ZNF391

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intraciliary transport (GO:0042073)3.55820306
2presynaptic membrane assembly (GO:0097105)3.52785718
3synapsis (GO:0007129)3.43259901
4cilium or flagellum-dependent cell motility (GO:0001539)3.26536873
5resolution of meiotic recombination intermediates (GO:0000712)3.22363031
6presynaptic membrane organization (GO:0097090)3.17991458
7DNA double-strand break processing (GO:0000729)3.13236449
8pyrimidine nucleobase catabolic process (GO:0006208)3.11139514
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.09544552
10positive regulation of mitochondrial fission (GO:0090141)2.97981527
11purine nucleobase biosynthetic process (GO:0009113)2.86954422
12epithelial cilium movement (GO:0003351)2.81281044
13L-serine metabolic process (GO:0006563)2.79613910
14protein-cofactor linkage (GO:0018065)2.76583368
15nonmotile primary cilium assembly (GO:0035058)2.75622819
16proteasome assembly (GO:0043248)2.74872241
17reciprocal meiotic recombination (GO:0007131)2.70756385
18reciprocal DNA recombination (GO:0035825)2.70756385
19chromatin remodeling at centromere (GO:0031055)2.69851116
20somatic diversification of immune receptors via somatic mutation (GO:0002566)2.67597922
21somatic hypermutation of immunoglobulin genes (GO:0016446)2.67597922
22CENP-A containing nucleosome assembly (GO:0034080)2.61863959
23establishment of integrated proviral latency (GO:0075713)2.60396509
24axonemal dynein complex assembly (GO:0070286)2.59158176
25cholesterol biosynthetic process (GO:0006695)2.58006074
26DNA replication checkpoint (GO:0000076)2.57987501
27nuclear pore organization (GO:0006999)2.57849685
28DNA integration (GO:0015074)2.56814896
29cilium morphogenesis (GO:0060271)2.56089264
30cilium assembly (GO:0042384)2.54268156
31centriole replication (GO:0007099)2.51474540
32cilium organization (GO:0044782)2.51432051
33nucleobase biosynthetic process (GO:0046112)2.51338456
34negative regulation of DNA recombination (GO:0045910)2.50802372
35neuron cell-cell adhesion (GO:0007158)2.49828129
36postsynaptic membrane organization (GO:0001941)2.47712872
37male meiosis I (GO:0007141)2.47634465
38ribonucleoprotein complex disassembly (GO:0032988)2.47327651
39piRNA metabolic process (GO:0034587)2.47308237
40nuclear pore complex assembly (GO:0051292)2.46645231
41cilium movement (GO:0003341)2.46105937
42nucleobase catabolic process (GO:0046113)2.44085222
43regulation of cilium movement (GO:0003352)2.43920809
44histone H2A acetylation (GO:0043968)2.43189159
45isoprenoid biosynthetic process (GO:0008299)2.38878093
46IMP biosynthetic process (GO:0006188)2.37584566
47mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.37289103
48positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.37289103
49organelle disassembly (GO:1903008)2.36936053
50DNA methylation involved in gamete generation (GO:0043046)2.35950944
51chromosome organization involved in meiosis (GO:0070192)2.35775009
52retinal ganglion cell axon guidance (GO:0031290)2.35696490
53sterol biosynthetic process (GO:0016126)2.34398386
54regulation of meiosis I (GO:0060631)2.34290490
55histone exchange (GO:0043486)2.34008783
56maturation of 5.8S rRNA (GO:0000460)2.33339241
57establishment of mitochondrion localization (GO:0051654)2.30006202
58regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.29243627
59intra-S DNA damage checkpoint (GO:0031573)2.28240231
60photoreceptor cell maintenance (GO:0045494)2.28078638
61positive regulation of RNA splicing (GO:0033120)2.25915282
62protein localization to synapse (GO:0035418)2.25796872
