045
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.49147441
32SALL1_21062744_ChIP-ChIP_HESCs_Human1.46158671
33TAF15_26573619_Chip-Seq_HEK293_Human1.44744636
34TP53_22573176_ChIP-Seq_HFKS_Human1.40969865
35EWS_26573619_Chip-Seq_HEK293_Human1.38157594
36FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.37799556
37REST_21632747_ChIP-Seq_MESCs_Mouse1.37430919
38* SMAD4_21799915_ChIP-Seq_A2780_Human1.36622845
39ELK1_19687146_ChIP-ChIP_HELA_Human1.35616385
40REST_18959480_ChIP-ChIP_MESCs_Mouse1.32968350
41KLF5_20875108_ChIP-Seq_MESCs_Mouse1.31530309
42FLI1_27457419_Chip-Seq_LIVER_Mouse1.31225601
43MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30687844
44ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.29736344
45RNF2_27304074_Chip-Seq_NSC_Mouse1.28789156
46HTT_18923047_ChIP-ChIP_STHdh_Human1.21800600
47* IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20721635
48* CBP_20019798_ChIP-Seq_JUKART_Human1.20721635
49EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17511313
50OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17086107
51* GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16505370
52CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.16351671
53HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.15573618
54ER_23166858_ChIP-Seq_MCF-7_Human1.15097900
55GABP_19822575_ChIP-Seq_HepG2_Human1.14587272
56SOX2_19829295_ChIP-Seq_ESCs_Human1.13278222
57NANOG_19829295_ChIP-Seq_ESCs_Human1.13278222
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12757991
59AR_25329375_ChIP-Seq_VCAP_Human1.12516870
60PIAS1_25552417_ChIP-Seq_VCAP_Human1.12332767
61CREB1_15753290_ChIP-ChIP_HEK293T_Human1.12051473
62TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11095486
63RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.09717726
64CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.09508577
65ELF1_17652178_ChIP-ChIP_JURKAT_Human1.09437771
66* CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.09250092
67PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.08758011
68PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08636905
69BMI1_23680149_ChIP-Seq_NPCS_Mouse1.08539857
70FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.08045000
71BCAT_22108803_ChIP-Seq_LS180_Human1.07327421
72THAP11_20581084_ChIP-Seq_MESCs_Mouse1.06959288
73* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.06142880
74POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05641519
75MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05574673
76ETV2_25802403_ChIP-Seq_MESCs_Mouse1.04800243
77SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.04299994
78MYC_18940864_ChIP-ChIP_HL60_Human1.04264356
79PCGF2_27294783_Chip-Seq_ESCs_Mouse1.03258319
80SMAD3_21741376_ChIP-Seq_EPCs_Human1.01616139
81ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.00898712
82EZH2_27304074_Chip-Seq_ESCs_Mouse0.99145443
83TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96695899
84POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96695899
85GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94670363
86FOXA1_25329375_ChIP-Seq_VCAP_Human0.93591608
87FOXA1_27270436_Chip-Seq_PROSTATE_Human0.93591608
88TAL1_26923725_Chip-Seq_HPCs_Mouse0.91820257
89RUNX2_22187159_ChIP-Seq_PCA_Human0.90700660
90AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90551217
91SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.89788796
92MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.89564386
93FOXP3_21729870_ChIP-Seq_TREG_Human0.88945590
94PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.88280761
95SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.88026397
96EZH2_27294783_Chip-Seq_ESCs_Mouse0.87744110
97DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.87421411
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.87161149
99TCF4_23295773_ChIP-Seq_U87_Human0.86907167
100NR3C1_21868756_ChIP-Seq_MCF10A_Human0.86688166

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.56463857
2MP0002102_abnormal_ear_morphology3.23610836
3MP0001529_abnormal_vocalization2.92488401
4MP0002837_dystrophic_cardiac_calcinosis2.48172344
5MP0006276_abnormal_autonomic_nervous2.42145138
6MP0005423_abnormal_somatic_nervous2.38350109
7MP0006072_abnormal_retinal_apoptosis2.24960887
8MP0003011_delayed_dark_adaptation2.22759307
9MP0002822_catalepsy2.21876804
10MP0001984_abnormal_olfaction2.16973493
11MP0002638_abnormal_pupillary_reflex2.11700605
12MP0004859_abnormal_synaptic_plasticity2.08571944
13MP0004270_analgesia1.98123256
14MP0009745_abnormal_behavioral_response1.88855523
15MP0000372_irregular_coat_pigmentation1.80001245
16MP0005646_abnormal_pituitary_gland1.79652336
17MP0009046_muscle_twitch1.78864403
18MP0001968_abnormal_touch/_nociception1.77947083
19MP0002735_abnormal_chemical_nociception1.77011991
20MP0004145_abnormal_muscle_electrophysio1.75693659
21MP0002272_abnormal_nervous_system1.75212384
22MP0006036_abnormal_mitochondrial_physio1.72010363
23MP0008789_abnormal_olfactory_epithelium1.71484071
24MP0002734_abnormal_mechanical_nocicepti1.66258083
25MP0001905_abnormal_dopamine_level1.65580437
26MP0008877_abnormal_DNA_methylation1.65330666
27MP0009780_abnormal_chondrocyte_physiolo1.65246798
28MP0003787_abnormal_imprinting1.64973580
29MP0003122_maternal_imprinting1.64912064
30MP0003635_abnormal_synaptic_transmissio1.63814629
31MP0010386_abnormal_urinary_bladder1.58773956
32MP0001486_abnormal_startle_reflex1.58372234
33MP0000749_muscle_degeneration1.55686946
34MP0004142_abnormal_muscle_tone1.53594027
35MP0000751_myopathy1.52746629
36MP0002736_abnormal_nociception_after1.52269663
37MP0002572_abnormal_emotion/affect_behav1.50807853
38MP0005670_abnormal_white_adipose1.50263533
39MP0008995_early_reproductive_senescence1.46593173
40MP0005253_abnormal_eye_physiology1.45972510
41MP0005645_abnormal_hypothalamus_physiol1.44362993
42MP0005084_abnormal_gallbladder_morpholo1.42784933
43MP0005499_abnormal_olfactory_system1.40527199
44MP0005394_taste/olfaction_phenotype1.40527199
45MP0006292_abnormal_olfactory_placode1.35635440
46MP0006035_abnormal_mitochondrial_morpho1.35186894
47MP0002063_abnormal_learning/memory/cond1.35174617
48MP0005551_abnormal_eye_electrophysiolog1.34967355
49MP0002064_seizures1.34535512
50MP0003646_muscle_fatigue1.33392504
51MP0002938_white_spotting1.31903758
52MP0002557_abnormal_social/conspecific_i1.31490125
53MP0004147_increased_porphyrin_level1.30642434
54MP0001970_abnormal_pain_threshold1.26635563
55MP0002909_abnormal_adrenal_gland1.24424315
56MP0004133_heterotaxia1.21292965
57MP0003137_abnormal_impulse_conducting1.17642805
58MP0002653_abnormal_ependyma_morphology1.17035628
59MP0001299_abnormal_eye_distance/1.16962298
60MP0005386_behavior/neurological_phenoty1.15989703
61MP0004924_abnormal_behavior1.15989703
62MP0000049_abnormal_middle_ear1.13091091
63MP0002067_abnormal_sensory_capabilities1.11372764
64MP0003121_genomic_imprinting1.10712149
65MP0002163_abnormal_gland_morphology1.07852335
66MP0001501_abnormal_sleep_pattern1.06272068
67MP0001485_abnormal_pinna_reflex1.04378288
68MP0003186_abnormal_redox_activity1.04133809
69MP0004215_abnormal_myocardial_fiber1.03043186
