ZNF343

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1seminiferous tubule development (GO:0072520)4.96502288
2hindbrain development (GO:0030902)4.80413581
3regulation of hippo signaling (GO:0035330)4.54452803
4response to pheromone (GO:0019236)4.41176816
5replication fork processing (GO:0031297)4.12583049
6monoubiquitinated protein deubiquitination (GO:0035520)4.04842718
7transcription elongation from RNA polymerase I promoter (GO:0006362)3.99780462
8snRNA transcription (GO:0009301)3.97331845
9regulation of RNA export from nucleus (GO:0046831)3.88411696
10single strand break repair (GO:0000012)3.74841868
11protein K6-linked ubiquitination (GO:0085020)3.73690278
12termination of RNA polymerase I transcription (GO:0006363)3.71310297
13negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.57401817
14negative regulation of translation, ncRNA-mediated (GO:0040033)3.57401817
15regulation of translation, ncRNA-mediated (GO:0045974)3.57401817
16cilium or flagellum-dependent cell motility (GO:0001539)3.44901327
17uterus development (GO:0060065)3.40294776
18nonmotile primary cilium assembly (GO:0035058)3.36126964
19ribonucleoprotein complex disassembly (GO:0032988)3.32553623
20cornea development in camera-type eye (GO:0061303)3.31098551
21transcription initiation from RNA polymerase I promoter (GO:0006361)3.31023355
22protein localization to synapse (GO:0035418)3.24892570
23behavioral response to nicotine (GO:0035095)3.24305893
24L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.18985682
25cellular response to ATP (GO:0071318)3.15323362
26regulation of bile acid biosynthetic process (GO:0070857)3.10612616
27regulation of nucleobase-containing compound transport (GO:0032239)3.09122470
28spinal cord development (GO:0021510)3.06802044
29neural tube formation (GO:0001841)3.05163326
30axonemal dynein complex assembly (GO:0070286)3.03701244
31positive regulation of mitochondrial fission (GO:0090141)3.03649111
32nuclear pore complex assembly (GO:0051292)3.00200684
33intestinal cholesterol absorption (GO:0030299)2.99914659
34regulation of hexokinase activity (GO:1903299)2.96395032
35regulation of glucokinase activity (GO:0033131)2.96395032
36translesion synthesis (GO:0019985)2.95444015
37positive regulation of dendritic spine morphogenesis (GO:0061003)2.93081666
38maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.92479797
39presynaptic membrane assembly (GO:0097105)2.88703433
40somatic hypermutation of immunoglobulin genes (GO:0016446)2.86941060
41somatic diversification of immune receptors via somatic mutation (GO:0002566)2.86941060
42sympathetic nervous system development (GO:0048485)2.86587840
43methionine biosynthetic process (GO:0009086)2.84522019
44chemosensory behavior (GO:0007635)2.83844001
45nuclear pore organization (GO:0006999)2.83716589
46organelle disassembly (GO:1903008)2.80138175
47neuronal action potential propagation (GO:0019227)2.79122725
48DNA methylation involved in gamete generation (GO:0043046)2.75945888
49DNA double-strand break processing (GO:0000729)2.75331041
50multicellular organism reproduction (GO:0032504)2.75042668
51ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.73860776
52protein import into peroxisome matrix (GO:0016558)2.72723003
53L-methionine salvage (GO:0071267)2.70373281
54L-methionine biosynthetic process (GO:0071265)2.70373281
55amino acid salvage (GO:0043102)2.70373281
56mitochondrial RNA metabolic process (GO:0000959)2.69573931
57regulation of DNA endoreduplication (GO:0032875)2.68368061
58rRNA transcription (GO:0009303)2.68269927
59piRNA metabolic process (GO:0034587)2.68084521