63regulation of centriole replication (GO:0046599)2.24851264
64protein polyglutamylation (GO:0018095)2.22935206
65behavioral response to nicotine (GO:0035095)2.22051524
66tRNA aminoacylation for protein translation (GO:0006418)2.21296446
67V(D)J recombination (GO:0033151)2.21194929
68exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.21129977
69protein localization to kinetochore (GO:0034501)2.20693586
70gamma-aminobutyric acid transport (GO:0015812)2.19318921
71tRNA aminoacylation (GO:0043039)2.19241760
72amino acid activation (GO:0043038)2.19241760
73gene silencing by RNA (GO:0031047)2.18738321
74mitotic metaphase plate congression (GO:0007080)2.18491397
75calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.18108203
76cullin deneddylation (GO:0010388)2.18091200
77male meiosis (GO:0007140)2.17869728
78nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.17503797
79DNA damage response, detection of DNA damage (GO:0042769)2.16626056
80protein localization to cilium (GO:0061512)2.15211956
81transmission of nerve impulse (GO:0019226)2.15101584
82regulation of helicase activity (GO:0051095)2.14552042
83negative regulation of membrane potential (GO:0045837)2.13490415
84regulation of mitotic spindle checkpoint (GO:1903504)2.13285406
85regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.13285406
86replication fork processing (GO:0031297)2.11759144
87vocalization behavior (GO:0071625)2.11128882
88sister chromatid segregation (GO:0000819)2.10846078
89DNA replication-independent nucleosome organization (GO:0034724)2.10273475
90DNA replication-independent nucleosome assembly (GO:0006336)2.10273475
91behavioral response to cocaine (GO:0048148)2.10238364
92microtubule polymerization or depolymerization (GO:0031109)2.10196006
93establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.09995931
94mitochondrion transport along microtubule (GO:0047497)2.09995931
95meiotic cell cycle process (GO:1903046)2.09883941
96double-strand break repair via nonhomologous end joining (GO:0006303)2.09856586
97non-recombinational repair (GO:0000726)2.09856586
98regulation of microtubule-based movement (GO:0060632)2.09277126
99axoneme assembly (GO:0035082)2.08941726
100regulation of translation, ncRNA-mediated (GO:0045974)2.08751656

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RBPJ_22232070_ChIP-Seq_NCS_Mouse4.76877584
2ZNF274_21170338_ChIP-Seq_K562_Hela3.07804937
3IGF1R_20145208_ChIP-Seq_DFB_Human3.05716297
4GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.02870904
5SALL1_21062744_ChIP-ChIP_HESCs_Human2.60933832
6EZH2_22144423_ChIP-Seq_EOC_Human2.59126903
7FUS_26573619_Chip-Seq_HEK293_Human2.48878302
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.48037223
9MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.31808410
10EWS_26573619_Chip-Seq_HEK293_Human2.28389162
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.22718191
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.14612520
13TAF15_26573619_Chip-Seq_HEK293_Human2.13734073
14VDR_22108803_ChIP-Seq_LS180_Human2.13674384
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.11893482
16ZFP57_27257070_Chip-Seq_ESCs_Mouse2.07499147
17NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.03985081
18GBX2_23144817_ChIP-Seq_PC3_Human2.02016484
19EST1_17652178_ChIP-ChIP_JURKAT_Human1.95404063
20CTBP2_25329375_ChIP-Seq_LNCAP_Human1.91661002
21E2F4_17652178_ChIP-ChIP_JURKAT_Human1.89837859
22ELK1_19687146_ChIP-ChIP_HELA_Human1.88730420
23MYC_18940864_ChIP-ChIP_HL60_Human1.77658570
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.77035432
25P300_19829295_ChIP-Seq_ESCs_Human1.75932052