70MP0008872_abnormal_physiological_respon1.02973509
71MP0001986_abnormal_taste_sensitivity1.02457829
72MP0002733_abnormal_thermal_nociception1.01894920
73MP0002233_abnormal_nose_morphology1.01322853
74MP0000778_abnormal_nervous_system1.00955951
75MP0000631_abnormal_neuroendocrine_gland0.99829319
76MP0002184_abnormal_innervation0.99136961
77MP0001963_abnormal_hearing_physiology0.97752453
78MP0000516_abnormal_urinary_system0.96472713
79MP0005367_renal/urinary_system_phenotyp0.96472713
80MP0000026_abnormal_inner_ear0.94838829
81MP0002876_abnormal_thyroid_physiology0.93547656
82MP0003195_calcinosis0.93531916
83MP0001440_abnormal_grooming_behavior0.92305628
84MP0002106_abnormal_muscle_physiology0.91781827
85MP0004036_abnormal_muscle_relaxation0.91118178
86MP0004085_abnormal_heartbeat0.89533531
87MP0005369_muscle_phenotype0.88646696
88MP0005620_abnormal_muscle_contractility0.88559645
89MP0002234_abnormal_pharynx_morphology0.88540025
90MP0005379_endocrine/exocrine_gland_phen0.85169491
91MP0002069_abnormal_eating/drinking_beha0.84626485
92MP0002752_abnormal_somatic_nervous0.83285178
93MP0002882_abnormal_neuron_morphology0.82053097
94MP0002277_abnormal_respiratory_mucosa0.80348630
95MP0000750_abnormal_muscle_regeneration0.77446084
96MP0005075_abnormal_melanosome_morpholog0.76904821
97MP0002090_abnormal_vision0.76738823
98MP0002066_abnormal_motor_capabilities/c0.76076568
99MP0004811_abnormal_neuron_physiology0.75331542
100MP0004885_abnormal_endolymph0.75251600

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)3.84530116
2Fetal akinesia sequence (HP:0001989)3.73014407
3Abnormal mitochondria in muscle tissue (HP:0008316)3.57942448
4Mitochondrial inheritance (HP:0001427)3.48474654
5Acute encephalopathy (HP:0006846)3.45891818
6Progressive macrocephaly (HP:0004481)3.43142297
7Hepatic necrosis (HP:0002605)3.26938045
8Hepatocellular necrosis (HP:0001404)3.25016348
9Medial flaring of the eyebrow (HP:0010747)3.21028273
10Increased CSF lactate (HP:0002490)3.11522339
11Gait imbalance (HP:0002141)3.08675959
12Rimmed vacuoles (HP:0003805)2.97026778
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.93476025
14Decreased activity of mitochondrial respiratory chain (HP:0008972)2.93476025
15Congenital primary aphakia (HP:0007707)2.92875253
16Exercise-induced muscle cramps (HP:0003710)2.84091500
17Poor suck (HP:0002033)2.83641192
18Hyperglycinemia (HP:0002154)2.79823655
19Lipid accumulation in hepatocytes (HP:0006561)2.76502198
20Increased hepatocellular lipid droplets (HP:0006565)2.74827691
21Nephrogenic diabetes insipidus (HP:0009806)2.73929386
22Methylmalonic acidemia (HP:0002912)2.69225534
23Increased intramyocellular lipid droplets (HP:0012240)2.68554357
24Pancreatic fibrosis (HP:0100732)2.64531874
25Hypoglycemic seizures (HP:0002173)2.56698245
26Abnormality of the calf musculature (HP:0001430)2.51886665
27Myokymia (HP:0002411)2.50718111
28Muscle fiber inclusion bodies (HP:0100299)2.50237799
29Lactic acidosis (HP:0003128)2.48566009
30Limb-girdle muscle atrophy (HP:0003797)2.44892890
31Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.40878715
32Increased muscle lipid content (HP:0009058)2.40552388
33Polyphagia (HP:0002591)2.40345814
34Nemaline bodies (HP:0003798)2.40196262
35Tubulointerstitial nephritis (HP:0001970)2.37023691
36Pancreatic cysts (HP:0001737)2.36535061
37Muscle hypertrophy of the lower extremities (HP:0008968)2.34851631
38Exercise intolerance (HP:0003546)2.32571144
39Type 2 muscle fiber atrophy (HP:0003554)2.31177619
40True hermaphroditism (HP:0010459)2.30976034
