Rank | Gene Set | Z-score |
---|---|---|
1 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.97671059 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.51963394 |
3 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.46839340 |
4 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 4.42446925 |
5 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.13171416 |
6 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.74511321 |
7 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.62519293 |
8 | response to muramyl dipeptide (GO:0032495) | 3.58274325 |
9 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.50528737 |
10 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.50528737 |
11 | modulation by symbiont of host immune response (GO:0052553) | 3.50528737 |
12 | positive regulation by symbiont of host defense response (GO:0052509) | 3.50528737 |
13 | modulation by symbiont of host defense response (GO:0052031) | 3.50528737 |
14 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.50528737 |
15 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.24532889 |
16 | regulation of histone H3-K27 methylation (GO:0061085) | 3.23755143 |
17 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.23314358 |
18 | mannose metabolic process (GO:0006013) | 3.20671020 |
19 | modulation by virus of host process (GO:0019054) | 3.20597423 |
20 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.16979443 |
21 | negative regulation of cell killing (GO:0031342) | 3.16979443 |
22 | mRNA stabilization (GO:0048255) | 3.16130109 |
23 | RNA stabilization (GO:0043489) | 3.16130109 |
24 | positive thymic T cell selection (GO:0045059) | 3.09827315 |
25 | modulation by symbiont of host cellular process (GO:0044068) | 3.05828623 |
26 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.02613377 |
27 | response to peptidoglycan (GO:0032494) | 3.02283010 |
28 | response to laminar fluid shear stress (GO:0034616) | 3.00740594 |
29 | thymic T cell selection (GO:0045061) | 3.00555897 |
30 | regulation of gamma-delta T cell activation (GO:0046643) | 2.98184636 |
31 | embryonic process involved in female pregnancy (GO:0060136) | 2.98002862 |
32 | histone H3-K36 demethylation (GO:0070544) | 2.95184756 |
33 | NIK/NF-kappaB signaling (GO:0038061) | 2.94120545 |
34 | leukocyte aggregation (GO:0070486) | 2.91776535 |
35 | apoptotic process involved in morphogenesis (GO:0060561) | 2.89886263 |
36 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.88669058 |
37 | germinal center formation (GO:0002467) | 2.88192223 |
38 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.87827495 |
39 | cellular response to virus (GO:0098586) | 2.83180701 |
40 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.80802690 |
41 | detection of bacterium (GO:0016045) | 2.80149739 |
42 | COPI coating of Golgi vesicle (GO:0048205) | 2.77057216 |
43 | Golgi transport vesicle coating (GO:0048200) | 2.77057216 |
44 | detection of other organism (GO:0098543) | 2.72809562 |
45 | adherens junction assembly (GO:0034333) | 2.72381833 |
46 | cell-substrate adherens junction assembly (GO:0007045) | 2.72104746 |
47 | focal adhesion assembly (GO:0048041) | 2.72104746 |
48 | mitotic chromosome condensation (GO:0007076) | 2.71989168 |
49 | regulation of RNA export from nucleus (GO:0046831) | 2.69033694 |
50 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.67253204 |
51 | response to host (GO:0075136) | 2.66267802 |
52 | response to host defenses (GO:0052200) | 2.66267802 |
53 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.66267802 |
54 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.63384041 |
55 | negative thymic T cell selection (GO:0045060) | 2.60989526 |
56 | macrophage activation involved in immune response (GO:0002281) | 2.59592202 |
57 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.59169920 |
58 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.57877554 |
59 | trophectodermal cell differentiation (GO:0001829) | 2.55853606 |
60 | maternal placenta development (GO:0001893) | 2.54108760 |
61 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.53933141 |
62 | megakaryocyte development (GO:0035855) | 2.53884133 |