26IRF1_19129219_ChIP-ChIP_H3396_Human1.72836956
27KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.71350905
28CTBP1_25329375_ChIP-Seq_LNCAP_Human1.70449869
29RNF2_27304074_Chip-Seq_NSC_Mouse1.67370870
30CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.66866562
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65590716
32POU5F1_16153702_ChIP-ChIP_HESCs_Human1.65058132
33E2F7_22180533_ChIP-Seq_HELA_Human1.64812014
34HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.58450044
35CREB1_15753290_ChIP-ChIP_HEK293T_Human1.53876311
36MYC_18555785_ChIP-Seq_MESCs_Mouse1.52230045
37TP63_19390658_ChIP-ChIP_HaCaT_Human1.43623217
38TOP2B_26459242_ChIP-Seq_MCF-7_Human1.42631524
39CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.40772995
40PADI4_21655091_ChIP-ChIP_MCF-7_Human1.40603625
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40273300
42ETS1_20019798_ChIP-Seq_JURKAT_Human1.39598376
43HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.37756212
44MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.36514092
45VDR_23849224_ChIP-Seq_CD4+_Human1.35614725
46CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.35045461
47CBX2_27304074_Chip-Seq_ESCs_Mouse1.34878512
48SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.34732854
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34042195
50BMI1_23680149_ChIP-Seq_NPCS_Mouse1.29671999
51JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.29369846
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.29248567
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.29237005
54MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26651762
55PIAS1_25552417_ChIP-Seq_VCAP_Human1.24647215
56SOX2_16153702_ChIP-ChIP_HESCs_Human1.24437904
57MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.24376865
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.24136831
59CBP_20019798_ChIP-Seq_JUKART_Human1.23222092
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23222092
61FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.22283416
62KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.21687019
63KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.21687019
64KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.21687019
65AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.20760349
66SMAD4_21799915_ChIP-Seq_A2780_Human1.20515618
67FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.17970049
68SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.17285794
69FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.16938350
70STAT3_23295773_ChIP-Seq_U87_Human1.14969435
71NANOG_16153702_ChIP-ChIP_HESCs_Human1.14730558
72SMAD3_21741376_ChIP-Seq_EPCs_Human1.13323125
73SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.12191926
74KLF5_20875108_ChIP-Seq_MESCs_Mouse1.11632779
75RUNX2_22187159_ChIP-Seq_PCA_Human1.08582466
76WT1_19549856_ChIP-ChIP_CCG9911_Human1.08247279
77ER_23166858_ChIP-Seq_MCF-7_Human1.08086599
78NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.06440186
79RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.06122661
80JUN_21703547_ChIP-Seq_K562_Human1.05821332
81OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05127510
82TTF2_22483619_ChIP-Seq_HELA_Human1.04053553
83SOX9_26525672_Chip-Seq_HEART_Mouse1.03183342
84THAP11_20581084_ChIP-Seq_MESCs_Mouse1.02849521
85PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.02188421
86FOXM1_23109430_ChIP-Seq_U2OS_Human0.98816347
87AR_25329375_ChIP-Seq_VCAP_Human0.98801470
88FOXP3_21729870_ChIP-Seq_TREG_Human0.97084843
89TCF4_23295773_ChIP-Seq_U87_Human0.95678036
90EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.94667568
91GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.94148120
92HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.93761838
93PCGF2_27294783_Chip-Seq_ESCs_Mouse0.93090420
94TP53_22573176_ChIP-Seq_HFKS_Human0.92422819
95GABP_19822575_ChIP-Seq_HepG2_Human0.92195726
96TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.92045183
97GATA1_26923725_Chip-Seq_HPCs_Mouse0.91289718
98TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90216626
99POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.90216626
100MYC_19030024_ChIP-ChIP_MESCs_Mouse0.89557352

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern2.86566722
2MP0008877_abnormal_DNA_methylation2.76528846
3MP0008058_abnormal_DNA_repair2.73332716
4MP0000566_synostosis2.58597737
5MP0003136_yellow_coat_color2.39926407
6MP0010094_abnormal_chromosome_stability2.32498281
7MP0001529_abnormal_vocalization2.19795564
8MP0006292_abnormal_olfactory_placode2.18550235
9MP0004133_heterotaxia2.12164010
10MP0003122_maternal_imprinting1.98787326
11MP0003693_abnormal_embryo_hatching1.95155779
12MP0000778_abnormal_nervous_system1.94322831
13MP0001293_anophthalmia1.85336653
14MP0002102_abnormal_ear_morphology1.84541788
15MP0006276_abnormal_autonomic_nervous1.82737312
16MP0003718_maternal_effect1.77833400
17MP0003937_abnormal_limbs/digits/tail_de1.71325786
18MP0002938_white_spotting1.67257983
19MP0003890_abnormal_embryonic-extraembry1.58223815
20MP0004147_increased_porphyrin_level1.57416861
21MP0003121_genomic_imprinting1.54351384
22MP0006072_abnormal_retinal_apoptosis1.53954285
23MP0008932_abnormal_embryonic_tissue1.43592801
24MP0000631_abnormal_neuroendocrine_gland1.43513977
25MP0005253_abnormal_eye_physiology1.39261511
26MP0002653_abnormal_ependyma_morphology1.38797713
27MP0003567_abnormal_fetal_cardiomyocyte1.37655429
28MP0008995_early_reproductive_senescence1.37157423
29MP0008789_abnormal_olfactory_epithelium1.37062998
30MP0000647_abnormal_sebaceous_gland1.37052898
31MP0002233_abnormal_nose_morphology1.34657679
32MP0001984_abnormal_olfaction1.34305697
33MP0002210_abnormal_sex_determination1.33966542
34MP0004859_abnormal_synaptic_plasticity1.33734087
35MP0009046_muscle_twitch1.33341076
36MP0003698_abnormal_male_reproductive1.30167891
37MP0005551_abnormal_eye_electrophysiolog1.29313242
38MP0000383_abnormal_hair_follicle1.28222664
39MP0004742_abnormal_vestibular_system1.28207149
40MP0001188_hyperpigmentation1.27257816
41MP0004957_abnormal_blastocyst_morpholog1.26408224
42MP0001929_abnormal_gametogenesis1.26025699
43MP0002736_abnormal_nociception_after1.23365667
44MP0003077_abnormal_cell_cycle1.23039657
45MP0003861_abnormal_nervous_system1.20342205
46MP0003635_abnormal_synaptic_transmissio1.17515543
47MP0002184_abnormal_innervation1.16646566
48MP0000049_abnormal_middle_ear1.15869154
49MP0001486_abnormal_startle_reflex1.14292696
50MP0003119_abnormal_digestive_system1.14074601
51MP0009745_abnormal_behavioral_response1.13273501
52MP0002751_abnormal_autonomic_nervous1.12894548
53MP0008007_abnormal_cellular_replicative1.12499765
54MP0002572_abnormal_emotion/affect_behav1.11320341
55MP0002272_abnormal_nervous_system1.10958645
56MP0002067_abnormal_sensory_capabilities1.10255343
57MP0000653_abnormal_sex_gland1.09255754
58MP0001145_abnormal_male_reproductive1.08224628
59MP0001286_abnormal_eye_development1.07205396
60MP0010030_abnormal_orbit_morphology1.06758633
61MP0005394_taste/olfaction_phenotype1.06360958
62MP0005499_abnormal_olfactory_system1.06360958
63MP0000955_abnormal_spinal_cord1.06202563
64MP0002752_abnormal_somatic_nervous1.06062815