41Molar tooth sign on MRI (HP:0002419)2.29278559
42Abnormality of midbrain morphology (HP:0002418)2.29278559
43Failure to thrive in infancy (HP:0001531)2.28729216
44Focal motor seizures (HP:0011153)2.28583500
45Genital tract atresia (HP:0001827)2.28195968
46Renal Fanconi syndrome (HP:0001994)2.27880027
47Respiratory failure (HP:0002878)2.27158457
48Abnormality of the labia minora (HP:0012880)2.22809348
49Limb dystonia (HP:0002451)2.22251981
50Cerebral edema (HP:0002181)2.21927339
51Muscle fiber splitting (HP:0003555)2.19799257
52Intestinal atresia (HP:0011100)2.18419202
53Vaginal atresia (HP:0000148)2.17190160
54Calf muscle hypertrophy (HP:0008981)2.17158825
55Methylmalonic aciduria (HP:0012120)2.15635996
56Aplasia/Hypoplasia involving the musculature (HP:0001460)2.14736156
57Hip dysplasia (HP:0001385)2.12177143
58Broad-based gait (HP:0002136)2.09254894
59Nephronophthisis (HP:0000090)2.07142027
60Myoglobinuria (HP:0002913)2.04348584
61Exercise-induced myalgia (HP:0003738)2.03312900
62Increased serum lactate (HP:0002151)2.03201624
63Aplasia of the musculature (HP:0100854)2.00372240
643-Methylglutaconic aciduria (HP:0003535)1.99655956
65Retinal dysplasia (HP:0007973)1.99376672
66Hypothermia (HP:0002045)1.99129182
67Optic disc pallor (HP:0000543)1.95593805
68Hyperinsulinemic hypoglycemia (HP:0000825)1.93932599
69Delayed CNS myelination (HP:0002188)1.90603321
70Postaxial hand polydactyly (HP:0001162)1.90442366
71Median cleft lip (HP:0000161)1.89776483
72Abnormality of glycolysis (HP:0004366)1.89407991
73Hypoglycemic coma (HP:0001325)1.88214593
74Muscle fiber atrophy (HP:0100295)1.87911740
75Hemiparesis (HP:0001269)1.87595966
76Aplasia/hypoplasia of the uterus (HP:0008684)1.87131157
77Short tibia (HP:0005736)1.86078384
78Myopathic facies (HP:0002058)1.85572005
79Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.83347009
80Abnormal protein N-linked glycosylation (HP:0012347)1.83347009
81Abnormal protein glycosylation (HP:0012346)1.83347009
82Abnormal glycosylation (HP:0012345)1.83347009
83Rhabdomyolysis (HP:0003201)1.82876415
84Abnormality of dicarboxylic acid metabolism (HP:0010995)1.82488059
85Dicarboxylic aciduria (HP:0003215)1.82488059
86Increased serum pyruvate (HP:0003542)1.79162581
87Type II lissencephaly (HP:0007260)1.77338315
88Urinary urgency (HP:0000012)1.77330218
89Specific learning disability (HP:0001328)1.76468905
90Abnormality of serine family amino acid metabolism (HP:0010894)1.76388041
91Abnormality of glycine metabolism (HP:0010895)1.76388041
92Ketoacidosis (HP:0001993)1.75512938
93Abnormality of the metopic suture (HP:0005556)1.75017391
94Abnormality of urine glucose concentration (HP:0011016)1.73743422
95Glycosuria (HP:0003076)1.73743422
96Sleep apnea (HP:0010535)1.72420331
97Left ventricular hypertrophy (HP:0001712)1.71485261
98CNS demyelination (HP:0007305)1.71422429
99Absent speech (HP:0001344)1.71101733
100Oligomenorrhea (HP:0000876)1.70448218

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K23.89914648
2WNK32.88708510
3STK162.88304711
4PINK12.87350011
5OBSCN2.50721177
6MARK12.44651114
7BCKDK2.31816741
8MAP2K72.30884249
9CDK192.30642617
10MAP3K42.20032078
11TESK12.05467662
12TRIM281.98607385
13PRKD31.96753397
14PHKG21.89916607
15PHKG11.89916607
16MAPK131.89824487
17CASK1.83833878
18LIMK11.80749029
19TIE11.77081517
20FRK1.69616426
21GRK11.65624143
22INSRR1.60721878
23NME21.55361431
24NTRK31.53082743
25CSNK1G31.53066264
26DYRK21.52701552
27TESK21.50475168
28CSNK1G21.49852895
29RPS6KA41.49725320
30BCR1.45938461
31BMPR1B1.44562732
32CCNB11.42940811
33ADRBK21.42188219