63 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.53002720 |
64 | histone lysine demethylation (GO:0070076) | 2.52384676 |
65 | activation of Rac GTPase activity (GO:0032863) | 2.51344405 |
66 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.51090494 |
67 | pinocytosis (GO:0006907) | 2.50448862 |
68 | T cell selection (GO:0045058) | 2.49530647 |
69 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.48789619 |
70 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.48731550 |
71 | protein localization to endosome (GO:0036010) | 2.48670623 |
72 | tolerance induction (GO:0002507) | 2.48541702 |
73 | pentose-phosphate shunt (GO:0006098) | 2.47510196 |
74 | response to host immune response (GO:0052572) | 2.46735665 |
75 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.46735665 |
76 | negative regulation of myotube differentiation (GO:0010832) | 2.45212618 |
77 | modulation by virus of host morphology or physiology (GO:0019048) | 2.45017917 |
78 | negative regulation of histone methylation (GO:0031061) | 2.44960547 |
79 | signal complex assembly (GO:0007172) | 2.43947599 |
80 | negative regulation of cell size (GO:0045792) | 2.42796134 |
81 | positive regulation of histone deacetylation (GO:0031065) | 2.42408706 |
82 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 2.42072609 |
83 | cellular response to interleukin-4 (GO:0071353) | 2.41576748 |
84 | histone H3-K4 methylation (GO:0051568) | 2.39036538 |
85 | regulation of chromatin binding (GO:0035561) | 2.38813240 |
86 | histone H4 deacetylation (GO:0070933) | 2.37647543 |
87 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.37166052 |
88 | B cell receptor signaling pathway (GO:0050853) | 2.36543423 |
89 | histone demethylation (GO:0016577) | 2.36509315 |
90 | negative regulation of viral release from host cell (GO:1902187) | 2.36204772 |
91 | regulation of ARF GTPase activity (GO:0032312) | 2.34032979 |
92 | negative T cell selection (GO:0043383) | 2.33119767 |
93 | stress fiber assembly (GO:0043149) | 2.32949757 |
94 | regulation of leukocyte degranulation (GO:0043300) | 2.31749195 |
95 | histone H3-K9 demethylation (GO:0033169) | 2.30984718 |
96 | nucleosome disassembly (GO:0006337) | 2.30566920 |
97 | protein-DNA complex disassembly (GO:0032986) | 2.30566920 |
98 | positive T cell selection (GO:0043368) | 2.29522873 |
99 | regulation of glucose import in response to insulin stimulus (GO:2001273) | 2.28648145 |
100 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.27992920 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MYC_22102868_ChIP-Seq_BL_Human | 3.69738326 |
2 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.18144927 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.93328358 |
4 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.82760035 |
5 | TCF7_22412390_ChIP-Seq_EML_Mouse | 2.56666366 |
6 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 2.51014762 |
7 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.48743890 |
8 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.41798400 |
9 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.29274257 |
10 | LXR_22292898_ChIP-Seq_THP-1_Human | 2.28357177 |
11 | KDM2B_26808549_Chip-Seq_DND41_Human | 2.25692588 |
12 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 2.24544244 |
13 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.12955894 |
14 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.04941494 |
15 | MAF_26560356_Chip-Seq_TH1_Human | 2.02043139 |
16 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 2.00171328 |
17 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.91854898 |
18 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.89884929 |
19 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.86570219 |
20 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.79035912 |
21 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.77537267 |
22 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.76268388 |
23 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.72035823 |
24 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.66613709 |
25 | MAF_26560356_Chip-Seq_TH2_Human | 1.64292431 |
26 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.63378494 |