65MP0005187_abnormal_penis_morphology1.05903371
66MP0005391_vision/eye_phenotype1.04660972
67MP0002234_abnormal_pharynx_morphology1.04276357
68MP0002084_abnormal_developmental_patter1.02195404
69MP0003787_abnormal_imprinting1.01967611
70MP0001968_abnormal_touch/_nociception1.01169850
71MP0002063_abnormal_learning/memory/cond1.00890031
72MP0004270_analgesia0.98455358
73MP0003111_abnormal_nucleus_morphology0.98236694
74MP0002152_abnormal_brain_morphology0.95527780
75MP0000427_abnormal_hair_cycle0.95506020
76MP0002249_abnormal_larynx_morphology0.95414551
77MP0002557_abnormal_social/conspecific_i0.93428167
78MP0002882_abnormal_neuron_morphology0.91735939
79MP0001299_abnormal_eye_distance/0.90964009
80MP0000372_irregular_coat_pigmentation0.90598210
81MP0002734_abnormal_mechanical_nocicepti0.88974840
82MP0000026_abnormal_inner_ear0.87939792
83MP0002132_abnormal_respiratory_system0.87712198
84MP0005171_absent_coat_pigmentation0.87327015
85MP0001485_abnormal_pinna_reflex0.87242170
86MP0003755_abnormal_palate_morphology0.86815388
87MP0002085_abnormal_embryonic_tissue0.86643253
88MP0003786_premature_aging0.85953179
89MP0008057_abnormal_DNA_replication0.84814299
90MP0005195_abnormal_posterior_eye0.84441498
91MP0002160_abnormal_reproductive_system0.84140549
92MP0002638_abnormal_pupillary_reflex0.83243216
93MP0003938_abnormal_ear_development0.83033960
94MP0004811_abnormal_neuron_physiology0.82195246
95MP0002095_abnormal_skin_pigmentation0.81840867
96MP0004142_abnormal_muscle_tone0.80546161
97MP0002161_abnormal_fertility/fecundity0.80392541
98MP0009697_abnormal_copulation0.80336904
99MP0009703_decreased_birth_body0.79735188
100MP0004924_abnormal_behavior0.79627610

Predicted human phenotypes

RankGene SetZ-score
1True hermaphroditism (HP:0010459)3.59649321
2Pancreatic fibrosis (HP:0100732)3.50551089
3Gait imbalance (HP:0002141)3.43629672
4Abnormality of midbrain morphology (HP:0002418)3.41801836
5Molar tooth sign on MRI (HP:0002419)3.41801836
6Chronic hepatic failure (HP:0100626)3.25128422
7Cortical dysplasia (HP:0002539)3.20186580
8Congenital primary aphakia (HP:0007707)3.17465416
9Medial flaring of the eyebrow (HP:0010747)3.08915641
10Abnormality of the labia minora (HP:0012880)3.06594187
11Pancreatic cysts (HP:0001737)2.98488213
12Nephronophthisis (HP:0000090)2.93931466
13Nephrogenic diabetes insipidus (HP:0009806)2.77318182
14Supernumerary spleens (HP:0009799)2.74537127
15Genital tract atresia (HP:0001827)2.74023723
16Dynein arm defect of respiratory motile cilia (HP:0012255)2.65244379
17Absent/shortened dynein arms (HP:0200106)2.65244379
18Vaginal atresia (HP:0000148)2.64321115
19Hyperglycinemia (HP:0002154)2.64121047
20Abnormal respiratory motile cilium morphology (HP:0005938)2.55916069
21Abnormal respiratory epithelium morphology (HP:0012253)2.55916069
22Poor coordination (HP:0002370)2.54225551
23Postaxial foot polydactyly (HP:0001830)2.50521958
24Abnormal ciliary motility (HP:0012262)2.46786001
25Abnormality of the renal medulla (HP:0100957)2.37864280
26Bifid tongue (HP:0010297)2.35850557
27Abnormal respiratory motile cilium physiology (HP:0012261)2.34437936
28Hyperglycinuria (HP:0003108)2.30492502
29Preaxial hand polydactyly (HP:0001177)2.30055500
30B lymphocytopenia (HP:0010976)2.27019663
31Aplasia/Hypoplasia of the tongue (HP:0010295)2.24021123
32Retinal dysplasia (HP:0007973)2.23119814
33Broad foot (HP:0001769)2.22834877
34Occipital encephalocele (HP:0002085)2.21059474
35Hypoplasia of the thymus (HP:0000778)2.19323900
36Sclerocornea (HP:0000647)2.18553930
37Drooling (HP:0002307)2.17106092