34SRPK11.40148847
35ERBB31.35707299
36CSNK1G11.31858173
37EPHA41.31008568
38VRK21.14896904
39ZAK1.14569966
40CSNK1A1L1.13926028
41MAP2K41.06517759
42NUAK10.96559960
43PIM20.90463509
44PLK40.90070382
45RPS6KA50.88955640
46PLK20.88401518
47NME10.87769302
48MINK10.87173847
49NTRK20.85389912
50PRKCE0.84820726
51ARAF0.83344314
52VRK10.83060868
53PAK60.82900679
54LMTK20.80058790
55MUSK0.78362020
56PRKCG0.77207956
57FLT30.74077784
58CAMK2G0.72440515
59TLK10.71766203
60FGFR20.71167042
61DAPK20.70507508
62UHMK10.69029686
63CAMK10.67556264
64PAK30.66224994
65CDK30.63965097
66CAMK2A0.61458314
67DAPK10.59362662
68PASK0.58494250
69PRKD20.58453684
70DYRK30.57551749
71MAP3K120.56977548
72TNK20.53782198
73OXSR10.50434159
74GRK50.50167148
75CDK50.50080377
76PKN10.49079841
77NEK10.48991502
78PRKACA0.47176949
79MAP3K50.46675962
80DYRK1A0.46528876
81CAMKK20.46153569
82MAP2K60.45909479
83CAMK2B0.45529499
84CAMK2D0.44809752
85ABL20.44230574
86CDK140.41661797
87PDK20.41393764
88STK38L0.40064723
89MYLK0.38968413
90FER0.37992218
91PRKG10.37663918
92SIK30.36889251
93PRKAA10.36354805
94EPHA30.36133823
95CSNK1A10.35970698
96SGK4940.34540612
97SGK2230.34540612
98PKN20.33399975
99MAP3K60.32678323
100SIK20.32136182

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.53861805
2Parkinsons disease_Homo sapiens_hsa050123.02299398
3Propanoate metabolism_Homo sapiens_hsa006402.67891976
4Protein export_Homo sapiens_hsa030602.55969530
5Butanoate metabolism_Homo sapiens_hsa006502.48925304
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.43522728
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.32029294
8Cardiac muscle contraction_Homo sapiens_hsa042602.31626283
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.19121961
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.18902291
11Fatty acid elongation_Homo sapiens_hsa000622.14770754
12Proteasome_Homo sapiens_hsa030502.12207693
13Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.97945553
14Huntingtons disease_Homo sapiens_hsa050161.91452661
15Alzheimers disease_Homo sapiens_hsa050101.91198551
16Regulation of autophagy_Homo sapiens_hsa041401.83467382
17Peroxisome_Homo sapiens_hsa041461.80929997
18Nicotine addiction_Homo sapiens_hsa050331.79713770
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.68107653
20RNA polymerase_Homo sapiens_hsa030201.66378690
21Folate biosynthesis_Homo sapiens_hsa007901.57915653
22Synaptic vesicle cycle_Homo sapiens_hsa047211.55013442
23Collecting duct acid secretion_Homo sapiens_hsa049661.54910206
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.45656671
25Circadian rhythm_Homo sapiens_hsa047101.44555725
26Steroid biosynthesis_Homo sapiens_hsa001001.44025811
27Basal transcription factors_Homo sapiens_hsa030221.36151093
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.34587736
29GABAergic synapse_Homo sapiens_hsa047271.34427014
30Ribosome_Homo sapiens_hsa030101.33681287
31Pyruvate metabolism_Homo sapiens_hsa006201.31269154
32Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.28239829
33Maturity onset diabetes of the young_Homo sapiens_hsa049501.25920677
34Phototransduction_Homo sapiens_hsa047441.21458012
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.19671419
36beta-Alanine metabolism_Homo sapiens_hsa004101.15491335
37Sulfur relay system_Homo sapiens_hsa041221.15238685
38Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.14744418
39Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.14597933
40Primary bile acid biosynthesis_Homo sapiens_hsa001201.10184364
41Carbon metabolism_Homo sapiens_hsa012001.08864076