27 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.62342172 |
28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.61941588 |
29 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.57970818 |
30 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.57155482 |
31 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.56669420 |
32 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.53166901 |
33 | KDM2B_26808549_Chip-Seq_K562_Human | 1.52129460 |
34 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.51182375 |
35 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.49872434 |
36 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.48430639 |
37 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.43783175 |
38 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.42905546 |
39 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.40908465 |
40 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.38736568 |
41 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.38680483 |
42 | * KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.37555466 |
43 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.37459562 |
44 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.36885799 |
45 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.33951105 |
46 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.32934068 |
47 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.32446432 |
48 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.31672055 |
49 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.31627209 |
50 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.31350640 |
51 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.30473663 |
52 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.30069071 |
53 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.29259479 |
54 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.29224864 |
55 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28967292 |
56 | P68_20966046_ChIP-Seq_HELA_Human | 1.28663033 |
57 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.28067241 |
58 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.26804048 |
59 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.26586272 |
60 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.25284629 |
61 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.22231295 |
62 | MYB_26560356_Chip-Seq_TH1_Human | 1.22044234 |
63 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.21881785 |
64 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.21784224 |
65 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.21575567 |
66 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.21382610 |
67 | SMC4_20622854_ChIP-Seq_HELA_Human | 1.20331925 |
68 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.20092871 |
69 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.19381658 |
70 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.19109446 |
71 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.17546719 |
72 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.15985094 |
73 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.15615660 |
74 | SPI1_23127762_ChIP-Seq_K562_Human | 1.15211369 |
75 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.13592672 |
76 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.13282330 |
77 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.13143964 |
78 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.12935289 |
79 | * SPI1_23547873_ChIP-Seq_NB4_Human | 1.12899680 |
80 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.12804541 |
81 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.12013523 |
82 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07827297 |
83 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.06662226 |
84 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.06395236 |
85 | MYB_26560356_Chip-Seq_TH2_Human | 1.06224916 |
86 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04962030 |
87 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.04099698 |
88 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.02844169 |
89 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.02789879 |