38Postaxial hand polydactyly (HP:0001162)2.15964712
39Colon cancer (HP:0003003)2.15355543
40Abnormality of glycine metabolism (HP:0010895)2.11500842
41Abnormality of serine family amino acid metabolism (HP:0010894)2.11500842
42Anencephaly (HP:0002323)2.11146298
43Aplasia/Hypoplasia of the tibia (HP:0005772)2.05178829
44Specific learning disability (HP:0001328)2.01151204
45Abnormality of B cell number (HP:0010975)1.99997047
46Median cleft lip (HP:0000161)1.98394178
47Polyphagia (HP:0002591)1.97388973
48Decreased central vision (HP:0007663)1.97388368
49Short tibia (HP:0005736)1.97231008
50Abnormal biliary tract physiology (HP:0012439)1.95317021
51Bile duct proliferation (HP:0001408)1.95317021
52Abnormal lung lobation (HP:0002101)1.94529157
53Tubulointerstitial nephritis (HP:0001970)1.93958496
54Type II lissencephaly (HP:0007260)1.92122808
55Volvulus (HP:0002580)1.91327103
56Oculomotor apraxia (HP:0000657)1.90640313
57Excessive salivation (HP:0003781)1.87437805
58Methylmalonic acidemia (HP:0002912)1.86802187
59Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.86618987
60Hyperventilation (HP:0002883)1.86204469
61Cystic liver disease (HP:0006706)1.85896127
62Erythroderma (HP:0001019)1.83062510
63Amyotrophic lateral sclerosis (HP:0007354)1.81640728
64Septo-optic dysplasia (HP:0100842)1.80758394
65Abnormality of macular pigmentation (HP:0008002)1.80689241
66Abnormality of serum amino acid levels (HP:0003112)1.80466112
67Severe combined immunodeficiency (HP:0004430)1.79929918
68Optic nerve hypoplasia (HP:0000609)1.79586522
69Anophthalmia (HP:0000528)1.79434651
70Optic nerve coloboma (HP:0000588)1.77846859
71Progressive cerebellar ataxia (HP:0002073)1.77524845
72Atrophy/Degeneration involving motor neurons (HP:0007373)1.77504119
73Dandy-Walker malformation (HP:0001305)1.75865646
74Oligodactyly (hands) (HP:0001180)1.73238460
75Prominent nasal bridge (HP:0000426)1.72507140
76Multicystic kidney dysplasia (HP:0000003)1.72298635
77Aganglionic megacolon (HP:0002251)1.72007945
78Abnormality of alanine metabolism (HP:0010916)1.70395929
79Hyperalaninemia (HP:0003348)1.70395929
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.70395929
81Aplasia/Hypoplasia of the uvula (HP:0010293)1.70319665
82Astigmatism (HP:0000483)1.70030206
83Thyroiditis (HP:0100646)1.67742623
84Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67700934
85Birth length less than 3rd percentile (HP:0003561)1.66875198
86Neuroendocrine neoplasm (HP:0100634)1.66371315
87Methylmalonic aciduria (HP:0012120)1.66177866
88Micropenis (HP:0000054)1.64591282
89Gonadotropin excess (HP:0000837)1.64155816
90Lissencephaly (HP:0001339)1.63992020
91Broad-based gait (HP:0002136)1.62943833
92Absent rod-and cone-mediated responses on ERG (HP:0007688)1.62794866
93Cutaneous finger syndactyly (HP:0010554)1.62659886
94Meckel diverticulum (HP:0002245)1.62611737
95Narrow forehead (HP:0000341)1.62147136
96Partial agenesis of the corpus callosum (HP:0001338)1.61985631
97Male pseudohermaphroditism (HP:0000037)1.61455561
98Pendular nystagmus (HP:0012043)1.60765171
99Aplasia/Hypoplasia of the spleen (HP:0010451)1.60717956
100Sloping forehead (HP:0000340)1.60097603

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK3.78901650
2WNK33.43525686
3MAP3K42.71319992
4MARK12.64568340
5CDK192.41378868
6PNCK2.40804993
7MAP2K72.23611146
8BCR2.16516454
9SRPK12.15212226
10TSSK62.12492196
11DYRK22.11668309
12EIF2AK31.86968300
13TNIK1.85600315
14EPHA41.82279436
15TRIM281.78297759
16MKNK21.73333898
17NEK11.71943132
18PLK31.68479473
19NUAK11.67827271
20TTK1.67721067
21FRK1.61080678
22CDC71.58908304
23MKNK11.58220502
24PBK1.55411534