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.06512710
43Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.06375709
44Fatty acid metabolism_Homo sapiens_hsa012121.04529530
45Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.03833939
46Tryptophan metabolism_Homo sapiens_hsa003801.03206694
47Insulin secretion_Homo sapiens_hsa049110.97488991
48Purine metabolism_Homo sapiens_hsa002300.94905328
49Metabolic pathways_Homo sapiens_hsa011000.90887975
50Base excision repair_Homo sapiens_hsa034100.89498423
51Morphine addiction_Homo sapiens_hsa050320.88623580
52RNA degradation_Homo sapiens_hsa030180.87695945
53Dopaminergic synapse_Homo sapiens_hsa047280.87538252
54Fatty acid degradation_Homo sapiens_hsa000710.86025565
55Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.84945020
56Circadian entrainment_Homo sapiens_hsa047130.84205096
57Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.83964168
58Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.81583761
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.78882301
60Glutathione metabolism_Homo sapiens_hsa004800.76923183
61Olfactory transduction_Homo sapiens_hsa047400.75622151
62Taste transduction_Homo sapiens_hsa047420.73244282
63Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.73064761
64Vibrio cholerae infection_Homo sapiens_hsa051100.72634827
65Arginine and proline metabolism_Homo sapiens_hsa003300.72238869
66Vitamin B6 metabolism_Homo sapiens_hsa007500.71477868
67Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.67576089
68Pyrimidine metabolism_Homo sapiens_hsa002400.65838395
69Salivary secretion_Homo sapiens_hsa049700.61019115
70Glutamatergic synapse_Homo sapiens_hsa047240.59962469
71Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59834584
72Amphetamine addiction_Homo sapiens_hsa050310.59353171
73Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.59111170
74Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58973660
75Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.56181575
76Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.53956615
77Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.52543617
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.52044578
79Chemical carcinogenesis_Homo sapiens_hsa052040.51245896
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.49077490
81Dilated cardiomyopathy_Homo sapiens_hsa054140.47908540
82Nitrogen metabolism_Homo sapiens_hsa009100.47894207
83Retinol metabolism_Homo sapiens_hsa008300.47862002
84SNARE interactions in vesicular transport_Homo sapiens_hsa041300.45795430
85Biosynthesis of amino acids_Homo sapiens_hsa012300.44601788
86Fanconi anemia pathway_Homo sapiens_hsa034600.43499386
87Oxytocin signaling pathway_Homo sapiens_hsa049210.42516744
88Nucleotide excision repair_Homo sapiens_hsa034200.42225339
89Cocaine addiction_Homo sapiens_hsa050300.41962294
90Renin secretion_Homo sapiens_hsa049240.41555236
91alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.38233603
92Calcium signaling pathway_Homo sapiens_hsa040200.37510998
93Serotonergic synapse_Homo sapiens_hsa047260.36796796
94Glucagon signaling pathway_Homo sapiens_hsa049220.35609699
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34730980
96Steroid hormone biosynthesis_Homo sapiens_hsa001400.34078497
97Hedgehog signaling pathway_Homo sapiens_hsa043400.33754962
98Linoleic acid metabolism_Homo sapiens_hsa005910.33563043
99Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32694036
100Oocyte meiosis_Homo sapiens_hsa041140.31994689

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