90 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.02479661 |
91 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.01726614 |
92 | * RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.01533543 |
93 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.01237349 |
94 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.00536361 |
95 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.99506837 |
96 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.99176778 |
97 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.98408216 |
98 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.98243114 |
99 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.96813717 |
100 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96780452 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003436_decreased_susceptibility_to | 3.36237685 |
2 | MP0003705_abnormal_hypodermis_morpholog | 3.03928040 |
3 | MP0009278_abnormal_bone_marrow | 2.70726653 |
4 | MP0005076_abnormal_cell_differentiation | 2.68989289 |
5 | MP0003303_peritoneal_inflammation | 2.65241619 |
6 | MP0003763_abnormal_thymus_physiology | 2.55742122 |
7 | MP0005451_abnormal_body_composition | 2.44676991 |
8 | MP0002396_abnormal_hematopoietic_system | 2.18558255 |
9 | MP0003300_gastrointestinal_ulcer | 2.05272859 |
10 | MP0002877_abnormal_melanocyte_morpholog | 2.02969114 |
11 | MP0008260_abnormal_autophagy | 1.94344836 |
12 | MP0001835_abnormal_antigen_presentation | 1.89387732 |
13 | MP0004947_skin_inflammation | 1.85101759 |
14 | MP0004808_abnormal_hematopoietic_stem | 1.84790598 |
15 | MP0009333_abnormal_splenocyte_physiolog | 1.84325332 |
16 | MP0000685_abnormal_immune_system | 1.83438746 |
17 | MP0001849_ear_inflammation | 1.80925955 |
18 | MP0002009_preneoplasia | 1.78721872 |
19 | MP0005058_abnormal_lysosome_morphology | 1.77707425 |
20 | MP0001800_abnormal_humoral_immune | 1.74297166 |
21 | MP0005000_abnormal_immune_tolerance | 1.72339693 |
22 | MP0002398_abnormal_bone_marrow | 1.70170205 |
23 | MP0000703_abnormal_thymus_morphology | 1.66142582 |
24 | MP0003172_abnormal_lysosome_physiology | 1.65754192 |
25 | MP0003566_abnormal_cell_adhesion | 1.63692747 |
26 | MP0002419_abnormal_innate_immunity | 1.63279165 |
27 | MP0004185_abnormal_adipocyte_glucose | 1.62899408 |
28 | MP0005025_abnormal_response_to | 1.61668694 |
29 | MP0009840_abnormal_foam_cell | 1.59281450 |
30 | MP0005387_immune_system_phenotype | 1.58573871 |
31 | MP0001790_abnormal_immune_system | 1.58573871 |
32 | MP0002420_abnormal_adaptive_immunity | 1.57287990 |
33 | MP0004858_abnormal_nervous_system | 1.56379561 |
34 | MP0001819_abnormal_immune_cell | 1.55684069 |
35 | MP0004264_abnormal_extraembryonic_tissu | 1.55027289 |
36 | MP0002723_abnormal_immune_serum | 1.54639484 |
37 | MP0003091_abnormal_cell_migration | 1.54027044 |
38 | MP0003191_abnormal_cellular_cholesterol | 1.52709045 |
39 | MP0002452_abnormal_antigen_presenting | 1.49449926 |
40 | MP0000858_altered_metastatic_potential | 1.49091477 |
41 | MP0000716_abnormal_immune_system | 1.41972316 |
42 | MP0001533_abnormal_skeleton_physiology | 1.36895527 |
43 | MP0002722_abnormal_immune_system | 1.36570564 |
44 | MP0003111_abnormal_nucleus_morphology | 1.34070681 |
45 | MP0005409_darkened_coat_color | 1.33872825 |
46 | MP0005666_abnormal_adipose_tissue | 1.33566660 |
47 | MP0003453_abnormal_keratinocyte_physiol | 1.33090403 |
48 | MP0005671_abnormal_response_to | 1.32238829 |
49 | MP0001348_abnormal_lacrimal_gland | 1.32108916 |
50 | MP0002405_respiratory_system_inflammati | 1.31536477 |
51 | MP0002429_abnormal_blood_cell | 1.29483167 |
52 | MP0001873_stomach_inflammation | 1.29294313 |
53 | MP0002998_abnormal_bone_remodeling | 1.28611731 |
54 | MP0002166_altered_tumor_susceptibility | 1.26209005 |
55 | MP0000490_abnormal_crypts_of | 1.26033121 |
56 | MP0005375_adipose_tissue_phenotype | 1.23544067 |
57 | MP0010155_abnormal_intestine_physiology | 1.22057738 |
58 | MP0000003_abnormal_adipose_tissue | 1.20888854 |
59 | MP0005397_hematopoietic_system_phenotyp | 1.17326179 |
60 | MP0001545_abnormal_hematopoietic_system | 1.17326179 |
61 | MP0001730_embryonic_growth_arrest | 1.17317247 |