25MAPK131.53248312
26ZAK1.52750661
27STK161.48030541
28BMPR1B1.47413697
29RPS6KA41.37375932
30PLK41.35908081
31BUB11.33326015
32PINK11.32190228
33NTRK21.28578379
34DYRK31.26704302
35VRK11.26275795
36BRSK21.25496977
37WEE11.24657944
38PLK21.20088975
39VRK21.17641982
40PLK11.17400649
41BCKDK1.13132046
42ERBB31.12127067
43MAP4K21.09863947
44ADRBK21.08220313
45CSNK1G21.05592696
46NEK21.02720615
47CSNK1A1L1.01694879
48MET0.97888541
49CHEK20.97265337
50TAF10.96256451
51ATR0.96051604
52CSNK1G30.96000427
53CSNK1G10.95662713
54STK38L0.93229365
55MAPK150.89734383
56MAP2K40.87445458
57DYRK1A0.83405098
58NTRK30.81788123
59EIF2AK10.74188061
60MAP3K100.72396137
61LATS10.72322805
62ATM0.71402764
63PKN10.70825685
64MINK10.68788728
65MAP3K120.68336431
66OXSR10.68315296
67PRKCE0.63707216
68INSRR0.63036392
69EIF2AK20.62808100
70PRKCG0.61969956
71PHKG10.61582632
72PHKG20.61582632
73BRSK10.59424177
74KSR10.59025256
75PAK30.57608139
76CDK30.56638582
77FLT30.54716267
78GRK10.54430955
79CSNK1E0.51430619
80BRD40.49187420
81TGFBR10.47756317
82CAMK1G0.45794371
83CAMK2A0.45594353
84PRKD30.45591120
85DYRK1B0.43379292
86PRKDC0.41888559
87UHMK10.41452626
88CDK10.40410554
89CHEK10.40026086
90FGFR20.39302405
91AURKB0.38605225
92AURKA0.38569551
93WNK40.38501588
94NTRK10.37359264
95CDK20.36197857
96RPS6KB10.35815410
97NME10.34418861
98SIK20.31572856
99FGFR10.31041966
100STK30.29451731

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.08084174
2Non-homologous end-joining_Homo sapiens_hsa034502.97324313
3Propanoate metabolism_Homo sapiens_hsa006402.74566550
4Steroid biosynthesis_Homo sapiens_hsa001002.58153211
5Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.51920291
6Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.44432423
7Basal transcription factors_Homo sapiens_hsa030222.36675588
8Mismatch repair_Homo sapiens_hsa034302.31453985
9Nicotine addiction_Homo sapiens_hsa050332.10626043
10Fanconi anemia pathway_Homo sapiens_hsa034602.05281562
11Homologous recombination_Homo sapiens_hsa034402.03897916
12RNA transport_Homo sapiens_hsa030132.03681931
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.02461899
14Protein export_Homo sapiens_hsa030602.02281694
15Butanoate metabolism_Homo sapiens_hsa006501.96937394
16Nucleotide excision repair_Homo sapiens_hsa034201.91234876
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.85947486
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.85808643
19RNA degradation_Homo sapiens_hsa030181.71782438
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.68798655
21Proteasome_Homo sapiens_hsa030501.67830429
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.60493415
23DNA replication_Homo sapiens_hsa030301.58841499
24Base excision repair_Homo sapiens_hsa034101.54211439
25RNA polymerase_Homo sapiens_hsa030201.52600239
26Spliceosome_Homo sapiens_hsa030401.51829807
27Phototransduction_Homo sapiens_hsa047441.40415523
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.37965435
29Cysteine and methionine metabolism_Homo sapiens_hsa002701.33975909
30Cell cycle_Homo sapiens_hsa041101.32231967
31One carbon pool by folate_Homo sapiens_hsa006701.32136322
32mRNA surveillance pathway_Homo sapiens_hsa030151.29272635
33Parkinsons disease_Homo sapiens_hsa050121.28519015
34Selenocompound metabolism_Homo sapiens_hsa004501.26161056
35Oxidative phosphorylation_Homo sapiens_hsa001901.24500182
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.23214211
37Pyruvate metabolism_Homo sapiens_hsa006201.17187253
38Huntingtons disease_Homo sapiens_hsa050161.16634167
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.16005696