60viral mRNA export from host cell nucleus (GO:0046784)2.66484018
61postreplication repair (GO:0006301)2.64595661
62neurotransmitter-gated ion channel clustering (GO:0072578)2.58110979
63regulation of protein polyubiquitination (GO:1902914)2.54235691
64meiotic chromosome segregation (GO:0045132)2.51871483
65indolalkylamine catabolic process (GO:0046218)2.51617227
66tryptophan catabolic process (GO:0006569)2.51617227
67indole-containing compound catabolic process (GO:0042436)2.51617227
68gene silencing by RNA (GO:0031047)2.51425428
69heparin biosynthetic process (GO:0030210)2.50491609
70heparin metabolic process (GO:0030202)2.50491609
71substrate-independent telencephalic tangential migration (GO:0021826)2.49054545
72substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.49054545
73tongue development (GO:0043586)2.48837984
74regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033392.48110513
75C4-dicarboxylate transport (GO:0015740)2.47797290
76very-low-density lipoprotein particle assembly (GO:0034379)2.47598155
77startle response (GO:0001964)2.44659583
78interkinetic nuclear migration (GO:0022027)2.44080831
79RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.40354512
80positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.40261859
81positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.40261859
82positive regulation of mitotic sister chromatid separation (GO:1901970)2.40261859
83microtubule anchoring (GO:0034453)2.40134656
84primary amino compound metabolic process (GO:1901160)2.38898204
85aspartate family amino acid biosynthetic process (GO:0009067)2.38746323
86protein polyglutamylation (GO:0018095)2.37686565
87limb bud formation (GO:0060174)2.37193983
88presynaptic membrane organization (GO:0097090)2.36506789
89transcription from RNA polymerase I promoter (GO:0006360)2.34912492
90methionine metabolic process (GO:0006555)2.34881904
91reciprocal DNA recombination (GO:0035825)2.34811029
92reciprocal meiotic recombination (GO:0007131)2.34811029
93peripheral nervous system neuron development (GO:0048935)2.34228135
94negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.32917225
95zinc ion homeostasis (GO:0055069)2.31883139
96glycerophospholipid catabolic process (GO:0046475)2.30487028
97regulation of centriole replication (GO:0046599)2.30473253
98regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.30470204
99DNA methylation (GO:0006306)2.24890014
100DNA alkylation (GO:0006305)2.24890014

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse4.40147917
2ZNF274_21170338_ChIP-Seq_K562_Hela3.84619522
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.42884732
4SALL1_21062744_ChIP-ChIP_HESCs_Human3.30443754
5EZH2_22144423_ChIP-Seq_EOC_Human3.12737898
6NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.94140727
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.91128184
8* GABP_17652178_ChIP-ChIP_JURKAT_Human2.76706508
9E2F7_22180533_ChIP-Seq_HELA_Human2.68936049
10NOTCH1_21737748_ChIP-Seq_TLL_Human2.64045962
11* EST1_17652178_ChIP-ChIP_JURKAT_Human2.57338237
12* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.50479512
13IGF1R_20145208_ChIP-Seq_DFB_Human2.48321913
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.47379714
15GBX2_23144817_ChIP-Seq_PC3_Human2.40360042
16KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.40311452
17* ETS1_20019798_ChIP-Seq_JURKAT_Human2.31102178
18PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.29886070
19IRF1_19129219_ChIP-ChIP_H3396_Human2.25780991
20JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.20250166
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.17666993
22RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.13797334
23ELK1_19687146_ChIP-ChIP_HELA_Human2.06119287
24GABP_19822575_ChIP-Seq_HepG2_Human2.05563592
25KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.03898680
26EWS_26573619_Chip-Seq_HEK293_Human2.02576136
27CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.94276248
28POU3F2_20337985_ChIP-ChIP_501MEL_Human1.87964266
29YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.82223422
30TAF15_26573619_Chip-Seq_HEK293_Human1.77947229
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.75766420
32E2F4_17652178_ChIP-ChIP_JURKAT_Human1.74678322
33SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.74612292
34TP53_16413492_ChIP-PET_HCT116_Human1.71956698
35FUS_26573619_Chip-Seq_HEK293_Human1.71587676
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.70333993
37TP63_19390658_ChIP-ChIP_HaCaT_Human1.68314806
38VDR_23849224_ChIP-Seq_CD4+_Human1.64291785
39VDR_22108803_ChIP-Seq_LS180_Human1.59264980
40SRF_21415370_ChIP-Seq_HL-1_Mouse1.58061937
41* MYC_18940864_ChIP-ChIP_HL60_Human1.55268706
42PADI4_21655091_ChIP-ChIP_MCF-7_Human1.55046619
43KDM5A_27292631_Chip-Seq_BREAST_Human1.53806424
44CREB1_15753290_ChIP-ChIP_HEK293T_Human1.51658250
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.49687350
46STAT3_23295773_ChIP-Seq_U87_Human1.47108019
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.46420233
48CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45538570
49MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.44041406
50MEF2A_21415370_ChIP-Seq_HL-1_Mouse1.43760893
51HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.39575248
52TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.38216954
53FOXP3_21729870_ChIP-Seq_TREG_Human1.35567765
54CIITA_25753668_ChIP-Seq_RAJI_Human1.33906044
55DCP1A_22483619_ChIP-Seq_HELA_Human1.32734829
56FOXA2_19822575_ChIP-Seq_HepG2_Human1.26571851
57PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.25026746
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25003141
59AR_21572438_ChIP-Seq_LNCaP_Human1.21789278
60YY1_21170310_ChIP-Seq_MESCs_Mouse1.21731328
61EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.21624493
62FLI1_27457419_Chip-Seq_LIVER_Mouse1.18517531
63CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.18190422
64PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.17974646
65TCF4_23295773_ChIP-Seq_U87_Human1.15333055
66CBX2_27304074_Chip-Seq_ESCs_Mouse1.13833539
67SMAD4_21799915_ChIP-Seq_A2780_Human1.12686140
68AR_25329375_ChIP-Seq_VCAP_Human1.12625602
69UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11803636
70P300_19829295_ChIP-Seq_ESCs_Human1.11476949
71AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.10287803
72KLF5_20875108_ChIP-Seq_MESCs_Mouse1.05448028
73ER_23166858_ChIP-Seq_MCF-7_Human1.05391456
74THAP11_20581084_ChIP-Seq_MESCs_Mouse1.05040580
75* HNF4A_19822575_ChIP-Seq_HepG2_Human1.00088302
76PKCTHETA_26484144_Chip-Seq_BREAST_Human0.99568353
77FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.97366437
78MYCN_18555785_ChIP-Seq_MESCs_Mouse0.97062467
79PCGF2_27294783_Chip-Seq_ESCs_Mouse0.96919173
80CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96644058
81MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95741164
82ELF1_17652178_ChIP-ChIP_JURKAT_Human0.95477852
83PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.95220245
84JUN_21703547_ChIP-Seq_K562_Human0.94294682
85TTF2_22483619_ChIP-Seq_HELA_Human0.93520588
86IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.93381226
87CBP_20019798_ChIP-Seq_JUKART_Human0.93381226