62 | MP0000350_abnormal_cell_proliferation | 1.16410865 |
63 | MP0000689_abnormal_spleen_morphology | 1.15701519 |
64 | MP0003828_pulmonary_edema | 1.11293690 |
65 | MP0003279_aneurysm | 1.09691398 |
66 | MP0001851_eye_inflammation | 1.08786780 |
67 | MP0002249_abnormal_larynx_morphology | 1.08434161 |
68 | MP0000733_abnormal_muscle_development | 1.06438552 |
69 | MP0000678_abnormal_parathyroid_gland | 1.05913856 |
70 | MP0004510_myositis | 1.05054516 |
71 | MP0004381_abnormal_hair_follicle | 1.04948045 |
72 | MP0005621_abnormal_cell_physiology | 1.04830665 |
73 | MP0002089_abnormal_postnatal_growth/wei | 1.00066117 |
74 | MP0008438_abnormal_cutaneous_collagen | 0.96442651 |
75 | MP0004233_abnormal_muscle_weight | 0.93808375 |
76 | MP0005257_abnormal_intraocular_pressure | 0.93607421 |
77 | MP0005464_abnormal_platelet_physiology | 0.93111772 |
78 | MP0009115_abnormal_fat_cell | 0.91491419 |
79 | MP0000313_abnormal_cell_death | 0.91462067 |
80 | MP0003724_increased_susceptibility_to | 0.90338911 |
81 | MP0000767_abnormal_smooth_muscle | 0.90033746 |
82 | MP0003693_abnormal_embryo_hatching | 0.89912799 |
83 | MP0002796_impaired_skin_barrier | 0.89739634 |
84 | MP0003183_abnormal_peptide_metabolism | 0.89067760 |
85 | MP0009931_abnormal_skin_appearance | 0.88664906 |
86 | MP0003077_abnormal_cell_cycle | 0.88271827 |
87 | MP0003115_abnormal_respiratory_system | 0.87210386 |
88 | MP0010352_gastrointestinal_tract_polyps | 0.86076120 |
89 | MP0005390_skeleton_phenotype | 0.84594728 |
90 | MP0003984_embryonic_growth_retardation | 0.84224670 |
91 | MP0003866_abnormal_defecation | 0.83931312 |
92 | MP0001845_abnormal_inflammatory_respons | 0.83716673 |
93 | MP0003656_abnormal_erythrocyte_physiolo | 0.83492420 |
94 | MP0001853_heart_inflammation | 0.82757307 |
95 | MP0010630_abnormal_cardiac_muscle | 0.82218884 |
96 | MP0008961_abnormal_basal_metabolism | 0.81358844 |
97 | MP0002933_joint_inflammation | 0.81070398 |
98 | MP0002019_abnormal_tumor_incidence | 0.78924036 |
99 | MP0009785_altered_susceptibility_to | 0.78305410 |
100 | MP0002080_prenatal_lethality | 0.77486045 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Eczematoid dermatitis (HP:0000976) | 3.52360819 |
2 | Abnormality of the fingertips (HP:0001211) | 3.49933213 |
3 | Obstructive sleep apnea (HP:0002870) | 3.20947404 |
4 | Hyperacusis (HP:0010780) | 2.90387922 |
5 | Increased IgE level (HP:0003212) | 2.84894958 |
6 | Cellulitis (HP:0100658) | 2.71915123 |
7 | Broad face (HP:0000283) | 2.68524701 |
8 | Recurrent abscess formation (HP:0002722) | 2.58110961 |
9 | Recurrent bacterial skin infections (HP:0005406) | 2.50762249 |
10 | Disproportionate tall stature (HP:0001519) | 2.41352107 |
11 | Gastrointestinal stroma tumor (HP:0100723) | 2.37491506 |
12 | Protrusio acetabuli (HP:0003179) | 2.29007771 |
13 | Colitis (HP:0002583) | 2.28319259 |
14 | Abnormality of macrophages (HP:0004311) | 2.24233296 |
15 | Distal lower limb amyotrophy (HP:0008944) | 2.22730285 |
16 | Spinal cord lesions (HP:0100561) | 2.22368375 |
17 | Syringomyelia (HP:0003396) | 2.22368375 |
18 | Recurrent viral infections (HP:0004429) | 2.20909066 |
19 | Asymmetry of the thorax (HP:0001555) | 2.18384812 |
20 | Long eyelashes (HP:0000527) | 2.17597945 |
21 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.15964064 |
22 | Flat acetabular roof (HP:0003180) | 2.14714746 |
23 | Cerebral aneurysm (HP:0004944) | 2.11542849 |
24 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.10889805 |
25 | Emphysema (HP:0002097) | 2.10281468 |
26 | Gastrointestinal inflammation (HP:0004386) | 2.09993199 |
27 | Long palpebral fissure (HP:0000637) | 2.07844546 |
28 | Metaphyseal cupping (HP:0003021) | 2.07463309 |
29 | Agammaglobulinemia (HP:0004432) | 2.05833167 |
30 | Mediastinal lymphadenopathy (HP:0100721) | 2.05656822 |
31 | Vertebral compression fractures (HP:0002953) | 2.05495510 |
32 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.03668841 |
33 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.00283457 |
34 | Thin bony cortex (HP:0002753) | 1.98633174 |
35 | Recurrent fungal infections (HP:0002841) | 1.96143984 |
36 | Meningitis (HP:0001287) | 1.95955884 |
37 | Abnormality of the columella (HP:0009929) | 1.94117836 |
38 | Hemorrhage of the eye (HP:0011885) | 1.93503177 |
39 | Dislocated radial head (HP:0003083) | 1.92161784 |
40 | Spontaneous hematomas (HP:0007420) | 1.91422654 |
41 | Fatigue (HP:0012378) | 1.89875638 |
42 | Shallow orbits (HP:0000586) | 1.88715367 |
43 | Increased connective tissue (HP:0009025) | 1.87697451 |
44 | Sparse lateral eyebrow (HP:0005338) | 1.87011603 |
45 | Chronic obstructive pulmonary disease (HP:0006510) | 1.84517723 |
46 | Obstructive lung disease (HP:0006536) | 1.84517723 |
47 | Easy fatigability (HP:0003388) | 1.83730652 |
48 | Gastrointestinal infarctions (HP:0005244) | 1.82194091 |
49 | Inflammation of the large intestine (HP:0002037) | 1.81726405 |
50 | Cervical subluxation (HP:0003308) | 1.81260234 |
51 | Slow saccadic eye movements (HP:0000514) | 1.80545241 |
52 | Gingivitis (HP:0000230) | 1.78471687 |
53 | Panhypogammaglobulinemia (HP:0003139) | 1.78301450 |
54 | Neuronal loss in central nervous system (HP:0002529) | 1.77449593 |
55 | Turricephaly (HP:0000262) | 1.77146602 |
56 | Polygenic inheritance (HP:0010982) | 1.76446758 |
57 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.75482751 |
58 | Broad distal phalanx of finger (HP:0009836) | 1.75289968 |
59 | Abnormality of the radial head (HP:0003995) | 1.74807949 |
60 | Viral hepatitis (HP:0006562) | 1.74562212 |
61 | Supernumerary ribs (HP:0005815) | 1.73718099 |
62 | Deep palmar crease (HP:0006191) | 1.73083621 |
63 | Abnormality of the thoracic spine (HP:0100711) | 1.72992651 |
64 | Urticaria (HP:0001025) | 1.72300952 |
65 | Myositis (HP:0100614) | 1.72095226 |
66 | Ulnar bowing (HP:0003031) | 1.69204919 |
67 | Spondylolisthesis (HP:0003302) | 1.68735272 |
68 | Aneurysm (HP:0002617) | 1.65838896 |
69 | Vasculitis (HP:0002633) | 1.64525691 |
70 | Biconcave vertebral bodies (HP:0004586) | 1.63912416 |
71 | Granulocytopenia (HP:0001913) | 1.63574145 |
72 | Recurrent skin infections (HP:0001581) | 1.63194346 |
73 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.61429506 |
74 | Recurrent cutaneous fungal infections (HP:0011370) | 1.61429506 |
75 | Supernumerary nipples (HP:0002558) | 1.61358561 |
76 | Pustule (HP:0200039) | 1.60301536 |
77 | Premature skin wrinkling (HP:0100678) | 1.59208620 |
78 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.58456731 |
79 | Papilloma (HP:0012740) | 1.58112697 |
80 | Verrucae (HP:0200043) | 1.58112697 |
81 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.57924295 |
82 | Thoracic kyphosis (HP:0002942) | 1.56411202 |
83 | Trigonocephaly (HP:0000243) | 1.55668383 |
84 | Ankyloglossia (HP:0010296) | 1.55241196 |
85 | Germ cell neoplasia (HP:0100728) | 1.53673648 |
86 | Insomnia (HP:0100785) | 1.52106525 |
87 | Abnormality of the peritoneum (HP:0002585) | 1.51207580 |
88 | Thin ribs (HP:0000883) | 1.50855396 |
89 | Persistence of primary teeth (HP:0006335) | 1.49751274 |
90 | Cholecystitis (HP:0001082) | 1.49580264 |
91 | Abnormal gallbladder physiology (HP:0012438) | 1.49580264 |
92 | Lymphopenia (HP:0001888) | 1.49561088 |
93 | Broad palm (HP:0001169) | 1.48765435 |
94 | Dysostosis multiplex (HP:0000943) | 1.47813763 |
95 | Flattened epiphyses (HP:0003071) | 1.47767440 |
96 | Dilatation of the ascending aorta (HP:0005111) | 1.47166096 |
97 | Distal upper limb amyotrophy (HP:0007149) | 1.46853806 |
98 | Upper limb amyotrophy (HP:0009129) | 1.46853806 |
99 | Achilles tendon contracture (HP:0001771) | 1.46540455 |
100 | Restrictive lung disease (HP:0002091) | 1.45786630 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 4.31886179 |
2 | PRPF4B | 3.90358412 |
3 | CDK12 | 3.73485102 |
4 | ERN1 | 3.57270075 |
5 | SMG1 | 3.29078462 |
6 | SIK1 | 2.52009140 |
7 | ICK | 2.33267057 |
8 | MAP4K1 | 2.19817005 |
9 | MAP3K13 | 2.17326740 |
10 | MAP3K10 | 2.16572969 |
11 | MAP2K3 | 2.03066325 |
12 | FGFR4 | 1.94461785 |
13 | RIPK4 | 1.92787875 |
14 | EEF2K | 1.90981411 |
15 | SIK3 | 1.64101660 |
16 | IRAK3 | 1.58367712 |
17 | SIK2 | 1.56499622 |
18 | RIPK1 | 1.53636262 |
19 | MAP3K14 | 1.51981215 |
20 | IRAK4 | 1.42516416 |
21 | CDC42BPA | 1.28122711 |
22 | EPHB1 | 1.24035943 |
23 | ZAP70 | 1.21657574 |
24 | PRKD2 | 1.19276105 |
25 | CDK4 | 1.17802145 |
26 | MARK2 | 1.15904045 |
27 | TYK2 | 1.13882871 |
28 | TAOK2 | 1.10314620 |
29 | TESK2 | 1.09691079 |
30 | KSR2 | 1.07484889 |
31 | PDGFRA | 1.05120242 |
32 | PKN2 | 1.03069733 |
33 | JAK3 | 1.01599509 |
34 | TBK1 | 1.01406194 |
35 | TAOK1 | 1.01327544 |
36 | MAP3K7 | 1.00502709 |
37 | GRK6 | 0.99433494 |
38 | MTOR | 0.98820390 |
39 | MAP3K3 | 0.98506544 |
40 | BRD4 | 0.97843844 |
41 | NME2 | 0.93442774 |
42 | PTK6 | 0.91823643 |
43 | CAMK1D | 0.91628540 |
44 | MAP3K6 | 0.90071814 |
45 | TNK2 | 0.88760703 |
46 | BTK | 0.86283819 |
47 | LRRK2 | 0.85077599 |
48 | CDK6 | 0.80820324 |
49 | CSK | 0.78707850 |
50 | HIPK2 | 0.77110343 |
51 | CDK7 | 0.76697942 |
52 | BLK | 0.75290634 |
53 | HCK | 0.74816499 |
54 | PDPK1 | 0.73871999 |
55 | MAPK11 | 0.73712613 |
56 | FGFR3 | 0.72159872 |
57 | TYRO3 | 0.72153719 |
58 | PAK4 | 0.70937491 |
59 | EPHA2 | 0.69811080 |
60 | MAP3K1 | 0.69080275 |
61 | FES | 0.68618717 |
62 | MAP2K2 | 0.67117601 |
63 | STK10 | 0.65795133 |
64 | MAP3K8 | 0.65530705 |
65 | IKBKE | 0.64473633 |
66 | JAK1 | 0.63513964 |
67 | RET | 0.63096674 |
68 | BMX | 0.63062407 |
69 | IRAK2 | 0.60321464 |
70 | TTN | 0.59576713 |
71 | CDK9 | 0.59321866 |
72 | RPS6KC1 | 0.58711616 |
73 | RPS6KL1 | 0.58711616 |
74 | FGR | 0.58360595 |
75 | MELK | 0.57962402 |
76 | MAPK12 | 0.53619918 |
77 | PRKD3 | 0.52928027 |
78 | MARK3 | 0.51786097 |
79 | RPS6KA2 | 0.51651237 |
80 | PDK1 | 0.51177330 |
81 | PTK2 | 0.49395634 |
82 | MATK | 0.48959502 |
83 | CHUK | 0.46518992 |
84 | PDGFRB | 0.46147736 |
85 | PASK | 0.45841359 |
86 | KIT | 0.43968848 |
87 | LCK | 0.43736473 |
88 | DYRK1B | 0.43095898 |
89 | CSF1R | 0.42368277 |
90 | CAMKK1 | 0.42112675 |
91 | YES1 | 0.40930432 |
92 | CAMK1G | 0.40609957 |
93 | SGK3 | 0.40553030 |
94 | MAPK7 | 0.39783132 |
95 | RPS6KA6 | 0.39052608 |
96 | SYK | 0.38624513 |
97 | WNK1 | 0.36236268 |
98 | JAK2 | 0.36228515 |
99 | MOS | 0.35413125 |
100 | RPS6KA1 | 0.34808172 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 2.34023709 |
2 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 2.16923118 |
3 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.06693727 |
4 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 2.02726037 |
5 | Other glycan degradation_Homo sapiens_hsa00511 | 1.97602887 |
6 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.83333810 |
7 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.77818534 |
8 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.74249024 |
9 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.73871866 |
10 | Leishmaniasis_Homo sapiens_hsa05140 | 1.54964669 |
11 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.52303855 |
12 | Hepatitis B_Homo sapiens_hsa05161 | 1.51404920 |
13 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.49519980 |
14 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.48322218 |
15 | Endometrial cancer_Homo sapiens_hsa05213 | 1.46415397 |
16 | Bladder cancer_Homo sapiens_hsa05219 | 1.41736157 |
17 | Thyroid cancer_Homo sapiens_hsa05216 | 1.41538896 |
18 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.40171205 |
19 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.39559981 |
20 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.37857164 |
21 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.37361515 |
22 | Prostate cancer_Homo sapiens_hsa05215 | 1.37337849 |
23 | Influenza A_Homo sapiens_hsa05164 | 1.36337366 |
24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.36319627 |
25 | Measles_Homo sapiens_hsa05162 | 1.30230912 |
26 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.29021706 |
27 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.27024943 |
28 | Hepatitis C_Homo sapiens_hsa05160 | 1.25913069 |
29 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.25208022 |
30 | Colorectal cancer_Homo sapiens_hsa05210 | 1.20920265 |
31 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.19725982 |
32 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.18488157 |
33 | Apoptosis_Homo sapiens_hsa04210 | 1.18250319 |
34 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.17885670 |
35 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.16395944 |
36 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.15168029 |
37 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.13888083 |
38 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.11592792 |
39 | Glioma_Homo sapiens_hsa05214 | 1.11147636 |
40 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.10447237 |
41 | Tuberculosis_Homo sapiens_hsa05152 | 1.08124166 |
42 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.07037720 |
43 | HTLV-I infection_Homo sapiens_hsa05166 | 1.06316108 |
44 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.03679304 |
45 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.01621645 |
46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.01613945 |
47 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 1.00800209 |
48 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.96933844 |
49 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.96747680 |
50 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.95123204 |
51 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.94954303 |
52 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.93351619 |
53 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.92823802 |
54 | Viral myocarditis_Homo sapiens_hsa05416 | 0.92157646 |
55 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.92027233 |
56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.91792278 |
57 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.89648126 |
58 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.89568042 |
59 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.88856248 |
60 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.85884799 |
61 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.84933672 |
62 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.83730741 |
63 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.82329074 |
64 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.82303986 |
65 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.82015527 |
66 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.81546180 |
67 | Shigellosis_Homo sapiens_hsa05131 | 0.80852900 |
68 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.80241694 |
69 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.78405592 |
70 | Insulin resistance_Homo sapiens_hsa04931 | 0.77687981 |
71 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.77666063 |
72 | Endocytosis_Homo sapiens_hsa04144 | 0.75805210 |
73 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.75695514 |
74 | Allograft rejection_Homo sapiens_hsa05330 | 0.75003245 |
75 | Malaria_Homo sapiens_hsa05144 | 0.74507352 |
76 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.74145658 |
77 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.73938005 |
78 | Prion diseases_Homo sapiens_hsa05020 | 0.73711522 |
79 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.73481978 |
80 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.72815938 |
81 | Spliceosome_Homo sapiens_hsa03040 | 0.71210460 |
82 | Amoebiasis_Homo sapiens_hsa05146 | 0.70984689 |
83 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.70423398 |
84 | Lysine degradation_Homo sapiens_hsa00310 | 0.69709006 |
85 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.68350514 |
86 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.66340433 |
87 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.66297858 |
88 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.65626109 |
89 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.64460157 |
90 | Platelet activation_Homo sapiens_hsa04611 | 0.63966252 |
91 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.63754766 |
92 | Adherens junction_Homo sapiens_hsa04520 | 0.63136161 |
93 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.62405796 |
94 | Focal adhesion_Homo sapiens_hsa04510 | 0.59559488 |
95 | Base excision repair_Homo sapiens_hsa03410 | 0.58822163 |
96 | Pathways in cancer_Homo sapiens_hsa05200 | 0.57887483 |
97 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.56356230 |
98 | Legionellosis_Homo sapiens_hsa05134 | 0.55277995 |
99 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.53682333 |
100 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.52247819 |