40Fatty acid elongation_Homo sapiens_hsa000621.12831405
41beta-Alanine metabolism_Homo sapiens_hsa004101.11942944
42Oocyte meiosis_Homo sapiens_hsa041141.09138411
43Taste transduction_Homo sapiens_hsa047421.04121979
44Fatty acid metabolism_Homo sapiens_hsa012121.01806327
45Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.99672557
46Olfactory transduction_Homo sapiens_hsa047400.96845357
47Purine metabolism_Homo sapiens_hsa002300.96241462
48Biosynthesis of amino acids_Homo sapiens_hsa012300.92586781
49Basal cell carcinoma_Homo sapiens_hsa052170.91050005
50Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88803357
51Hedgehog signaling pathway_Homo sapiens_hsa043400.85694522
52GABAergic synapse_Homo sapiens_hsa047270.85650318
53Hippo signaling pathway_Homo sapiens_hsa043900.85427072
54Pyrimidine metabolism_Homo sapiens_hsa002400.84180387
55Carbon metabolism_Homo sapiens_hsa012000.83690295
56Peroxisome_Homo sapiens_hsa041460.77009979
57Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.76603331
58Primary bile acid biosynthesis_Homo sapiens_hsa001200.76205674
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73022126
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.72744794
61Lysine degradation_Homo sapiens_hsa003100.70350911
62Axon guidance_Homo sapiens_hsa043600.69946618
63Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.68234048
64Arginine and proline metabolism_Homo sapiens_hsa003300.68031376
65Morphine addiction_Homo sapiens_hsa050320.67220630
66Alzheimers disease_Homo sapiens_hsa050100.67001513
67Regulation of autophagy_Homo sapiens_hsa041400.65616291
68Metabolic pathways_Homo sapiens_hsa011000.65459297
69Glutathione metabolism_Homo sapiens_hsa004800.62582052
70p53 signaling pathway_Homo sapiens_hsa041150.61383688
71Cardiac muscle contraction_Homo sapiens_hsa042600.60208629
72Wnt signaling pathway_Homo sapiens_hsa043100.60022104
73Fatty acid degradation_Homo sapiens_hsa000710.59227397
74Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.58082001
75Glutamatergic synapse_Homo sapiens_hsa047240.57917954
76Ribosome_Homo sapiens_hsa030100.57241765
77Ether lipid metabolism_Homo sapiens_hsa005650.56377821
78Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55633741
79Circadian rhythm_Homo sapiens_hsa047100.54899783
80Dopaminergic synapse_Homo sapiens_hsa047280.54292907
81Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.52480254
822-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.52233879
83Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.50605928
84Linoleic acid metabolism_Homo sapiens_hsa005910.49097965
85N-Glycan biosynthesis_Homo sapiens_hsa005100.48305295
86Folate biosynthesis_Homo sapiens_hsa007900.45191929
87TGF-beta signaling pathway_Homo sapiens_hsa043500.44624452
88Nitrogen metabolism_Homo sapiens_hsa009100.43933006
89Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43498128
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42717021
91Caffeine metabolism_Homo sapiens_hsa002320.42465760
92Circadian entrainment_Homo sapiens_hsa047130.42268298
93Cocaine addiction_Homo sapiens_hsa050300.41872854
94Synaptic vesicle cycle_Homo sapiens_hsa047210.41743721
95Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39940164
96Amphetamine addiction_Homo sapiens_hsa050310.37033694
97Cyanoamino acid metabolism_Homo sapiens_hsa004600.36914443
98Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.36702196
99Tryptophan metabolism_Homo sapiens_hsa003800.36282180
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.32243195

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »