

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neuronal stem cell maintenance (GO:0097150) | 7.00144313 |
| 2 | nephron tubule morphogenesis (GO:0072078) | 6.93736744 |
| 3 | nephron epithelium morphogenesis (GO:0072088) | 6.93736744 |
| 4 | protein localization to cilium (GO:0061512) | 6.57714718 |
| 5 | forebrain neuron differentiation (GO:0021879) | 5.59037440 |
| 6 | glomerular filtration (GO:0003094) | 5.55818426 |
| 7 | regulation of timing of cell differentiation (GO:0048505) | 5.17295480 |
| 8 | renal tubule morphogenesis (GO:0061333) | 5.05754088 |
| 9 | neuron fate determination (GO:0048664) | 5.01374943 |
| 10 | renal filtration (GO:0097205) | 4.89123259 |
| 11 | regulation of development, heterochronic (GO:0040034) | 4.73794448 |
| 12 | glomerular basement membrane development (GO:0032836) | 4.70877436 |
| 13 | behavioral response to nicotine (GO:0035095) | 4.69759045 |
| 14 | negative regulation of epidermal cell differentiation (GO:0045605) | 4.68284744 |
| 15 | spermatid nucleus differentiation (GO:0007289) | 4.64708071 |
| 16 | positive regulation of Notch signaling pathway (GO:0045747) | 4.59237488 |
| 17 | negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) | 4.54148183 |
| 18 | adaptation of signaling pathway (GO:0023058) | 4.39654723 |
| 19 | cardiac right ventricle morphogenesis (GO:0003215) | 4.08502490 |
| 20 | dermatan sulfate biosynthetic process (GO:0030208) | 4.05163266 |
| 21 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 4.04960621 |
| 22 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 4.01534814 |
| 23 | neuron cell-cell adhesion (GO:0007158) | 3.94209983 |
| 24 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 3.92495482 |
| 25 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.91441856 |
| 26 | neural tube formation (GO:0001841) | 3.81621066 |
| 27 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 3.74431126 |
| 28 | negative regulation of mast cell activation (GO:0033004) | 3.66882634 |
| 29 | acrosome assembly (GO:0001675) | 3.60778972 |
| 30 | protein polyglutamylation (GO:0018095) | 3.59008839 |
| 31 | nonmotile primary cilium assembly (GO:0035058) | 3.58779346 |
| 32 | dermatan sulfate metabolic process (GO:0030205) | 3.56688239 |
| 33 | DNA damage response, detection of DNA damage (GO:0042769) | 3.55919266 |
| 34 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 3.48783504 |
| 35 | cerebral cortex neuron differentiation (GO:0021895) | 3.46223029 |
| 36 | intraciliary transport (GO:0042073) | 3.45882009 |
| 37 | regulation of action potential (GO:0098900) | 3.45299866 |
| 38 | glycosphingolipid biosynthetic process (GO:0006688) | 3.40335915 |
| 39 | negative regulation of epidermis development (GO:0045683) | 3.39372922 |
| 40 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.38723185 |
| 41 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.38723185 |
| 42 | kidney morphogenesis (GO:0060993) | 3.37636485 |
| 43 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 3.33990269 |
| 44 | retinal ganglion cell axon guidance (GO:0031290) | 3.28524933 |
| 45 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 3.26468547 |
| 46 | tongue development (GO:0043586) | 3.24110330 |
| 47 | cilium morphogenesis (GO:0060271) | 3.18080488 |
| 48 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.13454501 |
| 49 | axonal fasciculation (GO:0007413) | 3.11156895 |
| 50 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.10952831 |
| 51 | fucose catabolic process (GO:0019317) | 3.06363392 |
| 52 | L-fucose metabolic process (GO:0042354) | 3.06363392 |
| 53 | L-fucose catabolic process (GO:0042355) | 3.06363392 |
| 54 | regulation of organ formation (GO:0003156) | 3.06292636 |
| 55 | limb bud formation (GO:0060174) | 3.04408684 |
| 56 | tryptophan catabolic process (GO:0006569) | 3.04245053 |
| 57 | indole-containing compound catabolic process (GO:0042436) | 3.04245053 |
| 58 | indolalkylamine catabolic process (GO:0046218) | 3.04245053 |
| 59 | radial glial cell differentiation (GO:0060019) | 3.04131977 |
| 60 | kynurenine metabolic process (GO:0070189) | 3.00779301 |
| 61 | neuronal action potential (GO:0019228) | 2.99781983 |
| 62 | regulation of hexokinase activity (GO:1903299) | 2.98092170 |
| 63 | regulation of glucokinase activity (GO:0033131) | 2.98092170 |
| 64 | negative regulation of glial cell proliferation (GO:0060253) | 2.96735666 |
| 65 | regulation of oligodendrocyte differentiation (GO:0048713) | 2.95766831 |
| 66 | synaptic transmission, cholinergic (GO:0007271) | 2.95620195 |
| 67 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 2.95248220 |
| 68 | regulation of cardioblast proliferation (GO:0003264) | 2.95248220 |
| 69 | innervation (GO:0060384) | 2.94713369 |
| 70 | axon ensheathment in central nervous system (GO:0032291) | 2.87853388 |
| 71 | central nervous system myelination (GO:0022010) | 2.87853388 |
| 72 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.87327344 |
| 73 | axoneme assembly (GO:0035082) | 2.86992010 |
| 74 | relaxation of smooth muscle (GO:0044557) | 2.86269641 |
| 75 | negative regulation of cell cycle arrest (GO:0071157) | 2.84534164 |
| 76 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 2.83830724 |
| 77 | positive regulation of mast cell degranulation (GO:0043306) | 2.83830724 |
| 78 | regulation of gene silencing by RNA (GO:0060966) | 2.83666394 |
| 79 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.83666394 |
| 80 | regulation of gene silencing by miRNA (GO:0060964) | 2.83666394 |
| 81 | ventricular system development (GO:0021591) | 2.83538438 |
| 82 | negative regulation of glial cell differentiation (GO:0045686) | 2.83416810 |
| 83 | metallo-sulfur cluster assembly (GO:0031163) | 2.82839260 |
| 84 | iron-sulfur cluster assembly (GO:0016226) | 2.82839260 |
| 85 | protein localization to synapse (GO:0035418) | 2.80018946 |
| 86 | presynaptic membrane assembly (GO:0097105) | 2.79306478 |
| 87 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.78079796 |
| 88 | short-term memory (GO:0007614) | 2.77543736 |
| 89 | platelet dense granule organization (GO:0060155) | 2.75373142 |
| 90 | ganglioside metabolic process (GO:0001573) | 2.74535653 |
| 91 | renal absorption (GO:0070293) | 2.74484376 |
| 92 | neuron recognition (GO:0008038) | 2.73423661 |
| 93 | cell-cell signaling involved in cell fate commitment (GO:0045168) | 2.72589183 |
| 94 | regulation of Notch signaling pathway (GO:0008593) | 2.72097661 |
| 95 | telencephalon development (GO:0021537) | 2.71220604 |
| 96 | epithelial cilium movement (GO:0003351) | 2.69064486 |
| 97 | positive regulation of glial cell differentiation (GO:0045687) | 2.68094876 |
| 98 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.67613510 |
| 99 | piRNA metabolic process (GO:0034587) | 2.67255921 |
| 100 | sympathetic nervous system development (GO:0048485) | 2.66815210 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.76539712 |
| 2 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.75237311 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.73098521 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.30463566 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.24561427 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.01499477 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.86871498 |
| 8 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.71327850 |
| 9 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.38134468 |
| 10 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.32290484 |
| 11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.27355083 |
| 12 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.23833677 |
| 13 | EWS_26573619_Chip-Seq_HEK293_Human | 2.15764111 |
| 14 | RNF2_27304074_Chip-Seq_NSC_Mouse | 2.13920636 |
| 15 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.12389500 |
| 16 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.11417912 |
| 17 | P300_19829295_ChIP-Seq_ESCs_Human | 2.04501007 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.04269855 |
| 19 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.03457465 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 1.98756787 |
| 21 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.98287735 |
| 22 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.94553608 |
| 23 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.89569818 |
| 24 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.89569818 |
| 25 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.89409646 |
| 26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.89146399 |
| 27 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.88332951 |
| 28 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.81506584 |
| 29 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.73214686 |
| 30 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.71482789 |
| 31 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.69674414 |
| 32 | AR_25329375_ChIP-Seq_VCAP_Human | 1.69268568 |
| 33 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.68590806 |
| 34 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.65017526 |
| 35 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.62373852 |
| 36 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.59851213 |
| 37 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.54946787 |
| 38 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.54114820 |
| 39 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.52528959 |
| 40 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.49627278 |
| 41 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.49292385 |
| 42 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.49069238 |
| 43 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.48044976 |
| 44 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.47955542 |
| 45 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.47744774 |
| 46 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.47744774 |
| 47 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.47202562 |
| 48 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.46925146 |
| 49 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.46919890 |
| 50 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.46198031 |
| 51 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.44601933 |
| 52 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.42683103 |
| 53 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.41496995 |
| 54 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.41416343 |
| 55 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.40094471 |
| 56 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.39037109 |
| 57 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.37997956 |
| 58 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.37270457 |
| 59 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 1.36937077 |
| 60 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.36593302 |
| 61 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.36593302 |
| 62 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.35688142 |
| 63 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.35688142 |
| 64 | STAT3_23295773_ChIP-Seq_U87_Human | 1.35182294 |
| 65 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.34464100 |
| 66 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.30852722 |
| 67 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.29812909 |
| 68 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.27735031 |
| 69 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.25413813 |
| 70 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.24837372 |
| 71 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.24831307 |
| 72 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.23897448 |
| 73 | TCF4_23295773_ChIP-Seq_U87_Human | 1.22073867 |
| 74 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.21747441 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21253976 |
| 76 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.20207999 |
| 77 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17172545 |
| 78 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.17101544 |
| 79 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16665689 |
| 80 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.15669839 |
| 81 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.12697848 |
| 82 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.12627464 |
| 83 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.11224582 |
| 84 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.10402271 |
| 85 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.08734263 |
| 86 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.08633042 |
| 87 | KDM2B_26808549_Chip-Seq_REH_Human | 1.07997653 |
| 88 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.06321078 |
| 89 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.04293960 |
| 90 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.04234932 |
| 91 | JUN_21703547_ChIP-Seq_K562_Human | 1.04182533 |
| 92 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.03927742 |
| 93 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.03029043 |
| 94 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.02288083 |
| 95 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.02247883 |
| 96 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.01786360 |
| 97 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.00091904 |
| 98 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.99916696 |
| 99 | RXR_22108803_ChIP-Seq_LS180_Human | 0.99556901 |
| 100 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.99416001 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003136_yellow_coat_color | 4.37313918 |
| 2 | MP0002653_abnormal_ependyma_morphology | 3.45651974 |
| 3 | MP0002102_abnormal_ear_morphology | 3.20233175 |
| 4 | MP0008789_abnormal_olfactory_epithelium | 3.15144411 |
| 5 | MP0003880_abnormal_central_pattern | 3.12478007 |
| 6 | MP0004133_heterotaxia | 2.79455001 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.66279758 |
| 8 | MP0005499_abnormal_olfactory_system | 2.61978764 |
| 9 | MP0005394_taste/olfaction_phenotype | 2.61978764 |
| 10 | MP0008995_early_reproductive_senescence | 2.56731374 |
| 11 | MP0002822_catalepsy | 2.54390363 |
| 12 | MP0003195_calcinosis | 2.45372268 |
| 13 | MP0002751_abnormal_autonomic_nervous | 2.29286551 |
| 14 | MP0000467_abnormal_esophagus_morphology | 2.28667162 |
| 15 | MP0000569_abnormal_digit_pigmentation | 2.22026843 |
| 16 | MP0006292_abnormal_olfactory_placode | 2.20254133 |
| 17 | MP0001984_abnormal_olfaction | 2.18570229 |
| 18 | MP0002928_abnormal_bile_duct | 2.18434857 |
| 19 | MP0004742_abnormal_vestibular_system | 1.99813394 |
| 20 | MP0002234_abnormal_pharynx_morphology | 1.94913214 |
| 21 | MP0000631_abnormal_neuroendocrine_gland | 1.86739675 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 1.86204131 |
| 23 | MP0003890_abnormal_embryonic-extraembry | 1.82673094 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.76698445 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 1.76678134 |
| 26 | MP0002736_abnormal_nociception_after | 1.71173466 |
| 27 | MP0009053_abnormal_anal_canal | 1.70042245 |
| 28 | MP0003011_delayed_dark_adaptation | 1.68728837 |
| 29 | MP0003646_muscle_fatigue | 1.67168687 |
| 30 | MP0003122_maternal_imprinting | 1.66930070 |
| 31 | MP0008961_abnormal_basal_metabolism | 1.65086450 |
| 32 | MP0002272_abnormal_nervous_system | 1.63979595 |
| 33 | MP0008875_abnormal_xenobiotic_pharmacok | 1.54272908 |
| 34 | MP0001485_abnormal_pinna_reflex | 1.54045387 |
| 35 | MP0000778_abnormal_nervous_system | 1.53464594 |
| 36 | MP0005423_abnormal_somatic_nervous | 1.53006312 |
| 37 | MP0001293_anophthalmia | 1.50590081 |
| 38 | MP0006276_abnormal_autonomic_nervous | 1.46356212 |
| 39 | MP0000026_abnormal_inner_ear | 1.43278457 |
| 40 | MP0000383_abnormal_hair_follicle | 1.42727656 |
| 41 | MP0002876_abnormal_thyroid_physiology | 1.42641511 |
| 42 | MP0004043_abnormal_pH_regulation | 1.42420843 |
| 43 | MP0005195_abnormal_posterior_eye | 1.41552966 |
| 44 | MP0009379_abnormal_foot_pigmentation | 1.40167686 |
| 45 | MP0005646_abnormal_pituitary_gland | 1.37325929 |
| 46 | MP0000955_abnormal_spinal_cord | 1.33132453 |
| 47 | MP0002282_abnormal_trachea_morphology | 1.32908349 |
| 48 | MP0005253_abnormal_eye_physiology | 1.32745012 |
| 49 | MP0001286_abnormal_eye_development | 1.30831685 |
| 50 | MP0002734_abnormal_mechanical_nocicepti | 1.29879413 |
| 51 | MP0000372_irregular_coat_pigmentation | 1.29070137 |
| 52 | MP0001970_abnormal_pain_threshold | 1.28442200 |
| 53 | MP0009046_muscle_twitch | 1.25847109 |
| 54 | MP0009745_abnormal_behavioral_response | 1.25827929 |
| 55 | MP0002064_seizures | 1.24971921 |
| 56 | MP0002752_abnormal_somatic_nervous | 1.18850267 |
| 57 | MP0004142_abnormal_muscle_tone | 1.17460330 |
| 58 | MP0003119_abnormal_digestive_system | 1.16350974 |
| 59 | MP0004147_increased_porphyrin_level | 1.12890598 |
| 60 | MP0000534_abnormal_ureter_morphology | 1.10452821 |
| 61 | MP0002733_abnormal_thermal_nociception | 1.09278263 |
| 62 | MP0005645_abnormal_hypothalamus_physiol | 1.04962587 |
| 63 | MP0002277_abnormal_respiratory_mucosa | 1.02952875 |
| 64 | MP0003635_abnormal_synaptic_transmissio | 1.02139055 |
| 65 | MP0002638_abnormal_pupillary_reflex | 1.01214296 |
| 66 | MP0001968_abnormal_touch/_nociception | 1.01147162 |
| 67 | MP0002572_abnormal_emotion/affect_behav | 0.97854212 |
| 68 | MP0005310_abnormal_salivary_gland | 0.95066328 |
| 69 | MP0002735_abnormal_chemical_nociception | 0.94796754 |
| 70 | MP0000049_abnormal_middle_ear | 0.94640525 |
| 71 | MP0002882_abnormal_neuron_morphology | 0.92880499 |
| 72 | MP0006035_abnormal_mitochondrial_morpho | 0.91156814 |
| 73 | MP0003938_abnormal_ear_development | 0.90701771 |
| 74 | MP0005174_abnormal_tail_pigmentation | 0.89028008 |
| 75 | MP0004885_abnormal_endolymph | 0.88782677 |
| 76 | MP0001963_abnormal_hearing_physiology | 0.88683624 |
| 77 | MP0001324_abnormal_eye_pigmentation | 0.86563580 |
| 78 | MP0005075_abnormal_melanosome_morpholog | 0.85458651 |
| 79 | MP0003861_abnormal_nervous_system | 0.85351114 |
| 80 | MP0008872_abnormal_physiological_respon | 0.84669208 |
| 81 | MP0002697_abnormal_eye_size | 0.84278066 |
| 82 | MP0009765_abnormal_xenobiotic_induced | 0.83507722 |
| 83 | MP0010386_abnormal_urinary_bladder | 0.82150820 |
| 84 | MP0005647_abnormal_sex_gland | 0.79243451 |
| 85 | MP0002152_abnormal_brain_morphology | 0.78927332 |
| 86 | MP0003806_abnormal_nucleotide_metabolis | 0.78317441 |
| 87 | MP0002184_abnormal_innervation | 0.78207786 |
| 88 | MP0003283_abnormal_digestive_organ | 0.76831586 |
| 89 | MP0005391_vision/eye_phenotype | 0.76794998 |
| 90 | MP0003121_genomic_imprinting | 0.76776351 |
| 91 | MP0002938_white_spotting | 0.76589159 |
| 92 | MP0001486_abnormal_startle_reflex | 0.76135901 |
| 93 | MP0002063_abnormal_learning/memory/cond | 0.75107109 |
| 94 | MP0002557_abnormal_social/conspecific_i | 0.72921637 |
| 95 | MP0002095_abnormal_skin_pigmentation | 0.71508028 |
| 96 | MP0003879_abnormal_hair_cell | 0.69962901 |
| 97 | MP0002932_abnormal_joint_morphology | 0.67442980 |
| 98 | MP0003698_abnormal_male_reproductive | 0.66353347 |
| 99 | MP0004085_abnormal_heartbeat | 0.65534226 |
| 100 | MP0004215_abnormal_myocardial_fiber | 0.64778493 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Molar tooth sign on MRI (HP:0002419) | 3.78469882 |
| 2 | Abnormality of midbrain morphology (HP:0002418) | 3.78469882 |
| 3 | Pancreatic fibrosis (HP:0100732) | 3.39308733 |
| 4 | Abnormality of alanine metabolism (HP:0010916) | 3.38985819 |
| 5 | Hyperalaninemia (HP:0003348) | 3.38985819 |
| 6 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.38985819 |
| 7 | Thyroid-stimulating hormone excess (HP:0002925) | 3.27155892 |
| 8 | Fibular aplasia (HP:0002990) | 3.20557952 |
| 9 | Pancreatic cysts (HP:0001737) | 3.14334781 |
| 10 | Chronic hepatic failure (HP:0100626) | 3.08468723 |
| 11 | Type II lissencephaly (HP:0007260) | 3.04331278 |
| 12 | Adactyly (HP:0009776) | 3.02987755 |
| 13 | Concave nail (HP:0001598) | 2.99983766 |
| 14 | Gonadotropin excess (HP:0000837) | 2.97868398 |
| 15 | Confusion (HP:0001289) | 2.94591022 |
| 16 | Abolished electroretinogram (ERG) (HP:0000550) | 2.91067120 |
| 17 | Septo-optic dysplasia (HP:0100842) | 2.86021542 |
| 18 | Limb dystonia (HP:0002451) | 2.77366162 |
| 19 | Mutism (HP:0002300) | 2.71630207 |
| 20 | Inability to walk (HP:0002540) | 2.71279020 |
| 21 | Nephronophthisis (HP:0000090) | 2.68227335 |
| 22 | Retinal dysplasia (HP:0007973) | 2.67098222 |
| 23 | Decreased central vision (HP:0007663) | 2.64585837 |
| 24 | Progressive inability to walk (HP:0002505) | 2.59171783 |
| 25 | Partial agenesis of the corpus callosum (HP:0001338) | 2.58912805 |
| 26 | Abnormality of the fovea (HP:0000493) | 2.58875665 |
| 27 | True hermaphroditism (HP:0010459) | 2.53538998 |
| 28 | Genital tract atresia (HP:0001827) | 2.50140786 |
| 29 | Synostosis involving bones of the feet (HP:0009140) | 2.49018814 |
| 30 | Synostosis involving bones of the lower limbs (HP:0009138) | 2.49018814 |
| 31 | Abnormality of the renal medulla (HP:0100957) | 2.47021261 |
| 32 | Optic nerve hypoplasia (HP:0000609) | 2.45379280 |
| 33 | Ankle contracture (HP:0006466) | 2.43323673 |
| 34 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.42957670 |
| 35 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.40591496 |
| 36 | Tarsal synostosis (HP:0008368) | 2.39988886 |
| 37 | Sclerocornea (HP:0000647) | 2.39695192 |
| 38 | Bifid tongue (HP:0010297) | 2.39352689 |
| 39 | Medial flaring of the eyebrow (HP:0010747) | 2.38249834 |
| 40 | Gastrointestinal atresia (HP:0002589) | 2.37245534 |
| 41 | Atonic seizures (HP:0010819) | 2.37100568 |
| 42 | Bilateral sensorineural hearing impairment (HP:0008619) | 2.35080815 |
| 43 | Central scotoma (HP:0000603) | 2.35036923 |
| 44 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.33018161 |
| 45 | Absent/shortened dynein arms (HP:0200106) | 2.33018161 |
| 46 | Cerebellar dysplasia (HP:0007033) | 2.32475464 |
| 47 | Gait imbalance (HP:0002141) | 2.31684804 |
| 48 | Impulsivity (HP:0100710) | 2.29756225 |
| 49 | Maternal diabetes (HP:0009800) | 2.29356394 |
| 50 | Lissencephaly (HP:0001339) | 2.27409806 |
| 51 | Tubular atrophy (HP:0000092) | 2.25509626 |
| 52 | Pachygyria (HP:0001302) | 2.22490099 |
| 53 | Gaze-evoked nystagmus (HP:0000640) | 2.22305952 |
| 54 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.22045925 |
| 55 | Duplicated collecting system (HP:0000081) | 2.21644123 |
| 56 | Congenital primary aphakia (HP:0007707) | 2.20919521 |
| 57 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.20460063 |
| 58 | Microretrognathia (HP:0000308) | 2.20038570 |
| 59 | Anophthalmia (HP:0000528) | 2.17107442 |
| 60 | Hemiparesis (HP:0001269) | 2.16940607 |
| 61 | Distal arthrogryposis (HP:0005684) | 2.16157466 |
| 62 | Increased corneal curvature (HP:0100692) | 2.15152707 |
| 63 | Keratoconus (HP:0000563) | 2.15152707 |
| 64 | Carpal synostosis (HP:0009702) | 2.14756793 |
| 65 | Chorioretinal atrophy (HP:0000533) | 2.14740915 |
| 66 | Congenital stationary night blindness (HP:0007642) | 2.14297465 |
| 67 | Abnormality of chloride homeostasis (HP:0011422) | 2.14229119 |
| 68 | Abnormal ciliary motility (HP:0012262) | 2.11649387 |
| 69 | Nephrogenic diabetes insipidus (HP:0009806) | 2.08355426 |
| 70 | Postaxial hand polydactyly (HP:0001162) | 2.05670044 |
| 71 | Large for gestational age (HP:0001520) | 2.04505696 |
| 72 | Abnormality of the renal collecting system (HP:0004742) | 2.02973739 |
| 73 | Neonatal respiratory distress (HP:0002643) | 2.02659925 |
| 74 | Bilateral microphthalmos (HP:0007633) | 2.00105943 |
| 75 | Scotoma (HP:0000575) | 1.99684235 |
| 76 | Peripheral hypomyelination (HP:0007182) | 1.97223373 |
| 77 | Hyperventilation (HP:0002883) | 1.96237437 |
| 78 | Vaginal atresia (HP:0000148) | 1.96028270 |
| 79 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.95940786 |
| 80 | Broad-based gait (HP:0002136) | 1.95072666 |
| 81 | Synostosis involving bones of the hand (HP:0004278) | 1.94485933 |
| 82 | Reticulocytopenia (HP:0001896) | 1.93137915 |
| 83 | Abnormality of the renal cortex (HP:0011035) | 1.90604430 |
| 84 | Tubulointerstitial nephritis (HP:0001970) | 1.87674063 |
| 85 | Pendular nystagmus (HP:0012043) | 1.87613479 |
| 86 | Synostosis of carpal bones (HP:0005048) | 1.87337271 |
| 87 | Postaxial foot polydactyly (HP:0001830) | 1.86464516 |
| 88 | Abnormality of the labia minora (HP:0012880) | 1.85891861 |
| 89 | Patellar aplasia (HP:0006443) | 1.85830986 |
| 90 | Cystic liver disease (HP:0006706) | 1.85779274 |
| 91 | Abnormality of incisor morphology (HP:0011063) | 1.85223435 |
| 92 | Renal dysplasia (HP:0000110) | 1.84235231 |
| 93 | Short tibia (HP:0005736) | 1.84203647 |
| 94 | Abnormality of the lower motor neuron (HP:0002366) | 1.82263376 |
| 95 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.82151441 |
| 96 | Abnormality of the aortic arch (HP:0012303) | 1.81947211 |
| 97 | Anterior segment dysgenesis (HP:0007700) | 1.81467301 |
| 98 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.79747666 |
| 99 | Hypoplasia of the fovea (HP:0007750) | 1.79747666 |
| 100 | Respiratory distress (HP:0002098) | 1.79336686 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAF1 | 4.38893454 |
| 2 | ADRBK2 | 3.34221925 |
| 3 | MAP4K2 | 3.15153875 |
| 4 | TNIK | 2.94285661 |
| 5 | NTRK2 | 2.88853922 |
| 6 | MAP3K9 | 2.87952994 |
| 7 | CASK | 2.64877040 |
| 8 | PINK1 | 2.40192718 |
| 9 | FRK | 2.36381647 |
| 10 | NTRK1 | 2.27219001 |
| 11 | FLT3 | 2.12961809 |
| 12 | INSRR | 2.09538177 |
| 13 | TEC | 2.05115287 |
| 14 | BCKDK | 1.93617057 |
| 15 | SIK2 | 1.83468430 |
| 16 | WNK1 | 1.70859902 |
| 17 | DAPK2 | 1.67453776 |
| 18 | ACVR1B | 1.57633299 |
| 19 | BCR | 1.54498520 |
| 20 | MAPK13 | 1.49883659 |
| 21 | CSF1R | 1.42640951 |
| 22 | ZAK | 1.40851033 |
| 23 | CSNK1G2 | 1.39158058 |
| 24 | MARK1 | 1.38836372 |
| 25 | GRK1 | 1.38449339 |
| 26 | WNK4 | 1.36850587 |
| 27 | BMPR1B | 1.36701820 |
| 28 | OXSR1 | 1.34312415 |
| 29 | PKN2 | 1.29421412 |
| 30 | DYRK2 | 1.28952277 |
| 31 | IKBKE | 1.28938049 |
| 32 | EPHA4 | 1.25601581 |
| 33 | WNK3 | 1.21640529 |
| 34 | STK16 | 1.20603269 |
| 35 | PLK2 | 1.10617103 |
| 36 | CHUK | 1.09413401 |
| 37 | PKN1 | 1.03730708 |
| 38 | NME1 | 1.02480489 |
| 39 | KIT | 0.99715510 |
| 40 | NTRK3 | 0.96613455 |
| 41 | CSNK1G3 | 0.95461258 |
| 42 | STK39 | 0.94910106 |
| 43 | MAP3K4 | 0.94342490 |
| 44 | SRPK1 | 0.89604794 |
| 45 | STK11 | 0.85577412 |
| 46 | ADRBK1 | 0.83345988 |
| 47 | TGFBR1 | 0.83011310 |
| 48 | MAP2K7 | 0.81449678 |
| 49 | CDK19 | 0.81054160 |
| 50 | TIE1 | 0.79415672 |
| 51 | PRKCG | 0.76482406 |
| 52 | CSNK1A1L | 0.76459824 |
| 53 | ITK | 0.75935004 |
| 54 | SGK2 | 0.75209827 |
| 55 | VRK1 | 0.74004020 |
| 56 | PRKCE | 0.72025540 |
| 57 | CSNK1G1 | 0.70249721 |
| 58 | IRAK1 | 0.69722906 |
| 59 | TRIM28 | 0.67139693 |
| 60 | IKBKB | 0.64146002 |
| 61 | MAPK15 | 0.60290469 |
| 62 | CHEK2 | 0.60191493 |
| 63 | ABL2 | 0.56953861 |
| 64 | TLK1 | 0.54216624 |
| 65 | DYRK3 | 0.53364564 |
| 66 | PTK6 | 0.53035971 |
| 67 | CAMK2B | 0.52775400 |
| 68 | NUAK1 | 0.52488276 |
| 69 | NEK2 | 0.52216622 |
| 70 | PRKCH | 0.49907023 |
| 71 | CAMK2A | 0.49763086 |
| 72 | PRKCQ | 0.49623055 |
| 73 | PRKACA | 0.49101965 |
| 74 | IRAK4 | 0.47189933 |
| 75 | PAK3 | 0.46267945 |
| 76 | RPS6KA5 | 0.45152598 |
| 77 | CSNK1A1 | 0.44037695 |
| 78 | IGF1R | 0.43983554 |
| 79 | PIK3CA | 0.43129743 |
| 80 | SGK494 | 0.42328251 |
| 81 | SGK223 | 0.42328251 |
| 82 | CAMK1 | 0.42167926 |
| 83 | BTK | 0.41743909 |
| 84 | PLK3 | 0.41354516 |
| 85 | PRKG1 | 0.40495171 |
| 86 | PLK1 | 0.40399612 |
| 87 | TXK | 0.37700524 |
| 88 | RPS6KB1 | 0.36938428 |
| 89 | MKNK1 | 0.36729943 |
| 90 | PRKD1 | 0.35382109 |
| 91 | STK4 | 0.34657224 |
| 92 | IRAK2 | 0.34473461 |
| 93 | AKT1 | 0.32631922 |
| 94 | PIK3CG | 0.32491622 |
| 95 | CAMK2D | 0.32483537 |
| 96 | EPHA3 | 0.31933486 |
| 97 | OBSCN | 0.31157984 |
| 98 | PRKCZ | 0.30580841 |
| 99 | GRK5 | 0.29593076 |
| 100 | JAK2 | 0.29386785 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 3.77620724 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.98537521 |
| 3 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.91771007 |
| 4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.80413575 |
| 5 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.63930110 |
| 6 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.49975786 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.48924938 |
| 8 | ABC transporters_Homo sapiens_hsa02010 | 2.17340568 |
| 9 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.08847823 |
| 10 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.99370065 |
| 11 | Morphine addiction_Homo sapiens_hsa05032 | 1.98714513 |
| 12 | Olfactory transduction_Homo sapiens_hsa04740 | 1.86311220 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 1.80180984 |
| 14 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.79478930 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.71368087 |
| 16 | Taste transduction_Homo sapiens_hsa04742 | 1.70311446 |
| 17 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.69808810 |
| 18 | Asthma_Homo sapiens_hsa05310 | 1.63950854 |
| 19 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.63568235 |
| 20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.60299723 |
| 21 | GABAergic synapse_Homo sapiens_hsa04727 | 1.59815621 |
| 22 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.53878638 |
| 23 | Salivary secretion_Homo sapiens_hsa04970 | 1.50127641 |
| 24 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.42834652 |
| 25 | Circadian entrainment_Homo sapiens_hsa04713 | 1.39427559 |
| 26 | Histidine metabolism_Homo sapiens_hsa00340 | 1.37701475 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.36119353 |
| 28 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.35211440 |
| 29 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.33846555 |
| 30 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.29948993 |
| 31 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.26799620 |
| 32 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.25744807 |
| 33 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.22173591 |
| 34 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.20577085 |
| 35 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.19344236 |
| 36 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.14922382 |
| 37 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.13144435 |
| 38 | Ribosome_Homo sapiens_hsa03010 | 1.11555647 |
| 39 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.10912466 |
| 40 | Retinol metabolism_Homo sapiens_hsa00830 | 1.10412253 |
| 41 | Parkinsons disease_Homo sapiens_hsa05012 | 1.09261060 |
| 42 | Phototransduction_Homo sapiens_hsa04744 | 1.05585104 |
| 43 | Cocaine addiction_Homo sapiens_hsa05030 | 1.04437865 |
| 44 | Homologous recombination_Homo sapiens_hsa03440 | 0.97222494 |
| 45 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.95559560 |
| 46 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.95289675 |
| 47 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.92040725 |
| 48 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.91443340 |
| 49 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.91013301 |
| 50 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.86295431 |
| 51 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.85661723 |
| 52 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.85347213 |
| 53 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.84837845 |
| 54 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.79950696 |
| 55 | Protein export_Homo sapiens_hsa03060 | 0.79765167 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.79706152 |
| 57 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.78961356 |
| 58 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.78637754 |
| 59 | Huntingtons disease_Homo sapiens_hsa05016 | 0.78017072 |
| 60 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.76567348 |
| 61 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.75738734 |
| 62 | Insulin secretion_Homo sapiens_hsa04911 | 0.75634834 |
| 63 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.74395923 |
| 64 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.73978937 |
| 65 | Renin secretion_Homo sapiens_hsa04924 | 0.73948528 |
| 66 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.72759130 |
| 67 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.72693786 |
| 68 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.72086969 |
| 69 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.71833668 |
| 70 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.71603706 |
| 71 | Peroxisome_Homo sapiens_hsa04146 | 0.71094726 |
| 72 | Allograft rejection_Homo sapiens_hsa05330 | 0.70530449 |
| 73 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.68455977 |
| 74 | Long-term depression_Homo sapiens_hsa04730 | 0.68373221 |
| 75 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.65337057 |
| 76 | Axon guidance_Homo sapiens_hsa04360 | 0.64441204 |
| 77 | Alzheimers disease_Homo sapiens_hsa05010 | 0.64063844 |
| 78 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.59698177 |
| 79 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.58293775 |
| 80 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.56664427 |
| 81 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.55452904 |
| 82 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.54829787 |
| 83 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.53761166 |
| 84 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52174952 |
| 85 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.50895427 |
| 86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.50036768 |
| 87 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.50010184 |
| 88 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.49219325 |
| 89 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.47933172 |
| 90 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.47550336 |
| 91 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.46553556 |
| 92 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.45959177 |
| 93 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43554699 |
| 94 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.43388396 |
| 95 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.41931793 |
| 96 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.41885686 |
| 97 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.39527495 |
| 98 | Purine metabolism_Homo sapiens_hsa00230 | 0.37912859 |
| 99 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.37338210 |
| 100 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.35963691 |