88HOXB7_26014856_ChIP-Seq_BT474_Human0.92825404
89E2F1_21310950_ChIP-Seq_MCF-7_Human0.92561882
90CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.91284823
91SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.91044592
92POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.89394339
93E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.87614357
94CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.86373726
95TP53_22573176_ChIP-Seq_HFKS_Human0.82950245
96CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.82937187
97SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.81672159
98RNF2_27304074_Chip-Seq_NSC_Mouse0.81106008
99GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80664888
100TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.78672149

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001986_abnormal_taste_sensitivity4.27450311
2MP0003123_paternal_imprinting3.52850622
3MP0003121_genomic_imprinting2.97912326
4MP0005187_abnormal_penis_morphology2.87376257
5MP0003122_maternal_imprinting2.80469004
6MP0003315_abnormal_perineum_morphology2.68717361
7MP0003646_muscle_fatigue2.51065627
8MP0000427_abnormal_hair_cycle2.16750068
9MP0005451_abnormal_body_composition2.15382532
10MP0005408_hypopigmentation2.11205585
11MP0002160_abnormal_reproductive_system2.10825657
12MP0008058_abnormal_DNA_repair1.99693225
13MP0001661_extended_life_span1.98971349
14MP0004145_abnormal_muscle_electrophysio1.97852451
15MP0003890_abnormal_embryonic-extraembry1.93894078
16MP0003868_abnormal_feces_composition1.89371064
17MP0008789_abnormal_olfactory_epithelium1.82156224
18MP0003195_calcinosis1.80511592
19MP0009697_abnormal_copulation1.76275998
20MP0005645_abnormal_hypothalamus_physiol1.74906841
21MP0005389_reproductive_system_phenotype1.73919708
22MP0003111_abnormal_nucleus_morphology1.71650961
23MP0001984_abnormal_olfaction1.67410046
24MP0008775_abnormal_heart_ventricle1.63119222
25MP0008057_abnormal_DNA_replication1.60242387
26MP0002837_dystrophic_cardiac_calcinosis1.54931176
27MP0003787_abnormal_imprinting1.52392248
28MP0006035_abnormal_mitochondrial_morpho1.49051476
29MP0002735_abnormal_chemical_nociception1.46546185
30MP0000372_irregular_coat_pigmentation1.46025300
31MP0001666_abnormal_nutrient_absorption1.44736469
32MP0008995_early_reproductive_senescence1.40058314
33MP0005551_abnormal_eye_electrophysiolog1.35831455
34MP0000647_abnormal_sebaceous_gland1.35511614
35MP0008961_abnormal_basal_metabolism1.35294342
36MP0002089_abnormal_postnatal_growth/wei1.35060071
37MP0001968_abnormal_touch/_nociception1.34759565
38MP0005394_taste/olfaction_phenotype1.31041488
39MP0005499_abnormal_olfactory_system1.31041488
40MP0004233_abnormal_muscle_weight1.30444347
41MP0002938_white_spotting1.29942790
42MP0002102_abnormal_ear_morphology1.28752271
43MP0001919_abnormal_reproductive_system1.28028368
44MP0005220_abnormal_exocrine_pancreas1.22333628
45MP0010094_abnormal_chromosome_stability1.21556667
46MP0000569_abnormal_digit_pigmentation1.21523352
47MP0004133_heterotaxia1.19283641
48MP0004924_abnormal_behavior1.19255072
49MP0005386_behavior/neurological_phenoty1.19255072
50MP0002233_abnormal_nose_morphology1.13293390
51MP0002876_abnormal_thyroid_physiology1.12400338
52MP0003786_premature_aging1.09850145
53MP0008875_abnormal_xenobiotic_pharmacok1.09814894
54MP0010329_abnormal_lipoprotein_level1.08775119
55MP0003119_abnormal_digestive_system1.06918473
56MP0002210_abnormal_sex_determination1.06654137
57MP0001270_distended_abdomen1.05172856
58MP0002557_abnormal_social/conspecific_i1.03899015
59MP0001324_abnormal_eye_pigmentation1.02158675
60MP0004134_abnormal_chest_morphology1.01278323
61MP0003950_abnormal_plasma_membrane1.01244142
62MP0002184_abnormal_innervation0.99833691
63MP0001929_abnormal_gametogenesis0.99035761
64MP0000358_abnormal_cell_content/0.97444658
65MP0005195_abnormal_posterior_eye0.96385013
66MP0003755_abnormal_palate_morphology0.96285067
67MP0006292_abnormal_olfactory_placode0.95793301
68MP0006072_abnormal_retinal_apoptosis0.94962946
69MP0005647_abnormal_sex_gland0.94950629
70MP0001944_abnormal_pancreas_morphology0.94544473
71MP0003385_abnormal_body_wall0.94516260
72MP0000003_abnormal_adipose_tissue0.93400085
73MP0003943_abnormal_hepatobiliary_system0.92510754
74MP0002928_abnormal_bile_duct0.92505418
75MP0002638_abnormal_pupillary_reflex0.90379299
76MP0003698_abnormal_male_reproductive0.90261732
77MP0003693_abnormal_embryo_hatching0.89419288
78MP0003937_abnormal_limbs/digits/tail_de0.86504739
79MP0009250_abnormal_appendicular_skeleto0.86408493
80MP0000639_abnormal_adrenal_gland0.86271258
81MP0004185_abnormal_adipocyte_glucose0.86196477
82MP0001299_abnormal_eye_distance/0.85339833
83MP0009046_muscle_twitch0.84189790
84MP0000538_abnormal_urinary_bladder0.81277872
85MP0000778_abnormal_nervous_system0.80686436
86MP0003252_abnormal_bile_duct0.80154940
87MP0002234_abnormal_pharynx_morphology0.78390806
88MP0001145_abnormal_male_reproductive0.76078443
89MP0005334_abnormal_fat_pad0.74549101
90MP0000653_abnormal_sex_gland0.74543575
91MP0004043_abnormal_pH_regulation0.73560298
92MP0002282_abnormal_trachea_morphology0.73339595
93MP0003221_abnormal_cardiomyocyte_apopto0.73328445
94MP0005253_abnormal_eye_physiology0.72797178
95MP0002752_abnormal_somatic_nervous0.72704909
96MP0006054_spinal_hemorrhage0.72299072
97MP0002751_abnormal_autonomic_nervous0.72134252
98MP0004742_abnormal_vestibular_system0.72078867
99MP0002095_abnormal_skin_pigmentation0.71259848
100MP0003942_abnormal_urinary_system0.71120275

Predicted human phenotypes

RankGene SetZ-score
1Cutaneous melanoma (HP:0012056)4.60984498
2Hyperventilation (HP:0002883)4.11780332
3Protruding tongue (HP:0010808)3.88827665
4Renal cortical cysts (HP:0000803)3.72444961
5Exotropia (HP:0000577)3.71291535
6Broad-based gait (HP:0002136)3.32049102
7Drooling (HP:0002307)3.21114375
8Abnormality of midbrain morphology (HP:0002418)3.04562881
9Molar tooth sign on MRI (HP:0002419)3.04562881
10Enlarged penis (HP:0000040)3.02838688
11Macroorchidism (HP:0000053)3.02476125
12Medial flaring of the eyebrow (HP:0010747)2.98266996
13Nephronophthisis (HP:0000090)2.91540854
14Excessive salivation (HP:0003781)2.83957423
15Congenital primary aphakia (HP:0007707)2.75659815
16Chronic hepatic failure (HP:0100626)2.74960514
17Chronic otitis media (HP:0000389)2.70319696
18Poor coordination (HP:0002370)2.67306466
19Lissencephaly (HP:0001339)2.67024664
20Nephrogenic diabetes insipidus (HP:0009806)2.66574035
21Abnormality of the renal cortex (HP:0011035)2.62822620
22Gait imbalance (HP:0002141)2.60453668
23Fair hair (HP:0002286)2.60119193
24Infantile muscular hypotonia (HP:0008947)2.59910255
25Broad alveolar ridges (HP:0000187)2.54542168
26Hypoplasia of the capital femoral epiphysis (HP:0003090)2.52465838
27Chronic sinusitis (HP:0011109)2.50142038
28Abnormality of the renal medulla (HP:0100957)2.43325221
29Poikiloderma (HP:0001029)2.42189709
30Hypothermia (HP:0002045)2.38290925
31True hermaphroditism (HP:0010459)2.38260793
32Squamous cell carcinoma (HP:0002860)2.37256814
33Gonadotropin excess (HP:0000837)2.36499848
34Clumsiness (HP:0002312)2.34891613
35Abnormal respiratory motile cilium morphology (HP:0005938)2.33238206
36Abnormal respiratory epithelium morphology (HP:0012253)2.33238206
37Abnormality of DNA repair (HP:0003254)2.32596756
38Termporal pattern (HP:0011008)2.31888643
39Insidious onset (HP:0003587)2.31888643
40Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.29330273
41Neoplasm of the adrenal cortex (HP:0100641)2.29319724
42Pancreatic fibrosis (HP:0100732)2.28371533
43Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.24819335
44Abnormality of alanine metabolism (HP:0010916)2.24819335
45Hyperalaninemia (HP:0003348)2.24819335
46Tented upper lip vermilion (HP:0010804)2.24703447
47Chromsome breakage (HP:0040012)2.24701061
48Chromosomal breakage induced by crosslinking agents (HP:0003221)2.23406328
49Absent speech (HP:0001344)2.17074540
50Upper limb muscle weakness (HP:0003484)2.16275708
51Progressive inability to walk (HP:0002505)2.12403508
52Pancreatic cysts (HP:0001737)2.12311767
53Adrenal hypoplasia (HP:0000835)2.10311855
54Small epiphyses (HP:0010585)2.09781790
55Hypobetalipoproteinemia (HP:0003563)2.08405887
56Decreased testicular size (HP:0008734)2.07922935
57Abnormality of the astrocytes (HP:0100707)2.06240457
58Astrocytoma (HP:0009592)2.06240457
59Deep venous thrombosis (HP:0002625)2.05058999
60Enlarged kidneys (HP:0000105)2.01113015
61Patellar aplasia (HP:0006443)1.98488936
62Volvulus (HP:0002580)1.98127374
63Ectopic kidney (HP:0000086)1.95495967
64Status epilepticus (HP:0002133)1.92049241
65Tapered finger (HP:0001182)1.91094587
66Neonatal onset (HP:0003623)1.90834482
67Pachygyria (HP:0001302)1.90487152
68Atonic seizures (HP:0010819)1.90240902
69Osteomalacia (HP:0002749)1.85606315
70Entropion (HP:0000621)1.85446340
71Abnormality of the wing of the ilium (HP:0011867)1.83725586
72Prolonged partial thromboplastin time (HP:0003645)1.83553505
73Abnormal pupillary function (HP:0007686)1.82721592
74Postaxial foot polydactyly (HP:0001830)1.81706938
75Irregular epiphyses (HP:0010582)1.81499334
76Aplasia/Hypoplasia of the fovea (HP:0008060)1.80373594
77Hypoplasia of the fovea (HP:0007750)1.80373594
78Generalized hypopigmentation of hair (HP:0011358)1.79636470
79Thyroiditis (HP:0100646)1.78861734
80Ependymoma (HP:0002888)1.77591931
81Short foot (HP:0001773)1.76876514
82Vaginal atresia (HP:0000148)1.76650164
83Brushfield spots (HP:0001088)1.76628756
84Aplasia/Hypoplasia of the patella (HP:0006498)1.76601732
85Attenuation of retinal blood vessels (HP:0007843)1.76573740
86Genital tract atresia (HP:0001827)1.74759309
87Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.74754871
88Absent epiphyses (HP:0010577)1.74754871
89Oligodactyly (hands) (HP:0001180)1.72445548
90High anterior hairline (HP:0009890)1.69651310
91Aplasia/Hypoplasia of the tongue (HP:0010295)1.69216376
92Gastroesophageal reflux (HP:0002020)1.66738604
93Aplastic anemia (HP:0001915)1.66546245
94Heterotopia (HP:0002282)1.66093028
95Hepatoblastoma (HP:0002884)1.65289813
96Febrile seizures (HP:0002373)1.65204703
97Hypophosphatemic rickets (HP:0004912)1.64164419
98Metaphyseal irregularity (HP:0003025)1.64151765
99Facial hemangioma (HP:0000329)1.63856558
100Increased serum pyruvate (HP:0003542)1.62422951

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK5.88760102
2FRK4.81790528
3WNK43.85341358
4INSRR3.03574717
5STK392.99314882
6ICK2.63399089
7PINK12.56984029
8CAMK1D2.40042966
9MAP2K72.31408207
10MAP3K42.25769938
11AKT31.91672255
12MUSK1.76013476
13SIK21.75201052
14CAMK1G1.68477002
15CDK121.66975333
16PLK41.63024264
17DYRK31.55465662
18FGFR31.50318746
19BRSK21.47710782
20BRD41.44208616
21FGFR21.39886640
22MET1.30310612
23ZAK1.23103413
24CAMKK21.20438084
25WNK31.18904609
26NEK21.13681962
27CDK81.08329045
28CDC71.05053143
29LATS11.04521353
30TLK11.04038716
31ATR1.02150774
32BMPR1B0.99094282
33EIF2AK30.97939634
34CAMK40.95718409
35MST1R0.92503793
36PHKG20.90690106
37PHKG10.90690106
38PRKAA20.87602793
39FGFR40.84774077
40PLK10.82943578
41ADRBK20.82687218
42CSNK1A1L0.80246683
43BCR0.79263984
44OXSR10.79079347
45ATM0.78561307
46EPHB10.77712929
47PRKAA10.77041103
48PIK3CA0.73664883
49EEF2K0.72135970
50WNK10.69097562
51TYRO30.67723779
52NEK10.67426281
53SGK30.67147265
54MARK10.66373695
55RIPK10.65431051
56SGK20.64634124
57PLK20.64265671
58CHEK10.64207887
59CHUK0.61432345
60WEE10.61291080
61ERBB30.60409028
62MST40.60082087
63CCNB10.59987469
64PRKCE0.58662534
65CSNK1G10.57798101
66TGFBR20.57758477
67TRIM280.57106550
68MAP2K40.56785534
69PAK30.56675927
70PDK20.56539126
71MAP3K50.56166629
72NTRK20.54849245
73NEK90.54185250
74RPS6KA40.54092548
75CHEK20.53671394
76CSNK1G30.51397913
77NTRK30.50652168
78MAP3K60.50096711
79MAP3K140.49674798
80VRK10.47722772
81SGK4940.47651202
82SGK2230.47651202
83MAPK130.47493480
84CDK70.47306515
85MAP3K70.47190260
86MAPK110.46105997
87PLK30.46030970
88OBSCN0.45345559
89STK38L0.44430106
90SRPK10.43978447
91CDK10.43112119
92MELK0.42750950
93EPHB20.41307905
94PRKD20.41004545
95BRSK10.40610018
96IRAK30.40170463
97MARK20.40021713
98CDK20.39307178
99MAP3K130.38172169
100LIMK10.37054092

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal transcription factors_Homo sapiens_hsa030223.24307384
2Non-homologous end-joining_Homo sapiens_hsa034503.08159313
3RNA polymerase_Homo sapiens_hsa030203.01165163
4Steroid biosynthesis_Homo sapiens_hsa001002.90736652
5Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.74625987
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.70117440
7Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.68082459
8Maturity onset diabetes of the young_Homo sapiens_hsa049502.62258686
9Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005342.54766912
10Fanconi anemia pathway_Homo sapiens_hsa034602.30940201
11Fatty acid biosynthesis_Homo sapiens_hsa000612.21639715
12ABC transporters_Homo sapiens_hsa020102.18268050
13Butanoate metabolism_Homo sapiens_hsa006502.14588613
14Nucleotide excision repair_Homo sapiens_hsa034202.01164686
15Fatty acid metabolism_Homo sapiens_hsa012121.91006169
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.87703347
17Homologous recombination_Homo sapiens_hsa034401.87128877
18Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.86061787
19RNA degradation_Homo sapiens_hsa030181.82306228
20Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.77046444
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.71933002
22RNA transport_Homo sapiens_hsa030131.67683365
23Peroxisome_Homo sapiens_hsa041461.61673388
24Selenocompound metabolism_Homo sapiens_hsa004501.59973590
25Lysine degradation_Homo sapiens_hsa003101.59716657
26Protein export_Homo sapiens_hsa030601.58717938
27One carbon pool by folate_Homo sapiens_hsa006701.42244064
28Propanoate metabolism_Homo sapiens_hsa006401.42095022
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.39568493
30Pyrimidine metabolism_Homo sapiens_hsa002401.37446645
31Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.36156172
32Base excision repair_Homo sapiens_hsa034101.35699210
33Circadian rhythm_Homo sapiens_hsa047101.32674837
34Fatty acid elongation_Homo sapiens_hsa000621.24268423
35Cell cycle_Homo sapiens_hsa041101.21288415
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.21258954
37Mismatch repair_Homo sapiens_hsa034301.20266082
38Phototransduction_Homo sapiens_hsa047441.18666201
39Regulation of autophagy_Homo sapiens_hsa041401.16557681
40Ovarian steroidogenesis_Homo sapiens_hsa049131.07015742
41Complement and coagulation cascades_Homo sapiens_hsa046100.97277617
42Purine metabolism_Homo sapiens_hsa002300.96641566
43Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.96272797
44Taste transduction_Homo sapiens_hsa047420.87496370
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85583611
46p53 signaling pathway_Homo sapiens_hsa041150.85139226
47Glycosaminoglycan degradation_Homo sapiens_hsa005310.83870680
48FoxO signaling pathway_Homo sapiens_hsa040680.81192840
49Pyruvate metabolism_Homo sapiens_hsa006200.76541762
50N-Glycan biosynthesis_Homo sapiens_hsa005100.75658655
51Fatty acid degradation_Homo sapiens_hsa000710.75519914
52Tryptophan metabolism_Homo sapiens_hsa003800.75481647
53alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.74595151
54TGF-beta signaling pathway_Homo sapiens_hsa043500.73124062
55mTOR signaling pathway_Homo sapiens_hsa041500.72901806
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.71464454
57Insulin resistance_Homo sapiens_hsa049310.70337546
58Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70197179
59Adipocytokine signaling pathway_Homo sapiens_hsa049200.67374541
60mRNA surveillance pathway_Homo sapiens_hsa030150.62590579
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.60842951
62Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.60649111
63DNA replication_Homo sapiens_hsa030300.57895801
64Spliceosome_Homo sapiens_hsa030400.56384564
65Glucagon signaling pathway_Homo sapiens_hsa049220.56124538
66Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55331181
67Metabolic pathways_Homo sapiens_hsa011000.54341074
68Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.53208865
69RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.52483602
70Basal cell carcinoma_Homo sapiens_hsa052170.51264236
71Proteasome_Homo sapiens_hsa030500.50487456
72Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.49578710
73Insulin secretion_Homo sapiens_hsa049110.48912264
74PPAR signaling pathway_Homo sapiens_hsa033200.47564732
75Hippo signaling pathway_Homo sapiens_hsa043900.46121018
76Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46063562
77Sulfur metabolism_Homo sapiens_hsa009200.44206949
78Axon guidance_Homo sapiens_hsa043600.44051647
79Thyroid hormone synthesis_Homo sapiens_hsa049180.43788228
80Fat digestion and absorption_Homo sapiens_hsa049750.42926953
81Jak-STAT signaling pathway_Homo sapiens_hsa046300.42170490
82Small cell lung cancer_Homo sapiens_hsa052220.40440133
83Longevity regulating pathway - mammal_Homo sapiens_hsa042110.38874215
84Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37455078
85PI3K-Akt signaling pathway_Homo sapiens_hsa041510.37146504
86MicroRNAs in cancer_Homo sapiens_hsa052060.35825108
87Ether lipid metabolism_Homo sapiens_hsa005650.35542231
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.33810944
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33086035
90AMPK signaling pathway_Homo sapiens_hsa041520.32732973
91Nicotine addiction_Homo sapiens_hsa050330.30715136
92Steroid hormone biosynthesis_Homo sapiens_hsa001400.30457676
93Viral carcinogenesis_Homo sapiens_hsa052030.30223660
94Collecting duct acid secretion_Homo sapiens_hsa049660.29408638
95Primary immunodeficiency_Homo sapiens_hsa053400.26176505
96Olfactory transduction_Homo sapiens_hsa047400.23550667
97Hepatitis B_Homo sapiens_hsa051610.22313664
98Calcium signaling pathway_Homo sapiens_hsa040200.21904170
99Dopaminergic synapse_Homo sapiens_hsa047280.20696048
100Glycerolipid metabolism_Homo sapiens_hsa005610.20522173

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »